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14277-97-5,MFCD04221174
Catalog No.:AA007Z71

14277-97-5 | Domoic acid

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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA007Z71
Chemical Name:
Domoic acid
CAS Number:
14277-97-5
Molecular Formula:
C15H21NO6
Molecular Weight:
311.3303
MDL Number:
MFCD04221174
SMILES:
OC(=O)C[C@H]1[C@H](CN[C@@H]1C(=O)O)C(=CC=C[C@H](C(=O)O)C)C
Properties
Computed Properties
 
Complexity:
510  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Defined Bond Stereocenter Count:
2  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
7  
XLogP3:
-1.3  

Literature

Title: Fetal domoic acid exposure affects lateral amygdala neurons, diminishes social investigation and alters sensory-motor gating.

Journal: Neurotoxicology 20160301

Title: Influences of domoic Acid exposure on cardiac development and the expression of cardiovascular relative genes in zebrafish (Daniorerio) embryos.

Journal: Journal of biochemical and molecular toxicology 20150601

Title: Low-level domoic acid protects mouse cerebellar granule neurons from acute neurotoxicity: role of glutathione.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20130401

Title: Enhanced expression of WD repeat-containing protein 35 (WDR35) stimulated by domoic acid in rat hippocampus: involvement of reactive oxygen species generation and p38 mitogen-activated protein kinase activation.

Journal: BMC neuroscience 20130101

Title: Algal toxins and reverse osmosis desalination operations: laboratory bench testing and field monitoring of domoic acid, saxitoxin, brevetoxin and okadaic acid.

Journal: Water research 20121201

Title: Chemical toxins that cause seizures.

Journal: Neurotoxicology 20121201

Title: Exposure to domoic acid through shellfish consumption in Belgium.

Journal: Environment international 20121115

Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Journal: Bioorganic & medicinal chemistry 20121115

Title: Evaluation of circulating eosinophil count and adrenal gland function in California sea lions naturally exposed to domoic acid.

Journal: Journal of the American Veterinary Medical Association 20121001

Title: Molecular and pharmacological evidence for a facilitatory functional role of pre-synaptic GLUK2/3 kainate receptors on GABA release in rat trigeminal caudal nucleus.

Journal: European journal of pain (London, England) 20120901

Title: Impact of copper exposure on Pseudo-nitzschia spp. physiology and domoic acid production.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20120815

Title: Small interfering RNA-mediated knockdown of protein kinase C zeta attenuates domoic acid-induced cognitive deficits in mice.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120701

Title: Low-dose neonatal domoic acid causes persistent changes in behavioural and molecular indicators of stress response in rats.

Journal: Behavioural brain research 20120501

Title: Quantification of domoic acid in shellfish samples by capillary electrophoresis-based enzyme immunoassay with electrochemical detection.

Journal: Toxicon : official journal of the International Society on Toxinology 20120501

Title: Enhanced neurogenesis in organotypic cultures of rat hippocampus after transient subfield-selective excitotoxic insult induced by domoic acid.

Journal: Neuroscience 20120419

Title: Toxicokinetics of domoic acid in the fetal rat.

Journal: Toxicology 20120329

Title: Optimization of solid-phase extraction and liquid chromatography-tandem mass spectrometry for the determination of domoic acid in seawater, phytoplankton, and mammalian fluids and tissues.

Journal: Analytica chimica acta 20120217

Title: Purple sweet potato color attenuates domoic acid-induced cognitive deficits by promoting estrogen receptor-α-mediated mitochondrial biogenesis signaling in mice.

Journal: Free radical biology & medicine 20120201

Title: [Development of direct competitive enzyme-linked immunosorbent assay for the determination of domoic acid].

Journal: Huan jing ke xue= Huanjing kexue 20120201

Title: Domoic acid induced status epilepticus promotes aggressive behavior in rats.

Journal: Physiology & behavior 20120118

Title: Endangered North Atlantic right whales (Eubalaena glacialis) experience repeated, concurrent exposure to multiple environmental neurotoxins produced by marine algae.

Journal: Environmental research 20120101

Title: Condensation of the isoprenoid and amino precursors in the biosynthesis of domoic acid.

Journal: Toxicon : official journal of the International Society on Toxinology 20120101

Title: High CO2 and silicate limitation synergistically increase the toxicity of Pseudo-nitzschia fraudulenta.

Journal: PloS one 20120101

Title: A novel antibody-based biomarker for chronic algal toxin exposure and sub-acute neurotoxicity.

Journal: PloS one 20120101

Title: Comparative analysis of three brevetoxin-associated bottlenose dolphin (Tursiops truncatus) mortality events in the Florida Panhandle region (USA).

Journal: PloS one 20120101

Title: Cell-based measurements to assess physiological status of Pseudo-nitzschia multiseries, a toxic diatom.

Journal: Research in microbiology 20111101

Title: Modulation of neurite outgrowth by activation of calcium-permeable kainate receptors expressed by rat nociceptive-like dorsal root ganglion neurons.

