Title: The wakefulness promoting drug Modafinil causes adenosine receptor-mediated upregulation of receptor activator of nuclear factor κB ligand in osteoblasts: Negative impact of the drug on peak bone accrual in rats.
Journal: Toxicology and applied pharmacology 20180601
Title: Imidacloprid, a neonicotinoid insecticide, facilitates tyrosine hydroxylase transcription and phenylethanolamine N-methyltransferase mRNA expression to enhance catecholamine synthesis and its nicotine-evoked elevation in PC12D cells.
Journal: Toxicology 20180201
Title: Equilibrative nucleoside transporter ENT1 as a biomarker of Huntington disease.
Journal: Neurobiology of disease 20161201
Title: Cordycepin induces apoptosis of C6 glioma cells through the adenosine 2A receptor-p53-caspase-7-PARP pathway.
Journal: Chemico-biological interactions 20140605
Title: Adenosine A2A receptor as a drug discovery target.
Journal: Journal of medicinal chemistry 20140508
Title: Resveratrol mediates anti-atherogenic effects on cholesterol flux in human macrophages and endothelium via PPARγ and adenosine.
Journal: European journal of pharmacology 20130105
Title: Adenosine A2A receptor modulates vascular response in soluble epoxide hydrolase-null mice through CYP-epoxygenases and PPARγ.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20130101
Title: A novel dihydro-pyrazolo(3,4d)(1,2,4)triazolo(1,5a)pyrimidin-4-one (AJ23) is an antagonist at adenosine A(1) receptors and enhances consolidation of step-down avoidance.
Journal: Behavioural brain research 20121001
Title: Pharmacological blockade of adenosine A2A receptors diminishes scarring.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20121001
Title: The mechanism of beta-adrenergic preconditioning: roles for adenosine and ROS during triggering and mediation.
Journal: Basic research in cardiology 20120901
Title: mGlu5 and adenosine A2A receptor interactions regulate the conditioned effects of cocaine.
Journal: The international journal of neuropsychopharmacology 20120801
Title: The effect of adenosine A(2A) receptor antagonists on hydroxyl radical, dopamine, and glutamate in the striatum of rats with altered function of VMAT2.
Journal: Neurotoxicity research 20120801
Title: Structural basis for allosteric regulation of GPCRs by sodium ions.
Journal: Science (New York, N.Y.) 20120713
Title: Suppression of bladder overactivity by adenosine A2A receptor antagonist in a rat model of Parkinson disease.
Journal: The Journal of urology 20120501
Title: The effect of A(2A) adenosine receptor activation on C-C chemokine receptor 7 expression in human THP1 macrophages during inflammation.
Journal: Inflammation 20120401
Title: Effect of adenosine A2A receptor antagonist ZM241385 on amygdala-kindled seizures and progression of amygdala kindling.
Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20120401
Title: Cannabidiol, a non-psychotropic plant-derived cannabinoid, decreases inflammation in a murine model of acute lung injury: role for the adenosine A(2A) receptor.
Journal: European journal of pharmacology 20120305
Title: Effect of adenosine A(2A) receptor antagonists and L-DOPA on hydroxyl radical, glutamate and dopamine in the striatum of 6-OHDA-treated rats.
Journal: Neurotoxicity research 20120201
Title: Functional interaction between purinergic receptors: effect of ligands for A2A and P2Y12 receptors on P2Y1 receptor function.
Journal: FEBS letters 20111215
Title: Adenosine reduces cell surface expression of toll-like receptor 4 and inflammation in response to lipopolysaccharide and matrix products.
Journal: Journal of cardiovascular translational research 20111201
Title: Computational study of the binding modes of caffeine to the adenosine A2A receptor.
Journal: The journal of physical chemistry. B 20111201
Title: Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine.
Journal: Structure (London, England : 1993) 20110907
Title: Adenosine A(2A) receptor activation prevents progressive kidney fibrosis in a model of immune-associated chronic inflammation.
Journal: Kidney international 20110801
Title: New 2-heterocyclyl-imidazo[2,1-i]purin-5-one derivatives as potent and selective human A3 adenosine receptor antagonists.
Journal: Journal of medicinal chemistry 20110728
Title: Biophysical mapping of the adenosine A2A receptor.
Journal: Journal of medicinal chemistry 20110714
Title: Adenosine A2(A) receptor modulates the oxidative stress response of primed polymorphonuclear leukocytes after parabolic flight.
Journal: Human immunology 20110701
Title: Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation.
Journal: Nature 20110518
Title: Structural features of adenosine receptors: from crystal to function.
Journal: Biochimica et biophysica acta 20110501
Title: Structure of an agonist-bound human A2A adenosine receptor.
Journal: Science (New York, N.Y.) 20110415
Title: Abnormal calcium handling in atrial fibrillation is linked to up-regulation of adenosine A2A receptors.
Journal: European heart journal 20110301
Title: Discovery of phosphoric acid mono-{2-[(E/Z)-4-(3,3-dimethyl-butyrylamino)-3,5-difluoro-benzoylimino]-thiazol-3-ylmethyl} ester (Lu AA47070): a phosphonooxymethylene prodrug of a potent and selective hA(2A) receptor antagonist.
Journal: Journal of medicinal chemistry 20110210
Title: Synthesis and biological evaluation of a new series of 1,2,4-triazolo[1,5-a]-1,3,5-triazines as human A(2A) adenosine receptor antagonists with improved water solubility.
Journal: Journal of medicinal chemistry 20110210
Title: GPCR structure and activation: an essential role for the first extracellular loop in activating the adenosine A2B receptor.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110201
Title: Pyrimidine derivatives as potent and selective A3 adenosine receptor antagonists.
