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1326-12-1,MFCD00071453
Catalog No.:AA009AO2

1326-12-1 | THIOFLAVINE S

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100mg
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA009AO2
Chemical Name:
THIOFLAVINE S
CAS Number:
1326-12-1
Molecular Formula:
C17H19ClN2S
Molecular Weight:
318.8642
MDL Number:
MFCD00071453
SMILES:
CC1=CC2=C(C=C1)[N+](=C(S2)C3=CC=C(C=C3)N(C)C)C.[Cl-]
NSC Number:
11235
Properties
Computed Properties
 
Complexity:
325  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
3  
Rotatable Bond Count:
2  

Literature

Title: Hopeahainol A binds reversibly at the acetylcholinesterase (AChE) peripheral site and inhibits enzyme activity with a novel higher order concentration dependence.

Journal: Chemico-biological interactions 20161125

Title: Inhibition of human islet amyloid polypeptide or amylin aggregation by two manganese-salen derivatives.

Journal: European journal of pharmacology 20130505

Title: Surface chemistry at the nanometer scale influences insulin aggregation.

Journal: Colloids and surfaces. B, Biointerfaces 20121201

Title: Unzipping the role of chirality in nanoscale self-assembly of tripeptide hydrogels.

Journal: Nanoscale 20121107

Title: Influence of the valine zipper region on the structure and aggregation of the basic leucine zipper (bZIP) domain of activating transcription factor 5 (ATF5).

Journal: Molecular pharmaceutics 20121105

Title: The N-methylated peptide SEN304 powerfully inhibits Aβ(1-42) toxicity by perturbing oligomer formation.

Journal: Biochemistry 20121023

Title: The butter flavorant, diacetyl, exacerbates β-amyloid cytotoxicity.

Journal: Chemical research in toxicology 20121015

Title: Molecular rotors: what lies behind the high sensitivity of the thioflavin-T fluorescent marker.

Journal: Accounts of chemical research 20120918

Title: Effect of melatonin on α-synuclein self-assembly and cytotoxicity.

Journal: Neurobiology of aging 20120901

Title: Binding of the three-repeat domain of tau to phospholipid membranes induces an aggregated-like state of the protein.

Journal: Biochimica et biophysica acta 20120901

Title: Amyloid-like fibril formation by tachykinin neuropeptides and its relevance to amyloid β-protein aggregation and toxicity.

Journal: Cell biochemistry and biophysics 20120901

Title: Cross-seeding effects of amyloid β-protein and α-synuclein.

Journal: Journal of neurochemistry 20120901

Title: Efficient access to highly pure β-amyloid peptide by optimized solid-phase synthesis.

Journal: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20120901

Title: Characterization of semisynthetic and naturally Nα-acetylated α-synuclein in vitro and in intact cells: implications for aggregation and cellular properties of α-synuclein.

Journal: The Journal of biological chemistry 20120817

Title: Interaction between amyloid-β pathology and cortical functional columnar organization.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120815

Title: Short polyglutamine peptide forms a high-affinity binding site for thioflavin-T at the N-terminus.

Journal: Organic & biomolecular chemistry 20120814

Title: Mutant p53 aggregates into prion-like amyloid oligomers and fibrils: implications for cancer.

Journal: The Journal of biological chemistry 20120810

Title: Inhibitory effect of curcumin on the Al(III)-induced Aβ₄₂ aggregation and neurotoxicity in vitro.

Journal: Biochimica et biophysica acta 20120801

Title: Anti-amyloidogenic effects of soybean isoflavones in vitro: Fluorescence spectroscopy demonstrating direct binding to Aβ monomers, oligomers and fibrils.

Journal: Biochimica et biophysica acta 20120801

Title: Ligand electronic properties modulate tau filament binding site density.

Journal: Biophysical chemistry 20120801

Title: PEGylated nanoparticles bind to and alter amyloid-beta peptide conformation: toward engineering of functional nanomedicines for Alzheimer's disease.

Journal: ACS nano 20120724

Title: Biocompatibility of mannan nanogel--safe interaction with plasma proteins.

Journal: Biochimica et biophysica acta 20120701

Title: Dissecting the role of disulfide bonds on the amyloid formation of insulin.

Journal: Biochemical and biophysical research communications 20120629

Title: Separation and detection of individual Aβ aggregates by capillary electrophoresis with laser-induced fluorescence detection.

Journal: Analytical biochemistry 20120615

Title: Fluorescent 2-styrylpyridazin-3(2H)-one derivatives as probes targeting amyloid-beta plaques in Alzheimer's disease.

Journal: Bioorganic & medicinal chemistry letters 20120615

Title: D-Ser-containing humanin shows promotion of fibril formation.

Journal: Amino acids 20120601

Title: Naphthoquinone-tyrptophan reduces neurotoxic Aβ*56 levels and improves cognition in Alzheimer's disease animal model.

Journal: Neurobiology of disease 20120601

Title: A new trend in the experimental methodology for the analysis of the thioflavin T binding to amyloid fibrils.

Journal: Molecular neurobiology 20120601

Title: Ultrafast molecular rotor: an efficient sensor for premelting of natural DNA.

Journal: Chemical communications (Cambridge, England) 20120528

Title: An FT-IR study on packing defects in mixed β-aggregates of poly(L-glutamic acid) and poly(D-glutamic acid): a high-pressure rescue from a kinetic trap.

Journal: The journal of physical chemistry. B 20120503

Title: Trifluoroethanol and acetonitrile induced formation of the molten globule states and aggregates of cellulase.

Journal: International journal of biological macromolecules 20120501

Title: Optimization of potent hepatitis C virus NS3 helicase inhibitors isolated from the yellow dyes thioflavine S and primuline.

Journal: Journal of medicinal chemistry 20120412

Title: Using graphene oxide high near-infrared absorbance for photothermal treatment of Alzheimer's disease.

Journal: Advanced materials (Deerfield Beach, Fla.) 20120403

Title: Modulation of pathway of insulin fibrillation by a small molecule helix inducer 2,2,2-trifluoroethanol.

Journal: Colloids and surfaces. B, Biointerfaces 20120401

Title: Molecular imaging of amyloidosis: will the heart be the next target after the brain?

Journal: Current cardiology reports 20120401

Title: Hexafluoroisopropanol induces self-assembly of β-amyloid peptides into highly ordered nanostructures.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20120401

Title: Identification and characterization of an aβ oligomer precipitating peptide that may be useful to explore gene therapeutic approaches to Alzheimer disease.

Journal: Rejuvenation research 20120401

Title: Detection of α-synuclein aggregates by fluorescence microscopy.

Journal: Rejuvenation research 20120401

Title: Conformational changes during amyloid fibril formation of pancreatic thiol proteinase inhibitor: effect of copper and zinc.

Journal: Molecular biology reports 20120301

Title: Self assembly of human septin 2 into amyloid filaments.

Journal: Biochimie 20120301

Title: Morin hydrate inhibits amyloid formation by islet amyloid polypeptide and disaggregates amyloid fibers.

Journal: Protein science : a publication of the Protein Society 20120301

Title: Interaction of thioflavin T with amyloid fibrils: fluorescence quantum yield of bound dye.

Journal: The journal of physical chemistry. B 20120301

Title: Early detection of insulin fibrillation: a fluorescence lifetime assay to probe the pre-fibrillar regime.

Journal: Chemical communications (Cambridge, England) 20120227

Title: Role of the helical structure of the N-terminal region of Plasmodium falciparum merozoite surface protein 2 in fibril formation and membrane interaction.

Journal: Biochemistry 20120221

Title: Inhibiting effect of α(s1)-casein on Aβ(1-40) fibrillogenesis.

Journal: Biochimica et biophysica acta 20120201

Title: The effect of nanoparticles on amyloid aggregation depends on the protein stability and intrinsic aggregation rate.

Journal: Langmuir : the ACS journal of surfaces and colloids 20120124

Title: Aβ(39-42) modulates Aβ oligomerization but not fibril formation.

Journal: Biochemistry 20120110

Title: Existence of different structural intermediates and aggregates on the folding pathway of ovalbumin.

Journal: Journal of fluorescence 20120101

Title: A screening tool for therapeutic monoclonal antibodies: Identifying the most stable protein and its best formulation based on thioflavin T binding.

Journal: Biotechnology journal 20120101

Title: Inhibition of amyloid peptide fragment Aβ25-35 fibrillogenesis and toxicity by N-terminal β-amino acid-containing esapeptides: is taurine moiety essential for in vivo effects?

Journal: Chemical biology & drug design 20120101

Title: Prion protein polymerisation triggered by manganese-generated prion protein seeds.

Journal: Journal of neurochemistry 20120101

Title: Characterization, amyloid formation, and immobilization of a novel SGNH hydrolase from Listeria innocua 11262.

Journal: International journal of biological macromolecules 20120101

Title: Interference of low-molecular substances with the thioflavin-T fluorescence assay of amyloid fibrils.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20120101

Title: Solid-state NMR reveals differences in the packing arrangements of peptide aggregates derived from the aortic amyloid polypeptide medin.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20120101

Title: Contrasting protective effects of cannabinoids against oxidative stress and amyloid-β evoked neurotoxicity in vitro.

Journal: Neurotoxicology 20120101

Title: SDS can be utilized as an amyloid inducer: a case study on diverse proteins.

Journal: PloS one 20120101

Title: Analyzing thioflavin T binding to amyloid fibrils by an equilibrium microdialysis-based technique.

Journal: PloS one 20120101

Title: Insights into the disparate action of osmolytes and macromolecular crowders on amyloid formation.

Journal: Prion 20120101

Title: Y145Stop is sufficient to induce de novo generation prions using protein misfolding cyclic amplification.

Journal: Prion 20120101

Title: Inhibition of aggregation of amyloid β42 by arginine-containing small compounds.

Journal: Bioscience, biotechnology, and biochemistry 20120101

Title: Establishing the links between Aβ aggregation and cytotoxicity in vitro using biophysical approaches.

Journal: Methods in molecular biology (Clifton, N.J.) 20120101

Title: Analysis of S100 oligomers and amyloids.

Journal: Methods in molecular biology (Clifton, N.J.) 20120101

Title: S100A8/A9 amyloidosis in the ageing prostate: relating ex vivo and in vitro studies.

Journal: Methods in molecular biology (Clifton, N.J.) 20120101

Title: Histological staining of amyloid and pre-amyloid peptides and proteins in mouse tissue.

Journal: Methods in molecular biology (Clifton, N.J.) 20120101

Title: The contrasting effect of macromolecular crowding on amyloid fibril formation.

Journal: PloS one 20120101

Title: Fibrillation of hen egg white lysozyme triggers reduction of copper(II).

Journal: International journal of biological macromolecules 20120101

Title: Doped diamond-like carbon coatings for surgical instruments reduce protein and prion-amyloid biofouling and improve subsequent cleaning.

Journal: Biofouling 20120101

Title: Fibril-forming motifs are essential and sufficient for the fibrillization of human Tau.

Journal: PloS one 20120101

Title: Synthesis and in vitro evaluation of fluorinated styryl benzazoles as amyloid-probes.

Journal: Bioorganic & medicinal chemistry 20111215

Title: Testing the therapeutic potential of doxycycline in a Drosophila melanogaster model of Alzheimer disease.

Journal: The Journal of biological chemistry 20111202

Title: Prefibrillar aggregates of yeast prion Sup35NM and its variant are toxic to mammalian cells.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20111201

Title: Dual conformation of H2H3 domain of prion protein in mammalian cells.

Journal: The Journal of biological chemistry 20111118

Title: A safe, blood-brain barrier permeable triphenylmethane dye inhibits amyloid-β neurotoxicity by generating nontoxic aggregates.

Journal: ACS chemical neuroscience 20111116

Title: Sensory network dysfunction, behavioral impairments, and their reversibility in an Alzheimer's β-amyloidosis mouse model.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20111102

Title: Role of oligomers in the amyloidogenesis of primary cutaneous amyloidosis.

Journal: Journal of the American Academy of Dermatology 20111101

Title: Inflammation protein SAA2.2 spontaneously forms marginally stable amyloid fibrils at physiological temperature.

Journal: Biochemistry 20111101

Title: Oligonucleotide-based label-free Hg2+ assay with a monomer-excimer fluorescence switch.

Journal: The Analyst 20111021

Title: Thioflavin T forms a non-fluorescent complex with α-helical poly-L-glutamic acid.

Journal: Chemical communications (Cambridge, England) 20111014

Title: Crocetin inhibits beta-amyloid fibrillization and stabilizes beta-amyloid oligomers.

Journal: Biochemical and biophysical research communications 20111014

Title: Interaction of thioflavin T with amyloid fibrils: stoichiometry and affinity of dye binding, absorption spectra of bound dye.

Journal: The journal of physical chemistry. B 20111006

Title: Nanotechnologies for Alzheimer's disease: diagnosis, therapy, and safety issues.

Journal: Nanomedicine : nanotechnology, biology, and medicine 20111001

Title: Resolution of localized small molecule-Aβ interactions by deep-ultraviolet resonance Raman spectroscopy.

Journal: Biophysical chemistry 20111001

Title: A novel mutation in transforming growth factor-beta induced protein (TGFβIp) reveals secondary structure perturbation in lattice corneal dystrophy.

Journal: The British journal of ophthalmology 20111001

Title: Synthesis and evaluation of ferrocenoyl pentapeptide (Fc-KLVFF) as an inhibitor of Alzheimer's Aβ₁-₄₂ fibril formation in vitro.

Journal: Bioorganic & medicinal chemistry letters 20111001

Title: Cucurbit[n]uril based supramolecular assemblies: tunable physico-chemical properties and their prospects.

Journal: Chemical communications (Cambridge, England) 20110928

Title: Designed hairpin peptides interfere with amyloidogenesis pathways: fibril formation and cytotoxicity inhibition, interception of the preamyloid state.

Journal: Biochemistry 20110927

Title: Inhibition of amyloid β aggregation and cytotoxicity by photodegradation using a designed fullerene derivative.

Journal: Chemistry, an Asian journal 20110905

Title: A standardized and biocompatible preparation of aggregate-free amyloid beta peptide for biophysical and biological studies of Alzheimer's disease.

