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146670-40-8,MFCD00864137
Catalog No.:AA001E4V

146670-40-8 | Benzoic acid, 4-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1,3-dioxolan-2-yl]-

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5mg
≥98%(HPLC)
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$463.00   $324.00
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10mg
≥98%(HPLC)
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$675.00   $473.00
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25mg
≥98%(HPLC)
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$1,295.00   $907.00
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50mg
≥98%(HPLC)
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$1,913.00   $1,339.00
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100mg
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA001E4V
Chemical Name:
Benzoic acid, 4-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1,3-dioxolan-2-yl]-
CAS Number:
146670-40-8
Molecular Formula:
C24H28O4
Molecular Weight:
380.4767
MDL Number:
MFCD00864137
SMILES:
OC(=O)c1ccc(cc1)C1(OCCO1)c1ccc2c(c1)C(C)(C)CCC2(C)C
Properties
Computed Properties
 
Complexity:
581  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
XLogP3:
5.5  

Literature

Title: Retinoids and rexinoids inhibit hepatitis C virus independently of retinoid receptor signaling.

Journal: Microbes and infection 20140201

Title: Retinoid X receptor agonists inhibit phorbol-12-myristate-13-acetate (PMA)-induced differentiation of monocytic THP-1 cells into macrophages.

Journal: Molecular and cellular biochemistry 20100201

Title: Silicon analogues of the RXR-selective retinoid agonist SR11237 (BMS649): chemistry and biology.

Journal: ChemMedChem 20090701

Title: [Effect of retinoid X receptor activation on oxidized low-density lipoprotein induced cell differentiation of murine macrophage cell line into dendritic like cells].

Journal: Zhonghua xin xue guan bing za zhi 20070901

Title: Specificity of receptor-ligand interactions and their effect on dimerisation as observed by electrospray mass spectrometry: bile acids form stable adducts to the RXRalpha.

Journal: Journal of mass spectrometry : JMS 20051101

Title: Structure-activity relationships of methylene or terminal side chain modified retinoids on the differentiation and cell death signaling in NB4 promyelocytic leukemia cells.

Journal: Bioorganic & medicinal chemistry letters 20040816

Title: Regulation of retinoic acid receptor beta expression by peroxisome proliferator-activated receptor gamma ligands in cancer cells.

Journal: Cancer research 20030701

Title: Nicotine modulates the effects of retinoids on growth inhibition and RAR beta expression in lung cancer cells.

Journal: International journal of cancer 20020510

Title: Detection of a receptor-ligand non-covalent complex using a triple quadrupole mass spectrometer.

Journal: Rapid communications in mass spectrometry : RCM 20020101

Title: Differentiation of myeloid cell lines correlates with a selective expression of RIZ protein.

Journal: Molecular medicine (Cambridge, Mass.) 20010801

Title: Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains.

Journal: Molecular cell 20000201

Title: Retinoids selective for retinoid X receptor response pathways.

Journal: Science (New York, N.Y.) 19921218

Title: Gendimenico GJ, et al. A pleiotropic response is induced in F9 embryonal carcinoma cells and rhino mouse skin by All-trans-retinoic acid, a RAR agonist but not by SR11237, a RXR-selective agonist. J Invest Dermatol. 1994;102(5):676-680.

Title: Dupuis H, et al. Exposure to the RXR Agonist SR11237 in Early Life Causes Disturbed Skeletal Morphogenesis in a Rat Model. Int J Mol Sci. 2019;20(20):5198. Published 2019 Oct 20.

Title: H.L. Dupuis. The RXR agonist SR-11237 affects skeletal development. ABSTRACT ONLY| VOLUME 24, SUPPLEMENT 1, S147, APRIL 01, 2016.

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Tags:146670-40-8 Molecular Formula|146670-40-8 MDL|146670-40-8 SMILES|146670-40-8 Benzoic acid, 4-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1,3-dioxolan-2-yl]-