Home Amines 131410-48-5
131410-48-5,MFCD12912458
Catalog No.:AA00HSDQ

131410-48-5 | Gadolinium,[5,8-bis[(carboxy-kO)methyl]-11-[2-(methylamino)-2-(oxo-kO)ethyl]-3-(oxo-kO)-2,5,8,11-tetraazatridecan-13-oato(3-)-kN5,kN8,kN11,kO13]-

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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00HSDQ
Chemical Name:
Gadolinium,[5,8-bis[(carboxy-kO)methyl]-11-[2-(methylamino)-2-(oxo-kO)ethyl]-3-(oxo-kO)-2,5,8,11-tetraazatridecan-13-oato(3-)-kN5,kN8,kN11,kO13]-
CAS Number:
131410-48-5
Molecular Formula:
C16H26GdN5O8
Molecular Weight:
573.6563
MDL Number:
MFCD12912458
SMILES:
CNC(=O)CN(CC(=O)[O-])CCN(CC(=O)[O-])CCN(CC(=O)NC)CC(=O)[O-].[Gd+3]
Properties
Computed Properties
 
Complexity:
527  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
13  

Downstream Synthesis Route
10138-52-0   
H3DTPA-BMA 
  131410-48-5 

[1]InorganicChemistry,2011,vol.50,p.3471-3478

[1]InorganicChemistry,2011,vol.50,p.3471-3478

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Title: Contrast-enhanced three-dimensional MR angiography with an elliptical centric view for the evaluation of intracranial aneurysms.

Journal: European radiology 20070501

Title: The dogma that gadolinium contrast media are less nephrotoxic than iodine agents for X-ray angiography is a misconception.

Journal: Heart and vessels 20070501

Title: Toxicological assessment of gadolinium release from contrast media.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20070401

Title: Nephrogenic systemic fibrosis: risk factors and incidence estimation.

Journal: Radiology 20070401

Title: The potential of ferumoxytol nanoparticle magnetic resonance imaging, perfusion, and angiography in central nervous system malignancy: a pilot study.

Journal: Neurosurgery 20070401

Title: Cytotoxicity of iodinated and gadolinium-based contrast agents in renal tubular cells at angiographic concentrations: in vitro study.

Journal: Radiology 20070201

Title: Nephrogenic systemic fibrosis: a review of 6 cases temporally related to gadodiamide injection (omniscan).

Journal: Investigative radiology 20070201

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Title: Added value of rest to stress study for recognition of artifacts in perfusion cardiovascular magnetic resonance.

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Title: Contrast agents for hepatic MRI.

Journal: Cancer imaging : the official publication of the International Cancer Imaging Society 20070101

Title: Discrepancy between the dynamic computed tomography and T2 magnetic resonance perfusion imaging in brain tumors: a report of 2 cases.

Journal: Journal of computer assisted tomography 20070101

Title: Gadolinium contrast media are more nephrotoxic than iodine media. The importance of osmolality in direct renal artery injections.

Journal: European radiology 20061201

Title: Nephrogenic systemic fibrosis: A serious late adverse reaction to gadodiamide.

Journal: European radiology 20061201

Title: Effect on bone induction of using contrast media to reconstitute recombinant human bone morphogenetic protein-2 in an ectopic model in rats.

Journal: Journal of neurosurgery. Spine 20061101

Title: Diskography: infectious complications from a series of 12,634 cases.

Journal: AJNR. American journal of neuroradiology 20061001

Title: Enhancement effects of test injection with a small amount of MR contrast medium in the oral and maxillofacial region.

Journal: European journal of radiology 20060901

Title: Contrast-enhanced adenosine-stress magnetic resonance imaging--feasibility and practicability of a protocol for detection or exclusion of ischemic heart disease in an outpatient setting.

Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20060901

Title: Dialyzability of gadodiamide in hemodialysis patients.

Journal: Radiation medicine 20060701

Title: Safety of gadodiamide mixed with a small quantity of iohexol in patients with impaired renal function undergoing coronary angiography.

