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130049-85-3,MFCD19704869
Catalog No.:AA009X7Y

130049-85-3 | (R)-9-Hydroxy Risperidone

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
4 weeks  
$947.00   $663.00
- +
2mg
4 weeks  
$1,554.00   $1,088.00
- +
5mg
4 weeks  
$3,160.00   $2,212.00
- +
10mg
3 weeks  
$4,428.00   $3,099.00
- +
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA009X7Y
Chemical Name:
(R)-9-Hydroxy Risperidone
CAS Number:
130049-85-3
Molecular Formula:
C23H27FN4O3
Molecular Weight:
426.4839
MDL Number:
MFCD19704869
SMILES:
Fc1ccc2c(c1)onc2C1CCN(CC1)CCc1c(C)nc2n(c1=O)CCC[C@H]2O
Properties
Computed Properties
 
Complexity:
764  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
XLogP3:
2.2  

Literature

Title: Relationship between inflammation and metabolic syndrome following treatment with paliperidone for schizophrenia.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20121203

Title: Paliperidone extended release: in adolescents with schizophrenia.

Journal: Paediatric drugs 20121201

Title: An evaluation of using rat-derived single-dose neuropharmacokinetic parameters to project accurately large animal unbound brain drug concentrations.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20121101

Title: Liquid chromatography-tandem mass spectrometry method for determination of five antidepressants and four atypical antipsychotics and their main metabolites in human serum.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20121015

Title: Blonanserin, a novel atypical antipsychotic agent not actively transported as substrate by P-glycoprotein.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20121001

Title: Rabbit syndrome following discontinuation of paliperidone in a patient with schizoaffective disorder.

Journal: Journal of clinical psychopharmacology 20121001

Title: New serotonin/dopamine antagonists for the treatment of schizophrenia: are we making real progress?

Journal: Clinical schizophrenia & related psychoses 20121001

Title: Pharmacological and clinical profile of recently approved second-generation antipsychotics: implications for treatment of schizophrenia in older patients.

Journal: Drugs & aging 20121001

Title: Solid phase microextraction and LC-MS/MS for the determination of paliperidone after stereoselective fungal biotransformation of risperidone.

Journal: Analytica chimica acta 20120912

Title: Paliperidone for irritability in adolescents and young adults with autistic disorder.

Journal: Psychopharmacology 20120901

Title: Paliperidone ER versus risperidone for neurocognitive function in patients with schizophrenia: a randomized, open-label, controlled trial.

Journal: International clinical psychopharmacology 20120901

Title: Effects of aripiprazole and its active metabolite dehydroaripiprazole on the activities of drug efflux transporters expressed both in the intestine and at the blood-brain barrier.

Journal: Biopharmaceutics & drug disposition 20120901

Title: Body weight and metabolic adverse effects of asenapine, iloperidone, lurasidone and paliperidone in the treatment of schizophrenia and bipolar disorder: a systematic review and exploratory meta-analysis.

Journal: CNS drugs 20120901

Title: Second-generation long-acting injectable antipsychotic agents: an overview.

Journal: Drug and therapeutics bulletin 20120901

Title: Psychotropic drug effects on gene transcriptomics relevant to Parkinson's disease.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20120807

Title: The effect of paliperidone extended release on subjective well-being and responses in patients with schizophrenia.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20120807

Title: A systematic review of meta-analyses of the efficacy of oral atypical antipsychotics for the treatment of adult patients with schizophrenia.

Journal: Expert opinion on pharmacotherapy 20120801

Title: Population pharmacokinetic analysis of risperidone and 9-hydroxyrisperidone with genetic polymorphisms of CYP2D6 and ABCB1.

Journal: Journal of pharmacokinetics and pharmacodynamics 20120801

Title: Flexible dosing with paliperidone ER in the treatment of patients with acutely exacerbated schizophrenia: results from a single-arm, open-label study.

Journal: Current medical research and opinion 20120801

Title: Paliperidone: a review of clinical trial data and clinical implications.

Journal: Clinical drug investigation 20120801

Title: A cross-sectional study of plasma risperidone levels with risperidone long-acting injectable: implications for dopamine D2 receptor occupancy during maintenance treatment in schizophrenia.

Journal: The Journal of clinical psychiatry 20120801

Title: Pharmacokinetic-pharmacodynamic modeling of the D₂ and 5-HT (2A) receptor occupancy of risperidone and paliperidone in rats.

Journal: Pharmaceutical research 20120701

Title: Oral paliperidone extended-release: chemistry, pharmacodynamics, pharmacokinetics and metabolism, clinical efficacy, safety and tolerability.

Journal: Expert opinion on drug metabolism & toxicology 20120701

Title: Weight gain and glucose dysregulation with second-generation antipsychotics and antidepressants: a review for primary care physicians.

Journal: Postgraduate medicine 20120701

Title: Paliperidone palmitate for schizophrenia.

Journal: The Cochrane database of systematic reviews 20120613

Title: Different impacts of aquaporin 4 and MAOA allele variation among olanzapine, risperidone, and paliperidone in schizophrenia.

Journal: Journal of clinical psychopharmacology 20120601

Title: Risperidone and total 9-hydroxyrisperidone in relation to prescribed dose and other factors: data from a therapeutic drug monitoring service, 2002-2010.

Journal: Therapeutic drug monitoring 20120601

Title: Comparative fasting bioavailability of dispersible and conventional tablets of risperidone: a single-dose, randomized-sequence, open-label, two-period crossover study in healthy male Chinese volunteers.

Journal: Clinical therapeutics 20120601

Title: Rash in psychiatric and nonpsychiatric adolescent patients receiving lamotrigine in Korea: a retrospective cohort study.

Journal: Psychiatry investigation 20120601

Title: Summary of the comparative effectiveness review on off-label use of atypical antipsychotics.

Journal: Journal of managed care pharmacy : JMCP 20120601

Title: Extended-release intramuscular paliperidone palmitate: a review of its use in the treatment of schizophrenia.

Journal: Drugs 20120528

Title: Design of a long-term antipsychotic in situ forming implant and its release control method and mechanism.

Journal: International journal of pharmaceutics 20120510

Title: Combination of citalopram plus paliperidone is better than citalopram alone in the treatment of somatoform disorder: results of a 6-week randomized study.

Journal: International clinical psychopharmacology 20120501

Title: A randomized, placebo- and active-controlled study of paliperidone extended-release as maintenance treatment in patients with bipolar I disorder after an acute manic or mixed episode.

Journal: Journal of affective disorders 20120501

Title: Different safety profiles of risperidone and paliperidone extended-release: a double-blind, placebo-controlled trial with healthy volunteers.

Journal: Human psychopharmacology 20120501

Title: Effect of cytochrome P450 3A4 inhibitor ketoconazole on risperidone pharmacokinetics in healthy volunteers.

Journal: Journal of clinical pharmacy and therapeutics 20120401

Title: Relationship between dose, drug levels, and D2 receptor occupancy for the atypical antipsychotics risperidone and paliperidone.

Journal: The Journal of pharmacology and experimental therapeutics 20120401

Title: Predicting plasma concentration of risperidone associated with dosage change: a population pharmacokinetic study.

Journal: Therapeutic drug monitoring 20120401

Title: A stability-indicating ultra-performance liquid chromatographic method for estimation of related substances and degradants in paliperidone active pharmaceutical ingredient and its pharmaceutical dosage forms.

Journal: Journal of chromatographic science 20120401

Title: Species comparison of in vivo P-glycoprotein-mediated brain efflux using mdr1a-deficient rats and mice.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20120301

Title: Atypical antipsychotic-induced mania/hypomania: a review of recent case reports and clinical studies.

Journal: International journal of psychiatry in clinical practice 20120301

Title: Adjunctive armodafinil for negative symptoms in adults with schizophrenia: a double-blind, placebo-controlled study.

Journal: Schizophrenia research 20120301

Title: Loxapine P-glycoprotein interactions in vitro.

