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13311-84-7,MFCD00072009
Catalog No.:AA001473

13311-84-7 | 2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide

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5g
98%
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$19.00   $14.00
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10g
98%
in stock  
$24.00   $17.00
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25g
98%
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$54.00   $38.00
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100g
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500g
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA001473
Chemical Name:
2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
CAS Number:
13311-84-7
Molecular Formula:
C11H11F3N2O3
Molecular Weight:
276.2118
MDL Number:
MFCD00072009
SMILES:
O=C(C(C)C)Nc1ccc(c(c1)C(F)(F)F)[N+](=O)[O-]
Properties
Properties
 
BP:
400.3°C at 760 mmHg  
Form:
Solid  
MP:
112 °C  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
352  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
3.3  

Literature

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Title: Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury.

Journal: Archives of toxicology 20180101

Title: Incorporation of metabolic enzymes to improve predictivity of reporter gene assay results for estrogenic and anti-androgenic activity.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20180101

Title: Differentiating true androgen receptor inhibition from cytotoxicity-mediated reduction of reporter-gene transactivation in-vitro.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20171201

Title: Improved androgen specificity of AR-EcoScreen by CRISPR based glucocorticoid receptor knockout.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20171201

Title: Iminoenamine based novel androgen receptor antagonist exhibited anti-prostate cancer activity in androgen independent prostate cancer cells through inhibition of AKT pathway.

Journal: Chemico-biological interactions 20170925

Title: Agonistic and antagonistic effects of phthalates and their urinary metabolites on the steroid hormone receptors ERα, ERβ, and AR.

Journal: Toxicology letters 20170805

Title: Prediction of drug-induced liver injury using keratinocytes.

Journal: Journal of applied toxicology : JAT 20170701

Title: The scaffold protein RACK1 is a target of endocrine disrupting chemicals (EDCs) with important implication in immunity.

Journal: Toxicology and applied pharmacology 20170615

Title: Evaluating the Role of Multidrug Resistance Protein 3 (MDR3) Inhibition in Predicting Drug-Induced Liver Injury Using 125 Pharmaceuticals.

Journal: Chemical research in toxicology 20170515

Title: Anti-androgen 2-hydroxyflutamide modulates cadherin, catenin and androgen receptor phosphorylation in androgen-sensitive LNCaP and androgen-independent PC3 prostate cancer cell lines acting via PI3K/Akt and MAPK/ERK1/2 pathways.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20170401

Title: Humanizing the zebrafish liver shifts drug metabolic profiles and improves pharmacokinetics of CYP3A4 substrates.

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Title: Editor's Highlight: Transgenic Zebrafish Reporter Lines as Alternative In Vivo Organ Toxicity Models.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20170301

Title: Discriminating between adaptive and carcinogenic liver hypertrophy in rat studies using logistic ridge regression analysis of toxicogenomic data: The mode of action and predictive models.

Journal: Toxicology and applied pharmacology 20170301

Title: Incorporation of a metabolizing system in biodetection assays for endocrine active substances.

Journal: ALTEX 20170101

Title: Downscaling procedures reduce chemical use in androgen receptor reporter gene assay.

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Title: Androgen Receptor Involvement in Rat Amelogenesis: An Additional Way for Endocrine-Disrupting Chemicals to Affect Enamel Synthesis.

Journal: Endocrinology 20161101

Title: Manipulation of pre and postnatal androgen environments and anogenital distance in rats.

Journal: Toxicology 20160810

Title: High content analysis assay for prediction of human hepatotoxicity in HepaRG and HepG2 cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20160601

Title: Development and pre-validation of an in vitro transactivation assay for detection of (anti)androgenic potential compounds using 22Rv1/MMTV cells.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20160401

Title: Hydroxyflutamide affects connexin 43 via the activation of PI3K/Akt-dependent pathway but has no effect on the crosstalk between PI3K/Akt and ERK1/2 pathways at the Raf-1 kinase level in primary rat Sertoli cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20160301

Title: The ability of the YAS and AR CALUX assays to detect the additive effects of anti-androgenic fungicide mixtures.

Journal: Toxicology letters 20160122

Title: Role of androgens in dhea-induced rack1 expression and cytokine modulation in monocytes.

Journal: Immunity & ageing : I & A 20160101

Title: Low dose evaluation of the antiandrogen flutamide following a Mode of Action approach.

Journal: Toxicology and applied pharmacology 20151215

Title: The brominated flame retardants TBP-AE and TBP-DBPE antagonize the chicken androgen receptor and act as potential endocrine disrupters in chicken LMH cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20151201

Title: Effect-based assessment of persistent organic pollutant and pesticide dumpsite using mammalian CALUX reporter cell lines.

Journal: Environmental science and pollution research international 20151001

Title: Utilization of human nuclear receptors as an early counter screen for off-target activity: a case study with a compendium of 615 known drugs.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20150601

Title: Temporal changes in biological responses and uncertainty in assessing risks of endocrine-disrupting chemicals: insights from intensive time-course studies with fish.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20150401

Title: Low-dose exposure to bisphenol A and replacement bisphenol S induces precocious hypothalamic neurogenesis in embryonic zebrafish.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20150203

Title: Identification of a group of brominated flame retardants as novel androgen receptor antagonists and potential neuronal and endocrine disrupters.

Journal: Environment international 20150101

Title: 17β-trenbolone, an anabolic-androgenic steroid as well as an environmental hormone, contributes to neurodegeneration.

Journal: Toxicology and applied pharmacology 20150101

Title: Comparative gene and protein expression analyses of a panel of cytokines in acute and chronic drug-induced liver injury in rats.

Journal: Toxicology 20141003

Title: Species-specific considerations in using the fish embryo test as an alternative to identify endocrine disruption.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20141001

Title: Rapid fluorescent detection of (anti)androgens with spiggin-gfp medaka.

Journal: Environmental science & technology 20140916

Title: Investigation of the hepatotoxicity of flutamide: pro-survival/apoptotic and necrotic switch in primary rat hepatocytes characterized by metabolic and transcriptomic profiles in microfluidic liver biochips.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20140801

Title: Identification of gene expression changes in postnatal rat foreskin after in utero anti-androgen exposure.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20140801

Title: Development of a cell-based assay system considering drug metabolism and immune- and inflammatory-related factors for the risk assessment of drug-induced liver injury.

Journal: Toxicology letters 20140703

Title: Testosterone induces apoptosis in vascular smooth muscle cells via extrinsic apoptotic pathway with mitochondria-generated reactive oxygen species involvement.

Journal: American journal of physiology. Heart and circulatory physiology 20140601

Title: Testosterone ameliorates streptozotocin-induced memory impairment in male rats.

Journal: Acta pharmacologica Sinica 20140601

Title: Environmental (anti-)androgenic chemicals affect germinal vesicle breakdown (GVBD) of Xenopus laevis oocytes in vitro.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20140401

Title: A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20140101

Title: Utilization of causal reasoning of hepatic gene expression in rats to identify molecular pathways of idiosyncratic drug-induced liver injury.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20140101

Title: Flutamide-induced cytotoxicity and oxidative stress in an in vitro rat hepatocyte system.

Journal: Oxidative medicine and cellular longevity 20140101

Title: FDA-approved drugs and other compounds tested as inhibitors of human glutathione transferase P1-1.

Journal: Chemico-biological interactions 20130905

Title: Androgen deprivation from pre-puberty to peripuberty interferes in proteins expression in pubertal and adult rat epididymis.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20130701

Title: HepG2 cells simultaneously expressing five P450 enzymes for the screening of hepatotoxicity: identification of bioactivable drugs and the potential mechanism of toxicity involved.

Journal: Archives of toxicology 20130601

Title: Metabolomics-on-a-chip of hepatotoxicity induced by anticancer drug flutamide and Its active metabolite hydroxyflutamide using HepG2/C3a microfluidic biochips.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20130301

Title: Effects of the natural endocrine disruptor equol on the pituitary function in adult male rats.

Journal: Toxicology 20130208

Title: Androgen deprivation by flutamide modulates uPAR, MMP-9 expressions, lipid profile, and oxidative stress: amelioration by daidzein.

Journal: Molecular and cellular biochemistry 20130201

Title: Ligand-independent androgen receptor antagonism caused by the newly developed pesticide pyrifluquinazon (PFQ).

Journal: Reproductive toxicology (Elmsford, N.Y.) 20130101

Title: Nitric oxide inhibits androgen receptor-mediated collagen production in human gingival fibroblasts.

Journal: Journal of periodontal research 20121201

Title: Elevated level of 17β-estradiol is associated with overexpression of FSHR, CYP19A1, and CTNNB1 genes in porcine ovarian follicles after prenatal and neonatal flutamide exposure.

Journal: Theriogenology 20121201

Title: Biopsy Gleason score and the duration of testosterone suppression among men treated with external beam radiation and 6 months of combined androgen blockade.

Journal: BJU international 20121101

Title: Aryl hydrocarbon receptor (AHR)-active pharmaceuticals are selective AHR modulators in MDA-MB-468 and BT474 breast cancer cells.

Journal: The Journal of pharmacology and experimental therapeutics 20121101

Title: The influence of reproductive hormones on the torpor patterns of the marsupial Sminthopsis macroura: bet-hedging in an unpredictable environment.

Journal: General and comparative endocrinology 20121101

Title: Hepatotoxicity with flutamide.

Journal: Fertility and sterility 20121101

Title: In silico discovery of androgen receptor antagonists with activity in castration resistant prostate cancer.

Journal: Molecular endocrinology (Baltimore, Md.) 20121101

Title: Involvement of Th2 cytokines in the mouse model of flutamide-induced acute liver injury.

Journal: Journal of applied toxicology : JAT 20121001

Title: Anti-androgenic effects of S-40542, a novel non-steroidal selective androgen receptor modulator (SARM) for the treatment of benign prostatic hyperplasia.

Journal: The Prostate 20121001

Title: Steroid derivatives as pure antagonists of the androgen receptor.

Journal: The Journal of steroid biochemistry and molecular biology 20121001

Title: Ethinyl estradiol-cyproterone acetate versus low-dose pioglitazone-flutamide-metformin for adolescent girls with androgen excess: divergent effects on CD163, TWEAK receptor, ANGPTL4, and LEPTIN expression in subcutaneous adipose tissue.

Journal: The Journal of clinical endocrinology and metabolism 20121001

Title: Hepatotoxicity with low- and ultralow-dose flutamide: a surveillance study on 203 hyperandrogenic young females.

Journal: Fertility and sterility 20121001

Title: Regression of the mammary branch of the genitofemoral nerve may be necessary for testicular descent in rats.

Journal: The Journal of urology 20121001

Title: Sertoli-secreted FGF-2 induces PFKFB4 isozyme expression in mouse spermatogenic cells by activation of the MEK/ERK/CREB pathway.

Journal: American journal of physiology. Endocrinology and metabolism 20120915

Title: Insulin-like growth factor-1 is associated with regulation of the luteinizing hormone production in men receiving androgen deprivation therapy with gonadotropin-releasing hormone analogues for localized prostate cancer.

Journal: Urologic oncology 20120901

Title: Efficacy of peripheral androgen blockade in prostate cancer patients with biochemical failure after definitive local therapy: results of Cancer and Leukemia Group B (CALGB) 9782.

Journal: Cancer 20120901

Title: Stage-specific effects of androgens and estradiol-17beta on the development of late primary and early secondary ovarian follicles of coho salmon (Oncorhynchus kisutch) in vitro.

Journal: Biology of reproduction 20120901

Title: Cellular actions of testosterone in vascular cells: mechanism independent of aromatization to estradiol.

Journal: Steroids 20120901

Title: PHEA-graft-polybutylmethacrylate copolymer microparticles for delivery of hydrophobic drugs.

Journal: International journal of pharmaceutics 20120820

Title: Flutamide, an androgen receptor antagonist, improves heatstroke outcomes in mice.

Journal: European journal of pharmacology 20120805

Title: Administration of flutamide alters sperm ultrastructure, sperm plasma membrane integrity and its stability, and sperm mitochondrial oxidative capability in the boar: in vivo and in vitro approach.

Journal: Reproduction in domestic animals = Zuchthygiene 20120801

Title: Upfront androgen deprivation therapy with salvage radiation may improve biochemical outcomes in prostate cancer patients with post-prostatectomy rising PSA.

Journal: International journal of radiation oncology, biology, physics 20120801

Title: Addition of radiotherapy to long-term androgen deprivation in locally advanced prostate cancer: an open randomised phase 3 trial.

Journal: European urology 20120801

Title: The anxiolytic effect of testosterone in the rat is mediated via the androgen receptor.

Journal: Pharmacology, biochemistry, and behavior 20120801

Title: Regulation of LKB1 expression by sex hormones in adipocytes.

Journal: International journal of obesity (2005) 20120701

Title: Outcome predictors of radical prostatectomy followed by adjuvant androgen deprivation in patients with clinical high risk prostate cancer and pT3 surgical margin positive disease.

Journal: The Journal of urology 20120701

Title: Antitumor agents 290. Design, synthesis, and biological evaluation of new LNCaP and PC-3 cytotoxic curcumin analogs conjugated with anti-androgens.

Journal: Bioorganic & medicinal chemistry 20120701

Title: Are expression and localization of tight and adherens junction proteins in testes of adult boar affected by foetal and neonatal exposure to flutamide?

Journal: International journal of andrology 20120601

Title: Exposure of neonatal rats to anti-androgens induces penile mal-developments and infertility comparable to those induced by oestrogens.

Journal: International journal of andrology 20120601

Title: Impairment on sperm quality and fertility of adult rats after antiandrogen exposure during prepuberty.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20120601

Title: Flutamide increases aldosterone levels in gonadectomized male but not female Wistar rats.

Journal: American journal of hypertension 20120601

Title: A novel polymorphic allele of human arylacetamide deacetylase leads to decreased enzyme activity.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20120601

Title: Prostate cancer in elderly Croatian men: 5-HT genetic polymorphisms and the influence of androgen deprivation therapy on osteopenia--a pilot study.

Journal: Genetic testing and molecular biomarkers 20120601

Title: Contributions of arylacetamide deacetylase and carboxylesterase 2 to flutamide hydrolysis in human liver.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20120601

Title: Developmental programming: prenatal and postnatal contribution of androgens and insulin in the reprogramming of estradiol positive feedback disruptions in prenatal testosterone-treated sheep.

Journal: Endocrinology 20120601

Title: Inulin-based hydrogel for oral delivery of flutamide: preparation, characterization, and in vivo release studies.

Journal: Macromolecular bioscience 20120601

Title: The influence of testosterone suppression and recovery on sexual function in men with prostate cancer: observations from a prospective study in men undergoing intermittent androgen suppression.

Journal: The Journal of urology 20120601

Title: Fluorinated and pegylated polyaspartamide derivatives to increase solubility and efficacy of Flutamide.

Journal: Journal of drug targeting 20120601

Title: Testosterone induces vascular smooth muscle cell migration by NADPH oxidase and c-Src-dependent pathways.

Journal: Hypertension (Dallas, Tex. : 1979) 20120601

Title: Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.

Journal: Journal of medicinal chemistry 20120524

Title: Long-term dynamics of bone mineral density during intermittent androgen deprivation for men with nonmetastatic, hormone-sensitive prostate cancer.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120520

Title: Insulin resistance in women with hirsutism.

Journal: Archives of medical science : AMS 20120509

Title: Activation of PKR/eIF2α signaling cascade is associated with dihydrotestosterone-induced cell cycle arrest and apoptosis in human liver cells.

Journal: Journal of cellular biochemistry 20120501

Title: Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120501

Title: Prenatal and neonatal flutamide administration increases proliferation and reduces apoptosis in large antral follicles of adult pigs.

Journal: Animal reproduction science 20120501

Title: Testosterone up-regulates seladin-1 expression by iAR and PI3-K/Akt signaling pathway in C6 cells.

Journal: Neuroscience letters 20120411

Title: Androgens affect myogenesis in vitro and increase local IGF-1 expression.

Journal: Medicine and science in sports and exercise 20120401

Title: Prenatal and neonatal exposure to flutamide affects function of Leydig cells in adult boar.

Journal: Domestic animal endocrinology 20120401

Title: Species differences in tissue distribution and enzyme activities of arylacetamide deacetylase in human, rat, and mouse.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20120401

Title: Endosulfan and flutamide, alone and in combination, target ovarian growth in juvenile catfish, Clarias batrachus.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20120401

Title: Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins.

Journal: Cell biology and toxicology 20120401

Title: Testosterone modulates platelet aggregation and endothelial cell growth through nitric oxide pathway.

Journal: The Journal of endocrinology 20120401

Title: Endosulfan and flutamide impair testicular development in the juvenile Asian catfish, Clarias batrachus.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20120401

Title: Serum- and glucocorticoid-dependent kinase-1-induced cell migration is dependent on vinculin and regulated by the membrane androgen receptor.

Journal: The FEBS journal 20120401

Title: Immunomodulatory effects of testosterone evaluated in all-trans retinoic acid differentiated HL-60 cells, granulocytes, and monocytes.

Journal: International immunopharmacology 20120401

Title: The vasodilatory effect of testosterone on renal afferent arterioles.

Journal: Gender medicine 20120401

Title: Dehydroepiandrosterone reduces preadipocyte proliferation via androgen receptor.

Journal: American journal of physiology. Endocrinology and metabolism 20120315

Title: Association of prolactin-induced protein with preputial development of hypospadias.

Journal: BJU international 20120301

Title: Mechanistic study on liver tumor promoting effects of flutamide in rats.

Journal: Archives of toxicology 20120301

Title: Evaluation of drugs with specific organ toxicities in organ-specific cell lines.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120301

Title: Testosterone exerts antiapoptotic effects against H2O2 in C2C12 skeletal muscle cells through the apoptotic intrinsic pathway.

Journal: The Journal of endocrinology 20120301

Title: Regional differences in the vasorelaxing effects of testosterone and its 5-reduced metabolites in the canine vasculature.

Journal: Vascular pharmacology 20120301

Title: Ten-year follow-up of neoadjuvant therapy with goserelin acetate and flutamide before radical prostatectomy for clinical T3 and T4 prostate cancer: update on Southwest Oncology Group Study 9109.

Journal: Urology 20120301

Title: Nilutamide.

Journal: Acta crystallographica. Section E, Structure reports online 20120301

Title: Prostate cancer with neuroendocrine differentiation--case report.

Journal: Journal of medicine and life 20120222

Title: Effect of methanol extract of Basella alba L. (Basellaceae) on the fecundity and testosterone level in male rats exposed to flutamide in utero.

Journal: Andrologia 20120201

Title: The anabolic/androgenic steroid nandrolone exacerbates gene expression modifications induced by mutant SOD1 in muscles of mice models of amyotrophic lateral sclerosis.

Journal: Pharmacological research 20120201

Title: Effect of gonadal steroid hormones on formalin-induced temporomandibular joint inflammation.

Journal: European journal of pain (London, England) 20120201

Title: Novel evidence that testosterone promotes cell proliferation and differentiation via G protein-coupled receptors in the rat L6 skeletal muscle myoblast cell line.

Journal: Journal of cellular physiology 20120101

Title: Surgical castration in hormone-refractory metastatic prostate cancer patients can be an alternative for medical castration.

Journal: Advances in urology 20120101

Title: Testosterone-dependent increase in blood pressure is mediated by elevated Cyp4A expression in fructose-fed rats.

Journal: Molecular and cellular biochemistry 20120101

Title: The role of the androgen receptor in anabolic androgenic steroid-induced aggressive behavior in C57BL/6J and Tfm mice.

Journal: Hormones and behavior 20120101

Title: Androgen signaling in decidualizing human endometrial stromal cells enhances resistance to oxidative stress.

Journal: Fertility and sterility 20120101

Title: Non-classic androgen actions in Sertoli cell membrane in whole seminiferous tubules: effects of nandrolone decanoate and catechin.

Journal: Steroids 20120101

Title: Management of high-risk localized prostate cancer.

Journal: Advances in urology 20120101

Title: Juvenile angiofibroma: evolution of management.

Journal: International journal of pediatrics 20120101

Title: Alterations in vasomotor systems and mechanics of resistance-sized mesenteric arteries from SHR and WKY male rats following in vivo testosterone manipulation.

Journal: Biology of sex differences 20120101

Title: Dehydroepiandrosterone (DHEA) inhibition of monocyte binding by vascular endothelium is associated with sialylation of neural cell adhesion molecule.

Journal: Reproductive sciences (Thousand Oaks, Calif.) 20120101

Title: The 5 alpha-reductase isozyme family: a review of basic biology and their role in human diseases.

Journal: Advances in urology 20120101

Title: Clinical Efficacy of TroVax in the Treatment of Progressive Castration-resistant Prostate Cancer.

Journal: Clinical Medicine Insights. Oncology 20120101

Title: Inter-relationship between testicular dysgenesis and Leydig cell function in the masculinization programming window in the rat.

Journal: PloS one 20120101

Title: Topical androgen antagonism promotes cutaneous wound healing without systemic androgen deprivation by blocking β-catenin nuclear translocation and cross-talk with TGF-β signaling in keratinocytes.

Journal: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20120101

Title: Abiraterone acetate: oral androgen biosynthesis inhibitor for treatment of castration-resistant prostate cancer.

Journal: Drug design, development and therapy 20120101

Title: Androgenic suppression combined with radiotherapy for the treatment of prostate adenocarcinoma: a systematic review.

Journal: BMC cancer 20120101

Title: Novel spectrophotometric method for determination of cinacalcet hydrochloride in its tablets via derivatization with 1,2-naphthoquinone-4-sulphonate.

Journal: Chemistry Central journal 20120101

Title: Fetal radiation exposure induces testicular cancer in genetically susceptible mice.

Journal: PloS one 20120101

Title: The role of adjuvant hormonal treatment after surgery for localized high-risk prostate cancer: results of a matched multiinstitutional analysis.

Journal: Advances in urology 20120101

Title: Androgen receptor drives cellular senescence.

Journal: PloS one 20120101

Title: Cardiac arrest due to lymphocytic colitis: a case report.

Journal: Journal of medical case reports 20120101

Title: Sex differences in primary hypertension.

Journal: Biology of sex differences 20120101

Title: Prenatal exposure to antiandrogen flutamide affects androgen receptor (AR) expression in postnatal ovarian development in pig.

Journal: Folia biologica 20120101

Title: Post-translational modifications of nuclear receptors and human disease.

Journal: Nuclear receptor signaling 20120101

Title: Androgen receptor-beta mRNA levels in different tissues in breeding and post-breeding male and female sticklebacks, Gasterosteus aculeatus.

Journal: Reproductive biology and endocrinology : RB&E 20120101

Title: Redefining hormone sensitive disease in advanced prostate cancer.

Journal: Advances in urology 20120101

Title: MicroRNA-34c enhances murine male germ cell apoptosis through targeting ATF1.

Journal: PloS one 20120101

Title: Low lipoprotein(a) concentration is associated with cancer and all-cause deaths: a population-based cohort study (the JMS cohort study).

Journal: PloS one 20120101

Title: Effects of trauma-hemorrhage and IL-6 deficiency on splenic immune function in a murine trauma model.

Journal: Mediators of inflammation 20120101

Title: Does 2-hydroxyflutamide inhibit apoptosis in porcine granulosa cells? - An in vitro study.

Journal: The Journal of reproduction and development 20120101

Title: Castration-resistant prostate cancer: mechanisms, targets, and treatment.

Journal: Prostate cancer 20120101

Title: The Interactions between Insulin and Androgens in Progression to Castrate-Resistant Prostate Cancer.

Journal: Advances in urology 20120101

Title: Role of endogenous testosterone in TNF-induced myocardial injury in males.

Journal: International journal of clinical and experimental medicine 20120101

Title: Double-blinded, vehicle-controlled proof of concept study to investigate the recurrence of inflammatory and noninflammatory acne lesions using tretinoin gel (microsphere) 0.04% in male patients after oral isotretinoin use.

Journal: Dermatology research and practice 20120101

Title: Screening estrogenic activities of chemicals or mixtures in vivo using transgenic (cyp19a1b-GFP) zebrafish embryos.

Journal: PloS one 20120101

Title: The current role of androgen deprivation in patients undergoing dose-escalated external beam radiation therapy for clinically localized prostate cancer.

Journal: Prostate cancer 20120101

Title: McCune-Albright syndrome and the extraskeletal manifestations of fibrous dysplasia.

Journal: Orphanet journal of rare diseases 20120101

Title: Estrogenic regulation of the GnRH neuron.

Journal: Frontiers in endocrinology 20120101

Title: Flutamide treatment induces anxiolytic-like behavior in adult castrated rats.

Journal: Pharmacological reports : PR 20120101

Title: Emerging targeted therapies for castration-resistant prostate cancer.

Journal: Frontiers in endocrinology 20120101

Title: Radiation, inflammation, and immune responses in cancer.

Journal: Frontiers in oncology 20120101

Title: The emerging role of human esterases.

Journal: Drug metabolism and pharmacokinetics 20120101

Title: Risk of hormone escape in a human prostate cancer model depends on therapy modalities and can be reduced by tyrosine kinase inhibitors.

Journal: PloS one 20120101

Title: Treatment of female pattern hair loss.

Journal: Skinmed 20120101

Title: Postnatal exposure to low-dose decabromodiphenyl ether adversely affects mouse testes by increasing thyrosine phosphorylation level of cortactin.

Journal: The Journal of toxicological sciences 20120101

Title: Physiological effects of androgens on human vascular endothelial and smooth muscle cells in culture.

Journal: Steroids 20111220

Title: Bioassay-directed identification of novel antiandrogenic compounds in bile of fish exposed to wastewater effluents.

Journal: Environmental science & technology 20111215

Title: Differential expression of connexin 43 in adult pig testes during normal spermatogenic cycle and after flutamide treatment.

Journal: Reproduction in domestic animals = Zuchthygiene 20111201

Title: Clinical efficacy of primary combined androgen blockade for Japanese men with clinically localized prostate cancer unsuitable for local definitive treatment: a single institution experience.

Journal: International journal of clinical oncology 20111201

Title: Relative importance of prenatal and postnatal androgen action in determining growth of the penis and anogenital distance in the rat before, during and after puberty.

Journal: International journal of andrology 20111201

Title: Androgen receptor coregulators NOCR1, TIF2, and ARA70 may account for the hydroxyflutamide insensitivity of prostate cancer cells.

Journal: Irish journal of medical science 20111201

Title: Castration inhibits biliary proliferation induced by bile duct obstruction: novel role for the autocrine trophic effect of testosterone.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20111201

Title: A novel steroidal antiandrogen targeting wild type and mutant androgen receptors.

Journal: Biochemical pharmacology 20111201

Title: Developmental programming: gestational testosterone treatment alters fetal ovarian gene expression.

Journal: Endocrinology 20111201

Title: Adjuvant therapy with flutamide for presurgical volume reduction in juvenile nasopharyngeal angiofibroma.

Journal: Head & neck 20111201

Title: The effect of flutamide on expression of androgen and estrogen receptors in the gubernaculum and surrounding structures during testicular descent.

Journal: Journal of pediatric surgery 20111201

Title: Gone with the Wnt: the canonical Wnt signaling axis is present and androgen dependent in the rodent gubernaculum.

Journal: Journal of pediatric surgery 20111201

Title: Testosterone depletion or blockade in male rats protects against trauma hemorrhagic shock-induced distant organ injury by limiting gut injury and subsequent production of biologically active mesenteric lymph.

Journal: The Journal of trauma 20111201

Title: [Monotherapy versus combined androgen blockade for advanced/metastatic prostate cancer].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20111201

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: Cooperative antitumor effect of endothelial-monocyte activating polypeptide II and flutamide on human prostate cancer xenografts.

Journal: Experimental oncology 20111201

Title: Fatty acid-binding protein-4 plasma levels are associated to metabolic abnormalities and response to therapy in girls and young women with androgen excess.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20111101

Title: Significance of pretreatment cardiovascular morbidity as a risk factor during treatment with parenteral oestrogen or combined androgen deprivation of 915 patients with metastasized prostate cancer: evaluation of cardiovascular events in a randomized trial.

Journal: Scandinavian journal of urology and nephrology 20111101

Title: Androgen deprivation therapy through bilateral orchiectomy: increased metabolic risks.

Journal: Asian journal of andrology 20111101

Title: Treatment of androgen excess in adolescent girls: ethinylestradiol-cyproteroneacetate versus low-dose pioglitazone-flutamide-metformin.

Journal: The Journal of clinical endocrinology and metabolism 20111101

Title: Functionally similar acoustic signals in the corncrake (Crex crex) transmit information about different states of the sender during aggressive interactions.

Journal: Hormones and behavior 20111101

Title: Differential cytotoxicity of triphala and its phenolic constituent gallic acid on human prostate cancer LNCap and normal cells.

Journal: Anticancer research 20111101

Title: Retrospective, observational study on the effects and tolerability of flutamide in a large population of patients with acne and seborrhea over a 15-year period.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20111001

Title: Estrogen-regulated genes in rat testes and their relationship to recovery of spermatogenesis after irradiation.

Journal: Biology of reproduction 20111001

Title: Dihydrotestosterone inhibits hair growth in mice by inhibiting insulin-like growth factor-I production in dermal papillae.

Journal: Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20111001

Title: Differential effects of exogenous androgen and an androgen receptor antagonist in the peri- and postpubertal murine mammary gland.

Journal: Endocrinology 20111001

Title: Cremaster muscle myogenesis in the tip of the rat gubernaculum supports active gubernacular elongation during inguinoscrotal testicular descent.

Journal: The Journal of urology 20111001

Title: Combination of resveratrol and antiandrogen flutamide has synergistic effect on androgen receptor inhibition in prostate cancer cells.

Journal: Anticancer research 20111001

Title: Disruption of CD38 gene enhances cardiac functions by elevating serum testosterone in the male null mice.

Journal: Life sciences 20110926

Title: Inhibitors of androgen receptor activation function-2 (AF2) site identified through virtual screening.

Journal: Journal of medicinal chemistry 20110922

Title: Immunohistochemical studies on the proliferative marker Ki-67 and estrogen receptor alpha (ERα) in the uterus of neonatal and immature pigs following exposure to flutamide.

Journal: Acta histochemica 20110901

Title: A randomized trial (Irish clinical oncology research group 97-01) comparing short versus protracted neoadjuvant hormonal therapy before radiotherapy for localized prostate cancer.

Journal: International journal of radiation oncology, biology, physics 20110901

Title: Relationship between CYP1A induction by indole-3-carbinol or flutamide and liver tumor-promoting potential in rats.

Journal: Archives of toxicology 20110901

Title: Side-effects of post-treatment biopsies in prostate cancer patients treated with endocrine therapy alone or combined with radical radiotherapy in the Scandinavian Prostate Cancer Group-7 randomized trial.

Journal: Scandinavian journal of urology and nephrology 20110901

Title: Short-term exposure to a treated sewage effluent alters reproductive behaviour in the three-spined stickleback (Gasterosteus aculeatus).

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20110901

Title: Non-migratory stonechats show seasonal changes in the hormonal regulation of non-seasonal territorial aggression.

Journal: Hormones and behavior 20110901

Title: [The regulation of T3 on maldeveloped gonocyte (Go) and expression of NCAM in flutamide-induced cryptorchidism rat].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20110901

Title: Recent adverse trends in semen quality and testis cancer incidence among Finnish men.

Journal: International journal of andrology 20110801

Title: Effect of flutamide and two novel synthetic steroids on GABA, glutamine and some oxidative stress markers in rat brain and prostate.

Journal: Andrologia 20110801

Title: Development of a highly sensitive cytotoxicity assay system for CYP3A4-mediated metabolic activation.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110801

Title: Chemical genomics profiling of environmental chemical modulation of human nuclear receptors.

Journal: Environmental health perspectives 20110801

Title: Aldol derivatives of Thioxoimidazolidinones as potential anti-prostate cancer agents.

Journal: European journal of medicinal chemistry 20110801

Title: Assessment of combinations of antiandrogenic compounds vinclozolin and flutamide in a yeast based reporter assay.

Journal: Regulatory toxicology and pharmacology : RTP 20110801

Title: Female tail wagging enhances sexual performance in male goats.

Journal: Hormones and behavior 20110801

Title: Polymer swelling, drug mobilization and drug recrystallization in hydrating solid dispersion tablets studied by multinuclear NMR microimaging and spectroscopy.

