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144598-75-4,MFCD00871802
Catalog No.:AA001JQR

144598-75-4 | Paliperidone

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Purity
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5mg
>98%(HPLC)powder
in stock  
$64.00   $45.00
- +
10mg
98%
in stock  
$90.00   $63.00
- +
25mg
>98%(HPLC)powder
in stock  
$97.00   $68.00
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50mg
98%
in stock  
$184.00   $129.00
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100mg
>98%(HPLC)powder
in stock  
$310.00   $217.00
- +
200mg
98%
in stock  
$349.00   $244.00
- +
250mg
98%
in stock  
$386.00   $270.00
- +
1g
>98%(HPLC)powder
in stock  
$1,020.00   $714.00
- +
25g
98%
in stock  
$23,931.00   $16,752.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA001JQR
Chemical Name:
Paliperidone
CAS Number:
144598-75-4
Molecular Formula:
C23H27FN4O3
Molecular Weight:
426.4839
MDL Number:
MFCD00871802
SMILES:
Fc1ccc2c(c1)onc2C1CCN(CC1)CCc1c(C)nc2n(c1=O)CCCC2O
Properties
Computed Properties
 
Complexity:
764  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
1  
XLogP3:
2.2  

Literature

Title: Evaluating the Role of Multidrug Resistance Protein 3 (MDR3) Inhibition in Predicting Drug-Induced Liver Injury Using 125 Pharmaceuticals.

Journal: Chemical research in toxicology 20170515

Title: Efficacy and Safety of the 3-Month Formulation of Paliperidone Palmitate vs Placebo for Relapse Prevention of Schizophrenia: A Randomized Clinical Trial.

Journal: JAMA psychiatry 20150801

Title: Relationship between inflammation and metabolic syndrome following treatment with paliperidone for schizophrenia.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20121203

Title: Paliperidone extended release: in adolescents with schizophrenia.

Journal: Paediatric drugs 20121201

Title: An evaluation of using rat-derived single-dose neuropharmacokinetic parameters to project accurately large animal unbound brain drug concentrations.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20121101

Title: Blonanserin, a novel atypical antipsychotic agent not actively transported as substrate by P-glycoprotein.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20121001

Title: Rabbit syndrome following discontinuation of paliperidone in a patient with schizoaffective disorder.

Journal: Journal of clinical psychopharmacology 20121001

Title: An analysis of potentially prolactin-related adverse events and abnormal prolactin values in randomized clinical trials with paliperidone palmitate.

Journal: The Annals of pharmacotherapy 20121001

Title: Solid phase microextraction and LC-MS/MS for the determination of paliperidone after stereoselective fungal biotransformation of risperidone.

Journal: Analytica chimica acta 20120912

Title: Paliperidone for irritability in adolescents and young adults with autistic disorder.

Journal: Psychopharmacology 20120901

Title: Paliperidone ER versus risperidone for neurocognitive function in patients with schizophrenia: a randomized, open-label, controlled trial.

Journal: International clinical psychopharmacology 20120901

Title: Body weight and metabolic adverse effects of asenapine, iloperidone, lurasidone and paliperidone in the treatment of schizophrenia and bipolar disorder: a systematic review and exploratory meta-analysis.

Journal: CNS drugs 20120901

Title: Second-generation long-acting injectable antipsychotic agents: an overview.

Journal: Drug and therapeutics bulletin 20120901

Title: The effect of paliperidone extended release on subjective well-being and responses in patients with schizophrenia.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20120807

Title: Population pharmacokinetic analysis of risperidone and 9-hydroxyrisperidone with genetic polymorphisms of CYP2D6 and ABCB1.

Journal: Journal of pharmacokinetics and pharmacodynamics 20120801

Title: Flexible dosing with paliperidone ER in the treatment of patients with acutely exacerbated schizophrenia: results from a single-arm, open-label study.

Journal: Current medical research and opinion 20120801

Title: Paliperidone: a review of clinical trial data and clinical implications.

Journal: Clinical drug investigation 20120801

Title: A cross-sectional study of plasma risperidone levels with risperidone long-acting injectable: implications for dopamine D2 receptor occupancy during maintenance treatment in schizophrenia.

Journal: The Journal of clinical psychiatry 20120801

Title: Pharmacokinetic-pharmacodynamic modeling of the D₂ and 5-HT (2A) receptor occupancy of risperidone and paliperidone in rats.

Journal: Pharmaceutical research 20120701

Title: Oral paliperidone extended-release: chemistry, pharmacodynamics, pharmacokinetics and metabolism, clinical efficacy, safety and tolerability.

Journal: Expert opinion on drug metabolism & toxicology 20120701

Title: Paliperidone palmitate for schizophrenia.

Journal: The Cochrane database of systematic reviews 20120613

Title: Treatment response after relapse in a placebo-controlled maintenance trial in schizophrenia.

Journal: Schizophrenia research 20120601

Title: Different impacts of aquaporin 4 and MAOA allele variation among olanzapine, risperidone, and paliperidone in schizophrenia.

Journal: Journal of clinical psychopharmacology 20120601

Title: Risperidone and total 9-hydroxyrisperidone in relation to prescribed dose and other factors: data from a therapeutic drug monitoring service, 2002-2010.

Journal: Therapeutic drug monitoring 20120601

Title: Extended-release intramuscular paliperidone palmitate: a review of its use in the treatment of schizophrenia.

Journal: Drugs 20120528

Title: Design of a long-term antipsychotic in situ forming implant and its release control method and mechanism.

Journal: International journal of pharmaceutics 20120510

Title: Combination of citalopram plus paliperidone is better than citalopram alone in the treatment of somatoform disorder: results of a 6-week randomized study.

Journal: International clinical psychopharmacology 20120501

Title: A randomized, placebo- and active-controlled study of paliperidone extended-release as maintenance treatment in patients with bipolar I disorder after an acute manic or mixed episode.

Journal: Journal of affective disorders 20120501

Title: Long-acting injectable antipsychotics for the maintenance treatment of bipolar disorder.

Journal: CNS drugs 20120501

Title: Different safety profiles of risperidone and paliperidone extended-release: a double-blind, placebo-controlled trial with healthy volunteers.

Journal: Human psychopharmacology 20120501

Title: Effect of cytochrome P450 3A4 inhibitor ketoconazole on risperidone pharmacokinetics in healthy volunteers.

Journal: Journal of clinical pharmacy and therapeutics 20120401

Title: Relationship between dose, drug levels, and D2 receptor occupancy for the atypical antipsychotics risperidone and paliperidone.

Journal: The Journal of pharmacology and experimental therapeutics 20120401

Title: Practical guidelines on the use of paliperidone palmitate in schizophrenia.

Journal: Current medical research and opinion 20120401

Title: Predicting plasma concentration of risperidone associated with dosage change: a population pharmacokinetic study.

Journal: Therapeutic drug monitoring 20120401

Title: Catatonia and encephalopathy associated with paliperidone palmitate.

Journal: Journal of clinical psychopharmacology 20120401

Title: A stability-indicating ultra-performance liquid chromatographic method for estimation of related substances and degradants in paliperidone active pharmaceutical ingredient and its pharmaceutical dosage forms.

Journal: Journal of chromatographic science 20120401

Title: Prolongation of cardiac ventricular repolarization under paliperidone: how and how much?

Journal: Journal of cardiovascular pharmacology 20120301

Title: Publication bias in antipsychotic trials: an analysis of efficacy comparing the published literature to the US Food and Drug Administration database.

Journal: PLoS medicine 20120301

Title: Clinical pharmacology of paliperidone palmitate a parenteral long-acting formulation for the treatment of schizophrenia.

Journal: Reviews on recent clinical trials 20120201

Title: Acute renal failure after paliperidone overdose: a case report.

Journal: Journal of clinical psychopharmacology 20120201

Title: A change from risperidone long acting injection to paliperidone palmitate in an elderly patient--a cautionary tale.