Journal: Drug metabolism letters 20120301

Title: Interactions between antiepileptics and second-generation antipsychotics.

Journal: Expert opinion on drug metabolism & toxicology 20120301

Title: Prolongation of cardiac ventricular repolarization under paliperidone: how and how much?

Journal: Journal of cardiovascular pharmacology 20120301

Title: Publication bias in antipsychotic trials: an analysis of efficacy comparing the published literature to the US Food and Drug Administration database.

Journal: PLoS medicine 20120301

Title: Acute renal failure after paliperidone overdose: a case report.

Journal: Journal of clinical psychopharmacology 20120201

Title: Neurotoxic/neuroprotective activity of haloperidol, risperidone and paliperidone in neuroblastoma cells.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20120110

Title: Evaluation of the efficacy and safety of paliperidone extended-release in the treatment of acute mania: a randomized, double-blind, dose-response study.

Journal: Journal of affective disorders 20120101

Title: QT prolongation of the antipsychotic risperidone is predominantly related to its 9-hydroxy metabolite paliperidone.

Journal: Human psychopharmacology 20120101

Title: Oral-paliperidone-induced tardive dyskinesia: a case report.

Journal: General hospital psychiatry 20120101

Title: Anaphylactoid reaction to paliperidone palmitate extended-release injectable suspension in a patient tolerant of oral risperidone.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120101

Title: Effects of paliperidone extended release on the symptoms and functioning of schizophrenia.

Journal: BMC clinical pharmacology 20120101

Title: The neuroprotective disease-modifying potential of psychotropics in Parkinson's disease.

Journal: Parkinson's disease 20120101

Title: [Efficacy, tolerability and safety of paliperidone extended-release in the treatment of schizophrenia and schizoaffective disorder].

Journal: Rivista di psichiatria 20120101

Title: Survey of methadone-drug interactions among patients of methadone maintenance treatment program in Taiwan.

Journal: Substance abuse treatment, prevention, and policy 20120101

Title: A patient perspective of the impact of medication side effects on adherence: results of a cross-sectional nationwide survey of patients with schizophrenia.

Journal: BMC psychiatry 20120101

Title: A one-year prospective study of the safety, tolerability and pharmacokinetics of the highest available dose of paliperidone palmitate in patients with schizophrenia.

Journal: BMC psychiatry 20120101

Title: Enhanced brain disposition and effects of Δ9-tetrahydrocannabinol in P-glycoprotein and breast cancer resistance protein knockout mice.

Journal: PloS one 20120101

Title: Critical appraisal of lurasidone in the management of schizophrenia.

Journal: Neuropsychiatric disease and treatment 20120101

Title: The role of paliperidone extended release for the treatment of bipolar disorder.

Journal: Neuropsychiatric disease and treatment 20120101

Title: Antidopaminergic drugs and acute pancreatitis: a population-based study.

Journal: BMJ open 20120101

Title: Atypical antipsychotic drugs, schizophrenia, and metabolic syndrome in non-Euro-American societies.

Journal: Clinical neuropharmacology 20120101

Title: Genetic polymorphisms in CYP2E1: association with schizophrenia susceptibility and risperidone response in the Chinese Han population.

Journal: PloS one 20120101

Title: Reduced gray to white matter tissue intensity contrast in schizophrenia.

Journal: PloS one 20120101

Title: An audit of first prescription of new patients attending a psychiatry walk-in-clinic in north India.

Journal: Indian journal of pharmacology 20120101

Title: Role of aripiprazole in treatment-resistant schizophrenia.

Journal: Neuropsychiatric disease and treatment 20120101

Title: Effect of the cytochrome P450 2D6*10 allele on risperidone metabolism in Japanese psychiatric patients.

Journal: Human psychopharmacology 20120101

Title: Cost-effectiveness analysis of antipsychotics in reducing schizophrenia relapses.

Journal: Health economics review 20120101

Title: Management of antipsychotic treatment discontinuation and interruptions using model-based simulations.

Journal: Clinical pharmacology : advances and applications 20120101

Title: Treatment with paliperidone in children with behavior disorders previously treated with risperidone: an open-label trial.

Journal: Clinical neuropharmacology 20120101

Title: Long-term tolerability of once-monthly injectable paliperidone palmitate in subjects with recently diagnosed schizophrenia.

Journal: Neuropsychiatric disease and treatment 20120101

Title: Role of long-acting injectable second-generation antipsychotics in the treatment of first-episode schizophrenia: a clinical perspective.

Journal: Schizophrenia research and treatment 20120101

Title: Aripiprazole reverses paliperidone-induced hyperprolactinemia.

Journal: Actas espanolas de psiquiatria 20120101

Title: A randomized, double-blind study of paliperidone extended-release in treatment of acute schizophrenia in adolescents.

Journal: Biological psychiatry 20111215

Title: Social interaction and drug attitude effectiveness in patients with schizophrenia.

Journal: The Psychiatric quarterly 20111201

Title: Paliperidone: 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]eth-yl}-9-hy-droxy-2-methyl-1,6,7,8,9,9a-hexa-hydro-pyrido[1,2-a]pyrimidin-4-one.

Journal: Acta crystallographica. Section E, Structure reports online 20111101

Title: Neuroprotection of paliperidone on SH-SY5Y cells against β-amyloid peptide(25-35), N-methyl-4-phenylpyridinium ion, and hydrogen peroxide-induced cell death.

Journal: Psychopharmacology 20111001

Title: Mechanism-based pharmacokinetic-pharmacodynamic modeling of the dopamine D2 receptor occupancy of olanzapine in rats.

Journal: Pharmaceutical research 20111001

Title: Effects of acute paliperidone palmitate treatment in subjects with schizophrenia recently treated with oral risperidone.

Journal: Schizophrenia research 20111001

Title: Comparing the influence of dopamine D₂ polymorphisms and plasma drug concentrations on the clinical response to risperidone.

Journal: Journal of clinical psychopharmacology 20111001

Title: Efficacy and comparative effectiveness of atypical antipsychotic medications for off-label uses in adults: a systematic review and meta-analysis.

Journal: JAMA 20110928

Title: Effects of risperidone and paliperidone pre-treatment on locomotor response following prenatal immune activation.

Journal: Journal of psychiatric research 20110901

Title: Influence of ABCB1 genetic polymorphisms on the pharmacokinetics of risperidone in healthy subjects with CYP2D6*10/*10.

Journal: British journal of pharmacology 20110901

Title: Effect of paliperidone and risperidone on extracellular glutamate in the prefrontal cortex of rats exposed to prenatal immune activation or MK-801.

Journal: Neuroscience letters 20110818

Title: Metabolic and neurological complications of second-generation antipsychotic use in children: a systematic review and meta-analysis of randomized controlled trials.

Journal: Drug safety 20110801

Title: Relationship between P-glycoprotein and second-generation antipsychotics.

Journal: Pharmacogenomics 20110801

Title: Paliperidone overdose with delayed onset of toxicity.

Journal: Annals of emergency medicine 20110701

Title: MultiSimplex optimization of chromatographic separation and dansyl derivatization conditions in the ultra performance liquid chromatography-tandem mass spectrometry analysis of risperidone, 9-hydroxyrisperidone, monoamine and amino acid neurotransmitters in human urine.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110701

Title: A comparative study of paliperidone palmitate and risperidone long-acting injectable therapy in schizophrenia.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20110601

Title: Prolongation of cardiac ventricular repolarization under paliperidone: how and how much?

Journal: Journal of cardiovascular pharmacology 20110601

Title: Antipsychotic drug use and community-acquired pneumonia.

Journal: Current infectious disease reports 20110601

Title: Differential effects of antipsychotic medications on polyunsaturated fatty acid biosynthesis in rats: Relationship with liver delta6-desaturase expression.

Journal: Schizophrenia research 20110601

Title: Atypical antipsychotic medications increase postprandial triglyceride and glucose levels in male rats: relationship with stearoyl-CoA desaturase activity.