Journal: Developmental neurobiology 20111001

Title: Transcellular transport of domoic acid across intestinal Caco-2 cell monolayers.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110901

Title: Rapid behavioural diagnosis of domoic acid toxicosis in California sea lions.

Journal: Biology letters 20110823

Title: [Development of colloidal gold immunochromatographic strip for rapid detection of domoic acid].

Journal: Huan jing ke xue= Huanjing kexue 20110801

Title: Ischemic cardiomyopathy following seizure induction by domoic Acid.

Journal: The American journal of pathology 20110701

Title: Nickel-catalyzed cyclizations of enoates and chiral allenes: an approach to domoic acid.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20110527

Title: Molecularly imprinted polymer for selective extraction of domoic acid from seafood coupled with high-performance liquid chromatographic determination.

Journal: Talanta 20110515

Title: A mussel tissue certified reference material for multiple phycotoxins. Part 3: homogeneity and stability.

Journal: Analytical and bioanalytical chemistry 20110501

Title: Altered social interaction in adult rats following neonatal treatment with domoic acid.

Journal: Physiology & behavior 20110301

Title: Effects of COX inhibitors on neurodegeneration and survival in mice exposed to the marine neurotoxin domoic acid.

Journal: Neuroscience letters 20110103

Title: Domoic acid induced seizures progress to a chronic state of epilepsy in rats.

Journal: Toxicon : official journal of the International Society on Toxinology 20110101

Title: Defining and modeling known adverse outcome pathways: Domoic acid and neuronal signaling as a case study.

Journal: Environmental toxicology and chemistry 20110101

Title: Application of micro-electrode arrays (MEAs) as an emerging technology for developmental neurotoxicity: evaluation of domoic acid-induced effects in primary cultures of rat cortical neurons.

Journal: Neurotoxicology 20110101

Title: Concurrent exposure of bottlenose dolphins (Tursiops truncatus) to multiple algal toxins in Sarasota Bay, Florida, USA.

Journal: PloS one 20110101

Title: Analytical approaches for an important shellfish poisoning agent: domoic Acid.

Journal: Journal of agricultural and food chemistry 20101124

Title: Domoic acid--a new toxin in the Croatian Adriatic shellfish toxin profile.

Journal: Molecules (Basel, Switzerland) 20101008

Title: Domoic acid uptake and elimination kinetics in oysters and mussels in relation to body size and anatomical distribution of toxin.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20101001

Title: A protozoal-associated epizootic impacting marine wildlife: mass-mortality of southern sea otters (Enhydra lutris nereis) due to Sarcocystis neurona infection.

Journal: Veterinary parasitology 20100920

Title: Magnetic resonance imaging quality and volumes of brain structures from live and postmortem imaging of California sea lions with clinical signs of domoic acid toxicosis.

Journal: Diseases of aquatic organisms 20100917

Title: Neonatal exposure to low-dose domoic acid lowers seizure threshold in adult rats.

Journal: Neuroscience 20100915

Title: In vivo seizure induction and affinity studies of domoic acid and isodomoic acids-D, -E and -F.

Journal: Neuropharmacology 20100901

Title: Domoic acid as a developmental neurotoxin.

Journal: Neurotoxicology 20100901

Title: Domoic acid and human exposure risks: a review.

Journal: Toxicon : official journal of the International Society on Toxinology 20100815

Title: Spectral analysis of electrocorticographic activity during pharmacological preconditioning and seizure induction by intrahippocampal domoic acid.

Journal: Hippocampus 20100801

Title: Subclinical effects of saxitoxin and domoic acid on aggressive behaviour and monoaminergic turnover in rainbow trout (Oncorhynchus mykiss).

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20100801

Title: Eosinophilia and biotoxin exposure in bottlenose dolphins (Tursiops truncatus) from a coastal area impacted by repeated mortality events.

Journal: Environmental research 20100801

Title: Na+/K+-ATPase inhibitor palytoxin enhances vulnerability of cultured cerebellar neurons to domoic acid via sodium-dependent mechanisms.

Journal: Journal of neurochemistry 20100701

Title: Neurological disease rises from ocean to bring model for human epilepsy to life.

Journal: Toxins 20100701

Title: In situ passive solid-phase adsorption of micro-algal biotoxins as a monitoring tool.

Journal: Current opinion in biotechnology 20100601

Title: Development of ELISAs for detecting domoic acid, okadaic acid, and saxitoxin and their applicability for the detection of marine toxins in samples collected in Belgium.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20100601

Title: Selective reductions in subpopulations of GABAergic neurons in a developmental rat model of epilepsy.

Journal: Brain research 20100517

Title: Feeding mechanics as the basis for differential uptake of the neurotoxin domoic acid by oysters, Crassostrea virginica, and mussels, Mytilus edulis.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20100415

Title: Antioxidant enzyme activity and lipid peroxidation in liver and gill tissues of Nile tilapia (Oreochromis niloticus) following in vivo exposure to domoic acid.

Journal: Toxicon : official journal of the International Society on Toxinology 20100401

Title: Enhancement of domoic acid neurotoxicity on Diptera larvae bioassay by marine fungal metabolites.