Journal: Journal of medicinal chemistry 20110127
Title: Differential recruitment of high affinity A1 and A2A adenosine receptors in the control of colonic neuromuscular function in experimental colitis.
Journal: European journal of pharmacology 20110115
Title: Involvement of adenosine signaling in controlling the release of ghrelin from the mouse stomach.
Journal: The Journal of pharmacology and experimental therapeutics 20110101
Title: A(2A) adenosine receptor binding parameters in platelets from patients affected by pathological gambling.
Journal: Neuropsychobiology 20110101
Title: Adenosine receptor regulation of coronary blood flow in Ossabaw miniature swine.
Journal: The Journal of pharmacology and experimental therapeutics 20101201
Title: Peripheral adenosine A2A receptors are involved in carrageenan-induced mechanical hyperalgesia in mice.
Journal: Neuroscience 20101027
Title: Cooperative cardioprotection through adenosine A1 and A2A receptor agonism in ischemia-reperfused isolated mouse heart.
Journal: Journal of cardiovascular pharmacology 20101001
Title: Inosine reduces pain-related behavior in mice: involvement of adenosine A1 and A2A receptor subtypes and protein kinase C pathways.
Journal: The Journal of pharmacology and experimental therapeutics 20100801
Title: Adenosine A(2) receptors modulate tubuloglomerular feedback.
Journal: American journal of physiology. Renal physiology 20100801
Title: Adenosine A(2)A receptor but not HIF-1 mediates Tyrosine hydroxylase induction in hypoxic PC12 cells.
Journal: Journal of neuroscience research 20100701
Title: Lipopolysaccharide and TNF-alpha modify adenosine A(2A) receptor expression and function in equine monocytes.
Journal: Veterinary immunology and immunopathology 20100615
Title: Priming of signal transducer and activator of transcription proteins for cytokine-triggered polyubiquitylation and degradation by the A 2A adenosine receptor.
Journal: Molecular pharmacology 20100601
Title: Activation of adenosine A2A receptor attenuates inflammatory response in a rat model of small-for-size liver transplantation.
Journal: Transplantation proceedings 20100601
Title: Acadesine inhibits tissue factor induction and thrombus formation by activating the phosphoinositide 3-kinase/Akt signaling pathway.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20100501
Title: Adenosine activates a2b receptors and enhances chloride secretion in kidney inner medullary collecting duct cells.
Journal: Hypertension (Dallas, Tex. : 1979) 20100501
Title: Ligand binding and subtype selectivity of the human A(2A) adenosine receptor: identification and characterization of essential amino acid residues.
Journal: The Journal of biological chemistry 20100423
Title: Role of adenosine A2 receptors in regulation of cerebral blood flow during induced hypotension.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20100401
Title: Predicted 3D structures for adenosine receptors bound to ligands: comparison to the crystal structure.
Journal: Journal of structural biology 20100401
Title: Adenosine inhibits paraventricular pre-sympathetic neurons through ATP-dependent potassium channels.
Journal: Journal of neurochemistry 20100401
Title: Synthesis of theophylline derivatives and study of their activity as antagonists at adenosine receptors.
Journal: Bioorganic & medicinal chemistry 20100315
Title: DNA methylation regulates adenosine A(2A) receptor cell surface expression levels.
Journal: Journal of neurochemistry 20100301
Title: The role of adenosine receptors in regulating production of tumour necrosis factor-alpha and chemokines by human lung macrophages.
Journal: British journal of pharmacology 20100301
Title: Blockade of adenosine A2A receptor counteracts neuropeptide-S-induced hyperlocomotion in mice.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20100201
Title: Static magnetic field exposure reproduces cellular effects of the Parkinson's disease drug candidate ZM241385.
Journal: PloS one 20100101
Title: 2-Phenylpyrazolo[4,3-d]pyrimidin-7-one as a new scaffold to obtain potent and selective human A3 adenosine receptor antagonists: new insights into the receptor-antagonist recognition.
Journal: Journal of medicinal chemistry 20091210
Title: Inhibition of the adenosine2A receptor-epoxyeicosatrienoic acid pathway renders Dahl salt-resistant rats hypertensive.
Journal: Hypertension (Dallas, Tex. : 1979) 20091201
Title: Human follicular lymphoma CD39+-infiltrating T cells contribute to adenosine-mediated T cell hyporesponsiveness.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20091115
Title: Homology modelling of the human adenosine A2B receptor based on X-ray structures of bovine rhodopsin, the beta2-adrenergic receptor and the human adenosine A2A receptor.
Journal: Journal of computer-aided molecular design 20091101
Title: Differential regulation of HIF-1alpha isoforms in murine macrophages by TLR4 and adenosine A(2A) receptor agonists.
Journal: Journal of leukocyte biology 20090901
Title: Cannabidiol ameliorates cognitive and motor impairments in mice with bile duct ligation.
Journal: Journal of hepatology 20090901
Title: Region-specific neuroprotective effect of ZM 241385 towards glutamate uptake inhibition in cultured neurons.
Journal: European journal of pharmacology 20090901
Title: Adenosine A2A receptors enable the synaptic effects of cannabinoid CB1 receptors in the rodent striatum.
Journal: Journal of neurochemistry 20090901
Title: Angiotensin II enhances the afferent arteriolar response to adenosine through increases in cytosolic calcium.
Journal: Acta physiologica (Oxford, England) 20090801
Title: Role of ATP and related purines in inhibitory neurotransmission to the pig urinary bladder neck.
Journal: British journal of pharmacology 20090801
Title: Adenosine A1 receptors presynaptically modulate excitatory synaptic input onto subiculum neurons.