Journal: Schizophrenia research 20110601

Title: Development of controlled-release matrix tablet of risperidone: influence of Methocel®- and Ethocel®-based novel polymeric blend on in vitro drug release and bioavailability.

Journal: AAPS PharmSciTech 20110601

Title: Use of paliperidone in elderly patients with schizophrenia and schizoaffective disorder: a prospective open-label short-term pilot study.

Journal: Journal of clinical psychopharmacology 20110601

Title: Comparative pharmacokinetics and bioequivalence of two tablet formulations of 2 mg risperidone in healthy Thai male volunteers.

Journal: International journal of clinical pharmacology and therapeutics 20110601

Title: Oral paliperidone: a review of its use in the management of schizoaffective disorder.

Journal: CNS drugs 20110601

Title: [Pharmacological properties of paliperidone ER (INVEGA(®)) and results of its clinical studies].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20110601

Title: Routine outcomes monitoring to support improving care for schizophrenia: report from the VA Mental Health QUERI.

Journal: Community mental health journal 20110401

Title: Lithium, but not fluoxetine or the corticotropin-releasing factor receptor 1 receptor antagonist R121919, increases cell proliferation in the adult dentate gyrus.

Journal: The Journal of pharmacology and experimental therapeutics 20110401

Title: Cost-effectiveness of olanzapine long-acting injection in the treatment of patients with schizophrenia in the United States: a micro-simulation economic decision model.

Journal: Current medical research and opinion 20110401

Title: Paliperidone augmentation for treatment-resistant depression: a case report.

Journal: Journal of clinical psychopharmacology 20110401

Title: Predictors of risperidone and 9-hydroxyrisperidone serum concentration in children and adolescents.

Journal: Journal of child and adolescent psychopharmacology 20110401

Title: Risk of arrest in persons with schizophrenia and bipolar disorder in a Florida Medicaid program: the role of atypical antipsychotics, conventional neuroleptics, and routine outpatient behavioral health services.

Journal: The Journal of clinical psychiatry 20110401

Title: Newer molecules in the treatment of schizophrenia: A clinical update.

Journal: Indian journal of pharmacology 20110401

Title: Paliperidone extended-release as adjunctive therapy to lithium or valproate in the treatment of acute mania: a randomized, placebo-controlled study.

Journal: Journal of affective disorders 20110301

Title: Country differences in patient characteristics and treatment in schizophrenia: data from a physician-based survey in Europe.

Journal: European psychiatry : the journal of the Association of European Psychiatrists 20110301

Title: Are the long-acting intramuscular formulations of risperidone or paliperidone palmitate associated with post-injection delirium/sedation syndrome? An assessment of safety databases.

Journal: Current drug safety 20110201

Title: Change in employment status over 52 weeks in patients with schizophrenia: an observational study.

Journal: Current medical research and opinion 20110201

Title: The role of serotonin receptors in the action of atypical antipsychotic drugs.

Journal: Current opinion in pharmacology 20110201

Title: Analysis of risperidone and 9-hydroxyrisperidone in human plasma, urine and saliva by MEPS-LC-UV.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110115

Title: Switching to aripiprazole as a strategy for weight reduction: a meta-analysis in patients suffering from schizophrenia.

Journal: Journal of obesity 20110101

Title: Evaluation of the effect of paliperidone extended release and quetiapine on corrected QT intervals: a randomized, double-blind, placebo-controlled study.

Journal: International clinical psychopharmacology 20110101

Title: The use of PET imaging in studying cognition, genetics and pharmacotherapeutic interventions in schizophrenia.

Journal: Expert review of neurotherapeutics 20110101

Title: Paliperidone ER and oral risperidone in patients with schizophrenia: a comparative database analysis.

Journal: BMC psychiatry 20110101

Title: Weight gain, obesity, and psychotropic prescribing.

Journal: Journal of obesity 20110101

Title: Cardiac safety of the electroconvulsive therapy-paliperidone combination: a preliminary study.

Journal: General hospital psychiatry 20110101

Title: Class effect of pharmacotherapy in bipolar disorder: fact or misbelief?

Journal: Annals of general psychiatry 20110101

Title: Paliperidone extended-release: does it have a place in antipsychotic therapy?

Journal: Drug design, development and therapy 20110101

Title: Onset of efficacy with acute long-acting injectable paliperidone palmitate treatment in markedly to severely ill patients with schizophrenia: post hoc analysis of a randomized, double-blind clinical trial.

Journal: Annals of general psychiatry 20110101

Title: Epidemiology of tardive dyskinesia before and during the era of modern antipsychotic drugs.

Journal: Handbook of clinical neurology 20110101

Title: Number needed to treat and number needed to harm with paliperidone palmitate relative to long-acting haloperidol, bromperidol, and fluphenazine decanoate for treatment of patients with schizophrenia.

Journal: Neuropsychiatric disease and treatment 20110101

Title: Acute dystonia associated with paliperidone overdose.

Journal: Psychosomatics 20110101

Title: Onset of efficacy and tolerability following the initiation dosing of long-acting paliperidone palmitate: post-hoc analyses of a randomized, double-blind clinical trial.

Journal: BMC psychiatry 20110101

Title: Dose pattern and effectiveness of paliperidone extended-release tablets in patients with schizophrenia.

Journal: Clinical neuropharmacology 20110101

Title: Clinical potential of lurasidone in the management of schizophrenia.

Journal: Therapeutics and clinical risk management 20110101

Title: [Determination of blood/serum ratios of different forensically relevant analytes in authentic samples].

Journal: Archiv fur Kriminologie 20110101

Title: Paliperidone ER in the Treatment of Borderline Personality Disorder: A Pilot Study of Efficacy and Tolerability.

Journal: Depression research and treatment 20110101

Title: An in vitro evaluation of guanfacine as a substrate for P-glycoprotein.

Journal: Neuropsychiatric disease and treatment 20110101

Title: The cost associated with administering risperidone long-acting injections in the Australian community.

Journal: BMC health services research 20110101

Title: Improvement of oral dyskinesia after switching from aripiprazole to paliperidone: a case report.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20110101

Title: Manic symptoms during a switch from risperidone to paliperidone: a case report.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20110101

Title: Stability indicating HPLC determination of risperidone in bulk drug and pharmaceutical formulations.

Journal: International journal of analytical chemistry 20110101

Title: Use of non-parametric item response theory to develop a shortened version of the Positive and Negative Syndrome Scale (PANSS).

Journal: BMC psychiatry 20110101

Title: Clinical utility of the risperidone formulations in the management of schizophrenia.

Journal: Neuropsychiatric disease and treatment 20110101

Title: Emergence of neuroleptic malignant syndrome while switching between risperidone and paliperidone.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20110101

Title: Tardive Tourette-like syndrome in a patient treated with paliperidone.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20110101

Title: [Hyperprolactinemia in mentally ill patients].

Journal: Acta medica portuguesa 20110101

Title: Tolerability and efficacy of paliperidone ER compared to olanzapine in the treatment of schizophrenia: A randomized, double-blind, multicentric trial.

Journal: Industrial psychiatry journal 20110101

Title: Effect of cyamemazine on the steady-state plasma concentrations of risperidone and 9-hydroxyrisperidone: a preliminary retrospective study.

Journal: Therapeutic drug monitoring 20101201

Title: Comparison of the agonist-antagonist interaction model and the pool model for the effect of remoxipride on prolactin.

Journal: British journal of clinical pharmacology 20101201

Title: Acute akathisia with quetiapine: A case report and review of literature.

Journal: Indian journal of pharmacology 20101201

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20101201

Title: Tolerability of paliperidone: a meta-analysis of randomized, controlled trials.

Journal: International clinical psychopharmacology 20101101

Title: Armodafinil as adjunctive therapy in adults with cognitive deficits associated with schizophrenia: a 4-week, double-blind, placebo-controlled study.