Journal: The Australian and New Zealand journal of psychiatry 20120201

Title: Neurotoxic/neuroprotective activity of haloperidol, risperidone and paliperidone in neuroblastoma cells.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20120110

Title: Evaluation of the efficacy and safety of paliperidone extended-release in the treatment of acute mania: a randomized, double-blind, dose-response study.

Journal: Journal of affective disorders 20120101

Title: QT prolongation of the antipsychotic risperidone is predominantly related to its 9-hydroxy metabolite paliperidone.

Journal: Human psychopharmacology 20120101

Title: Oral-paliperidone-induced tardive dyskinesia: a case report.

Journal: General hospital psychiatry 20120101

Title: Anaphylactoid reaction to paliperidone palmitate extended-release injectable suspension in a patient tolerant of oral risperidone.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120101

Title: Effects of paliperidone extended release on the symptoms and functioning of schizophrenia.

Journal: BMC clinical pharmacology 20120101

Title: The threshold rate of oral atypical anti-psychotic adherence at which paliperidone palmitate is cost saving.

Journal: Journal of medical economics 20120101

Title: [Efficacy, tolerability and safety of paliperidone extended-release in the treatment of schizophrenia and schizoaffective disorder].

Journal: Rivista di psichiatria 20120101

Title: In situ nondestructive sediment characterization and resuspendability evaluation of concentrated aqueous paliperidone palmitate suspensions in prefilled syringes by low-field one-dimensional pulsed-field gradient NMR profilometry.

Journal: Pharmaceutical development and technology 20120101

Title: A one-year prospective study of the safety, tolerability and pharmacokinetics of the highest available dose of paliperidone palmitate in patients with schizophrenia.

Journal: BMC psychiatry 20120101

Title: Cost effectiveness of paliperidone palmitate versus risperidone long-acting injectable and olanzapine pamoate for the treatment of patients with schizophrenia in Sweden.

Journal: Journal of medical economics 20120101

Title: Health-related quality of life advantage of long-acting injectable antipsychotic treatment for schizophrenia: a time trade-off study.

Journal: Health and quality of life outcomes 20120101

Title: Genetic polymorphisms in CYP2E1: association with schizophrenia susceptibility and risperidone response in the Chinese Han population.

Journal: PloS one 20120101

Title: Treatment-completion rates with olanzapine long-acting injection versus risperidone long-acting injection in a 12-month, open-label treatment of schizophrenia: indirect, exploratory comparisons.

Journal: International journal of general medicine 20120101

Title: [Possibilities of the treatment of exacerbations of schizophrenia with the long acting atypical antipsychotic paliperidone palmitate].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20120101

Title: Effect of the cytochrome P450 2D6*10 allele on risperidone metabolism in Japanese psychiatric patients.

Journal: Human psychopharmacology 20120101

Title: Pharmacoeconomic analysis of paliperidone palmitate for treating schizophrenia in Greece.

Journal: Annals of general psychiatry 20120101

Title: Paliperidone palmitate injection for the acute and maintenance treatment of schizophrenia in adults.

Journal: Patient preference and adherence 20120101

Title: Management of antipsychotic treatment discontinuation and interruptions using model-based simulations.

Journal: Clinical pharmacology : advances and applications 20120101

Title: Treatment with paliperidone in children with behavior disorders previously treated with risperidone: an open-label trial.

Journal: Clinical neuropharmacology 20120101

Title: Long-term tolerability of once-monthly injectable paliperidone palmitate in subjects with recently diagnosed schizophrenia.

Journal: Neuropsychiatric disease and treatment 20120101

Title: Comparison of the peak-to-trough fluctuation in plasma concentration of long-acting injectable antipsychotics and their oral equivalents.

Journal: Innovations in clinical neuroscience 20120101

Title: Aripiprazole reverses paliperidone-induced hyperprolactinemia.

Journal: Actas espanolas de psiquiatria 20120101

Title: A randomized, double-blind study of paliperidone extended-release in treatment of acute schizophrenia in adolescents.

Journal: Biological psychiatry 20111215

Title: Social interaction and drug attitude effectiveness in patients with schizophrenia.

Journal: The Psychiatric quarterly 20111201

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: Neuroprotection of paliperidone on SH-SY5Y cells against β-amyloid peptide(25-35), N-methyl-4-phenylpyridinium ion, and hydrogen peroxide-induced cell death.

Journal: Psychopharmacology 20111001

Title: Effects of acute paliperidone palmitate treatment in subjects with schizophrenia recently treated with oral risperidone.

Journal: Schizophrenia research 20111001

Title: Comparing the influence of dopamine D₂ polymorphisms and plasma drug concentrations on the clinical response to risperidone.

Journal: Journal of clinical psychopharmacology 20111001

Title: Enantioselective fungal biotransformation of risperidone in liquid culture medium by capillary electrophoresis and hollow fiber liquid-phase microextraction.

Journal: Electrophoresis 20111001

Title: Dosing and switching strategies for paliperidone palmitate: based on population pharmacokinetic modelling and clinical trial data.

Journal: CNS drugs 20111001

Title: Paliperidone palmitate in a child with autistic disorder.

Journal: Journal of child and adolescent psychopharmacology 20111001

Title: Effects of risperidone and paliperidone pre-treatment on locomotor response following prenatal immune activation.

Journal: Journal of psychiatric research 20110901

Title: Influence of ABCB1 genetic polymorphisms on the pharmacokinetics of risperidone in healthy subjects with CYP2D6*10/*10.

Journal: British journal of pharmacology 20110901

Title: Effect of paliperidone and risperidone on extracellular glutamate in the prefrontal cortex of rats exposed to prenatal immune activation or MK-801.

Journal: Neuroscience letters 20110818

Title: The interaction of antipsychotic drugs with lipids and subsequent lipid reorganization investigated using biophysical methods.

Journal: Biochimica et biophysica acta 20110801

Title: Changes in schizophrenia-related hospitalization and ER use among patients receiving paliperidone palmitate: results from a clinical trial with a 52-week open-label extension (OLE).

Journal: Current medical research and opinion 20110801

Title: Osmotic-controlled release oral delivery system (OROS) paliperidone-related pruritic rash.

Journal: Journal of clinical psychopharmacology 20110801

Title: A Post-hoc comparison of paliperidone palmitate to oral risperidone during initiation of long-acting risperidone injection in patients with acute schizophrenia.

Journal: Innovations in clinical neuroscience 20110801

Title: Paliperidone overdose with delayed onset of toxicity.

Journal: Annals of emergency medicine 20110701

Title: Species independence in brain tissue binding using brain homogenates.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110701

Title: MultiSimplex optimization of chromatographic separation and dansyl derivatization conditions in the ultra performance liquid chromatography-tandem mass spectrometry analysis of risperidone, 9-hydroxyrisperidone, monoamine and amino acid neurotransmitters in human urine.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110701

Title: A comparative study of paliperidone palmitate and risperidone long-acting injectable therapy in schizophrenia.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20110601

Title: Prolongation of cardiac ventricular repolarization under paliperidone: how and how much?

Journal: Journal of cardiovascular pharmacology 20110601

Title: Risperidone in schizophrenia: is there a role for therapeutic drug monitoring?

Journal: Therapeutic drug monitoring 20110601

Title: Differential effects of antipsychotic medications on polyunsaturated fatty acid biosynthesis in rats: Relationship with liver delta6-desaturase expression.

Journal: Schizophrenia research 20110601

Title: Paliperidone-related rabbit syndrome.

Journal: Journal of clinical psychopharmacology 20110601

Title: Use of paliperidone in elderly patients with schizophrenia and schizoaffective disorder: a prospective open-label short-term pilot study.

Journal: Journal of clinical psychopharmacology 20110601

Title: Oral paliperidone: a review of its use in the management of schizoaffective disorder.