Journal: Protein engineering, design & selection : PEDS 20110901

Title: Chiral superstructures of insulin amyloid fibrils.

Journal: Chirality 20110901

Title: Ligand polarizability contributes to tau fibril binding affinity.

Journal: Bioorganic & medicinal chemistry 20110901

Title: Modeling the nonradiative decay rate of electronically excited thioflavin T.

Journal: The journal of physical chemistry. A 20110804

Title: Hybrid hydrogels self-assembled from graft copolymers containing complementary β-sheets as hydroxyapatite nucleation scaffolds.

Journal: Biomaterials 20110801

Title: Targeting vascular amyloid in arterioles of Alzheimer disease transgenic mice with amyloid β protein antibody-coated nanoparticles.

Journal: Journal of neuropathology and experimental neurology 20110801

Title: Mechanism of amyloid β-protein aggregation mediated by GM1 ganglioside clusters.

Journal: Biochemistry 20110726

Title: Kinetic characterization of amyloid-beta 1-42 aggregation with a multimethodological approach.

Journal: Analytical biochemistry 20110715

Title: Probing the mechanism of insulin aggregation during agitation.

Journal: International journal of pharmaceutics 20110715

Title: Hexafluoroisopropanol induces amyloid fibrils of islet amyloid polypeptide by enhancing both hydrophobic and electrostatic interactions.

Journal: The Journal of biological chemistry 20110708

Title: Novel cell- and tissue-based assays for detecting misfolded and aggregated protein accumulation within aggresomes and inclusion bodies.

Journal: Cell biochemistry and biophysics 20110701

Title: Zinc, copper, and carnosine attenuate neurotoxicity of prion fragment PrP106-126.

Journal: Metallomics : integrated biometal science 20110701

Title: Acetonitrile can promote formation of different structural intermediate states on aggregation pathway of immunoglobulin G from human and bovine.

Journal: International journal of biological macromolecules 20110701

Title: The effect of red pigment on the amyloidization of yeast proteins.

Journal: Yeast (Chichester, England) 20110701

Title: Protein L-isoaspartyl O-methyltransferase inhibits amyloid beta fibrillogenesis in vitro.

Journal: Die Pharmazie 20110701

Title: A nano-confined charged layer defies the principle of electrostatic interaction.

Journal: Chemical communications (Cambridge, England) 20110628

Title: Pressure effect on the nonradiative process of thioflavin-T.

Journal: The journal of physical chemistry. A 20110623

Title: Study of thioflavin-T immobilized in porous silicon and the effect of different organic vapors on the fluorescence lifetime.

Journal: Langmuir : the ACS journal of surfaces and colloids 20110621

Title: Seed-dependent deposition behavior of Aβ peptides studied with wireless quartz-crystal-microbalance biosensor.

Journal: Analytical chemistry 20110615

Title: Binding modes of thioflavin T molecules to prion peptide assemblies identified by using scanning tunneling microscopy.

Journal: ACS chemical neuroscience 20110615

Title: Novel fluorescent trimethine cyanine dye 7519 for amyloid fibril inhibition assay.

Journal: Biotechnic & histochemistry : official publication of the Biological Stain Commission 20110601

Title: Nonnative aggregation of an IgG1 antibody in acidic conditions, part 2: nucleation and growth kinetics with competing growth mechanisms.

Journal: Journal of pharmaceutical sciences 20110601

Title: Nonnative aggregation of an IgG1 antibody in acidic conditions: part 1. Unfolding, colloidal interactions, and formation of high-molecular-weight aggregates.

Journal: Journal of pharmaceutical sciences 20110601

Title: Insight into amyloid structure using chemical probes.

Journal: Chemical biology & drug design 20110601

Title: Design and evaluation of a 6-mer amyloid-beta protein derived phage display library for molecular targeting of amyloid plaques in Alzheimer's disease: Comparison with two cyclic heptapeptides derived from a randomized phage display library.

Journal: Peptides 20110601

Title: Coumarin 6 and 1,6-diphenyl-1,3,5-hexatriene (DPH) as fluorescent probes to monitor protein aggregation.

Journal: The Analyst 20110521

Title: Rhodanine and thiohydantoin derivatives for detecting tau pathology in Alzheimer's brains.

Journal: ACS chemical neuroscience 20110518

Title: Influence of protein hydrolysis on the growth kinetics of β-lg fibrils.

Journal: Langmuir : the ACS journal of surfaces and colloids 20110517

Title: The Osaka FAD mutation E22Δ leads to the formation of a previously unknown type of amyloid β fibrils and modulates Aβ neurotoxicity.

Journal: Journal of molecular biology 20110513

Title: Monitoring the aggregation processes of amyloid-β using a spin-labeled, fluorescent nitroxyl radical.

Journal: Chemical communications (Cambridge, England) 20110507

Title: Interactions of Npc1 and amyloid accumulation/deposition in the APP/PS1 mouse model of Alzheimer's.

Journal: Journal of applied genetics 20110501

Title: High ability of apolipoprotein E4 to stabilize amyloid-β peptide oligomers, the pathological entities responsible for Alzheimer's disease.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110501

Title: Cerebral amyloid angiopathy in streptozotocin rat model of sporadic Alzheimer's disease: a long-term follow up study.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20110501

Title: Sequence-independent control of peptide conformation in liposomal vaccines for targeting protein misfolding diseases.

Journal: The Journal of biological chemistry 20110422

Title: A modified protocol to prepare seed-free starting solutions of amyloid-β (Aβ)₁₋₄₀ and Aβ₁₋₄₂ from the corresponding depsipeptides.

Journal: Analytical biochemistry 20110415

Title: Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan.

Journal: Nature 20110414

Title: Biflavonoids are superior to monoflavonoids in inhibiting amyloid-β toxicity and fibrillogenesis via accumulation of nontoxic oligomer-like structures.

Journal: Biochemistry 20110405

Title: Heparin binds 8 kDa gelsolin cross-β-sheet oligomers and accelerates amyloidogenesis by hastening fibril extension.

Journal: Biochemistry 20110405

Title: Spectroscopic characterization of diverse amyloid fibrils in vitro by the fluorescent dye Nile red.

Journal: Molecular bioSystems 20110401

Title: Bovine Serum Albumin protofibril-like aggregates formation: solo but not simple mechanism.

Journal: Archives of biochemistry and biophysics 20110401

Title: The effect of tachykinin neuropeptides on amyloid β aggregation.

Journal: Biochemical and biophysical research communications 20110401

Title: A new look at old compounds.

Journal: Aging 20110401

Title: Temperature dependence of the fluorescence properties of thioflavin-T in propanol, a glass-forming liquid.

Journal: The journal of physical chemistry. A 20110331

Title: Amyloid fibrils formation of concanavalin A at basic pH.

Journal: The journal of physical chemistry. B 20110331

Title: The Japanese mutant Aβ (ΔE22-Aβ(1-39)) forms fibrils instantaneously, with low-thioflavin T fluorescence: seeding of wild-type Aβ(1-40) into atypical fibrils by ΔE22-Aβ(1-39).

Journal: Biochemistry 20110329

Title: Destruction of amyloid fibrils of keratoepithelin peptides by laser irradiation coupled with amyloid-specific thioflavin T.

Journal: The Journal of biological chemistry 20110325

Title: Detecting the early onset of shear-induced fibril formation of insulin in situ.

Journal: The journal of physical chemistry. B 20110324

Title: Structural evolution of Iowa mutant β-amyloid fibrils from polymorphic to homogeneous states under repeated seeded growth.

Journal: Journal of the American Chemical Society 20110323

Title: Electrochemical detection of interaction between Thioflavin T and acetylcholinesterase.

Journal: The Analyst 20110321

Title: On the origin of the stronger binding of PIB over thioflavin T to protofibrils of the Alzheimer amyloid-β peptide: a molecular dynamics study.

Journal: Biophysical journal 20110302

Title: Characterization of the non-fibrillar α-synuclein oligomers.

Journal: Protein and peptide letters 20110301

Title: Use of yeast as a system to study amyloid toxicity.

Journal: Methods (San Diego, Calif.) 20110301

Title: Studying the effects of chaperones on amyloid fibril formation.

Journal: Methods (San Diego, Calif.) 20110301

Title: Assays for studying nucleated aggregation of polyglutamine proteins.

Journal: Methods (San Diego, Calif.) 20110301

Title: Both plant and animal LEA proteins act as kinetic stabilisers of polyglutamine-dependent protein aggregation.

Journal: FEBS letters 20110218

Title: Evaluation of aluminium, manganese, copper and selenium effects on human islets amyloid polypeptide hormone aggregation.

Journal: Pakistan journal of biological sciences : PJBS 20110215

Title: The role of the C-terminus of human α-synuclein: intra-disulfide bonds between the C-terminus and other regions stabilize non-fibrillar monomeric isomers.

Journal: FEBS letters 20110204

Title: Stereospecific interactions are necessary for Alzheimer disease amyloid-β toxicity.

Journal: Neurobiology of aging 20110201

Title: Ultrasensitive human prion detection in cerebrospinal fluid by real-time quaking-induced conversion.

Journal: Nature medicine 20110201

Title: Expression of human FUS/TLS in yeast leads to protein aggregation and cytotoxicity, recapitulating key features of FUS proteinopathy.

Journal: Protein & cell 20110201

Title: Synthesis and biophysical evaluation of arylhydrazono-1H-2-indolinones as β-amyloid aggregation inhibitors.

Journal: European journal of medicinal chemistry 20110101

Title: Curcuminoid binds to amyloid-β1-42 oligomer and fibril.

Journal: Journal of Alzheimer's disease : JAD 20110101

Title: The regulatory subunit of PKA-I remains partially structured and undergoes β-aggregation upon thermal denaturation.

Journal: PloS one 20110101

Title: A role for amyloid in cell aggregation and biofilm formation.

Journal: PloS one 20110101

Title: Calcium ions promote formation of amyloid β-peptide (1-40) oligomers causally implicated in neuronal toxicity of Alzheimer's disease.

Journal: PloS one 20110101

Title: Non-esterified fatty acids generate distinct low-molecular weight amyloid-β (Aβ42) oligomers along pathway different from fibril formation.

Journal: PloS one 20110101

Title: Conformational stability and aggregation of therapeutic monoclonal antibodies studied with ANS and Thioflavin T binding.

Journal: mAbs 20110101

Title: Diagnostics for amyloid fibril formation: where to begin?

Journal: Methods in molecular biology (Clifton, N.J.) 20110101

Title: Lack of LDL receptor enhances amyloid deposition and decreases glial response in an Alzheimer's disease mouse model.

Journal: PloS one 20110101

Title: Human apolipoprotein A-I-derived amyloid: its association with atherosclerosis.

Journal: PloS one 20110101

Title: Molecular interaction of TPPP with PrP antagonized the CytoPrP-induced disruption of microtubule structures and cytotoxicity.

Journal: PloS one 20110101

Title: The mechanism of enhanced insulin amyloid fibril formation by NaCl is better explained by a conformational change model.

Journal: PloS one 20110101

Title: [The effect of red pigment of Saccharomyces cerevisiae on insulin fibril formation in vitro].

Journal: Tsitologiia 20110101

Title: Proline periodicity modulates the self-assembly properties of elastin-like polypeptides.

Journal: The Journal of biological chemistry 20101217

Title: Comparative effects of pH and ionic strength on protein-protein interactions, unfolding, and aggregation for IgG1 antibodies.

Journal: Journal of pharmaceutical sciences 20101201

Title: The kinetic parameters and energy cost of the Hsp70 chaperone as a polypeptide unfoldase.

Journal: Nature chemical biology 20101201

Title: Interactions between amyloidophilic dyes and their relevance to studies of amyloid inhibitors.

Journal: Biophysical journal 20101117

Title: Synthesis and evaluation of stilbene derivatives as a potential imaging agent of amyloid plaques.

Journal: Bioorganic & medicinal chemistry 20101115

Title: Amyloid-binding small molecules efficiently block SEVI (semen-derived enhancer of virus infection)- and semen-mediated enhancement of HIV-1 infection.

Journal: The Journal of biological chemistry 20101112

Title: Protective effects of galantamine against Abeta-induced PC12 cell apoptosis by preventing mitochondrial dysfunction and endoplasmic reticulum stress.

Journal: Neurochemistry international 20101101

Title: Granular and lattice deposits in corneal dystrophy caused by R124C mutation of TGFBIp.

Journal: Cornea 20101101

Title: Attenuated antiaggregation effects of magnetite nanoparticles in cerebrospinal fluid of people with Alzheimer's disease.

Journal: Molecular bioSystems 20101101

Title: Reduction of hippocampal N-acetyl aspartate level in aged APP(Swe)/PS1(dE9) transgenic mice is associated with degeneration of CA3 pyramidal neurons.

Journal: Journal of neuroscience research 20101101

Title: I32E and V36K double mutation in beta2-sheet abrogates amyloid beta peptide toxicity.

Journal: Indian journal of experimental biology 20101101

Title: Amyloid-binding small molecule reduces HIV infection.

Journal: Future medicinal chemistry 20101101

Title: Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio.

Journal: The EMBO journal 20101006

Title: Fibrillation of alpha-lactalbumin: effect of crocin and safranal, two natural small molecules from Crocus sativus.

Journal: Biopolymers 20101001

Title: Highly sensitive amyloid detection enabled by thioflavin T dimers.

Journal: Molecular bioSystems 20101001

Title: Isolation of short peptide fragments from alpha-synuclein fibril core identifies a residue important for fibril nucleation: a possible implication for diagnostic applications.

Journal: Biochimica et biophysica acta 20101001

Title: Amyloid formation and disaggregation of α-synuclein and its tandem repeat (α-TR).

Journal: Biochemical and biophysical research communications 20101001

Title: The flavanol (-)-epigallocatechin 3-gallate inhibits amyloid formation by islet amyloid polypeptide, disaggregates amyloid fibrils, and protects cultured cells against IAPP-induced toxicity.

Journal: Biochemistry 20100921

Title: Molecular basis of inhibition of substrate hydrolysis by a ligand bound to the peripheral site of acetylcholinesterase.