Journal: The Journal of clinical psychiatry 20101101

Title: A population pharmacokinetic evaluation of the influence of CYP2D6 genotype on risperidone metabolism in patients with acute episode of schizophrenia.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20101009

Title: The effect of metformin on anthropometrics and insulin resistance in patients receiving atypical antipsychotic agents: a meta-analysis.

Journal: The Journal of clinical psychiatry 20101001

Title: Elevated plasma γ-aminobutyrate/glutamate ratio and responses to risperidone antipsychotic treatment in schizophrenia.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20101001

Title: Differential effects of antipsychotic and antidepressant drugs on neurogenic regions in rats.

Journal: Brain research 20101001

Title: Paliperidone extended-release in schizoaffective disorder: a randomized, controlled study comparing a flexible dose with placebo in patients treated with and without antidepressants and/or mood stabilizers.

Journal: Journal of clinical psychopharmacology 20101001

Title: Effects of CYP2D6 genotype on the pharmacokinetics, pharmacodynamics, and safety of risperidone in healthy volunteers.

Journal: Journal of clinical psychopharmacology 20101001

Title: Paliperidone extended-release: a review of efficacy and tolerability in schizophrenia, schizoaffective disorder and bipolar mania.

Journal: Expert opinion on pharmacotherapy 20101001

Title: Glioblastoma chemotherapy adjunct via potent serotonin receptor-7 inhibition using currently marketed high-affinity antipsychotic medicines.

Journal: British journal of pharmacology 20101001

Title: Adjunctive use of atypical antipsychotics for treatment-resistant generalized anxiety disorder.

Journal: Pharmacotherapy 20100901

Title: Comparative bioavailability of two risperidone orodispersible tablet products after single dose administration.

Journal: International journal of clinical pharmacology and therapeutics 20100901

Title: Relative bioavailability and pharmacokinetic comparison of two 2-mg risperidone tablet formulations: A single dose, randomized-sequence, double-blind, 2-way crossover study in healthy male volunteers in Thailand.

Journal: Clinical therapeutics 20100901

Title: Serum concentrations of paliperidone versus risperidone and clinical effects.

Journal: European journal of clinical pharmacology 20100801

Title: Neuroleptic malignant syndrome secondary to aripiprazole initiation in a clozapine-intolerant patient.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100801

Title: Studies on the acute toxicity, pharmacokinetics and pharmacodynamics of paliperidone derivatives--comparison to paliperidone and risperidone in mice and rats.

Journal: Basic & clinical pharmacology & toxicology 20100801

Title: One-year open-label safety and efficacy study of paliperidone extended-release tablets in patients with schizophrenia.

Journal: CNS spectrums 20100801

Title: Paliperidone extended release: a review of its use in the management of schizophrenia.

Journal: Drugs 20100709

Title: Relationship between response to risperidone, plasma concentrations of risperidone and CYP3A4 polymorphisms in schizophrenia patients.

Journal: Journal of psychopharmacology (Oxford, England) 20100701

Title: A comparison of serum prolactin concentrations after administration of paliperidone extended-release and risperidone tablets in patients with schizophrenia.

Journal: Journal of psychopharmacology (Oxford, England) 20100701

Title: Atypical antipsychotic metabolism and excretion.

Journal: Current drug metabolism 20100701

Title: Single-dose pharmacokinetics of paliperidone extended-release tablets in healthy Chinese subjects.

Journal: Human psychopharmacology 20100701

Title: Paliperidone palmitate injection: Its efficacy, safety and tolerability in schizophrenia.

Journal: Drugs of today (Barcelona, Spain : 1998) 20100701

Title: Real-world Data on Atypical Antipsychotic Medication Side Effects.

Journal: Psychiatry (Edgmont (Pa. : Township)) 20100701

Title: Analysis of risperidone and its metabolite in plasma and saliva by LC with coulometric detection and a novel MEPS procedure.

Journal: Talanta 20100615

Title: Effect of CYP2D6, CYP3A5, and MDR1 genetic polymorphisms on the pharmacokinetics of risperidone and its active moiety.

Journal: Journal of clinical pharmacology 20100601

Title: Relevance of norepinephrine-dopamine interactions in the treatment of major depressive disorder.

Journal: CNS neuroscience & therapeutics 20100601

Title: Hyperprolactinaemia during treatment with paliperidone.

Journal: Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists 20100601

Title: [Secondary data for budget impact analyses].

Journal: Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)) 20100601

Title: Efficacy and tolerability of paliperidone ER and other oral atypical antipsychotics in schizophrenia.

Journal: International journal of clinical pharmacology and therapeutics 20100601

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20100601

Title: Psychometric evaluation of the Medication Satisfaction Questionnaire (MSQ) to assess satisfaction with antipsychotic medication among schizophrenia patients.

Journal: Schizophrenia research 20100501

Title: Medication satisfaction in schizophrenia: a blinded-initiation study of paliperidone extended release in patients suboptimally responsive to risperidone.

Journal: International clinical psychopharmacology 20100501

Title: A randomized, double-blind, placebo-controlled study of 2 dose ranges of paliperidone extended-release in the treatment of subjects with schizoaffective disorder.

Journal: The Journal of clinical psychiatry 20100501

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20100501

Title: A randomized, placebo- and active-controlled study of paliperidone extended release for the treatment of acute manic and mixed episodes of bipolar I disorder.

Journal: Bipolar disorders 20100501

Title: Catatonia associated with initiating paliperidone treatment.

Journal: The western journal of emergency medicine 20100501

Title: Efficacy and safety of atypical antipsychotic drugs (quetiapine, risperidone, aripiprazole and paliperidone) compared with placebo or typical antipsychotic drugs for treating refractory schizophrenia: overview of systematic reviews.

Journal: Sao Paulo medical journal = Revista paulista de medicina 20100501

Title: Physicochemical characterization of neuroleptics. Relative stability of 7- and 9-hydroxyrisperidones and their protonated forms in gas phase and in solution.

Journal: European journal of medicinal chemistry 20100401

Title: Paliperidone use in the elderly.

Journal: Current drug safety 20100401

Title: Manic symptoms induced by paliperidone.

Journal: Journal of clinical psychopharmacology 20100401

Title: Paliperidone overdose in a patient with schizophrenia.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20100317

Title: MDR1 gene polymorphisms and response to acute risperidone treatment.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20100317

Title: Effects of quetiapine, risperidone, 9-hydroxyrisperidone and ziprasidone on the survival of human neuronal and immune cells in vitro.

Journal: Journal of psychopharmacology (Oxford, England) 20100301

Title: A comparison of continuous subcutaneous paliperidone infusion and repeated subcutaneous injection of risperidone free-base in rats.

Journal: European psychiatry : the journal of the Association of European Psychiatrists 20100301

Title: The risk of death among adult participants in trials of antipsychotic drugs in schizophrenia.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20100301

Title: Modeling the effectiveness of paliperidone ER and olanzapine in schizophrenia: meta-analysis of 3 randomized, controlled clinical trials.

Journal: Journal of clinical pharmacology 20100301

Title: Intramuscular paliperidone palmitate.

Journal: CNS drugs 20100301

Title: Serum concentrations, therapeutic response and side effects in children and adolescents with impulsive-aggressive symptoms during risperidone therapy.

Journal: Pharmacopsychiatry 20100301

Title: Practical guidance for dosing and switching paliperidone palmitate treatment in patients with schizophrenia.

Journal: Current medical research and opinion 20100201

Title: Possible neuroleptic malignant syndrome during paliperidone administration: a case report.

Journal: Journal of clinical psychopharmacology 20100201

Title: Paliperidone for irritability in autistic disorder.

Journal: Journal of child and adolescent psychopharmacology 20100201

Title: Paliperidone extended-release tablets in patients with recently diagnosed schizophrenia.

Journal: Early intervention in psychiatry 20100201

Title: Measuring social functioning with the personal and social performance scale in patients with acute symptoms of schizophrenia: interpretation of results of a pooled analysis of three Phase III trials of paliperidone extended-release tablets.