Journal: Toxicon : official journal of the International Society on Toxinology 20100401

Title: Zebrafish seizure model identifies p,p -DDE as the dominant contaminant of fetal California sea lions that accounts for synergistic activity with domoic acid.

Journal: Environmental health perspectives 20100401

Title: Immunomodulatory effects upon in vitro exposure of California sea lion and southern sea otter peripheral blood leukocytes to domoic acid.

Journal: Journal of wildlife diseases 20100401

Title: Environmental risk factors for temporal lobe epilepsy--is prenatal exposure to the marine algal neurotoxin domoic acid a potentially preventable cause?

Journal: Medical hypotheses 20100301

Title: Intracellular domoic acid production in Pseudo-nitzschia multistriata isolated from the Gulf of Naples (Tyrrhenian Sea, Italy).

Journal: Toxicon : official journal of the International Society on Toxinology 20100101

Title: Decrease of marine toxin content in bivalves by industrial processes.

Journal: Toxicon : official journal of the International Society on Toxinology 20100101

Title: Domoic acid: neurobehavioral consequences of exposure to a prevalent marine biotoxin.

Journal: Neurotoxicology and teratology 20100101

Title: Amnesic shellfish poisoning (ASP) toxins in plankton and molluscs from Luanda Bay, Angola.

Journal: Toxicon : official journal of the International Society on Toxinology 20100101

Title: Crassostrea virginica grazing on toxic and non-toxic diatoms.

Journal: Toxicon : official journal of the International Society on Toxinology 20100101

Title: Distribution and linkage of domoic acid (amnesic shellfish poisoning toxins) in subcellular fractions of the digestive gland of the scallop Pecten maximus.

Journal: Toxicon : official journal of the International Society on Toxinology 20100101

Title: Cloning and characterization of glutamate receptors in Californian sea lions (Zalophus californianus).

Journal: Marine drugs 20100101

Title: Toxic effects of domoic acid in the seabream Sparus aurata.

Journal: Marine drugs 20100101

Title: Reductions in paradoxical sleep time in adult rats treated neonatally with low dose domoic acid.

Journal: Behavioural brain research 20091228

Title: The occurrence of domoic acid linked to a toxic diatom bloom in a new potential vector: the tunicate Pyura chilensis (piure).

Journal: Toxicon : official journal of the International Society on Toxinology 20091101

Title: Amnesic shellfish poisoning toxin stimulates the transcription of CYP1A possibly through AHR and ARNT in the liver of red sea bream Pagrus major.

Journal: Marine pollution bulletin 20091101

Title: Furthering pharmacological and physiological assessment of the glutamatergic receptors at the Drosophila neuromuscular junction.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20091101

Title: Domoic acid induces a long-lasting enhancement of CA1 field responses and impairs tetanus-induced long-term potentiation in rat hippocampal slices.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090901

Title: Bimolecular rate constant determination for the reaction of hydroxyl radicals with domoic and kainic acid in aqueous solution.

Journal: Environmental science & technology 20090901

Title: [A indirect competitive ELISA to detect domoic acid in seawater and shellfish].

Journal: Wei sheng yan jiu = Journal of hygiene research 20090901

Title: Analysis of trace levels of domoic acid in seawater and plankton by liquid chromatography without derivatization, using UV or mass spectrometry detection.

Journal: Journal of chromatography. A 20090807

Title: Effects of low dose neonatal domoic acid administration on behavioural and physiological response to mild stress in adult rats.

Journal: Physiology & behavior 20090804

Title: Effect of some habitual cooking processes on the domoic acid concentration in the cockle (Cerastoderma edule) and Manila clam (Ruditapes philippinarum).

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20090701

Title: Development of a novel antibody probe useful for domoic acid detection.

Journal: Biosensors & bioelectronics 20090615

Title: Quantification of domoic acid in shellfish tissues by pressurized capillary electrochromatography.

Journal: Journal of separation science 20090601

Title: Risk assessment of the amnesic shellfish poison, domoic acid, on animals and humans.

Journal: Journal of environmental biology 20090501

Title: Muscarinic receptors prevent oxidative stress-mediated apoptosis induced by domoic acid in mouse cerebellar granule cells.

Journal: Journal of neurochemistry 20090401

Title: Persistent changes in learning and memory in rats following neonatal treatment with domoic acid.

Journal: Physiology & behavior 20090323

Title: Photocatalytic properties of nanocrystalline titanium dioxide films in the degradation of domoic acid in aqueous solution: potential for use in molluscan shellfish biotoxin depuration facilities.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20090201

Title: Deaths in rockhopper penguins.

Journal: The Veterinary record 20090124

Title: Wildlife biology. Confused pelicans may have lingered too long up north.

Journal: Science (New York, N.Y.) 20090123

Title: Gene expression profiles in zebrafish brain after acute exposure to domoic acid at symptomatic and asymptomatic doses.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090101

Title: Characterization of a degenerative cardiomyopathy associated with domoic acid toxicity in California sea lions (Zalophus californianus).

Journal: Veterinary pathology 20090101

Title: DDT exposure of zebrafish embryos enhances seizure susceptibility: relationship to fetal p,p'-DDE burden and domoic acid exposure of California sea lions.