Journal: Chemico-biological interactions 20100906

Title: Self-assembling pathway of HiApp fibrils within lipid bilayers.

Journal: Chembiochem : a European journal of chemical biology 20100903

Title: Quantifying prefibrillar amyloids in vitro by using a 'thioflavin-like' spectroscopic method.

Journal: Chembiochem : a European journal of chemical biology 20100903

Title: Alzheimer's disease: spect and pet tracers for beta-amyloid imaging.

Journal: Current Alzheimer research 20100901

Title: A beta-amino acid modified heptapeptide containing a designed recognition element disrupts fibrillization of the amyloid beta-peptide.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20100901

Title: Charge transfer process determines ultrafast excited state deactivation of thioflavin T in low-viscosity solvents.

Journal: The journal of physical chemistry. A 20100819

Title: Identifying the bond responsible for the fluorescence modulation in an amyloid fibril sensor.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20100809

Title: The amyloid fibrils of the constant domain of immunoglobulin light chain.

Journal: FEBS letters 20100804

Title: L-Arginine reduces thioflavin T fluorescence but not fibrillation of bovine serum albumin.

Journal: Amino acids 20100801

Title: beta-Sheet aggregation of kisspeptin-10 is stimulated by heparin but inhibited by amphiphiles.

Journal: Biopolymers 20100801

Title: Abeta20-29 peptide blocking apoE/Abeta interaction reduces full-length Abeta42/40 fibril formation and cytotoxicity in vitro.

Journal: Neuropeptides 20100801

Title: Activation of phospholipase A2 by 1-palmitoyl-2-(9'-oxo-nonanoyl)-sn-glycero-3-phosphocholine in vitro.

Journal: Biochimica et biophysica acta 20100801

Title: Resveratrol selectively remodels soluble oligomers and fibrils of amyloid Abeta into off-pathway conformers.

Journal: The Journal of biological chemistry 20100730

Title: The dissociated form of kappa-casein is the precursor to its amyloid fibril formation.

Journal: The Biochemical journal 20100715

Title: Substoichiometric inhibition of Abeta(1-40) aggregation by a tandem Abeta(40-1-Gly8-1-40) peptide.

Journal: Biochemical and biophysical research communications 20100702

Title: Domain a' of protein disulfide isomerase plays key role in inhibiting alpha-synuclein fibril formation.

Journal: Cell stress & chaperones 20100701

Title: Molecular mechanism of Thioflavin-T binding to amyloid fibrils.

Journal: Biochimica et biophysica acta 20100701

Title: Analysis of monomeric Abeta (1-40) peptide by capillary electrophoresis.

Journal: The Analyst 20100701

Title: Bifurcated hydrogen bonds stabilize fibrils of poly(L-glutamic) acid.

Journal: The journal of physical chemistry. B 20100624

Title: Laser-induced propagation and destruction of amyloid beta fibrils.

Journal: The Journal of biological chemistry 20100618

Title: Complement protein C1q forms a complex with cytotoxic prion protein oligomers.

Journal: The Journal of biological chemistry 20100618

Title: Characterization of Lewy body pathology in 12- and 16-year-old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society 20100615

Title: The role of the lipid bilayer in tau aggregation.

Journal: Biophysical journal 20100602

Title: Oligomers of beta-amyloid are sequestered into and seed new plaques in the brains of an AD mouse model.

Journal: Experimental neurology 20100601

Title: Density functional theory analysis and spectral studies on amyloid peptide Abeta(28-35) and its mutants A30G and A30I.

Journal: Journal of structural biology 20100601

Title: Catechol derivatives inhibit the fibril formation of amyloid-beta peptides.

Journal: Journal of bioscience and bioengineering 20100601

Title: Dose- and time-dependent alpha-synuclein aggregation induced by ferric iron in SK-N-SH cells.

Journal: Neuroscience bulletin 20100601

Title: Multidimensional structure-activity relationship of a protein in its aggregated states.

Journal: Angewandte Chemie (International ed. in English) 20100525

Title: Strategies to increase the reproducibility of protein fibrillization in plate reader assays.

Journal: Analytical biochemistry 20100515

Title: Burden of neurodegenerative diseases in a cohort of medical examiner subjects.

Journal: Journal of forensic sciences 20100501

Title: Whole-body biodistribution and brain PET imaging with [18F]AV-45, a novel amyloid imaging agent--a pilot study.

Journal: Nuclear medicine and biology 20100501

Title: PB1-F2 influenza A virus protein adopts a beta-sheet conformation and forms amyloid fibers in membrane environments.

Journal: The Journal of biological chemistry 20100423

Title: Intrinsic determinants of neurotoxic aggregate formation by the amyloid beta peptide.

Journal: Biophysical journal 20100421

Title: Development of a proteolytically stable retro-inverso peptide inhibitor of beta-amyloid oligomerization as a potential novel treatment for Alzheimer's disease.

Journal: Biochemistry 20100420

Title: Molecular polymorphism of Abeta in Alzheimer's disease.

Journal: Neurobiology of aging 20100401

Title: Critical role of interfaces and agitation on the nucleation of Abeta amyloid fibrils at low concentrations of Abeta monomers.

Journal: Biochimica et biophysica acta 20100401

Title: A novel, high-efficiency cellular model of fibrillar alpha-synuclein inclusions and the examination of mutations that inhibit amyloid formation.

Journal: Journal of neurochemistry 20100401

Title: Design, synthesis and biological evaluation of indane-2-arylhydrazinylmethylene-1,3-diones and indol-2-aryldiazenylmethylene-3-ones as beta-amyloid aggregation inhibitors.

Journal: European journal of medicinal chemistry 20100401

Title: Curcumin labeling of neuronal fibrillar tau inclusions in human brain samples.

Journal: Journal of neuropathology and experimental neurology 20100401

Title: Supramolecular capsules: under control.

Journal: Nature chemistry 20100401

Title: The interaction of alphaB-crystallin with mature alpha-synuclein amyloid fibrils inhibits their elongation.

Journal: Biophysical journal 20100303

Title: Yeast cell adhesion molecules have functional amyloid-forming sequences.

Journal: Eukaryotic cell 20100301

Title: DnaK/DnaJ/GrpE of Hsp70 system have differing effects on alpha-synuclein fibrillation involved in Parkinson's disease.

Journal: International journal of biological macromolecules 20100301

Title: Ultrafast bond twisting dynamics in amyloid fibril sensor.

Journal: The journal of physical chemistry. B 20100225

Title: Crystal structure of thioflavin-T and its binding to amyloid fibrils: insights at the molecular level.

Journal: Chemical communications (Cambridge, England) 20100221

Title: Probing the amyloid-beta(1-40) fibril environment with substituted tryptophan residues.

Journal: Archives of biochemistry and biophysics 20100215

Title: Lability landscape and protease resistance of human insulin amyloid: a new insight into its molecular properties.

Journal: Journal of molecular biology 20100212

Title: Cooperative metal ion binding to a cucurbit[7]uril-thioflavin T complex: demonstration of a stimulus-responsive fluorescent supramolecular capsule.

Journal: Journal of the American Chemical Society 20100203

Title: Modulation of aggregate size- and shape-distributions of the amyloid-beta peptide by a designed beta-sheet breaker.

Journal: European biophysics journal : EBJ 20100201

Title: Role of zinc along with ascorbic acid and folic acid during long-term in vitro albumin glycation.

Journal: The British journal of nutrition 20100201

Title: Thioflavin T fluorescence in human serum: correlations with vascular health and cardiovascular risk factors.

Journal: Clinical biochemistry 20100201

Title: Novel anilinophthalimide derivatives as potential probes for beta-amyloid plaque in the brain.

Journal: Bioorganic & medicinal chemistry 20100201

Title: Interaction between oligomers of stefin B and amyloid-beta in vitro and in cells.

Journal: The Journal of biological chemistry 20100129

Title: Oligomerization and insulin interactions of proinsulin C-peptide: Threefold relationships to properties of insulin.

Journal: Biochemical and biophysical research communications 20100115

Title: Immunohistochemical analysis of human brain suggests pathological synergism of Alzheimer's disease and diabetes mellitus.

Journal: Neurobiology of disease 20100101

Title: Inhibition of beta 1-40 amyloid fibrillation with N-acetyl-L-cysteine capped quantum dots.

Journal: Biomaterials 20100101

Title: Searching for conditions to form stable protein oligomers with amyloid-like characteristics: The unexplored basic pH.

Journal: Biochimica et biophysica acta 20100101

Title: Amyloid formation: age-related mechanism in Creutzfeldt-Jakob disease?

Journal: Rejuvenation research 20100101

Title: The therapeutic effects of the herbal medicine, Juzen-taiho-to, on amyloid-beta burden in a mouse model of Alzheimer's disease.

Journal: Journal of Alzheimer's disease : JAD 20100101

Title: The interaction of humic substances with the human prion protein fragment 90-231 affects its protease K resistance and cell internalization.

Journal: Journal of biological regulators and homeostatic agents 20100101

Title: Superoxide dismutase 1 and tgSOD1 mouse spinal cord seed fibrils, suggesting a propagative cell death mechanism in amyotrophic lateral sclerosis.

Journal: PloS one 20100101

Title: Three repeat isoforms of tau inhibit assembly of four repeat tau filaments.

Journal: PloS one 20100101

Title: Immunohistological detection of Chlamydia pneumoniae in the Alzheimer's disease brain.

Journal: BMC neuroscience 20100101

Title: Fluorescence quantum yield of thioflavin T in rigid isotropic solution and incorporated into the amyloid fibrils.

Journal: PloS one 20100101

Title: Β-amyloid 1-42 oligomers impair function of human embryonic stem cell-derived forebrain cholinergic neurons.

Journal: PloS one 20100101

Title: [Thioflavin T interaction with amyloid fibrils as an instrument for their studying].

Journal: Tsitologiia 20100101

Title: Binding modes of thioflavin-T to the single-layer beta-sheet of the peptide self-assembly mimics.

Journal: Journal of molecular biology 20091211

Title: Fibril fragmentation enhances amyloid cytotoxicity.

Journal: The Journal of biological chemistry 20091204

Title: Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20091201

Title: Impaired processing of human pro-islet amyloid polypeptide is not a causative factor for fibril formation or membrane damage in vitro.

Journal: Biochemistry 20091124

Title: Tyrosine autofluorescence as a measure of bovine insulin fibrillation.

Journal: Biophysical journal 20091104

Title: Abeta peptide conformation determines uptake and interleukin-1alpha expression by primary microglial cells.

Journal: Neurobiology of aging 20091101

Title: Thioflavin S (NSC71948) interferes with Bcl-2-associated athanogene (BAG-1)-mediated protein-protein interactions.

Journal: The Journal of pharmacology and experimental therapeutics 20091101

Title: Resveratrol inhibits beta-amyloid oligomeric cytotoxicity but does not prevent oligomer formation.

Journal: Neurotoxicology 20091101

Title: Revealing of Saccharomyces cerevisiae yeast cell wall proteins capable of binding thioflavin T, a fluorescent dye specifically interacting with amyloid fibrils.

Journal: Biochemistry. Biokhimiia 20091101

Title: Effects of non-steroidal anti-inflammatory drugs on Abeta deposition in Abeta(1-42) transgenic C. elegans.

Journal: Brain research 20091027

Title: Kinetic analysis of amyloid formation in the presence of heparan sulfate: faster unfolding and change of pathway.

Journal: The Journal of biological chemistry 20091023

Title: Formation mechanism of insulin fibrils and structural aspects of the insulin fibrillation process.

Journal: Current protein & peptide science 20091001

Title: Effect of curcumin on amyloidogenic property of molten globule-like intermediate state of 2,5-diketo-D-gluconate reductase A.

Journal: Biological chemistry 20091001

Title: Mechanism of docosahexaenoic acid-induced inhibition of in vitro Abeta1-42 fibrillation and Abeta1-42-induced toxicity in SH-S5Y5 cells.

Journal: Journal of neurochemistry 20091001

Title: Morphology of self-assembled structures formed by short peptides from the amyloidogenic protein tau depends on the solvent in which the peptides are dissolved.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20091001

Title: The thioflavin T fluorescence assay for amyloid fibril detection can be biased by the presence of exogenous compounds.

Journal: The FEBS journal 20091001

Title: Interactions of thioflavin T with serum albumins: spectroscopic analyses.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090915

Title: The functional curli amyloid is not based on in-register parallel beta-sheet structure.

Journal: The Journal of biological chemistry 20090911

Title: Near-field scanning optical microscopy measurements of fluorescent molecular probes binding to insulin amyloid fibrils.

Journal: The journal of physical chemistry. B 20090903

Title: On the stability of the soluble amyloid aggregates.

Journal: Biophysical journal 20090902

Title: Effects of voluntary and forced exercise on plaque deposition, hippocampal volume, and behavior in the Tg2576 mouse model of Alzheimer's disease.

Journal: Neurobiology of disease 20090901

Title: Zn(II)- and Cu(II)-induced non-fibrillar aggregates of amyloid-beta (1-42) peptide are transformed to amyloid fibrils, both spontaneously and under the influence of metal chelators.

Journal: Journal of neurochemistry 20090901

Title: A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta.

Journal: Bioorganic & medicinal chemistry letters 20090901

Title: Structural characterization of clusterin-chaperone client protein complexes.

Journal: The Journal of biological chemistry 20090814

Title: A New Transgenic Mouse Model of Gerstmann-Straussler-Scheinker Syndrome Caused by the A117V Mutation of PRNP.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090812

Title: Self-assembled hydrogels from poly[N-(2-hydroxypropyl)methacrylamide] grafted with beta-sheet peptides.

Journal: Biomacromolecules 20090810

Title: Self-organization pathways and spatial heterogeneity in insulin amyloid fibril formation.

Journal: The journal of physical chemistry. B 20090806

Title: Comparative study of inhibition at multiple stages of amyloid-beta self-assembly provides mechanistic insight.

Journal: Molecular pharmacology 20090801

Title: D-Ribosylated Tau forms globular aggregates with high cytotoxicity.