Journal: Clinical therapeutics 20100201

Title: Efficacy and safety of paliperidone extended-release in schizophrenia patients with prominent affective symptoms.

Journal: Journal of affective disorders 20100101

Title: Paliperidone palmitate - review of the efficacy, safety and cost of a new second-generation depot antipsychotic medication.

Journal: International journal of clinical practice 20100101

Title: The pharmacokinetics of paliperidone versus risperidone.

Journal: Psychosomatics 20100101

Title: New atypical antipsychotics for schizophrenia: iloperidone.

Journal: Drug design, development and therapy 20100101

Title: Predicting hospital admission and discharge with symptom or function scores in patients with schizophrenia: pooled analysis of a clinical trial extension.

Journal: Annals of general psychiatry 20100101

Title: Long-acting injectable antipsychotics: focus on olanzapine pamoate.

Journal: Neuropsychiatric disease and treatment 20100101

Title: Emerging treatments in the management of bipolar disorder - focus on risperidone long acting injection.

Journal: Neuropsychiatric disease and treatment 20100101

Title: Once-monthly paliperidone injection for the treatment of schizophrenia.

Journal: Neuropsychiatric disease and treatment 20100101

Title: Baseline characteristics and initial treatment decisions for patients with schizophrenia at risk of treatment nonadherence.

Journal: Patient preference and adherence 20100101

Title: Patient perspectives on use of long-acting antipsychotics in bipolar disorder: focus on risperidone injection.

Journal: Patient preference and adherence 20100101

Title: Hyperprolactinemia with antipsychotic drugs in children and adolescents.

Journal: International journal of pediatric endocrinology 20100101

Title: Exploratory analysis of psychiatric-related utilization and costs associated with paliperidone ER compared with other oral atypical antipsychotics using pharmacy claims from an administrative database.

Journal: Journal of medical economics 20100101

Title: Role of paliperidone extended-release in treatment of schizoaffective disorder.

Journal: Neuropsychiatric disease and treatment 20100101

Title: New insights in the management of antipsychotics in the treatment of schizophrenia in a patient with prolactinoma: a case report and review of the literature.

Journal: Case reports in medicine 20100101

Title: [Non-fatal paliperidone overdose: a case report].

Journal: Turk psikiyatri dergisi = Turkish journal of psychiatry 20100101

Title: [The review of acute risperidone poisoning].

Journal: Przeglad lekarski 20100101

Title: Simultaneous determination of risperidone and 9-hydroxyrisperidone enantiomers in human blood plasma by liquid chromatography with electrochemical detection.

Journal: Journal of pharmaceutical and biomedical analysis 20091205

Title: Impact of CYP2D6 genotype on steady-state serum concentrations of risperidone and 9-hydroxyrisperidone in patients using long-acting injectable risperidone.

Journal: Journal of clinical psychopharmacology 20091201

Title: Onset and persistence of antipsychotic response in patients with schizophrenia.

Journal: Journal of clinical psychopharmacology 20091201

Title: Management of schizophrenia with obesity, metabolic, and endocrinological disorders.

Journal: The Psychiatric clinics of North America 20091201

Title: Short- and long-term effects on prolactin of risperidone and olanzapine treatments in children and adolescents.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20091113

Title: Single- and multiple-dose pharmacokinetics and dose proportionality of the psychotropic agent paliperidone extended release.

Journal: Journal of clinical pharmacology 20091101

Title: Paliperidone for treatment of obsessive compulsive resistant symptoms in schizophrenia: a case report.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20091001

Title: No pharmacokinetic interaction between paliperidone extended-release tablets and trimethoprim in healthy subjects.

Journal: Human psychopharmacology 20091001

Title: Independent effect of paliperidone extended release on social functioning beyond its effect on positive and negative symptoms of schizophrenia: a mediation analysis.

Journal: Journal of clinical psychopharmacology 20091001

Title: The influence of hepatic impairment on the pharmacokinetics of paliperidone.

Journal: International journal of clinical pharmacology and therapeutics 20091001

Title: Determination of risperidone and 9-Hydroxyrisperidone using HPLC, in plasma of children and adolescents with emotional and behavioural disorders.

Journal: Biomedical chromatography : BMC 20090901

Title: Safety and tolerability of deltoid and gluteal injections of paliperidone palmitate in schizophrenia.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20090831

Title: Pharmacokinetics and efficacy of a direct switch from conventional depot to risperidone long-acting injection in Chinese patients with schizophrenic and schizoaffective disorders.

Journal: Psychiatry and clinical neurosciences 20090801

Title: Serum levels of risperidone and its metabolite, 9-hydroxyrisperidone: correlation between drug concentration and clinical response.

Journal: Therapeutic drug monitoring 20090801

Title: Paliperidone extended-release for schizophrenia: effects on symptoms and functioning in acutely ill patients with negative symptoms.

Journal: Schizophrenia research 20090801

Title: Iloperidone for schizophrenia: a review of the efficacy and safety profile for this newly commercialised second-generation antipsychotic.

Journal: International journal of clinical practice 20090801

Title: Impact of psychotic relapse definitions in assessing drug efficacy and costs: comparison of quetiapine XR, olanzapine and paliperidone ER.

Journal: Current medical research and opinion 20090701

Title: The effects of paroxetine on the pharmacokinetics of paliperidone extended-release tablets.

Journal: Pharmacopsychiatry 20090701

Title: Effects of the CYP2D6*10 alleles and co-medication with CYP2D6-dependent drugs on risperidone metabolism in patients with schizophrenia.

Journal: Human psychopharmacology 20090601

Title: Effects of CYP2D6 and CYP3A5 genotypes on the plasma concentrations of risperidone and 9-hydroxyrisperidone in Korean schizophrenic patients.

Journal: Journal of clinical psychopharmacology 20090601

Title: Paliperidone suppresses the development of the aggressive phenotype in a developmentally sensitive animal model of escalated aggression.

Journal: Psychopharmacology 20090501

Title: Use and safety of antipsychotic drugs during pregnancy.

Journal: Journal of psychiatric practice 20090501

Title: Secondary delusional parasitosis treated with paliperidone.

Journal: Clinical and experimental dermatology 20090401

Title: An agonist-antagonist interaction model for prolactin release following risperidone and paliperidone treatment.

Journal: Clinical pharmacology and therapeutics 20090401

Title: Unbound drug concentration in brain homogenate and cerebral spinal fluid at steady state as a surrogate for unbound concentration in brain interstitial fluid.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090401

Title: Sensitivity of older patients to antipsychotic motor side effects: a PET study examining potential mechanisms.

Journal: The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20090301

Title: Paliperidone in an adult patient with Asperger syndrome: case report.

Journal: Pharmacopsychiatry 20090301

Title: Expected clinical benefits of paliperidone extended-release formulation when compared with risperidone immediate-release.

Journal: Expert opinion on drug delivery 20090301

Title: Reliability, validity and ability to detect change of the clinician-rated Personal and Social Performance scale in patients with acute symptoms of schizophrenia.

Journal: Current medical research and opinion 20090201

Title: The recognition and treatment of pathological skin picking: a potential neurobiological underpinning of the efficacy of pharmacotherapy in impulse control disorders.

Journal: Psychiatry (Edgmont (Pa. : Township)) 20090201

Title: [Psychiatry].

Journal: Revue medicale suisse 20090114

Title: Practical guidelines for the use of new generation antipsychotic drugs (except clozapine) in adult individuals with intellectual disabilities.

Journal: Research in developmental disabilities 20090101

Title: Antipsychotic-induced hyperprolactinemia.

Journal: Pharmacotherapy 20090101

Title: Cost-effectiveness model comparing olanzapine and other oral atypical antipsychotics in the treatment of schizophrenia in the United States.

Journal: Cost effectiveness and resource allocation : C/E 20090101

Title: [The use of ixel in the treatment of depression in patients with chronic schizophrenia].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101

Title: Neuroleptic malignant syndrome associated with atypical antipsychotic drugs.