Journal: Brain research 20090714
Title: The adenosine A2A receptor antagonist ZM241385 enhances neuronal survival after oxygen-glucose deprivation in rat CA1 hippocampal slices.
Journal: British journal of pharmacology 20090701
Title: Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008.
Journal: Nature reviews. Drug discovery 20090601
Title: Synthesis of a series of 8-(substituted-phenyl)xanthines and a study on the effects of substitution pattern of phenyl substituents on affinity for adenosine A(1) and A(2A) receptors.
Journal: European journal of medicinal chemistry 20090501
Title: Regulation of somatostatin release by adenosine in the mouse stomach.
Journal: The Journal of pharmacology and experimental therapeutics 20090501
Title: Multiple receptor subtypes and multiple mechanisms of dilation are involved in vascular network dilation caused by adenosine.
Journal: Microvascular research 20090501
Title: Cardioprotection induced by adenosine A1 receptor agonists in a cardiac cell ischemia model involves cooperative activation of adenosine A2A and A2B receptors by endogenous adenosine.
Journal: Journal of cardiovascular pharmacology 20090501
Title: A2A adenosine receptor antagonists protect the striatum against rotenone-induced neurotoxicity.
Journal: Experimental neurology 20090501
Title: Activation of NTS A2a adenosine receptors differentially resets baroreflex control of renal vs. adrenal sympathetic nerve activity.
Journal: American journal of physiology. Heart and circulatory physiology 20090401
Title: Nitric oxide (NO) does not contribute to the generation or action of adenosine during exercise hyperaemia in rat hindlimb.
Journal: The Journal of physiology 20090401
Title: Elucidation in the rat of the role of adenosine and A2A-receptors in the hyperaemia of twitch and tetanic contractions.
Journal: The Journal of physiology 20090401
Title: Adenosine A1 and A2a receptors modulate insulinemia, glycemia, and lactatemia in fetal sheep.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090301
Title: Adenosine receptor antagonists improve short-term object-recognition ability of spontaneously hypertensive rats: a rodent model of attention-deficit hyperactivity disorder.
Journal: Behavioural pharmacology 20090301
Title: The role of adenosine A(1) receptors in mediating the inhibitory effects of low frequency stimulation of perforant path on kindling acquisition in rats.
Journal: Neuroscience 20090218
Title: Modulation of gamma oscillations by endogenous adenosine through A1 and A2A receptors in the mouse hippocampus.
Journal: Neuropharmacology 20090201
Title: Caffeine modulates TNF-alpha production by cord blood monocytes: the role of adenosine receptors.
Journal: Pediatric research 20090201
Title: Effect of adenosine A(2A) receptor antagonists on L-DOPA-induced hydroxyl radical formation in rat striatum.
Journal: Neurotoxicity research 20090201
Title: Adenosine A(1) and A(2A) receptors in mouse prefrontal cortex modulate acetylcholine release and behavioral arousal.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090121
Title: Attenuation of gastric mucosal inflammation induced by indomethacin through activation of the A2A adenosine receptor in rats.
Journal: Journal of gastroenterology 20090101
Title: Alcohol-induced retrograde memory impairment in rats: prevention by caffeine.
Journal: Psychopharmacology 20081201
Title: FGF acts as a co-transmitter through adenosine A(2A) receptor to regulate synaptic plasticity.
Journal: Nature neuroscience 20081201
Title: Atheroprotective effects of methotrexate on reverse cholesterol transport proteins and foam cell transformation in human THP-1 monocyte/macrophages.
Journal: Arthritis and rheumatism 20081201
Title: The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist.
Journal: Science (New York, N.Y.) 20081121
Title: Cerebral blood flow response in adenosine 2a receptor knockout mice during transient hypoxic hypoxia.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20081001
Title: Neonatal caffeine induces sex-specific developmental plasticity of the hypoxic respiratory chemoreflex in adult rats.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20080901
Title: Adenosine receptor subtypes in the airways responses to 5'-adenosine monophosphate inhalation of sensitized guinea-pigs.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20080901
Title: Human equilibrative nucleoside transporters 1 and 2 may be differentially modulated by A2B adenosine receptors in placenta microvascular endothelial cells from pre-eclampsia.
Journal: Placenta 20080901
Title: 2-Amino-6-furan-2-yl-4-substituted nicotinonitriles as A2A adenosine receptor antagonists.
Journal: Journal of medicinal chemistry 20080814
Title: Pharmacological blockade of A2A receptors prevents dermal fibrosis in a model of elevated tissue adenosine.
Journal: The American journal of pathology 20080601
Title: Involvement of the adenosine A1 and A2A receptors in the antidepressant-like effect of zinc in the forced swimming test.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20080515
Title: Hypotensive effects of intravenously administered uridine and cytidine in conscious rats: involvement of adenosine receptors.
Journal: European journal of pharmacology 20080414
Title: Up-regulation of adenosine receptors in the frontal cortex in Alzheimer's disease.
Journal: Brain pathology (Zurich, Switzerland) 20080401
Title: Stimulation of adenosine A2A receptor inhibits LPS-induced expression of intercellular adhesion molecule 1 and production of TNF-alpha in human peripheral blood mononuclear cells.
Journal: Shock (Augusta, Ga.) 20080201
Title: Adenosine A2A receptor agonists inhibit lipopolysaccharide-induced production of tumor necrosis factor-alpha by equine monocytes.
Journal: Veterinary immunology and immunopathology 20080115
Title: Adenosine A(2A) receptors are required for normal BDNF levels and BDNF-induced potentiation of synaptic transmission in the mouse hippocampus.
Journal: Journal of neurochemistry 20080101
Title: Activation of adenosine 2A receptors preserves structure and function of podocytes.