Journal: Cellular and molecular life sciences : CMLS 20090801

Title: Inhibition of Abeta42 aggregation using peptides selected from combinatorial libraries.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20090801

Title: Evidence for novel beta-sheet structures in Iowa mutant beta-amyloid fibrils.

Journal: Biochemistry 20090707

Title: Ultrafast torsional dynamics of protein binding dye thioflavin-T in nanoconfined water pool.

Journal: The journal of physical chemistry. B 20090625

Title: Parcellation of human temporal polar cortex: a combined analysis of multiple cytoarchitectonic, chemoarchitectonic, and pathological markers.

Journal: The Journal of comparative neurology 20090620

Title: Amyloid fibril-like structure underlies the aggregate structure across the pH range for beta-lactoglobulin.

Journal: Biophysical journal 20090617

Title: The polyphenol piceid destabilizes preformed amyloid fibrils and oligomers in vitro: hypothesis on possible molecular mechanisms.

Journal: Neurochemical research 20090601

Title: Anti-aggregation and fibril-destabilizing effects of sex hormones on alpha-synuclein fibrils in vitro.

Journal: Experimental neurology 20090601

Title: Detection of interactions of the beta-amyloid peptide with small molecules employing transferred NOEs.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20090601

Title: Neuronal response of peroxisomal and peroxisome-related proteins to chronic and acute Abeta injury.

Journal: Current Alzheimer research 20090601

Title: Rapid aggregation and assembly in aqueous solution of A beta (25-35) peptide.

Journal: Journal of biosciences 20090601

Title: Amyloid beta (1-42) folding multiplicity and single-molecule binding behavior studied with STM.

Journal: Journal of molecular biology 20090515

Title: Dissecting the mechanisms of tissue transglutaminase-induced cross-linking of alpha-synuclein: implications for the pathogenesis of Parkinson disease.

Journal: The Journal of biological chemistry 20090508

Title: Characterization of type I collagen fibril formation using thioflavin T fluorescent dye.

Journal: Journal of biochemistry 20090501

Title: Synthetic lipid vesicles recruit native-like aggregates and affect the aggregation process of the prion Ure2p: insights on vesicle permeabilization and charge selectivity.

Journal: Biophysical journal 20090422

Title: Bovine insulin filaments induced by reducing disulfide bonds show a different morphology, secondary structure, and cell toxicity from intact insulin amyloid fibrils.

Journal: Biophysical journal 20090422

Title: CE can identify small molecules that selectively target soluble oligomers of amyloid beta protein and display antifibrillogenic activity.

Journal: Electrophoresis 20090401

Title: Effects of docosahexaenoic acid on in vitro amyloid beta peptide 25-35 fibrillation.

Journal: Biochimica et biophysica acta 20090401

Title: Agitation and high ionic strength induce amyloidogenesis of a folded PDZ domain in native conditions.

Journal: Biophysical journal 20090318

Title: Existence of different structural intermediates on the fibrillation pathway of human serum albumin.

Journal: Biophysical journal 20090318

Title: Real-time analysis of amyloid fibril formation of alpha-synuclein using a fibrillation-state-specific fluorescent probe of JC-1.

Journal: The Biochemical journal 20090301

Title: Thioflavin T fluorescence assay for beta-lactoglobulin fibrils hindered by DAPH.

Journal: Journal of structural biology 20090301

Title: Photophysical studies on the noncovalent interaction of thioflavin T with cucurbit[n]uril macrocycles.

Journal: The journal of physical chemistry. B 20090219

Title: Design, selection, and characterization of thioflavin-based intercalation compounds with metal chelating properties for application in Alzheimer's disease.

Journal: Journal of the American Chemical Society 20090204

Title: The mechanism of amyloid-fibril formation by stefin B: temperature and protein concentration dependence of the rates.

Journal: Proteins 20090201

Title: Beta-amyloid deposition and functional impairment in the retina of the APPswe/PS1DeltaE9 transgenic mouse model of Alzheimer's disease.

Journal: Investigative ophthalmology & visual science 20090201

Title: Proteolysis of prion protein by cathepsin S generates a soluble beta-structured intermediate oligomeric form, with potential implications for neurotoxic mechanisms.

Journal: European biophysics journal : EBJ 20090201

Title: Smoking and Parkinson's disease: does nicotine affect alpha-synuclein fibrillation?

Journal: Biochimica et biophysica acta 20090201

Title: Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease.

Journal: Neurochemistry international 20090201

Title: Synthesis and biological evaluation of radioiodinated 2NUBTA as a cerebral ischemia marker.

Journal: Bioorganic & medicinal chemistry letters 20090201

Title: Molecular mechanism of thioflavin-T binding to the surface of beta-rich peptide self-assemblies.

Journal: Journal of molecular biology 20090130

Title: A new amyloid-like beta-aggregate with amyloid characteristics, except fibril morphology.

Journal: Journal of molecular biology 20090130

Title: Ovine colostrum nanopeptide affects amyloid beta aggregation.

Journal: FEBS letters 20090105

Title: Garlic extract exhibits antiamyloidogenic activity on amyloid-beta fibrillogenesis: relevance to Alzheimer's disease.

Journal: Phytotherapy research : PTR 20090101

Title: Cytoskeletal alterations differentiate presenilin-1 and sporadic Alzheimer's disease.

Journal: Acta neuropathologica 20090101

Title: Aggregate formation and toxicity by wild-type and R621C synphilin-1 in the nigrostriatal system of mice using adenoviral vectors.

Journal: Journal of neurochemistry 20090101

Title: Amyloid oligomers in diabetic and nondiabetic human pancreas.

Journal: Translational research : the journal of laboratory and clinical medicine 20090101

Title: Tertiary butanol induced amyloidogenesis of hen egg white lysozyme (HEWL) is facilitated by aggregation-prone alkali-induced molten globule like conformational state.

Journal: Protein and peptide letters 20090101

Title: Development of tau aggregation inhibitors for Alzheimer's disease.

Journal: Angewandte Chemie (International ed. in English) 20090101

Title: The synthesis and characterization of [(124)I]IMPY, a thioflavin-S derivative, in transgenic mouse models of Alzheimer's disease.

Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20090101

Title: Rapid method for measurement of acetylcholinesterase activity.

Journal: Bulletin of experimental biology and medicine 20090101

Title: Fibrils from designed non-amyloid-related synthetic peptides induce AA-amyloidosis during inflammation in an animal model.

Journal: PloS one 20090101

Title: Copper abolishes the beta-sheet secondary structure of preformed amyloid fibrils of amyloid-beta(42).

Journal: Journal of Alzheimer's disease : JAD 20090101

Title: RNA aptamers generated against oligomeric Abeta40 recognize common amyloid aptatopes with low specificity but high sensitivity.

Journal: PloS one 20090101

Title: Mechanically functional amyloid fibrils in the adhesive of a marine invertebrate as revealed by Raman spectroscopy and atomic force microscopy.

Journal: Archives of histology and cytology 20090101

Title: The binding of thioflavin T and its neutral analog BTA-1 to protofibrils of the Alzheimer's disease Abeta(16-22) peptide probed by molecular dynamics simulations.

Journal: Journal of molecular biology 20081219

Title: Thioflavin T as a molecular rotor: fluorescent properties of thioflavin T in solvents with different viscosity.

Journal: The journal of physical chemistry. B 20081211

Title: Analysis of the reaction of carbachol with acetylcholinesterase using thioflavin T as a coupled fluorescence reporter.

Journal: Biochemistry 20081209

Title: Intracranial administration of vaccinia virus complement control protein in Mo/Hu APPswe PS1dE9 transgenic mice at an early age shows enhanced performance at a later age using a cheese board maze test.

Journal: Biogerontology 20081201

Title: Docosahexaenoic acid disrupts in vitro amyloid beta(1-40) fibrillation and concomitantly inhibits amyloid levels in cerebral cortex of Alzheimer's disease model rats.

Journal: Journal of neurochemistry 20081201

Title: Formation of highly toxic soluble amyloid beta oligomers by the molecular chaperone prefoldin.

Journal: The FEBS journal 20081201

Title: Thioflavin T hydroxylation at basic pH and its effect on amyloid fibril detection.

Journal: The journal of physical chemistry. B 20081127

Title: Effects of grape seed-derived polyphenols on amyloid beta-protein self-assembly and cytotoxicity.

Journal: The Journal of biological chemistry 20081121

Title: Sulfated polysaccharides promote the assembly of amyloid beta(1-42) peptide into stable fibrils of reduced cytotoxicity.

Journal: The Journal of biological chemistry 20081121

Title: Thioflavin T displays enhanced fluorescence selectively inside anionic micelles and mammalian cells.

Journal: Journal of fluorescence 20081101

Title: Aggregation and conformational studies on a pentapeptide derivative.

Journal: Biochimica et biophysica acta 20081101

Title: Thiazin red as a neuropathological tool for the rapid diagnosis of Alzheimer's disease in tissue imprints.

Journal: Acta neuropathologica 20081101

Title: Aggregates assembled from overexpression of wild-type alpha-synuclein are not toxic to human neuronal cells.

Journal: Journal of neuropathology and experimental neurology 20081101

Title: The ratio of monomeric to aggregated forms of Abeta40 and Abeta42 is an important determinant of amyloid-beta aggregation, fibrillogenesis, and toxicity.

Journal: The Journal of biological chemistry 20081017

Title: Aminostyrylbenzofuran derivatives as potent inhibitors for Abeta fibril formation.

Journal: Bioorganic & medicinal chemistry letters 20081015

Title: Cyanidin 3-O-glucopyranoside protects and rescues SH-SY5Y cells against amyloid-beta peptide-induced toxicity.

Journal: Neuroreport 20081008

Title: Thermally induced denaturation and aggregation of BLG-A: effect of the Cu(2+) and Zn (2+) metal ions.

Journal: European biophysics journal : EBJ 20081001

Title: Acrolein, the toxic endogenous aldehyde, induces neurofilament-L aggregation.

Journal: BMB reports 20080930

Title: Monitoring the reaction of carbachol with acetylcholinesterase by thioflavin T fluorescence and acetylthiocholine hydrolysis.

Journal: Chemico-biological interactions 20080925

Title: Beta-lactoglobulin assembles into amyloid through sequential aggregated intermediates.

Journal: Journal of molecular biology 20080919

Title: Different inhibitory response of cyanidin and methylene blue for filament formation of tau microtubule-binding domain.

Journal: Biochemical and biophysical research communications 20080912

Title: Acridine derivatives inhibit lysozyme aggregation.

Journal: European biophysics journal : EBJ 20080901

Title: Role of conformational change in the C-terminus of beta2-microglobulin in dialysis-related amyloidosis.

Journal: Annals of clinical biochemistry 20080901

Title: Characterization of amyloidogenesis of hen egg lysozyme in concentrated ethanol solution.

Journal: Biochemical and biophysical research communications 20080815

Title: Role of trehalose in moisture-induced aggregation of bovine serum albumin.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080801

Title: Altered binding of thioflavin t to the peripheral anionic site of acetylcholinesterase after phosphorylation of the active site by chlorpyrifos oxon or dichlorvos.

Journal: Toxicology and applied pharmacology 20080801

Title: Tg-SwDI transgenic mice exhibit novel alterations in AbetaPP processing, Abeta degradation, and resilient amyloid angiopathy.

Journal: The American journal of pathology 20080801

Title: Corticosterone and related receptor expression are associated with increased beta-amyloid plaques in isolated Tg2576 mice.

Journal: Neuroscience 20080731

Title: Lipid-derived aldehydes accelerate light chain amyloid and amorphous aggregation.

Journal: Biochemistry 20080722

Title: Water-soluble tripeptide Abeta (9-11) forms amyloid-like fibrils and exhibits neurotoxicity.

Journal: Organic letters 20080703

Title: Unfolding and aggregation of transthyretin by the truncation of 50 N-terminal amino acids.

Journal: Proteins 20080701

Title: Alpha-synuclein aggregation and cell death triggered by energy deprivation and dopamine overload are counteracted by D2/D3 receptor activation.

Journal: Journal of neurochemistry 20080701

Title: Molecular understanding of copper and iron interaction with alpha-synuclein by fluorescence analysis.

Journal: Journal of molecular neuroscience : MN 20080701

Title: Dimorphic aggregation behavior of a fusion polypeptide incorporating a stable protein domain (EGFP) with an amyloidogenic sequence (retroCspA).

Journal: FEBS letters 20080625

Title: Crystal structure of thioflavin T bound to the peripheral site of Torpedo californica acetylcholinesterase reveals how thioflavin T acts as a sensitive fluorescent reporter of ligand binding to the acylation site.

Journal: Journal of the American Chemical Society 20080625

Title: Posterior parahippocampal gyrus pathology in Alzheimer's disease.

Journal: Neuroscience 20080623

Title: The fluorescent amino acid p-cyanophenylalanine provides an intrinsic probe of amyloid formation.

Journal: Chembiochem : a European journal of chemical biology 20080616

Title: Rifampicin does not prevent amyloid fibril formation by human islet amyloid polypeptide but does inhibit fibril thioflavin-T interactions: implications for mechanistic studies of beta-cell death.

Journal: Biochemistry 20080603

Title: Formation of amyloid fibrils by bovine carbonic anhydrase.

Journal: Biochimica et biophysica acta 20080601

Title: On the binding of Thioflavin-T to HET-s amyloid fibrils assembled at pH 2.

Journal: Journal of structural biology 20080601

Title: The flexible C terminus of the rotavirus non-structural protein NSP4 is an important determinant of its biological properties.

Journal: The Journal of general virology 20080601

Title: Effects of amyloid-beta peptides on hydrogen peroxide-metabolizing enzymes in rat brain in vivo.

Journal: Free radical research 20080601

Title: Chiral bifurcation in aggregating insulin: an induced circular dichroism study.

Journal: Journal of molecular biology 20080523

Title: The formation of a novel supramolecular structure by amyloid of poly-L-glutamic acid.

Journal: Biochemical and biophysical research communications 20080509

Title: The (1-63) region of the p53 transactivation domain aggregates in vitro into cytotoxic amyloid assemblies.