Journal: CNS drugs 20090101

Title: Population pharmacokinetics of intramuscular paliperidone palmitate in patients with schizophrenia: a novel once-monthly, long-acting formulation of an atypical antipsychotic.

Journal: Clinical pharmacokinetics 20090101

Title: Teratogenicity and hyperprolactinemia.

Journal: Indian journal of psychiatry 20090101

Title: Drugs associated with more suicidal ideations are also associated with more suicide attempts.

Journal: PloS one 20090101

Title: Galactorrhea associated with juvenile systemic lupus erythematosus: a review of the role of prolactin.

Journal: Pediatric rheumatology online journal 20090101

Title: Paliperidon mediated modification of cortical inhibition.

Journal: Neuro endocrinology letters 20090101

Title: Treatment of psychotic symptoms in bipolar disorder with aripiprazole monotherapy: a meta-analysis.

Journal: Annals of general psychiatry 20090101

Title: [Treatment with paliperidone extended-release tablets in a case of resistant undifferentiated schizophrenia: clinical improvement with 12 mg and evaluation through 3TRE scale].

Journal: Rivista di psichiatria 20090101

Title: Study of the complexation of risperidone and 9-hydroxyrisperidone with cyclodextrin hosts using affinity capillary electrophoresis and (1)H NMR spectroscopy.

Journal: Journal of chromatography. A 20081226

Title: Clinical significance of a CYP2D6 poor metabolizer--a patient with schizophrenia on risperidone treatment.

Journal: Therapeutic drug monitoring 20081201

Title: One-year clinical and economic consequences of oral atypical antipsychotics in the treatment of schizophrenia.

Journal: Current medical research and opinion 20081201

Title: What are the nursing implications when using paliperidone prolonged release for people with schizophrenia.

Journal: Journal of psychiatric and mental health nursing 20081201

Title: Apparent seizure and atrial fibrillation associated with paliperidone.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20081115

Title: Review: paliperidone reduces symptoms of schizophrenia and schizophrenia-like illness.

Journal: Evidence-based mental health 20081101

Title: Paliperidone as a mood stabilizer: a pre-frontal cortex synaptoneurosomal proteomics comparison with lithium and valproic acid after chronic treatment reveals similarities in protein expression.

Journal: Brain research 20081003

Title: ABCB1 polymorphisms influence steady-state plasma levels of 9-hydroxyrisperidone and risperidone active moiety.

Journal: Therapeutic drug monitoring 20081001

Title: Paliperidone extended-release for the treatment of schizophrenia.

Journal: Pharmacotherapy 20081001

Title: Antipsychotic drugs inhibit the function of breast cancer resistance protein.

Journal: Basic & clinical pharmacology & toxicology 20081001

Title: Risperidone long-acting injection: a review of its long term safety and efficacy.

Journal: Neuropsychiatric disease and treatment 20081001

Title: Direct and indirect effects of paliperidone extended-release tablets on negative symptoms of schizophrenia.

Journal: Neuropsychiatric disease and treatment 20081001

Title: Choreatic symptoms during and after treatment with paliperidone and escitalopram.

Journal: Pharmacopsychiatry 20080901

Title: Monthly administration of long-acting injectable risperidone and striatal dopamine D2 receptor occupancy for the management of schizophrenia.

Journal: The Journal of clinical psychiatry 20080801

Title: Paliperidone extended-release tablets in schizophrenia patients previously treated with risperidone.

Journal: International clinical psychopharmacology 20080701

Title: Validated LC-MS/MS methods for the determination of risperidone and the enantiomers of 9-hydroxyrisperidone in human plasma and urine.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080701

Title: Metabolism of atypical antipsychotics: involvement of cytochrome p450 enzymes and relevance for drug-drug interactions.

Journal: Current drug metabolism 20080601

Title: Hospitalization rates before and after initiation of paliperidone ER in patients with schizophrenia: results from open-label extensions of the US double-blind trials.

Journal: Current medical research and opinion 20080601

Title: Acute and long-term treatment of mania.

Journal: Dialogues in clinical neuroscience 20080601

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20080601

Title: Paliperidone for treatment of schizophrenia.

Journal: Schizophrenia bulletin 20080501

Title: Efficacy and tolerability of oral paliperidone extended-release tablets in the treatment of acute schizophrenia: pooled data from three 6-week, placebo-controlled studies.

Journal: The Journal of clinical psychiatry 20080501

Title: Paliperidone for schizophrenia.

Journal: The Cochrane database of systematic reviews 20080416

Title: Pharmacodynamic consequences of P-glycoprotein-dependent pharmacokinetics of risperidone and haloperidol in mice.

Journal: Behavioural brain research 20080409

Title: Dose-finding study of paliperidone ER based on striatal and extrastriatal dopamine D2 receptor occupancy in patients with schizophrenia.

Journal: Psychopharmacology 20080401

Title: Absorption, metabolism, and excretion of paliperidone, a new monoaminergic antagonist, in humans.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080401

Title: Paliperidone: An improvement over risperidone?

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080301

Title: Paliperidone for schizophrenia.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080301

Title: In vitro P-glycoprotein assays to predict the in vivo interactions of P-glycoprotein with drugs in the central nervous system.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080201

Title: Relationship between prolactin secretion, and plasma risperidone and 9-hydroxyrisperidone concentrations in adolescents with schizophreniform disorder.

Journal: Psychoneuroendocrinology 20080201

Title: Paliperidone-ER: first atypical antipsychotic with oral extended release formulation.

Journal: Expert review of neurotherapeutics 20080201

Title: Paliperidone extended-release tablets for the acute and maintenance treatment of schizophrenia.

Journal: Clinical therapeutics 20080201

Title: Atypical antipsychotic-induced metabolic side effects: insights from receptor-binding profiles.

Journal: Molecular psychiatry 20080101

Title: Efficacy and tolerability of second-generation antipsychotics in children and adolescents with schizophrenia.

Journal: Schizophrenia bulletin 20080101

Title: Effect of rifampin, an inducer of CYP3A and P-glycoprotein, on the pharmacokinetics of risperidone.

Journal: Journal of clinical pharmacology 20080101

Title: Safety and tolerability of oral paliperidone extended-release tablets in elderly patients with schizophrenia: a double-blind, placebo-controlled study with six-month open-label extension.

Journal: The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20080101

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20080101

Title: Functional polymorphism of the human multidrug resistance gene (MDR1) and polydipsia-hyponatremia in schizophrenia.

Journal: Neuromolecular medicine 20080101

Title: Costs and effects of paliperidone extended release compared with alternative oral antipsychotic agents in patients with schizophrenia in Greece: a cost effectiveness study.

Journal: Annals of general psychiatry 20080101

Title: Sleep disturbances in patients with schizophrenia : impact and effect of antipsychotics.

Journal: CNS drugs 20080101

Title: Upcoming agents for the treatment of schizophrenia: mechanism of action, efficacy and tolerability.

Journal: Drugs 20080101

Title: Medication adherence in schizophrenia: patient perspectives and the clinical utility of paliperidone ER.

Journal: Patient preference and adherence 20080101

Title: RP-HPLC Estimation of Risperidone in Tablet Dosage Forms.

Journal: Indian journal of pharmaceutical sciences 20080101

Title: Efficacy and safety of paliperidone extended-release tablets: results of a 6-week, randomized, placebo-controlled study.

Journal: Biological psychiatry 20071215

Title: Clinical implications of antipsychotic-induced hyperprolactinemia in patients with schizophrenia spectrum or bipolar spectrum disorders: recent developments and current perspectives.

Journal: Journal of clinical psychopharmacology 20071201

Title: Paliperidone: new drug. Just a metabolite of risperidone, a neuroleptic soon off-patent.

Journal: Prescrire international 20071201

Title: Paliperidone ER: a review of the clinical trial data.

Journal: Neuropsychiatric disease and treatment 20071201

Title: Pharmacogenetics of antipsychotic adverse effects: Case studies and a literature review for clinicians.