Journal: Molecular pharmaceutics 20110801

Title: Structural changes and immunohistochemical localisation of epidermal growth factor receptor in the true vocal fold of female albino rats administered anabolic, androgenic steroids, and effects of anti-androgen therapy.

Journal: The Journal of laryngology and otology 20110801

Title: The effects of testosterone on craniosynostotic calvarial cells: a test of the gene/environmental model of craniofacial anomalies.

Journal: Orthodontics & craniofacial research 20110801

Title: Androgen and estrogen receptor expression in the spinal segments of the genitofemoral nerve during testicular descent.

Journal: Journal of pediatric surgery 20110801

Title: Pharmacogenetics of glucocorticoid replacement could optimize the treatment of congenital adrenal hyperplasia due to 21-hydroxylase deficiency.

Journal: Clinics (Sao Paulo, Brazil) 20110801

Title: An assessment of androgenic/anti-androgenic effects of GH transgenic carp by Hershberger assay.

Journal: Biomedical and environmental sciences : BES 20110801

Title: [Spontaneous complete remission in two patients with chronic lymphocytic leukemia].

Journal: Medicina clinica 20110723

Title: Radiotherapy and short-term androgen deprivation for localized prostate cancer.

Journal: The New England journal of medicine 20110714

Title: Lyophilization monophase solution technique for preparation of amorphous flutamide dispersions.

Journal: Drug development and industrial pharmacy 20110701

Title: Resonance Rayleigh scattering, second-order scattering and frequency doubling scattering spectra of copper(II)-Flutamide system with anionic surfactants and its analytical application.

Journal: Journal of fluorescence 20110701

Title: Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110701

Title: Identification strategy for unknown pollutants using high-resolution mass spectrometry: androgen-disrupting compounds identified through effect-directed analysis.

Journal: Analytical and bioanalytical chemistry 20110701

Title: A molecular and phenotypic integrative approach to identify a no-effect dose level for antiandrogen-induced testicular toxicity.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110701

Title: Effects of testosterone on renal function in salt-loaded rats.

Journal: The American journal of the medical sciences 20110701

Title: Testosterone modulation of cardiac β-adrenergic signals in a rat model of heart failure.

Journal: General and comparative endocrinology 20110701

Title: A melanocortin receptor 1 and 5 antagonist inhibits sebaceous gland differentiation and the production of sebum-specific lipids.

Journal: Journal of dermatological science 20110701

Title: Sperm storage in the female reproductive tract of Scotophilus heathii: role of androgen.

Journal: Molecular reproduction and development 20110701

Title: The methoxychlor metabolite, HPTE, inhibits rat luteal cell progesterone production.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20110701

Title: Efficacy of alternative antiandrogen therapy for prostate cancer that relapsed after initial maximum androgen blockade.

Journal: Korean journal of urology 20110701

Title: Biopolymeric microparticles combined with lyophilized monophase dispersions for controlled flutamide release.

Journal: International journal of pharmaceutics 20110615

Title: The expression of FSH receptor (FSHR) in the neonatal porcine ovary and its regulation by flutamide.

Journal: Reproduction in domestic animals = Zuchthygiene 20110601

Title: The culinary-medicinal mushroom Coprinus comatus as a natural antiandrogenic modulator.

Journal: Integrative cancer therapies 20110601

Title: DDT and malaria prevention: addressing the paradox.

Journal: Environmental health perspectives 20110601

Title: Widely used pesticides with previously unknown endocrine activity revealed as in vitro antiandrogens.

Journal: Environmental health perspectives 20110601

Title: Blockade of androgen receptor in the medial amygdala inhibits noncontact erections in male rats.

Journal: Physiology & behavior 20110601

Title: Androgen receptors in the posterior bed nucleus of the stria terminalis increase neuropeptide expression and the stress-induced activation of the paraventricular nucleus of the hypothalamus.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20110601

Title: Testosterone relaxes abdominal aorta in male Sprague-Dawley rats by opening potassium (K(+)) channel and blockade of calcium (Ca(2+)) channel.

Journal: Pathophysiology : the official journal of the International Society for Pathophysiology 20110601

Title: Selenoprotein-P is down-regulated in prostate cancer, which results in lack of protection against oxidative damage.

Journal: The Prostate 20110601

Title: [Alternative antiandrogen therapy with flutamide in patients with castration-resistant prostate cancer : a single center experience].

Journal: Hinyokika kiyo. Acta urologica Japonica 20110601

Title: Clinical Characteristics of Microscopic Colitis in Korea: Prospective Multicenter Study by KASID.

Journal: Gut and liver 20110601

Title: Residual prostate cancer in patients treated with endocrine therapy with or without radical radiotherapy: a side study of the SPCG-7 randomized trial.

Journal: International journal of radiation oncology, biology, physics 20110501

Title: CYP2C9-mediated metabolic activation of losartan detected by a highly sensitive cell-based screening assay.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110501

Title: In vitro toxicity profiling of ultrapure non-dioxin-like polychlorinated biphenyl congeners and their relative toxic contribution to PCB mixtures in humans.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110501

Title: Two panels of steroid receptor luciferase reporter cell lines for compound profiling.

Journal: Combinatorial chemistry & high throughput screening 20110501

Title: Prenatal programming by testosterone of hypothalamic metabolic control neurones in the ewe.

Journal: Journal of neuroendocrinology 20110501

Title: Short-term neoadjuvant androgen deprivation and radiotherapy for locally advanced prostate cancer: 10-year data from the TROG 96.01 randomised trial.

Journal: The Lancet. Oncology 20110501

Title: Mandibular and femoral growth alteration after sex hormone disruption in growing mice.

Journal: Orthodontics & craniofacial research 20110501

Title: Treatment of female pattern hair loss with the androgen receptor antagonist flutamide.

Journal: The Australasian journal of dermatology 20110501

Title: Drug safety is a barrier to the discovery and development of new androgen receptor antagonists.

Journal: The Prostate 20110401

Title: Many putative endocrine disruptors inhibit prostaglandin synthesis.

Journal: Environmental health perspectives 20110401

Title: Neurotoxic properties of the anabolic androgenic steroids nandrolone and methandrostenolone in primary neuronal cultures.

Journal: Journal of neuroscience research 20110401

Title: Flutamide for androgen excess: low dose is best.

Journal: Journal of pediatric and adolescent gynecology 20110401

Title: Lyophilized flutamide dispersions with polyols and amino acids: preparation and in vitro evaluation.

Journal: Drug development and industrial pharmacy 20110401

Title: Prospective cohort study on the effects and tolerability of flutamide in patients with female pattern hair loss.

Journal: The Annals of pharmacotherapy 20110401

Title: Testosterone dependent androgen receptor stabilization and activation of cell proliferation in primary human myometrial microvascular endothelial cells.

Journal: Fertility and sterility 20110315

Title: Divergent effects of ethinylestradiol-drospirenone and flutamide-metformin on follistatin in adolescents and women with hyperinsulinemic androgen excess.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20110301

Title: Serum testosterone level to predict the efficacy of sequential use of antiandrogens as second-line treatment following androgen deprivation monotherapy in patients with castration-resistant prostate cancer.

Journal: Japanese journal of clinical oncology 20110301

Title: The mitogenic effect of testosterone and 17β-estradiol on airway smooth muscle cells.

Journal: Steroids 20110301

Title: Pharmacological evidence that Ca²+ channels and, to a lesser extent, K+ channels mediate the relaxation of testosterone in the canine basilar artery.

Journal: Steroids 20110301

Title: Hydroxyflutamide enhances cellular sensitivity to 5-fluorouracil by suppressing thymidylate synthase expression in bicalutamide-resistant human prostate cancer cells.

Journal: International journal of oncology 20110301

Title: Castration-resistant prostate cancer: targeted therapies and individualized treatment.

Journal: The oncologist 20110301

Title: QSAR models for anti-androgenic effect--a preliminary study.

Journal: SAR and QSAR in environmental research 20110301

Title: Current treatment strategies for castration-resistant prostate cancer.

Journal: Korean journal of urology 20110301

Title: [Establishment of a rat model of flutamide-induced cryptorchidism with remaining gonocytes].

Journal: Zhonghua nan ke xue = National journal of andrology 20110301

Title: Saudi Oncology Society clinical management guidelines for prostate cancer.

Journal: Urology annals 20110301

Title: A multi-centre randomised phase III trial of Dexamethasone vs Dexamethasone and diethylstilbestrol in castration-resistant prostate cancer: immediate vs deferred Diethylstilbestrol.

Journal: British journal of cancer 20110215

Title: Postnatal blockade of androgen receptors or aromatase impair the expression of stress hypothalamic-pituitary-adrenal axis habituation in adult male rats.

Journal: Psychoneuroendocrinology 20110201

Title: Production of human metabolites of the anti-cancer drug flutamide via biotransformation in Cunninghamella species.

Journal: Biotechnology letters 20110201

Title: The anti-androgen combination, flutamide plus finasteride, paradoxically suppressed LH and androgen concentrations in pregnant spotted hyenas, but not in males.

Journal: General and comparative endocrinology 20110201

Title: Proliferative and androgenic effects of indirubin derivatives in LNCaP human prostate cancer cells at sub-apoptotic concentrations.

Journal: Chemico-biological interactions 20110201

Title: Testosterone augments polyphenol-induced DNA damage response in prostate cancer cell line, LNCaP.

Journal: Cancer science 20110201

Title: Testosterone is involved in mediating the effects of prenatal stress in male guinea pig offspring.

Journal: The Journal of physiology 20110201

Title: Arachidonic acid pathway members PLA2G7, HPGD, EPHX2, and CYP4F8 identified as putative novel therapeutic targets in prostate cancer.

Journal: The American journal of pathology 20110201

Title: [Hormone therapy of locally advanced cancer of the prostate validated by several randomized trials].

Journal: Bulletin du cancer 20110201

Title: Gene expression profiling of the androgen receptor antagonists flutamide and vinclozolin in zebrafish (Danio rerio) gonads.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20110125

Title: Arylpiperazines for management of benign prostatic hyperplasia: design, synthesis, quantitative structure-activity relationships, and pharmacokinetic studies.

Journal: Journal of medicinal chemistry 20110113

Title: Connexin 43 gene expression in male and female gonads of porcine offspring following in utero exposure to an anti-androgen, flutamide.

Journal: Acta histochemica 20110101

Title: Sex differences in the analgesic effects of ICI 182,780 and Flutamide on ureteral calculosis in rats.

Journal: Hormones and behavior 20110101

Title: Altered expression and localization of estrogen receptors alpha and beta in the testes of a cryptorchid rat model.

Journal: Urology 20110101

Title: Procyanidin B3, an inhibitor of histone acetyltransferase, enhances the action of antagonist for prostate cancer cells via inhibition of p300-dependent acetylation of androgen receptor.

Journal: The Biochemical journal 20110101

Title: Copulatory efficiency and fertility in male rats exposed perinatally to flutamide.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20110101

Title: Prenatal and neonatal exposure to the antiandrogen flutamide alters connexin 43 gene expression in adult porcine ovary.

Journal: Domestic animal endocrinology 20110101

Title: Effect of trenbolone acetate on protein synthesis and degradation rates in fused bovine satellite cell cultures.

Journal: Domestic animal endocrinology 20110101

Title: Combined androgen blockade for prostate cancer: review of efficacy, safety and cost-effectiveness.

Journal: Cancer science 20110101

Title: Immunomodulation in polytrauma and polymicrobial sepsis - where do we stand?

Journal: Recent patents on inflammation & allergy drug discovery 20110101

Title: The American Diabetes Association's 57th annual advanced postgraduate course: diabetes risk, vitamin D, polycystic ovary syndrome, and obstructive sleep apnea.

Journal: Diabetes care 20110101

Title: Prognostic factors for failure after prostatectomy.

Journal: Journal of Cancer 20110101

Title: Acute and fulminant hepatitis induced by flutamide: case series report and review of the literature.

Journal: Annals of hepatology 20110101

Title: Experimental trauma models: an update.

Journal: Journal of biomedicine & biotechnology 20110101

Title: Hormone replacement therapy in morphine-induced hypogonadic male chronic pain patients.

Journal: Reproductive biology and endocrinology : RB&E 20110101

Title: Treatment options for polycystic ovary syndrome.

Journal: International journal of women's health 20110101

Title: Morphological and functional alterations in adult boar epididymis: Effects of prenatal and postnatal administration of flutamide.

Journal: Acta veterinaria Scandinavica 20110101

Title: Neoadjuvant hormonal therapy preceding radical prostatectomy for clinically localized prostate cancer: early postoperative complications and biochemical recurrence.

Journal: Korean journal of urology 20110101

Title: Enhanced proinflammatory cytokine response to bacterial lipopolysaccharide in the adult male rat after either neonatal or prepubertal ablation of biological testosterone activity.

Journal: Neuroimmunomodulation 20110101

Title: Synergy between inhibitors of androgen receptor and MEK has therapeutic implications in estrogen receptor-negative breast cancer.

Journal: Breast cancer research : BCR 20110101

Title: Sex hormones modulate salbutamol-elicited long-term relaxation in isolated bovine tracheal strips.

Journal: Pharmacology 20110101

Title: MDM2 antagonists boost antitumor effect of androgen withdrawal: implications for therapy of prostate cancer.

Journal: Molecular cancer 20110101

Title: IL-6 serum levels and production is related to an altered immune response in polycystic ovary syndrome girls with insulin resistance.

Journal: Mediators of inflammation 20110101

Title: Expression of androgen receptor splice variants in prostate cancer bone metastases is associated with castration-resistance and short survival.

Journal: PloS one 20110101

Title: Duration of androgen deprivation therapy with maximum androgen blockade for localized prostate cancer.

Journal: BMC urology 20110101

Title: Testosterone increases: sodium reabsorption, blood pressure, and renal pathology in female spontaneously hypertensive rats on a high sodium diet.

Journal: Advances in pharmacological sciences 20110101

Title: Design and evaluation of self-nanoemulsifying drug delivery system of flutamide.

Journal: Journal of young pharmacists : JYP 20110101

Title: Effect of 2-hydroxypropyl-β-cyclodextrin on solubility of sparingly soluble drug derivatives of anthranilic acid.

Journal: International journal of molecular sciences 20110101

Title: Role of TMPRSS2-ERG gene fusion in negative regulation of PSMA expression.

Journal: PloS one 20110101

Title: Sipuleucel-T for therapy of asymptomatic or minimally symptomatic, castrate-refractory prostate cancer: an update and perspective among other treatments.

Journal: OncoTargets and therapy 20110101

Title: Prenatal testosterone-induced fetal growth restriction is associated with down-regulation of rat placental amino acid transport.

Journal: Reproductive biology and endocrinology : RB&E 20110101

Title: Positive HER-2 protein expression in circulating prostate cells and micro-metastasis, resistant to androgen blockage but not diethylstilbestrol.

Journal: Indian journal of urology : IJU : journal of the Urological Society of India 20110101

Title: Peritoneal dissemination of prostate cancer due to laparoscopic radical prostatectomy: a case report.

Journal: Journal of medical case reports 20110101

Title: Modulation of androgen receptor signaling in hormonal therapy-resistant prostate cancer cell lines.

Journal: PloS one 20110101

Title: Flutamide versus a cyproterone acetate-ethinyl estradiol combination in moderate acne: a pilot randomized clinical trial.

Journal: Clinical, cosmetic and investigational dermatology 20110101

Title: Six-month gonadotropin releasing hormone (GnRH) agonist depots provide efficacy, safety, convenience, and comfort.

Journal: Cancer management and research 20110101

Title: The Hirsute woman: challenges in evaluation and management.

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20110101

Title: Murine polyomavirus virus-like particles carrying full-length human PSA protect BALB/c mice from outgrowth of a PSA expressing tumor.

Journal: PloS one 20110101

Title: Androgens as therapy for androgen receptor-positive castration-resistant prostate cancer.

Journal: Journal of biomedical science 20110101

Title: Control of prostate cancer associated with withdrawal of a supplement containing folic acid, L-methyltetrahydrofolate and vitamin B12: a case report.

Journal: Journal of medical case reports 20110101

Title: State of the Art Review: Emerging Therapies: The Use of Insulin Sensitizers in the Treatment of Adolescents with Polycystic Ovary Syndrome (PCOS).

Journal: International journal of pediatric endocrinology 20110101

Title: ZMIZ1 preferably enhances the transcriptional activity of androgen receptor with short polyglutamine tract.

Journal: PloS one 20110101

Title: Dephosphorylated NSSR1 is induced by androgen in mouse epididymis and phosphorylated NSSR1 is increased during sperm maturation.

Journal: PloS one 20110101

Title: Resistance to cancer treatment: the role of somatic genetic events and the challenges for targeted therapies.

Journal: Frontiers in pharmacology 20110101

Title: Mechanism of salutary effects of astringinin on rodent hepatic injury following trauma-hemorrhage: Akt-dependent hemeoxygenase-1 signaling pathways.

Journal: PloS one 20110101

Title: Prevalence of microscopic colitis in patients with chronic diarrhea in Egypt: a single-center study.

Journal: Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20110101

Title: Mono-(2-ethylhexyl) phthalate directly alters the expression of Leydig cell genes and CYP17 lyase activity in cultured rat fetal testis.

Journal: PloS one 20110101

Title: Metabolic complications and increased cardiovascular risks as a result of androgen deprivation therapy in men with prostate cancer.

Journal: Prostate cancer 20110101

Title: New insights into the androgen-targeted therapies and epigenetic therapies in prostate cancer.

Journal: Prostate cancer 20110101

Title: Adipokines and sexual hormones associated with the components of the metabolic syndrome in pharmacologically untreated subjects: data from the brisighella heart study.

Journal: International journal of endocrinology 20110101

Title: Expression profiling of CYP1B1 in oral squamous cell carcinoma: counterintuitive downregulation in tumors.

Journal: PloS one 20110101

Title: Effect of Turkish propolis extracts on proteome of prostate cancer cell line.

Journal: Proteome science 20110101

Title: Novel therapeutic strategies for malignant salivary gland tumors: lessons learned from breast cancer.

Journal: International journal of otolaryngology 20110101

Title: [Effects of cytokine-like polypeptide EMAP II and flutamide on the testosterone-stimulated prostate of castrated rats].

Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20110101

Title: Chemoprevention of prostate cancer: Natural compounds, antiandrogens, and antioxidants - In vivo evidence.

Journal: Journal of carcinogenesis 20110101

Title: Metabolomics reveals reduction of metabolic oxidation in women with polycystic ovary syndrome after pioglitazone-flutamide-metformin polytherapy.

Journal: PloS one 20110101

Title: Efficacy and safety of gonadotropin-releasing hormone agonists used in the treatment of prostate cancer.

Journal: Drug, healthcare and patient safety 20110101

Title: Hormones and prostate carcinogenesis: Androgens and estrogens.

Journal: Journal of carcinogenesis 20110101

Title: XMRV Discovery and Prostate Cancer-Related Research.

Journal: Advances in virology 20110101

Title: Molecular targets for radiation oncology in prostate cancer.

Journal: Frontiers in oncology 20110101

Title: A role for the androgen metabolite, 5alpha androstane 3beta, 17beta diol (3β-diol) in the regulation of the hypothalamo-pituitary-adrenal axis.

Journal: Frontiers in endocrinology 20110101

Title: Using bisphenol-a to study the onset of polycystic ovarian syndrome.

Journal: Frontiers in endocrinology 20110101

Title: Role of neuroactive steroids in the peripheral nervous system.

Journal: Frontiers in endocrinology 20110101

Title: PI3K: An Attractive Candidate for the Central Integration of Metabolism and Reproduction.

Journal: Frontiers in endocrinology 20110101

Title: Histochemistry through the years, browsing a long-established journal: novelties in traditional subjects.

Journal: European journal of histochemistry : EJH 20101221

Title: Sex differences in β-amyloid accumulation in 3xTg-AD mice: role of neonatal sex steroid hormone exposure.

Journal: Brain research 20101217

Title: Low-dose pioglitazone, flutamide, metformin plus an estro-progestagen for non-obese young women with polycystic ovary syndrome: increasing efficacy and persistent safety over 30 months.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20101201

Title: Inhibition of androgen receptor and Cdc25A phosphatase as a combination targeted therapy in molecular apocrine breast cancer.

Journal: Cancer letters 20101201

Title: Effect of androgen deprivation therapy on the expression of prostate cancer biomarkers MSMB and MSMB-binding protein CRISP3.

Journal: Prostate cancer and prostatic diseases 20101201

Title: Prenatal flutamide enhances survival in a myogenic mouse model of spinal bulbar muscular atrophy.

Journal: Neuro-degenerative diseases 20101201

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Successful drug development despite adverse preclinical findings part 2: examples.

Journal: Journal of toxicologic pathology 20101201

Title: Alterations in the developing testis transcriptome following embryonic vinclozolin exposure.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20101101

Title: Pharmacological targeting of constitutively active truncated androgen receptor by nigericin and suppression of hormone-refractory prostate cancer cell growth.

Journal: Molecular pharmacology 20101101

Title: Alternative antiandrogen therapy in patients with castration-resistant prostate cancer: a single-center experience.

Journal: International journal of urology : official journal of the Japanese Urological Association 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Testosterone-down-regulated Akt pathway during cardiac ischemia/reperfusion: a mechanism involving BAD, Bcl-2 and FOXO3a.

Journal: The Journal of surgical research 20101101

Title: Adrenocorticotropic hormone is involved in regulation of androgen synthesis in men receiving androgen deprivation therapy for localized prostate cancer.

Journal: The Journal of urology 20101101

Title: Some flame retardants and the antimicrobials triclosan and triclocarban enhance the androgenic activity in vitro.

Journal: Chemosphere 20101101

Title: Calpain activation through galectin-3 inhibition sensitizes prostate cancer cells to cisplatin treatment.

Journal: Cell death & disease 20101101

Title: Testosterone exacerbates neuronal damage following cardiac arrest and cardiopulmonary resuscitation in mouse.

Journal: Brain research 20101021

Title: The lack of estrogen and excess luteinizing hormone are responsible for the female ArKO mouse phenotype.

Journal: Molecular and cellular endocrinology 20101007

Title: Tissue changes in senescent gerbil prostate after hormone deprivation leads to acquisition of androgen insensitivity.

Journal: International journal of experimental pathology 20101001

Title: Age disrupts androgen receptor-modulated negative feedback in the gonadal axis in healthy men.

Journal: American journal of physiology. Endocrinology and metabolism 20101001

Title: Serum prostate-specific antigen levels reflect the androgen milieu in patients with localized prostate cancer receiving androgen deprivation therapy: Tumor malignant potential and androgen milieu.

Journal: The Prostate 20100915

Title: PXR-mediated induction of P-glycoprotein by anticancer drugs in a human colon adenocarcinoma-derived cell line.

Journal: Cancer chemotherapy and pharmacology 20100901

Title: Mate calling behavior of male South African clawed frogs (Xenopus laevis) is suppressed by the antiandrogenic endocrine disrupting compound flutamide.

Journal: General and comparative endocrinology 20100901

Title: Aromatase mRNA expression in the brain of adult Xenopus laevis exposed to Lambro river water and endocrine disrupting compounds.

Journal: General and comparative endocrinology 20100901

Title: Arylacetamide deacetylase is a determinant enzyme for the difference in hydrolase activities of phenacetin and acetaminophen.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100901

Title: The testosterone-derived neurosteroid androstanediol is a positive allosteric modulator of GABAA receptors.

Journal: The Journal of pharmacology and experimental therapeutics 20100901

Title: Use of chemical mixtures to differentiate mechanisms of endocrine action in a small fish model.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20100901

Title: Activity of antiandrogens against juvenile and adult Schistosoma mansoni in mice.

Journal: The Journal of antimicrobial chemotherapy 20100901

Title: Hormonal suppression restores fertility in irradiated mice from both endogenous and donor-derived stem spermatogonia.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100901

Title: Value of combined androgen blockade in the neoadjuvant treatment of localized prostate cancer: the jury must remain out.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100901

Title: Efficacy of maximal androgen blockade versus castration alone in the treatment of advanced prostate cancer: a retrospective clinical experience from a Chinese medical centre.

Journal: Asian journal of andrology 20100901

Title: Isoflurane preconditioning neuroprotection in experimental focal stroke is androgen-dependent in male mice.

Journal: Neuroscience 20100825

Title: Effects of neonatal flutamide treatment on hippocampal neurogenesis and synaptogenesis correlate with depression-like behaviors in preadolescent male rats.

Journal: Neuroscience 20100811

Title: Assessment of a recombinant androgen receptor binding assay: initial steps towards validation.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20100801

Title: Short-term dynamic culture of rat testicular fragments as a model to assess effects on steroidogenesis--potential use and limitations.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20100801

Title: Flutamide inhibits nifedipine- and interleukin-1 beta-induced collagen overproduction in gingival fibroblasts.

Journal: Journal of periodontal research 20100801

Title: Androgen receptor blockade in the posterodorsal medial amygdala impairs sexual odor preference in male rats.

Journal: Hormones and behavior 20100801

Title: Optimization and prevalidation of the in vitro AR CALUX method to test androgenic and antiandrogenic activity of compounds.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20100801

Title: Castration induces changes in the cation-dependent mannose-6-phosphate receptor in rat epididymis: possible implications in secretion of lysosomal enzymes.

Journal: Journal of cellular biochemistry 20100801

Title: Androgens regulate adenylate cyclase activity and intracellular calcium in stromal cells derived from human prostate.

Journal: The Prostate 20100801

Title: Therapy: Low-dose flutamide for hirsutism: into the limelight, at last.

Journal: Nature reviews. Endocrinology 20100801

Title: Words of wisdom. Re: Does oral antiandrogen use before leuteinizing hormone-releasing therapy in patients with metastatic prostate cancer prevent clinical consequences of a testosterone flare? Oh WK, Landrum MB, Lamont EB, et al. Urology 2010;75:642-7.

Journal: European urology 20100801

Title: Radiation with or without 6 months of androgen suppression therapy in intermediate- and high-risk clinically localized prostate cancer: a postrandomization analysis by risk group.

Journal: International journal of radiation oncology, biology, physics 20100715

Title: Intramolecular charge transfer effects on flutamide drug.

Journal: Journal of fluorescence 20100701

Title: A transcriptomics-based biological framework for studying mechanisms of endocrine disruption in small fish species.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20100701

Title: Retrospective observational study on the effects and tolerability of flutamide in a large population of patients with various kinds of hirsutism over a 15-year period.

Journal: European journal of endocrinology 20100701

Title: Dysregulation of leptin and testosterone production and their receptor expression in the human placenta with gestational diabetes mellitus.

Journal: Placenta 20100701

Title: Mitogen-activated protein kinases pathway is involved in physiological testosterone-induced tissue factor pathway inhibitor expression in endothelial cells.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20100701

Title: Differential actions of eplerenone and spironolactone on the protective effect of testosterone against cardiomyocyte apoptosis in vitro.

Journal: Revista espanola de cardiologia 20100701

Title: Effects and mechanisms of progestogens and androgens in ictal activity.

Journal: Epilepsia 20100701

Title: Embryonic expression of the cysteine rich protein 61 (CYR61) gene: A candidate for the development of human epispadias.

Journal: Birth defects research. Part A, Clinical and molecular teratology 20100701

Title: Specific in vitro toxicity of crude and refined petroleum products: II. Estrogen (alpha and beta) and androgen receptor-mediated responses in yeast assays.

Journal: Environmental toxicology and chemistry 20100701

Title: Effects of pre- and postnatal exposure to flutamide on connexin 43 expression in testes and ovaries of prepubertal pigs.

Journal: European journal of histochemistry : EJH 20100614

Title: Short-term antiandrogen flutamide treatment causes structural alterations in somatic cells associated with premature detachment of spermatids in the testis of pubertal and adult guinea pigs.

Journal: Reproduction in domestic animals = Zuchthygiene 20100601

Title: Management of acne vulgaris: an evidence-based update.

Journal: Clinical and experimental dermatology 20100601

Title: Blockade of androgen or estrogen receptors reduces nandrolone's ability to modulate acute reward-related neurochemical effects of amphetamine in rat brain.

Journal: Pharmacology, biochemistry, and behavior 20100601

Title: Prenatal exposure to vinclozolin disrupts selective aspects of the gonadotrophin-releasing hormone neuronal system of the rabbit.

Journal: Journal of neuroendocrinology 20100601

Title: Prenatal plus postnatal exposure to Di(n-Butyl) phthalate and/or flutamide markedly reduces final sertoli cell number in the rat.

Journal: Endocrinology 20100601

Title: A selective androgen receptor modulator enhances male-directed sexual preference, proceptive behavior, and lordosis behavior in sexually experienced, but not sexually naive, female rats.

Journal: Endocrinology 20100601

Title: Spermatogenesis after 1-stage fowler-stephens orchiopexy in experimental cryptorchid rat model.

Journal: The Journal of urology 20100601

Title: Duration of first off-treatment interval is prognostic for time to castration resistance and death in men with biochemical relapse of prostate cancer treated on a prospective trial of intermittent androgen deprivation.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100601

Title: Determination of 2-hydroxyflutamide in human plasma by liquid chromatography-tandem mass spectrometry (LC-MS/MS): application to a bioequivalence study on Chinese volunteers.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100601

Title: Androgens and spermatogenesis: lessons from transgenic mouse models.

Journal: Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20100527

Title: Progression to metastatic stage in a cellular model of prostate cancer is associated with methylation of the androgen receptor gene and transcriptional suppression of the insulin-like growth factor-I receptor gene.

Journal: Experimental cell research 20100515

Title: Risk of thromboembolic diseases in men with prostate cancer: results from the population-based PCBaSe Sweden.

Journal: The Lancet. Oncology 20100511

Title: OECD validation of phase-3 Hershberger assay using the stimulated weanling male rat in Korea.

Journal: Journal of applied toxicology : JAT 20100501

Title: Correlates of trabecular and cortical volumetric bone mineral density of the radius and tibia in older men: the Osteoporotic Fractures in Men Study.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20100501

Title: A mouse model of androgenetic alopecia.

Journal: Endocrinology 20100501

Title: Is the 'comb over' dying? A mouse model for male pattern baldness (androgenic alopecia).

Journal: Endocrinology 20100501

Title: Effects of flutamide therapy on craniofacial growth and development in a model of craniosynostosis.

Journal: The Journal of craniofacial surgery 20100501

Title: [Membrane testosterone receptors in cultured vascular smooth muscle cells].

Journal: Zhonghua nan ke xue = National journal of andrology 20100501

Title: Gonadotropin-regulated testicular RNA helicase (GRTH/DDX25) gene: cell-specific expression and transcriptional regulation by androgen in transgenic mouse testis.

Journal: Journal of cellular biochemistry 20100415

Title: An in vitro drug-induced hepatotoxicity screening system using CYP3A4-expressing and gamma-glutamylcysteine synthetase knockdown cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100401

Title: Androgen action in the masculinization programming window and development of male reproductive organs.

Journal: International journal of andrology 20100401

Title: Mixture effects of endocrine disrupting compounds in vitro.

Journal: International journal of andrology 20100401

Title: The role of RXFP2 in mediating androgen-induced inguinoscrotal testis descent in LH receptor knockout mice.

Journal: Reproduction (Cambridge, England) 20100401

Title: Adrenal androgen levels as predictors of outcome in castration-resistant prostate cancer patients treated with combined androgen blockade using flutamide as a second-line anti-androgen.

Journal: International journal of urology : official journal of the Japanese Urological Association 20100401

Title: Effect of essential oils, such as raspberry ketone and its derivatives, on antiandrogenic activity based on in vitro reporter gene assay.

Journal: Bioorganic & medicinal chemistry letters 20100401

Title: Dioxin-induced changes in epididymal sperm count and spermatogenesis.

Journal: Environmental health perspectives 20100401

Title: Microbial metabolism. Part 11. Metabolites of flutamide.

Journal: Chemical & pharmaceutical bulletin 20100401

Title: Morphology of the cockerel's comb after androgen administration.

Journal: British poultry science 20100401

Title: Synthesis and biodistribution of [99mTc]-N-[4-nitro-3-trifluoromethyl-phenyl] cyclopentadienyltricarbonyltechnetium carboxamide, a nonsteroidal antiandrogen flutamide derivative.

Journal: Metallomics : integrated biometal science 20100401

Title: Androgen receptor-dependent transactivation of growth arrest-specific gene 6 mediates inhibitory effects of testosterone on vascular calcification.