Journal: Biophysical journal 20080501

Title: Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers.

Journal: The Journal of biological chemistry 20080418

Title: A multimeric quinacrine conjugate as a potential inhibitor of Alzheimer's beta-amyloid fibril formation.

Journal: Chembiochem : a European journal of chemical biology 20080414

Title: Dissociation from the oligomeric state is the rate-limiting step in fibril formation by kappa-casein.

Journal: The Journal of biological chemistry 20080404

Title: The degree of structural protection at the edge beta-strands determines the pathway of amyloid formation in globular proteins.

Journal: Journal of the American Chemical Society 20080402

Title: Accelerated release of exosome-associated GM1 ganglioside (GM1) by endocytic pathway abnormality: another putative pathway for GM1-induced amyloid fibril formation.

Journal: Journal of neurochemistry 20080401

Title: Inhibition of cytotoxicity and amyloid fibril formation by a D-amino acid peptide that specifically binds to Alzheimer's disease amyloid peptide.

Journal: Protein engineering, design & selection : PEDS 20080401

Title: Cu(II) organizes beta-2-microglobulin oligomers but is released upon amyloid formation.

Journal: Protein science : a publication of the Protein Society 20080401

Title: Secondary nucleation and accessible surface in insulin amyloid fibril formation.

Journal: The journal of physical chemistry. B 20080327

Title: Ligand-induced flocculation of neurotoxic fibrillar Abeta(1-42) by noncovalent crosslinking.

Journal: Chembiochem : a European journal of chemical biology 20080325

Title: Amyloid fibril formation by bovine milk alpha s2-casein occurs under physiological conditions yet is prevented by its natural counterpart, alpha s1-casein.

Journal: Biochemistry 20080325

Title: Inhibition of LTP in vivo by beta-amyloid peptide in different conformational states.

Journal: Brain research 20080304

Title: Mixed macromolecular crowding inhibits amyloid formation of hen egg white lysozyme.

Journal: Biochimica et biophysica acta 20080301

Title: Amyloid-like fibrils in elastin-related polypeptides: structural characterization and elastic properties.

Journal: Biomacromolecules 20080301

Title: Specific fluorescent detection of fibrillar alpha-synuclein using mono- and trimethine cyanine dyes.

Journal: Bioorganic & medicinal chemistry 20080201

Title: Amyloid toxicity is independent of polypeptide sequence, length and chirality.

Journal: Journal of molecular biology 20080118

Title: Phospholipid interaction induces molecular-level polymorphism in apolipoprotein C-II amyloid fibrils via alternative assembly pathways.

Journal: Journal of molecular biology 20080104

Title: Thioflavin derivatives as markers for amyloid-beta fibrils: insights into structural features important for high-affinity binding.

Journal: ChemMedChem 20080101

Title: Congo red and thioflavin-T analogs detect Abeta oligomers.

Journal: Journal of neurochemistry 20080101

Title: Salvianolic acid B inhibits Abeta fibril formation and disaggregates preformed fibrils and protects against Abeta-induced cytotoxicty.

Journal: Neurochemistry international 20080101

Title: [Estimating of changes in the amyloid and prion content of yeast cells].

Journal: Tsitologiia 20080101

Title: Contrasting in vivo effects of two peptide-based amyloid-beta protein aggregation inhibitors in a transgenic mouse model of amyloid deposition.

Journal: Cell transplantation 20080101

Title: Transthyretin protects against A-beta peptide toxicity by proteolytic cleavage of the peptide: a mechanism sensitive to the Kunitz protease inhibitor.

Journal: PloS one 20080101

Title: Whatever happened to Pittsburgh Compound-A?

Journal: Alzheimer disease and associated disorders 20080101

Title: Persisting atypical and cystic forms of Borrelia burgdorferi and local inflammation in Lyme neuroborreliosis.

Journal: Journal of neuroinflammation 20080101

Title: Nano-scale imaging and dynamics of amylin-membrane interactions and its implication in type II diabetes mellitus.

Journal: Methods in cell biology 20080101

Title: Anti-amyloidogenic activity of S-allyl-L-cysteine and its activity to destabilize Alzheimer's beta-amyloid fibrils in vitro.

Journal: Neuroscience letters 20071218

Title: Influence of phosphorus dendrimers on the aggregation of the prion peptide PrP 185-208.

Journal: Biochemical and biophysical research communications 20071207

Title: Differentiating Alzheimer disease-associated aggregates with small molecules.

Journal: Neurobiology of disease 20071201

Title: Promotion of insulin aggregation by protein disulfide isomerase.

Journal: Biochimica et biophysica acta 20071201

Title: Abeta 1-42 induces mild endoplasmic reticulum stress in an aggregation state-dependent manner.

Journal: Antioxidants & redox signaling 20071201

Title: Amyloid adhesins are abundant in natural biofilms.

Journal: Environmental microbiology 20071201

Title: Monitoring the prevention of amyloid fibril formation by alpha-crystallin. Temperature dependence and the nature of the aggregating species.

Journal: The FEBS journal 20071201

Title: Evidence of fibril-like β-sheet structures in a neurotoxic amyloid intermediate of Alzheimer's β-amyloid.

Journal: Nature structural & molecular biology 20071201

Title: Sequence Determinants for Amyloid Fibrillogenesis of Human alpha-Synuclein.

Journal: Journal of molecular biology 20071123

Title: Design of mechanism-based inhibitors of transthyretin amyloidosis: studies with biphenyl ethers and new structural templates.

Journal: Journal of medicinal chemistry 20071115

Title: Evaluation of different culture conditions for high-level soluble expression of human cyclin A2 with pET vector in BL21 (DE3) and spectroscopic characterization of its inclusion body structure.

Journal: Protein expression and purification 20071101

Title: The role of the VQIVYK peptide in tau protein phosphorylation.

Journal: Journal of neurochemistry 20071101

Title: Novel chalcones as probes for in vivo imaging of beta-amyloid plaques in Alzheimer's brains.

Journal: Bioorganic & medicinal chemistry 20071101

Title: Apoptotic death induces Abeta production and fibril formation to a much larger extent than necrotic-like death in CGNs.

Journal: Journal of Alzheimer's disease : JAD 20071101

Title: Conversion of non-fibrillar beta-sheet oligomers into amyloid fibrils in Alzheimer's disease amyloid peptide aggregation.

Journal: Biochemical and biophysical research communications 20071005

Title: Polyfluorinated bis-styrylbenzene beta-amyloid plaque binding ligands.

Journal: Journal of medicinal chemistry 20071004

Title: Soluble oligomers from a non-disease related protein mimic Abeta-induced tau hyperphosphorylation and neurodegeneration.

Journal: Journal of neurochemistry 20071001

Title: Optimization of a polyglutamine aggregation inhibitor peptide (QBP1) using a thioflavin T fluorescence assay.

Journal: Assay and drug development technologies 20071001

Title: TgCRND8 amyloid precursor protein transgenic mice exhibit an altered gamma-secretase processing and an aggressive, additive amyloid pathology subject to immunotherapeutic modulation.

Journal: Biochemistry 20070911

Title: The active site cysteine of the proapoptotic protein glyceraldehyde-3-phosphate dehydrogenase is essential in oxidative stress-induced aggregation and cell death.

Journal: The Journal of biological chemistry 20070907

Title: Phenylthiazolyl-hydrazide and its derivatives are potent inhibitors of tau aggregation and toxicity in vitro and in cells.

Journal: Biochemistry 20070904

Title: Binding mode of Thioflavin T in insulin amyloid fibrils.

Journal: Journal of structural biology 20070901

Title: Aggregation and fibrillation of bovine serum albumin.

Journal: Biochimica et biophysica acta 20070901

Title: Mapping the structural transition in an amyloidogenic apolipoprotein A-I.

Journal: Biochemistry 20070828

Title: Surface structure of amyloid-beta fibrils contributes to cytotoxicity.

Journal: Biochemistry 20070828

Title: Thioflavin T fluorescence anisotropy: an alternative technique for the study of amyloid aggregation.

Journal: Biochemical and biophysical research communications 20070817

Title: Conformational properties of aggregated polypeptides determine ClpB-dependence in the disaggregation process.

Journal: Journal of molecular biology 20070817

Title: Kinetic refolding barrier of guanidinium chloride denatured goose delta-crystallin leads to regular aggregate formation.

Journal: Biophysical journal 20070815

Title: Novel method for quantitative determination of amyloid fibrils of alpha-synuclein and amyloid beta/A4 protein by using resveratrol.

Journal: Analytical biochemistry 20070815

Title: Formation of toxic fibrils of Alzheimer's amyloid beta-protein-(1-40) by monosialoganglioside GM1, a neuronal membrane component.

Journal: Journal of molecular biology 20070810

Title: Role of a novel excipient poly(ethylene glycol)-b-poly(L-histidine) in retention of physical stability of insulin in aqueous solutions.

Journal: Pharmaceutical research 20070801

Title: Cyanine dye-protein interactions: looking for fluorescent probes for amyloid structures.

Journal: Journal of biochemical and biophysical methods 20070801

Title: Cytotoxicity of insulin within its self-assembly and amyloidogenic pathways.

Journal: Journal of molecular biology 20070706

Title: Analytical method for beta-amyloid fibrils using CE-laser induced fluorescence and its application to screening for inhibitors of beta-amyloid protein aggregation.

Journal: Analytical chemistry 20070701

Title: Hyper-homocysteinemia alters amyloid peptide-clusterin interactions and neuroglial network morphology and function in the caudate after intrastriatal injection of amyloid peptides.

Journal: Current Alzheimer research 20070701

Title: High throughput screening for small molecule inhibitors of heparin-induced tau fibril formation.

Journal: Biochemical and biophysical research communications 20070622

Title: Glucagon amyloid-like fibril morphology is selected via morphology-dependent growth inhibition.

Journal: Biochemistry 20070619

Title: Preferential association of serum amyloid P component with fibrillar deposits in familial British and Danish dementias: similarities with Alzheimer's disease.

Journal: Journal of the neurological sciences 20070615

Title: Computational study of thioflavin T torsional relaxation in the excited state.

Journal: The journal of physical chemistry. A 20070607

Title: Study on the binding of Thioflavin T to beta-sheet-rich and non-beta-sheet cavities.

Journal: Journal of structural biology 20070601

Title: Anti-fibrillogenic and fibril-destabilizing activity of nicotine in vitro: implications for the prevention and therapeutics of Lewy body diseases.

Journal: Experimental neurology 20070601

Title: Consequential alterations in haemoglobin structure upon glycation with fructose: prevention by acetylsalicylic acid.

Journal: Journal of biochemistry 20070601

Title: Mulberry leaf extract prevents amyloid beta-peptide fibril formation and neurotoxicity.

Journal: Neuroreport 20070528

Title: Aggregation of lysozyme and of poly(ethylene glycol)-modified lysozyme after adsorption to silica.

Journal: Colloids and surfaces. B, Biointerfaces 20070515

Title: Effects of oxidation on the structure and stability of human low-density lipoprotein.

Journal: Biochemistry 20070515

Title: Cloning and expression of human islet amyloid polypeptide in cultured cells.

Journal: Biochemical and biophysical research communications 20070511

Title: Hsp40 interacts directly with the native state of the yeast prion protein Ure2 and inhibits formation of amyloid-like fibrils.

Journal: The Journal of biological chemistry 20070420

Title: Thioflavin T and birefringence assays to determine the conversion of proteins into fibrils.

Journal: Langmuir : the ACS journal of surfaces and colloids 20070410

Title: Alternative membrane protein conformations in alcohols.

Journal: Biochemistry 20070410

Title: Spectral properties of thioflavin T in solvents with different dielectric properties and in a fibril-incorporated form.

Journal: Journal of proteome research 20070401

Title: Trehalose effects on alpha-crystallin aggregates.

Journal: Biochemical and biophysical research communications 20070323

Title: Linear quantitation of Abeta aggregation using Thioflavin T: reduction in fibril formation by colostrinin.

Journal: Journal of neuroscience methods 20070315

Title: A structural core within apolipoprotein C-II amyloid fibrils identified using hydrogen exchange and proteolysis.

Journal: Journal of molecular biology 20070309

Title: Bis-styrylpyridine and bis-styrylbenzene derivatives as inhibitors for Abeta fibril formation.

Journal: Bioorganic & medicinal chemistry letters 20070301

Title: [Molecular imaging of beta-amyloid plaques in the brain].

Journal: Brain and nerve = Shinkei kenkyu no shinpo 20070301

Title: Spider silk and amyloid fibrils: a structural comparison.

Journal: Macromolecular bioscience 20070212

Title: Kinetics of different processes in human insulin amyloid formation.

Journal: Journal of molecular biology 20070209

Title: Characterisation and physical stability of PEGylated glucagon.

Journal: International journal of pharmaceutics 20070207

Title: Detection and characterization of protein aggregates by fluorescence microscopy.

Journal: International journal of pharmaceutics 20070201

Title: Cerebrospinal fluid of Alzheimer's disease and dementia with Lewy bodies patients enhances alpha-synuclein fibril formation in vitro.

Journal: Experimental neurology 20070201

Title: Kinetic studies of protein L aggregation and disaggregation.

Journal: Biophysical chemistry 20070201

Title: Vitamin A potently destabilizes preformed alpha-synuclein fibrils in vitro: implications for Lewy body diseases.

Journal: Neurobiology of disease 20070201

Title: Formation of amyloid-like fibrils by ovalbumin and related proteins under conditions relevant to food processing.

Journal: Journal of agricultural and food chemistry 20070124

Title: Identification of an amyloidogenic region on keratoepithelin via synthetic peptides.

Journal: FEBS letters 20070123

Title: Amyloid fibrils formation and amorphous aggregation in concanavalin A.

Journal: Biophysical chemistry 20070101

Title: pH-dependent self-assembly of polyalanine peptides.

Journal: Biophysical journal 20070101

Title: Evidence for fibril-like structure in bovine casein micelles.

Journal: Journal of dairy science 20070101

Title: Cystatin C reduces the in vitro formation of soluble Abeta1-42 oligomers and protofibrils.