Journal: Neuropsychiatric disease and treatment 20071201

Title: Serum prolactin levels, plasma risperidone levels, polymorphism of cytochrome P450 2D6 and clinical response in patients with schizophrenia.

Journal: Journal of psychopharmacology (Oxford, England) 20071101

Title: The pharmacology and safety of paliperidone extended-release in the treatment of schizophrenia.

Journal: Expert opinion on drug safety 20071101

Title: Sensitive liquid chromatography/tandem mass spectrometry method for the simultaneous determination of olanzapine, risperidone, 9-hydroxyrisperidone, clozapine, haloperidol and ziprasidone in rat brain tissue.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071015

Title: Review and analysis of hospitalization costs associated with antipsychotic nonadherence in the treatment of schizophrenia in the United States.

Journal: Current medical research and opinion 20071001

Title: Paliperidone: a new extended-release oral atypical antipsychotic.

Journal: Expert opinion on pharmacotherapy 20071001

Title: Dopamine transporter polymorphisms and risperidone response in Chinese schizophrenia patients: an association study.

Journal: Pharmacogenomics 20071001

Title: Age and gender effects on olanzapine and risperidone plasma concentrations in children and adolescents.

Journal: Journal of child and adolescent psychopharmacology 20071001

Title: Analytical and semipreparative enantioseparation of 9-hydroxyrisperidone, the main metabolite of risperidone, using high-performance liquid chromatography and capillary electrophoresis. Validation and determination of enantiomeric purity.

Journal: Journal of chromatography. A 20070907

Title: Distinct electrophysiological effects of paliperidone and risperidone on the firing activity of rat serotonin and norepinephrine neurons.

Journal: Psychopharmacology 20070901

Title: Simultaneous determination of five antipsychotic drugs in rat plasma by high performance liquid chromatography with ultraviolet detection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070901

Title: Enantioselective analysis of the antipsychotic 9-hydroxyrisperidone, main metabolite of risperidone, by chiral capillary EKC using dual CDs.

Journal: Electrophoresis 20070801

Title: Efficacy, safety and early response of paliperidone extended-release tablets (paliperidone ER): results of a 6-week, randomized, placebo-controlled study.

Journal: Schizophrenia research 20070701

Title: Determination of risperidone and enantiomers of 9-hydroxyrisperidone in plasma by LC-MS/MS.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070601

Title: [Development and identifiability analysis of parent-metabolite pharmacokinetic model for risperidone and its main active metabolite 9-hydroxyrisperidone].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20070601

Title: Molecule of the month. Paliperidone.

Journal: Drug news & perspectives 20070601

Title: P-glycoprotein and cytochrome P450 3A4 involvement in risperidone transport using an in vitro Caco-2/TC7 model and an in vivo model.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20070509

Title: Simultaneous analysis of classical neuroleptics, atypical antipsychotics and their metabolites in human plasma.

Journal: Analytical and bioanalytical chemistry 20070501

Title: A study of genetic (CYP2D6 and ABCB1) and environmental (drug inhibitors and inducers) variables that may influence plasma risperidone levels.

Journal: Pharmacopsychiatry 20070501

Title: Lack of bioequivalence between generic risperidone oral solution and originator risperidone tablets.

Journal: International journal of clinical pharmacology and therapeutics 20070501

Title: Risperidone and paliperidone inhibit p-glycoprotein activity in vitro.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070401

Title: Population pharmacokinetics of risperidone and 9-hydroxyrisperidone in patients with acute episodes associated with bipolar I disorder.

Journal: Journal of pharmacokinetics and pharmacodynamics 20070401

Title: Paliperidone: quo vadis?

Journal: International journal of clinical practice 20070401

Title: Extended-release paliperidone: efficacy, safety and tolerability profile of a new atypical antipsychotic.

Journal: Drugs of today (Barcelona, Spain : 1998) 20070401

Title: Paliperidone (Invega) for schizophrenia.

Journal: The Medical letter on drugs and therapeutics 20070312

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20070301

Title: Treatment of schizophrenia with paliperidone extended-release tablets: a 6-week placebo-controlled trial.

Journal: Schizophrenia research 20070201

Title: Paliperidone extended-release tablets for prevention of symptom recurrence in patients with schizophrenia: a randomized, double-blind, placebo-controlled study.

Journal: Journal of clinical psychopharmacology 20070201

Title: Prolactin release in children treated with risperidone: impact and role of CYP2D6 metabolism.

Journal: Journal of clinical psychopharmacology 20070201

Title: Development of in situ ion selective sensors for dissolution.

Journal: Analytica chimica acta 20070102

Title: Maintenance therapy with once-monthly administration of long-acting injectable risperidone in patients with schizophrenia or schizoaffective disorder: a pilot study of an extended dosing interval.

Journal: Annals of general psychiatry 20070101

Title: Liquid chromatography/tandem mass spectrometry method for the simultaneous determination of olanzapine, risperidone, 9-hydroxyrisperidone, clozapine, haloperidol and ziprasidone in rat plasma.

Journal: Rapid communications in mass spectrometry : RCM 20070101

Title: Valproic acid improves psychotic agitation without influencing plasma risperidone levels in schizophrenic patients.

Journal: Pharmacopsychiatry 20070101

Title: Paliperidone extended release.

Journal: CNS drugs 20070101

Title: Clinical pharmacokinetics of atypical antipsychotics: a critical review of the relationship between plasma concentrations and clinical response.

Journal: Clinical pharmacokinetics 20070101

Title: New drugs: paliperidone, dasatinib, and decitabine.

Journal: Journal of the American Pharmacists Association : JAPhA 20070101

Title: Long-acting formulations of atypical antipsychotics: time to reconsider when to introduce depot antipsychotics.

Journal: CNS drugs 20070101

Title: Possible neuroleptic malignant syndrome associated with paliperidone.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20070101

Title: Forty years of antipsychotic Drug research--from haloperidol to paliperidone--with Dr. Paul Janssen.

Journal: Arzneimittel-Forschung 20070101

Title: Paliperidone: the evidence of its therapeutic value in schizophrenia.

Journal: Core evidence 20070101

Title: Prolactin elevation of the antipsychotic risperidone is predominantly related to its 9-hydroxy metabolite.

Journal: Human psychopharmacology 20061201

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20061201

Title: The complexity of active metabolites in therapeutic drug monitoring of psychotropic drugs.

Journal: Pharmacopsychiatry 20060701

Title: Risperidone in the treatment of psychotic depression.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20060601

Title: Risperidone in the treatment of bipolar mania.

Journal: Neuropsychiatric disease and treatment 20060601

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20060401

Title: Multiple dose pharmacokinetics of risperidone and 9-hydroxyrisperidone in Chinese female patients with schizophrenia.

Journal: Acta pharmacologica Sinica 20060301

Title: A PET study evaluating dopamine D2 receptor occupancy for long-acting injectable risperidone.

Journal: The American journal of psychiatry 20060301

Title: Liquid chromatography/tandem mass spectrometry method for simultaneous determination of risperidone and its active metabolite 9-hydroxyrisperidone in human plasma.

Journal: Rapid communications in mass spectrometry : RCM 20060101

Title: Dose-dependent interaction of paroxetine with risperidone in schizophrenic patients.

Journal: Journal of clinical psychopharmacology 20051201

Title: Delayed respiratory depression after risperidone overdose.

Journal: Anesthesia and analgesia 20051101

Title: Cytochrome P450 3A inhibitor itraconazole affects plasma concentrations of risperidone and 9-hydroxyrisperidone in schizophrenic patients.

Journal: Clinical pharmacology and therapeutics 20051101

Title: Risperidone half-life in a patient taking paroxetine -- a case report.

Journal: Pharmacopsychiatry 20050901

Title: D2 dopamine receptor occupancy, risperidone plasma level and extrapyramidal motor symptoms in previously drug-free schizophrenic patients.

Journal: International journal of clinical pharmacology and therapeutics 20050801

Title: Influence of age and gender on risperidone plasma concentrations.