Journal: Journal of the American Society of Nephrology : JASN 20080101
Title: Critical role of hypoxia and A2A adenosine receptors in liver tissue-protecting physiological anti-inflammatory pathway.
Journal: Molecular medicine (Cambridge, Mass.) 20080101
Title: Interaction of A2A adenosine and D2 dopamine receptors modulates corticostriatal glutamatergic transmission.
Journal: Neuropharmacology 20071101
Title: Purinergic modulation of glutamate release under ischemic-like conditions in the hippocampus.
Journal: Neuroscience 20071012
Title: Targeted deletion of A2A adenosine receptors attenuates the protective effects of myocardial postconditioning.
Journal: American journal of physiology. Heart and circulatory physiology 20071001
Title: The role of adenosine A1 and A2A receptors of entorhinal cortex on piriform cortex kindled seizures in rats.
Journal: Pharmacological research 20070801
Title: Blockade of adenosine A(2A) receptors prevents staurosporine-induced apoptosis of rat hippocampal neurons.
Journal: Neurobiology of disease 20070801
Title: Endogenous expression of adenosine A1, A2 and A3 receptors in rat C6 glioma cells.
Journal: Neurochemical research 20070601
Title: Adenosine closes the K+ channel KCa3.1 in human lung mast cells and inhibits their migration via the adenosine A2A receptor.
Journal: European journal of immunology 20070601
Title: Effects of stimulation of adenosine A2A receptors on lipopolysaccharide-induced production of reactive oxygen species by equine neutrophils.
Journal: American journal of veterinary research 20070601
Title: Anticonvulsant effect of A1 but not A2A adenosine receptors of piriform cortex in amygdala-kindled rats.
Journal: Canadian journal of physiology and pharmacology 20070601
Title: Increase in A2A receptors in the nucleus accumbens after extended cocaine self-administration and its disappearance after cocaine withdrawal.
Journal: Brain research 20070427
Title: Disruption of adenosinergic modulation of ventilation at rest and during hypercapnia by neonatal caffeine in young rats: role of adenosine A(1) and A(2A) receptors.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20070401
Title: Interleukin-1beta but not tumor necrosis factor-alpha potentiates neuronal damage by quinolinic acid: protection by an adenosine A2A receptor antagonist.
Journal: Journal of neuroscience research 20070401
Title: Activation of adenosine 2A receptors attenuates allograft rejection and alloantigen recognition.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20070401
Title: Attenuation of reperfusion lung injury and apoptosis by A2A adenosine receptor activation is associated with modulation of Bcl-2 and Bax expression and activation of extracellular signal-regulated kinases.
Journal: Shock (Augusta, Ga.) 20070301
Title: Cell death in rat cerebellar granule neurons induced by hydrogen peroxide in vitro: mechanisms and protection by adenosine receptor ligands.
Journal: Brain research 20070209
Title: Stimulation of adenosine A1 and A2A receptors by AMP in the submucosal plexus of guinea pig small intestine.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20070201
Title: Tonic adenosine A1 and A2A receptor activation is required for the excitatory action of VIP on synaptic transmission in the CA1 area of the hippocampus.
Journal: Neuropharmacology 20070201
Title: ZM241385, DPCPX, MRS1706 are inverse agonists with different relative intrinsic efficacies on constitutively active mutants of the human adenosine A2B receptor.
Journal: The Journal of pharmacology and experimental therapeutics 20070201
Title: A novel mechanism of vasoregulation: ADP-induced relaxation of the porcine isolated coronary artery is mediated via adenosine release.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070201
Title: The A2a/A2b receptor antagonist ZM-241385 blocks the cardioprotective effect of adenosine agonist pretreatment in in vivo rat myocardium.
Journal: American journal of physiology. Heart and circulatory physiology 20070101
Title: Adenosine A2A receptor modulation of juvenile female rat skeletal muscle microvessel permeability.
Journal: American journal of physiology. Heart and circulatory physiology 20061201
Title: Cl-IB-MECA [2-chloro-N6-(3-iodobenzyl)adenosine-5'-N-methylcarboxamide] reduces ischemia/reperfusion injury in mice by activating the A3 adenosine receptor.
Journal: The Journal of pharmacology and experimental therapeutics 20061201
Title: Deficits of glutamate transmission in the striatum of experimental hemiballism.
Journal: Neuroscience 20061117
Title: Adenosine receptors located in the NTS contribute to renal sympathoinhibition during hypotensive phase of severe hemorrhage in anesthetized rats.
Journal: American journal of physiology. Heart and circulatory physiology 20061101
Title: Expression of adenosine receptors in cardiac fibroblasts as a function of insulin and glucose level.
Journal: Archives of biochemistry and biophysics 20061101
Title: Corpus cavernosum from men with vasculogenic impotence is partially resistant to adenosine relaxation due to endothelial A(2B) receptor dysfunction.
Journal: The Journal of pharmacology and experimental therapeutics 20061001
Title: Mouse spinal cord compression injury is reduced by either activation of the adenosine A2A receptor on bone marrow-derived cells or deletion of the A2A receptor on non-bone marrow-derived cells.
Journal: Neuroscience 20060915
Title: Contribution of adenosine A2A and A2B receptors and heme oxygenase to AMPA-induced dilation of pial arterioles in rats.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20060901
Title: Role of adenosine A1 receptors in the modulation of dopamine D1 and adenosine A2A receptor signaling in the neostriatum.
Journal: Neuroscience 20060811
Title: Adenosine A(2A) receptors play a role in the pathogenesis of hepatic cirrhosis.
Journal: British journal of pharmacology 20060801
Title: Contribution of adenosine receptors in the control of arteriolar tone and adenosine-angiotensin II interaction.