Journal: Scandinavian journal of clinical and laboratory investigation 20070101

Title: The effects of various membrane physical-chemical properties on the aggregation kinetics of insulin.

Journal: Chemistry and physics of lipids 20070101

Title: Protection by EGb 761 against beta-amyloid-induced neurotoxicity: involvement of NF-kappaB, SIRT1, and MAPKs pathways and inhibition of amyloid fibril formation.

Journal: Free radical biology & medicine 20061215

Title: N- and C-terminal hydrophobic patches are involved in fibrillation of glucagon.

Journal: Biochemistry 20061205

Title: Inhibition of human IAPP fibril formation does not prevent beta-cell death: evidence for distinct actions of oligomers and fibrils of human IAPP.

Journal: American journal of physiology. Endocrinology and metabolism 20061201

Title: Potential inplications of endogenous aldehydes in beta-amyloid misfolding, oligomerization and fibrillogenesis.

Journal: Journal of neurochemistry 20061201

Title: The early stages of amyloid formation: biophysical and structural characterization of human calcitonin pre-fibrillar assemblies.

Journal: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20061201

Title: Molecular heterosis of prion protein beta-oligomers. A potential mechanism of human resistance to disease.

Journal: The Journal of biological chemistry 20061110

Title: Further evidence of local ganglioside-dependent amyloid beta-protein assembly in brain.

Journal: Neuroreport 20061106

Title: Proline and glycine control protein self-organization into elastomeric or amyloid fibrils.

Journal: Structure (London, England : 1993) 20061101

Title: Age- and transgene-related changes in regional cerebral metabolism in PSAPP mice.

Journal: Brain research 20061020

Title: On the seeding and oligomerization of pGlu-amyloid peptides (in vitro).

Journal: Biochemistry 20061017

Title: Oligo(ethylene glycol) derivatives of thioflavin T as inhibitors of protein-amyloid interactions.

Journal: Chembiochem : a European journal of chemical biology 20061001

Title: Amyloid formation in denatured single-mutant lysozymes where residual structures are modulated.

Journal: Protein science : a publication of the Protein Society 20061001

Title: Viral-induced inflammation is accompanied by beta-amyloid plaque reduction in brains of amyloid precursor protein transgenic Tg2576 mice.

Journal: The European journal of neuroscience 20061001

Title: Oleic acid inhibits amyloid formation of the intermediate of alpha-lactalbumin at moderately acidic pH.

Journal: Journal of molecular biology 20060929

Title: Osmolyte trimethylamine N-oxide converts recombinant alpha-helical prion protein to its soluble beta-structured form at high temperature.

Journal: Journal of molecular biology 20060929

Title: Phage display affords peptides that modulate beta-amyloid aggregation.

Journal: Journal of the American Chemical Society 20060913

Title: Inhibitor discovery targeting the intermediate structure of beta-amyloid peptide on the conformational transition pathway: implications in the aggregation mechanism of beta-amyloid peptide.

Journal: Biochemistry 20060912

Title: Cooexpression of FTDP-17 tau and GSK-3beta in transgenic mice induce tau polymerization and neurodegeneration.

Journal: Neurobiology of aging 20060901

Title: Characterisation of the binding of amyloid imaging tracers to rodent Abeta fibrils and rodent-human Abeta co-polymers.

Journal: Biochemical and biophysical research communications 20060901

Title: Amino-terminal domain stability mediates apolipoprotein E aggregation into neurotoxic fibrils.

Journal: Journal of molecular biology 20060901

Title: High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation.

Journal: The FEBS journal 20060901

Title: Uncaria rhynchophylla, a Chinese medicinal herb, has potent antiaggregation effects on Alzheimer's beta-amyloid proteins.

Journal: Journal of neuroscience research 20060801

Title: Memory-related deficits following selective hippocampal expression of Swedish mutation amyloid precursor protein in the rat.

Journal: Experimental neurology 20060801

Title: Characteristics of the binding of thioflavin S to tau paired helical filaments.

Journal: Journal of Alzheimer's disease : JAD 20060801

Title: Cu(II) induces small-size aggregates with amyloid characteristics in two alleles of recombinant ovine prion proteins.

Journal: Biochimica et biophysica acta 20060701

Title: Molecular interactions of dendrimers with amyloid peptides: pH dependence.

Journal: Biomacromolecules 20060701

Title: Lipophilic analogs of thioflavin S as novel amyloid-imaging agents.

Journal: Current Alzheimer research 20060701

Title: The two-stage pathway of ataxin-3 fibrillogenesis involves a polyglutamine-independent step.

Journal: The Journal of biological chemistry 20060623

Title: Collagen plays an active role in the aggregation of beta2-microglobulin under physiopathological conditions of dialysis-related amyloidosis.

Journal: The Journal of biological chemistry 20060616

Title: Kinetics of insulin aggregation: disentanglement of amyloid fibrillation from large-size cluster formation.

Journal: Biophysical journal 20060615

Title: Methods for enhancing the accuracy and reproducibility of Congo red and thioflavin T assays.

Journal: Analytical biochemistry 20060601

Title: Frontotemporal dementia: clinicopathological correlations.

Journal: Annals of neurology 20060601

Title: Proteasomal inhibition hypersensitizes differentiated neuroblastoma cells to oxidative damage.

Journal: Neuroscience letters 20060515

Title: Fluorescence-coupled CD conformational monitoring of filament formation of tau microtubule-binding repeat domain.

Journal: Biochemical and biophysical research communications 20060512

Title: alphaB-crystallin maintains skeletal muscle myosin enzymatic activity and prevents its aggregation under heat-shock stress.

Journal: Journal of molecular biology 20060505

Title: Mechanism of thioflavin T accumulation inside cells overexpressing P-glycoprotein or multidrug resistance-associated protein: role of lipophilicity and positive charge.

Journal: Biochemical and biophysical research communications 20060505

Title: Inhibitors of amyloid toxicity based on beta-sheet packing of Abeta40 and Abeta42.

Journal: Biochemistry 20060502

Title: Intermediate amyloid oligomers of lysozyme: Is their cytotoxicity a particular case or general rule for amyloid?

Journal: Biochemistry. Biokhimiia 20060501

Title: Peripheral region for core cross-beta plays important role in amyloidogenicity.

Journal: Biochemical and biophysical research communications 20060414

Title: Assessing the role of aromatic residues in the amyloid aggregation of human muscle acylphosphatase.

Journal: Protein science : a publication of the Protein Society 20060401

Title: Role of N-terminal familial mutations in prion protein fibrillization and prion amyloid propagation in vitro.

Journal: The Journal of biological chemistry 20060324

Title: Alpha-lipoic acid exhibits anti-amyloidogenicity for beta-amyloid fibrils in vitro.

Journal: Biochemical and biophysical research communications 20060324

Title: Structural basis of the cofactor function of denatured albumin in plasminogen activation by tissue-type plasminogen activator.

Journal: Biochemical and biophysical research communications 20060317

Title: [Dynamics of in vitro amyloid fiber formation of yeast prion protein Sup35NM].

Journal: Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 20060301

Title: Formation of tau inclusions in knock-in mice with familial Alzheimer disease (FAD) mutation of presenilin 1 (PS1).

Journal: The Journal of biological chemistry 20060224

Title: Nonfibrous beta-structured aggregation of an Abeta model peptide (Ad-2alpha) on GM1/DPPC mixed monolayer surfaces.

Journal: Journal of colloid and interface science 20060215

Title: Inhibiting protein-amyloid interactions with small molecules: a surface chemistry approach.

Journal: Bioorganic & medicinal chemistry letters 20060215

Title: Inhibitory effect of minocycline on amyloid beta fibril formation and human microglial activation.

Journal: Glia 20060201

Title: Mutagenesis of the central hydrophobic cluster in Abeta42 Alzheimer's peptide. Side-chain properties correlate with aggregation propensities.

Journal: The FEBS journal 20060201

Title: Inducible expression of Tau repeat domain in cell models of tauopathy: aggregation is toxic to cells but can be reversed by inhibitor drugs.

Journal: The Journal of biological chemistry 20060113

Title: Scanning cysteine mutagenesis analysis of Abeta-(1-40) amyloid fibrils.

Journal: The Journal of biological chemistry 20060113

Title: Deficiency of disulfide bonds facilitating fibrillogenesis of endostatin.

Journal: The Journal of biological chemistry 20060113

Title: Influence of heparin and dendrimers on the aggregation of two amyloid peptides related to Alzheimer's and prion diseases.

Journal: Biochemical and biophysical research communications 20060113

Title: Functional amyloid formation within mammalian tissue.

Journal: PLoS biology 20060101

Title: Structure of amyloid beta fragments in aqueous environments.

Journal: The FEBS journal 20060101

Title: Thioflavins released from nanoparticles target fibrillar amyloid beta in the hippocampus of APP/PS1 transgenic mice.

Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20060101

Title: Shear flow induces amyloid fibril formation.

Journal: Biomacromolecules 20060101

Title: Conformation dependent pro-apoptotic activity of the recombinant human prion protein fragment 90-231.

Journal: International journal of immunopathology and pharmacology 20060101

Title: Direct observation of amyloid growth monitored by total internal reflection fluorescence microscopy.

Journal: Methods in enzymology 20060101

Title: Sedimentation velocity analysis of amyloid oligomers and fibrils.

Journal: Methods in enzymology 20060101

Title: Conformation-dependent anti-amyloid oligomer antibodies.

Journal: Methods in enzymology 20060101

Title: Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease.

Journal: The Journal of biological chemistry 20051230

Title: Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice.

Journal: The Journal of biological chemistry 20051230

Title: Similar patterns of mitochondrial vulnerability and rescue induced by genetic modification of alpha-synuclein, parkin, and DJ-1 in Caenorhabditis elegans.

Journal: The Journal of biological chemistry 20051230

Title: Early events in the fibrillation of monomeric insulin.

Journal: The Journal of biological chemistry 20051230

Title: Amyloid fibril formation by bovine milk kappa-casein and its inhibition by the molecular chaperones alphaS- and beta-casein.

Journal: Biochemistry 20051227

Title: The role of His-18 in amyloid formation by human islet amyloid polypeptide.

Journal: Biochemistry 20051213

Title: Chiral bias of amyloid fibrils revealed by the twisted conformation of Thioflavin T: an induced circular dichroism/DFT study.

Journal: FEBS letters 20051205

Title: Amyloid fibril formation of alpha-synuclein is accelerated by preformed amyloid seeds of other proteins: implications for the mechanism of transmissible conformational diseases.

Journal: The Journal of biological chemistry 20051118

Title: Radioiodinated flavones for in vivo imaging of beta-amyloid plaques in the brain.

Journal: Journal of medicinal chemistry 20051117

Title: Structural studies reveal that the diverse morphology of beta(2)-microglobulin aggregates is a reflection of different molecular architectures.

Journal: Biochimica et biophysica acta 20051110

Title: The mitochondrial complex I inhibitor rotenone triggers a cerebral tauopathy.

Journal: Journal of neurochemistry 20051101

Title: Cerebrospinal fluid of Alzheimer patients promotes beta-amyloid fibril formation in vitro.

Journal: Neurobiology of disease 20051101

Title: Synthesis of 6-[2-(benzoxazol-2-ylmethylamino)ethoxy]-1-alkyl-1H-indole-2-carboxylic acid and inhibitory activity on beta-amyloid aggregation.

Journal: Archives of pharmacal research 20051101

Title: Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer disease and familial British dementia.

Journal: The Journal of biological chemistry 20051028

Title: In vivo magnetic resonance microimaging of individual amyloid plaques in Alzheimer's transgenic mice.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20051026

Title: Characterization of oligomeric intermediates in alpha-synuclein fibrillation: FRET studies of Y125W/Y133F/Y136F alpha-synuclein.

Journal: Journal of molecular biology 20051021

Title: Controlling {beta}-amyloid oligomerization by the use of naphthalene sulfonates: trapping low molecular weight oligomeric species.

Journal: The Journal of biological chemistry 20051014

Title: Sequence determinants of enhanced amyloidogenicity of Alzheimer A{beta}42 peptide relative to A{beta}40.

Journal: The Journal of biological chemistry 20051014

Title: Haploinsufficiency for trkB and trkC receptors induces cell loss and accumulation of alpha-synuclein in the substantia nigra.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051001

Title: Main-chain dominated amyloid structures demonstrated by the effect of high pressure.

Journal: Journal of molecular biology 20050930

Title: Helix-turn-helix peptides that form alpha-helical fibrils: turn sequences drive fibril structure.

Journal: Biochemistry 20050927

Title: Thermodynamics of A beta(1-40) amyloid fibril elongation.

Journal: Biochemistry 20050927

Title: Ultrasonication-induced amyloid fibril formation of beta2-microglobulin.

Journal: The Journal of biological chemistry 20050923

Title: Effects of the sequence and size of non-polar residues on self-assembly of amphiphilic peptides.

Journal: International journal of biological macromolecules 20050915

Title: Amyloid-like fibril formation of co-chaperonin GroES: nucleation and extension prefer different degrees of molecular compactness.

Journal: Journal of molecular biology 20050902

Title: Mechanism of thioflavin T binding to amyloid fibrils.

Journal: Journal of structural biology 20050901

Title: Cyanine dye N744 inhibits tau fibrillization by blocking filament extension: implications for the treatment of tauopathic neurodegenerative diseases.

Journal: Biochemistry 20050802

Title: Dopamine promotes alpha-synuclein aggregation into SDS-resistant soluble oligomers via a distinct folding pathway.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050801

Title: Aluminum-triggered structural modifications and aggregation of beta-amyloids.

Journal: Cellular and molecular life sciences : CMLS 20050801

Title: Influence of the N-terminal domain on the aggregation properties of the prion protein.

Journal: Protein science : a publication of the Protein Society 20050801

Title: Thermostable direct hemolysin of Vibrio parahaemolyticus is a bacterial reversible amyloid toxin.

Journal: Biochemistry 20050726

Title: Abeta42 is essential for parenchymal and vascular amyloid deposition in mice.

Journal: Neuron 20050721

Title: On the chaperonin activity of GroEL at heat-shock temperature.