Journal: Heart and vessels 20060501

Title: Effect of contrast enhancement on the measurement of carotid arterial lumen and wall volume using MRI.

Journal: Journal of magnetic resonance imaging : JMRI 20060401

Title: Abdominal and iliac arterial stenoses: comparative double-blinded randomized study of diagnostic accuracy of 3D MR angiography with gadodiamide or gadopentetate dimeglumine.

Journal: Radiology 20060301

Title: Effects of gadopentetate dimeglumine and gadodiamide on serum calcium, magnesium, and creatinine measurements.

Journal: Journal of magnetic resonance imaging : JMRI 20060301

Title: Rat tumor response to the vascular-disrupting agent 5,6-dimethylxanthenone-4-acetic acid as measured by dynamic contrast-enhanced magnetic resonance imaging, plasma 5-hydroxyindoleacetic acid levels, and tumor necrosis.

Journal: Neoplasia (New York, N.Y.) 20060301

Title: Gadolinium-based contrast agents and nephrotoxicity in patients undergoing coronary artery procedures.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060201

Title: One-shot CT and MR arthrography of the shoulder with a mixture of iodinated and paramagnetic contrast agents using arthroscopy as a gold standard.

Journal: La Radiologia medica 20060201

Title: Bowel magnetic resonance imaging of pediatric patients with oral mannitol MRI compared to endoscopy and intestinal ultrasound.

Journal: European radiology 20060101

Title: Table-moving contrast-enhanced magnetic resonance angiography in the evaluation of lower extremity peripheral arterial bypass grafts.

Journal: JBR-BTR : organe de la Societe royale belge de radiologie (SRBR) = orgaan van de Koninklijke Belgische Vereniging voor Radiologie (KBVR) 20060101

Title: Comparative study of the physicochemical properties of six clinical low molecular weight gadolinium contrast agents.

Journal: Contrast media & molecular imaging 20060101

Title: Effects of ionic and non-ionic paramagnetic contrast media on brain bio-electric activity.

Journal: Neuroradiology 20051101

Title: Effect of vascular targeting agent in rat tumor model: dynamic contrast-enhanced versus diffusion-weighted MR imaging.

Journal: Radiology 20051101

Title: Salivary gland tumors at in vivo proton MR spectroscopy.

Journal: Radiology 20051101

Title: Gadodiamide-based coronary angiography in a patient with severe renal insufficiency.

Journal: Journal of interventional cardiology 20051001

Title: Comparison of Gd [DTPA-bis (2-aminoethoxy) ethane] polymeric contrast agent with gadodiamide injection for interstitial MR lymphography: experimental study with rabbits.

Journal: Journal of magnetic resonance imaging : JMRI 20050901

Title: Interference of gadolinium-containing contrast-enhancing agents with colorimetric calcium laboratory testing.

Journal: Investigative radiology 20050801

Title: Comparison of contrast-enhanced MRI with iodine-123 BMIPP for detection of myocardial damage in hypertrophic cardiomyopathy.

Journal: AJR. American journal of roentgenology 20050801

Title: Human comparative study of zinc and copper excretion via urine after administration of magnetic resonance imaging contrast agents.

Journal: Radiation medicine 20050801

Title: Magnetic resonance-guided percutaneous angioplasty of femoral and popliteal artery stenoses using real-time imaging and intra-arterial contrast-enhanced magnetic resonance angiography.

Journal: Investigative radiology 20050501

Title: Contrast-enhanced magnetic resonance angiography of the lower extremities: standard-dose vs. high-dose gadodiamide injection.

Journal: Journal of magnetic resonance imaging : JMRI 20050401

Title: Nuclear spin relaxation study of aqueous raffinose solution in the presence of a gadolinium contrast agent.

Journal: Magnetic resonance in chemistry : MRC 20050301

Title: Demonstration of cardiac involvement of sarcoidosis by contrast-enhanced multislice computed tomography and delayed-enhanced magnetic resonance imaging.