Journal: The Journal of biological chemistry 20100305

Title: Aquaporin 9 expression in the developing rat epididymis is modulated by steroid hormones.

Journal: Reproduction (Cambridge, England) 20100301

Title: The effects of beta-blockers on endothelial nitric oxide synthase immunoreactivity in the rat corpus cavernosum.

Journal: Urology 20100301

Title: Cryptic regulation of vasotocin neuronal activity but not anatomy by sex steroids and social stimuli in opportunistic desert finches.

Journal: Brain, behavior and evolution 20100301

Title: [Hormonal antiandrogens in acne treatment].

Journal: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20100301

Title: 'Click' labeling strategy for M(CO)(3) (M = Re, (99m)Tc) prostate cancer targeted flutamide agents.

Journal: Dalton transactions (Cambridge, England : 2003) 20100227

Title: Study of the impact of the T877A mutation on ligand-induced helix-12 positioning of the androgen receptor resulted in design and synthesis of novel antiandrogens.

Journal: Proteins 20100215

Title: Antiandrogen withdrawal syndrome and alternative antiandrogen therapy associated with the W741C mutant androgen receptor in a novel prostate cancer xenograft.

Journal: The Prostate 20100215

Title: Systematic structure-function analysis of androgen receptor Leu701 mutants explains the properties of the prostate cancer mutant L701H.

Journal: The Journal of biological chemistry 20100212

Title: C/EBPalpha redirects androgen receptor signaling through a unique bimodal interaction.

Journal: Oncogene 20100204

Title: Metastasis of genitourinary tumors to the head and neck region.

Journal: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20100201

Title: Critical androgen-sensitive periods of rat penis and clitoris development.

Journal: International journal of andrology 20100201

Title: Up-regulation of circadian clock gene Period 2 in the prostate mesenchymal cells during flutamide-induced apoptosis.

Journal: Molecular and cellular biochemistry 20100201

Title: Bone metabolic disorder in patients with prostate cancer receiving androgen deprivation therapy (ADT): impact of ADT on the growth hormone/insulin-like growth factor-1/parathyroid hormone axis.

Journal: The Prostate 20100201

Title: Androgenic regulation of ventral epithelial bud number and pattern in mouse urogenital sinus.

Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20100201

Title: Lyophilization monophase solution technique for improvement of the physicochemical properties of an anticancer drug, flutamide.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20100201

Title: Functional remodeling of benign human prostatic tissues in vivo by spontaneously immortalized progenitor and intermediate cells.

Journal: Stem cells (Dayton, Ohio) 20100201

Title: Regulation of heat shock protein 70-1 expression by androgen receptor and its signaling in human prostate cancer cells.

Journal: International journal of oncology 20100201

Title: Anti-androgen treatments.

Journal: Annales d'endocrinologie 20100201

Title: Hidden in plain sight: the mammary line in males may be the missing link regulating inguinoscrotal testicular descent.

Journal: Journal of pediatric surgery 20100201

Title: The aromatase inhibitor 1,4,6-androstatriene-3,17-dione (ATD) reduces disinhibitory behavior in intact adult male rats treated with a high dose of testosterone.

Journal: Behavioural brain research 20100120

Title: Acute 19-nortestosterone transiently suppresses hippocampal MAPK pathway and the phosphorylation of the NMDA receptor.

Journal: Molecular and cellular endocrinology 20100115

Title: Prostate stem cell antigen enhancer and uroplakin II promoter based bladder cancer targeted tissue-specific vector.

Journal: Urologic oncology 20100101

Title: Is biochemical response more important than duration of neoadjuvant hormone therapy before radiotherapy for clinically localized prostate cancer? An analysis of the 3- versus 8-month randomized trial.

Journal: International journal of radiation oncology, biology, physics 20100101

Title: Long-term follow-up of 3-month neoadjuvant hormone therapy before radical prostatectomy in a randomized trial.

Journal: BJU international 20100101

Title: Changes in gene expression in somatic cells of rat testes resulting from hormonal modulation and radiation-induced germ cell depletion.

Journal: Biology of reproduction 20100101

Title: The role of androgen receptors in regulating territorial aggression in male song sparrows.

Journal: Hormones and behavior 20100101

Title: Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors.

Journal: Reproduction (Cambridge, England) 20100101

Title: Does the cranial suspensory ligament have a role in cryptorchidism?

Journal: Cells, tissues, organs 20100101

Title: Gene expression profile of androgen modulated genes in the murine fetal developing lung.

Journal: Reproductive biology and endocrinology : RB&E 20100101

Title: Hormonal therapy for acne: why not as first line therapy? facts and controversies.

Journal: Clinics in dermatology 20100101

Title: Growth inhibition of androgen-responsive prostate cancer cells with brefeldin A targeting cell cycle and androgen receptor.

Journal: Journal of biomedical science 20100101

Title: Analysis of the molecular networks in androgen dependent and independent prostate cancer revealed fragile and robust subsystems.

Journal: PloS one 20100101

Title: Growth and reproductive outcomes in congenital adrenal hyperplasia.

Journal: International journal of pediatric endocrinology 20100101

Title: Age-dependent role of steroids in the regulation of growth of the hen follicular wall.

Journal: Reproductive biology and endocrinology : RB&E 20100101

Title: A randomized phase II trial of mitoxantrone, estramustine and vinorelbine or bcl-2 modulation with 13-cis retinoic acid, interferon and paclitaxel in patients with metastatic castrate-resistant prostate cancer: ECOG 3899.

Journal: Journal of translational medicine 20100101

Title: Lymphocytic colitis presenting as difficult diarrhoea in an African woman: a case report and review of the literature.

Journal: Journal of medical case reports 20100101

Title: Exploring the antiperoxidative potential of morin on cyclophosphamide and flutamide-induced lipid peroxidation and changes in cholesterol profile in rabbit model.

Journal: Acta poloniae pharmaceutica 20100101

Title: An Evidence-Based Model of Multidisciplinary Care for Patients and Families Affected by Classical Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency.

Journal: International journal of pediatric endocrinology 20100101

Title: Testosterone depletion by castration may protect mice from heat-induced multiple organ damage and lethality.

Journal: Journal of biomedicine & biotechnology 20100101

Title: The evolutionary impact of androgen levels on prostate cancer in a multi-scale mathematical model.

Journal: Biology direct 20100101

Title: Hirsutism: evaluation and treatment.

Journal: Indian journal of dermatology 20100101

Title: Radiolabeling, biodistribution and gamma scintigraphy of noscapine hydrochloride in normal and polycystic ovary induced rats.

Journal: Journal of ovarian research 20100101

Title: WNT4/beta-catenin pathway maintains female germ cell survival by inhibiting activin betaB in the mouse fetal ovary.

Journal: PloS one 20100101

Title: Maximal androgen blockade for advanced prostate cancer.

Journal: Indian journal of urology : IJU : journal of the Urological Society of India 20100101

Title: The changes of cortactin p80/85 isoform profiles and tyrosine phosphorylation status during spermatogenesis in the mouse testis.

Journal: Journal of andrology 20100101

Title: Hormonal therapy of prostate cancer.

Journal: Progress in brain research 20100101

Title: 3alpha-androstanediol, but not testosterone, attenuates age-related decrements in cognitive, anxiety, and depressive behavior of male rats.

Journal: Frontiers in aging neuroscience 20100101

Title: Androgen excess produces systemic oxidative stress and predisposes to beta-cell failure in female mice.

Journal: PloS one 20100101

Title: Management of the adult with congenital adrenal hyperplasia.

Journal: International journal of pediatric endocrinology 20100101

Title: Update on options for treatment of metastatic castration-resistant prostate cancer.

Journal: OncoTargets and therapy 20100101

Title: Alternative strategies for the treatment of classical congenital adrenal hyperplasia: pitfalls and promises.

Journal: International journal of pediatric endocrinology 20100101

Title: Nonclassic congenital adrenal hyperplasia.

Journal: International journal of pediatric endocrinology 20100101

Title: Is there an optimal management for localized prostate cancer?

Journal: Clinical interventions in aging 20100101

Title: Integrating GHS into the Ghrelin System.

Journal: International journal of peptides 20100101

Title: Endocrine disruptors and Leydig cell function.

Journal: Journal of biomedicine & biotechnology 20100101

Title: Effects of in utero exposure to DI(n-Butyl) phthalate on development of male reproductive tracts in Sprague-Dawley rats.

Journal: Journal of toxicology and environmental health. Part A 20100101

Title: Bypass mechanisms of the androgen receptor pathway in therapy-resistant prostate cancer cell models.

Journal: PloS one 20100101

Title: Impact of hormonal treatment duration in combination with radiotherapy for locally advanced prostate cancer: meta-analysis of randomized trials.

Journal: BMC cancer 20100101

Title: Testosterone and cholesterol vasodilation of rat aorta involves L-type calcium channel inhibition.

Journal: Advances in pharmacological sciences 20100101

Title: Effectiveness of long-term (twelve months) nonsurgical weight loss interventions for obese women with polycystic ovary syndrome: a systematic review.

Journal: International journal of women's health 20100101

Title: Characterization of the small RNA transcriptomes of androgen dependent and independent prostate cancer cell line by deep sequencing.

Journal: PloS one 20100101

Title: Down-regulation of phosphoglucomutase 3 mediates sulforaphane-induced cell death in LNCaP prostate cancer cells.

Journal: Proteome science 20100101

Title: Endocrinology of hirsutism.

Journal: International journal of trichology 20100101

Title: Evaluation of degarelix in the management of prostate cancer.

Journal: Cancer management and research 20100101

Title: Radiotherapy combined with hormonal therapy in prostate cancer: the state of the art.

Journal: Cancer management and research 20100101

Title: Changes of androgen receptor and insulin-like growth factor-1 in LNCaP prostate cancer cells treated with sex hormones and flutamide.

Journal: Asian Pacific journal of cancer prevention : APJCP 20100101

Title: Effect of Buddleia flavonoids drug-containing plasma on the expression of STAT1 phosphoprotein in lacrimal gland epithelial cells in vitro.

Journal: International journal of ophthalmology 20100101

Title: Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.

Journal: Journal of medicinal chemistry 20091210

Title: Androgen receptor antagonism and an insulin sensitizer block the advancement of vaginal opening by high-fat diet in mice.

Journal: Biology of reproduction 20091201

Title: Comparison of in vitro hormone activities of selected phthalates using reporter gene assays.

Journal: Toxicology letters 20091201

Title: Evaluation of the potential for drug-induced liver injury based on in vitro covalent binding to human liver proteins.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20091201

Title: Androgens induce dopaminergic neurotoxicity via caspase-3-dependent activation of protein kinase Cdelta.

Journal: Endocrinology 20091201

Title: The antiandrogen flutamide perturbs inguinoscrotal testicular descent in the rat and suggests a link with mammary development.

Journal: Journal of pediatric surgery 20091201

Title: Gynecomastia: An ADR due to drug interaction.

Journal: Indian journal of pharmacology 20091201

Title: [Activity induced by androsterone and hemisuccinate of androsterone on perfusion pressure and vascular resistance].

Journal: Biomedica : revista del Instituto Nacional de Salud 20091201

Title: Synthesis, structure-activity relationships, and characterization of novel nonsteroidal and selective androgen receptor modulators.

Journal: Journal of medicinal chemistry 20091126

Title: Relevance of an opioid, noscapine in reducing cystogeneses in rat experimental model of polycystic ovary syndrome.

Journal: Journal of endocrinological investigation 20091101

Title: A novel androgen-dependent prostate cancer xenograft model derived from skin metastasis of a Japanese patient.

Journal: The Prostate 20091101

Title: Prostate cancer survivorship: prevention and treatment of the adverse effects of androgen deprivation therapy.

Journal: Journal of general internal medicine 20091101

Title: Antiseizure effects of 3alpha-androstanediol and/or 17beta-estradiol may involve actions at estrogen receptor beta.

Journal: Epilepsy & behavior : E&B 20091101

Title: Basic exploratory research versus guideline-compliant studies used for hazard evaluation and risk assessment: bisphenol A as a case study.

Journal: Environmental health perspectives 20091101

Title: Anogenital distance from birth to 2 years: a population study.

Journal: Environmental health perspectives 20091101

Title: Metabolomics in drug intolerance.

Journal: Current drug metabolism 20091101

Title: Phase II trial of short-term neoadjuvant docetaxel and complete androgen blockade in high-risk prostate cancer.

Journal: British journal of cancer 20091020

Title: Neuroprotective effects of testosterone upon cardiac sympathetic function in rats with induced heart failure.

Journal: European journal of pharmacology 20091001

Title: Dehydroepiandrosterone inhibits the proliferation and induces the death of HPV-positive and HPV-negative cervical cancer cells through an androgen- and estrogen-receptor independent mechanism.

Journal: The FEBS journal 20091001

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Sex steroids are necessary in the second postnatal week for the expression of male alloparental behavior in prairie voles (Microtus ochragaster).

Journal: Behavioral neuroscience 20091001

Title: Testosterone inhibits the activity of peroxisome proliferator-activated receptor gamma in a transcriptional transaction assay.

Journal: Die Pharmazie 20091001

Title: Androgen-mediated apoptosis of kidney tubule cells: role of c-Jun amino terminal kinase.

Journal: Biochemical and biophysical research communications 20090925

Title: Drug-induced hepatotoxicity test using gamma-glutamylcysteine synthetase knockdown rat.

Journal: Toxicology letters 20090910

Title: Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells.

Journal: Blood 20090910

Title: Low-dose pioglitazone and low-dose flutamide added to metformin and oestro-progestagens for hyperinsulinaemic women with androgen excess: add-on benefits disclosed by a randomized double-placebo study over 24 months.

Journal: Clinical endocrinology 20090901

Title: Genitourinary toxicity after high-dose-rate (HDR) brachytherapy combined with Hypofractionated External beam radiotherapy for localized prostate cancer: an analysis to determine the correlation between dose-volume histogram parameters in HDR brachytherapy and severity of toxicity.

Journal: International journal of radiation oncology, biology, physics 20090901

Title: Long-term effects of intermittent androgen suppression on testosterone recovery and bone mineral density: results of a 33-month observational study.

Journal: BJU international 20090901

Title: Radiation dose predicts for biochemical control in intermediate-risk prostate cancer patients treated with low-dose-rate brachytherapy.

Journal: International journal of radiation oncology, biology, physics 20090901

Title: Interval to testosterone recovery after hormonal therapy for prostate cancer and risk of death.

Journal: International journal of radiation oncology, biology, physics 20090901

Title: Effects of estrogen and androgen deprivation on the progression of non-alcoholic steatohepatitis (NASH) in male Sprague-Dawley rats.

Journal: Hepatology research : the official journal of the Japan Society of Hepatology 20090901

Title: Establishment of knockdown of superoxide dismutase 2 and expression of CYP3A4 cell system to evaluate drug-induced cytotoxicity.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20090901

Title: The prostate growth stimulation by progesterone is due to androgenic products and progesterone receptor-mediated mechanisms.

Journal: Die Pharmazie 20090901

Title: Characterization of the intra-prostatic immune cell infiltration in androgen-deprived prostate cancer patients.

Journal: Journal of immunological methods 20090831

Title: Evaluation of the rodent Hershberger bioassay on intact juvenile males--testing of coded chemicals and supplementary biochemical investigations.

Journal: Toxicology 20090803

Title: Combined low-dose flutamide plus finasteride vs low-dose flutamide monotherapy for recurrent prostate cancer: a comparative analysis of two phase II trials with a long-term follow-up.

Journal: BJU international 20090801

Title: Differential effects of flutamide and di-(2-ethylhexyl) phthalate on male reproductive organs in a rat model.

Journal: The Journal of reproduction and development 20090801

Title: Dose-dependent effects of androgens on outcome after focal cerebral ischemia in adult male mice.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090801

Title: Androgen- and estrogen-independent regulation of copulatory behavior following castration in male B6D2F1 mice.

Journal: Hormones and behavior 20090801

Title: Endocrine-disrupting equivalents in industrial effluents discharged into Yangtze River.

Journal: Ecotoxicology (London, England) 20090801

Title: Both endogenous and exogenous testosterone decrease myocardial STAT3 activation and SOCS3 expression after acute ischemia and reperfusion.

Journal: Surgery 20090801

Title: Calcitonin gene-related peptide is a survival factor, inhibiting apoptosis in neonatal rat gubernaculum in vitro.

Journal: Journal of pediatric surgery 20090801

Title: Starving the addiction: new opportunities for durable suppression of AR signaling in prostate cancer.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090801

Title: N-myc downstream regulated gene 1 (NDRG1) is fused to ERG in prostate cancer.

Journal: Neoplasia (New York, N.Y.) 20090801

Title: Drug-induced liver disease: an 8-year study of patients from one gastroenterological department.

Journal: Journal of digestive diseases 20090801

Title: Pharmacological options for treatment of hyperandrogenic disorders.

Journal: Mini reviews in medicinal chemistry 20090801

Title: Underlying mitochondrial dysfunction triggers flutamide-induced oxidative liver injury in a mouse model of idiosyncratic drug toxicity.

Journal: Toxicology and applied pharmacology 20090715

Title: Human arylacetamide deacetylase is a principal enzyme in flutamide hydrolysis.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090701

Title: Regucalcin is under-expressed in human breast and prostate cancers: Effect of sex steroid hormones.

Journal: Journal of cellular biochemistry 20090701

Title: Masking effect of anti-androgens on androgenic activity in European river sediment unveiled by effect-directed analysis.

Journal: Analytical and bioanalytical chemistry 20090701

Title: Diarylheptanoid phytoestrogens isolated from the medicinal plant Curcuma comosa: biologic actions in vitro and in vivo indicate estrogen receptor-dependent mechanisms.

Journal: Environmental health perspectives 20090701

Title: Hepatotoxicity during low-dose flutamide treatment for hirsutism.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20090701

Title: Alternative inhibition of androgen receptor signaling: peptidomimetic pyrimidines as direct androgen receptor/coactivator disruptors.

Journal: ACS chemical biology 20090619

Title: Id-1 expression in androgen-dependent prostate cancer is negatively regulated by androgen through androgen receptor.

Journal: Cancer letters 20090618

Title: Duration of androgen suppression in the treatment of prostate cancer.

Journal: The New England journal of medicine 20090611

Title: Nuclear receptor mediated induction of cytochrome P450 3A4 by anticancer drugs: a key role for the pregnane X receptor.

Journal: Cancer chemotherapy and pharmacology 20090601

Title: Recognizing false biochemical failure calls after radiation with or without neo-adjuvant androgen deprivation for prostate cancer.

Journal: International journal of radiation oncology, biology, physics 20090601

Title: Growth differentiation factor 9 promotes rat preantral follicle growth by up-regulating follicular androgen biosynthesis.

Journal: Endocrinology 20090601

Title: Maternal exposure to anti-androgenic compounds, vinclozolin, flutamide and procymidone, has no effects on spermatogenesis and DNA methylation in male rats of subsequent generations.

Journal: Toxicology and applied pharmacology 20090601

Title: Modulation of ovarian structure and abdominal obesity in curcumin- and flutamide-treated aging FSH-R haploinsufficient mice.

Journal: Reproductive sciences (Thousand Oaks, Calif.) 20090601

Title: Androgen receptors in coeliac ganglion in late pregnant rat.

Journal: Steroids 20090601

Title: Integrating statistical predictions and experimental verifications for enhancing protein-chemical interaction predictions in virtual screening.

Journal: PLoS computational biology 20090601

Title: Detection of the anti-androgenic effect of endocrine disrupting environmental contaminants using in vivo and in vitro assays in the three-spined stickleback.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20090517

Title: Establishment of a novel immortalized human prostatic epithelial cell line stably expressing androgen receptor and its application for the functional screening of androgen receptor modulators.

Journal: Biochemical and biophysical research communications 20090515

Title: Treatment-dependent androgen receptor mutations in prostate cancer exploit multiple mechanisms to evade therapy.

Journal: Cancer research 20090515

Title: Dihydrotestosterone stimulates aldosterone secretion by H295R human adrenocortical cells.

Journal: Molecular and cellular endocrinology 20090506

Title: New insights into the role of androgens in wolffian duct stabilization in male and female rodents.

Journal: Endocrinology 20090501

Title: OECD validation of phase 3 Hershberger assay in Korea using surgically castrated male rats with coded chemicals.

Journal: Journal of applied toxicology : JAT 20090501

Title: Quantitative proteomic profiles of androgen receptor signaling in the liver of fathead minnows (Pimephales promelas).

Journal: Journal of proteome research 20090501

Title: Standard and molecular NOAELs for rat testicular toxicity induced by flutamide.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090501

Title: Suppression of mutant androgen receptors by flutamide.

Journal: International journal of urology : official journal of the Japanese Urological Association 20090501

Title: Regulation of ryanodine receptor-mediated Ca(2+) release in vas deferens smooth muscle cells.

Journal: Journal of pharmacological sciences 20090501

Title: Statistical modeling suggests that antiandrogens in effluents from wastewater treatment works contribute to widespread sexual disruption in fish living in English rivers.

Journal: Environmental health perspectives 20090501

Title: Long-term safety and tolerability of flutamide for the treatment of hirsutism.

Journal: Fertility and sterility 20090401

Title: Functional AR signaling is evident in an in vitro mouse follicle culture bioassay that encompasses most stages of folliculogenesis.

Journal: Biology of reproduction 20090401

Title: Quality of life in patients with locally advanced prostate cancer given endocrine treatment with or without radiotherapy: 4-year follow-up of SPCG-7/SFUO-3, an open-label, randomised, phase III trial.

Journal: The Lancet. Oncology 20090401

Title: Time- and dose-related effects of di-(2-ethylhexyl) phthalate and its main metabolites on the function of the rat fetal testis in vitro.

Journal: Environmental health perspectives 20090401

Title: Expression signatures for a model androgen and antiandrogen in the fathead minnow (Pimephales promelas) ovary.

Journal: Environmental science & technology 20090401

Title: [Clinical usefulness of chlormadinone acetate as an alternative antiandrogen therapy for prostate cancer relapse after combined androgen blockade therapy].

Journal: Hinyokika kiyo. Acta urologica Japonica 20090401

Title: The risk of hepatotoxicity during long-term and low-dose flutamide treatment in hirsutism.

Journal: Archives of gynecology and obstetrics 20090301

Title: Cognitive and mood changes in men undergoing intermittent combined androgen blockade for non-metastatic prostate cancer.

Journal: Psycho-oncology 20090301

Title: Age-dependent effects of testosterone in experimental stroke.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090301

Title: Hair loss in women.

Journal: Seminars in cutaneous medicine and surgery 20090301

Title: The role of androgen receptor mutations in prostate cancer progression.

Journal: Current genomics 20090301

Title: Toxicogenomic biomarkers for liver toxicity.

Journal: Journal of toxicologic pathology 20090301

Title: Potential surrogate endpoints for prostate cancer survival: analysis of a phase III randomized trial.

Journal: Journal of the National Cancer Institute 20090218

Title: N-Benzyl-1-heteroaryl-3-(trifluoromethyl)-1H-pyrazole-5-carboxamides as inhibitors of co-activator associated arginine methyltransferase 1 (CARM1).

Journal: Bioorganic & medicinal chemistry letters 20090215

Title: Final report of multicenter Canadian Phase III randomized trial of 3 versus 8 months of neoadjuvant androgen deprivation therapy before conventional-dose radiotherapy for clinically localized prostate cancer.

Journal: International journal of radiation oncology, biology, physics 20090201

Title: Dihydrotestosterone stimulates cerebrovascular inflammation through NFkappaB, modulating contractile function.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090201

Title: Twenty-four-month postradiation prostate biopsies are strongly predictive of 7-year disease-free survival: results from a Canadian randomized trial.

Journal: Cancer 20090201

Title: Androgen-induced human breast cancer cell proliferation is mediated by discrete mechanisms in estrogen receptor-alpha-positive and -negative breast cancer cells.

Journal: The Journal of steroid biochemistry and molecular biology 20090201

Title: Addressing bone loss in the cancer survivor.

Journal: Oncology (Williston Park, N.Y.) 20090201

Title: Endocrine treatment, with or without radiotherapy, in locally advanced prostate cancer (SPCG-7/SFUO-3): an open randomised phase III trial.

Journal: Lancet (London, England) 20090124

Title: Human xenograft models as useful tools to assess the potential of novel therapeutics in prostate cancer.

Journal: British journal of cancer 20090113

Title: Partial androgen suppression consequent to increased secretion of adrenal androgens in a patient with prostate cancer treated with long-acting GnRH agonists.

Journal: Prostate cancer and prostatic diseases 20090101

Title: Antiandrogen exposure in utero disrupts expression of desert hedgehog and insulin-like factor 3 in the developing fetal rat testis.

Journal: Endocrinology 20090101

Title: Role of enzymatic N-hydroxylation and reduction in flutamide metabolite-induced liver toxicity.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090101

Title: Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: a putative mechanism.

Journal: American journal of physiology. Cell physiology 20090101

Title: Neoadjuvant hormonal deprivation for patients undergoing radical prostatectomy.

Journal: Asian journal of andrology 20090101

Title: Synthesis and characterization of nonsteroidal-linked M(CO)(3)+ (M = 99mTc, Re) compounds based on the androgen receptor targeting molecule flutamide.

Journal: Bioconjugate chemistry 20090101

Title: Estrogen enhances recovery from radiation-induced spermatogonial arrest in rat testes.

Journal: Journal of andrology 20090101

Title: Phthalates impair germ cell development in the human fetal testis in vitro without change in testosterone production.

Journal: Environmental health perspectives 20090101

Title: Androgen receptor modulation does not affect longitudinal growth of cultured fetal rat metatarsal bones.

Journal: Hormone research 20090101

Title: Androgen deprivation modulates the inflammatory response induced by irradiation.

Journal: BMC cancer 20090101

Title: A comparison between finasteride, flutamide, and finasteride plus flutamide combination in the treatment of hirsutism.

Journal: Journal of endocrinological investigation 20090101

Title: Low-dose flutamide for women with androgen excess: anti-androgenic efficacy and hepatic safety.

Journal: Journal of endocrinological investigation 20090101

Title: Long-term follow-up after triple treatment of prostate cancer stage pT3.

Journal: Scandinavian journal of urology and nephrology 20090101

Title: The effects of endogenous and exogenous androgens on cardiovascular disease risk factors and progression.

Journal: Reproductive biology and endocrinology : RB&E 20090101

Title: PCOS.

Journal: BMJ clinical evidence 20090101

Title: Obsessive-compulsive disorder and related disorders: a comprehensive survey.

Journal: Annals of general psychiatry 20090101

Title: Uterine and placental expression of TRPV6 gene is regulated via progesterone receptor- or estrogen receptor-mediated pathways during pregnancy in rodents.

Journal: Reproductive biology and endocrinology : RB&E 20090101

Title: Role of maximum androgen blockade in advanced prostate cancer.

Journal: Indian journal of urology : IJU : journal of the Urological Society of India 20090101

Title: Issues in applying multi-arm multi-stage methodology to a clinical trial in prostate cancer: the MRC STAMPEDE trial.

Journal: Trials 20090101

Title: The psychometric validation of a US English satisfaction measure for patients with benign prostatic hyperplasia and lower urinary tract symptoms.

Journal: Health and quality of life outcomes 20090101

Title: Effects of cIAP-1, cIAP-2 and XIAP triple knockdown on prostate cancer cell susceptibility to apoptosis, cell survival and proliferation.

Journal: Molecular cancer 20090101

Title: Long-term effects of environmental endocrine disruptors on reproductive physiology and behavior.

Journal: Frontiers in behavioral neuroscience 20090101

Title: Oocyte-granulosa-theca cell interactions during preantral follicular development.

Journal: Journal of ovarian research 20090101

Title: Molecular fingerprinting of radiation resistant tumors: can we apprehend and rehabilitate the suspects?

Journal: BMC cancer 20090101

Title: Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations.

Journal: Journal of translational medicine 20090101

Title: Small-cell prostate carcinoma: A retrospective analysis of five newly reported cases.

Journal: Indian journal of urology : IJU : journal of the Urological Society of India 20090101

Title: Gene expression meta-analysis supports existence of molecular apocrine breast cancer with a role for androgen receptor and implies interactions with ErbB family.

Journal: BMC medical genomics 20090101

Title: Synthetic and natural compounds that interact with human cytochrome P450 1A2 and implications in drug development.

Journal: Current medicinal chemistry 20090101

Title: Di-(2 ethylhexyl) phthalate and flutamide alter gene expression in the testis of immature male rats.

Journal: Reproductive biology and endocrinology : RB&E 20090101

Title: [Enhancing effect of androgen receptor antagonist on gonadotropic inductors of ovulation in rats with polycystic ovaries].

Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20090101

Title: Benefit of whole pelvic radiotherapy combined with neoadjuvant androgen deprivation for the high-risk prostate cancer.

Journal: Journal of biomedicine & biotechnology 20090101

Title: Androgens and the breast.

Journal: Breast cancer research : BCR 20090101

Title: Experience with the once-yearly histrelin (GnRHa) subcutaneous implant in the treatment of central precocious puberty.

Journal: Drug design, development and therapy 20090101

Title: Functional membrane androgen receptors in colon tumors trigger pro-apoptotic responses in vitro and reduce drastically tumor incidence in vivo.

Journal: Molecular cancer 20090101

Title: Molecular and biochemical effects of a kola nut extract on androgen receptor-mediated pathways.

Journal: Journal of toxicology 20090101

Title: Androgen deprivation therapy for prostate cancer: indications, contraindications and possible consequences.

Journal: F1000 medicine reports 20090101

Title: Defining the molecular action of HDAC inhibitors and synergism with androgen deprivation in ERG-positive prostate cancer.

Journal: International journal of cancer 20081215

Title: Pharmacologic profiling of human and rat cytochrome P450 1A1 and 1A2 induction and competition.

Journal: Archives of toxicology 20081201

Title: Effects of androgens on serum concentrations of gonadotropins and ovarian steroids in gilts.

Journal: Biology of reproduction 20081201

Title: [Low-dose flutamide in the treatment of hyperandrogenism in adolescents].

Journal: Minerva pediatrica 20081201

Title: Comparison of in vitro bioactivation of flutamide and its cyano analogue: evidence for reductive activation by human NADPH:cytochrome P450 reductase.

Journal: Chemical research in toxicology 20081201

Title: Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

Journal: Journal of medicinal chemistry 20081113

Title: Regulation of mRNAs encoding MMP-9 and MMP-2, and their inhibitors TIMP-1 and TIMP-2 by androgens in the rat ventral prostate.

Journal: Molecular and cellular endocrinology 20081106

Title: Watchful waiting beats androgen deprivation therapy in early prostate cancer.

Journal: Journal of the National Cancer Institute 20081105

Title: Nandrolone abuse decreases anxiety and impairs memory in rats via central androgenic receptors.

Journal: The international journal of neuropsychopharmacology 20081101

Title: Androgen regulation of corticotropin-releasing hormone receptor 2 (CRHR2) mRNA expression and receptor binding in the rat brain.

Journal: Experimental neurology 20081101

Title: The oxidation handicap hypothesis and the carotenoid allocation trade-off.

Journal: Journal of evolutionary biology 20081101

Title: Androgens with activity at estrogen receptor beta have anxiolytic and cognitive-enhancing effects in male rats and mice.

Journal: Hormones and behavior 20081101

Title: Hormonal regulation and characterisation of the aldehyde oxidase-like gene of hamster Harderian gland.

Journal: The Journal of steroid biochemistry and molecular biology 20081101

Title: A new allergen in the pharmaceutical industry.

Journal: Contact dermatitis 20081101

Title: Meeting report: moving upstream-evaluating adverse upstream end points for improved risk assessment and decision-making.

Journal: Environmental health perspectives 20081101

Title: Experimental benefits of sex hormones on vascular function and the outcome of hormone therapy in cardiovascular disease.

Journal: Current cardiology reviews 20081101

Title: Docetaxel chemotherapy of Korean patients with hormone- refractory prostate cancer:comparative analysis between 1st-line and 2nd-line docetaxel.

Journal: Yonsei medical journal 20081031

Title: Prognostic significance of disseminated tumor cells in the bone marrow of prostate cancer patients treated with neoadjuvant hormone treatment.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081020

Title: The model anti-androgen flutamide suppresses the expression of typical male stickleback reproductive behaviour.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20081020

Title: Mechanisms involved in testosterone-induced vasodilatation in pig prostatic small arteries.