Journal: Kidney international 20060801
Title: Adenosine A2A receptors in diffuse dermal fibrosis: pathogenic role in human dermal fibroblasts and in a murine model of scleroderma.
Journal: Arthritis and rheumatism 20060801
Title: Functional and cytoarchitectural spinal cord protection by ATL-146e after ischemia/reperfusion is mediated by adenosine receptor agonism.
Journal: Journal of vascular surgery 20060801
Title: Both endothelium and afferent nerve endings play a role in acetylcholine-induced renal vasodilation.
Journal: Life sciences 20060724
Title: Early and transient alteration of adenosine A2A receptor signaling in a mouse model of Huntington disease.
Journal: Neurobiology of disease 20060701
Title: Adenosine A2A receptor stimulation decreases GAT-1-mediated GABA uptake in the globus pallidus of the rat.
Journal: Neuropharmacology 20060701
Title: Caffeine inhibition of rat carotid body chemoreceptors is mediated by A2A and A2B adenosine receptors.
Journal: Journal of neurochemistry 20060701
Title: Characterization of [125I]ZM 241385 binding to adenosine A2A receptors in the pineal of sheep brain.
Journal: Brain research 20060622
Title: Adenosine as an active component of Antrodia cinnamomea that prevents rat PC12 cells from serum deprivation-induced apoptosis through the activation of adenosine A(2A) receptors.
Journal: Life sciences 20060613
Title: Adenosine A2A receptors promote adenosine-stimulated wound healing in bronchial epithelial cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20060501
Title: Adenosine A2A receptor inactivation increases survival in polymicrobial sepsis.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20060501
Title: Neurogenic secretion mediated by the purinergic P2Y1 receptor in guinea-pig small intestine.
Journal: European journal of pharmacology 20060424
Title: Complement activation-related cardiac anaphylaxis in pigs: role of C5a anaphylatoxin and adenosine in liposome-induced abnormalities in ECG and heart function.
Journal: American journal of physiology. Heart and circulatory physiology 20060301
Title: Adenosine receptors as therapeutic targets.
Journal: Nature reviews. Drug discovery 20060301
Title: Dialysis delivery of an adenosine A2A agonist into the pontine reticular formation of C57BL/6J mouse increases pontine acetylcholine release and sleep.
Journal: Journal of neurochemistry 20060301
Title: Tachycardia caused by A2A adenosine receptor agonists is mediated by direct sympathoexcitation in awake rats.
Journal: The Journal of pharmacology and experimental therapeutics 20060201
Title: A2a receptors mediate inhibitory effects of adenosine on colonic motility in the presence of experimental colitis.
Journal: Inflammatory bowel diseases 20060201
Title: Adenosine concentration in the porcine coronary artery wall and A2A receptor involvement in hypoxia-induced vasodilatation.
Journal: The Journal of physiology 20060115
Title: Contractile effects of adenosine A1 and A2A receptors in isolated murine hearts.
Journal: American journal of physiology. Heart and circulatory physiology 20060101
Title: The cellular mechanisms by which adenosine evokes release of nitric oxide from rat aortic endothelium.
Journal: The Journal of physiology 20060101
Title: Adenosine A1 and A2A receptors of hippocampal CA1 region have opposite effects on piriform cortex kindled seizures in rats.
Journal: Seizure 20060101
Title: Effects of the A 2A adenosine receptor antagonist KW6002 in the nucleus accumbens in vitro and in vivo.
Journal: Pharmacology, biochemistry, and behavior 20060101
Title: The role of adenosine A2a receptors in experimental acute pancreatitis.
Journal: Advances in medical sciences 20060101
Title: 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization.
Journal: Journal of medicinal chemistry 20051103
Title: Lipopolysaccharide rapidly modifies adenosine receptor transcripts in murine and human macrophages: role of NF-kappaB in A(2A) adenosine receptor induction.
Journal: The Biochemical journal 20051101
Title: Adenosine A2A receptor stimulation potentiates nitric oxide release by activated microglia.
Journal: Journal of neurochemistry 20051101
Title: Synthesis of [1,2,4]triazolo[1,5-a]pyrazines as adenosine A2A receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20051101
Title: Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050706
Title: Postconditioning reduces infarct size via adenosine receptor activation by endogenous adenosine.
Journal: Cardiovascular research 20050701
Title: Adenosine receptors co-operate with NMDA preconditioning to protect cerebellar granule cells against glutamate neurotoxicity.
Journal: Neuropharmacology 20050701
Title: Requisite roles of A2A receptors, nitric oxide, and KATP channels in retinal arteriolar dilation in response to adenosine.
Journal: Investigative ophthalmology & visual science 20050601
Title: Effect of sleep deprivation on righting reflex in the rat is partially reversed by administration of adenosine A1 and A2 receptor antagonists.
Journal: Anesthesiology 20050601
Title: Adenosine A2A-receptor blockade abolishes the roll-off respiratory response to hypoxia in awake lambs.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20050501
Title: A2B adenosine receptor mediates human chorionic vasoconstriction and signals through arachidonic acid cascade.
Journal: American journal of physiology. Heart and circulatory physiology 20050501
Title: In vivo adenosine receptor preconditioning reduces myocardial infarct size via subcellular ERK signaling.
Journal: American journal of physiology. Heart and circulatory physiology 20050501
Title: Adenosine A2A receptor stimulation increases angiogenesis by down-regulating production of the antiangiogenic matrix protein thrombospondin 1.
Journal: Molecular pharmacology 20050501
Title: Activation of adenosine receptors in the posterior cingulate cortex impairs memory retrieval in the rat.