Journal: CNS drugs 20110601

Title: [Pharmacological properties of paliperidone ER (INVEGA(®)) and results of its clinical studies].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20110601

Title: A 52-week open-label study of the safety and tolerability of paliperidone palmitate in patients with schizophrenia.

Journal: Journal of psychopharmacology (Oxford, England) 20110501

Title: Lithium, but not fluoxetine or the corticotropin-releasing factor receptor 1 receptor antagonist R121919, increases cell proliferation in the adult dentate gyrus.

Journal: The Journal of pharmacology and experimental therapeutics 20110401

Title: Paliperidone augmentation for treatment-resistant depression: a case report.

Journal: Journal of clinical psychopharmacology 20110401

Title: Paliperidone-associated seizure after discontinuation of sodium valproate: a case report.

Journal: Journal of clinical psychopharmacology 20110401

Title: Predictors of risperidone and 9-hydroxyrisperidone serum concentration in children and adolescents.

Journal: Journal of child and adolescent psychopharmacology 20110401

Title: Risk of arrest in persons with schizophrenia and bipolar disorder in a Florida Medicaid program: the role of atypical antipsychotics, conventional neuroleptics, and routine outpatient behavioral health services.

Journal: The Journal of clinical psychiatry 20110401

Title: Paliperidone-associated atypical neuroleptic malignant syndrome: a case report.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20110330

Title: Paliperidone extended-release as adjunctive therapy to lithium or valproate in the treatment of acute mania: a randomized, placebo-controlled study.

Journal: Journal of affective disorders 20110301

Title: Are the long-acting intramuscular formulations of risperidone or paliperidone palmitate associated with post-injection delirium/sedation syndrome? An assessment of safety databases.

Journal: Current drug safety 20110201

Title: Change in employment status over 52 weeks in patients with schizophrenia: an observational study.

Journal: Current medical research and opinion 20110201

Title: Paliperidone-induced leukopenia and neutropenia: a case report.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20110115

Title: A double-blind study of paliperidone palmitate and risperidone long-acting injectable in adults with schizophrenia.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20110115

Title: Analysis of risperidone and 9-hydroxyrisperidone in human plasma, urine and saliva by MEPS-LC-UV.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110115

Title: Evaluation of the effect of paliperidone extended release and quetiapine on corrected QT intervals: a randomized, double-blind, placebo-controlled study.

Journal: International clinical psychopharmacology 20110101

Title: Paliperidone ER and oral risperidone in patients with schizophrenia: a comparative database analysis.

Journal: BMC psychiatry 20110101

Title: Paliperidone-induced neuroleptic malignant syndrome.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20110101

Title: Dose-associated changes in safety and efficacy parameters observed in a 24-week maintenance trial of olanzapine long-acting injection in patients with schizophrenia.

Journal: BMC psychiatry 20110101

Title: Cardiac safety of the electroconvulsive therapy-paliperidone combination: a preliminary study.

Journal: General hospital psychiatry 20110101

Title: Paliperidone extended-release: does it have a place in antipsychotic therapy?

Journal: Drug design, development and therapy 20110101

Title: Onset of efficacy with acute long-acting injectable paliperidone palmitate treatment in markedly to severely ill patients with schizophrenia: post hoc analysis of a randomized, double-blind clinical trial.

Journal: Annals of general psychiatry 20110101

Title: The use of videoconferencing with patients with psychosis: a review of the literature.

Journal: Annals of general psychiatry 20110101

Title: Number needed to treat and number needed to harm with paliperidone palmitate relative to long-acting haloperidol, bromperidol, and fluphenazine decanoate for treatment of patients with schizophrenia.

Journal: Neuropsychiatric disease and treatment 20110101

Title: Acute dystonia associated with paliperidone overdose.

Journal: Psychosomatics 20110101

Title: Onset of efficacy and tolerability following the initiation dosing of long-acting paliperidone palmitate: post-hoc analyses of a randomized, double-blind clinical trial.

Journal: BMC psychiatry 20110101

Title: Paliperidone-induced obsessive symptoms.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20110101

Title: Dose pattern and effectiveness of paliperidone extended-release tablets in patients with schizophrenia.

Journal: Clinical neuropharmacology 20110101

Title: An in vitro evaluation of guanfacine as a substrate for P-glycoprotein.

Journal: Neuropsychiatric disease and treatment 20110101

Title: The cost associated with administering risperidone long-acting injections in the Australian community.

Journal: BMC health services research 20110101

Title: Improvement of oral dyskinesia after switching from aripiprazole to paliperidone: a case report.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20110101

Title: Manic symptoms during a switch from risperidone to paliperidone: a case report.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20110101

Title: Clinical utility of the risperidone formulations in the management of schizophrenia.

Journal: Neuropsychiatric disease and treatment 20110101

Title: [Case of schizophrenia in which depressive and negative symptoms relapsed on switching from oral risperidone to risperidone long-acting injection].

Journal: Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 20110101

Title: Emergence of neuroleptic malignant syndrome while switching between risperidone and paliperidone.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20110101

Title: Tardive Tourette-like syndrome in a patient treated with paliperidone.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20110101

Title: Clozapine and other competitive antagonists reactivate risperidone-inactivated h5-HT7 receptors: radioligand binding and functional evidence for GPCR homodimer protomer interactions.

Journal: Psychopharmacology 20101201

Title: Effect of cyamemazine on the steady-state plasma concentrations of risperidone and 9-hydroxyrisperidone: a preliminary retrospective study.

Journal: Therapeutic drug monitoring 20101201

Title: Association of 9-hydroxy risperidone concentrations with risk of switching or discontinuation in the clinical antipsychotic trial of intervention effectiveness-Alzheimer's disease trial.

Journal: Journal of clinical psychopharmacology 20101201

Title: The role of CYP2D6 and ABCB1 pharmacogenetics in drug-naïve patients with first-episode schizophrenia treated with risperidone.

Journal: European journal of clinical pharmacology 20101101

Title: Tolerability of paliperidone: a meta-analysis of randomized, controlled trials.

Journal: International clinical psychopharmacology 20101101

Title: Armodafinil as adjunctive therapy in adults with cognitive deficits associated with schizophrenia: a 4-week, double-blind, placebo-controlled study.

Journal: The Journal of clinical psychiatry 20101101

Title: Relative bioavailability of two oral formulations of risperidone 2 mg: A single-dose, randomized-sequence, open-label, two-period crossover comparison in healthy Brazilian volunteers.

Journal: Clinical therapeutics 20101101

Title: A population pharmacokinetic evaluation of the influence of CYP2D6 genotype on risperidone metabolism in patients with acute episode of schizophrenia.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20101009

Title: Paliperidone-induced mania-like symptoms: a case report.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20101001

Title: Gender differences in the relationship between the risperidone metabolism and the plasma prolactin levels in psychiatric patients.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20101001

Title: Differential effects of antipsychotic and antidepressant drugs on neurogenic regions in rats.

Journal: Brain research 20101001

Title: Paliperidone extended-release in schizoaffective disorder: a randomized, controlled study comparing a flexible dose with placebo in patients treated with and without antidepressants and/or mood stabilizers.

Journal: Journal of clinical psychopharmacology 20101001

Title: Paliperidone extended-release: a review of efficacy and tolerability in schizophrenia, schizoaffective disorder and bipolar mania.

Journal: Expert opinion on pharmacotherapy 20101001

Title: Efficacy and safety of paliperidone palmitate in adult patients with acutely symptomatic schizophrenia: a randomized, double-blind, placebo-controlled, dose-response study.

Journal: International clinical psychopharmacology 20100901

Title: A controlled, evidence-based trial of paliperidone palmitate, a long-acting injectable antipsychotic, in schizophrenia.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100901

Title: New antipsychotic drugs: how do their receptor-binding profiles compare?