Journal: Life sciences 20081010

Title: Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.

Journal: Journal of medicinal chemistry 20081009

Title: A new role for tamoxifen in oestrogen receptor-negative breast cancer when it is combined with epigallocatechin gallate.

Journal: British journal of cancer 20081007

Title: Cardiovascular mortality and duration of androgen deprivation for locally advanced prostate cancer: analysis of RTOG 92-02.

Journal: European urology 20081001

Title: Editorial comment on: Cardiovascular mortality and duration of androgen deprivation for locally advanced prostate cancer: analysis of RTOG 92-02.

Journal: European urology 20081001

Title: Effect of heat stress on expression of junction-associated molecules and upstream factors androgen receptor and Wilms' tumor 1 in monkey sertoli cells.

Journal: Endocrinology 20081001

Title: PSA kinetics provide improved prediction of survival in metastatic hormone-refractory prostate cancer.

Journal: Urology 20081001

Title: Potential role of G-protein-coupled receptor 30 (GPR30) in estradiol-17beta-stimulated IGF-I mRNA expression in bovine satellite cell cultures.

Journal: Domestic animal endocrinology 20081001

Title: Comparative anti-androgenic actions of vinclozolin and flutamide on transgenerational adult onset disease and spermatogenesis.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20081001

Title: Methotrexate-induced cutaneous ulceration in patients with erythrodermic mycosis fungoides.

Journal: Therapeutics and clinical risk management 20081001

Title: Androgen regulation of multidrug resistance-associated protein 4 (MRP4/ABCC4) in prostate cancer.

Journal: The Prostate 20080915

Title: Sex differences in expression and differential regulation by androgen and estrogen of two odorant-binding tear lipocalins in lacrimal glands of immature hamsters.

Journal: General and comparative endocrinology 20080915

Title: 5Alpha-dihydrotestosterone up-regulates transthyretin levels in mice and rat choroid plexus via an androgen receptor independent pathway.

Journal: Brain research 20080910

Title: Sex hormone influence on hepatitis in young male A/JCr mice infected with Helicobacter hepaticus.

Journal: Infection and immunity 20080901

Title: Alternative nonsteroidal antiandrogen therapy for advanced prostate cancer that relapsed after initial maximum androgen blockade.

Journal: The Journal of urology 20080901

Title: Effect of testosterone on morphine withdrawal syndrome in rats.

Journal: Asian journal of andrology 20080901

Title: Application and interpretation of hPXR screening data: Validation of reporter signal requirements for prediction of clinically relevant CYP3A4 inducers.

Journal: Biochemical pharmacology 20080901

Title: Sex-specific pathways in early cardiac response to pressure overload in mice.

Journal: Journal of molecular medicine (Berlin, Germany) 20080901

Title: Design and synthesis of carborane-containing androgen receptor (AR) antagonist bearing a pyridine ring.

Journal: Bioorganic & medicinal chemistry 20080901

Title: Computationally identified novel diphenyl- and phenylpyridine androgen receptor antagonist structures.

Journal: Journal of chemical information and modeling 20080901

Title: Effect of deprivation of endogenous follicle stimulating hormone on rat epididymis: a histological evaluation.

Journal: Reproductive biomedicine online 20080901

Title: Hormonal therapy for acne.

Journal: Seminars in cutaneous medicine and surgery 20080901

Title: Modulation by testosterone of an endogenous hERG potassium channel current.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080901

Title: Continuous versus six months a year maximal androgen blockade in the management of prostate cancer: a randomised study.

Journal: European urology 20080801

Title: Editorial comment on: continuous versus six months a year maximal androgen blockade in the management of prostate cancer: a randomised study.

Journal: European urology 20080801

Title: Sexual differentiation of the external genitalia and the timing of puberty in the presence of an antiandrogen in sheep.

Journal: Endocrinology 20080801

Title: Flutamide protects against trauma-hemorrhage-induced liver injury via attenuation of the inflammatory response, oxidative stress, and apopotosis.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20080801

Title: Androgen receptor: a new player associated with apoptosis and proliferation of pancreatic beta-cell in type 1 diabetes mellitus.

Journal: Apoptosis : an international journal on programmed cell death 20080801

Title: [Effects of physiological testosterone on transcription factor activity in human umbilical vein endothelial cells].

Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20080801

Title: Effects of estradiol on the stimulation of dopamine turnover in mesolimbic and nigrostriatal systems by cocaine- and amphetamine-regulated transcript peptide in female rats.

Journal: Neuroscience 20080717

Title: Nandrolone decreases mu opioid receptor expression in SH-SY5Y human neuroblastoma cells.

Journal: Neuroreport 20080716

Title: 4-(Anilino)pyrrole-2-carboxamides: Novel non-steroidal/non-anilide type androgen antagonists effective upon human prostate tumor LNCaP cells with mutated nuclear androgen receptor.

Journal: Bioorganic & medicinal chemistry 20080715

Title: Effect of dihydrotestosterone on hydrogen peroxide-induced apoptosis of mouse embryonic stem cells.

Journal: Journal of cellular physiology 20080701

Title: A new prostate cancer therapeutic approach: combination of androgen ablation with COX-2 inhibitor.

Journal: International journal of cancer 20080701

Title: Roles of IGF-I and the estrogen, androgen and IGF-I receptors in estradiol-17beta- and trenbolone acetate-stimulated proliferation of cultured bovine satellite cells.

Journal: Domestic animal endocrinology 20080701

Title: Bioactivation of flutamide metabolites by human liver microsomes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080701

Title: Regulation of atherosclerotic plaque growth and stability by testosterone and its receptor via influence of inflammatory reaction.

Journal: Vascular pharmacology 20080701

Title: Sex dimorphism in antitumor response of chemotherapeutic drug cisplatin in a murine host-bearing a T-cell lymphoma.

Journal: Anti-cancer drugs 20080701

Title: Risk of prostate cancer recurrence in men treated with radiation alone or in conjunction with combined or less than combined androgen suppression therapy.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080620

Title: Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

Journal: Journal of medicinal chemistry 20080612

Title: BCRP/ABCG2 in the placenta: expression, function and regulation.

Journal: Pharmaceutical research 20080601

Title: Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes.

Journal: The Prostate 20080601

Title: Androgens regulate neprilysin expression: role in reducing beta-amyloid levels.

Journal: Journal of neurochemistry 20080601

Title: Antiandrogen withdrawal in castrate-refractory prostate cancer: a Southwest Oncology Group trial (SWOG 9426).

Journal: Cancer 20080601

Title: Cell lineage analysis demonstrates an endodermal origin of the distal urethra and perineum.

Journal: Developmental biology 20080601

Title: A functionally significant cross-talk between androgen receptor and ErbB2 pathways in estrogen receptor negative breast cancer.

Journal: Neoplasia (New York, N.Y.) 20080601

Title: Changes in gene expression following androgen receptor blockade is not equivalent to androgen ablation by castration in the rat ventral prostate.

Journal: Journal of biosciences 20080601

Title: Ten-year follow-up of radiation therapy oncology group protocol 92-02: a phase III trial of the duration of elective androgen deprivation in locally advanced prostate cancer.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080520

Title: Altered striatal vulnerability to 3-nitropropionic acid in rats due to sex hormone levels during late phase of brain development.

Journal: Neuroscience letters 20080516

Title: A systematic review of commonly used medical treatments for hirsutism in women.

Journal: Clinical endocrinology 20080501

Title: Anabolic androgens restore mating after sexual satiety in male rats.

Journal: Pharmacology, biochemistry, and behavior 20080501

Title: Androgen-regulated cervical ripening: a structural, biomechanical, and molecular analysis.

Journal: American journal of obstetrics and gynecology 20080501

Title: p53 protein expression status and recurrence in men treated with radiation and androgen suppression therapy for higher-risk prostate cancer: a prospective phase II Cancer and Leukemia Group B Study (CALGB 9682).

Journal: Urology 20080501

Title: A multifunctional androgen receptor screening assay using the high-throughput Hypercyt flow cytometry system.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20080501

Title: Androgen regulates neuritin mRNA levels in an in vivo model of steroid-enhanced peripheral nerve regeneration.

Journal: Journal of neurotrauma 20080501

Title: Endocrine gland-derived vascular endothelial growth factor in rat pancreas: genetic expression and testosterone regulation.

Journal: The Journal of endocrinology 20080501

Title: C2C12 myoblastoma cell differentiation and proliferation is stimulated by androgens and associated with a modulation of myostatin and Pax7 expression.

Journal: Journal of molecular endocrinology 20080501

Title: Selected endocrine disrupting compounds (vinclozolin, flutamide, ketoconazole and dicofol): effects on survival, occurrence of males, growth, molting and reproduction of Daphnia magna.

Journal: Environmental science and pollution research international 20080501

Title: Follicle-stimulating hormone affects spermatogonial survival by regulating the intrinsic apoptotic pathway in adult rats.

Journal: Biology of reproduction 20080401

Title: Clinical review: Antiandrogens for the treatment of hirsutism: a systematic review and metaanalyses of randomized controlled trials.

Journal: The Journal of clinical endocrinology and metabolism 20080401

Title: Clinical review: Insulin sensitizers for the treatment of hirsutism: a systematic review and metaanalyses of randomized controlled trials.

Journal: The Journal of clinical endocrinology and metabolism 20080401

Title: Testosterone environment of splenocytes modifies the steroidogenesis of polycystic ovary in rats.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20080401

Title: Androgens predispose males to GABAA-mediated excitotoxicity in the developing hippocampus.

Journal: Experimental neurology 20080401

Title: Combined exposure to anti-androgens causes markedly increased frequencies of hypospadias in the rat.

Journal: International journal of andrology 20080401

Title: Identification in rats of a programming window for reproductive tract masculinization, disruption of which leads to hypospadias and cryptorchidism.

Journal: The Journal of clinical investigation 20080401

Title: Comparison of the clinical efficacy of flutamide and spironolactone plus ethinyloestradiol/cyproterone acetate in the treatment of hirsutism: a randomised controlled study.

Journal: Advances in therapy 20080401

Title: Maximal androgen blockade for advanced prostate cancer.

Journal: Best practice & research. Clinical endocrinology & metabolism 20080401

Title: Levonorgestrel antagonism on estrogen-induced pituitary tumors is mediated by progesterone receptors.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20080401

Title: Use of ethinylestradiol/drospirenone combination in patients with the polycystic ovary syndrome.

Journal: Therapeutics and clinical risk management 20080401

Title: Leuprorelin depot injection: patient considerations in the management of prostatic cancer.

Journal: Therapeutics and clinical risk management 20080401

Title: A review of hormonal therapy for female pattern (androgenic) alopecia.

Journal: Dermatology online journal 20080315

Title: Androgen manipulation alters oxidative DNA adduct levels in androgen-sensitive prostate cancer cells grown in vitro and in vivo.

Journal: Cancer letters 20080308

Title: Alteration in [11C]vorozole binding to aromatase in neuronal cells of rat brain induced by anabolic androgenic steroids and flutamide.

Journal: Neuroreport 20080305

Title: Orchiectomy or testosterone receptor blockade reduces intestinal mucosal damage caused by ischemia-reperfusion insult.

Journal: Pediatric surgery international 20080301

Title: Endocrine disrupting chemicals (EDC) with (anti)estrogenic and (anti)androgenic modes of action affecting reproductive biology of Xenopus laevis: II. Effects on gonad histomorphology.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20080301

Title: Quantitative evaluation of sebum lipid components with nuclear magnetic resonance.

Journal: Journal of lipid research 20080301

Title: Early orchiopexy improves subsequent testicular development and spermatogenesis in the experimental cryptorchid rat model.

Journal: The Journal of urology 20080301

Title: Evidence for the participation of calcium in non-genomic relaxations induced by androgenic steroids in rat vas deferens.

Journal: British journal of pharmacology 20080301

Title: Dihydrotestosterone influenced numbers of healthy follicles and follicular amounts of LH receptor mRNA during the follicular phase of the estrous cycle in gilts.

Journal: Reproduction (Cambridge, England) 20080301

Title: Blockade of androgen receptors is sufficient to alter the sexual differentiation of the substantia nigra pars reticulata seizure-controlling network.

Journal: Epileptic disorders : international epilepsy journal with videotape 20080301

Title: Parenteral oestrogen in the treatment of prostate cancer: a systematic review.

Journal: British journal of cancer 20080226

Title: Flutamide reduced prostate cancer development and prostate stem cell antigen mRNA expression in high grade prostatic intraepithelial neoplasia.

Journal: International journal of cancer 20080215

Title: Heteronuclear 19F-1H statistical total correlation spectroscopy as a tool in drug metabolism: study of flucloxacillin biotransformation.

Journal: Analytical chemistry 20080215

Title: CYP1B1 expression is induced by docetaxel: effect on cell viability and drug resistance.

Journal: British journal of cancer 20080212

Title: Androgens stimulate endothelial progenitor cells through an androgen receptor-mediated pathway.

Journal: Clinical endocrinology 20080201

Title: Hormonal regulation of BCRP expression in human placental BeWo cells.

Journal: Pharmaceutical research 20080201

Title: Long-term treatment sequelae after external beam irradiation with or without hormonal manipulation for adenocarcinoma of the prostate: analysis of radiation therapy oncology group studies 85-31, 86-10, and 92-02.

Journal: International journal of radiation oncology, biology, physics 20080201

Title: Gonadal steroid hormones maintain the stress-induced acetylcholine release in the hippocampus: simultaneous measurements of the extracellular acetylcholine and serum corticosterone levels in the same subjects.

Journal: Endocrinology 20080201

Title: Pioglitazone (7.5 mg/day) added to flutamide-metformin in women with androgen excess: additional increments of visfatin and high molecular weight adiponectin.

Journal: Clinical endocrinology 20080201

Title: Short-term neoadjuvant androgen deprivation therapy and external-beam radiotherapy for locally advanced prostate cancer: long-term results of RTOG 8610.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080201

Title: Review of the histological effects of the anti-androgen, flutamide, on mouse testis.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20080201

Title: Impact of sex and hormones on new cells in the developing rat hippocampus: a novel source of sex dimorphism?

Journal: The European journal of neuroscience 20080201

Title: Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.

Journal: JAMA 20080123

Title: Androgen resistance in prostate cancer.

Journal: British journal of cancer 20080115

Title: Eliciting patient preferences for hormonal therapy options in the treatment of metastatic prostate cancer.

Journal: Prostate cancer and prostatic diseases 20080101

Title: In vivo and in vitro effects of flutamide and diethylstilbestrol on fetal testicular steroidogenesis in the rat.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20080101

Title: Evidence that androgens regulate early developmental events, prior to sexual differentiation.

Journal: Endocrinology 20080101

Title: Potassium channels are involved in testosterone-induced vasorelaxation of human umbilical artery.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20080101

Title: The methoxychlor metabolite, HPTE, directly inhibits the catalytic activity of cholesterol side-chain cleavage (P450scc) in cultured rat ovarian cells.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20080101

Title: Clinical results of isolated tibial component revisions with femoral component retention.

Journal: The Journal of arthroplasty 20080101

Title: Alterations of Sertoli cell activity in the long-term testicular germ cell death process induced by fetal androgen disruption.

Journal: The Journal of endocrinology 20080101

Title: Can prophylactic breast irradiation contribute to cardiac toxicity in patients with prostate cancer receiving androgen suppressing drugs?

Journal: Radiation oncology (London, England) 20080101

Title: 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (p,p'-DDE) disrupts the estrogen-androgen balance regulating the growth of hormone-dependent breast cancer cells.

Journal: Breast cancer research : BCR 20080101

Title: Peroxisome proliferator-activated receptors as mediators of phthalate-induced effects in the male and female reproductive tract: epidemiological and experimental evidence.

Journal: PPAR research 20080101

Title: Testosterone influences renal electrolyte excretion in SHR/y and WKY males.

Journal: BMC physiology 20080101

Title: Systematic review of the clinical effect of glucocorticoids on nonhematologic malignancy.

Journal: BMC cancer 20080101

Title: Parenteral estrogen versus combined androgen deprivation in the treatment of metastatic prostatic cancer: part 2. Final evaluation of the Scandinavian Prostatic Cancer Group (SPCG) Study No. 5.

Journal: Scandinavian journal of urology and nephrology 20080101

Title: Antiproliferative and cytostatic effects of the natural product eupatorin on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism.

Journal: Breast cancer research : BCR 20080101

Title: Characterization of androgen regulation of ZEB-1 and PSA in 22RV1 prostate cancer cells.

Journal: Advances in experimental medicine and biology 20080101

Title: The relationship between the biochemical control outcomes and the quality of planning of high-dose rate brachytherapy as a boost to external beam radiotherapy for locally and locally advanced prostate cancer using the RTOG-ASTRO Phoenix definition.

Journal: International journal of medical sciences 20080101

Title: Bench-to-bedside review: latest results in hemorrhagic shock.

Journal: Critical care (London, England) 20080101

Title: Evaluation of resistance index in patients with prostate cancer.

Journal: Anticancer research 20080101

Title: Recent advances in the investigation of curcuminoids.

Journal: Chinese medicine 20080101

Title: A dramatic, objective antiandrogen withdrawal response: case report and review of the literature.

Journal: Journal of hematology & oncology 20080101

Title: Membrane androgen receptor activation triggers down-regulation of PI-3K/Akt/NF-kappaB activity and induces apoptotic responses via Bad, FasL and caspase-3 in DU145 prostate cancer cells.

Journal: Molecular cancer 20080101

Title: Selective androgen receptor modulators in preclinical and clinical development.

Journal: Nuclear receptor signaling 20080101

Title: Strategies for prostate cancer prevention: Review of the literature.

Journal: Indian journal of urology : IJU : journal of the Urological Society of India 20080101

Title: Quality of life measurement in bone metastases: A literature review.

Journal: Journal of pain research 20080101

Title: The effect of sodium valproate on the biochemical parameters of reproductive function in male albino Wistar rats.

Journal: Indian journal of pharmacology 20080101

Title: Aspirin and hormone therapy for prostate cancer.

Journal: The New England journal of medicine 20071227

Title: The anatomy of the cremaster muscle during inguinoscrotal testicular descent in the rat.

Journal: Journal of pediatric surgery 20071201

Title: Combined exposure to anti-androgens exacerbates disruption of sexual differentiation in the rat.

Journal: Environmental health perspectives 20071201

Title: The efficacy of neoadjuvant androgen deprivation therapy as a prostate volume reduction before brachytherapy for clinically localized prostate cancer.

Journal: Acta medica Okayama 20071201

Title: Antiandrogen pretreatment alters cocaine pharmacokinetics in men.

Journal: Journal of addiction medicine 20071201

Title: Weekly administration of docetaxel in combination with estramustine and celecoxib in patients with advanced hormone-refractory prostate cancer: final results from a phase II study.

Journal: British journal of cancer 20071105

Title: Testosterone directly induces progesterone production and interacts with physiological concentrations of LH to increase granulosa cell progesterone production in laying hens (Gallus domesticus).

Journal: Animal reproduction science 20071101

Title: Targeted transfollicular delivery of artocarpin extract from Artocarpus incisus by means of microparticles.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20071101

Title: Dystroglycan expression is reduced during prostate tumorigenesis and is regulated by androgens in prostate cancer cells.

Journal: Journal of cellular physiology 20071101

Title: Evaluation of the antiandrogenic effects of flutamide, DDE, and linuron in the weanling rat assay using organ weight, histopathological, and proteomic approaches.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20071101

Title: Inhibition of oxidative-stress-induced platelet aggregation by androgen at physiological levels via its receptor is associated with the reduction of thromboxane A2 release from platelets.

Journal: Steroids 20071101

Title: A new highly specific and robust yeast androgen bioassay for the detection of agonists and antagonists.

Journal: Analytical and bioanalytical chemistry 20071101

Title: Association of body mass index with response and survival in men with metastatic prostate cancer: Southwest Oncology Group trials 8894 and 9916.

Journal: The Journal of urology 20071101

Title: Novel flutamide regulated genes in the rat ventral prostate: differential modulation of their expression by castration and flutamide treatments.

Journal: Asian journal of andrology 20071101

Title: Flutamide metformin for post-menarcheal girls with preclinical ovarian androgen excess: evidence for differential response by androgen receptor genotype.

Journal: European journal of endocrinology 20071101

Title: Activation of the androgen receptor alters the intracellular calcium response to glutamate in primary hippocampal neurons and modulates sarco/endoplasmic reticulum calcium ATPase 2 transcription.

Journal: Neuroscience 20071012

Title: Expression pattern of sulfated glycoprotein-2 (SGP-2) mRNA in rat testes exposed to endocrine disruptors.

Journal: The Journal of reproduction and development 20071001

Title: Androgen receptor blockade in experimental combination therapy of pancreatic cancer.

Journal: The Journal of surgical research 20071001

Title: PRMT2, a member of the protein arginine methyltransferase family, is a coactivator of the androgen receptor.

Journal: The Journal of steroid biochemistry and molecular biology 20071001

Title: The change in the dihydrotestosterone level in the prostate before and after androgen deprivation therapy in connection with prostate cancer aggressiveness using the Gleason score.

Journal: The Journal of urology 20071001

Title: Suspected cross-hepatotoxicity of flutamide and cyproterone acetate.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20071001

Title: Transport, metabolism, and hepatotoxicity of flutamide, drug-drug interaction with acetaminophen involving phase I and phase II metabolites.

Journal: Chemical research in toxicology 20071001

Title: Pharmacological causes of hyperprolactinemia.

Journal: Therapeutics and clinical risk management 20071001

Title: Evaluation of the rodent Hershberger bioassay: testing of coded chemicals and supplementary molecular-biological and biochemical investigations.

Journal: Toxicology 20070924

Title: Racial differences in CYP3A4 genotype and survival among men treated on Radiation Therapy Oncology Group (RTOG) 9202: a phase III randomized trial.

Journal: International journal of radiation oncology, biology, physics 20070901

Title: Are steroids obligatory mediators of luteinizing hormone/human chorionic gonadotropin-triggered resumption of meiosis in mammals?

Journal: Endocrinology 20070901

Title: Long-term efficacy and tolerability of flutamide combined with oral contraception in moderate to severe hirsutism: a 12-month, double-blind, parallel clinical trial.

Journal: The Journal of clinical endocrinology and metabolism 20070901

Title: Persisting benefits 12-18 months after discontinuation of pubertal metformin therapy in low birthweight girls.

Journal: Clinical endocrinology 20070901

Title: Effects of endocrine disrupting chemicals on expression of phospholipid hydroperoxide glutathione peroxidase mRNA in rat testes.

Journal: Journal of veterinary science 20070901

Title: Comparison of the cytotoxicity of the nitroaromatic drug flutamide to its cyano analogue in the hepatocyte cell line TAMH: evidence for complex I inhibition and mitochondrial dysfunction using toxicogenomic screening.

Journal: Chemical research in toxicology 20070901

Title: Neuroendocrine effects of androgens in adult polycystic ovary syndrome and female puberty.

Journal: Seminars in reproductive medicine 20070901

Title: Does small-cell phenotype predict the natural history of prostate cancer? A case study in disease behavior.

Journal: Nature clinical practice. Oncology 20070901

Title: The modulatory role of androgens and progestins in the induction of vasorelaxation in human umbilical artery.

Journal: Life sciences 20070901

Title: Fatal spontaneous tumor lysis syndrome in a patient with metastatic, androgen-independent prostate cancer.

Journal: Southern medical journal 20070901

Title: Prostate-cancer-specific survival and clinical progression-free survival in men with prostate cancer treated intermittently with testosterone-inactivating pharmaceuticals.

Journal: Urology 20070901

Title: [Effects of testosterone on extracellular signal-regulated kinase 1/2 phosphorylation in human umbilical vein endothelial cells].

Journal: Zhonghua nan ke xue = National journal of andrology 20070901

Title: Combined androgen blockade in advanced prostate cancer: looking back to move forward.

Journal: Clinical genitourinary cancer 20070901

Title: Efficacy of the combination of long-acting release octreotide and tamoxifen in patients with advanced hepatocellular carcinoma: a randomised multicentre phase III study.

Journal: British journal of cancer 20070828

Title: Nanomolar concentrations of anabolic-androgenic steroids amplify excitotoxic neuronal death in mixed mouse cortical cultures.

Journal: Brain research 20070824

Title: Androgen activates PEG10 to promote carcinogenesis in hepatic cancer cells.

Journal: Oncogene 20070823

Title: Design, synthesis, and in vivo SAR of a novel series of pyrazolines as potent selective androgen receptor modulators.

Journal: Journal of medicinal chemistry 20070809

Title: The use of metabolomics for the discovery of new biomarkers of effect.

Journal: Toxicology letters 20070730

Title: The effects of atamestane and toremifene alone and in combination compared with letrozole on bone, serum lipids and the uterus in an ovariectomized rat model.

Journal: Breast cancer research and treatment 20070701

Title: Receptor-mediated suppression of cardiac heat-shock protein 72 expression by testosterone in male rat heart.

Journal: Endocrinology 20070701

Title: Identification of a novel glutathione conjugate of flutamide in incubations with human liver microsomes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070701

Title: Dysgenesis and histological changes of genitals and perturbations of gene expression in male rats after in utero exposure to antiandrogen mixtures.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070701

Title: The critical time window for androgen-dependent development of the Wolffian duct in the rat.

Journal: Endocrinology 20070701

Title: A novel synthetic compound that interrupts androgen receptor signaling in human prostate cancer cells.

Journal: Molecular cancer therapeutics 20070701

Title: Differential expression of 3beta-hydroxysteroid dehydrogenase mRNA in rat testes exposed to endocrine disruptors.

Journal: The Journal of reproduction and development 20070601

Title: Gender dimorphism in the myeloid differentiation of bone marrow precursor cells in a murine host bearing a T cell lymphoma.

Journal: Journal of reproductive immunology 20070601

Title: Induction of cyp1a1 is a nonspecific biomarker of aryl hydrocarbon receptor activation: results of large scale screening of pharmaceuticals and toxicants in vivo and in vitro.

Journal: Molecular pharmacology 20070601

Title: Flutamide and cyproterone acetate exert agonist effects: induction of androgen receptor-dependent neuroprotection.

Journal: Endocrinology 20070601

Title: Effects of steroidal and non-steroidal antiandrogens on wild-type and mutant androgen receptors.

Journal: The Prostate 20070601

Title: Dihydrotestosterone inhibits tumor necrosis factor alpha induced interleukin-1alpha mRNA expression in rheumatoid fibroblast-like synovial cells.

Journal: Biological & pharmaceutical bulletin 20070601

Title: Reciprocal regulation of 5alpha-dihydrotestosterone, interleukin-6 and interleukin-8 during proliferation of epithelial ovarian carcinoma.

Journal: Cancer biology & therapy 20070601

Title: Claudin-11 expression and localisation is regulated by androgens in rat Sertoli cells in vitro.

Journal: Reproduction (Cambridge, England) 20070601

Title: Testosterone inhibits matrix metalloproteinase-1 production in human endometrial stromal cells in vitro.

Journal: Reproduction (Cambridge, England) 20070601

Title: [Mediastinal lymph nodes during the course of a metastatic prostate cancer].

Journal: Actas urologicas espanolas 20070601

Title: Female pattern hair loss: current treatment concepts.

Journal: Clinical interventions in aging 20070601

Title: Androgen disruption of early development in Qurt strain medaka (Oryzias latipes).

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20070515

Title: Effects of long-term flutamide treatment during development in zebra finches.

Journal: Neuroscience letters 20070511

Title: Impact of testosterone on cardiac L-type calcium channels and Ca2+ sparks: acute actions antagonize chronic effects.

Journal: Cell calcium 20070501

Title: Role of androgens in fetal testis development and dysgenesis.

Journal: Endocrinology 20070501

Title: Combined low-dose pioglitazone, flutamide, and metformin for women with androgen excess.

Journal: The Journal of clinical endocrinology and metabolism 20070501

Title: Correlation between protein accumulation profiles and conventional toxicological findings using a model antiandrogenic compound, flutamide.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070501

Title: Non-steroidal antiandrogens act as AF-1 agonists under conditions of high androgen-receptor expression.

Journal: The Prostate 20070501

Title: Vitiliginous lesions after photosensitive dermatitis due to flutamide.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20070501

Title: Sex differences in angiotensin II- induced hypertension.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20070501

Title: The OECD program to validate the rat Hershberger bioassay to screen compounds for in vivo androgen and antiandrogen responses: phase 2 dose-response studies.

Journal: Environmental health perspectives 20070501

Title: Region-specific mechanisms for testosterone-induced Fos in hamster brain.

Journal: Brain research 20070413

Title: Automated determination of flutamide by a validated flow-injection method: application to dissolution studies of pharmaceutical tablets.

Journal: Journal of pharmaceutical and biomedical analysis 20070411

Title: Effect of selected fluorinated drugs in a 'ringing' gel on rheological behaviour and skin permeation.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20070401

Title: Effects of various pesticides on human 5alpha-reductase activity in prostate and LNCaP cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20070401

Title: Effects of aromatase inhibitors on human osteoblast and osteoblast-like cells: a possible androgenic bone protective effects induced by exemestane.

Journal: Bone 20070401

Title: Search for residual prostate cancer on pT0 radical prostatectomy after positive biopsy.

Journal: Virchows Archiv : an international journal of pathology 20070401

Title: Cognitive performance in rhesus monkeys varies by sex and prenatal androgen exposure.

Journal: Hormones and behavior 20070401

Title: Involvement of bile salt export pump in flutamide-induced cholestatic hepatitis.

Journal: Biological & pharmaceutical bulletin 20070401

Title: Dehydroepiandrosterone improves murine osteoblast growth and bone tissue morphometry via mitogen-activated protein kinase signaling pathway independent of either androgen receptor or estrogen receptor.

Journal: Journal of molecular endocrinology 20070401

Title: Physiological testosterone stimulates tissue plasminogen activator and tissue factor pathway inhibitor and inhibits plasminogen activator inhibitor type 1 release in endothelial cells.

Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20070401

Title: Sex-specific effects of androgen and estrogen on proliferation of the embryonic chicken hypothalamic neurons.

Journal: Endocrine 20070401

Title: Testosterone and oxidative stress: the oxidation handicap hypothesis.

Journal: Proceedings. Biological sciences 20070322

Title: Cellular and extracellular behavior in the gerbil (Meriones unguiculatus) ventral prostate following different types of castration and the consequences of testosterone replacement.

Journal: Cell biology international 20070301

Title: Ligand-specific dynamics of the androgen receptor at its response element in living cells.

Journal: Molecular and cellular biology 20070301

Title: Estrogen receptor (ER) agonists and androgen receptor (AR) antagonists in effluents from Norwegian North Sea oil production platforms.

Journal: Marine pollution bulletin 20070301

Title: The effect of brachytherapy, external beam irradiation and hormonal therapy on prostate volume.

Journal: The Journal of urology 20070301

Title: Curcumin downregulates homeobox gene NKX3.1 in prostate cancer cell LNCaP.

Journal: Acta pharmacologica Sinica 20070301

Title: The effect of testosterone, dihydrotestosterone and oestradiol on the re-initiation of spermatogenesis in the adult photoinhibited Djungarian hamster.

Journal: The Journal of endocrinology 20070301

Title: Chronic testosterone treatment induces selective insulin resistance in subcutaneous adipocytes of women.

Journal: The Journal of endocrinology 20070301

Title: Long-term effectiveness of luteinizing hormone-releasing hormone agonist or antiandrogen monotherapy in elderly men with localized prostate cancer (T1-2): a retrospective study.

Journal: Asian journal of andrology 20070301

Title: A novel amphibian tier 2 testing protocol: a 30-week exposure of Xenopus tropicalis to the antiandrogen flutamide.

Journal: Environmental toxicology and chemistry 20070301

Title: Effects of flutamide as a second-line agent for maximum androgen blockade of hormone refractory prostate cancer.

Journal: International journal of urology : official journal of the Japanese Urological Association 20070301

Title: Gene expression profiles revealing the mechanisms of anti-androgen- and estrogen-induced feminization in fish.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20070227

Title: Hypothalamus region-specific global gene expression profiling in early stages of central endocrine disruption in rat neonates injected with estradiol benzoate or flutamide.

