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145-41-5,MFCD00066411
Catalog No.:AA001KCX

145-41-5 | Cholan-24-oic acid, 3,7,12-trioxo-, sodium salt, (5β)-

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1g
98%
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$200.00   $140.00
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5g
98%
in stock  
$629.00   $440.00
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25g
98%
in stock  
$1,843.00   $1,290.00
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100g
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$5,057.00   $3,540.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA001KCX
Chemical Name:
Cholan-24-oic acid, 3,7,12-trioxo-, sodium salt, (5β)-
CAS Number:
145-41-5
Molecular Formula:
C24H33NaO5
Molecular Weight:
424.5056
MDL Number:
MFCD00066411
SMILES:
[O-]C(=O)CC[C@H]([C@H]1CC[C@@H]2[C@]1(C)C(=O)C[C@H]1[C@H]2C(=O)C[C@H]2[C@]1(C)CCC(=O)C2)C.[Na+]
Properties
Properties
 
Form:
Solid  
MP:
>236°C (dec.)  
Storage:
Keep in dry area;-20 ℃;Inert atmosphere;  

Computed Properties
 
Complexity:
763  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
8  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
5  
Rotatable Bond Count:
4  

Literature

Title: Novel whole-cell biocatalysts with recombinant hydroxysteroid dehydrogenases for the asymmetric reduction of dehydrocholic acid.

Journal: Applied microbiology and biotechnology 20120901

Title: Biophysical investigations into the interactions of endotoxins with bile acids.

Journal: Innate immunity 20120401

Title: Preparation and characterization of uniform drug particles: dehydrocholic acid.

Journal: Journal of colloid and interface science 20120215

Title: Improvement of oxaprozin solubility and permeability by the combined use of cyclodextrin, chitosan, and bile components.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20110801

Title: Ursodeoxycholic acid is conjugated with taurine to promote secretin-stimulated biliary hydrocholeresis in the normal rat.

Journal: PloS one 20110101

Title: Thermodynamic and elastic fluctuation analysis of Langmuir mixed monolayers composed by dehydrocholic acid (HDHC) and didodecyldimethylammonium bromide (DDAB).

Journal: Colloids and surfaces. B, Biointerfaces 20100101

Title: Surgical outcome in relation to duct size at the porta hepatis and the use of cholagogues in patients with biliary atresia.

Journal: Tropical gastroenterology : official journal of the Digestive Diseases Foundation 20100101

Title: Spread mixed monolayers of deoxycholic and dehydrocholic acids at the air-water interface, effect of subphase pH. Characterization by axisymmetric drop shape analysis.

Journal: Biophysical chemistry 20080101

Title: Magnetic resonance cholangiopancreatography: potential usefulness of dehydrocholic acid (DHCA) administration in the evaluation of anastomotic site.

Journal: Hepato-gastroenterology 20080101

Title: Magnetic resonance cholangiopancreatography: potential usefulness of dehydrocholic acid (DHCA) administration in the evaluation of biliary disease.

Journal: Hepato-gastroenterology 20080101

Title: A new approach for diagnosis of hepatolithiasis: magnetic resonance cholangiopancreatography: potential usefulness of dehydrocholic acid (DHCA) administration in the evaluation of hepatolithiasis.

Journal: Hepato-gastroenterology 20080101

Title: Aqueous sodium dehydrocholate-sodium deoxycholate mixtures at low concentration.

Journal: Journal of colloid and interface science 20071015

Title: Determination of critical micellar concentrations of cholic acid and its keto derivatives.

Journal: Colloids and surfaces. B, Biointerfaces 20071001

Title: Regio- and stereoselective reductions of dehydrocholic acid.

Journal: Steroids 20060601

Title: A novel insulin derivative chemically modified with dehydrocholic acid: synthesis, characterization and biological activity.

Journal: Biotechnology and applied biochemistry 20050801

Title: Lasting blood-brain barrier disruption induces epileptic focus in the rat somatosensory cortex.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040908

Title: Spasmocanulase in irritable bowel syndrome.

Journal: Saudi medical journal 20020901

Title: Choledocholithiasis in an infant of extremely low birthweight.

Journal: Journal of paediatrics and child health 20020401

Title: Estradiol-17 beta-D-glucuronide (E-17G) cholestasis in perfused rat liver: fate of E-17G and choleretic responses to bile salts.

Journal: Hepatology (Baltimore, Md.) 19900501

Title: 3 beta-Hydroxysteroid dehydrogenase of Ruminococcus sp. from human intestinal bacteria.

Journal: Journal of biochemistry 19860501

Title: Cholestasis induced by estradiol-17 beta-D-glucuronide: mechanisms and prevention by sodium taurocholate.

Journal: Hepatology (Baltimore, Md.) 19840101

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Tags:145-41-5 Molecular Formula|145-41-5 MDL|145-41-5 SMILES|145-41-5 Cholan-24-oic acid, 3,7,12-trioxo-, sodium salt, (5β)-