Home Other Building Blocks 1346527-98-7
1346527-98-7,MFCD28137687
Catalog No.:AA009CKG

1346527-98-7 | Ml240

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98+%
in stock  
$14.00   $10.00
- +
5mg
98+%
in stock  
$34.00   $24.00
- +
10mg
98+%
in stock  
$51.00   $36.00
- +
25mg
98+%
in stock  
$84.00   $59.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA009CKG
Chemical Name:
Ml240
CAS Number:
1346527-98-7
Molecular Formula:
C23H20N6O
Molecular Weight:
396.4445
MDL Number:
MFCD28137687
SMILES:
COc1cccc2c1nc(nc2NCc1ccccc1)n1c(N)nc2c1cccc2
Properties
Computed Properties
 
Complexity:
558  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
5  
XLogP3:
4.5  

Downstream Synthesis Route

[1]Zhou,Han-Jie;Wang,Jinhai;Yao,Bing;Wong,Steve;Djakovic,Stevan;Kumar,Brajesh;Rice,Julie;Valle,Eduardo;Soriano,Ferdie;Menon,Mary-Kamala;Madriaga,Antonett;KissVonSoly,Szerenke;Kumar,Abhinav;Parlati,Francesco;Yakes,F.Michael;Shawver,Laura;LeMoigne,Ronan;Anderson,DanielJ.;Rolfe,Mark;Wustrow,David[JournalofMedicinalChemistry,2015,vol.58,#24,p.9480-9497]

[1]Zhou,Han-Jie;Wang,Jinhai;Yao,Bing;Wong,Steve;Djakovic,Stevan;Kumar,Brajesh;Rice,Julie;Valle,Eduardo;Soriano,Ferdie;Menon,Mary-Kamala;Madriaga,Antonett;KissVonSoly,Szerenke;Kumar,Abhinav;Parlati,Francesco;Yakes,F.Michael;Shawver,Laura;LeMoigne,Ronan;Anderson,DanielJ.;Rolfe,Mark;Wustrow,David[JournalofMedicinalChemistry,2015,vol.58,#24,p.9480-9497]

Literature

Title: Chou TF et al. Structure-activity relationship study reveals ML240 and ML241 as potent and selective inhibitors of p97 ATPase. ChemMedChem, 2013 Feb, 8(2):297-312.

Title: Chou TF, et al. Selective, reversible inhibitors of the AAA ATPase p97. Probe Reports from the NIH Molecular Libraries Program. April 14, 2011.

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