Journal: Developmental neurobiology 20070215

Title: Androgens' performance-enhancing effects in the inhibitory avoidance and water maze tasks may involve actions at intracellular androgen receptors in the dorsal hippocampus.

Journal: Neurobiology of learning and memory 20070201

Title: Estrogen-induced upregulation of AR expression and enhancement of AR nuclear translocation in mouse fallopian tubes in vivo.

Journal: American journal of physiology. Endocrinology and metabolism 20070201

Title: Estrogen signaling and disruption of androgen metabolism in acquired androgen-independence during cadmium carcinogenesis in human prostate epithelial cells.

Journal: The Prostate 20070201

Title: Expression of galectin-3 and its regulation in the testes.

Journal: International journal of andrology 20070201

Title: Quantitative determination of lobe specificity of mRNA expression of androgen-dependent genes in the rat prostate gland.

Journal: Endocrine journal 20070201

Title: Flutamide attenuates pro-inflammatory cytokine production and hepatic injury following trauma-hemorrhage via estrogen receptor-related pathway.

Journal: Annals of surgery 20070201

Title: [Development of novel nuclear receptor ligands based on receptor-folding inhibition hypothesis].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20070201

Title: Clinical efficacy of alternative antiandrogen therapy in Japanese men with relapsed prostate cancer after first-line hormonal therapy.

Journal: International journal of urology : official journal of the Japanese Urological Association 20070201

Title: Mechanisms of acquired androgen independence during arsenic-induced malignant transformation of human prostate epithelial cells.

Journal: Environmental health perspectives 20070201

Title: Hormone ablation therapy: lightening the load for today's prostate cancer patient.

Journal: Urologic nursing 20070201

Title: The androgen receptor T877A mutant recruits LXXLL and FXXLF peptides differently than wild-type androgen receptor in a time-resolved fluorescence resonance energy transfer assay.

Journal: Biochemistry 20070123

Title: Antiandrogenic activity of pyrethroid pesticides and their metabolite in reporter gene assay.

Journal: Chemosphere 20070101

Title: Surgical and chemical castration induce differential histological response in prostate lobes of Mongolian gerbil.

Journal: Micron (Oxford, England : 1993) 20070101

Title: Androgen and the elaborate courtship behavior of a tropical lekking bird.

Journal: Hormones and behavior 20070101

Title: Histopathological changes induced by therapies in the benign prostate and prostate adenocarcinoma.

Journal: Histology and histopathology 20070101

Title: Endocrine disrupters with (anti)estrogenic and (anti)androgenic modes of action affecting reproductive biology of Xenopus laevis: I. Effects on sex steroid levels and biomarker expression.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20070101

Title: Androgen decreases osteoprotegerin expression in prostate cancer cells.

Journal: Prostate cancer and prostatic diseases 20070101

Title: Phase II study of neoadjuvant androgen deprivation followed by external-beam radiotherapy with 9 months of androgen deprivation for intermediate- to high-risk localized prostate cancer.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070101

Title: Influence for testicular development and histological peculiarity in the testes of flutamide-induced cryptorchid rat model.

Journal: International journal of urology : official journal of the Japanese Urological Association 20070101

Title: Induction of human arylamine N-acetyltransferase type I by androgens in human prostate cancer cells.

Journal: Cancer research 20070101

Title: Early effects of pharmacological androgen deprivation in human prostate cancer.

Journal: BJU international 20070101

Title: Perturbation of spermatogenesis by androgen antagonists directly injected into seminiferous tubules of live mice.

Journal: Reproduction (Cambridge, England) 20070101

Title: Early onset pauciarticular arthritis is the major risk factor for naproxen-induced pseudoporphyria in juvenile idiopathic arthritis.

Journal: Arthritis research & therapy 20070101

Title: Squamous cell carcinoma of the prostate: long-term survival after combined chemo-radiation.

Journal: Radiation oncology (London, England) 20070101

Title: Experimental arterial thrombosis regulated by androgen and its receptor via modulation of platelet activation.

Journal: Thrombosis research 20070101

Title: Suppressive effects of antiandrogens, finasteride and flutamide on development of prostatic lesions in a transgenic rat model.

Journal: Prostate cancer and prostatic diseases 20070101

Title: [Endocrine disruptor compounds and their role in the developmental programming of the reproductive axis].

Journal: Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20070101

Title: Preliminary investigation of changes in the sexually dimorphic nucleus of the rat medial preoptic area following prenatal exposure to fenitrothion.

Journal: Journal of applied toxicology : JAT 20070101

Title: A phase II trial of docetaxel and erlotinib as first-line therapy for elderly patients with androgen-independent prostate cancer.

Journal: BMC cancer 20070101

Title: Can a single model explain both breast cancer and prostate cancer?

Journal: Theoretical biology & medical modelling 20070101

Title: No supra-additive effects of goserelin and radiotherapy on clonogenic survival of prostate carcinoma cells in vitro.

Journal: Radiation oncology (London, England) 20070101

Title: Comparison of three instrumental methods for the objective evaluation of radiotherapy induced erythema in breast cancer patients and a study of the effect of skin lotions.

Journal: Acta oncologica (Stockholm, Sweden) 20070101

Title: Pathogenesis of prostate cancer and hormone refractory prostate cancer.

Journal: Indian journal of urology : IJU : journal of the Urological Society of India 20070101

Title: Treatment algorithm in hormone-resistant prostate cancer: Practical guidelines.

Journal: Indian journal of urology : IJU : journal of the Urological Society of India 20070101

Title: Sex steroids modulate changes in social and sexual preference during juvenile development in zebra finches.

Journal: Hormones and behavior 20061201

Title: Testosterone stimulates the primary to secondary follicle transition in bovine follicles in vitro.

Journal: Biology of reproduction 20061201

Title: Androgens differentially potentiate mouse intestinal smooth muscle by nongenomic activation of polyamine synthesis and Rho kinase activation.

Journal: Endocrinology 20061201

Title: Cancer-specific mortality after radiation therapy with short-course hormonal therapy or radical prostatectomy in men with localized, intermediate-risk to high-risk prostate cancer.

Journal: Cancer 20061201

Title: Role of 5 alpha-reductase inhibitors in the management of prostate cancer.

Journal: Clinical interventions in aging 20061201

Title: [Bone metastasis of prostatic cancer imitating Paget's sarcoma].

Journal: Deutsche medizinische Wochenschrift (1946) 20061110

Title: Anti-progestogenic effect of flutamide on uterine expression of calbindin-D9k mRNA and protein in immature mice.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20061101

Title: Long-term and immediate effect of testosterone on single T-type calcium channel in neonatal rat cardiomyocytes.

Journal: Endocrinology 20061101

Title: Effect of bisphenol A, tetrachlorobisphenol A and pentachlorophenol on the transcriptional activities of androgen receptor-mediated reporter gene.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20061101

Title: The effect of flutamide on systemic and renal hemodynamics in Zucker diabetic rats: paradoxic renal vasodilator response to endothelin-1 and TXA2 receptor activation in female sex.

Journal: Journal of cardiovascular pharmacology 20061101

Title: Effects of 17beta-estradiol and flutamide on splenic macrophages and splenocytes after trauma-hemorrhage.

Journal: Cytokine 20061101

Title: Multiple hormonal activities of UV filters and comparison of in vivo and in vitro estrogenic activity of ethyl-4-aminobenzoate in fish.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20061012

Title: Improving the outcome of patients with castration-resistant prostate cancer through rational drug development.

Journal: British journal of cancer 20061009

Title: Dopamine agonists, anti-progestins, anti-androgens, long-term-release GnRH agonists and anti-estrogens in canine reproduction: a review.

Journal: Theriogenology 20061001

Title: Androgen-dependent mechanisms of Wolffian duct development and their perturbation by flutamide.

Journal: Endocrinology 20061001

Title: Expression profiling of endocrine-disrupting compounds using a customized Cyprinus carpio cDNA microarray.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20061001

Title: Treatment with flutamide, metformin, and their combination added to a hypocaloric diet in overweight-obese women with polycystic ovary syndrome: a randomized, 12-month, placebo-controlled study.

Journal: The Journal of clinical endocrinology and metabolism 20061001

Title: Effects of 17beta-estradiol and flutamide on inflammatory response and distant organ damage following trauma-hemorrhage in metestrus females.

Journal: Journal of leukocyte biology 20061001

Title: Results of radiation therapy combined with neoadjuvant hormonal therapy for stage III prostate cancer: comparison of two different definitions of PSA failure.

Journal: International journal of clinical oncology 20061001

Title: Persistent prostate-specific antigen expression after neoadjuvant androgen depletion: an early predictor of relapse or incomplete androgen suppression.

Journal: Urology 20061001

Title: Bioactivation and hepatotoxicity of nitroaromatic drugs.

Journal: Current drug metabolism 20061001

Title: [Histological investigation of prostate cancer treated with hormonal agents].

Journal: Hinyokika kiyo. Acta urologica Japonica 20061001

Title: The effect of androgen blockade on granulosa cell estradiol production after follicle-stimulating hormone stimulation in women with polycystic ovary syndrome.

Journal: The Journal of clinical endocrinology and metabolism 20060901

Title: [Keyrole of endocrinology in the victory against prostate cancer].

Journal: Bulletin du cancer 20060901

Title: Development of a stickleback kidney cell culture assay for the screening of androgenic and anti-androgenic endocrine disrupters.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20060823

Title: A systematic review of the effectiveness of docetaxel and mitoxantrone for the treatment of metastatic hormone-refractory prostate cancer.

Journal: British journal of cancer 20060821

Title: Identification of a lead pharmacophore for the development of potent nuclear receptor modulators as anticancer and X syndrome disease therapeutic agents.

Journal: Bioorganic & medicinal chemistry letters 20060815

Title: Castration prevents suppression of MHC class II (Ia) expression on macrophages after trauma-hemorrhage.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20060801

Title: Intrahippocampal administration of an androgen receptor antagonist, flutamide, can increase anxiety-like behavior in intact and DHT-replaced male rats.

Journal: Hormones and behavior 20060801

Title: PTOV1: a novel testosterone-induced atherogenic gene in human aorta.

Journal: The Journal of pathology 20060801

Title: Androgen and anti-androgen treatment modulates androgen receptor activity and DJ-1 stability.

Journal: The Prostate 20060801

Title: Sex differences in otoacoustic emissions measured in rhesus monkeys (Macaca mulatta).

Journal: Hormones and behavior 20060801

Title: Antiandrogen treatments in locally advanced prostate cancer: are they all the same?

Journal: Journal of cancer research and clinical oncology 20060801

Title: The OECD program to validate the rat Hershberger bioassay to screen compounds for in vivo androgen and antiandrogen responses. Phase 1: use of a potent agonist and a potent antagonist to test the standardized protocol.

Journal: Environmental health perspectives 20060801

Title: Chiral dimethylamine flutamide derivatives--modeling, synthesis, androgen receptor affinities and carbon-11 labeling.

Journal: Nuclear medicine and biology 20060801

Title: Synthesis and biological evaluation of a nonsteroidal bromine-76-labeled androgen receptor ligand 3-[76Br]bromo-hydroxyflutamide.

Journal: Nuclear medicine and biology 20060801

Title: Possibility of recovery of estrogen sensitivity following high-dose glucocorticoid therapy in a patient with hormone-refractory prostate cancer.

Journal: International journal of clinical oncology 20060801

Title: Impact of neoadjuvant hormonal therapy on dose-volume histograms in patients with localized prostate cancer under radical radiation therapy.

Journal: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20060801

Title: [DHEA inhibits apoptosis of murine OB through MAPK signaling pathways independent of either ARs or ERs].

Journal: Fen zi xi bao sheng wu xue bao = Journal of molecular cell biology 20060801

Title: Anti-estrogen ICI 182.780 and anti-androgen flutamide induce tyrosine phosphorylation of cortactin in the ectoplasmic specialization between the Sertoli cell and spermatids in the mouse testis.

Journal: Biochemical and biophysical research communications 20060721

Title: Androgen and fibroblast growth factor 8 (FGF8) downregulation of thrombospondin 1 (TSP1) in mouse breast cancer cells.

Journal: Molecular and cellular endocrinology 20060711

Title: Flutamide depresses expression of cortactin in the ectoplasmic specialization between the Sertoli cells and spermatids in the mouse testis.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060701

Title: In vitro profiling of the endocrine-disrupting potency of brominated flame retardants.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060701

Title: Profiling the hepatic effects of flutamide in rats: a microarray comparison with classical aryl hydrocarbon receptor ligands and atypical CYP1A inducers.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060701

Title: Anti-androgen flutamide affects gonadal development and reproduction in medaka (Oryzias latipes).

Journal: Marine environmental research 20060701

Title: Prostate androgen-regulated gene: a novel potential target for androgen-independent prostate cancer therapy.

Journal: Asian journal of andrology 20060701

Title: Low-dose flutamide-metformin therapy for hyperinsulinemic hyperandrogenism in nonobese adolescents and women.

Journal: Fertility and sterility 20060701

Title: Use of antiandrogens as therapy for women with polycystic ovary syndrome.

Journal: Fertility and sterility 20060701

Title: Prenatal growth restraint followed by catch-up of weight: a hyperinsulinemic pathway to polycystic ovary syndrome.

Journal: Fertility and sterility 20060701

Title: [The effects of flutamide on the full gene expression of early testis development of embryonic period male SD].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20060701

Title: GREB1 is a novel androgen-regulated gene required for prostate cancer growth.

Journal: The Prostate 20060601

Title: Dimethandrolone undecanoate: a new potent orally active androgen with progestational activity.

Journal: Endocrinology 20060601

Title: Effects of neonatal exposure to 4-tert-octylphenol, diethylstilbestrol, and flutamide on steroidogenesis in infantile rat testis.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060601

Title: Flutamide metabolism in four different species in vitro and identification of flutamide metabolites in human patient urine by high performance liquid chromatography/tandem mass spectrometry.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060601

Title: The role of sex steroids in courtship, pairing and pairing behaviors in the socially monogamous zebra finch.

Journal: Hormones and behavior 20060601

Title: Evaluation of a commercial kit for measuring vitellogenin in the fathead minnow (Pimephales promelas).

Journal: Ecotoxicology and environmental safety 20060601

Title: Testosterone antagonist (flutamide) blocks ovulation and preovulatory surges of progesterone, luteinizing hormone and oestradiol in laying hens.

Journal: Reproduction (Cambridge, England) 20060601

Title: Maximal androgen blockade for the treatment of metastatic prostate cancer--a systematic review.

Journal: Current oncology (Toronto, Ont.) 20060601

Title: Flutamide in unresectable pancreatic adenocarcinoma: a randomized, double-blind, placebo-controlled trial.

Journal: Investigational new drugs 20060501

Title: DHT and testosterone, but not DHEA or E2, differentially modulate IGF-I, IGFBP-2, and IGFBP-3 in human prostatic stromal cells.

Journal: American journal of physiology. Endocrinology and metabolism 20060501

Title: The corepressors silencing mediator of retinoid and thyroid hormone receptor and nuclear receptor corepressor are involved in agonist- and antagonist-regulated transcription by androgen receptor.

Journal: Molecular endocrinology (Baltimore, Md.) 20060501

Title: Androgen effects on hippocampal CA1 spine synapse numbers are retained in Tfm male rats with defective androgen receptors.

Journal: Endocrinology 20060501

Title: Detection of a new N-oxidized metabolite of flutamide, N-[4-nitro-3-(trifluoromethyl)phenyl]hydroxylamine, in human liver microsomes and urine of prostate cancer patients.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Adverse effects to quality of life arising from treatment can recover with intermittent androgen suppression in men with prostate cancer.

Journal: European journal of cancer (Oxford, England : 1990) 20060501

Title: Testosterone induces neuroprotection from oxidative stress. Effects on catalase activity and 3-nitro-L-tyrosine incorporation into alpha-tubulin in a mouse neuroblastoma cell line.

Journal: Archives italiennes de biologie 20060501

Title: Recent progress in hormonal therapy for advanced prostate cancer.

Journal: Current opinion in urology 20060501

Title: Expression of functional aromatase in the epididymis: role of androgens and LH in modulation of expression and activity.

Journal: Molecular and cellular endocrinology 20060425

Title: Fatal liver complications with flutamide.

Journal: Lancet (London, England) 20060408

Title: Hirsutism.

Journal: The New England journal of medicine 20060406

Title: Spontaneous reporting of hepatotoxicity associated with antiandrogens: data from the Spanish pharmacovigilance system.

Journal: Pharmacoepidemiology and drug safety 20060401

Title: Luteinizing hormone, follicle stimulating hormone, and gonadotropin releasing hormone mRNA expression of Xenopus laevis in response to endocrine disrupting compounds affecting reproductive biology.

Journal: General and comparative endocrinology 20060401

Title: The magnitude of early castration-induced primary tumour regression in prostate cancer does not predict clinical outcome.

Journal: European urology 20060401

Title: Dihydrotestosterone differentially modulates the mitogen-activated protein kinase and the phosphoinositide 3-kinase/Akt pathways through the nuclear and novel membrane androgen receptor in C6 cells.

Journal: Endocrinology 20060401

Title: COMPRENDO: Focus and approach.

Journal: Environmental health perspectives 20060401

Title: Use of the three-spined stickleback (Gasterosteus aculeatus) as a sensitive in vivo test for detection of environmental antiandrogens.

Journal: Environmental health perspectives 20060401

Title: Long-term, low-dose flutamide does not cause hepatotoxicity in hyperandrogenic women.

Journal: Nature clinical practice. Endocrinology & metabolism 20060401

Title: Marked sexual dimorphism of lacrimal gland peroxidase in hamster: repression by androgens and estrogens.

Journal: Biochemical and biophysical research communications 20060324

Title: Early initiation of salvage hormone therapy influences survival in patients who failed initial radiation for locally advanced prostate cancer: A secondary analysis of RTOG protocol 86-10.

Journal: International journal of radiation oncology, biology, physics 20060315

Title: Cloning and expression analysis of androgen receptor gene in chicken embryogenesis.

Journal: FEBS letters 20060306

Title: TNF-alpha-related apoptosis-inducing ligand decoy receptor DcR2 is targeted by androgen action in the rat ventral prostate.

Journal: Journal of cellular physiology 20060301

Title: A semiquantitative method for the determination of reactive metabolite conjugate levels in vitro utilizing liquid chromatography-tandem mass spectrometry and novel quaternary ammonium glutathione analogues.

Journal: Chemical research in toxicology 20060301

Title: [Effect of dihydrotestosterone on the transcriptions and expressions of Smad3 and Smad4 in LNCaP cell line].

Journal: Zhonghua nan ke xue = National journal of andrology 20060301

Title: [Impact of flutamide on sex differentiation in rats].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20060301

Title: Metabolism and hepatic toxicity of flutamide in cytochrome P450 1A2 knockout SV129 mice.

Journal: Journal of gastroenterology 20060301

Title: Androgen-induced yawning in rhesus monkey females is reversed with a nonsteroidal anti-androgen.

Journal: Hormones and behavior 20060201

Title: Discontinuous low-dose flutamide-metformin plus an oral or a transdermal contraceptive in patients with hyperinsulinaemic hyperandrogenism: normalizing effects on CRP, TNF-alpha and the neutrophil/lymphocyte ratio.

Journal: Human reproduction (Oxford, England) 20060201

Title: Mechanism of the salutary effects of flutamide on intestinal myeloperoxidase activity following trauma-hemorrhage: up-regulation of estrogen receptor-{beta}-dependent HO-1.

Journal: Journal of leukocyte biology 20060201

Title: The xenoestrogen bisphenol A in the Hershberger assay: androgen receptor regulation and morphometrical reactions indicate no major effects.

Journal: The Journal of steroid biochemistry and molecular biology 20060201

Title: The androgen 5alpha-dihydrotestosterone and its metabolite 5alpha-androstan-3beta, 17beta-diol inhibit the hypothalamo-pituitary-adrenal response to stress by acting through estrogen receptor beta-expressing neurons in the hypothalamus.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060201

Title: Unfaithfulness and promiscuity of a mutant androgen receptor in a hormone-refractory prostate cancer.

Journal: Cellular and molecular life sciences : CMLS 20060201

Title: Germ cell atypia in undescended testes hinges on the aetiology of cryptorchidism but not the abdominal location per se.

Journal: International journal of andrology 20060201

Title: A new role for androgen in testicular descent: permitting gubernacular cell proliferation in response to the neuropeptide, calcitonin gene-related peptide.

Journal: Journal of pediatric surgery 20060201

Title: Prenatal androgen blockade accelerates pubertal development in male rhesus monkeys.

Journal: Psychoneuroendocrinology 20060101

Title: Flutamide restores cardiac function after trauma-hemorrhage via an estrogen-dependent pathway through upregulation of PGC-1.

Journal: American journal of physiology. Heart and circulatory physiology 20060101

Title: Both testosterone and follicle-stimulating hormone independently inhibit spermatogonial differentiation in irradiated rats.

Journal: Endocrinology 20060101

Title: Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: nuclear translocation of androgen receptor complex with beta-catenin and T-cell factor 4 may bypass canonical Wnt signaling to down-regulate adipogenic transcription factors.

Journal: Endocrinology 20060101

Title: Long-term hormone therapy and radiation is cost-effective for patients with locally advanced prostate carcinoma.

Journal: Cancer 20060101

Title: A phase I trial of pox PSA vaccines (PROSTVAC-VF) with B7-1, ICAM-1, and LFA-3 co-stimulatory molecules (TRICOM) in patients with prostate cancer.

Journal: Journal of translational medicine 20060101

Title: Low-dose flutamide-metformin therapy for hyperinsulinemic hyperandrogenism in non-obese adolescents and women.

Journal: Human reproduction update 20060101

Title: The effects of dehydroepiandrosterone (DHEA) on in vitro spleen cell proliferation and cytokine production.

Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20060101

Title: Orchiectomy or androgen receptor blockade attenuates baroreflex-mediated bradycardia in conscious rats.

Journal: BMC pharmacology 20060101

Title: Androgen modulation of hippocampal synaptic plasticity.

Journal: Neuroscience 20060101

Title: Effects of prenatal flutamide on testicular development, androgen production and fertility in rats.

Journal: Urologia internationalis 20060101

Title: Gene expression profiling of androgen receptor antagonists in the rat fetal testis reveals few common gene targets.

Journal: Journal of biochemical and molecular toxicology 20060101

Title: [Testosterone inhibits the contractile responses to phenylephrine associated with the release of intracellular calcium in rat aorta].

Journal: Gaceta medica de Mexico 20060101

Title: The role of steroids in follicular growth.

Journal: Reproductive biology and endocrinology : RB&E 20060101

Title: Contributions of androgen and estrogen to fetal programming of ovarian dysfunction.

Journal: Reproductive biology and endocrinology : RB&E 20060101

Title: Enhanced expression of heat shock protein 27 following neoadjuvant hormonal therapy is associated with poor clinical outcome in patients undergoing radical prostatectomy for prostate cancer.

Journal: Anticancer research 20060101

Title: DHEA-induced antiproliferative effect in MCF-7 cells is androgen- and estrogen receptor-independent.

Journal: Cancer journal (Sudbury, Mass.) 20060101

Title: Non-hormonal systemic therapy in men with hormone-refractory prostate cancer and metastases: a systematic review from the Cancer Care Ontario Program in Evidence-based Care's Genitourinary Cancer Disease Site Group.

Journal: BMC cancer 20060101

Title: The origins and sequelae of abnormal neuroendocrine function in polycystic ovary syndrome.

Journal: Human reproduction update 20060101

Title: Diagnosis and management of polycystic ovary syndrome: a practical guide.

Journal: Drugs 20060101

Title: Flutamide in men with prostatic intraepithelial neoplasia: a randomized, placebo-controlled chemoprevention trial.

Journal: American journal of therapeutics 20060101

Title: The limited significance of a longer duration of neoadjuvant hormonal therapy prior to radical prostatectomy for high-risk prostate cancer in Japanese men.

Journal: Urologia internationalis 20060101

Title: Finasteride induced depression: a prospective study.

Journal: BMC clinical pharmacology 20060101

Title: Regulation of human endometrial function: mechanisms relevant to uterine bleeding.

Journal: Reproductive biology and endocrinology : RB&E 20060101

Title: Role of nonhuman primate models in the discovery and clinical development of selective progesterone receptor modulators (SPRMs).

Journal: Reproductive biology and endocrinology : RB&E 20060101

Title: Sex as a factor in conversion from laparoscopic cholecystectomy to open surgery.

Journal: JSLS : Journal of the Society of Laparoendoscopic Surgeons 20060101

Title: [Effect of combined application of the synthetic luteinizing hormone-releasing hormone agonist and nonsteroidal antiandrogen on the reproductive system of male rats].

Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20060101

Title: Thiazolidinediones and Fertility in Polycystic Ovary Syndrome (PCOS).

Journal: PPAR research 20060101

Title: The individualization of cancer therapy: the unexpected role of p53.

Journal: Transactions of the American Clinical and Climatological Association 20060101

Title: Evaluation of androgen receptor transcriptional activities of bisphenol A, octylphenol and nonylphenol in vitro.

Journal: Toxicology 20051215

Title: An in vitro approach to detect metabolite toxicity due to CYP3A4-dependent bioactivation of xenobiotics.

Journal: Toxicology 20051215

Title: Identification of steroid derivatives that function as potent antiandrogens.

Journal: International journal of cancer 20051210

Title: PGC-1 upregulation via estrogen receptors: a common mechanism of salutary effects of estrogen and flutamide on heart function after trauma-hemorrhage.

Journal: American journal of physiology. Heart and circulatory physiology 20051201

Title: Alteration of transforming growth factor-beta signaling system expression in adult rat germ cells with a chronic apoptotic cell death process after fetal androgen disruption.

Journal: Endocrinology 20051201

Title: Cancer treatment and pharmacogenetics of cytochrome P450 enzymes.

Journal: Investigational new drugs 20051201

Title: Effect of epidermal growth factor on spermatogenesis in the cryptorchid rat.

Journal: The Journal of urology 20051201

Title: Change of the cell cycle after flutamide treatment in prostate cancer cells and its molecular mechanism.

Journal: Asian journal of andrology 20051201

Title: Sex differences in juvenile rhesus macaque (Macaca mulatta) agonistic screams: life history differences and effects of prenatal androgens.

Journal: Developmental psychobiology 20051201

Title: Estrogen and testosterone use different cellular pathways to inhibit osteoclastogenesis and bone resorption.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20051201

Title: Co-activator and co-repressor interplay on the human androgen receptor.

Journal: Andrologia 20051201

Title: Comparison of the clinical efficacy of flutamide and spironolactone plus Diane 35 in the treatment of idiopathic hirsutism: a randomized controlled study.

Journal: Fertility and sterility 20051201

Title: Influence of ovariectomy and flutamide treatment on vaginal tissue and body weight.

Journal: Saudi medical journal 20051201

Title: Polycystic ovary syndrome.

Journal: Clinical evidence 20051201

Title: Androgen-dependent apoptosis in male germ cells is regulated through the proto-oncoprotein Cbl.

Journal: The Journal of cell biology 20051121

Title: Prostate cancer PET bioprobes: synthesis of [18F]-radiolabeled hydroxyflutamide derivatives.

Journal: Bioorganic & medicinal chemistry 20051115

Title: Androgen receptor modifications in prostate cancer cells upon long-termandrogen ablation and antiandrogen treatment.

Journal: International journal of cancer 20051101

Title: Characterization of a novel rat epididymal cell line to study epididymal function.

Journal: Endocrinology 20051101

Title: Induction of liver cytochrome P450 1A2 expression by flutamide in rats.

Journal: Acta pharmacologica Sinica 20051101

Title: Short-term androgen deprivation and radiotherapy for locally advanced prostate cancer: results from the Trans-Tasman Radiation Oncology Group 96.01 randomised controlled trial.

Journal: The Lancet. Oncology 20051101

Title: Imaging androgen receptor function during flutamide treatment in the LAPC9 xenograft model.

Journal: Molecular cancer therapeutics 20051101

Title: Mouse model of male germ cell apoptosis in response to a lack of hormonal stimulation.

Journal: Indian journal of experimental biology 20051101

Title: The evaluation and treatment of hirsute women.

Journal: Women's health (London, England) 20051101

Title: Androgens augment the mitogenic effects of oocyte-secreted factors and growth differentiation factor 9 on porcine granulosa cells.

Journal: Biology of reproduction 20051001

Title: Mechanism of androgen-induced thymic atrophy in the wall lizard, Hemidactylus flaviviridis: an in vitro study.

Journal: General and comparative endocrinology 20051001

Title: Expression of insulin-like factor 3 protein in the rat testis during fetal and postnatal development and in relation to cryptorchidism induced by in utero exposure to di (n-Butyl) phthalate.

Journal: Endocrinology 20051001

Title: A phase II study of nilutamide in men with prostate cancer after the failure of flutamide or bicalutamide therapy.

Journal: BJU international 20051001

Title: Clinical outcome of maximum androgen blockade using flutamide as second-line hormonal therapy for hormone-refractory prostate cancer.

Journal: BJU international 20051001

Title: Androgen receptor-mediated regulation of the alpha-subunit of the epithelial sodium channel in human kidney.

Journal: Hypertension (Dallas, Tex. : 1979) 20051001

Title: [Experience in treating advanced prostate cancer with bladder outlet obstruction].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20051001

Title: [Usefulness and positioning of MAB therapy for prostate cancer].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20051001

Title: Is combined androgen blockade with bicalutamide cost-effective compared with combined androgen blockade with flutamide?

Journal: Urology 20051001

Title: [Long term survival results in advanced prostate cancer treated with combined androgen blockade].

Journal: Zhonghua nan ke xue = National journal of andrology 20051001

Title: Predictive factors for skeletal complications in hormone-refractory prostate cancer patients with metastatic bone disease.

Journal: British journal of cancer 20050919

Title: Antiandrogens prevent stable DNA-binding of the androgen receptor.

Journal: Journal of cell science 20050915

Title: Dominant expression of androgen receptors and their functional regulation of organic anion transporter 3 in rat brain capillary endothelial cells; comparison of gene expression between the blood-brain and -retinal barriers.

Journal: Journal of cellular physiology 20050901

Title: High neutrophil count in girls and women with hyperinsulinaemic hyperandrogenism: normalization with metformin and flutamide overcomes the aggravation by oral contraception.

Journal: Human reproduction (Oxford, England) 20050901

Title: The ontogeny of the urogenital system of the spotted hyena (Crocuta crocuta Erxleben).

Journal: Biology of reproduction 20050901

Title: Anxiolytic-like actions of testosterone in the burying behavior test: role of androgen and GABA-benzodiazepine receptors.

Journal: Psychoneuroendocrinology 20050901

Title: The partial female to male sex reversal in Wnt-4-deficient females involves induced expression of testosterone biosynthetic genes and testosterone production, and depends on androgen action.

Journal: Endocrinology 20050901

Title: Circulating antiandrogenic activity in children with congenital adrenal hyperplasia during peroral flutamide treatment.

Journal: The Journal of clinical endocrinology and metabolism 20050901

Title: Antiviral effect of dehydroepiandrosterone on Japanese encephalitis virus infection.

Journal: The Journal of general virology 20050901

Title: Dehydroepiandrosterone sulfate induces acute vasodilation of porcine coronary arteries in vitro and in vivo.

Journal: Journal of cardiovascular pharmacology 20050901

Title: Late radiotherapy toxicity after prostate cancer treatment: influence of hormonal therapy.

Journal: Urology 20050901

Title: Acquisition of androgen independence by human prostate epithelial cells during arsenic-induced malignant transformation.

Journal: Environmental health perspectives 20050901

Title: Saccharomyces cerevisiae intervention for relieving flutamide-induced hepatotoxicity in male rats.

Journal: Die Pharmazie 20050901

Title: Androgens induce relaxation of contractile activity in pregnant human myometrium at term: a nongenomic action on L-type calcium channels.

Journal: Biology of reproduction 20050801

Title: Simultaneous treatment with an aromatase inhibitor and an anti-androgen decreases the likelihood of dawn song in free-living male great tits, Parus major.

Journal: Hormones and behavior 20050801

Title: Surgical trauma and immunosuppression: pathophysiology and potential immunomodulatory approaches.

Journal: Langenbeck's archives of surgery 20050801

Title: Prenatal blockade of androgen receptors reduces the number of intromissions needed to induce conditioned place preference after paced mating in female rats.

