[1]CurrentPatentAssignee:SUZHOUKAIRUIMEDICINESCIENCETECHNOLOGY-CN104072407,2016,B
[1]CurrentPatentAssignee:SUZHOUKAIRUIMEDICINESCIENCETECHNOLOGY-CN104072407,2016,B
[1]CurrentPatentAssignee:SUZHOUKAIRUIMEDICINESCIENCETECHNOLOGY-CN104072407,2016,BLocationinpatent:Paragraph0045
[1]CurrentPatentAssignee:SUZHOUKAIRUIMEDICINESCIENCETECHNOLOGY-CN104072407,2016,B
[1]CurrentPatentAssignee:SUZHOUKAIRUIMEDICINESCIENCETECHNOLOGY-CN104072407,2016,B
Title: Raf-1/CK2 and RhoA/ROCK signaling promote TNF-α-mediated endothelial apoptosis via regulating vimentin cytoskeleton.
Journal: Toxicology 20170815
Title: Polydatin prevents hypertrophy in phenylephrine induced neonatal mouse cardiomyocytes and pressure-overload mouse models.
Journal: European journal of pharmacology 20150105
Title: The role of Rho-kinases in IL-1β release through phagocytosis of fibrous particles in human monocytes.
Journal: Archives of toxicology 20150101
Title: ROCK-dependent ATP5D modulation contributes to the protection of notoginsenoside NR1 against ischemia-reperfusion-induced myocardial injury.
Journal: American journal of physiology. Heart and circulatory physiology 20141215
Title: The role of RhoA and cytoskeleton in myofibroblast transformation in hyperoxic lung fibrosis.
Journal: Free radical biology & medicine 20130801
Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.
Journal: Bioorganic & medicinal chemistry letters 20130801
Title: Optimization of novel nipecotic bis(amide) inhibitors of the Rho/MKL1/SRF transcriptional pathway as potential anti-metastasis agents.
Journal: Bioorganic & medicinal chemistry letters 20130701
Title: Activation of RhoA/ROCK regulates NF-κB signaling pathway in experimental diabetic nephropathy.
Journal: Molecular and cellular endocrinology 20130430
Title: A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
Journal: The Biochemical journal 20130415
Title: RhoGEF17, a Rho-specific guanine nucleotide exchange factor activated by phosphorylation via cyclic GMP-dependent kinase Iα.
Journal: Cellular signalling 20130301
Title: Erythropoietin promotes axonal regeneration after optic nerve crush in vivo by inhibition of RhoA/ROCK signaling pathway.
Journal: Neuropharmacology 20121101
Title: miRNAs can increase the efficiency of ex vivo platelet generation.
Journal: Annals of hematology 20121101
Title: The effect of hypercholesterolemia on carbachol-induced contractions of the detrusor smooth muscle in rats: increased role of L-type Ca2+ channels.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20121101
Title: High glucose enhances responsiveness of human airways smooth muscle via the Rho/ROCK pathway.
Journal: American journal of respiratory cell and molecular biology 20121001
Title: Cyclic compression-induced p38 activation and subsequent MMP13 expression requires Rho/ROCK activity in bovine cartilage explants.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20121001
Title: Bioengineered human IAS reconstructs with functional and molecular properties similar to intact IAS.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20120915
Title: Critical roles of Rho-associated kinase in membrane blebbing and mitochondrial pathway of apoptosis caused by 1-butanol.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20120901
Title: Stimulation of norepinephrine transporter function by fasudil, a Rho kinase inhibitor, in cultured bovine adrenal medullary cells.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20120901
Title: Aging impairs Ca2+ sensitization pathways in gallbladder smooth muscle.
Journal: Age (Dordrecht, Netherlands) 20120801
Title: Cells lacking β-actin are genetically reprogrammed and maintain conditional migratory capacity.
Journal: Molecular & cellular proteomics : MCP 20120801
Title: Soluble epoxide hydrolase: sex differences and role in endothelial cell survival.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20120801
Title: ROCK1 feedback regulation of the upstream small GTPase RhoA.
Journal: Cellular signalling 20120701
Title: Atorvastatin inhibits myocardin expression in vascular smooth muscle cells.
Journal: Hypertension (Dallas, Tex. : 1979) 20120701
Title: Arsenite activates NFκB through induction of C-reactive protein.
Journal: Toxicology and applied pharmacology 20120615
Title: Pregnancy reduces RhoA/Rho kinase and protein kinase C signaling pathways downstream of thromboxane receptor activation in the rat uterine artery.
Journal: American journal of physiology. Heart and circulatory physiology 20120615
Title: The role of Rho/Rho-kinase pathway in the expression of ICAM-1 by linoleic acid in human aortic endothelial cells.
Journal: Inflammation 20120601
Title: Possible Involvement of Sphingosine-1-Phosphate/G(i)/RhoA pathways in adherence of eosinophils to pulmonary endothelium.
Journal: Allergology international : official journal of the Japanese Society of Allergology 20120601
Title: Simvastatin attenuated cerebrovascular cell proliferation in the development of hypertension through Rho/Rho-kinase pathway.
Journal: Journal of cardiovascular pharmacology 20120601
Title: Role of sphingosine-1-phosphate inβ-adrenoceptor desensitization via Ca(2+) sensitization in airway smooth muscle.
Journal: Allergology international : official journal of the Japanese Society of Allergology 20120601
Title: Pyridylthiazole-based ureas as inhibitors of Rho associated protein kinases (ROCK1 and 2).
Journal: MedChemComm 20120601
Title: The effect of Rho-associated protein kinase inhibitor on monkey Schlemm's canal endothelial cells.
Journal: Investigative ophthalmology & visual science 20120522
Title: Thrombin receptor regulates hematopoiesis and endothelial-to-hematopoietic transition.
Journal: Developmental cell 20120515
Title: Perspective on the role of P2X-purinoceptor activation in human vas deferens contractility.
Journal: Experimental physiology 20120501
Title: Rho kinase (ROK)-related proteins in human cavernous arteries: an immunohistochemical and functional approach.
Journal: The journal of sexual medicine 20120501
Title: The Rho kinase inhibitor SAR407899 potently inhibits endothelin-1-induced constriction of renal resistance arteries.
Journal: Journal of hypertension 20120501
Title: Functional role of muscarinic receptor subtypes in calcium sensitization and their contribution to rho-kinase and protein kinase C pathways in contraction of human detrusor smooth muscle.
Journal: Urology 20120501
Title: ROCKII Ser1366 phosphorylation reflects the activation status.
Journal: The Biochemical journal 20120401
Title: Obstruction enhances rho-kinase pathway and diminishes protein kinase C pathway in carbachol-induced calcium sensitization in contraction of α-toxin permeabilized guinea pig detrusor smooth muscle.
Journal: Neurourology and urodynamics 20120401
Title: Inhibition of actin dynamics during epithelial-to-mesenchymal transition.
Journal: Biochemical and biophysical research communications 20120309
Title: Astrocyte stellation, a process dependent on Rac1 is sustained by the regulated exocytosis of enlargeosomes.
Journal: Glia 20120301
Title: GEF-H1/RhoA signalling pathway mediates lipopolysaccharide-induced intercellular adhesion molecular-1 expression in endothelial cells via activation of p38 and NF-κB.
Journal: Cytokine 20120301
Title: Simvastatin inhibits sphingosylphosphorylcholine-induced differentiation of human mesenchymal stem cells into smooth muscle cells.
Journal: Experimental & molecular medicine 20120227
Title: Progesterone enhances vascular endothelial cell migration via activation of focal adhesion kinase.
Journal: Journal of cellular and molecular medicine 20120201
Title: Regulatable stiffness in relaxed airway smooth muscle: a target for asthma treatment?
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20120201
Title: Gene pathway analysis of the mechanism by which the Rho-associated kinase inhibitor Y-27632 inhibits apoptosis in isolated thawed human embryonic stem cells.
Journal: Cryobiology 20120201
Title: Inhibition of Rho kinase by hydroxyfasudil attenuates brain edema after subarachnoid hemorrhage in rats.
Journal: Neurochemistry international 20120201
Title: Enucleation of human erythroblasts involves non-muscle myosin IIB.
Journal: Blood 20120126
Title: A role for mDia, a Rho-regulated actin nucleator, in tangential migration of interneuron precursors.
Journal: Nature neuroscience 20120115
Title: Accelerated generation of human induced pluripotent stem cells with retroviral transduction and chemical inhibitors under physiological hypoxia.
Journal: Biochemical and biophysical research communications 20120113
Title: Resolving the challenge of measuring ligand binding to membrane proteins by combining analytical ultracentrifugation and light scattering photometry.
Journal: Journal of pharmaceutical sciences 20120101
Title: Inhibition of phosphoinositide 3-kinase potentiates relaxation of porcine coronary arteries induced by nitroglycerin by decreasing phosphodiesterase type 5 activity.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101
Title: A possible mechanism of basic fibroblast growth factor-promoted scarless wound healing: the induction of myofibroblast apoptosis.
Journal: European journal of dermatology : EJD 20120101
Title: Effect of simvastatin on transforming growth factor beta-1-induced myofibroblast differentiation and collagen production in nasal polyp-derived fibroblasts.
Journal: American journal of rhinology & allergy 20120101
Title: RhoA: a therapeutic target for chronic myeloid leukemia.
Journal: Molecular cancer 20120101
Title: Impaired myogenic tone in isolated cerebral and coronary resistance arteries from the goto-kakizaki rat model of type 2 diabetes.
Journal: Journal of vascular research 20120101
Title: [Y-27632 induces calcium-independent glutamate release in rat brain synaptosomes by the mechanism which is distinct from exocytosis].
Journal: Biofizika 20120101
Title: Different effect of Rho kinase inhibition on calcium signaling in rat isolated large and small arteries.
Journal: Journal of vascular research 20120101
Title: RhoA-ROCK-Myosin pathway regulates morphological plasticity of cultured olfactory ensheathing cells.
Journal: Experimental cell research 20111210
Title: Protective effects of dexpanthenol and y-27632 on stricture formation in a rat model of caustic esophageal injury.
Journal: The Journal of surgical research 20111201
Title: The suppression of myosin light chain (MLC) phosphorylation during the response to lipopolysaccharide (LPS): beneficial or detrimental to endothelial barrier?
Journal: Journal of cellular physiology 20111201
Title: Synthetic osteogenic growth peptide promotes differentiation of human bone marrow mesenchymal stem cells to osteoblasts via RhoA/ROCK pathway.
Journal: Molecular and cellular biochemistry 20111201
Title: Differential involvement of ezrin/radixin/moesin proteins in sphingosine 1-phosphate-induced human pulmonary endothelial cell barrier enhancement.
Journal: Cellular signalling 20111201
Title: Depigmenting action of platycodin D depends on the cAMP/Rho-dependent signalling pathway.
Journal: Experimental dermatology 20111201
Title: Wnt-signaling mediates the anti-adipogenic action of lysophosphatidic acid through cross talking with the Rho/Rho associated kinase (ROCK) pathway.
Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20111201
Title: Synchronous phosphorylation of CPI-17 and MYPT1 is essential for inducing Ca(2+) sensitization in intestinal smooth muscle.
Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20111201
Title: Osteopontin is involved in urotensin II-induced migration of rat aortic adventitial fibroblasts.
Journal: Peptides 20111201
Title: LPA(1) -induced migration requires nonmuscle myosin II light chain phosphorylation in breast cancer cells.
Journal: Journal of cellular physiology 20111101
Title: Electrically guiding migration of human induced pluripotent stem cells.
Journal: Stem cell reviews 20111101
Title: Role of RhoA and its effectors ROCK and mDia1 in the modulation of deformation-induced FAK, ERK, p38, and MLC motogenic signals in human Caco-2 intestinal epithelial cells.
Journal: American journal of physiology. Cell physiology 20111101
Title: The Rho kinase inhibitor Y-27632 increases erythrocyte deformability and low oxygen tension-induced ATP release.
Journal: American journal of physiology. Heart and circulatory physiology 20111101
Title: Vascular smooth muscle cell migration induced by domains of thrombospondin-1 is differentially regulated.
Journal: American journal of surgery 20111101
Title: Amelioration of albuminuria in ROCK1 knockout mice with streptozotocin-induced diabetic kidney disease.
Journal: American journal of nephrology 20111101
Title: RhoA activation and effect of Rho-kinase inhibitor in the development of retinal neovascularization in a mouse model of oxygen-induced retinopathy.
Journal: Current eye research 20111101
Title: Dynamic ordering of nuclei in syncytial embryos: a quantitative analysis of the role of cytoskeletal networks.
Journal: Integrative biology : quantitative biosciences from nano to macro 20111101
Title: Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.
Journal: Nature biotechnology 20111101
Title: Rac-dependent doubling of HeLa cell area and impairment of cell migration and cell cycle by compounds from Iris germanica.
Journal: Protoplasma 20111001
Title: Protein prenylation contributes to the effects of LPS on EFS-induced responses in human isolated bronchi.
Journal: American journal of respiratory cell and molecular biology 20111001
Title: Capsaicinoids regulate airway anion transporters through Rho kinase- and cyclic AMP-dependent mechanisms.
Journal: American journal of respiratory cell and molecular biology 20111001
Title: Similar hydrodynamic and morphological changes in the aqueous humor outflow pathway after washout and Y27632 treatment in monkey eyes.
Journal: Experimental eye research 20111001
Title: Rho kinase-related proteins in human vaginal arteries: an immunohistochemical and functional study.
Journal: The journal of sexual medicine 20111001
Title: Rho-kinase inhibition ameliorates peritoneal fibrosis and angiogenesis in a rat model of peritoneal sclerosis.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110901
Title: In vitro differentiation of rat embryonic stem cells into functional cardiomyocytes.
Journal: Cell research 20110901
Title: Epithelial inducible nitric oxide synthase causes bacterial translocation by impairment of enterocytic tight junctions via intracellular signals of Rho-associated kinase and protein kinase C zeta.
Journal: Critical care medicine 20110901
Title: ROCK inhibition prevents fetal serum-induced alteration in structure and function of organ-cultured mesenteric artery.
Journal: Journal of muscle research and cell motility 20110901
Title: TGF-β2 reduces nitric oxide synthase mRNA through a ROCK-dependent pathway in airway epithelial cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20110901
Title: [Rho-kinase inhibitors].
Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20110901
Title: Rho kinase as a therapeutic target in cardiovascular disease.
Journal: Future cardiology 20110901
Title: Thrombin induces MCP-1 expression through Rho-kinase and subsequent p38MAPK/NF-κB signaling pathway activation in vascular endothelial cells.
Journal: Biochemical and biophysical research communications 20110812
Title: Aldosterone induction of hepatic stellate cell contraction through activation of RhoA/ROCK-2 signaling pathway.
Journal: Regulatory peptides 20110808
Title: A practical synthesis of Rho-Kinase inhibitor Y-27632 and fluoro derivatives and their evaluation in human pluripotent stem cells.
Journal: Organic & biomolecular chemistry 20110807
Title: Increased liver uptake and reduced hepatic stellate cell activation with a cell-specific conjugate of the Rho-kinase inhibitor Y27632.
Journal: Pharmaceutical research 20110801
Title: Immunocytochemical evidence for PDBu-induced activation of RhoA/ROCK in human internal anal sphincter smooth muscle cells.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20110801
Title: Protective effects of Y-27632 on hypoxia/reoxygenation-induced intestinal injury in newborn rats.
Journal: Journal of pediatric surgery 20110801
Title: [Activation of Rho-kinase pathway is involved in angiotensin II-induced contraction of human airway smooth muscle cells].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20110801
Title: Functional, morphological and molecular characterization of bladder dysfunction in streptozotocin-induced diabetic mice: evidence of a role for L-type voltage-operated Ca2+ channels.
Journal: British journal of pharmacology 20110701
Title: Regulation of V-ATPase recycling via a RhoA- and ROCKII-dependent pathway in epididymal clear cells.
Journal: American journal of physiology. Cell physiology 20110701
Title: Integrin α3 blockade enhances microtopographical down-regulation of α-smooth muscle actin: role of microtopography in ECM regulation.
Journal: Integrative biology : quantitative biosciences from nano to macro 20110701
Title: Effects of Rho-associated protein kinase inhibitors Y-27632 and Y-39983 on isolated rabbit ciliary arteries.
Journal: Japanese journal of ophthalmology 20110701
Title: Contribution of Rho-kinase to membrane excitability of murine colonic smooth muscle.
