+1 858-523-8231
Login | Register
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
Home Other Building Blocks 145667-75-0
145667-75-0,MFCD05865275
Catalog No.:AA001D70

145667-75-0 | (3aR,4R,5R,6aS)-5-Hydroxy-4-((R)-3-hydroxy-5-phenylpentyl)hexahydro-2H-cyclopenta[b]furan-2-one

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
≥98%
in stock  
$162.00   $113.00
- +
50mg
≥98%
in stock  
$719.00   $503.00
- +
100mg
≥98%
in stock  
$1,278.00   $894.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA001D70
Chemical Name:
(3aR,4R,5R,6aS)-5-Hydroxy-4-((R)-3-hydroxy-5-phenylpentyl)hexahydro-2H-cyclopenta[b]furan-2-one
CAS Number:
145667-75-0
Molecular Formula:
C18H24O4
Molecular Weight:
304.3808
MDL Number:
MFCD05865275
SMILES:
O[C@@H](CCc1ccccc1)CC[C@H]1[C@H](O)C[C@H]2[C@@H]1CC(=O)O2
Properties
Computed Properties
 
Complexity:
377  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
6  
XLogP3:
2.3  

Downstream Synthesis Route

[1]JournalofMedicinalChemistry,1993,vol.36,p.243-248

[1]CurrentPatentAssignee:CHIROGATEINTERNATIONAL,INC.-EP2837621,2015,A1

[2]CurrentPatentAssignee:CHIROGATEINTERNATIONAL,INC.-US2015/51410,2015,A1

[3]Zhu,Kejie;Hu,Sha;Liu,Minjie;Peng,Haihui;Chen,Fen-Er[AngewandteChemie-InternationalEdition,2019,vol.58,#29,p.9923-9927][Angew.Chem.,2019,vol.131,#29,p.10028-10032,5]

[4]Sasane,SachinA.;Bhise,NanduB.;Singh,GirijP.;Joseph,Alex;Shenoy,GauthamG.[SyntheticCommunications,2019,vol.49,#18,p.2350-2356]

[5]Hayashi,Yujiro;Umekubo,Nariyoshi[EuropeanJournalofOrganicChemistry,2020,vol.2020,#39,p.6221-6227]

Literature

Title: Pauly A, et al. In vitro and in vivo comparative toxicological study of a new preservative-free latanoprost formulation. Invest Ophthalmol Vis Sci. 2012 Dec 13;53(13):8172-80.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 145667-75-0
73252-09-2

73252-09-2

 113527-39-2

113527-39-2

 25379-26-4

25379-26-4
Building Blocks
More >
Tags:145667-75-0 Molecular Formula|145667-75-0 MDL|145667-75-0 SMILES|145667-75-0 (3aR,4R,5R,6aS)-5-Hydroxy-4-((R)-3-hydroxy-5-phenylpentyl)hexahydro-2H-cyclopenta[b]furan-2-one