Journal: Pharmacology, biochemistry, and behavior 20050801

Title: Separating behavioral and physiological mechanisms in testosterone-mediated trade-offs.

Journal: The American naturalist 20050801

Title: Decrease in anogenital distance among male infants with prenatal phthalate exposure.

Journal: Environmental health perspectives 20050801

Title: Evaluation of general behavior, memory, learning performance, and brain sexual differentiation in F1 offspring males of rats treated with flutamide during late gestation.

Journal: The Journal of toxicological sciences 20050801

Title: Anti-androgen induced inhibition of testicular descent is associated with a decrease in sympathetic tonus.

Journal: European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie 20050801

Title: An index of local sensitivity to nonignorable drop-out in longitudinal modelling.

Journal: Statistics in medicine 20050730

Title: The structural basis of androgen receptor activation: intramolecular and intermolecular amino-carboxy interactions.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20050712

Title: Absence of hepatotoxicity after long-term, low-dose flutamide in hyperandrogenic girls and young women.

Journal: Human reproduction (Oxford, England) 20050701

Title: Androgen action on hepatic vitellogenin synthesis in the eel, Anguilla japonica is suppressed by an androgen receptor antagonist.

Journal: The Journal of steroid biochemistry and molecular biology 20050701

Title: Androgen receptor pathway in rats with autosomal dominant polycystic kidney disease.

Journal: Journal of the American Society of Nephrology : JASN 20050701

Title: Mechanism responsible for the salutary effects of flutamide on cardiac performance after trauma-hemorrhagic shock: Upregulation of cardiomyocyte estrogen receptors.

Journal: Surgery 20050701

Title: [Toxic hepatitis after flutamide treatment].

Journal: Atencion primaria 20050630

Title: Gene expression changes in rat prostate after activation or blocking of the androgen and estrogen receptor.

Journal: Molecular and cellular endocrinology 20050615

Title: Medroxyprogesterone acetate and dihydrotestosterone induce coronary hyperreactivity in intact male rhesus monkeys.

Journal: The Journal of clinical endocrinology and metabolism 20050601

Title: Changes in androgen-mediated reproductive development in male rat offspring following exposure to a single oral dose of flutamide at different gestational ages.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050601

Title: Perinatal exposure to low levels of the environmental antiandrogen vinclozolin alters sex-differentiated social play and sexual behaviors in the rat.

Journal: Environmental health perspectives 20050601

Title: The plant polyphenol butein inhibits testosterone-induced proliferation in breast cancer cells expressing aromatase.

Journal: Life sciences 20050520

Title: 5alpha-dihydrotestosterone inhibits 1alpha,25-dihydroxyvitamin D3-induced expression of CYP24 in human prostate cancer cells.

Journal: The Prostate 20050515

Title: Functional genomics may allow accurate categorization of the benzimidazole fungicide benomyl: lack of ability to act via steroid-receptor-mediated mechanisms.

Journal: Toxicology and applied pharmacology 20050515

Title: Factors regulating the timing of puberty onset in female rhesus monkeys (Macaca mulatta): role of prenatal androgens, social rank, and adolescent body weight.

Journal: Biology of reproduction 20050501

Title: Follicle-stimulating hormone regulates both Sertoli cell and spermatogonial populations in the adult photoinhibited Djungarian hamster testis.

Journal: Biology of reproduction 20050501

Title: Androgen regulation of stage-dependent cyclin D2 expression in Sertoli cells suggests a role in modulating androgen action on spermatogenesis.

Journal: Biology of reproduction 20050501

Title: Testosterone and autumn territorial behavior in male red grouse Lagopus lagopus scoticus.

Journal: Hormones and behavior 20050501

Title: Castration reduces platelet thromboxane A2 receptor density and aggregability.

Journal: QJM : monthly journal of the Association of Physicians 20050501

Title: Stimulating effects of androgen on proliferation of cultured ovarian germ cells through androgenic and estrogenic actions in embryonic chickens.

Journal: Domestic animal endocrinology 20050501

Title: Neonatal treatment of rats with diethylstilboestrol (DES) induces stromal-epithelial abnormalities of the vas deferens and cauda epididymis in adulthood following delayed basal cell development.

Journal: Reproduction (Cambridge, England) 20050501

Title: [Establishment of reporter gene-based assays for the identification of (anti) androgenic effects of chemicals in CHO cells].

Journal: Wei sheng yan jiu = Journal of hygiene research 20050501

Title: Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate cancer xenograft model.

Journal: Journal of medicinal chemistry 20050421

Title: Novel non-steroidal/non-anilide type androgen antagonists: discovery of 4-substituted pyrrole-2-carboxamides as a new scaffold for androgen receptor ligands.

Journal: Bioorganic & medicinal chemistry 20050415

Title: Survivin mediates resistance to antiandrogen therapy in prostate cancer.

Journal: Oncogene 20050407

Title: Potential estrogenic and antiandrogenic effects of permethrin in rats.

Journal: The Journal of reproduction and development 20050401

Title: Androgen-regulated transcripts in the neonatal mouse testis as determined through microarray analysis.

Journal: Biology of reproduction 20050401

Title: Organizational role for testosterone and estrogen on adult hypothalamic-pituitary-adrenal axis activity in the male rat.

Journal: Endocrinology 20050401

Title: Androgens stimulate human vascular smooth muscle cell proteoglycan biosynthesis and increase lipoprotein binding.

Journal: Endocrinology 20050401

Title: Effects of in utero and lactational exposure to flutamide in SD rats: comparison of the effects of administration periods.

Journal: Toxicology 20050401

Title: Hormonal influences on sexually differentiated behavior in nonhuman primates.

Journal: Frontiers in neuroendocrinology 20050401

Title: In vivo and in vitro exposures of carp and carp tissues to graded concentrations of endocrine disrupting chemicals.

Journal: Annals of the New York Academy of Sciences 20050401

Title: Effects of male and female sex steroids on the development of normal and the transient Froriep's dorsal root ganglia of the chick embryo.

Journal: Brain research. Developmental brain research 20050322

Title: Application of an antiandrogen during pregnancy infantilizes the male offsprings' behaviour.

Journal: Behavioural brain research 20050307

Title: The female intestine is more resistant than the male intestine to gut injury and inflammation when subjected to conditions associated with shock states.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20050301

Title: Androgens and postmeiotic germ cells regulate claudin-11 expression in rat Sertoli cells.

Journal: Endocrinology 20050301

Title: Glutathione peroxidase activity in cell cultures from different regions of human epididymis.

Journal: Asian journal of andrology 20050301

Title: Reversibility of androgen deprivation therapy in patients with prostate cancer.

Journal: The Journal of urology 20050301

Title: Positron tomographic assessment of androgen receptors in prostatic carcinoma.

Journal: European journal of nuclear medicine and molecular imaging 20050301

Title: Antihypertensive effects of flutamide in rats that are exposed to a low-protein diet in utero.

Journal: American journal of obstetrics and gynecology 20050301

Title: [High intensity focused ultrasound combined with endocrine therapy in treating prostate cancer].

Journal: Zhonghua nan ke xue = National journal of andrology 20050301

Title: [Alfa-blockade with doxazosin vs tamsulozin in combination of intermittent androgen blockade in patients with prostate cancer].

Journal: Georgian medical news 20050301

Title: Combined androgen blockade: the case for bicalutamide.

Journal: Clinical prostate cancer 20050301

Title: Three-dimensional structure-activity relationships of nonsteroidal ligands in complex with androgen receptor ligand-binding domain.

Journal: Journal of medicinal chemistry 20050224

Title: Toxic and hormonal effects of polychlorinated biphenyls on cultured testicular germ cells of embryonic chickens.

Journal: Toxicology letters 20050215

Title: Influence of gonadal steroids on the glial fibrillary acidic protein-immunoreactive astrocyte population in young rat hippocampus.

Journal: Journal of neuroscience research 20050215

Title: Middle-age male mice have increased severity of experimental autoimmune encephalomyelitis and are unresponsive to testosterone therapy.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20050215

Title: The influence of androgen deprivation therapy on metabolism in patients with prostate cancer.

Journal: The Journal of clinical endocrinology and metabolism 20050201

Title: Antiandrogenic effects in short-term in vivo studies of the fungicide fenarimol.

Journal: Toxicology 20050201

Title: Effects of sex steroids and their inhibitors on endocrine parameters and gender growth differences in Eurasian perch (Perca fluviatilis) juveniles.

Journal: Steroids 20050201

Title: Effects of the androgen antagonist flutamide and the serotonin reuptake inhibitor citalopram in bulimia nervosa: a placebo-controlled pilot study.

Journal: Journal of clinical psychopharmacology 20050201

Title: [Hormonal therapy for prostatic cancer--state of the art].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20050201

Title: [Neoadjuvant hormonal therapy for prostate cancer].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20050201

Title: Gubernacular cell division in different rodent models of cryptorchidism supports indirect androgenic action via the genitofemoral nerve.

Journal: Journal of pediatric surgery 20050201

Title: Anemia under androgen deprivation: influence of flutamide, cyproteroneacetate and orchiectomy on the erythropoietin system.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20050201

Title: 19-Nortestosterone influences neural stem cell proliferation and neurogenesis in the rat brain.

Journal: The European journal of neuroscience 20050201

Title: Coagulopathy, following medical therapy, for carcinoma of the prostate.

Journal: Hematology (Amsterdam, Netherlands) 20050201

Title: Chlorambucil and lomustine (CL56) in absolute hormone refractory prostate cancer: re-induction of endocrine sensitivity an unexpected finding.

Journal: British journal of cancer 20050117

Title: Role of endogenous testosterone in myocardial proinflammatory and proapoptotic signaling after acute ischemia-reperfusion.

Journal: American journal of physiology. Heart and circulatory physiology 20050101

Title: Flutamide-metformin plus ethinylestradiol-drospirenone for lipolysis and antiatherogenesis in young women with ovarian hyperandrogenism: the key role of metformin at the start and after more than one year of therapy.

Journal: The Journal of clinical endocrinology and metabolism 20050101

Title: Development of androgen- and estrogen-responsive bioassays, members of a panel of human cell line-based highly selective steroid-responsive bioassays.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050101

Title: Marked hyperglycemia after androgen-deprivation therapy for prostate cancer and usefulness of pioglitazone for its treatment.

Journal: Metabolism: clinical and experimental 20050101

Title: Homologous up-regulation of androgen receptor expression by androgen in vascular smooth muscle cells.

Journal: Hormone research 20050101

Title: A comparison of in vitro and in vivo EDSTAC test battery results for detecting antiandrogenic activity.

Journal: Toxicology and applied pharmacology 20050101

Title: Evidence that androgens and oestrogens, as well as follicle-stimulating hormone, can alter Sertoli cell number in the neonatal rat.

Journal: The Journal of endocrinology 20050101

Title: Stable expression of constitutively-activated STAT3 in benign prostatic epithelial cells changes their phenotype to that resembling malignant cells.

Journal: Molecular cancer 20050101

Title: Small cell carcinoma of the prostate with hypercalcemia.

Journal: International journal of urology : official journal of the Japanese Urological Association 20050101

Title: Paediatric management of endocrine complications in McCune-Albright syndrome.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20050101

Title: Effect of testosterone replacement or duration of castration on baroreflex bradycardia in conscious rats.

Journal: BMC pharmacology 20050101

Title: Androgen and androgen receptor antagonist responsive primary African-American benign prostate epithelial cell line.

Journal: Anticancer research 20050101

Title: Impact of hormone therapy on acute radiotherapy toxicity in the treatment of prostate cancer.

Journal: Prostate cancer and prostatic diseases 20050101

Title: Mechanisms of ensemble failure of the male gonadal axis in aging.

Journal: Journal of endocrinological investigation 20050101

Title: Response of T lymphocyte populations in prostate cancer patients undergoing radiotherapy: influence of neoajuvant total androgen suppression.

Journal: Anticancer research 20050101

Title: [Severe acute hepatitis due to flutamide and elevated CA 19.9].

Journal: Gastroenterologia y hepatologia 20050101

Title: Intermittent androgen castration: a biological reality during intermittent treatment in metastatic prostate cancer?

Journal: Urologia internationalis 20050101

Title: Androgen dependent mammary gland virilism in rats given the selective estrogen receptor modulator LY2066948 hydrochloride.

Journal: Toxicologic pathology 20050101

Title: Biochemical characterization of the Arctic char (Salvelinus alpinus) ovarian progestin membrane receptor.

Journal: Reproductive biology and endocrinology : RB&E 20050101

Title: Pharmacological profile of 9,11-dehydrocortexolone 17alpha-butyrate (CB-03-04), a new androgen antagonist with antigonadotropic activity.

Journal: Arzneimittel-Forschung 20050101

Title: Microscopic polyangiitis complicated by the development of prostate cancer and flutamide-induced hepatitis.

Journal: International urology and nephrology 20050101

Title: Gefitinib (Iressa, ZD1839) and tyrosine kinase inhibitors: the wave of the future in cancer therapy.

Journal: Cancer nursing 20050101

Title: [Administration of 1 alpha-OH vitamin D3 and calcium prevents bone mass loss in patients with advanced prostatic carcinoma after orchidectomy treated with complete androgenic blockade].

Journal: Endokrynologia Polska 20050101

Title: Dose-dependent transitions in mechanisms of toxicity: case studies.

Journal: Toxicology and applied pharmacology 20041215

Title: Comparison of the pharmacological effects of a novel selective androgen receptor modulator, the 5alpha-reductase inhibitor finasteride, and the antiandrogen hydroxyflutamide in intact rats: new approach for benign prostate hyperplasia.

Journal: Endocrinology 20041201

Title: Effect of anti-estrogens on the androgen receptor activity and cell proliferation in prostate cancer cells.

Journal: Urological research 20041201

Title: Anemia in patients on combined androgen block therapy for prostate cancer.

Journal: Asian journal of andrology 20041201

Title: Recent advances in the treatment of juvenile angiofibroma.

Journal: Current opinion in otolaryngology & head and neck surgery 20041201

Title: Exogenous testosterone inhibits several forms of male parental behavior and stimulates song in a monogamous songbird: the blue-headed vireo (Vireo solitarius).

Journal: Hormones and behavior 20041201

Title: Randomized trial of leuprorelin and flutamide in male patients with hepatocellular carcinoma treated with tamoxifen.

Journal: Hepatology (Baltimore, Md.) 20041201

Title: Bone mineral density in patients with prostate cancer without bone metastases treated with intermittent androgen suppression.

Journal: Urology 20041201

Title: Evaluation of the model anti-androgen flutamide for assessing the mechanistic basis of responses to an androgen in the fathead minnow (Pimephales promelas).

Journal: Environmental science & technology 20041201

Title: Combined androgen blockade in the management of advanced prostate cancer: a sensible or ostensible approach.

Journal: International journal of urology : official journal of the Japanese Urological Association 20041201

Title: Phosphorylation of p70s6 kinase is implicated in androgen-induced levator ani muscle anabolism in castrated rats.

Journal: The Journal of steroid biochemistry and molecular biology 20041201

Title: Effects of flutamide on sex maturation and behavior of offspring born to female rats treated during late pregnancy.

Journal: The Journal of toxicological sciences 20041201

Title: Polycystic ovary syndrome.

Journal: Clinical evidence 20041201

Title: Characterization of responses to the antiandrogen flutamide in a short-term reproduction assay with the fathead minnow.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20041118

Title: The combined antiandrogenic effects of five commonly used pesticides.

Journal: Toxicology and applied pharmacology 20041115

Title: Testosterone induces cytoprotection by activating ATP-sensitive K+ channels in the cardiac mitochondrial inner membrane.

Journal: Circulation 20041109

Title: Studies of targeting and intracellular trafficking of an anti-androgen doxorubicin-formaldehyde conjugate in PC-3 prostate cancer cells bearing androgen receptor-GFP chimera.

Journal: Journal of medicinal chemistry 20041104

Title: The effects of the reported active metabolite of methoxychlor, 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane, on testosterone formation by cultured Leydig cells from young adult rats.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20041101

Title: Androgen receptor is targeted to distinct subcellular compartments in response to different therapeutic antiandrogens.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041101

Title: Optimization of formulation parameters for the preparation of flutamide liposomes by 3(3) factorial 26-term logit model.

Journal: Pharmaceutical development and technology 20041101

Title: Epirubicin carboplatin and 5-fluorouracil (ECarboF) chemotherapy in metastatic hormone refractory prostate cancer.

Journal: British journal of cancer 20041018

Title: Successful detection of (anti-)androgenic and aromatase inhibitors in pre-spawning adult fathead minnows (Pimephales promelas) using easily measured endpoints of sexual development.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20041018

Title: Endocrine-disrupting activity in carbendazim-induced reproductive and developmental toxicity in rats.

Journal: Journal of toxicology and environmental health. Part A 20041008

Title: Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-beta ligands.

Journal: Journal of medicinal chemistry 20041007

Title: Recruitment of beta-catenin by wild-type or mutant androgen receptors correlates with ligand-stimulated growth of prostate cancer cells.

Journal: Molecular endocrinology (Baltimore, Md.) 20041001

Title: Targeted inhibition of the epidermal growth factor receptor-tyrosine kinase by ZD1839 ('Iressa') induces cell-cycle arrest and inhibits proliferation in prostate cancer cells.

Journal: Journal of cellular physiology 20041001

Title: Mammalian target of rapamycin and 3-phosphatidylinositol 3-kinase pathway inhibition enhances growth inhibition of transforming growth factor-beta1 in prostate cancer cells.

Journal: The Journal of urology 20041001

Title: Hirsutism and acne in polycystic ovary syndrome.

Journal: Best practice & research. Clinical obstetrics & gynaecology 20041001

Title: The mitochondrial-dependent pathway is chronically affected in testicular germ cell death in adult rats exposed in utero to anti-androgens.

Journal: The Journal of endocrinology 20041001

Title: [Role of androgens in the renal production of 20-hydroxyeicosatetraenoic acid in spontaneously hypertensive rats].

Journal: Nihon Jinzo Gakkai shi 20041001

Title: Androgen dependent development of a modified anal fin, gonopodium, as a model to understand the mechanism of secondary sexual character expression in vertebrates.

Journal: FEBS letters 20040924

Title: Is there a role for chemotherapy in prostate cancer?

Journal: British journal of cancer 20040913

Title: Effects of dehydroepiandrosterone and flutamide on hippocampal CA1 spine synapse density in male and female rats: implications for the role of androgens in maintenance of hippocampal structure.

Journal: Endocrinology 20040901

Title: Gonadal hormones and frontocortical expression of vascular endothelial growth factor in male stroke-prone, spontaneously hypertensive rats, a model for attention-deficit/hyperactivity disorder.

Journal: Endocrinology 20040901

Title: One year follow-up study of the association between chemical castration, sex hormones, beta-amyloid, memory and depression in men.

Journal: Psychoneuroendocrinology 20040901

Title: The effect of combined androgen ablation on the expression of alpha1A-adrenergic receptor in the human prostate.

Journal: The Prostate 20040901

Title: Report of a multicenter Canadian phase III randomized trial of 3 months vs. 8 months neoadjuvant androgen deprivation before standard-dose radiotherapy for clinically localized prostate cancer.

Journal: International journal of radiation oncology, biology, physics 20040901

Title: Dehydroepiandrosterone increases endothelial cell proliferation in vitro and improves endothelial function in vivo by mechanisms independent of androgen and estrogen receptors.

Journal: The Journal of clinical endocrinology and metabolism 20040901

Title: Flutamide-metformin plus ethinylestradiol-drospirenone for lipolysis and antiatherogenesis in young women with ovarian hyperandrogenism: the key role of early, low-dose flutamide.

Journal: The Journal of clinical endocrinology and metabolism 20040901

Title: Combination hormonal therapy: a reassessment within advanced prostate cancer.

Journal: Prostate cancer and prostatic diseases 20040901

Title: Interstitial pneumonitis related to flutamide monotherapy for prostate cancer.

Journal: International journal of urology : official journal of the Japanese Urological Association 20040901

Title: Monotherapy in advanced prostate cancer: an overview.

Journal: Experimental oncology 20040901

Title: [Treatment of spinal and bulbar muscular atrophy].

Journal: No to shinkei = Brain and nerve 20040901

Title: Metformin versus flutamide in the treatment of metabolic consequences of non-obese young women with polycystic ovary syndrome: a randomized prospective study.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20040901

Title: Cytochrome P450 CYP1B1 activity in renal cell carcinoma.

Journal: British journal of cancer 20040831

Title: 6-month androgen suppression plus radiation therapy vs radiation therapy alone for patients with clinically localized prostate cancer: a randomized controlled trial.

Journal: JAMA 20040818

Title: Functional domain and motif analyses of androgen receptor coregulator ARA70 and its differential expression in prostate cancer.

Journal: The Journal of biological chemistry 20040806

Title: Testosterone-induced coronary vasodilatation occurs via a non-genomic mechanism: evidence of a direct calcium antagonism action.

Journal: Clinical science (London, England : 1979) 20040801

Title: Flutamide-metformin plus an oral contraceptive (OC) for young women with polycystic ovary syndrome: switch from third- to fourth-generation OC reduces body adiposity.

Journal: Human reproduction (Oxford, England) 20040801

Title: Letter to the Editor; Re: Wirth MP, Weissbach L, Marx F-J, Heckl W, Jellinghaus W, Riedmiller H, Noack B, Hinke A, Froehner M. Prospective randomized trial comparing flutamide as adjuvant treatment versus observation after radical prostatectomy for locally advanced, lymph node-negative prostate cancer. Eur Urol 2004;45:267-70.

Journal: European urology 20040801

Title: Osteoporosis and spinal fractures in men with prostate cancer: risk factors and effects of androgen deprivation therapy.

Journal: The Journal of urology 20040801

Title: Re: The effects of combined androgen blockade on cognitive function during the first cycle of intermittent androgen suppression in patients with prostate cancer.

Journal: The Journal of urology 20040801

Title: Combined modality treatment in the management of high-risk prostate cancer.

Journal: International journal of radiation oncology, biology, physics 20040801

Title: Intermittent androgen suppression for locally advanced and metastatic prostate cancer: preliminary report of a prospective multicenter study.

Journal: Urology 20040801

Title: Evaluation for reliability and feasibility of the draft protocol for the enhanced rat 28-day subacute study (OECD Guideline 407) using androgen antagonist flutamide.

Journal: Toxicology 20040715

Title: Dihydrotestosterone may inhibit hypothalamo-pituitary-adrenal activity by acting through estrogen receptor in the male mouse.

Journal: Neuroscience letters 20040715

Title: The synthesis of glycoprotein Po and peripheral myelin protein 22 in sciatic nerve of male rats is modulated by testosterone metabolites.

Journal: Brain research. Molecular brain research 20040705

Title: Interactions between androgen and growth factors in granulosa cell subtypes of porcine antral follicles.

Journal: Biology of reproduction 20040701

Title: Comparison of anti-androgenic activity of flutamide, vinclozolin, procymidone, linuron, and p, p'-DDE in rodent 10-day Hershberger assay.

Journal: Toxicology 20040701

Title: Solid-state solubility influences encapsulation and release of hydrophobic drugs from PLGA/PLA nanoparticles.

Journal: Journal of pharmaceutical sciences 20040701

Title: Reproductive disorders in pubertal and adult phase of the male rats exposed to vinclozolin during puberty.

Journal: The Journal of veterinary medical science 20040701

Title: [Effectiveness of flutamide alone or combined with oral contraceptives in the treatment of hirsutism in women].

Journal: Revista medica de Chile 20040701

Title: Hormonal impact of the 17alpha-hydroxylase/C(17,20)-lyase inhibitor abiraterone acetate (CB7630) in patients with prostate cancer.

Journal: British journal of cancer 20040614

Title: Serum levels of IL-6 and TNF-alpha correlate with clinicopathological features and patient survival in patients with prostate cancer.

Journal: British journal of cancer 20040614

Title: Estrogen and androgen protection of human neurons against intracellular amyloid beta1-42 toxicity through heat shock protein 70.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040609

Title: Effect of keratinocyte growth factor and activin on cell growth in the human prostatic cancer cell line LNCaP.

Journal: World journal of urology 20040601

Title: Differential effect of small ubiquitin-like modifier (SUMO)-ylation of the androgen receptor in the control of cooperativity on selective versus canonical response elements.

Journal: Molecular endocrinology (Baltimore, Md.) 20040601

Title: The characterization and hormonal regulation of kidney androgen-regulated protein (Kap)-luciferase transgenic mice.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20040601

Title: Evidence that inhibited prostatic epithelial bud formation in 2,3,7,8-tetrachlorodibenzo-p-dioxin-exposed C57BL/6J fetal mice is not due to interruption of androgen signaling in the urogenital sinus.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20040601

Title: Flutamide induces ultrastructural changes in spermatids and the ectoplasmic specialization between the Sertoli cell and spermatids in mouse testes.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20040601

Title: Androgen receptor blockade in the MPOA or VMN: effects on male sociosexual behaviors.

Journal: Physiology & behavior 20040601

Title: Colonic toxicity of administered drugs and chemicals.

Journal: The American journal of gastroenterology 20040601

Title: Flutamide or thalidomide?

Journal: Nursing 20040601

Title: Divergent roles for estrogens and androgens in the expression of female goat sexual behavior.

Journal: Hormones and behavior 20040601

Title: [Liver toxicity associated with flutamide].

Journal: Anales de medicina interna (Madrid, Spain : 1984) 20040601

Title: Cost-effective therapy in patients with idiopathic hirsutism.

Journal: Expert review of pharmacoeconomics & outcomes research 20040601

Title: Determination of celecoxib in human plasma by high-performance liquid chromatography.

Journal: Journal of pharmaceutical and biomedical analysis 20040528

Title: Spinal and bulbar muscular atrophy: ligand-dependent pathogenesis and therapeutic perspectives.

Journal: Journal of molecular medicine (Berlin, Germany) 20040501

Title: Influence of androgen deprivation therapy on volume of anatomic zones of prostate in patients with prostate cancer using magnetic resonance imaging.

Journal: Urology 20040501

Title: The use of flutamide as a single antiandrogen treatment for hormone-refractory prostate cancer.

Journal: BJU international 20040501

Title: Medical treatment regimens of hirsutism.

Journal: Reproductive biomedicine online 20040501

Title: Testosterone and energy metabolism in the estuarine mysid Neomysis integer (Crustacea: Mysidacea) following exposure to endocrine disruptors.

Journal: Environmental toxicology and chemistry 20040501

Title: Is photopatch testing useful in the investigation of photosensitivity due to flutamide?

Journal: Contact dermatitis 20040501

Title: Which treatment options should be used in adolescents with polycystic ovary syndrome?

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20040501

Title: The selection of hormonal therapy in prostate cancer: who, when, and for how long?

Journal: Journal of the National Comprehensive Cancer Network : JNCCN 20040501

Title: Effects of tamoxifen, 17α-ethynylestradiol, flutamide, and methyltestosterone on plasma vitellogenin levels of male and female Japanese medaka (Oryzias latipes).

Journal: Environmental toxicology and pharmacology 20040501

Title: Effect of organochlorine pesticides on human androgen receptor activation in vitro.

Journal: Toxicology and applied pharmacology 20040415

Title: Fatal acute tumor lysis syndrome, hepatic encephalopathy and flare phenomenon following combined androgen blockade.

Journal: The Journal of urology 20040401

Title: Metastatic prostate cancer treated by flutamide versus cyproterone acetate. Final analysis of the 'European Organization for Research and Treatment of Cancer' (EORTC) Protocol 30892.

Journal: European urology 20040401

Title: Phase I-II trial evaluating combined intensity-modulated radiotherapy and in situ gene therapy with or without hormonal therapy in treatment of prostate cancer-interim report on PSA response and biopsy data.

Journal: International journal of radiation oncology, biology, physics 20040401

Title: Ethinylestradiol-drospirenone, flutamide-metformin, or both for adolescents and women with hyperinsulinemic hyperandrogenism: opposite effects on adipocytokines and body adiposity.

Journal: The Journal of clinical endocrinology and metabolism 20040401

Title: Plasma lipoprotein profile in the male cynomolgus monkey under normal, hypogonadal, and combined androgen blockade conditions.

Journal: The Journal of clinical endocrinology and metabolism 20040401

Title: Changes in fat and lean body mass during androgen-deprivation therapy for prostate cancer.

Journal: Urology 20040401

Title: Testosterone promotes apoptotic damage in human renal tubular cells.

Journal: Kidney international 20040401

Title: Enterocolic lymphocytic phlebitis with lymphocytic colitis, lymphocytic appendicitis, and lymphocytic enteritis.

Journal: The American journal of surgical pathology 20040401

Title: Flutamide as a preoperative treatment in juvenile angiofibroma (JA) with intracranial invasion: report of 7 cases.

Journal: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20040401

Title: Tissue alterations in the Guinea pig lateral prostate following antiandrogen flutamide therapy.

Journal: Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al 20040401

Title: Serum prostate specific antigen levels in women with polycystic ovary syndrome and the effect of flutamide+desogestrel/ethinyl estradiol combination.

Journal: Journal of endocrinological investigation 20040401

Title: The use of hormonal therapy with radiotherapy for prostate cancer: analysis of prospective randomised trials.

Journal: British journal of cancer 20040308

Title: Feedback inhibition of steroidogenic acute regulatory protein expression in vitro and in vivo by androgens.

Journal: Endocrinology 20040301

Title: Morphological features of external genitalia in hypospadiac rat model: 3-dimensional analysis.

Journal: The Journal of urology 20040301

Title: Regulation of mouse renal CYP2J5 expression by sex hormones.

Journal: Molecular pharmacology 20040301

Title: [Recurrent ischemic strokes secondary to acquired hypercoagulability in a patient with prostatic adenocarcinoma].

Journal: Neurologia (Barcelona, Spain) 20040301

Title: [Toxic hepatitis and liver failure under therapy with flutamide].

Journal: Der Internist 20040301

Title: Biochemical remission after resection of prostate cancer lung metastasis.

Journal: Urology 20040301

Title: Prospective randomized trial comparing flutamide as adjuvant treatment versus observation after radical prostatectomy for locally advanced, lymph node-negative prostate cancer.

Journal: European urology 20040301

Title: [Examination of the change in plasma concentration of OH-flutamide in low-dose flutamide (250 mg/day) monotherapy for prostate cancer patients].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20040301

Title: An evaluation of bicalutamide in the treatment of prostate cancer.

Journal: Clinical prostate cancer 20040301

Title: [A mouse model of hypospadias induced by flutamide].

Journal: Zhonghua nan ke xue = National journal of andrology 20040301

Title: Anticonvulsant activity of the testosterone-derived neurosteroid 3alpha-androstanediol.

Journal: Neuroreport 20040301

Title: Dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) inhibit the apoptosis in human peripheral blood lymphocytes.

Journal: The Journal of steroid biochemistry and molecular biology 20040301

Title: Toxic hepatitis after sequential administration of flutamide and cyproterone acetate.

Journal: Digestive diseases and sciences 20040301

Title: Ectopic expression of the amino-terminal peptide of androgen receptor leads to androgen receptor dysfunction and inhibition of androgen receptor-mediated prostate cancer growth.

Journal: Molecular and cellular endocrinology 20040212

Title: Androgen contributes to gender-related cardiac hypertrophy and fibrosis in mice lacking the gene encoding guanylyl cyclase-A.

Journal: Endocrinology 20040201

Title: Chemohormonal therapy as primary treatment for metastatic prostate cancer: a randomized study of estramustine phosphate plus luteinizing hormone-releasing hormone agonist versus flutamide plus luteinizing hormone-releasing hormone agonist.

Journal: International journal of urology : official journal of the Japanese Urological Association 20040201

Title: Alternative antiandrogens to treat prostate cancer relapse after initial hormone therapy.

Journal: The Journal of urology 20040201

Title: Direct gastrointestinal toxicity of flutamide: comparison of irradiated and nonirradiated cases.

Journal: The Journal of urology 20040201

Title: Effect of flutamide and metformin administered alone or in combination in dieting obese women with polycystic ovary syndrome.

Journal: Clinical endocrinology 20040201

Title: Antagonists of growth hormone-releasing hormone (GH-RH) enhance tumour growth inhibition induced by androgen deprivation in human MDA-Pca-2b prostate cancers.