Journal: Environmental health perspectives 20090101

Title: The role of domoic acid in abortion and premature parturition of California sea lions (Zalophus californianus) on San Miguel Island, California.

Journal: Journal of wildlife diseases 20090101

Title: Association of an unusual marine mammal mortality event with Pseudo-nitzschia spp. Blooms along the southern California coastline.

Journal: Journal of wildlife diseases 20090101

Title: Intrauterine environment-genome interaction and children's development (2): Brain structure impairment and behavioral disturbance induced in male mice offspring by a single intraperitoneal administration of domoic acid (DA) to their dams.

Journal: The Journal of toxicological sciences 20090101

Title: Determination of dissolved domoic acid in seawater with reversed-phase extraction disks and rapid resolution liquid chromatography tandem mass spectrometry with head-column trapping.

Journal: Journal of chromatography. A 20081226

Title: Comparative toxicity to mice of domoic acid and isodomoic acids A, B and C.

Journal: Toxicon : official journal of the International Society on Toxinology 20081215

Title: Determination of domoic acid in mussels by HPLC with post-column derivatization using 4-chloro-7-nitrobenzo-2-oxa-1,3-diazole (NBD-Cl) and fluorescence detection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081215

Title: Domoic acid induces direct DNA damage and apoptosis in Caco-2 cells: recent advances.

Journal: Environmental toxicology 20081201

Title: In vivo seizure induction and pharmacological preconditioning by domoic acid and isodomoic acids A, B and C.

Journal: Neuropharmacology 20081201

Title: Immunomodulatory effects of domoic acid differ between in vivo and in vitro exposure in mice.

Journal: Marine drugs 20081201

Title: [Effects of domoic acid on membrane function of primary cultured rat glial cells].

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20081201

Title: In vivo genotoxicity testing of the amnesic shellfish poison (domoic acid) in piscine erythrocytes using the micronucleus test and the comet assay.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20081111

Title: Domoic acid impairment of cardiac energetics.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20081001

Title: Mutations to the kainate receptor subunit GluR6 binding pocket that selectively affect domoate binding.

Journal: Molecular pharmacology 20081001

Title: Comparative study of the use of neuroblastoma cells (Neuro-2a) and neuroblastomaxglioma hybrid cells (NG108-15) for the toxic effect quantification of marine toxins.

Journal: Toxicon : official journal of the International Society on Toxinology 20080915

Title: Chemo-enzymatic synthesis of a series of 2,4-syn-functionalized (S)-glutamate analogues: new insight into the structure-activity relation of ionotropic glutamate receptor subtypes 5, 6, and 7.

Journal: Journal of medicinal chemistry 20080724

Title: Domoic acid excretion in dungeness crabs, razor clams and mussels.

Journal: Marine environmental research 20080701

Title: Domoic acid induced spinal cord lesions in adult mice: evidence for the possible molecular pathways of excitatory amino acids in spinal cord lesions.

Journal: Neurotoxicology 20080701

Title: [Aquatic biotoxins in relation to food poisonings].

Journal: Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology 20080701

Title: Low dose domoic acid in neonatal rats abolishes nicotine induced conditioned place preference during late adolescence.

Journal: Amino acids 20080601

Title: Altered pre-pulse inhibition in adult rats treated neonatally with domoic acid.

Journal: Amino acids 20080601

Title: Transcriptional responses of xenobiotic metabolizing enzymes, HSP70 and Na+/K+ -ATPase in the liver of rabbitfish (Siganus oramin) intracoelomically injected with amnesic shellfish poisoning toxin.

Journal: Environmental toxicology 20080601

Title: Apoptosis induced by domoic acid in mouse cerebellar granule neurons involves activation of p38 and JNK MAP kinases.

Journal: Neurochemistry international 20080501

Title: Development of a high-affinity anti-domoic acid sheep scFv and its use in detection of the toxin in shellfish.

Journal: Analytical chemistry 20080501

Title: Inorganic carbon acquisition in potentially toxic and non-toxic diatoms: the effect of pH-induced changes in seawater carbonate chemistry.

Journal: Physiologia plantarum 20080501

Title: Extraction of domoic acid from seawater and urine using a resin based on 2-(trifluoromethyl)acrylic acid.

Journal: Analytica chimica acta 20080303

Title: Regional susceptibility to domoic acid in primary astrocyte cells cultured from the brain stem and hippocampus.

Journal: Marine drugs 20080301

Title: Domoic acid toxicologic pathology: a review.

Journal: Marine drugs 20080301

Title: In utero domoic acid toxicity: a fetal basis to adult disease in the California sea lion (Zalophus californianus).

Journal: Marine drugs 20080301

Title: Novel symptomatology and changing epidemiology of domoic acid toxicosis in California sea lions (Zalophus californianus): an increasing risk to marine mammal health.

Journal: Proceedings. Biological sciences 20080207

Title: Altered responses to novelty and drug reinforcement in adult rats treated neonatally with domoic acid.