Journal: The international journal of biochemistry & cell biology 20050701

Title: Water-soluble hybrid nanoclusters with extra bright and photostable emissions: a new tool for biological imaging.

Journal: Biophysical journal 20050701

Title: Transformation of diffuse beta-amyloid precursor protein and beta-amyloid deposits to plaques in the thalamus after transient occlusion of the middle cerebral artery in rats.

Journal: Stroke 20050701

Title: The aggregation kinetics of Alzheimer's beta-amyloid peptide is controlled by stochastic nucleation.

Journal: Protein science : a publication of the Protein Society 20050701

Title: Inducible neuronal expression of transgenic TGF-beta1 in vivo: dissection of short-term and long-term effects.

Journal: The European journal of neuroscience 20050701

Title: Ethanol-perturbed amyloidogenic self-assembly of insulin: looking for origins of amyloid strains.

Journal: Biochemistry 20050628

Title: Oxidation of low-density lipoproteins induces amyloid-like structures that are recognized by macrophages.

Journal: Biochemistry 20050628

Title: Delineation of positron emission tomography imaging agent binding sites on beta-amyloid peptide fibrils.

Journal: The Journal of biological chemistry 20050624

Title: Amidation and structure relaxation abolish the neurotoxicity of the prion peptide PrP106-126 in vivo and in vitro.

Journal: The Journal of biological chemistry 20050617

Title: Protective effect of donepezil against Abeta(1-40) neurotoxicity in rat septal neurons.

Journal: Brain research 20050614

Title: Higher-order molecular packing in amyloid-like fibrils constructed with linear arrangements of hydrophobic and hydrogen-bonding side-chains.

Journal: Journal of molecular biology 20050513

Title: Activity, folding, misfolding, and aggregation in vitro of the naturally occurring human tissue factor mutant R200W.

Journal: Biochemistry 20050510

Title: The SC3 hydrophobin self-assembles into a membrane with distinct mass transfer properties.

Journal: Biophysical journal 20050501

Title: Collagenous Alzheimer amyloid plaque component assembles amyloid fibrils into protease resistant aggregates.

Journal: The FEBS journal 20050501

Title: Heat shock protein 70 inhibits alpha-synuclein fibril formation via preferential binding to prefibrillar species.

Journal: The Journal of biological chemistry 20050415

Title: Efficient radiosynthesis of carbon-11 labelled uncharged Thioflavin T derivatives using [11C]methyl triflate for beta-amyloid imaging in Alzheimer's Disease with PET.

Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20050401

Title: Development of novel amyloid imaging agents based upon thioflavin S.

Journal: Current Alzheimer research 20050401

Title: Unfolding, aggregation, and seeded amyloid formation of lysine-58-cleaved beta 2-microglobulin.

Journal: Biochemistry 20050322

Title: Investigating the effects of mutations on protein aggregation in the cell.

Journal: The Journal of biological chemistry 20050318

Title: CLAC binds to amyloid beta peptides through the positively charged amino acid cluster within the collagenous domain 1 and inhibits formation of amyloid fibrils.

Journal: The Journal of biological chemistry 20050304

Title: Evidence for the presence of three distinct binding sites for the thioflavin T class of Alzheimer's disease PET imaging agents on beta-amyloid peptide fibrils.

Journal: The Journal of biological chemistry 20050304

Title: Multiple ligand binding sites on A beta(1-40) fibrils.

Journal: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20050301

Title: Fibrillogenesis of apomyoglobin facilitated by aggregation sequence of yeast Sup35 in various regions.

Journal: FEBS letters 20050227

Title: Role of amyloid type cross beta-structure in the formation of soluble aggregate and gel in heat-induced ovalbumin.

Journal: Journal of agricultural and food chemistry 20050223

Title: Single-site mutations in a hyperthermophilic variant of the B1 domain of protein G result in self-assembled oligomers.

Journal: Biochemistry 20050222

Title: Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo.

Journal: The Journal of biological chemistry 20050218

Title: Amyloid-beta protofibrils differ from amyloid-beta aggregates induced in dilute hexafluoroisopropanol in stability and morphology.

Journal: The Journal of biological chemistry 20050128

Title: The binding of thioflavin-T to amyloid fibrils: localisation and implications.

Journal: Journal of structural biology 20050101

Title: Purification of recombinant tau protein and preparation of Alzheimer-paired helical filaments in vitro.

Journal: Methods in molecular biology (Clifton, N.J.) 20050101

Title: Histological staining of amyloid-beta in mouse brains.

Journal: Methods in molecular biology (Clifton, N.J.) 20050101

Title: Circular dichroism and aggregation studies of amyloid beta (11-8) fragment and its variants.

Journal: Acta biochimica Polonica 20050101

Title: Protective effect of zinc on amyloid-beta 25-35 and 1-40 mediated toxicity.

Journal: Neurotoxicity research 20050101

Title: Glycogen synthase kinase 3 beta induces caspase-cleaved tau aggregation in situ.

Journal: The Journal of biological chemistry 20041224

Title: An intersheet packing interaction in A beta fibrils mapped by disulfide cross-linking.

Journal: Biochemistry 20041214

Title: Unraveling the amyloid associated with human medullary thyroid carcinoma.

Journal: Endocrinology 20041201

Title: Inhibition of amyloid fibrillogenesis and toxicity by a peptide chaperone.

Journal: Molecular and cellular biochemistry 20041201

Title: alpha-synuclein is required for the fibrillar nature of ubiquitinated inclusions induced by proteasomal inhibition in primary neurons.

Journal: The Journal of biological chemistry 20041105

Title: Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases.

Journal: The Journal of biological chemistry 20041105

Title: A designed protein interface that blocks fibril formation.

Journal: Journal of the American Chemical Society 20041103

Title: Anionic contribution for fibrous maturation of protofibrillar assemblies of the human tau repeat domain in a fluoroalcohol solution.

Journal: Biochemistry 20041026

Title: An in vitro screening assay based on synthetic prion protein peptides for identification of fibril-interfering compounds.

Journal: Analytical biochemistry 20041015

Title: Vitamin A exhibits potent antiamyloidogenic and fibril-destabilizing effects in vitro.

Journal: Experimental neurology 20041001

Title: Mechanism of prion propagation: amyloid growth occurs by monomer addition.

Journal: PLoS biology 20041001

Title: Apolipoprotein is required for the formation of filamentous amyloid, but not for amorphous Abeta deposition, in an AbetaPP/PS double transgenic mouse model of Alzheimer's disease.

Journal: Journal of Alzheimer's disease : JAD 20041001

Title: Amyloid fibril formation by a partially structured intermediate state of alpha-chymotrypsin.

Journal: Journal of molecular biology 20040903

Title: Nordihydroguaiaretic acid does not disaggregate beta-amyloid(1-40) protofibrils but does inhibit growth arising from direct protofibril association.

Journal: Molecular pharmacology 20040901

Title: Morphological characterization of Thioflavin-S-positive amyloid plaques in transgenic Alzheimer mice and effect of passive Abeta immunotherapy on their clearance.

Journal: The American journal of pathology 20040901

Title: Targeting the neurotoxic species in Alzheimer's disease: inhibitors of Abeta oligomerization.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040901

Title: Differential expression of cholesterol hydroxylases in Alzheimer's disease.

Journal: The Journal of biological chemistry 20040813

Title: Inflammation occurs early during the Abeta deposition process in TgCRND8 mice.

Journal: Neurobiology of aging 20040801

Title: Walnut extract inhibits the fibrillization of amyloid beta-protein, and also defibrillizes its preformed fibrils.

Journal: Current Alzheimer research 20040801

Title: Mostly separate distributions of CLAC- versus Abeta40- or thioflavin S-reactivities in senile plaques reveal two distinct subpopulations of beta-amyloid deposits.

Journal: The American journal of pathology 20040701

Title: The human serpin proteinase inhibitor-9 self-associates at physiological temperatures.

Journal: Protein science : a publication of the Protein Society 20040701

Title: The flavonoid baicalein inhibits fibrillation of alpha-synuclein and disaggregates existing fibrils.

Journal: The Journal of biological chemistry 20040625

Title: Transthyretin aggregation under partially denaturing conditions is a downhill polymerization.

Journal: Biochemistry 20040615

Title: Single chain variable fragments against beta-amyloid (Abeta) can inhibit Abeta aggregation and prevent abeta-induced neurotoxicity.

Journal: Biochemistry 20040608

Title: Annular oligomeric amyloid intermediates observed by in situ atomic force microscopy.

Journal: The Journal of biological chemistry 20040604

Title: Cholinergic nucleus basalis tauopathy emerges early in the aging-MCI-AD continuum.

Journal: Annals of neurology 20040601

Title: NMR of alpha-synuclein-polyamine complexes elucidates the mechanism and kinetics of induced aggregation.

Journal: The EMBO journal 20040519

Title: A seed for Alzheimer amyloid in the brain.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040519

Title: Early-onset and robust cerebral microvascular accumulation of amyloid beta-protein in transgenic mice expressing low levels of a vasculotropic Dutch/Iowa mutant form of amyloid beta-protein precursor.

Journal: The Journal of biological chemistry 20040507

Title: Proteins can convert to beta-sheet in single crystals.

Journal: Protein science : a publication of the Protein Society 20040501

Title: Seeding specificity in amyloid growth induced by heterologous fibrils.

Journal: The Journal of biological chemistry 20040423

Title: Molecular basis of barriers for interspecies transmissibility of mammalian prions.

Journal: Molecular cell 20040409

Title: The HPV16 E7 viral oncoprotein self-assembles into defined spherical oligomers.

Journal: Biochemistry 20040330

Title: Fibrillogenesis and cytotoxic activity of the amyloid-forming apomyoglobin mutant W7FW14F.

Journal: The Journal of biological chemistry 20040326

Title: Inhibiting aggregation of alpha-synuclein with human single chain antibody fragments.

Journal: Biochemistry 20040316

Title: Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro.

Journal: Journal of neuroscience research 20040315

Title: Pseudophosphorylation of tau protein alters its ability for self-aggregation.

Journal: Journal of neurochemistry 20040301

Title: Evidence for an intermediate in tau filament formation.

Journal: Biochemistry 20040217

Title: The human amyloid-beta precursor protein770 mutation V717F generates peptides longer than amyloid-beta-(40-42) and flocculent amyloid aggregates.

Journal: The Journal of biological chemistry 20040213

Title: Neuronal localization of C1q in preclinical Alzheimer's disease.

Journal: Neurobiology of disease 20040201

Title: An engineered PrPsc-like molecule from the chimera of mammalian prion protein and yeast Ure2p prion-inducing domain.

Journal: Acta biochimica et biophysica Sinica 20040201

Title: Amyloid nucleation and hierarchical assembly of Ure2p fibrils. Role of asparagine/glutamine repeat and nonrepeat regions of the prion domains.

Journal: The Journal of biological chemistry 20040130

Title: Amyloid fibril formation by lens crystallin proteins and its implications for cataract formation.

Journal: The Journal of biological chemistry 20040130

Title: Effect of different anti-Abeta antibodies on Abeta fibrillogenesis as assessed by atomic force microscopy.

Journal: Journal of molecular biology 20040123

Title: In vivo labeling of amyloid with BF-108.

Journal: Neuroscience research 20040101

Title: Imaging beta-amyloid plaques and neurofibrillary tangles in the aging human brain.

Journal: Current pharmaceutical design 20040101

Title: Cholesterol, copper, and accumulation of thioflavine S-reactive Alzheimer's-like amyloid beta in rabbit brain.

Journal: Journal of molecular neuroscience : MN 20040101

Title: Neuronal fibrillogenesis: amyloid fibrils from primary neuronal cultures impair long-term memory in the crab Chasmagnathus.

Journal: Behavioural brain research 20031217

Title: [Therapeutics for prion diseases].

Journal: Rinsho shinkeigaku = Clinical neurology 20031101

Title: Glycation induces formation of amyloid cross-beta structure in albumin.

Journal: The Journal of biological chemistry 20031024

Title: Partially folded intermediates in insulin fibrillation.

Journal: Biochemistry 20031007

Title: Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: implications for the prevention and therapeutics of Alzheimer's disease.

Journal: Journal of neurochemistry 20031001

Title: The role of protein stability, solubility, and net charge in amyloid fibril formation.

Journal: Protein science : a publication of the Protein Society 20031001

Title: Proteasome inhibition stabilizes tau inclusions in oligodendroglial cells that occur after treatment with okadaic acid.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20031001

Title: Nitration of tau protein is linked to neurodegeneration in tauopathies.

Journal: The American journal of pathology 20030901

Title: An amyloid-like C-terminal domain of thrombospondin-1 displays CD47 agonist activity requiring both VVM motifs.

Journal: Biochemistry 20030826

Title: Hydrogen exchange-mass spectrometry analysis of beta-amyloid peptide structure.

Journal: Biochemistry 20030812

Title: A peptide motif consisting of glycine, alanine, and valine is required for the fibrillization and cytotoxicity of human alpha-synuclein.

Journal: Biochemistry 20030729

Title: A systematic investigation into the effect of protein destabilisation on beta 2-microglobulin amyloid formation.

Journal: Journal of molecular biology 20030725

Title: Amyloid protofilaments from the calcium-binding protein equine lysozyme: formation of ring and linear structures depends on pH and metal ion concentration.

Journal: Journal of molecular biology 20030718

Title: Structural transformations of oligomeric intermediates in the fibrillation of the immunoglobulin light chain LEN.

Journal: Biochemistry 20030708

Title: Specific compositions of amyloid-beta peptides as the determinant of toxic beta-aggregation.

Journal: The Journal of biological chemistry 20030627

Title: Analysis of yeast prion aggregates with amyloid-staining compound in vivo.

Journal: Cell structure and function 20030601

Title: Amyloid-like fibril formation in an all beta-barrel protein. Partially structured intermediate state(s) is a precursor for fibril formation.

Journal: The Journal of biological chemistry 20030516

Title: Unmasking tandem site interaction in human acetylcholinesterase. Substrate activation with a cationic acetanilide substrate.

Journal: Biochemistry 20030513

Title: Direct observation of amyloid fibril growth monitored by thioflavin T fluorescence.