Journal: European journal of cancer (Oxford, England : 1990) 20040201

Title: Computer based receptogram approach: an objective way of assessing immunohistochemistry of androgen receptor staining and its correlation with hormonal response in metastatic carcinoma of prostate.

Journal: Journal of clinical pathology 20040201

Title: Tibolone and its metabolites induce antimitogenesis in human coronary artery smooth muscle cells: role of estrogen, progesterone, and androgen receptors.

Journal: The Journal of clinical endocrinology and metabolism 20040201

Title: Androgen inhibition of MAP kinase pathway and Elk-1 activation in proliferating osteoblasts.

Journal: Journal of molecular endocrinology 20040201

Title: Physiological levels of 5 alpha-dihydrotestosterone depress wound immune function and impair wound healing following trauma-hemorrhage.

Journal: Archives of surgery (Chicago, Ill. : 1960) 20040201

Title: The treatment of polycystic ovary syndrome.

Journal: Minerva ginecologica 20040201

Title: [The antiandrogenic effect of dimethachlon and its mechanism].

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20040201

Title: Widespread vitiligo after erythroderma caused by photosensitivity to flutamide.

Journal: Contact dermatitis 20040201

Title: Effects of the antiandrogen flutamide on the expression of protein kinase C isoenzymes in LNCaP and PC3 human prostate cancer cells.

Journal: Bioscience reports 20040201

Title: The effects of combined aromatase inhibitor and anti-androgen on male territorial aggression in a tropical population of rufous-collared sparrows, Zonotrichia capensis.

Journal: General and comparative endocrinology 20040115

Title: Regulating the tumor suppressor gene maspin in breast cancer cells: a potential mechanism for the anticancer properties of tamoxifen.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040115

Title: Randomized Phase II trial assessing estramustine and vinblastine combination chemotherapy vs estramustine alone in patients with progressive hormone-escaped metastatic prostate cancer.

Journal: British journal of cancer 20040112

Title: Androgen-sensitive changes in regulation of restraint-induced adrenocorticotropin secretion between early and late puberty in male rats.

Journal: Endocrinology 20040101

Title: Prognosis of stage pT0 after prolonged neoadjuvant endocrine therapy of prostate cancer: a matched-pair analysis.

Journal: European urology 20040101

Title: Gene expression analysis of human prostate carcinoma during hormonal therapy identifies androgen-responsive genes and mechanisms of therapy resistance.

Journal: The American journal of pathology 20040101

Title: Involvement of serotoninergic mechanism in analgesia by castration and flutamide, a testosterone antagonist, in the rat formalin test.

Journal: Pharmacology, biochemistry, and behavior 20040101

Title: Valproic acid is known to cause hypospadias in man but does not reduce anogenital distance or causes hypospadias in rats.

Journal: Basic & clinical pharmacology & toxicology 20040101

Title: Antiandrogen monotherapy: recommendations for the treatment of prostate cancer.

Journal: Urologia internationalis 20040101

Title: Proteasome inhibitors and their combination with antiandrogens: effects on apoptosis, cellular proliferation and viability of prostatic adenocarcinoma cell cultures.

Journal: Prostate cancer and prostatic diseases 20040101

Title: Flutamide suppresses adrenal steroidogenesis but has no effect on insulin resistance and secretion and lipid levels in overweight women with polycystic ovary syndrome.

Journal: Gynecologic and obstetric investigation 20040101

Title: Male breast adenocarcinoma in a prostate cancer patient following prolonged anti-androgen monotherapy.

Journal: Anticancer research 20040101

Title: Chronic effects of flutamide in male beagle dogs.

Journal: Toxicologic pathology 20040101

Title: Flutamide administration at 500 mg daily has similar effects on serum testosterone to 750 mg daily.

Journal: Journal of andrology 20040101

Title: Effect of the anti-androgenic endocrine disruptor vinclozolin on embryonic testis cord formation and postnatal testis development and function.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20040101

Title: Anogenital distance in human male and female newborns: a descriptive, cross-sectional study.

Journal: Environmental health : a global access science source 20040101

Title: Potential action of androstenedione on the proliferation and apoptosis of stromal endometrial cells.

Journal: Reproductive biology and endocrinology : RB&E 20040101

Title: Effect of androgens on sexual differentiation of pituitary gamma-aminobutyric acid receptor subunit GABA(B) expression.

Journal: Neuroendocrinology 20040101

Title: Hepatotoxicity induced by antiandrogens: a review of the literature.

Journal: Urologia internationalis 20040101

Title: Biological profile of cortexolone 17alpha-propionate (CB-03-01), a new topical and peripherally selective androgen antagonist.

Journal: Arzneimittel-Forschung 20040101

Title: [Experience with therapy of prostate cancer in the Primorye Territory].

Journal: Voprosy onkologii 20040101

Title: Development of vitellogenin assay for endocrine disrupters using medaka (Oryzias latipes).

Journal: Environmental sciences : an international journal of environmental physiology and toxicology 20040101

Title: Practical approach to the hormonal treatment of acne.

Journal: Journal of cutaneous medicine and surgery 20040101

Title: Hormonal treatment of acne: review of current best evidence.

Journal: Journal of cutaneous medicine and surgery 20040101

Title: Hormonal therapy of acne.

Journal: Journal of cutaneous medicine and surgery 20040101

Title: Estrogen and androgen regulation of plasma membrane calcium pump activity in immortalized distal tubule kidney cells.

Journal: Molecular and cellular endocrinology 20031230

Title: Indole-3-carbinol induces a G1 cell cycle arrest and inhibits prostate-specific antigen production in human LNCaP prostate carcinoma cells.

Journal: Cancer 20031201

Title: Testosterone decreases the potential for song plasticity in adult male zebra finches.

Journal: Hormones and behavior 20031201

Title: Regulatory roles of androgens in cutaneous wound healing.

Journal: Thrombosis and haemostasis 20031201

Title: [Progress in researches on drugs for prostate cancer].

Journal: Zhonghua nan ke xue = National journal of andrology 20031201

Title: Antiandrogen-associated hepatotoxicity in the management of advanced prostate cancer.

Journal: Journal of the Chinese Medical Association : JCMA 20031201

Title: Clinical strategies in the management of biochemical recurrence after radical prostatectomy.

Journal: Clinical prostate cancer 20031201

Title: Rational design and synthesis of androgen receptor-targeted nonsteroidal anti-androgen ligands for the tumor-specific delivery of a doxorubicin-formaldehyde conjugate.

Journal: Journal of medicinal chemistry 20031120

Title: Effects of imatinib mesylate (STI571, Glivec) on the pharmacokinetics of simvastatin, a cytochrome p450 3A4 substrate, in patients with chronic myeloid leukaemia.

Journal: British journal of cancer 20031117

Title: The effects of combined androgen blockade on cognitive function during the first cycle of intermittent androgen suppression in patients with prostate cancer.

Journal: The Journal of urology 20031101

Title: Androgen dependent regulation of bacillus Calmette-Guerin induced interleukin-6 expression in human transitional carcinoma cell lines.

Journal: The Journal of urology 20031101

Title: Phase III trial of long-term adjuvant androgen deprivation after neoadjuvant hormonal cytoreduction and radiotherapy in locally advanced carcinoma of the prostate: the Radiation Therapy Oncology Group Protocol 92-02.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031101

Title: The use of flutamide as a single antiandrogen treatment for hormone-refractory prostate cancer.

Journal: BJU international 20031101

Title: Combination of low-dose flutamide and finasteride for PSA-only recurrent prostate cancer after primary therapy.

Journal: Urology 20031101

Title: Hormonal and morphologic evaluation of the effects of antiandrogens on the blood supply of the rat prostate.

Journal: Urology 20031101

Title: Effect of dihydrotestosterone on pituitary follicle-stimulating hormone isoforms in adult male rats treated with a gonadotropin-releasing hormone antagonist.

Journal: Neuroendocrinology 20031101

Title: A role for the androgen receptor in the endometrial antiproliferative effects of progesterone antagonists.

Journal: Steroids 20031101

Title: Cholestatic jaundice as a paraneoplastic manifestation of prostate adenocarcinoma.

Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20031101

Title: Identification and prediction of promiscuous aggregating inhibitors among known drugs.

Journal: Journal of medicinal chemistry 20031009

Title: Sexually dimorphic roles of steroid hormone receptor signaling in gonadal tumorigenesis.

Journal: Molecular endocrinology (Baltimore, Md.) 20031001

Title: Interactions of androgens, green tea catechins and the antiandrogen flutamide with the external glucose-binding site of the human erythrocyte glucose transporter GLUT1.

Journal: British journal of pharmacology 20031001

Title: Long-term outcome of antiandrogen monotherapy in advanced prostate carcinoma: 12-year results of a phase II study.

Journal: BJU international 20031001

Title: Metabolite profiles of flutamide in serum from patients with flutamide-induced hepatic dysfunction.

Journal: Biological & pharmaceutical bulletin 20031001

Title: Prostate carcinoma presenting as multiple pulmonary nodules in an asymptomatic patient with a history of testicular nonseminomatous germ cell tumor.

Journal: Urology 20031001

Title: Flutamide-metformin therapy to reduce fat mass in hyperinsulinemic ovarian hyperandrogenism: effects in adolescents and in women on third-generation oral contraception.

Journal: The Journal of clinical endocrinology and metabolism 20031001

Title: Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor.

Journal: Chemical research in toxicology 20031001

Title: Flutamide-induced hepatic dysfunction in relation to steady-state plasma concentrations of flutamide and its metabolites.

Journal: Molecular and cellular biochemistry 20031001

Title: [From the gene to the clinic: prostate cancer death can now be an exception?].

Journal: Medecine sciences : M/S 20031001

Title: [Comparative study of the effect of complete prolonged neoadjuvant hormonal blockade versus standard hormonal blockade].

Journal: Actas urologicas espanolas 20031001

Title: Neuroendocrine mechanisms of development of experimental hyperandrogen-induced anovulation.

Journal: Neuroscience and behavioral physiology 20031001

Title: Effects of vinclozolin administration on sperm production and testosterone biosynthetic pathway in adult male rat.

Journal: The Journal of reproduction and development 20031001

Title: In vivo preservation of steroid specificity in CWR22 xenografts having a mutated androgen receptor.

Journal: The Prostate 20030915

Title: Intermittent chemotherapy in metastatic androgen-independent prostate cancer.

Journal: British journal of cancer 20030915

Title: Androgen deprivation and cognition in prostate cancer.

Journal: British journal of cancer 20030915

Title: Interleukin-4 enhances prostate-specific antigen expression by activation of the androgen receptor and Akt pathway.

Journal: Oncogene 20030911

Title: Play, copulation, anatomy, and testosterone in gonadally intact male rats prenatally exposed to flutamide.

Journal: Physiology & behavior 20030901

Title: Acceptability of short term neo-adjuvant androgen deprivation in patients with locally advanced prostate cancer.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20030901

Title: [Anemia in patients on combined androgen block therapy for prostate cancer].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20030901

Title: Alteration of lactate production and transport in the adult rat testis exposed in utero to flutamide.

Journal: Molecular and cellular endocrinology 20030829

Title: Anti-androgens with full antagonistic activity toward human prostate tumor LNCaP cells with mutated androgen receptor.

Journal: Bioorganic & medicinal chemistry letters 20030818

Title: Modulation of androgen receptor transactivation by gelsolin: a newly identified androgen receptor coregulator.

Journal: Cancer research 20030815

Title: Prostate specific antigen: a prognostic marker of survival in good prognosis metastatic prostate cancer? (EORTC 30892).

Journal: European urology 20030801

Title: Two organizational effects of pubertal testosterone in male rats: transient social memory and a shift away from long-term potentiation following a tetanus in hippocampal CA1.

Journal: Experimental neurology 20030801

Title: Impact of hormone therapy when combined with external beam radiotherapy for early-stage, intermediate-, or high-risk prostate cancer.

Journal: American journal of clinical oncology 20030801

Title: Pneumonitis and non steroidal antiandrogens.

Journal: Prescrire international 20030801

Title: Effects of perinatal exposure to flutamide on sex hormone responsiveness in F1 male rats.

Journal: The Journal of toxicological sciences 20030801

Title: Comparison of prostate gene expression and tissue weight changes as monitors of antiandrogen activity in GNRH-inhibited rats.

Journal: Birth defects research. Part B, Developmental and reproductive toxicology 20030801

Title: Alterations of gene expression in adult male rat testis and pituitary shortly after subacute administration of the antiandrogen flutamide.

Journal: The Journal of reproduction and development 20030801

Title: Cell-specific and hormone-regulated expression of gonadotropin-regulated testicular RNA helicase gene (GRTH/Ddx25) resulting from alternative utilization of translation initiation codons in the rat testis.

Journal: The Journal of biological chemistry 20030725

Title: Effects of flutamide in the rat testis on the expression of occludin, an integral member of the tight junctions.

Journal: Toxicology letters 20030720

Title: Differential expression of the tetracycline-controlled transactivator-driven human CYP1B1 gene in double-transgenic mice is due to androgens: application for detecting androgens and antiandrogens.

Journal: Archives of biochemistry and biophysics 20030715

Title: UV filters with antagonistic action at androgen receptors in the MDA-kb2 cell transcriptional-activation assay.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030701

Title: Androgen receptor independent cardiovascular action of the antiandrogen flutamide.

Journal: Journal of molecular medicine (Berlin, Germany) 20030701

Title: An environmental antiandrogen, vinclozolin, alters the organization of play behavior.

Journal: Physiology & behavior 20030701

Title: Finasteride and flutamide therapy in patients with advanced prostate cancer: response to subsequent castration and long-term follow-up.

Journal: Urology 20030701

Title: Androgens stimulate hypoxia-inducible factor 1 activation via autocrine loop of tyrosine kinase receptor/phosphatidylinositol 3'-kinase/protein kinase B in prostate cancer cells.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030701

Title: Anti-androgen treatment increases circulating ghrelin levels in obese women with polycystic ovary syndrome.

Journal: Journal of endocrinological investigation 20030701

Title: [Treatment of acne with antiandrogens--an evidence-based review].

Journal: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20030701

Title: Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy.

Journal: Nature medicine 20030601

Title: [Malignant priapism as a sign of a recurrent prostate cancer. Differential diagnosis of induratio penis plastica].

Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20030601

Title: Low-dose flutamide-metformin therapy reverses insulin resistance and reduces fat mass in nonobese adolescents with ovarian hyperandrogenism.

Journal: The Journal of clinical endocrinology and metabolism 20030601

Title: [Therapeutic options for drug induced liver injury: the efficacy of UDCA based on EBM].

Journal: Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20030601

Title: Circulating nitric oxide levels increase after anti-androgen treatment in male-to-female transsexuals.

Journal: Journal of endocrinological investigation 20030601

Title: Ten-year survival in patients with metastatic prostate cancer.

Journal: Clinical prostate cancer 20030601

Title: Quinazoline-based alpha 1-adrenoceptor antagonists induce prostate cancer cell apoptosis via TGF-beta signalling and I kappa B alpha induction.

Journal: British journal of cancer 20030519

Title: The study of spatial memory in adult male rats with injection of testosterone enanthate and flutamide into the basolateral nucleus of the amygdala in Morris water maze.

Journal: Brain research 20030516

Title: Variation in chromogranin A serum levels during intermittent versus continuous androgen deprivation therapy for prostate adenocarcinoma.

Journal: The Prostate 20030515

Title: Effect of the multidrug resistance protein on the transport of the antiandrogen flutamide.

Journal: Cancer research 20030515

Title: Rotational 3D-conformal radiation therapy (conformation therapy) combined with hormone therapy for the treatment of stage B2/C prostate cancer in Japanese men.

Journal: International journal of radiation oncology, biology, physics 20030501

Title: Studies on the interactions between drug and estrogen. II. On the inhibitory effect of 29 drugs reported to induce gynecomastia on the oxidation of estradiol at C-2 or C-17.

Journal: Biological & pharmaceutical bulletin 20030501

Title: The evaluation and management of hirsutism.

Journal: Obstetrics and gynecology 20030501

Title: Anticonvulsant effect of flutamide on seizures induced by pentylenetetrazole: involvement of benzodiazepine receptors.

Journal: Epilepsia 20030501

Title: Endocrine targets in experimental shock.

Journal: The Journal of trauma 20030501

Title: [Neuroendocrine differentiation in adenocarcinoma of the prostate with progression of disease during hormonal treatment: a report of two cases].

Journal: Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20030501

Title: Inhibition of fatty acid synthase expression by 1alpha,25-dihydroxyvitamin D3 in prostate cancer cells.

Journal: The Journal of steroid biochemistry and molecular biology 20030501

Title: Sex differences in interest in infants in juvenile rhesus monkeys: relationship to prenatal androgen.

Journal: Hormones and behavior 20030501

Title: Bioassay of steroid hormone agonist and antagonist activities of anti-androgens on mammary gland, seminal vesicles and spleen of male mice.

Journal: Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20030501

Title: Novel yeast bioassay system for detection of androgenic and antiandrogenic compounds.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20030401

Title: Neoadjuvant flutamide monotherapy for locally confined prostate cancer.

Journal: International journal of urology : official journal of the Japanese Urological Association 20030401

Title: Estradiol alleviates acinar cell apoptosis and chronic pancreatitis in male Wistar Bonn/Kobori rats.

Journal: Pancreas 20030401

Title: Prostate cancer DNA ploidy and response to salvage hormone therapy after radiotherapy with or without short-term total androgen blockade: an analysis of RTOG 8610.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030401

Title: Antiandrogenic activity and metabolism of the organophosphorus pesticide fenthion and related compounds.

Journal: Environmental health perspectives 20030401

Title: Androgen blockade enhances response to melanoma vaccine.

Journal: The Journal of surgical research 20030401

Title: Effects of tributyltin chloride on the reproductive system in pubertal male rats.

Journal: Journal of veterinary science 20030401

Title: Mechanisms of vasorelaxation to testosterone in the rat aorta.

Journal: European journal of pharmacology 20030328

Title: Androgen regulation of parathyroid hormone-related peptide production in human prostate cancer cells.

Journal: Endocrinology 20030301

Title: Effects of androgens on sex differentiation of the urodele Pleurodeles waltl.

Journal: Journal of experimental zoology. Part A, Comparative experimental biology 20030301

Title: Impact of a novel neoadjuvant and adjuvant hormone-deprivation approach on quality of life, voiding function, and sexual function after prostate brachytherapy.

Journal: Cancer 20030301

Title: The role of antiandrogen monotherapy in the treatment of prostate cancer.

Journal: BJU international 20030301

Title: Abolition of end-organ damage by antiandrogen treatment in female hypertensive transgenic rats.

Journal: Hypertension (Dallas, Tex. : 1979) 20030301

Title: Differential regulation of rat testicular 5alpha-reductase type 1 and 2 isoforms by testosterone and FSH.

Journal: The Journal of endocrinology 20030301

Title: Flutamide-induced photosensitivity: is it a forme fruste of lupus?

Journal: The British journal of dermatology 20030301

Title: Microscopic pulmonary tumor embolism secondary to adenocarcinoma of the prostate.

Journal: Hinyokika kiyo. Acta urologica Japonica 20030301

Title: SR31747A is a sigma receptor ligand exhibiting antitumoural activity both in vitro and in vivo.

Journal: British journal of cancer 20030210

Title: The effects of anti-androgenic and estrogenic disrupting contaminants on breeding gland (nuptial pad) morphology, plasma testosterone levels, and plasma vitellogenin levels in male Xenopus laevis (African clawed frog).

Journal: Archives of environmental contamination and toxicology 20030201

Title: Chronic administration of anabolic steroids disrupts pubertal onset and estrous cyclicity in rats.

Journal: Biology of reproduction 20030201

Title: Long-term apoptotic cell death process with increased expression and activation of caspase-3 and -6 in adult rat germ cells exposed in utero to flutamide.

Journal: Endocrinology 20030201

Title: Pem homeobox gene promoter sequences that direct transcription in a Sertoli cell-specific, stage-specific, and androgen-dependent manner in the testis in vivo.

Journal: Molecular endocrinology (Baltimore, Md.) 20030201

Title: Flutamide counteracts the antiproliferative effects of antiprogestins in the primate endometrium.

Journal: The Journal of clinical endocrinology and metabolism 20030201

Title: Collagenous and lymphocytic colitis. evaluation of clinical and histological features, response to treatment, and long-term follow-up.

Journal: The American journal of gastroenterology 20030201

Title: Neoadjuvant androgen deprivation and prostate gland shrinkage during conformal radiotherapy.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20030201

Title: Percentage of the positive area of bone metastasis is an independent predictor of disease death in advanced prostate cancer.

Journal: British journal of cancer 20030127

Title: Metastatic carcinoma of the prostate: identifying prognostic groups using recursive partitioning.

Journal: The Journal of urology 20030101

Title: Race and survival of men treated for prostate cancer on radiation therapy oncology group phase III randomized trials.

Journal: The Journal of urology 20030101

Title: Key structural features of nonsteroidal ligands for binding and activation of the androgen receptor.

Journal: Molecular pharmacology 20030101

Title: Novel mutations of androgen receptor: a possible mechanism of bicalutamide withdrawal syndrome.

Journal: Cancer research 20030101

Title: Regulation of HOXA-10 expression by testosterone in vitro and in the endometrium of patients with polycystic ovary syndrome.

Journal: The Journal of clinical endocrinology and metabolism 20030101

Title: Treatment of hyperandrogenic alopecia in women.

Journal: Fertility and sterility 20030101

Title: Low-dose combination of flutamide, metformin and an oral contraceptive for non-obese, young women with polycystic ovary syndrome.

Journal: Human reproduction (Oxford, England) 20030101

Title: Effects of estrogenic and antiandrogenic compounds on the testis structure of the adult guppy (Poecilia reticulata).

Journal: Ecotoxicology and environmental safety 20030101

Title: [First line therapy in the treatment of metastatic prostate cancer].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20030101

Title: [Expression of androgen receptor protein in hormone refractory prostate cancer].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20030101

Title: Update and future of systemic acne treatment.

Journal: Dermatology (Basel, Switzerland) 20030101

Title: Update and future of hormonal therapy in acne.

Journal: Dermatology (Basel, Switzerland) 20030101

Title: [Antigonadotropic effects of a 19-nor-progesterone derivative: the example of nomegestrol acetate].

Journal: Gynecologie, obstetrique & fertilite 20030101

Title: Prognostic significance of changes in short-term prostate volume and serum prostate-specific antigen after androgen withdrawal in men with metastatic prostate cancer.

Journal: Urologia internationalis 20030101

Title: Flutamide-induced hepatotoxicity with possible potentiation by simvastatin.

Journal: The Journal of the Association of Physicians of India 20030101

Title: Neoadjuvant therapy before radical prostatectomy in high-risk localized prostate cancer: defining appropriate endpoints.

Journal: Urologic oncology 20030101

Title: Combined androgen blockade-induced anemia in prostate cancer patients without bone involvement.

Journal: Anticancer research 20030101

Title: Androgens, estrogens, and mammary epithelial proliferation.

Journal: Menopause (New York, N.Y.) 20030101

Title: A physiologic role for testosterone in limiting estrogenic stimulation of the breast.

Journal: Menopause (New York, N.Y.) 20030101

Title: Androgen receptor in prostate carcinoma: immunohistochemical and ligand saturation analyses.

Journal: Neoplasma 20030101

Title: Hepatic failure with flutamide.

Journal: Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 20030101

Title: Biochemical recurrence of prostate cancer.

Journal: Current problems in cancer 20030101

Title: [The hypothalamic-hypophyseal-gonadal system and its functional reserve during long-term vibration and noise].

Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20030101

Title: Management of epidural cauda equina disease of prostate cancer by radiotherapy.

Journal: Radiation medicine 20030101

Title: Cyproterone acetate for hirsutism.

Journal: The Cochrane database of systematic reviews 20030101

Title: Leptin levels increase during flutamide therapy in women with polycystic ovary syndrome.

Journal: Hormone research 20030101

Title: Flutamide-associated acute liver failure.

Journal: Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna 20030101

Title: Therapeutic androgen receptor ligands.

Journal: Nuclear receptor signaling 20030101

Title: Dietary genistein suppresses chemically induced prostate cancer in Lobund-Wistar rats.

Journal: Cancer letters 20021201

Title: Induction of reproductive tract developmental abnormalities in the male rat by lowering androgen production or action in combination with a low dose of diethylstilbestrol: evidence for importance of the androgen-estrogen balance.

Journal: Endocrinology 20021201

Title: Effect of a short course of neoadjuvant hormonal therapy on the response to subsequent androgen suppression in prostate cancer patients with relapse after radiotherapy: a secondary analysis of the randomized protocol RTOG 86-10.

Journal: International journal of radiation oncology, biology, physics 20021201

Title: Effect of an anti-androgen on testicular descent and inguinal closure in a marsupial, the tammar wallaby (Macropus eugenii).

Journal: Reproduction (Cambridge, England) 20021201

Title: [Antiandrogen in prostate cancer].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20021201

Title: [Total androgen blockade].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20021201

Title: Testosterone suppression in men with prostate cancer is associated with increased arterial stiffness.

Journal: The aging male : the official journal of the International Society for the Study of the Aging Male 20021201

Title: Intermittent versus continuous total androgen blockade in the treatment of patients with advanced hormone-naive prostate cancer: results of a prospective randomized multicenter trial.

Journal: Clinical prostate cancer 20021201

Title: Effects of hydroxyflutamide in the medial preoptic area or lateral septum on reproductive behaviors in male rats.

Journal: Brain research bulletin 20021130

Title: Ligand-dependent aggregation of polyglutamine-expanded androgen receptor in neuronal cells.

Journal: Neuroreport 20021115

Title: Impact of caveolin-1 expression on prognosis of pancreatic ductal adenocarcinoma.

Journal: British journal of cancer 20021104

Title: Effects of prenatal treatment with antiandrogens on luteinizing hormone secretion and sex steroid concentrations in adult spotted hyenas, Crocuta crocuta.

Journal: Biology of reproduction 20021101

Title: Neoadjuvant therapy before radical prostatectomy for clinical T3/T4 carcinoma of the prostate: 5-year followup, Phase II Southwest Oncology Group Study 9109.

Journal: The Journal of urology 20021101

Title: Abolition of hypertension-induced end-organ damage by androgen receptor blockade in transgenic rats harboring the mouse ren-2 gene.

Journal: Journal of the American Society of Nephrology : JASN 20021101

Title: Activation of mitogen-activated protein kinase pathway by the antiandrogen hydroxyflutamide in androgen receptor-negative prostate cancer cells.

Journal: Cancer research 20021101

Title: Bicalutamide monotherapy versus flutamide plus goserelin in prostate cancer: updated results of a multicentric trial.

Journal: European urology 20021101

Title: Sexual dimorphism in the spontaneous recovery from spinal cord injury: a gender gap in beneficial autoimmunity?

Journal: The European journal of neuroscience 20021101

Title: Down-regulation of androgen receptor expression and inhibition of lacrimal gland cell proliferation by retinoic acid.

Journal: Experimental eye research 20021101

Title: Regulation of gonadotropin secretion: implications for polycystic ovary syndrome.

Journal: Seminars in reproductive medicine 20021101

Title: Effects of 17 alpha-methyltestosterone on uterine morphology and heat shock protein expression are mediated through estrogen and androgen receptors.

Journal: The Journal of steroid biochemistry and molecular biology 20021101

Title: Exposure to naturally circulating androgens during foetal life incurs direct reproductive costs in female spotted hyenas, but is prerequisite for male mating.

Journal: Proceedings. Biological sciences 20021007

Title: Sex differences in progesterone receptor expression: a potential mechanism for estradiol-mediated sexual differentiation.

Journal: Endocrinology 20021001

Title: Modulation of the onset of postnatal development of H(+)-ATPase-rich cells by steroid hormones in rat epididymis.

Journal: Biology of reproduction 20021001

Title: Pneumonitis associated with nonsteroidal antiandrogens: presumptive evidence of a class effect.

Journal: Annals of internal medicine 20021001

Title: Flutamide induces relaxation in large and small blood vessels.

Journal: Archives of surgery (Chicago, Ill. : 1960) 20021001

Title: Antiandrogenic effects in vitro and in vivo of the fungicide prochloraz.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20021001

Title: Neoadjuvant hormonal therapy prior to radical prostatectomy: evaluation of pathological downstaging and biochemical relapse.

Journal: Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20021001

Title: Opposite actions of testosterone and progesterone on UCP1 mRNA expression in cultured brown adipocytes.

Journal: Cellular and molecular life sciences : CMLS 20021001

Title: Regulation of the expression of protein kinase C isoenzymes in rat ventral prostate: effects of age, castration and flutamide treatment.

Journal: Life sciences 20020927

Title: Phase II study to evaluate combining gemcitabine with flutamide in advanced pancreatic cancer patients.

Journal: British journal of cancer 20020923

Title: Ovarian hormones after postnatal day 20 reduce neuron number in the rat primary visual cortex.

Journal: Journal of neurobiology 20020915

Title: No androgenic/anti-androgenic effects of bisphenol-A in Hershberger assay using immature castrated rats.

Journal: Toxicology letters 20020905

Title: An evaluation of bicalutamide in the treatment of prostate cancer.

Journal: Expert opinion on pharmacotherapy 20020901

Title: Impact of previous local treatment for prostate cancer on subsequent metastatic disease.

Journal: The Journal of urology 20020901

Title: Pharmacogenomics opportunities in nuclear receptor targeted cancer therapy.

Journal: Current cancer drug targets 20020901

Title: Nerve growth factor induces the re-expression of functional androgen receptors and p75(NGFR) in the androgen-insensitive prostate cancer cell line DU145.

Journal: European journal of endocrinology 20020901

Title: Evaluation of a 15-day screening assay using intact male rats for identifying antiandrogens.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020901

Title: Antiandrogen monotherapy: indications and results.

Journal: Urology 20020901

Title: Androgen receptor as a target in androgen-independent prostate cancer.

Journal: Urology 20020901

Title: In vivo modulation of androgen receptor by androgens.

Journal: Asian journal of andrology 20020901

Title: Effects of testosterone on neuromuscular transmission in rat isolated urinary bladder.

Journal: European journal of pharmacology 20020809

Title: Hormone therapy for locally advanced prostate cancer.

Journal: The Journal of urology 20020801

Title: Involvement of androgen receptor in 17beta-estradiol-induced cell proliferation in rat uterus.

Journal: Biology of reproduction 20020801

Title: A comparison of the relative efficacy of antiandrogens for the treatment of acne in hyperandrogenic women.

Journal: Clinical endocrinology 20020801

Title: Prospective randomised trial comparing diethylstilboestrol and flutamide in the treatment of hormone relapsed prostate cancer.

Journal: International journal of urology : official journal of the Japanese Urological Association 20020801

Title: [Prostatic cancer with multiple pulmonary metastases treated successfully with hormonal therapy: a case report].

Journal: Hinyokika kiyo. Acta urologica Japonica 20020801

Title: Embryonic myosin heavy chain and troponin T isoforms remain in the cremaster muscle of adult rat cryptorchidism induced with flutamide.

Journal: Archives of histology and cytology 20020801

Title: [Sex-difference on flutamide metabolism in rat liver microsomal cytochrome P450 1A2].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20020801

Title: Pure antiandrogens disrupt the recruitment of coactivator GRIP1 to colocalize with androgen receptor in nuclei.

Journal: FEBS letters 20020717

Title: Effects of in utero exposure to the organophosphate insecticide fenitrothion on androgen-dependent reproductive development in the Crl:CD(SD)BR rat.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020701

Title: Hormonal therapies in acne.

Journal: Expert opinion on pharmacotherapy 20020701

Title: Effect of local heating of rat testes after suppression of spermatogenesis by pretreatment with a GnRH agonist and an anti-androgen.

Journal: Reproduction (Cambridge, England) 20020701

Title: Can combined androgen blockade provide long-term control or possible cure of localized prostate cancer?

Journal: Urology 20020701

Title: Flutamide decreases cortisol clearance in patients with congenital adrenal hyperplasia.

Journal: The Journal of clinical endocrinology and metabolism 20020701

Title: Acquisition of agonistic properties of nonsteroidal antiandrogens after treatment with oncostatin M in prostate cancer cells.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020701

Title: Stabilization of androgen receptor protein is induced by agonist, not by antagonists.