Journal: Neurobiology of learning and memory 20050501
Title: Blockade of adenosine A2A receptors reverses short-term social memory impairments in spontaneously hypertensive rats.
Journal: Behavioural brain research 20050430
Title: Pharmacological characterisation of the adenosine receptor mediating increased ion transport in the mouse isolated trachea and the effect of allergen challenge.
Journal: British journal of pharmacology 20050401
Title: Adenosine agonist regulation of outward active transport of fluorescein across retinal pigment epithelium in rabbits.
Journal: Experimental eye research 20050401
Title: Novel diamino derivatives of [1,2,4]triazolo[1,5-a][1,3,5]triazine as potent and selective adenosine A2a receptor antagonists.
Journal: Journal of medicinal chemistry 20050324
Title: Modulation of short-term social memory in rats by adenosine A1 and A(2A) receptors.
Journal: Neuroscience letters 20050316
Title: Adenosine contributes to mu-opioid synaptic inhibition in rat substantia gelatinosa in vitro.
Journal: Neuroscience letters 20050311
Title: Kinetic and functional properties of [3H]ZM241385, a high affinity antagonist for adenosine A2A receptors.
Journal: Life sciences 20050211
Title: Upregulation of A2A adenosine receptor expression by TNF-alpha in PBMC of patients with CHF: a regulatory mechanism of inflammation.
Journal: Journal of cardiac failure 20050201
Title: A2A adenosine receptor induction inhibits IFN-gamma production in murine CD4+ T cells.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20050115
Title: Effects of adenosine and adenosine A2A receptor agonist on motor nerve conduction velocity and nerve blood flow in experimental diabetic neuropathy.
Journal: Neurological research 20050101
Title: Characterization of [3H]ZM 241385 binding in wild-type and adenosine A2A receptor knockout mice.
Journal: European journal of pharmacology 20041103
Title: Adenosine A1 receptors modulate the anxiolytic-like effect of ethanol in the elevated plus-maze in mice.
Journal: European journal of pharmacology 20040919
Title: Adenosine A2A receptor occupancy stimulates expression of proteins involved in reverse cholesterol transport and inhibits foam cell formation in macrophages.
Journal: Journal of leukocyte biology 20040901
Title: Striatal adenosine A(2A) receptor blockade increases extracellular dopamine release following l-DOPA administration in intact and dopamine-denervated rats.
Journal: Neuropharmacology 20040901
Title: Permissive role of adenosine A2A receptors on metabotropic glutamate receptor 5 (mGluR5)-mediated effects in the striatum.
Journal: Journal of neurochemistry 20040901
Title: Piperazine derivatives of [1,2,4]triazolo[1,5-a][1,3,5]triazine as potent and selective adenosine A2a receptor antagonists.
Journal: Journal of medicinal chemistry 20040812
Title: [3H]OSIP339391, a selective, novel, and high affinity antagonist radioligand for adenosine A2B receptors.
Journal: Biochemical pharmacology 20040715
Title: Adenosine's role in hypercapnia-evoked cerebral vasodilation in the rat.
Journal: Neuroscience letters 20040715
Title: Adenosine A2A receptor blockade differentially influences excitotoxic mechanisms at pre- and postsynaptic sites in the rat striatum.
Journal: Journal of neuroscience research 20040701
Title: Comparison of inhibitory activity of isomeric triazolopyridine derivatives towards adenosine receptor subtypes or do similar structures reveal similar bioactivities?
Journal: Bioorganic & medicinal chemistry letters 20040621
Title: A2A adenosine receptor activation improves survival in mouse models of endotoxemia and sepsis.
Journal: The Journal of infectious diseases 20040515
Title: The role of intraspinal adenosine A1 receptors in sympathetic regulation.
Journal: European journal of pharmacology 20040510
Title: Role of adenosine A2A receptor in the regulation of gastric somatostatin release.
Journal: The Journal of pharmacology and experimental therapeutics 20040501
Title: AMPA receptor-mediated presynaptic inhibition at cerebellar GABAergic synapses: a characterization of molecular mechanisms.
Journal: The European journal of neuroscience 20040501
Title: Endogenous adenosine modulates epileptiform activity in rat hippocampus in a receptor subtype-dependent manner.
Journal: The European journal of neuroscience 20040501
Title: Adenosine A 2A receptor antagonists prevent the increase in striatal glutamate levels induced by glutamate uptake inhibitors.
Journal: Journal of neurochemistry 20040401
Title: Activation of adenosine A2A receptor facilitates brain-derived neurotrophic factor modulation of synaptic transmission in hippocampal slices.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040324
Title: Neutrophils both reduce and increase permeability in a cell culture model of the blood-brain barrier.
Journal: Brain research 20040220
Title: Protection from ischemic liver injury by activation of A2A adenosine receptors during reperfusion: inhibition of chemokine induction.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20040201
Title: Binding of tritiated and radioiodinated ZM241,385 to brain A2A adenosine receptors.
Journal: Nuclear medicine and biology 20040201
Title: Adenosine administration produces an antidepressant-like effect in mice: evidence for the involvement of A1 and A2A receptors.
Journal: Neuroscience letters 20040123
Title: Input-specific modulation of neurotransmitter release in the lateral horn of the spinal cord via adenosine receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040107
Title: Adenosine A2A receptors and depression.
Journal: Neurology 20031209
Title: Modulation of A2A adenosine receptors and associated Galphas proteins by ZM 241385 treatment of porcine coronary artery.
Journal: Journal of cardiovascular pharmacology 20031201
Title: Involvement of adenosine A1 receptors in forced walking stress-induced analgesia in mice.
Journal: Methods and findings in experimental and clinical pharmacology 20031201
Title: Effect of taurine deficiency on adenosine receptor-mediated relaxation of the rat aorta.