Journal: Journal of computer assisted tomography 20050101

Title: Spurious hypocalcemia after Omniscan- or OptiMARK-enhanced magnetic resonance imaging: an algorithm for minimizing a false-positive laboratory value.

Journal: Archives of pathology & laboratory medicine 20041001

Title: Measurement of serum calcium concentration after administration of gadoversetamide in dogs.

Journal: Radiology 20041001

Title: Renal artery stenting using gadodiamide arteriography in patients with baseline renal insufficiency.

Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20041001

Title: Gadolinium-based contrast media may be nephrotoxic even at approved doses.

Journal: European radiology 20040901

Title: Dynamic MR imaging in Tolosa-Hunt syndrome.

Journal: European journal of radiology 20040901

Title: Humeral avulsion of the posterior band of the inferior glenohumeral ligament: MR arthrography and clinical correlation in 17 patients.

Journal: AJR. American journal of roentgenology 20040801

Title: Transendocardial delivery of extracellular myocardial markers by using combination X-ray/MR fluoroscopic guidance: feasibility study in dogs.

Journal: Radiology 20040601

Title: Model for predicting the impact of gadolinium on plasma calcium measured by the o-cresolphthalein method.

Journal: Clinical chemistry 20040401

Title: Use of gadolinium as an intraarterial contrast agent for pediatric neuroendovascular procedures.

Journal: Journal of neurosurgery 20040201

Title: Myocardial perfusion imaging using OMNISCAN: a dose finding study for visual assessment of stress-induced regional perfusion abnormalities.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20040101

Title: [Diagnostic efficacy of gadodiamide-enhanced dynamic examination technique in comparison to conventional magnet resonance tomography in exacerbated chronic osteomyelitis].

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Title: Contrast use at low field: a review.

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Title: Cortical, medullary, and pelvocaliceal MR renography with and without diuretic modification.

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Title: Pseudohypocalcemia with MR imaging contrast agents: a cautionary tale.

Journal: Radiology 20030601

Title: Gadodiamide administration causes spurious hypocalcemia.

Journal: Radiology 20030601

Title: pH-sensitive paramagnetic liposomes for MRI: assessment of stability in blood.

Journal: Magnetic resonance imaging 20030601

Title: Effect of subcutaneous butylscopolamine administration in the reduction of peristaltic artifacts in 1.5-T MR fast abdominal examinations.

Journal: European radiology 20030201

Title: Atypical focal nodular hyperplasia of the liver: imaging features of nonspecific and liver-specific MR contrast agents.

Journal: AJR. American journal of roentgenology 20021201

Title: Clinical testing of high-spatial-resolution parametric contrast-enhanced MR imaging of the breast.

Journal: AJR. American journal of roentgenology 20021201

Title: Measurement of volumetric and vascular changes with dynamic contrast enhanced MRI for cancer therapy monitoring.

Journal: Technology in cancer research & treatment 20021201

Title: [Gadolinium in arteriography and interventional radiology: 39 patients].

Journal: Journal de radiologie 20021101

Title: Gadodiamide as an alternative contrast agent during angioplasty in patients with contraindications to iodinated media.

Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20021001

Title: Gadodiamide and gadopentetate dimeglumine in MRI versus spiral CT in the diagnosis of liver lesions.

Journal: Academic radiology 20020801

Title: Nephrotoxicity after renal angiography using iodine and gadolinium contrast media in pigs with renal damage.

Journal: Academic radiology 20020801

Title: Double-blind, efficacy evaluation of gadobenate dimeglumine, a gadolinium chelate with enhanced relaxivity, in malignant lesions of the brain.

Journal: Investigative radiology 20020501

Title: The effects of paramagnetic contrast agents on metabolite protons in aqueous solution.

Journal: Physics in medicine and biology 20020321

Title: Magnetic resonance imaging of inflammatory bowel disease: evaluation in a rabbit model.

Journal: Journal of magnetic resonance imaging : JMRI 20020201

Title: Identification of protein surfaces by NMR measurements with a pramagnetic Gd(III) chelate.