Journal: The Journal of biological chemistry 20030509

Title: Direct determination of the proportion of intra- and extra-cellular neocortical neurofibrillary tangles in Alzheimer's disease.

Journal: Brain research 20030502

Title: Intracranially administered anti-Abeta antibodies reduce beta-amyloid deposition by mechanisms both independent of and associated with microglial activation.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030501

Title: Environmental influences on bovine kappa-casein: reduction and conversion to fibrillar (amyloid) structures.

Journal: Journal of protein chemistry 20030401

Title: X-ray absorption spectroscopy reveals a substantial increase of sulfur oxidation in transthyretin (TTR) upon fibrillization.

Journal: The Journal of biological chemistry 20030328

Title: Reversible amyloid formation by the p53 tetramerization domain and a cancer-associated mutant.

Journal: Journal of molecular biology 20030328

Title: In vivo imaging of reactive oxygen species specifically associated with thioflavine S-positive amyloid plaques by multiphoton microscopy.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030315

Title: Conformational behavior and aggregation of alpha-synuclein in organic solvents: modeling the effects of membranes.

Journal: Biochemistry 20030311

Title: Mutations in the B1 domain of protein G that delay the onset of amyloid fibril formation in vitro.

Journal: Protein science : a publication of the Protein Society 20030301

Title: Electron microscopic analysis of nanoparticles delivering thioflavin-T after intrahippocampal injection in mouse: implications for targeting beta-amyloid in Alzheimer's disease.

Journal: Neuroscience letters 20030227

Title: In vivo multiphoton imaging of a transgenic mouse model of Alzheimer disease reveals marked thioflavine-S-associated alterations in neurite trajectories.

Journal: Journal of neuropathology and experimental neurology 20030201

Title: Conformational restriction via cyclization in beta-amyloid peptide Abeta(1-28) leads to an inhibitor of Abeta(1-28) amyloidogenesis and cytotoxicity.

Journal: Chemistry & biology 20030201

Title: Probing the role of backbone hydrogen bonding in beta-amyloid fibrils with inhibitor peptides containing ester bonds at alternate positions.

Journal: Biochemistry 20030121

Title: Experimental evidence for multiple assembled states of Sc3 from Schizophyllum commune.

Journal: Biomacromolecules 20030101

Title: Characterization of radioiodinated ligand binding to amyloid beta plaques.

Journal: Journal of molecular neuroscience : MN 20030101

Title: Neuroprotection against Abeta and glutamate toxicity by melatonin: are GABA receptors involved?

Journal: Neurotoxicity research 20030101

Title: Oxidation-induced misfolding and aggregation of superoxide dismutase and its implications for amyotrophic lateral sclerosis.

Journal: The Journal of biological chemistry 20021206

Title: Acid Denaturation of alpha1-antitrypsin: characterization of a novel mechanism of serpin polymerization.

Journal: Journal of molecular biology 20021206

Title: Molecular imaging of amyloid beta peptides in mouse brain sections using mass spectrometry.

Journal: Analytical biochemistry 20021201

Title: IMPY: an improved thioflavin-T derivative for in vivo labeling of beta-amyloid plaques.

Journal: Brain research 20021129

Title: Amyloid fibril formation by a synthetic peptide from a region of human acetylcholinesterase that is homologous to the Alzheimer's amyloid-beta peptide.

Journal: Biochemistry 20021119

Title: New class of inhibitors of amyloid-beta fibril formation. Implications for the mechanism of pathogenesis in Alzheimer's disease.

Journal: The Journal of biological chemistry 20021108

Title: Synthesis of (-)-5,8-dihydroxy-3R-methyl-2R-(dipropylamino)-1,2,3,4-tetrahydronaphthalene: an inhibitor of beta-amyloid(1-42) aggregation.

Journal: Bioorganic & medicinal chemistry 20021101

Title: BIGH3 (TGFBI) Arg124 mutations influence the amyloid conversion of related peptides in vitro.

Journal: European journal of biochemistry 20021101

Title: Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20021101

Title: Molecular targeting of Alzheimer's amyloid plaques for contrast-enhanced magnetic resonance imaging.

Journal: Neurobiology of disease 20021101

Title: Circumvention of chaperone requirement for aggregate formation of a short polyglutamine tract by the co-expression of a long polyglutamine tract.

Journal: The Journal of biological chemistry 20021004

Title: Aggregation and self-assembly of hydrophobins from Trichoderma reesei: low-resolution structural models.

Journal: Biophysical journal 20021001

Title: Non-Fc-mediated mechanisms are involved in clearance of amyloid-beta in vivo by immunotherapy.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020915

Title: Dependence of alpha-synuclein aggregate morphology on solution conditions.

Journal: Journal of molecular biology 20020913

Title: DNA-induced partial unfolding of prion protein leads to its polymerisation to amyloid.

Journal: Journal of molecular biology 20020906

Title: Amyloid formation in rat transthyretin: effect of oxidative stress.

Journal: Clinica chimica acta; international journal of clinical chemistry 20020901

Title: Microvascular reperfusion injury: rapid expansion of anatomic no reflow during reperfusion in the rabbit.

Journal: American journal of physiology. Heart and circulatory physiology 20020901

Title: Beta-amyloid plaques in a model for sporadic Alzheimer's disease based on transgenic anti-nerve growth factor antibodies.

Journal: Molecular and cellular neurosciences 20020901

Title: A novel compound, RS-1178, specifically inhibits neuronal cell death mediated by beta-amyloid-induced macrophage activation in vitro.

Journal: Brain research 20020816

Title: Kinetics and energetics of assembly, nucleation, and growth of aggregates and fibrils for an amyloidogenic protein. Insights into transition states from pressure, temperature, and co-solute studies.

Journal: The Journal of biological chemistry 20020726

Title: Amyloid architecture: complementary assembly of heterogeneous combinations of three or four peptides into amyloid fibrils.

Journal: Chembiochem : a European journal of chemical biology 20020702

Title: Concurrence of alpha-synuclein and tau brain pathology in the Contursi kindred.

Journal: Acta neuropathologica 20020701

Title: Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site.

Journal: Neurobiology of disease 20020701

Title: The ceruloplasmin and hydrogen peroxide system induces alpha-synuclein aggregation in vitro.

Journal: Biochimie 20020701

Title: Conformation of beta 2-microglobulin amyloid fibrils analyzed by reduction of the disulfide bond.

Journal: The Journal of biological chemistry 20020614

Title: Amyloid-like features of polyglutamine aggregates and their assembly kinetics.

Journal: Biochemistry 20020611

Title: Substitution of isoleucine-31 by helical-breaking proline abolishes oxidative stress and neurotoxic properties of Alzheimer's amyloid beta-peptide.

Journal: Free radical biology & medicine 20020601

Title: Suppression of apolipoprotein C-II amyloid formation by the extracellular chaperone, clusterin.

Journal: European journal of biochemistry 20020601

Title: Synthesis, aggregation, neurotoxicity, and secondary structure of various A beta 1-42 mutants of familial Alzheimer's disease at positions 21-23.

Journal: Biochemical and biophysical research communications 20020531

Title: A protein sequence that can encode native structure by disfavoring alternate conformations.

Journal: Nature structural biology 20020501

Title: Nordihydroguaiaretic acid potently breaks down pre-formed Alzheimer's beta-amyloid fibrils in vitro.

Journal: Journal of neurochemistry 20020501

Title: Amyloid fibrils from the mammalian protein prothymosin alpha.

Journal: FEBS letters 20020424

Title: Disassembly of amyloid beta-protein fibril by basement membrane components.

Journal: Life sciences 20020405

Title: Prion peptide 106-126 as a model for prion replication and neurotoxicity.

Journal: Frontiers in bioscience : a journal and virtual library 20020401

Title: Comparative analysis of an improved thioflavin-s stain, Gallyas silver stain, and immunohistochemistry for neurofibrillary tangle demonstration on the same sections.

Journal: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20020401

Title: A designed system for assessing how sequence affects alpha to beta conformational transitions in proteins.

Journal: The Journal of biological chemistry 20020322

Title: Macromolecular crowding accelerates amyloid formation by human apolipoprotein C-II.

Journal: The Journal of biological chemistry 20020308

Title: Familial Danish dementia: a novel form of cerebral amyloidosis associated with deposition of both amyloid-Dan and amyloid-beta.

Journal: Journal of neuropathology and experimental neurology 20020301

Title: Type IV collagen prevents amyloid beta-protein fibril formation.

Journal: Life sciences 20020215

Title: A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain.

Journal: Bioorganic & medicinal chemistry letters 20020211

Title: Kinetic partitioning of protein folding and aggregation.

Journal: Nature structural biology 20020201

Title: Human stefin B readily forms amyloid fibrils in vitro.

Journal: Biochimica et biophysica acta 20020131

Title: Investigation of a peptide responsible for amyloid fibril formation of beta 2-microglobulin by achromobacter protease I.

Journal: The Journal of biological chemistry 20020111

Title: Inhibitors of fibril formation and cytotoxicity of beta-amyloid peptide composed of KLVFF recognition element and flexible hydrophilic disrupting element.

Journal: Biochemical and biophysical research communications 20020111

Title: Amyloid-beta deposits in the cerebral cortex of the aged common marmoset (Callithrix jacchus): incidence and chemical composition.

Journal: Acta neuropathologica 20020101

Title: A partially structured species of beta 2-microglobulin is significantly populated under physiological conditions and involved in fibrillogenesis.

Journal: The Journal of biological chemistry 20011214

Title: Solution conditions can promote formation of either amyloid protofilaments or mature fibrils from the HypF N-terminal domain.

Journal: Protein science : a publication of the Protein Society 20011201

Title: Formation of filamentous tau aggregations in transgenic mice expressing V337M human tau.

Journal: Neurobiology of disease 20011201

Title: Early formation of mature amyloid-beta protein deposits in a mutant APP transgenic model depends on levels of Abeta(1-42).

Journal: Journal of neuroscience research 20011115

Title: Plasmin cleaves Abeta42 in vitro and prevents its aggregation into beta-pleated sheet structures.

Journal: Neuroreport 20010917

Title: The molecular chaperone, alpha-crystallin, inhibits amyloid formation by apolipoprotein C-II.

Journal: The Journal of biological chemistry 20010907

Title: Role of the single disulphide bond of beta(2)-microglobulin in amyloidosis in vitro.

Journal: Protein science : a publication of the Protein Society 20010901

Title: Relationship of calbindin D28K-immunoreactive cells and neuropathological changes in the hippocampal formation of Alzheimer's disease.

Journal: Neuropathology : official journal of the Japanese Society of Neuropathology 20010901

Title: Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain.

Journal: Life sciences 20010817

Title: Plaque-induced abnormalities in neurite geometry in transgenic models of Alzheimer disease: implications for neural system disruption.

Journal: Journal of neuropathology and experimental neurology 20010801

Title: Neuroinflammation-induced acceleration of amyloid deposition in the APPV717F transgenic mouse.

Journal: The European journal of neuroscience 20010801

Title: Statistical aspects of quantitative image analysis of beta-amyloid in the APP(V717F) transgenic mouse model of Alzheimer's disease.

Journal: Journal of neuroscience methods 20010730

Title: Inhibition of beta-amyloid(40) fibrillogenesis and disassembly of beta-amyloid(40) fibrils by short beta-amyloid congeners containing N-methyl amino acids at alternate residues.

Journal: Biochemistry 20010727

Title: Multiple ligand interaction of alpha-synuclein produced various forms of protein aggregates in the presence of Abeta25-35, copper, and eosin.

Journal: Brain research 20010720

Title: Conformational characterization of oligomeric intermediates and aggregates in beta-lactoglobulin heat aggregation.

Journal: Protein science : a publication of the Protein Society 20010701

Title: Thioflavin T is a fluorescent probe of the acetylcholinesterase peripheral site that reveals conformational interactions between the peripheral and acylation sites.

Journal: The Journal of biological chemistry 20010629

Title: The relationship between the aggregational state of the amyloid-beta peptides and free radical generation by the peptides.

Journal: Journal of neurochemistry 20010601

Title: Effect of environmental factors on the kinetics of insulin fibril formation: elucidation of the molecular mechanism.

Journal: Biochemistry 20010522

Title: The relationship between Abeta-associated free radical generation and Abeta fibril formation revealed by negative stain electron microscopy and thioflavine-T fluorometric assay.

Journal: Neuroscience letters 20010518

Title: Identification of a novel human islet amyloid polypeptide beta-sheet domain and factors influencing fibrillogenesis.

Journal: Journal of molecular biology 20010504

Title: Complement association with neurons and beta-amyloid deposition in the brains of aged individuals with Down Syndrome.

Journal: Neurobiology of disease 20010401

Title: Promotion of formation of amyloid fibrils by aluminium adenosine triphosphate (AlATP).

Journal: Journal of inorganic biochemistry 20010401

Title: Growth arrest of individual senile plaques in a model of Alzheimer's disease observed by in vivo multiphoton microscopy.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010201

Title: Regional distribution of amyloid-Bri deposition and its association with neurofibrillary degeneration in familial British dementia.

Journal: The American journal of pathology 20010201

Title: Spectroscopic evidence for amyloid-like interfacial self-assembly of hydrophobin Sc3.

Journal: Biochemical and biophysical research communications 20010112

Title: Heterogeneous assembly of complementary peptide pairs into amyloid fibrils with alpha-beta structural transition.

Journal: Chembiochem : a European journal of chemical biology 20010108

Title: Anti-amyloidogenic activity of tetracyclines: studies in vitro.

Journal: FEBS letters 20010105

Title: Fibrillar beta-amyloid evokes oxidative damage in a transgenic mouse model of Alzheimer's disease.

Journal: Neuroscience 20010101

Title: The morphological phenotype of beta-amyloid plaques and associated neuritic changes in Alzheimer's disease.

Journal: Neuroscience 20010101

Title: McLellan ME, et al. In vivo imaging of reactive oxygen species specifically associated with thioflavine S-positive amyloid plaques by multiphoton microscopy. J Neurosci. 2003 Mar 15;23(6):2212-7.

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