Journal: Journal of psychopharmacology (Oxford, England) 20050701

Title: Effect of verapamil on pharmacokinetics and pharmacodynamics of risperidone: in vivo evidence of involvement of P-glycoprotein in risperidone disposition.

Journal: Clinical pharmacology and therapeutics 20050701

Title: Pharmacokinetics and D2 receptor occupancy of long-acting injectable risperidone (Risperdal Consta) in patients with schizophrenia.

Journal: The international journal of neuropsychopharmacology 20050301

Title: Risperidone and breast-feeding.

Journal: Journal of psychopharmacology (Oxford, England) 20050301

Title: Prediction of response to risperidone treatment with respect to plasma concencentrations of risperidone, catecholamine metabolites, and polymorphism of cytochrome P450 2D6.

Journal: International clinical psychopharmacology 20050301

Title: Serum concentrations of risperidone and 9-hydroxyrisperidone after administration of the long-acting injectable form of risperidone: evidence from a routine therapeutic drug monitoring service.

Journal: Therapeutic drug monitoring 20050201

Title: Interpreting serum risperidone concentrations.

Journal: Pharmacotherapy 20050201

Title: HPLC-DAD determination of plasma levels of the antipsychotic risperidone and its main metabolite for toxicological purposes.

Journal: Journal of separation science 20050201

Title: Advances in analytical toxicology: the current role of liquid chromatography-mass spectrometry in drug quantification in blood and oral fluid.

Journal: Analytical and bioanalytical chemistry 20050101

Title: The impact of P-glycoprotein on the disposition of drugs targeted for indications of the central nervous system: evaluation using the MDR1A/1B knockout mouse model.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050101

Title: The brain entry of risperidone and 9-hydroxyrisperidone is greatly limited by P-glycoprotein.

Journal: The international journal of neuropsychopharmacology 20041201

Title: Pharmacokinetics and tolerability of long-acting risperidone in schizophrenia.

Journal: Schizophrenia research 20040901

Title: A high-performance liquid chromatographic-atmospheric pressure chemical ionization-tandem mass spectrometric method for determination of risperidone and 9-hydroxyrisperidone in human plasma.

Journal: Journal of analytical toxicology 20040901

Title: The role of cytochrome P450 enzymes in the metabolism of risperidone and its clinical relevance for drug interactions.

Journal: Current drug targets 20040801

Title: Effects of various factors on steady-state plasma concentrations of risperidone and 9-hydroxyrisperidone: lack of impact of MDR-1 genotypes.

Journal: British journal of clinical pharmacology 20040501

Title: Quantification of risperidone and 9-hydroxyrisperidone in plasma and saliva from adult and pediatric patients by liquid chromatography-mass spectrometry.

Journal: Journal of chromatography. A 20040213

Title: Transfer of risperidone and 9-hydroxyrisperidone into human milk.

Journal: The Annals of pharmacotherapy 20040201

Title: Intra- and interindividual variations in steady-state plasma concentrations of risperidone and 9-hydroxyrisperidone in schizophrenic patients treated chronically with various doses of risperidone.

Journal: Therapeutic drug monitoring 20031201

Title: Lack of a pharmacokinetic interaction between mirtazapine and the newer antipsychotics clozapine, risperidone and olanzapine in patients with chronic schizophrenia.

Journal: Pharmacological research 20031001

Title: Effects of various CYP2D6 genotypes on the steady-state plasma concentrations of risperidone and its active metabolite, 9-hydroxyrisperidone, in Japanese patients with schizophrenia.

Journal: Therapeutic drug monitoring 20030601

Title: High-performance liquid chromatographic method with diode array detection to identify and quantify atypical antipsychotics and haloperidol in plasma after overdose.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030505

Title: Screening, library-assisted identification and validated quantification of fifteen neuroleptics and three of their metabolites in plasma by liquid chromatography/mass spectrometry with atmospheric pressure chemical ionization.

Journal: Journal of mass spectrometry : JMS 20030301

Title: Effects of CYP2D6 genotypes on plasma concentrations of risperidone and enantiomers of 9-hydroxyrisperidone in Japanese patients with schizophrenia.

Journal: Journal of clinical pharmacology 20030201

Title: Pharmacokinetic and safety assessments of concurrent administration of risperidone and donepezil.

Journal: Journal of clinical pharmacology 20030201

Title: Validated method for the determination of risperidone and 9-hydroxyrisperidone in human plasma by liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030115

Title: Determination of risperidone and 9-hydroxyrisperidone in human plasma by liquid chromatography: application to the evaluation of CYP2D6 drug interactions.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030105

Title: Pharmacokinetic and safety assessments of galantamine and risperidone after the two drugs are administered alone and together.

Journal: Journal of clinical pharmacology 20021201

Title: Optimizing dosing in atypical neuroleptic monotherapy.

Journal: Dialogues in clinical neuroscience 20021201

Title: A colloidal graphite-coated emitter for sheathless capillary electrophoresis/nanoelectrospray ionization mass spectrometry.

Journal: Analytical chemistry 20021015

Title: Prediction and assessment of extrapyramidal side effects induced by risperidone based on dopamine D(2) receptor occupancy.

Journal: Synapse (New York, N.Y.) 20021001

Title: Lack of correlation between the steady-state plasma concentrations of haloperidol and risperidone.

Journal: Journal of clinical pharmacology 20021001

Title: Simplified high-performance liquid chromatographic method for determination of risperidone and 9-hydroxyrisperidone in plasma after overdose.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020605

Title: Significant pharmacokinetic interaction between risperidone and carbamazepine: its relationship with CYP2D6 genotypes.

Journal: Psychopharmacology 20020601

Title: Comparison of prolactin concentrations between haloperidol and risperidone treatments in the same female patients with schizophrenia.

Journal: Psychopharmacology 20020601

Title: Long-term pharmacoclinical follow-up in schizophrenic patients treated with risperidone. Plasma and red blood cell concentrations of risperidone and its 9-hydroxymetabolite and their relationship to whole blood serotonin and tryptophan, plasma homovanillic acid, 5-hydroxyindoleacetic acid, dihydroxyphenylethyleneglycol and clinical evaluations.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20020601

Title: Cytochrome P450 2D6 deficiency and its clinical relevance in a patient treated with risperidone.

Journal: Pharmacopsychiatry 20020501

Title: In vivo and in vitro myocardial binding of risperidone and 9-hydroxyrisperidone.

Journal: Toxicology and applied pharmacology 20020415

Title: Brain, plasma and tissue pharmacokinetics of risperidone and 9-hydroxyrisperidone after separate oral administration to rats.

Journal: Psychopharmacology 20020201

Title: Risperidone and 9-hydroxyrisperidone concentrations are not dependent on age or creatinine clearance among elderly subjects.

Journal: Journal of geriatric psychiatry and neurology 20020101

Title: No effect of reboxetine on plasma concentrations of clozapine, risperidone, and their active metabolites.

Journal: Therapeutic drug monitoring 20011201

Title: Risperidone metabolism in relation to CYP2D6*10 allele in Korean schizophrenic patients.

Journal: European journal of clinical pharmacology 20011101

Title: Different enantioselective 9-hydroxylation of risperidone by the two human CYP2D6 and CYP3A4 enzymes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20011001

Title: Plasma concentrations of risperidone and 9-hydroxyrisperidone during combined treatment with paroxetine.

Journal: Therapeutic drug monitoring 20010601

Title: Relationship between plasma risperidone and 9-hydroxyrisperidone concentrations and clinical response in patients with schizophrenia.

Journal: Psychopharmacology 20010101

Title: Possible relationship between combined plasma concentrations of risperidone plus 9-hydroxyrisperidone and extrapyramidal symptoms. Preliminary study.

Journal: Neuropsychobiology 20010101

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Tags:130049-85-3 Molecular Formula|130049-85-3 MDL|130049-85-3 SMILES|130049-85-3 (R)-9-Hydroxy Risperidone