[1]CurrentPatentAssignee:PFIZERINC-US2013/123230,2013,A1
[2]Ruggeri,RogerB.;Buckbinder,Leonard;Bagley,ScottW.;Carpino,PhilipA.;Conn,EdwardL.;Dowling,MatthewS.;Fernando,DilinieP.;Jiao,Wenhua;Kung,DanielW.;Orr,SuviT.M.;Qi,Yingmei;Rocke,BenjaminN.;Smith,Aaron;Warmus,JosephS.;Zhang,Yan;Bowles,Daniel;Widlicka,DanielW.;Eng,Heather;Ryder,Tim;Sharma,Raman;Wolford,Angela;Okerberg,Carlin;Walters,Karen;Maurer,TristanS.;Zhang,Yanwei;Bonin,PaulD.;Spath,SamanthaN.;Xing,Gang;Hepworth,David;Ahn,Kay;Kalgutkar,AmitS.[JournalofMedicinalChemistry,2015,vol.58,#21,p.8513-8528]
[1]CurrentPatentAssignee:PFIZERINC-US2013/123230,2013,A1
[1]Ruggeri,RogerB.;Buckbinder,Leonard;Bagley,ScottW.;Carpino,PhilipA.;Conn,EdwardL.;Dowling,MatthewS.;Fernando,DilinieP.;Jiao,Wenhua;Kung,DanielW.;Orr,SuviT.M.;Qi,Yingmei;Rocke,BenjaminN.;Smith,Aaron;Warmus,JosephS.;Zhang,Yan;Bowles,Daniel;Widlicka,DanielW.;Eng,Heather;Ryder,Tim;Sharma,Raman;Wolford,Angela;Okerberg,Carlin;Walters,Karen;Maurer,TristanS.;Zhang,Yanwei;Bonin,PaulD.;Spath,SamanthaN.;Xing,Gang;Hepworth,David;Ahn,Kay;Kalgutkar,AmitS.[JournalofMedicinalChemistry,2015,vol.58,#21,p.8513-8528]
[2]CurrentPatentAssignee:PFIZERINC-US2013/123230,2013,A1Locationinpatent:Paragraph0245;0246;0247
Title: Dong JQ, et al. Pharmacokinetics and Disposition of the Thiouracil Derivative PF-06282999, an Orally Bioavailable, Irreversible Inactivator of Myeloperoxidase Enzyme, Across Animals and Humans. Drug Metab Dispos. 2016 Feb;44(2):209-19.
Title: Ruggeri RB, et al. Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based Myeloperoxidase Inhibitor for the Treatment of Cardiovascular Diseases. J Med Chem. 20