Journal: Vascular pharmacology 20031101
Title: LTP-induced depression of response to hypoxia in hippocampus: effects of adenosine receptor activation.
Journal: Neuroreport 20031006
Title: The effect of caffeine on peripheral vascular resistance in isolated perfused guinea pig hind limbs.
Journal: Journal of cardiovascular pharmacology 20031001
Title: Adenosine-A2a receptor down-regulates cerebral smooth muscle L-type Ca2+ channel activity via protein tyrosine phosphatase, not cAMP-dependent protein kinase.
Journal: Molecular pharmacology 20030901
Title: Brief, repeated, oxygen-glucose deprivation episodes protect neurotransmission from a longer ischemic episode in the in vitro hippocampus: role of adenosine receptors.
Journal: British journal of pharmacology 20030901
Title: Effects of adenosine receptor antagonists on pial arteriolar dilation during carbon dioxide inhalation.
Journal: European journal of pharmacology 20030829
Title: Enhanced adenosine A2A receptor facilitation of synaptic transmission in the hippocampus of aged rats.
Journal: Journal of neurophysiology 20030801
Title: Functional expression of adenosine A2A and A3 receptors in the mouse dendritic cell line XS-106.
Journal: European journal of pharmacology 20030801
Title: Selective A2A, but not A1 adenosine antagonists enhance the anticataleptic action of trihexyphenidyl in rats.
Journal: Neuroscience letters 20030731
Title: Adenosine A 2B receptors modulate cAMP levels and induce CREB but not ERK1/2 and p38 phosphorylation in rat skeletal muscle cells.
Journal: Biochemical and biophysical research communications 20030718
Title: Involvement of adenosine A1 and A2A receptors in the motor effects of caffeine after its acute and chronic administration.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030701
Title: The human D2 dopamine receptor synergizes with the A2A adenosine receptor to stimulate adenylyl cyclase in PC12 cells.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030701
Title: Rapid modification of the glycocalyx caused by ischemia-reperfusion is inhibited by adenosine A2A receptor activation.
Journal: American journal of physiology. Heart and circulatory physiology 20030601
Title: Induction of neurite outgrowth in PC12 cells by the bacterial nucleoside N6-methyldeoxyadenosine is mediated through adenosine A2a receptors and via cAMP and MAPK signaling pathways.
Journal: Biochemical and biophysical research communications 20030516
Title: Adenosine receptors mediate glutamate-evoked arteriolar dilation in the rat cerebral cortex.
Journal: American journal of physiology. Heart and circulatory physiology 20030501
Title: Neuroprotection by caffeine and adenosine A2A receptor blockade of beta-amyloid neurotoxicity.
Journal: British journal of pharmacology 20030401
Title: Changes of peripheral A2A adenosine receptors in chronic heart failure and cardiac transplantation.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030201
Title: Regional differences in the adenosine A(2) receptor-mediated modulation of contractions in rat vas deferens.
Journal: European journal of pharmacology 20030124
Title: Low ethanol sensitivity and increased ethanol consumption in mice lacking adenosine A2A receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20021201
Title: Effects of doxazosin and propranolol on A2A adenosine receptors in essential hypertension.
Journal: Hypertension (Dallas, Tex. : 1979) 20021201
Title: Localization of adenosine A2A-receptors in rat brain with [3H]ZM-241385.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20021101
Title: Transducing system operated by adenosine A(2A) receptors to facilitate acetylcholine release in the rat hippocampus.
Journal: European journal of pharmacology 20021101
Title: KF24345, an adenosine uptake inhibitor, ameliorates the severity and mortality of lethal acute pancreatitis via endogenous adenosine in mice.
Journal: European journal of pharmacology 20021101
Title: Characterization of adenosine receptors mediating the vasodilator effects of adenosine receptor agonists in the microvasculature of the hamster cheek pouch in vivo.
Journal: Autonomic & autacoid pharmacology 20020801
Title: Facilitation of noradrenaline release by adenosine A(2A) receptors in the epididymal portion and adenosine A(2B) receptors in the prostatic portion of the rat vas deferens.
Journal: European journal of pharmacology 20020712
Title: Selective allosteric enhancement of agonist binding and function at human A3 adenosine receptors by a series of imidazoquinoline derivatives.
Journal: Molecular pharmacology 20020701
Title: Synergistic up-regulation of vascular endothelial growth factor expression in murine macrophages by adenosine A(2A) receptor agonists and endotoxin.
Journal: The American journal of pathology 20020601
Title: Effects of adenosine receptor agonists on guinea-pig isolated working hearts and the role of endothelium and NO.
Journal: The Journal of pharmacy and pharmacology 20020601
Title: Adenosine A(2A) receptors mediate hypoxic inhibition of fetal breathing in sheep.
Journal: American journal of obstetrics and gynecology 20020401
Title: Effects of CGS 21680, a selective adenosine A2A receptor agonist, on allergic airways inflammation in the rat.
Journal: European journal of pharmacology 20020308
Title: Functional characterization of adenosine receptors and coupling to ATP-sensitive K+ channels in Guinea pig urinary bladder smooth muscle.
Journal: The Journal of pharmacology and experimental therapeutics 20020301
Title: Adenosine A(2A) receptors in portal hypertension: their role in the abnormal response to adenosine of the cranial mesenteric artery in rabbits.
Journal: British journal of pharmacology 20020301
Title: KF24345, an adenosine uptake inhibitor, suppresses lipopolysaccharide-induced tumor necrosis factor-alpha production and leukopenia via endogenous adenosine in mice.
Journal: The Journal of pharmacology and experimental therapeutics 20020101
Title: Purification and characterization of the human adenosine A(2a) receptor functionally expressed in Escherichia coli.