Journal: Physiology & behavior 20080128

Title: Glutathione levels modulate domoic acid induced apoptosis in mouse cerebellar granule cells.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20071201

Title: Adsorption of domoic acid to marine sediments and clays.

Journal: Journal of environmental monitoring : JEM 20071201

Title: Maternal-fetal transfer of domoic acid in rats at two gestational time points.

Journal: Environmental health perspectives 20071201

Title: Effects of algal-produced neurotoxins on metabolic activity in telencephalon, optic tectum and cerebellum of Atlantic salmon (Salmo salar).

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20071130

Title: Photostability of kainic acid in seawater.

Journal: Journal of agricultural and food chemistry 20071128

Title: Simple and effective 3D recognition of domoic acid using a molecularly imprinted polymer.

Journal: Journal of the American Chemical Society 20071107

Title: Embryonic exposure to domoic Acid increases the susceptibility of zebrafish larvae to the chemical convulsant pentylenetetrazole.

Journal: Environmental health perspectives 20071101

Title: Occurrence and seasonal variations of algal toxins in water, phytoplankton and shellfish from North Stradbroke Island, Queensland, Australia.

Journal: Marine environmental research 20071001

Title: Isodomoic acids A and C exhibit low KA receptor affinity and reduced in vitro potency relative to domoic acid in region CA1 of rat hippocampus.

Journal: Toxicon : official journal of the International Society on Toxinology 20071001

Title: Determination of domoic acid in seawater and phytoplankton by liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. A 20070907

Title: Domoic acid preconditioning and seizure induction in young and aged rats.

Journal: Epilepsy research 20070901

Title: Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: structures of the ligand-binding core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid.

Journal: The Journal of biological chemistry 20070831

Title: Non-resonance micro-Raman spectroscopic studies on crystalline domoic acid and its aqueous solutions.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070801

Title: Development of a monoclonal antibody against domoic acid and its application in enzyme-linked immunosorbent assay and colloidal gold immunostrip.

Journal: Journal of agricultural and food chemistry 20070627

Title: Development of a pressurised liquid extraction and liquid chromatography with electrospray ionization-tandem mass spectrometry method for the determination of domoic acid in shellfish.

Journal: Journal of chromatography. A 20070622

Title: Effect of addition of antibiotics and an antioxidant on the stability of tissue reference materials for domoic acid, the amnesic shellfish poison.

Journal: Analytical and bioanalytical chemistry 20070401

Title: Feasibility of gamma irradiation as a stabilisation technique in the preparation of tissue reference materials for a range of shellfish toxins.

Journal: Analytical and bioanalytical chemistry 20070401

Title: Freeze-drying for the stabilisation of shellfish toxins in mussel tissue (Mytilus edulis) reference materials.

Journal: Analytical and bioanalytical chemistry 20070401

Title: Uptake, tissue distribution and excretion of domoic acid after oral exposure in coho salmon (Oncorhynchus kisutch).

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20070310

Title: Optimisation of production of a domoic acid-binding scFv antibody fragment in Escherichia coli using molecular chaperones and functional immobilisation on a mesoporous silicate support.

Journal: Protein expression and purification 20070301

Title: Exposure to domoic acid affects larval development of king scallop Pecten maximus (Linnaeus, 1758).

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20070227

Title: Solid-phase extraction-fluorimetric high performance liquid chromatographic determination of domoic acid in natural seawater mediated by an amorphous titania sorbent.

Journal: Analytica chimica acta 20070130

Title: Gender-based changes in cognition and emotionality in a new rat model of epilepsy.

Journal: Amino acids 20070101

Title: Hippocampal mossy fiber sprouting and elevated trkB receptor expression following systemic administration of low dose domoic acid during neonatal development.

Journal: Hippocampus 20070101

Title: Single-laboratory validation of the biosense direct competitive enzyme-linked immunosorbent assay (ELISA) for determination of domoic acid toxins in shellfish.

Journal: Journal of AOAC International 20070101

Title: Determination of domoic acid toxins in shellfish by biosense ASP ELISA--a direct competitive enzyme-linked immunosorbent assay: collaborative study.

Journal: Journal of AOAC International 20070101

Title: [Phycotoxins of ASP, PSP and DSP groups in aquaris organisms].

Journal: Voprosy pitaniia 20070101

Title: Neurotoxicity of domoic Acid in cerebellar granule neurons in a genetic model of glutathione deficiency.

Journal: Molecular pharmacology 20061201

Title: Presynaptic inhibition by kainate receptors converges mechanistically with presynaptic inhibition by adenosine and GABAB receptors.

Journal: Neuropharmacology 20061101

Title: Interface interactions modulating desensitization of the kainate-selective ionotropic glutamate receptor subunit GluR6.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060927

Title: Adsorption and activity of a domoic acid binding antibody fragment on mesoporous silicates.

Journal: The journal of physical chemistry. B 20060921

Title: Role of the plasma membrane calcium adenosine triphosphatase on domoate-induced intracellular acidification in primary cultures of cerebelar granule cells.

Journal: Journal of neuroscience research 20060801

Title: Harmful algal bloom toxins alter c-Fos protein expression in the brain of killifish, Fundulus heteroclitus.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20060720

Title: Absence of neurotoxic effects in leopard sharks, Triakis semifasciata, following domoic acid exposure.

Journal: Toxicon : official journal of the International Society on Toxinology 20060601

Title: Presynaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors modulate release of inhibitory amino acids in rat spinal cord dorsal horn.

Journal: Neuroscience 20060512

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Determination of domoic acid by on-line coupled capillary isotachophoresis with capillary zone electrophoresis.

Journal: Journal of chromatography. A 20060428

Title: Role of Fe(III), phosphate, dissolved organic matter, and nitrate during the photodegradation of domoic acid in the marine environment.

Journal: Environmental science & technology 20060401

Title: Tissue distribution and effects of heat treatments on the content of domoic acid in blue mussels, Mytilus edulis.

Journal: Toxicon : official journal of the International Society on Toxinology 20060315

Title: Comparative study of Domoic Acid and Okadaic Acid induced-chromosomal abnormalities in the Caco-2 cell line.

Journal: International journal of environmental research and public health 20060301

Title: Marine toxin hinders cognitive development.

Journal: Environmental health perspectives 20060201

Title: Sequential involvement of distinct glutamate receptors in domoic acid-induced neurotoxicity in rat mixed cortical cultures: effect of multiple dose/duration paradigms, chronological age, and repeated exposure.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060101

Title: Histopathological and molecular changes produced by hippocampal microinjection of domoic acid.

Journal: Neurotoxicology and teratology 20060101

Title: Comparative analysis of purified Pacific and Caribbean ciguatoxin congeners and related marine toxins using a modified ELISA technique.

Journal: Journal of clinical laboratory analysis 20060101

Title: Immunobiosensor detection of domoic acid as a screening test in bivalve molluscs: comparison with liquid chromatography-based analysis.

Journal: Journal of AOAC International 20060101

Title: Persistent neurobehavioral effects of early postnatal domoic acid exposure in rats.

Journal: Neurotoxicology and teratology 20060101

Title: Amnesic shellfish poisoning toxins in bivalve molluscs in Ireland.

Journal: Toxicon : official journal of the International Society on Toxinology 20051215

Title: Production of isodomoic acids A and B as major toxin components of a pennate diatom Nitzschia navis-varingica.

Journal: Toxicon : official journal of the International Society on Toxinology 20051215

Title: Detection of domoic acid in rat serum and brain by direct competitive enzyme-linked immunosorbent assay (cELISA).

Journal: Analytical and bioanalytical chemistry 20051101

Title: Cloning, expression and characterisation of a single-chain Fv antibody fragment against domoic acid in Escherichia coli.

Journal: Journal of biotechnology 20051017

Title: Accumulation, transformation and tissue distribution of domoic acid, the amnesic shellfish poisoning toxin, in the common cuttlefish, Sepia officinalis.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20050815

Title: Quantitative 1H NMR with external standards: use in preparation of calibration solutions for algal toxins and other natural products.

Journal: Analytical chemistry 20050515

Title: [Domoic acid and human health].

Journal: Wei sheng yan jiu = Journal of hygiene research 20050501

Title: Improved high-performance liquid chromatographic method for the determination of domoic acid and analogues in shellfish: effect of pH.

Journal: Analytical and bioanalytical chemistry 20050401

Title: Ultrasensitive detection of domoic acid in mouse blood by competitive ELISA using blood collection cards.

Journal: Toxicon : official journal of the International Society on Toxinology 20050401

Title: Domoic acid transfer to milk: evaluation of a potential route of neonatal exposure.

Journal: Environmental health perspectives 20050401

Title: The synthesis of (-)-isodomoic acid C.

Journal: Journal of the American Chemical Society 20050302

Title: NMDA receptor involvement in the effects of low dose domoic acid in neonatal rats.

Journal: Amino acids 20050301

Title: Nefopam inhibits calcium influx, cGMP formation, and NMDA receptor-dependent neurotoxicity following activation of voltage sensitive calcium channels.

Journal: Amino acids 20050301

Title: Pathology of domoic acid toxicity in California sea lions (Zalophus californianus).

Journal: Veterinary pathology 20050301

Title: Evaluation of cardiac lesions and risk factors associated with myocarditis and dilated cardiomyopathy in southern sea otters (Enhydra lutris nereis).

Journal: American journal of veterinary research 20050201

Title: Committee on Natural Toxins and Food Allergens. Marine and freshwater toxins.

Journal: Journal of AOAC International 20050101

Title: Hydrophilic interaction liquid chromatography/mass spectrometry for determination of domoic acid in Adriatic shellfish.

Journal: Rapid communications in mass spectrometry : RCM 20050101

Title: Behavioral and histopathological analysis of domoic Acid administration in marmosets.

Journal: Epilepsia 20050101

Title: Multiresidue method for determination of algal toxins in shellfish: single-laboratory validation and interlaboratory study.

Journal: Journal of AOAC International 20050101

Title: Persisting behavioral consequences of prenatal domoic acid exposure in rats.

Journal: Neurotoxicology and teratology 20050101

Title: Developmental toxicity of domoic acid in zebrafish (Danio rerio).

Journal: Neurotoxicology and teratology 20050101

Title: Mapping and reconstruction of domoic acid-induced neurodegeneration in the mouse brain.

Journal: Neurotoxicology and teratology 20050101

Title: Neurohistochemical biomarkers of the marine neurotoxicant, domoic acid.

Journal: Neurotoxicology and teratology 20050101

Title: Acute phase gene expression in mice exposed to the marine neurotoxin domoic acid.

Journal: Neuroscience 20050101

Title: Surface plasmon resonance sensor for domoic acid based on grafted imprinted polymer.

Journal: Biosensors & bioelectronics 20040915

Title: Disposable immunosensor for the determination of domoic acid in shellfish.

Journal: Biosensors & bioelectronics 20040915

Title: Characterisation of the effects of ATPA, a GLU(K5) kainate receptor agonist, on GABAergic synaptic transmission in the CA1 region of rat hippocampal slices.

Journal: Neuropharmacology 20040901

Title: Development of a sensitive enzyme-linked immunosorbent assay for the determination of domoic Acid in shellfish.

Journal: Journal of agricultural and food chemistry 20040825

Title: Characterization of a domoic acid binding site from Pacific razor clam.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20040810

Title: Domoic acid enhances Bcl-2-calcineurin-inositol-1,4,5-trisphosphate receptor interactions and delayed neuronal death in rat brain slices.

Journal: Brain research 20040716

Title: Kainate receptor agonists and antagonists mediate tolerance to kainic acid and reduce high-affinity GTPase activity in young, but not aged, rat hippocampus.

Journal: Journal of neurochemistry 20040701

Title: Sensitive determination of domoic acid using high-performance liquid chromatography with electrogenerated tris(2,2'-bipyridine)ruthenium(III) chemiluminescence detection.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20040701

Title: Environmental and health effects associated with Harmful Algal Bloom and marine algal toxins in China.

Journal: Biomedical and environmental sciences : BES 20040601

Title: Amnesic shellfish poison.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040401

Title: Attenuation of baroreflex sensitivity after domoic acid lesion of the nucleus ambiguus of rats.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20040301

Title: Electroencephalographic, behavioral, and c-fos responses to acute domoic acid exposure.

Journal: Neurotoxicology and teratology 20040101

Title: Domoic acid-induced neurotoxicity in the hippocampus of adult rats.

Journal: Neurotoxicity research 20040101

Title: Low doses of domoic acid during postnatal development produce permanent changes in rat behaviour and hippocampal morphology.

Journal: Neurotoxicity research 20040101

Title: First total synthesis and stereochemical definition of isodomoic acid G.

Journal: Organic letters 20031002

Title: The neuroprotective effects of virally-derived caspase inhibitors p35 and crmA following a necrotic insult.

Journal: Neurobiology of disease 20031001

Title: Mechanisms underlying domoic acid-induced dopamine release from striatum: an in vivo microdialysis study.

Journal: Neurochemical research 20031001

Title: A potential vector of domoic acid: the swimming crab Polybius henslowii Leach (Decapoda-brachyura).

Journal: Toxicon : official journal of the International Society on Toxinology 20030801

Title: RNA synthesis-dependent potentiation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor-mediated toxicity by antihistamine terfenadine in cultured rat cerebellar neurons.

Journal: Neuroscience letters 20030717

Title: Development of a F actin-based live-cell fluorimetric microplate assay for diarrhetic shellfish toxins.

Journal: Analytical biochemistry 20030615

Title: Pharmacological properties of l-glutamate receptors associated with the crayfish hindgut.

Journal: Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20030501

Title: Neuroprotective actions of pyridoxine.

Journal: Biochimica et biophysica acta 20030411

Title: Rapid determination of domoic acid in serum and urine by liquid chromatography-electrospray tandem mass spectrometry.

Journal: Journal of agricultural and food chemistry 20030326

Title: The structural basis for kainoid selectivity at AMPA receptors revealed by low-mode docking calculations.

Journal: Bioorganic & medicinal chemistry 20030220

Title: Induction of inducible nitric oxide synthase expression in activated microglia following domoic acid (DA)-induced neurotoxicity in the rat hippocampus.

Journal: Neuroscience letters 20030220

Title: Diatom cultivation and biotechnologically relevant products. Part II: current and putative products.

Journal: Applied microbiology and biotechnology 20030201

Title: In vitro hypoxia and excitotoxicity in human brain induce calcineurin-Bcl-2 interactions.

Journal: Neuroscience 20030101

Title: Distribution of NADPH-diaphorase and expression of nNOS, N-methyl-D-aspartate receptor (NMDAR1) and non-NMDA glutamate receptor (GlutR2) genes in the neurons of the hippocampus after domoic acid-induced lesions in adult rats.

Journal: Hippocampus 20030101

Title: Protective role of melatonin in domoic acid-induced neuronal damage in the hippocampus of adult rats.

Journal: Hippocampus 20030101

Title: Amnesic shellfish poisoning toxins in shellfish: estimation of uncertainty of measurement for a liquid chromatography/tandem mass spectrometry method.

Journal: Journal of AOAC International 20030101

Title: Kainate receptors differentially regulate release at two parallel fiber synapses.

Journal: Neuron 20021024

Title: Depuration and anatomical distribution of the amnesic shellfish poisoning (ASP) toxin domoic acid in the king scallop Pecten maximus.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20021002

Title: Emerita analoga (Stimpson)--possible new indicator species for the phycotoxin domoic acid in California coastal waters.

Journal: Toxicon : official journal of the International Society on Toxinology 20020901

Title: Novel electrochemical immunosensors for seafood toxin analysis.

Journal: Toxicon : official journal of the International Society on Toxinology 20020901

Title: Age-related changes in tolerance to the marine algal excitotoxin domoic acid.

Journal: Neuropharmacology 20020901

Title: From sanddabs to blue whales: the pervasiveness of domoic acid.

Journal: Toxicon : official journal of the International Society on Toxinology 20020701

Title: Development of a protocol for determination of domoic acid in the sand crab (Emerita analoga): a possible new indicator species.

Journal: Toxicon : official journal of the International Society on Toxinology 20020501

Title: Evaluation of marine biotoxin's accumulation by Acanthocardia tuberculatum from Algarve, Portugal.

Journal: Toxicon : official journal of the International Society on Toxinology 20020501

Title: Domoic acid lesions in nucleus of the solitary tract: time-dependent recovery of hypoxic ventilatory response and peripheral afferent axonal plasticity.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020415

Title: Domoic acid toxicity in Californian sea lions (Zalophus californianus): clinical signs, treatment and survival.

Journal: The Veterinary record 20020413

Title: [Capillary electrophoretic analysis of amnesic shellfish toxin--domoic acid].

Journal: Se pu = Chinese journal of chromatography 20020301

Title: Domoic acid neurotoxicity in cultured cerebellar granule neurons is controlled preferentially by the NMDA receptor Ca(2+) influx pathway.

Journal: Brain research 20020104

Title: Domoic acid neurotoxicity in hippocampal slice cultures.

Journal: Amino acids 20020101

Title: Determination of domoic acid in shellfish by liquid chromatography with electrospray ionization and multiple tandem mass spectrometry.

Journal: Journal of chromatography. A 20011214

Title: Toxicity of domoic acid in the marine mussel Mytilus edulis.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20011112

Title: Domoic acid-induced hippocampal CA1 hyperexcitability independent of region CA3 activity.

Journal: Epilepsy research 20011101

Title: Domoic acid-induced neuronal damage in the rat hippocampus: changes in apoptosis related genes (bcl-2, bax, caspase-3) and microglial response.

Journal: Journal of neuroscience research 20011015

Title: Indirect actions of bradykinin on neonatal rat dorsal root ganglion neurones: a role for non-neuronal cells as nociceptors.

Journal: The Journal of physiology 20011001

Title: Domoic acid accumulation in French shellfish in relation to toxic species of Pseudo-nitzschia multiseries and P. pseudodelicatissima.

Journal: Toxicon : official journal of the International Society on Toxinology 20010801

Title: Circulating insulin-like growth factor I mediates the protective effects of physical exercise against brain insults of different etiology and anatomy.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010801

Title: [Determination of domoic acid in water and aquatic animals by high performance liquid chromatography].

Journal: Wei sheng yan jiu = Journal of hygiene research 20010701

Title: Brain aromatase is neuroprotective.

Journal: Journal of neurobiology 20010615

Title: Domoic acid in Portuguese shellfish and fish.

Journal: Toxicon : official journal of the International Society on Toxinology 20010601

Title: Kainate receptors depress excitatory synaptic transmission at CA3-->CA1 synapses in the hippocampus via a direct presynaptic action.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010501

Title: Inhibition of choline acetyltransferase by excitatory amino acids as a possible mechanism for cholinergic dysfunction in the central nervous system.

Journal: Journal of neurochemistry 20010501

Title: [High performance liquid chromatographic determination of domoic acid in shellfish samples].

Journal: Se pu = Chinese journal of chromatography 20010501

Title: Death of motoneurons induced by trophic deprivation or by excitotoxicity is not prevented by overexpression of SMN.

Journal: Neurobiology of disease 20010401

Title: Contributions of AMPA- and kainate-sensitive receptors to the photopic electroretinogram of the Xenopus retina.

Journal: Visual neuroscience 20010101

Title: Determination and confirmation of the amnesic shellfish poisoning toxin, domoic acid, in shellfish from Scotland by liquid chromatography and mass spectrometry.

Journal: Journal of AOAC International 20010101

Title: Effect of a short-term in vitro exposure to the marine toxin domoic acid on viability, tumor necrosis factor-alpha, matrix metalloproteinase-9 and superoxide anion release by rat neonatal microglia.

Journal: BMC pharmacology 20010101

Title: Synthesis of a series of aryl kainic acid analogs and evaluation in cells stably expressing the kainate receptor humGluR6.

Journal: Journal of medicinal chemistry 19960913

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