Journal: Biochemical and biophysical research communications 20020621

Title: Androgens protect against apolipoprotein E4-induced cognitive deficits.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020615

Title: Changes in bone mineral density, lean body mass and fat content as measured by dual energy x-ray absorptiometry in patients with prostate cancer without apparent bone metastases given androgen deprivation therapy.

Journal: The Journal of urology 20020601

Title: Testosterone and estradiol differentially regulate TSH-induced thyrocyte proliferation in immature and adult rats.

Journal: Steroids 20020601

Title: Decreased 5alpha-dihydrotestosterone catabolism suppresses T lymphocyte functions in males after trauma-hemorrhage.

Journal: American journal of physiology. Cell physiology 20020601

Title: Expression of aquaporin 9 in the adult rat epididymal epithelium is modulated by androgens.

Journal: Biology of reproduction 20020601

Title: Pulmonary vasodilatory action of testosterone: evidence of a calcium antagonistic action.

Journal: Journal of cardiovascular pharmacology 20020601

Title: Additive effects of insulin-sensitizing and anti-androgen treatment in young, nonobese women with hyperinsulinism, hyperandrogenism, dyslipidemia, and anovulation.

Journal: The Journal of clinical endocrinology and metabolism 20020601

Title: The antiandrogenic effect of flutamide improves uterine perfusion in women with polycystic ovary syndrome.

Journal: Fertility and sterility 20020601

Title: Assessing meaningful change in quality of life over time: a users' guide for clinicians.

Journal: Mayo Clinic proceedings 20020601

Title: Cytotoxicity of flutamide and 2-hydroxyflutamide and their effects on CYP1A2 mRNA in primary rat hepatocytes.

Journal: Acta pharmacologica Sinica 20020601

Title: Androgens and environmental antiandrogens affect reproductive development and play behavior in the Sprague-Dawley rat.

Journal: Environmental health perspectives 20020601

Title: Novel non-steroidal/non-anilide type androgen antagonists with an isoxazolone moiety.

Journal: Bioorganic & medicinal chemistry 20020501

Title: A glucocorticoid-responsive mutant androgen receptor exhibits unique ligand specificity: therapeutic implications for androgen-independent prostate cancer.

Journal: Endocrinology 20020501

Title: Evaluation of the 20-day pubertal female assay in Sprague-Dawley rats treated with DES, tamoxifen, testosterone, and flutamide.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020501

Title: AR possesses an intrinsic hormone-independent transcriptional activity.

Journal: Molecular endocrinology (Baltimore, Md.) 20020501

Title: The regulation of HSL and LPL expression by DHT and flutamide in human subcutaneous adipose tissue.

Journal: Diabetes, obesity & metabolism 20020501

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20020501

Title: [Hirsutism and hypertrichosis in adults: investigations and treatment].

Journal: Annales de dermatologie et de venereologie 20020501

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Antiandrogen blocks estrogen-induced masculinization of the song system in female zebra finches.

Journal: Journal of neurobiology 20020401

Title: The amino terminus of the human AR is target for corepressor action and antihormone agonism.

Journal: Molecular endocrinology (Baltimore, Md.) 20020401

Title: Effect of a conserved mutation in uridine diphosphate glucuronosyltransferase 1A1 and 1A6 on glucuronidation of a metabolite of flutamide.

Journal: European journal of clinical pharmacology 20020401

Title: Treatment with flutamide decreases cortisol clearance: implications for therapy in congenital adrenal hyperplasia.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20020401

Title: [The role of bicalutamide in the treatment of prostate cancer].

Journal: Harefuah 20020401

Title: Concept evaluation: androgen-stimulated immature intact male rats as an assay for antiandrogens.

Journal: Regulatory toxicology and pharmacology : RTP 20020401

Title: Stability study of flutamide in solid state and in aqueous solution.

Journal: Drug development and industrial pharmacy 20020401

Title: Novel reagents for the sensitive spectrophotometric determination of flutamide, an anticancer drug in pharmaceutical preparations.

Journal: International journal of pharmaceutics 20020320

Title: Post-hatching hormonal modulation of a sexually dimorphic neuromuscular system controlling song in zebra finches.

Journal: Brain research 20020308

Title: Spermatogenesis, fertility and sexual behavior in a hypospadiac mouse model.

Journal: The Journal of urology 20020301

Title: Exposure of juvenile guppies to three antiandrogens causes demasculinization and a reduced sperm count in adult males.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20020301

Title: Development of two androgen receptor assays using adenoviral transduction of MMTV-luc reporter and/or hAR for endocrine screening.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020301

Title: Anti-androgens for the treatment of hirsutism.

Journal: Expert opinion on investigational drugs 20020301

Title: Toremifene prevents prostate cancer in the transgenic adenocarcinoma of mouse prostate model.

Journal: Cancer research 20020301

Title: Effect of prenatal androgen receptor antagonist or aromatase inhibitor on sexual behavior, partner preference and neuronal Fos responses to estrous female odors in the rat accessory olfactory system.

Journal: Physiology & behavior 20020301

Title: Effects of flutamide on puberty in male rats: an evaluation of the protocol for the assessment of pubertal development and thyroid function.

Journal: Journal of toxicology and environmental health. Part A 20020301

Title: The effect of flutamide and tamoxifen on sex hormone-induced mammary carcinogenesis and pituitary adenoma.

Journal: Breast cancer research and treatment 20020301

Title: Bone alkaline phosphatase serum level predicts the response to antiandrogen withdrawal.

Journal: European urology 20020301

Title: Tibolone and 5alpha-dihydrotestosterone alone or in combination with an antiandrogen in a rat breast tumour model.

Journal: European journal of cancer (Oxford, England : 1990) 20020201

Title: Testosterone-induced vasorelaxation in the rat mesenteric arterial bed is mediated predominantly via potassium channels.

Journal: British journal of pharmacology 20020201

Title: Seasonal differences in the hormonal control of territorial aggression in free-living European stonechats.

Journal: Hormones and behavior 20020201

Title: Parental responsiveness is feminized after neonatal castration in virgin male prairie voles, but is not masculinized by perinatal testosterone in virgin females.

Journal: Hormones and behavior 20020201

Title: Effects of perinatal exposure to flutamide on sex hormones and androgen-dependent organs in F1 male rats.

Journal: The Journal of toxicological sciences 20020201

Title: Low serum testosterone level predicts worse response to endocrine therapy in Japanese patients with metastatic prostate cancer.

Journal: Endocrine journal 20020201

Title: Dehydroepiandrosterone (DHEA) and its sulfated derivative (DHEAS) regulate apoptosis during neurogenesis by triggering the Akt signaling pathway in opposing ways.

Journal: Brain research. Molecular brain research 20020131

Title: Neoadjuvant androgen ablation before radical prostatectomy in cT2bNxMo prostate cancer: 5-year results.

Journal: The Journal of urology 20020101

Title: A role for the androgen receptor in follicular atresia of estrogen receptor beta knockout mouse ovary.

Journal: Biology of reproduction 20020101

Title: Dehydroepiandrosterone inhibits human vascular smooth muscle cell proliferation independent of ARs and ERs.

Journal: The Journal of clinical endocrinology and metabolism 20020101

Title: Endocrine active agents: implications of adverse and non-adverse changes.

Journal: Toxicologic pathology 20020101

Title: Fetal testosterone insufficiency and abnormal proliferation of Leydig cells and gonocytes in rats exposed to di(n-butyl) phthalate.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20020101

Title: Clinical utility of ursodeoxycholic acid in preventing flutamide-induced hepatopathy in patients with prostate cancer: a preliminary study.

Journal: International journal of urology : official journal of the Japanese Urological Association 20020101

Title: Postorgasmic illness syndrome: two cases.

Journal: Journal of sex & marital therapy 20020101

Title: Embryonic development of mouse external genitalia: insights into a unique mode of organogenesis.

Journal: Evolution & development 20020101

Title: Tumour cytochrome P450 and drug activation.

Journal: Current pharmaceutical design 20020101

Title: Acquired neuroendocrine-positivity during maximal androgen blockade in prostate cancer patients.

Journal: Anticancer research 20020101

Title: Flutamide-induced acute renal failure in a patient with metastatic prostate cancer.

Journal: Medical oncology (Northwood, London, England) 20020101

Title: Clinical review: immunodepression in the surgical patient and increased susceptibility to infection.

Journal: Critical care (London, England) 20020101

Title: Acne: effect of hormones on pathogenesis and management.

Journal: American journal of clinical dermatology 20020101

Title: Gender dimorphism in immune responses following trauma and hemorrhage.

Journal: Immunologic research 20020101

Title: Caffeine test in predicting flutamide-induced hepatic injury in patients with prostate cancer.

Journal: Prostate cancer and prostatic diseases 20020101

Title: Hydroxypropyl-beta-cyclodextrin-flutamide inclusion complex. II. Oral and intravenous pharmacokinetics of flutamide in the rat.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20020101

Title: Comparison of the clinical efficacy and safety of flutamide versus flutamide plus an oral contraceptive in the treatment of hirsutism.

Journal: Gynecologic and obstetric investigation 20020101

Title: Hormono-radiotherapy in prostatic carcinoma: prognostic factors and implications for combined modality treatment.

Journal: Tumori 20020101

Title: Parenteral estrogen versus combined androgen deprivation in the treatment of metastatic prostatic cancer -- Scandinavian Prostatic Cancer Group (SPCG) Study No. 5.

Journal: Scandinavian journal of urology and nephrology 20020101

Title: Androgen deprivation in men with prostate cancer is associated with an increased rate of bone loss.

Journal: Prostate cancer and prostatic diseases 20020101

Title: Preliminary toxicity and prostate-specific antigen response of a Phase I/II trial of neoadjuvant hormonal therapy, 103Pd brachytherapy, and three-dimensional conformal external beam irradiation in the treatment of locally advanced prostate cancer.

Journal: Brachytherapy 20020101

Title: Altered gene profiles in fetal rat testes after in utero exposure to di(n-butyl) phthalate.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20011201

Title: Nilutamide: possible utility as a second-line hormonal agent.

Journal: Urology 20011201

Title: Relationship between expression of sex steroid receptors and structure of the seminal vesicles after neonatal treatment of rats with potent or weak estrogens.

Journal: Environmental health perspectives 20011201

Title: [Hepatotoxicity due to flutamide].

Journal: Atencion primaria 20011115

Title: Phase I/II trial evaluating combined radiotherapy and in situ gene therapy with or without hormonal therapy in the treatment of prostate cancer--a preliminary report.

Journal: International journal of radiation oncology, biology, physics 20011101

Title: Tamoxifen is an acute, estrogen-like, coronary vasodilator of porcine coronary arteries in vitro.

Journal: Journal of cardiovascular pharmacology 20011101

Title: Testosterone and prostate specific antigen stimulate generation of reactive oxygen species in prostate cancer cells.

Journal: Carcinogenesis 20011101

Title: Contribution of androgens to chronic allograft nephropathy is mediated by dihydrotestosterone.

Journal: Kidney international 20011101

Title: Regulation of u-PA gene expression in human prostate cancer.

Journal: International journal of cancer 20011101

Title: [A male case of primary bilateral breast cancers during estrogen therapy for prostate cancer].

Journal: Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20011101

Title: Attenuation of vascular endothelial dysfunction by testosterone receptor blockade after trauma and hemorrhagic shock.

Journal: Archives of surgery (Chicago, Ill. : 1960) 20011001

Title: Replacement of surgical castration by GnRH-inhibition or Leydig cell ablation in the male rat Hershberger antiandrogen assay.

Journal: Regulatory toxicology and pharmacology : RTP 20011001

Title: Antiandrogenic pesticides disrupt sexual characteristics in the adult male guppy Poecilia reticulata.

Journal: Environmental health perspectives 20011001

Title: Ketoconazole and Flutamide in the treatment of disseminated intravascular clotting from prostate cancer: a case report and review.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20011001

Title: The antiosteoporotic efficacy of intravenous pamidronate in men with prostate carcinoma receiving combined androgen blockade: a double blind, randomized, placebo-controlled crossover study.

Journal: Cancer 20010915

Title: Use of the probasin promoter ARR2PB to express Bax in androgen receptor-positive prostate cancer cells.

Journal: Journal of the National Cancer Institute 20010905

Title: Differential gene expression in response to methoxychlor and estradiol through ERalpha, ERbeta, and AR in reproductive tissues of female mice.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20010901

Title: Flutamide-induced acute hepatitis in advanced prostate cancer patients.

Journal: International journal of clinical pharmacology and therapeutics 20010901

Title: Testosterone-secreting gonadotropin-responsive adrenal adenoma and its treatment with the antiandrogen flutamide.

Journal: Journal of endocrinological investigation 20010901

Title: [Local staging with magnetic resonance imaging after neoadjuvant hormonal therapy for prostate cancer].

Journal: Hinyokika kiyo. Acta urologica Japonica 20010901

Title: Determination of 2-hydroxyflutamide in human plasma by high-performance liquid chromatography and its application to pharmacokinetic studies.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010805

Title: Androgen-mediated development in male rat offspring exposed to flutamide in utero: permanence and correlation of early postnatal changes in anogenital distance and nipple retention with malformations in androgen-dependent tissues.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20010801

Title: Randomized comparative study of 3 versus 8-month neoadjuvant hormonal therapy before radical prostatectomy: biochemical and pathological effects.

Journal: The Journal of urology 20010801

Title: Prospective evaluation of hot flashes during treatment with parenteral estrogen or complete androgen ablation for metastatic carcinoma of the prostate.

Journal: The Journal of urology 20010801

Title: Regulation of keratinocyte growth factor receptor and androgen receptor in epithelial cells of the human prostate.

Journal: The Journal of urology 20010801

Title: Testosterone suppresses spermatogenesis in juvenile spermatogonial depletion (jsd ) mice.

Journal: Biology of reproduction 20010801

Title: Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate.

Journal: International journal of radiation oncology, biology, physics 20010801

Title: Antiandrogen monotherapy: a new form of treatment for patients with prostate cancer.

Journal: Urology 20010801

Title: Radiation and hormonal therapy for locally advanced and clinically localized prostate cancer.

Journal: Urology 20010801

Title: Androgen-induced up-regulation of tubulin isoforms in neuroblastoma cells.

Journal: Journal of neurochemistry 20010801

Title: The subnuclear three-dimensional image analysis of androgen receptor fused to green fluorescence protein.

Journal: The Journal of biological chemistry 20010727

Title: Kap promoter analysis in vivo: a regulatory role for a truncated L1 repeat.

Journal: Molecular and cellular endocrinology 20010705

Title: Virilization of the urogenital sinus of the tammar wallaby is not unique to 5alpha-androstane-3alpha,17beta-diol.

Journal: Molecular and cellular endocrinology 20010705

Title: Testosterone inhibits spermatogonial differentiation in juvenile spermatogonial depletion mice.

Journal: Endocrinology 20010701

Title: M1 prostate cancer with a serum level of prostate-specific antigen less than 10 ng/mL.

Journal: International journal of urology : official journal of the Japanese Urological Association 20010701

Title: Flutamide-induced hepatotoxicity: report of a case series.

Journal: Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 20010701

Title: Why phase III trials of maximal androgen blockade versus castration in M1 prostate cancer rarely show statistically significant differences.

Journal: The Prostate 20010615

Title: Modulation of gene expression by androgen and oestrogens in the testis and prostate of the adult rat following androgen withdrawal.

Journal: Molecular and cellular endocrinology 20010610

Title: Steroid-sensitive gene-1 is an androgen-regulated gene expressed in prostatic smooth muscle cells in vivo.

Journal: Journal of molecular endocrinology 20010601

Title: Developmental and hormonal regulation of type II DNA topoisomerase in rat testis.

Journal: Journal of molecular endocrinology 20010601

Title: Sex differences in infant rhesus macaque separation-rejection vocalizations and effects of prenatal androgens.

Journal: Hormones and behavior 20010601

Title: Testosterone-mediated neuroprotection through the androgen receptor in human primary neurons.

Journal: Journal of neurochemistry 20010601

Title: Quantification of antiandrogen effect determined by Lightcycler technology.

Journal: Toxicology 20010528

Title: Homology modeling using multiple molecular dynamics simulations and docking studies of the human androgen receptor ligand binding domain bound to testosterone and nonsteroidal ligands.

Journal: Journal of medicinal chemistry 20010524

Title: Initial induction and subsequent reduction of alpha(2u)-globulin in urine and serum of mature male rats after repeated intraperitoneal injections of (anti)estrogen.

Journal: Toxicology 20010511

Title: Dissection and weighing of accessory sex glands after formalin fixation, and a 5-day assay using young mature rats are reliable and feasible in the Hershberger assay.

Journal: Toxicology 20010511

Title: Chemical andropause and amyloid-beta peptide.

Journal: JAMA 20010502

Title: Nongenomic effect of testosterone on chloride secretion in cultured rat efferent duct epithelia.

Journal: American journal of physiology. Cell physiology 20010501

Title: Dexamethasone blocks antioestrogen- and oxidant-induced death of pituitary tumour cells.

Journal: The Journal of endocrinology 20010501

Title: Testosterone receptor blockade restores cellular immunity in male mice after burn injury.

Journal: The Journal of endocrinology 20010501

Title: Effects of acute stanozolol treatment on puberty in female rats.

Journal: Biology of reproduction 20010501

Title: Androgen-driven prostate epithelial cell proliferation and differentiation in vivo involve the regulation of p27.

Journal: Molecular endocrinology (Baltimore, Md.) 20010501

Title: A novel isoform of human fibroblast growth factor 8 is induced by androgens and associated with progression of esophageal carcinoma.

Journal: Digestive diseases and sciences 20010501

Title: [Complete remission of brain metastases from prostate cancer by gamma knife radiosurgery: a case report].

Journal: Hinyokika kiyo. Acta urologica Japonica 20010501

Title: Cross-talk between signal transducer and activator of transcription 3 and androgen receptor signaling in prostate carcinoma cells.

Journal: Biochemical and biophysical research communications 20010427

Title: Appropriate column configurations for the rapid analysis and semipreparative purification of the radiolabeled drug flutamide by high-performance liquid chromatography.

Journal: Journal of chromatography. A 20010420

Title: The effects of intrahippocampal testosterone and flutamide on spatial localization in the Morris water maze.

Journal: Brain research 20010406

Title: Sodium-induced rise in blood pressure is suppressed by androgen receptor blockade.

Journal: American journal of physiology. Heart and circulatory physiology 20010401

Title: Chemoprevention for prostatic carcinoma: The role of flutamide in patients with prostatic intraepithelial neoplasia.

Journal: Urology 20010401

Title: Combined androgen blockade with nonsteroidal antiandrogens for advanced prostate cancer: a systematic review.

Journal: Urology 20010401

Title: [Hirsutism, flutamide and hepatotoxicity].

Journal: Gastroenterologia y hepatologia 20010401

Title: Feasibility and potential gains of enhancing the subacute rat study protocol (OECD test guideline no. 407) by additional parameters selected to determine endocrine modulation. A pre-validation study to determine endocrine-mediated effects of the antiandrogenic drug flutamide.

Journal: Archives of toxicology 20010401

Title: [Predicting long-term survival, and the need for hormonal therapy: a meta-analysis of RTOG prostate cancer trials].

Journal: Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique 20010401

Title: [Clinical efficacy of treatment with low-dose flutamide in maximum androgen blockade therapy].

Journal: Hinyokika kiyo. Acta urologica Japonica 20010401

Title: [What is the role of hormonal treatments in acne?].

Journal: Annales de dermatologie et de venereologie 20010401

Title: [Adenocarcinoma of prostate in men younger than 50--rectal palpation mandatory with micturition problems].

Journal: Nederlands tijdschrift voor geneeskunde 20010324

Title: Administration of tamoxifen but not flutamide to hormonally intact, adult male rats mimics the effects of short-term gonadectomy on the catecholamine innervation of the cerebral cortex.

Journal: The Journal of comparative neurology 20010319

Title: Subset analysis of RTOG 85-31 and 86-10 indicates an advantage for long-term vs. short-term adjuvant hormones for patients with locally advanced nonmetastatic prostate cancer treated with radiation therapy.

Journal: International journal of radiation oncology, biology, physics 20010315

Title: Androgen receptor antagonism by the organophosphate insecticide fenitrothion.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20010301

Title: Testosterone perturbs epidermal permeability barrier homeostasis.

Journal: The Journal of investigative dermatology 20010301

Title: [Long-term survival of hormone-refractory prostate cancer: a case report].

Journal: Journal of UOEH 20010301

Title: The biological effect of phthalate esters on transabdominal migration of the testis in fetal rats in comparison with the antiandrogen flutamide.

Journal: Pediatric surgery international 20010301

Title: Testosterone protects cerebellar granule cells from oxidative stress-induced cell death through a receptor mediated mechanism.

Journal: Brain research 20010223

Title: Testosterone inhibits osteoclast formation stimulated by parathyroid hormone through androgen receptor.

Journal: FEBS letters 20010223

Title: Association of African-American ethnic background with survival in men with metastatic prostate cancer.

Journal: Journal of the National Cancer Institute 20010207

Title: Human CYP1B1 and anticancer agent metabolism: mechanism for tumor-specific drug inactivation?

Journal: The Journal of pharmacology and experimental therapeutics 20010201

Title: [Anemia and neoadjuvant hormone therapy in radical surgery of localized cancer of the prostate].

Journal: Actas urologicas espanolas 20010201

Title: Inhibition of PSA flare in prostate cancer patients by administration of flutamide for 2 weeks before initiation of treatment with slow-releasing LH-RH agonist.

Journal: International journal of clinical oncology 20010201

Title: Sexual dimorphism and aromatase in the rat retina.

Journal: Brain research. Developmental brain research 20010131

Title: Nonsteroidal antiandrogens: a therapeutic option for patients with advanced prostate cancer who wish to retain sexual interest and function.

Journal: BJU international 20010101

Title: Androgen-dependent regulation of human angiotensinogen expression in KAP-hAGT transgenic mice.

Journal: American journal of physiology. Renal physiology 20010101

Title: Flutamide versus prednisone in patients with prostate cancer symptomatically progressing after androgen-ablative therapy: a phase III study of the European organization for research and treatment of cancer genitourinary group.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010101

Title: Mutations at the boundary of the hinge and ligand binding domain of the androgen receptor confer increased transactivation function.

Journal: Molecular endocrinology (Baltimore, Md.) 20010101

Title: Biochemical markers for the detection of bone metastasis in patients with prostate cancer: diagnostic efficacy and the effect of hormonal therapy.

Journal: Journal of bone and mineral metabolism 20010101

Title: Lack of methemoglobinemia with flutamide.

Journal: The Annals of pharmacotherapy 20010101

Title: The photochemistry of flutamide and its inclusion complex with beta-cyclodextrin. Dramatic effect of the microenvironment on the nature and on the efficiency of the photodegradation pathways.

Journal: Photochemistry and photobiology 20010101

Title: An electrochemical evidence of free radicals formation from flutamide and its reactivity with endo/xenobiotics of pharmacological relevance.

Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20010101

Title: Hormonal regulation of appetite and body mass in patients with advanced prostate cancer treated with combined androgen blockade.

Journal: Journal of endocrinological investigation 20010101

Title: Suppression of androgen action and the induction of gross abnormalities of the reproductive tract in male rats treated neonatally with diethylstilbestrol.

Journal: Journal of andrology 20010101

Title: [Suppressive effects of the antiandrogen flutamide on adrenal androgens in advanced prostate cancer patients].

Journal: Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20010101

Title: [Successful complete androgen blockade (CAB) therapy for prostatic cancer detected from multiple lung metastases: a case report].

Journal: Hinyokika kiyo. Acta urologica Japonica 20010101

Title: Treatment of localized prostate cancer with intermittent triple androgen blockade: preliminary results in 110 consecutive patients.

Journal: The oncologist 20010101

Title: Optimal starting time for flutamide to prevent disease flare in prostate cancer patients treated with a gonadotropin-releasing hormone agonist.

Journal: Urologia internationalis 20010101

Title: A risk-benefit assessment of pharmacological therapies for hirsutism.

Journal: Drug safety 20010101

Title: Ultrastructural and quantitative immunohistochemical changes induced by nonsteroid antiandrogens on pituitary gonadotroph population of prepubertal male rats.

Journal: Cells, tissues, organs 20010101

Title: Actions of the endocrine disruptor methoxychlor and its estrogenic metabolite on in vitro embryonic rat seminiferous cord formation and perinatal testis growth.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20010101

Title: Neonatal exposure to potent and environmental oestrogens and abnormalities of the male reproductive system in the rat: evidence for importance of the androgen-oestrogen balance and assessment of the relevance to man.

Journal: Human reproduction update 20010101

Title: Possible androgenic/anti-androgenic activity of the insecticide fenitrothion.

Journal: Journal of applied toxicology : JAT 20010101

Title: Androgen-induced cell growth and c-myc expression in human non-transformed epithelial prostatic cells in primary culture.

Journal: Endocrine research 20010101

Title: Strain sensitivity differences in the Hershberger assay.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20010101

Title: The role of androgens in mammary carcinogenesis.

Journal: Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia 20010101

Title: Testosterone and estradiol have specific differential modulatory effect on the proliferation of human thyroid papillary and follicular carcinoma cell lines independent of TSH action.

Journal: Endocrine pathology 20010101

Title: Structure toxicity relationships--how useful are they in predicting toxicities of new drugs?

Journal: Advances in experimental medicine and biology 20010101

Title: Manipulation of prenatal hormones and dietary phytoestrogens during adulthood alter the sexually dimorphic expression of visual spatial memory.

Journal: BMC neuroscience 20010101

Title: Low-dose flutamide (125 mg/day) as maintenance therapy in the treatment of hirsutism.

Journal: Hormone research 20010101

Title: Conversion of nested reverse-transcriptase polymerase chain reaction from positive to negative status at peripheral blood during androgen ablation therapy is associated with long progression-free survival in stage D2 prostate cancer patients.

Journal: Anticancer research 20010101

Title: [Nucleic acid and protein content in rat prostate during combined treatment with the gonadorelin agonist and an androgen receptor inhibitor].

Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20010101

Title: The effects of GnRH analogues and antiandrogenes in preventing the gonadotoxic effects of COPP chemotherapy.

Journal: International urology and nephrology 20010101

Title: Androgen deprivation and other treatments for advanced prostate cancer.

Journal: Reviews in urology 20010101

Title: New approaches to the treatment of advanced prostate cancer.

Journal: Reviews in urology 20010101

Title: Flare Associated with LHRH-Agonist Therapy.

Journal: Reviews in urology 20010101

Title: Antiandrogenic effects of novel androgen synthesis inhibitors on hormone-dependent prostate cancer.

Journal: Cancer research 20001201

Title: Hormonal and clinical effects of GnRH agonist alone, or in combination with a combined oral contraceptive or flutamide in women with severe hirsutism.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20001201

Title: Antiandrogen withdrawal syndrome associated with prostate cancer therapies: incidence and clinical significance.

Journal: Drug safety 20001101

Title: Effects of in utero exposure to linuron on androgen-dependent reproductive development in the male Crl:CD(SD)BR rat.

Journal: Toxicology and applied pharmacology 20000901

Title: The role of estrogen receptor, androgen receptor and growth factors in diethylstilbestrol-induced programming of prostate differentiation.

Journal: Urological research 20000801

Title: [Fulminant liver failure induced by flutamide].

Journal: Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 20000601

Title: [Toxic hepatitis caused by flutamide and hirsutism].

Journal: Gastroenterologia y hepatologia 20000501

Title: Effects of an environmental anti-androgen on erectile function in an animal penile erection model.

Journal: The Journal of urology 20000401

Title: Evaluation of flutamide genotoxicity in rats and in primary human hepatocytes.

Journal: Pharmacology & toxicology 20000301

Title: Examination of selected food additives and organochlorine food contaminants for androgenic activity in vitro.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20000201

Title: Prostate cancer treated by anti-androgens: is sexual function preserved? EORTC Genitourinary Group. European Organization for Research and Treatment of Cancer.

Journal: British journal of cancer 20000101

Title: Gender differences in hypertension in spontaneously hypertensive rats: role of androgens and androgen receptor.

Journal: Hypertension (Dallas, Tex. : 1979) 19991001

Title: Regulation of GCDFP-15 expression in human mammary cancer cells.

Journal: International journal of molecular medicine 19990801

Title: [Risk factor of liver disorders caused by flutamide--statistical analysis using multivariate logistic regression analysis].

Journal: Hinyokika kiyo. Acta urologica Japonica 19990801

Title: [Primary treatment for stage D2 prostate cancer: a randomized study of combined androgen blockade alone versus combined with UFT].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 19990701

Title: [Fatal hepatic failure following hepatitis caused by flutamide: a case report].

Journal: Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 19990501

Title: [Acute flutamide-induced hepatitis].

Journal: Gastroenterologia y hepatologia 19990501

Title: Fulminant liver failure associated with flutamide therapy for hirsutism.

Journal: Lancet (London, England) 19990320

Title: Frequency of flutamide induced hepatotoxicity in patients with prostate carcinoma.

Journal: Human & experimental toxicology 19990301

Title: Anaemia in men receiving combined finasteride and flutamide therapy for advanced prostate cancer.

Journal: BJU international 19990101

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Journal: Gastroenterologia y hepatologia 19981201

Title: Application of an androgen receptor assay for the characterisation of the androgenic or antiandrogenic activity of various phenylurea herbicides and their derivatives.

Journal: The Analyst 19981201

Title: [Ischemic colitis after taking flutamide].

Journal: Gastroenterologie clinique et biologique 19981001

Title: Several environmental oestrogens are also anti-androgens.

Journal: The Journal of endocrinology 19980901

Title: Inhibition of androgen receptor-dependent transcriptional activity by DDT isomers and methoxychlor in HepG2 human hepatoma cells.

Journal: Toxicology and applied pharmacology 19980701

Title: Flutamide-induced acute hepatitis: investigation on the role of immunoallergic mechanisms.

Journal: Italian journal of gastroenterology and hepatology 19980601

Title: [Acute cholestatic hepatitis secondary to flutamide].

Journal: Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 19980501

Title: [The hepatotoxicity of flutamide].

Journal: Klinicheskaia meditsina 19980101

Title: [A case of fulminant hepatitis caused by antiandrogen, flutamide in a patient with prostate cancer].

Journal: Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 19970701

Title: Comparison of in vitro effects of the pure antiandrogens OH-flutamide, Casodex, and nilutamide on androgen-sensitive parameters.

Journal: Urology 19970401

Title: Evaluation of chemicals with endocrine modulating activity in a yeast-based steroid hormone receptor gene transcription assay.

Journal: Toxicology and applied pharmacology 19970301

Title: [Liver failure caused by flutamide].

Journal: Actas urologicas espanolas 19970301

Title: [Fulminant liver failure with a fatal outcome due to flutamide].

Journal: Medicina clinica 19970215

Title: Vinclozolin and p,p'-DDE alter androgen-dependent gene expression: in vivo confirmation of an androgen receptor-mediated mechanism.

Journal: Toxicology and applied pharmacology 19970101

Title: Non-steroidal L-245,976 acts as a classical antiandrogen in vitro.

Journal: The Journal of steroid biochemistry and molecular biology 19970101

Title: Flutamide-induced toxic hepatitis. Potential utility of ursodeoxycholic acid administration in toxic hepatitis.

Journal: Digestive diseases and sciences 19961101

Title: Double-blind, randomized study of primary hormonal treatment of stage D2 prostate carcinoma: flutamide versus diethylstilbestrol.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19960801

Title: A case of flutamide-induced acute cholestatic hepatitis--a case report.

Journal: Yonsei medical journal 19960601

Title: [Fulminant hepatitis caused by flutamide].

Journal: Gastroenterologie clinique et biologique 19960201

Title: [Hepatic encephalopathy induced by flutamide administered for the treatment of prostatic cancer].

Journal: Journal d'urologie 19960101

Title: [Effects of androgen regulation system on bladder carcinogenesis in male mice].

Journal: Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 19951101

Title: Hepatic insufficiency developing as a result of flutamide treatment.

Journal: The American journal of gastroenterology 19950601

Title: Use of flutamide for self-induced androgen excess. A case report.

Journal: The Journal of reproductive medicine 19941001

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Journal: Journal of hepatology 19940301

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Journal: Digestive diseases and sciences 19930901

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Journal: European urology 19930101

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Tags:13311-84-7 Molecular Formula|13311-84-7 MDL|13311-84-7 SMILES|13311-84-7 2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide