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146709-78-6,MFCD00921888
Catalog No.:AA001E66

146709-78-6 | ZD 7155 hydrochloride

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Purity
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Price(USD)
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1mg
≥98%
in stock  
$42.00   $29.00
- +
5mg
≥98%
in stock  
$142.00   $99.00
- +
10mg
≥98%
in stock  
$263.00   $184.00
- +
100mg
97%
in stock  
$314.00   $220.00
- +
  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA001E66
Chemical Name:
ZD 7155 hydrochloride
CAS Number:
146709-78-6
Molecular Formula:
C26H27ClN6O
Molecular Weight:
474.9852
MDL Number:
MFCD00921888
SMILES:
CCc1nc(CC)c2c(c1)N(Cc1ccc(cc1)c1ccccc1c1n[nH]nn1)C(=O)CC2.Cl
Properties
Computed Properties
 
Complexity:
653  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
6  

Literature

Title: Nitric oxide and angiotensin II regulate cardiovascular homeostasis and the arterial baroreflex control of heart rate in conscious lambs.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20120301

Title: Cardiovascular responses elicited by a new endogenous angiotensin in the nucleus tractus solitarius of the rat.

Journal: American journal of physiology. Heart and circulatory physiology 20110101

Title: Location of prorenin receptors in primate substantia nigra: effects on dopaminergic cell death.

Journal: Journal of neuropathology and experimental neurology 20101101

Title: Importance of angiotensinergic mechanisms for the pressor response to l-glutamate into the rostral ventrolateral medulla.

Journal: Brain research 20100331

Title: Acute modulation of myocardial function by angiotensin 1-7.

Journal: Peptides 20090901

Title: Angiotensin II enhances the afferent arteriolar response to adenosine through increases in cytosolic calcium.

Journal: Acta physiologica (Oxford, England) 20090801

Title: Angiotensin II regulates the activity of mouse suprachiasmatic nuclei neurons.

Journal: Neuroscience 20080623

Title: Cardiovascular responses and neurotransmitter changes during blockade of angiotensin II receptors within the ventrolateral medulla.

Journal: Neuroscience research 20080301

Title: Negative inotropic effect of selective AT2 receptor stimulation and its modulation by the endocardial endothelium.

Journal: European journal of pharmacology 20080114

Title: Angiotensin type-1-receptor antagonists reduce 6-hydroxydopamine toxicity for dopaminergic neurons.

Journal: Neurobiology of aging 20070401

Title: Angiotensin II acutely decreases myocardial stiffness: a novel AT1, PKC and Na+/H+ exchanger-mediated effect.

Journal: British journal of pharmacology 20060301

Title: Nitric oxide contributes to AT2 but not AT1 angiotensin II receptor-mediated vasodilatation of porcine pial arteries and arterioles.

Journal: European journal of pharmacology 20051121

Title: Angiotensin II and interleukin-1 interact to increase generation of dopaminergic neurons from neurospheres of mesencephalic precursors.

Journal: Brain research. Developmental brain research 20050808

Title: Regional hemodynamic effects of the N-(2-benzoylphenyl)-L-tyrosine peroxisome proliferator-activated receptor-gamma ligand, GI 262570 [(S)-2-(2-benzoylphenylamino)-3-[4-[2-(5-methyl-2-phenyl-2-oxazol-4-yl)ethoxy]phenyl]propionic acid], in conscious rats.

Journal: The Journal of pharmacology and experimental therapeutics 20040901

Title: Angiotensin II increases differentiation of dopaminergic neurons from mesencephalic precursors via angiotensin type 2 receptors.

Journal: The European journal of neuroscience 20040901

Title: Involvement of the renin-angiotensin system in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20040301

Title: Comparative cardiovascular effects of the angiotensin II type 1 receptor antagonists ZD 7155 and losartan in the rat.

Journal: The Journal of pharmacy and pharmacology 19960801

Title: Junggren IL, et al. Comparative cardiovascular effects of the angiotensin II type 1 receptor antagonists ZD 7155 and losartan in the rat. J Pharm Pharmacol. 1996 Aug;48(8):829-33.

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