Journal: The Journal of clinical psychiatry 20100901

Title: [9-hydroxy-risperidone (9OHRIS) prevents stress-induced β-actin overexpression in rat hippocampus].

Journal: Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20100901

Title: Relative bioavailability and pharmacokinetic comparison of two 2-mg risperidone tablet formulations: A single dose, randomized-sequence, double-blind, 2-way crossover study in healthy male volunteers in Thailand.

Journal: Clinical therapeutics 20100901

Title: Using aripiprazole to attenuate paliperidone-induced hyperprolactinemia.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20100816

Title: [Efficacy of paliperidone extended-release tablets in the improvement of social functions in schizophrenics: a randomized and controlled study].

Journal: Zhonghua yi xue za zhi 20100803

Title: Serum concentrations of paliperidone versus risperidone and clinical effects.

Journal: European journal of clinical pharmacology 20100801

Title: Neuroleptic malignant syndrome secondary to aripiprazole initiation in a clozapine-intolerant patient.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100801

Title: Studies on the acute toxicity, pharmacokinetics and pharmacodynamics of paliperidone derivatives--comparison to paliperidone and risperidone in mice and rats.

Journal: Basic & clinical pharmacology & toxicology 20100801

Title: One-year open-label safety and efficacy study of paliperidone extended-release tablets in patients with schizophrenia.

Journal: CNS spectrums 20100801

Title: Paliperidone extended release: a review of its use in the management of schizophrenia.

Journal: Drugs 20100709

Title: Relationship between response to risperidone, plasma concentrations of risperidone and CYP3A4 polymorphisms in schizophrenia patients.

Journal: Journal of psychopharmacology (Oxford, England) 20100701

Title: Clinical response to risperidone in relation to plasma drug concentrations in acutely exacerbated schizophrenic patients.

Journal: Journal of psychopharmacology (Oxford, England) 20100701

Title: A comparison of serum prolactin concentrations after administration of paliperidone extended-release and risperidone tablets in patients with schizophrenia.

Journal: Journal of psychopharmacology (Oxford, England) 20100701

Title: Long-acting injectable risperidone and metabolic ratio: a possible index of clinical outcome in treatment-resistant schizophrenic patients.

Journal: Psychopharmacology 20100701

Title: Single-dose pharmacokinetics of paliperidone extended-release tablets in healthy Chinese subjects.

Journal: Human psychopharmacology 20100701

Title: Paliperidone palmitate injection: Its efficacy, safety and tolerability in schizophrenia.

Journal: Drugs of today (Barcelona, Spain : 1998) 20100701

Title: Paliperidone palmitate, a potential long-acting treatment for patients with schizophrenia. Results of a randomized, double-blind, placebo-controlled efficacy and safety study.

Journal: The international journal of neuropsychopharmacology 20100601

Title: Inconsistency in risperidone long-acting injection steady-state plasma levels when switching from deltoid to gluteal administration.

Journal: Journal of clinical pharmacology 20100601

Title: Effect of CYP2D6, CYP3A5, and MDR1 genetic polymorphisms on the pharmacokinetics of risperidone and its active moiety.

Journal: Journal of clinical pharmacology 20100601

Title: Personal and social functioning in schizophrenia: defining a clinically meaningful measure of maintenance in relapse prevention.

Journal: Current medical research and opinion 20100601

Title: Hyperprolactinaemia during treatment with paliperidone.

Journal: Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists 20100601

Title: A randomized, placebo-controlled study to assess the efficacy and safety of 3 doses of paliperidone palmitate in adults with acutely exacerbated schizophrenia.

Journal: Journal of clinical psychopharmacology 20100601

Title: Efficacy and tolerability of paliperidone ER and other oral atypical antipsychotics in schizophrenia.

Journal: International journal of clinical pharmacology and therapeutics 20100601

Title: Medication satisfaction in schizophrenia: a blinded-initiation study of paliperidone extended release in patients suboptimally responsive to risperidone.

Journal: International clinical psychopharmacology 20100501

Title: A randomized, double-blind, placebo-controlled study of 2 dose ranges of paliperidone extended-release in the treatment of subjects with schizoaffective disorder.

Journal: The Journal of clinical psychiatry 20100501

Title: A randomized, placebo- and active-controlled study of paliperidone extended release for the treatment of acute manic and mixed episodes of bipolar I disorder.

Journal: Bipolar disorders 20100501

Title: Efficacy and safety of atypical antipsychotic drugs (quetiapine, risperidone, aripiprazole and paliperidone) compared with placebo or typical antipsychotic drugs for treating refractory schizophrenia: overview of systematic reviews.

Journal: Sao Paulo medical journal = Revista paulista de medicina 20100501

Title: Paliperidone use in the elderly.

Journal: Current drug safety 20100401

Title: Manic symptoms induced by paliperidone.

Journal: Journal of clinical psychopharmacology 20100401

Title: Paliperidone overdose in a patient with schizophrenia.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20100317

Title: Effects of quetiapine, risperidone, 9-hydroxyrisperidone and ziprasidone on the survival of human neuronal and immune cells in vitro.

Journal: Journal of psychopharmacology (Oxford, England) 20100301

Title: A comparison of continuous subcutaneous paliperidone infusion and repeated subcutaneous injection of risperidone free-base in rats.

Journal: European psychiatry : the journal of the Association of European Psychiatrists 20100301

Title: Modeling the effectiveness of paliperidone ER and olanzapine in schizophrenia: meta-analysis of 3 randomized, controlled clinical trials.

Journal: Journal of clinical pharmacology 20100301

Title: Intramuscular paliperidone palmitate.

Journal: CNS drugs 20100301

Title: Remission of drug-induced hepatitis after switching from risperidone to paliperidone.

Journal: The American journal of psychiatry 20100301

Title: Serum concentrations, therapeutic response and side effects in children and adolescents with impulsive-aggressive symptoms during risperidone therapy.

Journal: Pharmacopsychiatry 20100301

Title: Paliperidone palmitate maintenance treatment in delaying the time-to-relapse in patients with schizophrenia: a randomized, double-blind, placebo-controlled study.

Journal: Schizophrenia research 20100201

Title: Practical guidance for dosing and switching paliperidone palmitate treatment in patients with schizophrenia.

Journal: Current medical research and opinion 20100201

Title: Possible neuroleptic malignant syndrome during paliperidone administration: a case report.

Journal: Journal of clinical psychopharmacology 20100201

Title: Paliperidone for irritability in autistic disorder.

Journal: Journal of child and adolescent psychopharmacology 20100201

Title: Paliperidone extended-release tablets in patients with recently diagnosed schizophrenia.

Journal: Early intervention in psychiatry 20100201

Title: Measuring social functioning with the personal and social performance scale in patients with acute symptoms of schizophrenia: interpretation of results of a pooled analysis of three Phase III trials of paliperidone extended-release tablets.

Journal: Clinical therapeutics 20100201

Title: Efficacy and safety of paliperidone extended-release in schizophrenia patients with prominent affective symptoms.

Journal: Journal of affective disorders 20100101

Title: Paliperidone palmitate - review of the efficacy, safety and cost of a new second-generation depot antipsychotic medication.

Journal: International journal of clinical practice 20100101

Title: The pharmacokinetics of paliperidone versus risperidone.

Journal: Psychosomatics 20100101

Title: Long-acting injectable antipsychotics: focus on olanzapine pamoate.

Journal: Neuropsychiatric disease and treatment 20100101

Title: Once-monthly paliperidone injection for the treatment of schizophrenia.

Journal: Neuropsychiatric disease and treatment 20100101

Title: Exploratory analysis of psychiatric-related utilization and costs associated with paliperidone ER compared with other oral atypical antipsychotics using pharmacy claims from an administrative database.

Journal: Journal of medical economics 20100101

Title: Role of paliperidone extended-release in treatment of schizoaffective disorder.

Journal: Neuropsychiatric disease and treatment 20100101

Title: Paliperidone-induced dystonic Dysphagia.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20100101

Title: [Non-fatal paliperidone overdose: a case report].

Journal: Turk psikiyatri dergisi = Turkish journal of psychiatry 20100101

Title: Simultaneous determination of risperidone and 9-hydroxyrisperidone enantiomers in human blood plasma by liquid chromatography with electrochemical detection.

Journal: Journal of pharmaceutical and biomedical analysis 20091205

Title: Impact of CYP2D6 genotype on steady-state serum concentrations of risperidone and 9-hydroxyrisperidone in patients using long-acting injectable risperidone.

Journal: Journal of clinical psychopharmacology 20091201

Title: [Successful quetiapine therapy in psychotic patients with mood elevation].

Journal: Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20091201

Title: In brief: Injectable paliperidone palmitate for schizophrenia.

Journal: The Medical letter on drugs and therapeutics 20091102

Title: Single- and multiple-dose pharmacokinetics and dose proportionality of the psychotropic agent paliperidone extended release.

Journal: Journal of clinical pharmacology 20091101

Title: Second-generation antipsychotic long-acting injections: systematic review.

Journal: The British journal of psychiatry. Supplement 20091101

Title: Effects of the antipsychotic risperidone on dopamine synthesis in human brain measured by positron emission tomography with L-[beta-11C]DOPA: a stabilizing effect for dopaminergic neurotransmission?

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20091028

Title: Paliperidone for treatment of obsessive compulsive resistant symptoms in schizophrenia: a case report.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20091001

Title: No pharmacokinetic interaction between paliperidone extended-release tablets and trimethoprim in healthy subjects.

Journal: Human psychopharmacology 20091001

Title: Independent effect of paliperidone extended release on social functioning beyond its effect on positive and negative symptoms of schizophrenia: a mediation analysis.

Journal: Journal of clinical psychopharmacology 20091001

Title: The influence of hepatic impairment on the pharmacokinetics of paliperidone.

Journal: International journal of clinical pharmacology and therapeutics 20091001

Title: Determination of risperidone and 9-Hydroxyrisperidone using HPLC, in plasma of children and adolescents with emotional and behavioural disorders.

Journal: Biomedical chromatography : BMC 20090901

Title: Human 5-HT7 receptor-induced inactivation of forskolin-stimulated adenylate cyclase by risperidone, 9-OH-risperidone and other 'inactivating antagonists'.

Journal: Molecular pharmacology 20090901

Title: Safety and tolerability of deltoid and gluteal injections of paliperidone palmitate in schizophrenia.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20090831

Title: Time resolved analysis of risperidone and 9-hydroxy-risperidone in hair using LC/MS-MS.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090815

Title: Pharmacokinetics and efficacy of a direct switch from conventional depot to risperidone long-acting injection in Chinese patients with schizophrenic and schizoaffective disorders.

Journal: Psychiatry and clinical neurosciences 20090801

Title: Serum levels of risperidone and its metabolite, 9-hydroxyrisperidone: correlation between drug concentration and clinical response.

Journal: Therapeutic drug monitoring 20090801

Title: Paliperidone extended-release for schizophrenia: effects on symptoms and functioning in acutely ill patients with negative symptoms.

Journal: Schizophrenia research 20090801

Title: Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers.

Journal: Journal of medicinal chemistry 20090723

Title: Impact of psychotic relapse definitions in assessing drug efficacy and costs: comparison of quetiapine XR, olanzapine and paliperidone ER.

Journal: Current medical research and opinion 20090701

Title: The effects of paroxetine on the pharmacokinetics of paliperidone extended-release tablets.

Journal: Pharmacopsychiatry 20090701

Title: Effects of the CYP2D6*10 alleles and co-medication with CYP2D6-dependent drugs on risperidone metabolism in patients with schizophrenia.

Journal: Human psychopharmacology 20090601

Title: Randomized, double-blind, placebo-controlled study of paliperidone extended-release and quetiapine in inpatients with recently exacerbated schizophrenia.

Journal: The American journal of psychiatry 20090601

Title: Effects of CYP2D6 and CYP3A5 genotypes on the plasma concentrations of risperidone and 9-hydroxyrisperidone in Korean schizophrenic patients.

Journal: Journal of clinical psychopharmacology 20090601

Title: In thrombin stimulated human platelets Citalopram, Promethazine, Risperidone, and Ziprasidone, but not Diazepam, may exert their pharmacological effects also through intercalation in membrane phospholipids in a receptor-independent manner.

Journal: Journal of chemical biology 20090601

Title: Paliperidone suppresses the development of the aggressive phenotype in a developmentally sensitive animal model of escalated aggression.

Journal: Psychopharmacology 20090501

Title: Secondary delusional parasitosis treated with paliperidone.

Journal: Clinical and experimental dermatology 20090401

Title: An agonist-antagonist interaction model for prolactin release following risperidone and paliperidone treatment.

Journal: Clinical pharmacology and therapeutics 20090401

Title: Sensitivity of older patients to antipsychotic motor side effects: a PET study examining potential mechanisms.

Journal: The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20090301

Title: Paliperidone in an adult patient with Asperger syndrome: case report.

Journal: Pharmacopsychiatry 20090301

Title: Expected clinical benefits of paliperidone extended-release formulation when compared with risperidone immediate-release.

Journal: Expert opinion on drug delivery 20090301

Title: Pharmacological analysis of the novel, rapid, and potent inactivation of the human 5-Hydroxytryptamine7 receptor by risperidone, 9-OH-Risperidone, and other inactivating antagonists.

Journal: Molecular pharmacology 20090201

Title: Reliability, validity and ability to detect change of the clinician-rated Personal and Social Performance scale in patients with acute symptoms of schizophrenia.

Journal: Current medical research and opinion 20090201

Title: Bioequivalence evaluation of two strengths of risperidone tablet formulations in healthy volunteers.

Journal: International journal of clinical pharmacology and therapeutics 20090201

Title: [Psychiatry].

Journal: Revue medicale suisse 20090114

Title: Population pharmacokinetics of intramuscular paliperidone palmitate in patients with schizophrenia: a novel once-monthly, long-acting formulation of an atypical antipsychotic.

Journal: Clinical pharmacokinetics 20090101

Title: Efficacy and safety of risperidone long-acting injection in elderly people with schizophrenia.

Journal: Clinical interventions in aging 20090101

Title: Paliperidon mediated modification of cortical inhibition.

Journal: Neuro endocrinology letters 20090101

Title: Antipsychotic induced catatonia: a case of probable dementia with Lewy bodies.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20090101

Title: Patient perspectives in the development and use of long-acting antipsychotics in schizophrenia: focus on olanzapine long-acting injection.

Journal: Patient preference and adherence 20090101

Title: [Treatment with paliperidone extended-release tablets in a case of resistant undifferentiated schizophrenia: clinical improvement with 12 mg and evaluation through 3TRE scale].

Journal: Rivista di psichiatria 20090101

Title: Study of the complexation of risperidone and 9-hydroxyrisperidone with cyclodextrin hosts using affinity capillary electrophoresis and (1)H NMR spectroscopy.

Journal: Journal of chromatography. A 20081226

Title: The disparity of pharmacokinetics and prolactin study for risperidone long-acting injection.

Journal: Journal of clinical psychopharmacology 20081201

Title: What are the nursing implications when using paliperidone prolonged release for people with schizophrenia.

Journal: Journal of psychiatric and mental health nursing 20081201

Title: Apparent seizure and atrial fibrillation associated with paliperidone.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20081115

Title: Population pharmacokinetic analysis for risperidone using highly sparse sampling measurements from the CATIE study.

Journal: British journal of clinical pharmacology 20081101

Title: Efficacy and safety of oral paliperidone extended-release tablets in the treatment of acute schizophrenia: pooled data from three 52-week open-label studies.

Journal: International clinical psychopharmacology 20081101

Title: Paliperidone as a mood stabilizer: a pre-frontal cortex synaptoneurosomal proteomics comparison with lithium and valproic acid after chronic treatment reveals similarities in protein expression.

Journal: Brain research 20081003

Title: ABCB1 polymorphisms influence steady-state plasma levels of 9-hydroxyrisperidone and risperidone active moiety.

Journal: Therapeutic drug monitoring 20081001

Title: Impact of multiple inhibitors or substrates of cytochrome P450 2D6 on plasma risperidone levels in patients on polypharmacy.

Journal: Therapeutic drug monitoring 20081001

Title: Paliperidone extended-release for the treatment of schizophrenia.

Journal: Pharmacotherapy 20081001

Title: Antipsychotic drugs inhibit the function of breast cancer resistance protein.

Journal: Basic & clinical pharmacology & toxicology 20081001

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20081001

Title: Risperidone long-acting injection: a review of its long term safety and efficacy.

Journal: Neuropsychiatric disease and treatment 20081001

Title: Direct and indirect effects of paliperidone extended-release tablets on negative symptoms of schizophrenia.

Journal: Neuropsychiatric disease and treatment 20081001

Title: Choreatic symptoms during and after treatment with paliperidone and escitalopram.

Journal: Pharmacopsychiatry 20080901

Title: [Paliperidone--a novel second-generation antipsychotic].

Journal: Ugeskrift for laeger 20080825

Title: Toward prediction of alkane/water partition coefficients.

Journal: Journal of medicinal chemistry 20080710

Title: Paliperidone extended-release tablets in schizophrenia patients previously treated with risperidone.

Journal: International clinical psychopharmacology 20080701

Title: Validated LC-MS/MS methods for the determination of risperidone and the enantiomers of 9-hydroxyrisperidone in human plasma and urine.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080701

Title: Metabolism of atypical antipsychotics: involvement of cytochrome p450 enzymes and relevance for drug-drug interactions.

Journal: Current drug metabolism 20080601

Title: Hospitalization rates before and after initiation of paliperidone ER in patients with schizophrenia: results from open-label extensions of the US double-blind trials.

Journal: Current medical research and opinion 20080601

Title: Paliperidone for treatment of schizophrenia.

Journal: Schizophrenia bulletin 20080501

Title: Efficacy and tolerability of oral paliperidone extended-release tablets in the treatment of acute schizophrenia: pooled data from three 6-week, placebo-controlled studies.

Journal: The Journal of clinical psychiatry 20080501

Title: Paliperidone for schizophrenia.

Journal: The Cochrane database of systematic reviews 20080416

Title: Pharmacodynamic consequences of P-glycoprotein-dependent pharmacokinetics of risperidone and haloperidol in mice.

Journal: Behavioural brain research 20080409

Title: Dose-finding study of paliperidone ER based on striatal and extrastriatal dopamine D2 receptor occupancy in patients with schizophrenia.

Journal: Psychopharmacology 20080401

Title: Absorption, metabolism, and excretion of paliperidone, a new monoaminergic antagonist, in humans.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080401

Title: New drug update: 2007.

Journal: The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20080401

Title: Paliperidone: An improvement over risperidone?

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080301

Title: Paliperidone for schizophrenia.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080301

Title: Relationship between prolactin secretion, and plasma risperidone and 9-hydroxyrisperidone concentrations in adolescents with schizophreniform disorder.

Journal: Psychoneuroendocrinology 20080201

Title: Paliperidone-ER: first atypical antipsychotic with oral extended release formulation.

Journal: Expert review of neurotherapeutics 20080201

Title: Paliperidone extended-release tablets for the acute and maintenance treatment of schizophrenia.

Journal: Clinical therapeutics 20080201

Title: Effect of rifampin, an inducer of CYP3A and P-glycoprotein, on the pharmacokinetics of risperidone.

Journal: Journal of clinical pharmacology 20080101

Title: Safety and tolerability of oral paliperidone extended-release tablets in elderly patients with schizophrenia: a double-blind, placebo-controlled study with six-month open-label extension.

Journal: The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20080101

Title: Long-term therapeutic drug monitoring of risperidone and olanzapine identifies altered steady-state pharmacokinetics: a clinical, two-group, naturalistic study.

Journal: Clinical drug investigation 20080101

Title: Gateways to clinical trials. July-August 2008.

Journal: Methods and findings in experimental and clinical pharmacology 20080101

Title: Upcoming agents for the treatment of schizophrenia: mechanism of action, efficacy and tolerability.

Journal: Drugs 20080101

Title: Efficacy and safety of paliperidone extended-release tablets: results of a 6-week, randomized, placebo-controlled study.

Journal: Biological psychiatry 20071215

Title: Paliperidone ER: a review of the clinical trial data.

Journal: Neuropsychiatric disease and treatment 20071201

Title: Serum prolactin levels, plasma risperidone levels, polymorphism of cytochrome P450 2D6 and clinical response in patients with schizophrenia.

Journal: Journal of psychopharmacology (Oxford, England) 20071101

Title: The pharmacology and safety of paliperidone extended-release in the treatment of schizophrenia.

Journal: Expert opinion on drug safety 20071101

Title: Sensitive liquid chromatography/tandem mass spectrometry method for the simultaneous determination of olanzapine, risperidone, 9-hydroxyrisperidone, clozapine, haloperidol and ziprasidone in rat brain tissue.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071015

Title: Paliperidone: a new extended-release oral atypical antipsychotic.

Journal: Expert opinion on pharmacotherapy 20071001

Title: Analytical and semipreparative enantioseparation of 9-hydroxyrisperidone, the main metabolite of risperidone, using high-performance liquid chromatography and capillary electrophoresis. Validation and determination of enantiomeric purity.

Journal: Journal of chromatography. A 20070907

Title: Distinct electrophysiological effects of paliperidone and risperidone on the firing activity of rat serotonin and norepinephrine neurons.

Journal: Psychopharmacology 20070901

Title: A double-blind, placebo-controlled, randomized study evaluating the effect of paliperidone extended-release tablets on sleep architecture in patients with schizophrenia.

Journal: International clinical psychopharmacology 20070901

Title: Enantioselective analysis of the antipsychotic 9-hydroxyrisperidone, main metabolite of risperidone, by chiral capillary EKC using dual CDs.

Journal: Electrophoresis 20070801

Title: Efficacy, safety and early response of paliperidone extended-release tablets (paliperidone ER): results of a 6-week, randomized, placebo-controlled study.

Journal: Schizophrenia research 20070701

Title: Limitations in discerning the effects of risperidone and its 9-hydroxy metabolite on prolactin levels in a small study of patients with schizophrenia.

Journal: Human psychopharmacology 20070701

Title: Plasma pharmacokinetic characteristics of risperidone and their relationship to saliva concentrations in children with psychiatric or neurodevelopmental disorders.

Journal: Clinical therapeutics 20070701

Title: Treatment with risperidone for 4 weeks increased plasma 3-methoxy-4-hydroxypnenylglycol (MHPG) levels, but did not alter plasma brain-derived neurotrophic factor (BDNF) levels in schizophrenic patients.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20070630

Title: Determination of risperidone and enantiomers of 9-hydroxyrisperidone in plasma by LC-MS/MS.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070601

Title: Pharmacokinetics study for hyperprolactinemia among schizophrenics switched from risperidone to risperidone long-acting injection.

Journal: Journal of clinical psychopharmacology 20070601

Title: [Development and identifiability analysis of parent-metabolite pharmacokinetic model for risperidone and its main active metabolite 9-hydroxyrisperidone].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20070601

Title: Molecule of the month. Paliperidone.

Journal: Drug news & perspectives 20070601

Title: Paliperidone extended-release tablets: a new atypical antipsychotic.

Journal: Journal of psychosocial nursing and mental health services 20070501

Title: A study of genetic (CYP2D6 and ABCB1) and environmental (drug inhibitors and inducers) variables that may influence plasma risperidone levels.

Journal: Pharmacopsychiatry 20070501

Title: Lack of bioequivalence between generic risperidone oral solution and originator risperidone tablets.

Journal: International journal of clinical pharmacology and therapeutics 20070501

Title: Risperidone and paliperidone inhibit p-glycoprotein activity in vitro.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070401

Title: Population pharmacokinetics of risperidone and 9-hydroxyrisperidone in patients with acute episodes associated with bipolar I disorder.

Journal: Journal of pharmacokinetics and pharmacodynamics 20070401

Title: Paliperidone: quo vadis?

Journal: International journal of clinical practice 20070401

Title: Extended-release paliperidone: efficacy, safety and tolerability profile of a new atypical antipsychotic.

Journal: Drugs of today (Barcelona, Spain : 1998) 20070401

Title: Paliperidone (Invega) for schizophrenia.

Journal: The Medical letter on drugs and therapeutics 20070312

Title: Treatment of schizophrenia with paliperidone extended-release tablets: a 6-week placebo-controlled trial.

Journal: Schizophrenia research 20070201

Title: Paliperidone extended-release tablets for prevention of symptom recurrence in patients with schizophrenia: a randomized, double-blind, placebo-controlled study.

Journal: Journal of clinical psychopharmacology 20070201

Title: Prolactin release in children treated with risperidone: impact and role of CYP2D6 metabolism.

Journal: Journal of clinical psychopharmacology 20070201

Title: FDA approves new antipsychotic.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070201

Title: Rapidly disintegrating risperidone in subjects with schizophrenia or schizoaffective disorder: a summary of ten phase I clinical trials assessing taste, tablet disintegration time, bioequivalence, and tolerability.

Journal: Clinical therapeutics 20070201

Title: Maintenance therapy with once-monthly administration of long-acting injectable risperidone in patients with schizophrenia or schizoaffective disorder: a pilot study of an extended dosing interval.

Journal: Annals of general psychiatry 20070101

Title: Valproic acid improves psychotic agitation without influencing plasma risperidone levels in schizophrenic patients.

Journal: Pharmacopsychiatry 20070101

Title: Effect of topiramate on plasma concentrations of clozapine, olanzapine, risperidone, and quetiapine in patients with psychotic disorders.

Journal: Clinical neuropharmacology 20070101

Title: Paliperidone extended release.

Journal: CNS drugs 20070101

Title: New drugs: paliperidone, dasatinib, and decitabine.

Journal: Journal of the American Pharmacists Association : JAPhA 20070101

Title: New drug for schizophrenia.

Journal: FDA consumer 20070101

Title: Possible neuroleptic malignant syndrome associated with paliperidone.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20070101

Title: Forty years of antipsychotic Drug research--from haloperidol to paliperidone--with Dr. Paul Janssen.

Journal: Arzneimittel-Forschung 20070101

Title: Paliperidone: the evidence of its therapeutic value in schizophrenia.

Journal: Core evidence 20070101

Title: Prolactin elevation of the antipsychotic risperidone is predominantly related to its 9-hydroxy metabolite.

Journal: Human psychopharmacology 20061201

Title: Effect of adjunctive lamotrigine treatment on the plasma concentrations of clozapine, risperidone and olanzapine in patients with schizophrenia or bipolar disorder.

Journal: Therapeutic drug monitoring 20061001

Title: Polymorphisms of the ABCB1 gene are associated with the therapeutic response to risperidone in Chinese schizophrenia patients.

Journal: Pharmacogenomics 20061001

Title: Evaluation of antipsychotic drugs as inhibitors of multidrug resistance transporter P-glycoprotein.

Journal: Psychopharmacology 20060901

Title: Membrane transporter proteins: a challenge for CNS drug development.

Journal: Dialogues in clinical neuroscience 20060901

Title: [Paliperidone].

Journal: Medizinische Monatsschrift fur Pharmazeuten 20060801

Title: Serum concentrations of risperidone and 9-OH risperidone following intramuscular injection of long-acting risperidone compared with oral risperidone medication.

Journal: Acta psychiatrica Scandinavica 20060701

Title: Positive modulation of glutamatergic receptors potentiates the suppressive effects of antipsychotics on conditioned avoidance responding in rats.

Journal: Pharmacology, biochemistry, and behavior 20060601

Title: Pharmacokinetics and bioequivalence evaluation of risperidone in healthy male subjects with different CYP2D6 genotypes.

Journal: Archives of pharmacal research 20060601

Title: [Trazodone for the treatment of behavioral and psychological symptoms of dementia (BPSD) in Alzheimer's disease: a retrospective study focused on the aggression and negativism in caregiving situations].

Journal: No to shinkei = Brain and nerve 20060601

Title: Risperidone in the treatment of bipolar mania.

Journal: Neuropsychiatric disease and treatment 20060601

Title: Optimization of the separation of some psychotropic drugs and their respective metabolites by liquid chromatography.

Journal: Journal of pharmaceutical and biomedical analysis 20060503

Title: Intestinal uptake and biodistribution of novel polymeric micelles after oral administration.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20060310

Title: Multiple dose pharmacokinetics of risperidone and 9-hydroxyrisperidone in Chinese female patients with schizophrenia.

Journal: Acta pharmacologica Sinica 20060301

Title: A PET study evaluating dopamine D2 receptor occupancy for long-acting injectable risperidone.

Journal: The American journal of psychiatry 20060301

Title: Liquid chromatography/tandem mass spectrometry method for simultaneous determination of risperidone and its active metabolite 9-hydroxyrisperidone in human plasma.

Journal: Rapid communications in mass spectrometry : RCM 20060101

Title: Dose-dependent interaction of paroxetine with risperidone in schizophrenic patients.

Journal: Journal of clinical psychopharmacology 20051201

Title: Plasma risperidone levels and clinical response in patients with first-episode psychosis.

Journal: Journal of clinical psychopharmacology 20051201

Title: Cytochrome P450 3A inhibitor itraconazole affects plasma concentrations of risperidone and 9-hydroxyrisperidone in schizophrenic patients.

Journal: Clinical pharmacology and therapeutics 20051101

Title: P-glycoprotein interaction with risperidone and 9-OH-risperidone studied in vitro, in knock-out mice and in drug-drug interaction experiments.

Journal: Human psychopharmacology 20051001

Title: Subtherapeutic risperidone serum concentrations in an adolescent during hemodialysis: a pharmacological puzzle.

Journal: Therapeutic drug monitoring 20051001

Title: Risperidone plasma levels, clinical response and side-effects.

Journal: European archives of psychiatry and clinical neuroscience 20050801

Title: Influence of age and gender on risperidone plasma concentrations.

Journal: Journal of psychopharmacology (Oxford, England) 20050701

Title: Effect of verapamil on pharmacokinetics and pharmacodynamics of risperidone: in vivo evidence of involvement of P-glycoprotein in risperidone disposition.

Journal: Clinical pharmacology and therapeutics 20050701

Title: Predominant role of the 9-hydroxy metabolite of risperidone in elevating blood prolactin levels.

Journal: The American journal of psychiatry 20050501

Title: Pharmacokinetics and D2 receptor occupancy of long-acting injectable risperidone (Risperdal Consta) in patients with schizophrenia.

Journal: The international journal of neuropsychopharmacology 20050301

Title: Risperidone and breast-feeding.

Journal: Journal of psychopharmacology (Oxford, England) 20050301

Title: Prediction of response to risperidone treatment with respect to plasma concencentrations of risperidone, catecholamine metabolites, and polymorphism of cytochrome P450 2D6.

Journal: International clinical psychopharmacology 20050301

Title: Serum concentrations of risperidone and 9-hydroxyrisperidone after administration of the long-acting injectable form of risperidone: evidence from a routine therapeutic drug monitoring service.

Journal: Therapeutic drug monitoring 20050201

Title: The impact of P-glycoprotein on the disposition of drugs targeted for indications of the central nervous system: evaluation using the MDR1A/1B knockout mouse model.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050101

Title: Pharmacokinetic profile of long-acting injectable risperidone at steady-state: comparison with oral administration.

Journal: L'Encephale 20050101

Title: The brain entry of risperidone and 9-hydroxyrisperidone is greatly limited by P-glycoprotein.

Journal: The international journal of neuropsychopharmacology 20041201

Title: Identification and characterization of major degradation products of risperidone in bulk drug and pharmaceutical dosage forms.

Journal: Journal of pharmaceutical and biomedical analysis 20040921

Title: A high-performance liquid chromatographic-atmospheric pressure chemical ionization-tandem mass spectrometric method for determination of risperidone and 9-hydroxyrisperidone in human plasma.

Journal: Journal of analytical toxicology 20040901

Title: Plasma risperidone concentrations during combined treatment with sertraline.

Journal: Therapeutic drug monitoring 20040801

Title: In vitro effects of risperidone and 9-hydroxy-risperidone on human platelet function, plasma coagulation, and fibrinolysis.

Journal: Clinical therapeutics 20040801

Title: QTc interval, CYP2D6 and CYP2C9 genotypes and risperidone plasma concentrations.

Journal: Journal of psychopharmacology (Oxford, England) 20040601

Title: Effects of various factors on steady-state plasma concentrations of risperidone and 9-hydroxyrisperidone: lack of impact of MDR-1 genotypes.

Journal: British journal of clinical pharmacology 20040501

Title: Correlation between scores on Continuous Performance Test and plasma concentration for schizophrenic patients on risperidone.

Journal: Psychiatry and clinical neurosciences 20040401

Title: Quantification of risperidone and 9-hydroxyrisperidone in plasma and saliva from adult and pediatric patients by liquid chromatography-mass spectrometry.

Journal: Journal of chromatography. A 20040213

Title: Transfer of risperidone and 9-hydroxyrisperidone into human milk.

Journal: The Annals of pharmacotherapy 20040201

Title: Risperidone treatment of children with autistic disorder: effectiveness, tolerability, and pharmacokinetic implications.

Journal: Journal of child and adolescent psychopharmacology 20040101

Title: Intra- and interindividual variations in steady-state plasma concentrations of risperidone and 9-hydroxyrisperidone in schizophrenic patients treated chronically with various doses of risperidone.

Journal: Therapeutic drug monitoring 20031201

Title: Effects of various CYP2D6 genotypes on the steady-state plasma concentrations of risperidone and its active metabolite, 9-hydroxyrisperidone, in Japanese patients with schizophrenia.

Journal: Therapeutic drug monitoring 20030601

Title: Pharmacokinetic comparison of fast-disintegrating and conventional tablet formulations of risperidone in healthy volunteers.

Journal: Clinical therapeutics 20030601

Title: Effects of risperidone on psychometric and cognitive functions in healthy elderly volunteers.

Journal: Psychopharmacology 20030201

Title: Effects of CYP2D6 genotypes on plasma concentrations of risperidone and enantiomers of 9-hydroxyrisperidone in Japanese patients with schizophrenia.

Journal: Journal of clinical pharmacology 20030201

Title: Validated method for the determination of risperidone and 9-hydroxyrisperidone in human plasma by liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030115

Title: Determination of risperidone and 9-hydroxyrisperidone in human plasma by liquid chromatography: application to the evaluation of CYP2D6 drug interactions.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030105

Title: Pharmacokinetic and safety assessments of galantamine and risperidone after the two drugs are administered alone and together.

Journal: Journal of clinical pharmacology 20021201

Title: Relationship between risperidone and 9-hydroxy-risperidone plasma concentrations and CYP2D6 enzyme activity in psychiatric patients.

Journal: Pharmacopsychiatry 20021101

Title: A colloidal graphite-coated emitter for sheathless capillary electrophoresis/nanoelectrospray ionization mass spectrometry.

Journal: Analytical chemistry 20021015

Title: Prediction and assessment of extrapyramidal side effects induced by risperidone based on dopamine D(2) receptor occupancy.

Journal: Synapse (New York, N.Y.) 20021001

Title: Simplified high-performance liquid chromatographic method for determination of risperidone and 9-hydroxyrisperidone in plasma after overdose.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020605

Title: Three-dimensional quantitative structure-activity relationship for inhibition of human ether-a-go-go-related gene potassium channel.

Journal: The Journal of pharmacology and experimental therapeutics 20020501

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: In vivo and in vitro myocardial binding of risperidone and 9-hydroxyrisperidone.

Journal: Toxicology and applied pharmacology 20020415

Title: The effect of fluoxetine on the pharmacokinetics and safety of risperidone in psychotic patients.

Journal: Pharmacopsychiatry 20020301

Title: Brain, plasma and tissue pharmacokinetics of risperidone and 9-hydroxyrisperidone after separate oral administration to rats.

Journal: Psychopharmacology 20020201

Title: Risperidone and 9-hydroxyrisperidone concentrations are not dependent on age or creatinine clearance among elderly subjects.

Journal: Journal of geriatric psychiatry and neurology 20020101

Title: Sequential changes in the plasma concentration of risperidone following intentional overdose.

Journal: Clinical neuropharmacology 20020101

Title: Different enantioselective 9-hydroxylation of risperidone by the two human CYP2D6 and CYP3A4 enzymes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20011001

Title: Plasma concentrations of risperidone and 9-hydroxyrisperidone during combined treatment with paroxetine.

Journal: Therapeutic drug monitoring 20010601

Title: Long-term treatment of chronic schizophrenia with risperidone: a study with plasma levels.

Journal: European psychiatry : the journal of the Association of European Psychiatrists 20010201

Title: Relationship between plasma risperidone and 9-hydroxyrisperidone concentrations and clinical response in patients with schizophrenia.

Journal: Psychopharmacology 20010101

Title: Effects of two atypical neuroleptics, olanzapine and risperidone, on the function of the urinary bladder and the external urethral sphincter in anesthetized rats.

Journal: BMC pharmacology 20010101

Title: Possible relationship between combined plasma concentrations of risperidone plus 9-hydroxyrisperidone and extrapyramidal symptoms. Preliminary study.

Journal: Neuropsychobiology 20010101

Title: Cytochrome P450 2D6 genotype and steady state plasma levels of risperidone and 9-hydroxyrisperidone.

Journal: Psychopharmacology 19991201

Title: Risperidone: a novel antipsychotic with balanced serotonin-dopamine antagonism, receptor occupancy profile, and pharmacologic activity.

Journal: The Journal of clinical psychiatry 19940501

Title: Mauri MC, Paletta S, Maffini M, et al. Clinical pharmacology of atypical antipsychotics: an update. EXCLI J. 2014;13:1163-1191. Published 2014 Oct 13.

Title: Peng L, et al. Paliperidone protects prefrontal cortical neurons from damages caused by MK-801 via Akt1/GSK3β signaling pathway. Schizophr Res. 2013 Jun;147(1):14-23.

Title: Yang MC, et al. Neuroprotection of paliperidone on SH-SY5Y cells against β-amyloid peptide(25-35), N-methyl-4-phenylpyridinium ion, and hydrogen peroxide-induced cell death. Psychopharmacology (Berl). 2011 Oct;217(3):397-410.

Title: Kalman S, et al. 9-hydroxy-risperidone (9OHRIS) prevents stress-induced β-actin overexpression in rat hippocampus. Neuropsychopharmacol Hung. 2010 Sep;12(3):425-31.

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Tags:144598-75-4 Molecular Formula|144598-75-4 MDL|144598-75-4 SMILES|144598-75-4 Paliperidone