Journal: Journal of the American Chemical Society 20020123

Title: Comparison of intraarterial and IV gadolinium-enhanced MR angiography with digital subtraction angiography for the detection of renal artery stenosis in pigs.

Journal: AJR. American journal of roentgenology 20020101

Title: [Low-osmolar gadodiamide as alternative contrast agent for diagnostic angiography and angiographic interventions in patients with renal insufficiency].

Journal: RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 20020101

Title: [Gadodiamide and carbon dioxide as alternative contrast media in patients with chronic renal failure].

Journal: Medicina 20020101

Title: Contrast between scar and recurrent herniated disk on contrast-enhanced MR images.

Journal: AJNR. American journal of neuroradiology 20020101

Title: Volume correction for edema in single-volume proton MR spectroscopy of contrast-enhancing multiple sclerosis lesions.

Journal: Magnetic resonance in medicine 20010801

Title: Central nervous system: review of clinical use of contrast media.

Journal: Topics in magnetic resonance imaging : TMRI 20010801

Title: pH-sensitive paramagnetic liposomes as MRI contrast agents: in vitro feasibility studies.

Journal: Magnetic resonance imaging 20010601

Title: Assessment of myocardial perfusion in coronary artery disease by magnetic resonance: a comparison with positron emission tomography and coronary angiography.

Journal: Circulation 20010508

Title: Safety of CO(2)- and gadodiamide-enhanced angiography for the evaluation and percutaneous treatment of renal artery stenosis in patients with chronic renal insufficiency.

Journal: AJR. American journal of roentgenology 20010501

Title: The use of gadolinium chelates for X-ray digital subtraction angiography.

Journal: Investigative radiology 20010501

Title: Contrast agents in acute myocardial infarction.

Journal: Magma (New York, N.Y.) 20010501

Title: Cardiovascular effects caused by rapid administration of gadoversetamide injection in anesthetized dogs.

Journal: Investigative radiology 20010501

Title: Gadolinium arteriography complicated by acute pancreatitis and acute renal failure.

Journal: Journal of vascular and interventional radiology : JVIR 20010301

Title: A clinical comparison of the safety and efficacy of MultiHance (gadobenate dimeglumine) and Omniscan (Gadodiamide) in magnetic resonance imaging in patients with central nervous system pathology.

Journal: Investigative radiology 20010201

Title: Detection of intracranial metastases: a multicenter, intrapatient comparison of gadobenate dimeglumine-enhanced MRI with routinely used contrast agents at equal dosage.

Journal: Investigative radiology 20010201

Title: Contrast-enhanced MR imaging of experimental acute tubular necrosis.

Journal: Acta radiologica (Stockholm, Sweden : 1987) 20010101

Title: Neurotolerability of contrast agents in rats with brain ischemia induced by transient middle cerebral artery occlusion: EEG evaluation.

Journal: Investigative radiology 20010101

Title: Perfusion MR imaging in gliomas: comparison with histologic tumor grade.

Journal: Korean journal of radiology 20010101

Title: Neurotoxic potential of gadodiamide after injection into the lateral cerebral ventricle of rats.

Journal: AJNR. American journal of neuroradiology 19980901

Title: Acute cardiotoxicity of gadolinium-based contrast media: findings in the isolated rat heart.

Journal: Academic radiology 19970401

Title: Urine profiles and kidney histology after ionic and nonionic radiologic and magnetic resonance contrast media in rats with cisplatin nephropathy.

Journal: Academic radiology 19950801

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SDS
Tags:131410-48-5 Molecular Formula|131410-48-5 MDL|131410-48-5 SMILES|131410-48-5 Gadolinium,[5,8-bis[(carboxy-kO)methyl]-11-[2-(methylamino)-2-(oxo-kO)ethyl]-3-(oxo-kO)-2,5,8,11-tetraazatridecan-13-oato(3-)-kN5,kN8,kN11,kO13]-