Journal: European journal of biochemistry 20020101
Title: Hippocampal injury and neurobehavioral deficits following hyperglycemic cerebral ischemia: effect of theophylline and ZM 241385.
Journal: Journal of neurosurgery 20020101
Title: Adenosine A(2A) receptor facilitation of hippocampal synaptic transmission is dependent on tonic A(1) receptor inhibition.
Journal: Neuroscience 20020101
Title: Purines and neuroprotection.
Journal: Advances in experimental medicine and biology 20020101
Title: Adenosine inhibits excitatory transmission to substantia gelatinosa neurons of the adult rat spinal cord through the activation of presynaptic A(1) adenosine receptor.
Journal: Pain 20011201
Title: Solubilisation and immunoprecipitation of rat striatal adenosine A(2A) receptors.
Journal: European journal of pharmacology 20011116
Title: Effect of adenosine receptor blockade on pial arteriolar dilation during sciatic nerve stimulation.
Journal: American journal of physiology. Heart and circulatory physiology 20011101
Title: Oxygen delivery and oxygen consumption in rat hindlimb during systemic hypoxia: role of adenosine.
Journal: The Journal of physiology 20011101
Title: Adenosine-mediated hypotension in in vivo guinea-pig: receptors involved and role of NO.
Journal: British journal of pharmacology 20011001
Title: Suppression of presynaptic responses to adenosine by activation of NMDA receptors.
Journal: European journal of pharmacology 20010907
Title: Adenosine-mediated inhibition of striatal GABAergic synaptic transmission during in vitro ischaemia.
Journal: Brain : a journal of neurology 20010901
Title: Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia.
Journal: British journal of pharmacology 20010901
Title: Role of adenosine and P2 receptors in the penile tumescence in anesthetized dogs.
Journal: European journal of pharmacology 20010803
Title: AMP-activated protein kinase is highly expressed in neurons in the developing rat brain and promotes neuronal survival following glucose deprivation.
Journal: Journal of molecular neuroscience : MN 20010801
Title: Selective A(2A) adenosine receptor activation reduces skin pressure ulcer formation and inflammation.
Journal: American journal of physiology. Heart and circulatory physiology 20010701
Title: Adenosine A(1) and A(2A) receptors modulate sleep state and breathing in fetal sheep.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20010701
Title: Novel short-acting A2A adenosine receptor agonists for coronary vasodilation: inverse relationship between affinity and duration of action of A2A agonists.
Journal: The Journal of pharmacology and experimental therapeutics 20010701
Title: Receptor subtypes mediating adenosine-induced dilation of cerebral arterioles.
Journal: American journal of physiology. Heart and circulatory physiology 20010501
Title: Adenosine A(2A) receptor stimulation reduces inflammation and neointimal growth in a murine carotid ligation model.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20010501
Title: Adenosine A(2A) receptor enhances GABA(A)-mediated IPSCs in the rat globus pallidus.
Journal: The Journal of physiology 20010415
Title: [3H]MRS 1754, a selective antagonist radioligand for A(2B) adenosine receptors.
Journal: Biochemical pharmacology 20010315
Title: Absence of the adenosine A(2A) receptor or its chronic blockade decrease ethanol withdrawal-induced seizures in mice.
Journal: Neuropharmacology 20010301
Title: Cyclic AMP-dependent inhibition of human neutrophil oxidative activity by substituted 2-propynylcyclohexyl adenosine A(2A) receptor agonists.
Journal: British journal of pharmacology 20010301
Title: Functional and molecular characterization of receptor subtypes mediating coronary microvascular dilation to adenosine.
Journal: Journal of molecular and cellular cardiology 20010201
Title: [(3)H]ZM241385--an antagonist radioligand for adenosine A(2A) receptors in rat brain.
Journal: European journal of pharmacology 20010112
Title: Adenosine A(2A) receptors mediate cardiovascular responses to hypoxia in fetal sheep.
Journal: American journal of physiology. Heart and circulatory physiology 20010101
Title: Potentiation of cytokine induction of group IIA phospholipase A(2) in rat mesangial cells by ATP and adenosine via the A2A adenosine receptor.
Journal: British journal of pharmacology 20010101
Title: Inactivation of adenosine A2A receptor impairs long term potentiation in the accumbens nucleus without altering basal synaptic transmission.
Journal: Neuroscience 20010101
Title: Role of endothelium in ischaemia-induced myocardial dysfunction of isolated working hearts: cardioprotection by activation of adenosine A(2A) receptors.
Journal: Journal of autonomic pharmacology 20010101
Title: Why are A(2B) receptors low-affinity adenosine receptors? Mutation of Asn273 to Tyr increases affinity of human A(2B) receptor for 2-(1-Hexynyl)adenosine.
Journal: Molecular pharmacology 20001201
Title: Site-directed mutagenesis studies of human A(2A) adenosine receptors: involvement of glu(13) and his(278) in ligand binding and sodium modulation.
Journal: Biochemical pharmacology 20000901
Title: Use of the triazolotriazine [3H]ZM 241385 as a radioligand at recombinant human A2B adenosine receptors.
Journal: Drug design and discovery 19991101
Title: Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells.
Journal: Molecular pharmacology 19991001
Title: Comparison of CGS 15943, ZM 241385 and SCH 58261 as antagonists at human adenosine receptors.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 19990101
Title: 125I-4-(2-[7-amino-2-[2-furyl][1,2,4]triazolo[2,3-a][1,3,5] triazin-5-yl-amino]ethyl)phenol, a high affinity antagonist radioligand selective for the A2a adenosine receptor.
Journal: Molecular pharmacology 19951201