Journal: British journal of pharmacology 20110601
Title: Impaired Ca2+ handling in penile arteries from prediabetic Zucker rats: involvement of Rho kinase.
Journal: American journal of physiology. Heart and circulatory physiology 20110601
Title: Reduction of fibrogenesis by selective delivery of a Rho kinase inhibitor to hepatic stellate cells in mice.
Journal: The Journal of pharmacology and experimental therapeutics 20110601
Title: Increased contractility of hepatic stellate cells in cirrhosis is mediated by enhanced Ca2+-dependent and Ca2+-sensitization pathways.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20110601
Title: Rho kinase inhibitors stimulate the migration of human cultured osteoblastic cells by regulating actomyosin activity.
Journal: Cellular & molecular biology letters 20110601
Title: Sevoflurane inhibits angiotensin II-induced Rho kinase-mediated contraction of vascular smooth muscle from spontaneously hypertensive rat.
Journal: Journal of anesthesia 20110601
Title: Reactive oxygen species-dependent RhoA activation mediates collagen synthesis in hyperoxic lung fibrosis.
Journal: Free radical biology & medicine 20110601
Title: Chelerythrine perturbs lamellar actomyosin filaments by selective inhibition of myotonic dystrophy kinase-related Cdc42-binding kinase.
Journal: FEBS letters 20110506
Title: Differential role of Rho GTPases in intestinal epithelial barrier regulation in vitro.
Journal: Journal of cellular physiology 20110501
Title: Angiotensin II-induced vascular endothelial dysfunction through RhoA/Rho kinase/p38 mitogen-activated protein kinase/arginase pathway.
Journal: American journal of physiology. Cell physiology 20110501
Title: Rho signaling pathway and apical constriction in the early lens placode.
Journal: Genesis (New York, N.Y. : 2000) 20110501
Title: Regulation of MT1-MMP and MMP-2 by leptin in cardiac fibroblasts involves Rho/ROCK-dependent actin cytoskeletal reorganization and leads to enhanced cell migration.
Journal: Endocrinology 20110501
Title: [Production of connective tissue growth factor by angiotensin II in human embryonic lung fibroblast via RhoA-ROCK pathway].
Journal: Zhonghua yi xue za zhi 20110426
Title: Ca2+ sensitization and PKC contribute to exercise training-enhanced contractility in porcine collateral-dependent coronary arteries.
Journal: American journal of physiology. Heart and circulatory physiology 20110401
Title: Phospholipase Cdelta3 regulates RhoA/Rho kinase signaling and neurite outgrowth.
Journal: The Journal of biological chemistry 20110311
Title: LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress.
Journal: Cell stem cell 20110304
Title: Cryopreservation of human embryonic stem cells derived-cardiomyocytes induced by BMP2 in serum-free condition.
Journal: Reproductive sciences (Thousand Oaks, Calif.) 20110301
Title: ROCK and cAMP promote lymphatic endothelial cell barrier integrity and modulate histamine and thrombin-induced barrier dysfunction.
Journal: Lymphatic research and biology 20110301
Title: Advanced glycation end products induce moesin phosphorylation in murine brain endothelium.
Journal: Brain research 20110210
Title: Rho-kinase signalling regulates trypsinogen activation and tissue damage in severe acute pancreatitis.
Journal: British journal of pharmacology 20110201
Title: Effects of ischemic preconditioning on vascular reactivity and calcium sensitivity after hemorrhagic shock and their relationship to the RhoA–Rho-kinase pathway in rats.
Journal: Journal of cardiovascular pharmacology 20110201
Title: Characteristics of myogenic reactivity in isolated rat mesenteric veins.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20110201
Title: The Rho kinase pathway regulates mouse adult neural precursor cell migration.
Journal: Stem cells (Dayton, Ohio) 20110201
Title: Thromboxane A2 induces contraction of human prostate smooth muscle by Rho kinase- and calmodulin-dependent mechanisms.
Journal: European journal of pharmacology 20110115
Title: Rho-kinase inhibitor upregulates migration by altering focal adhesion formation via the Akt pathway in colon cancer cells.
Journal: European journal of pharmacology 20110110
Title: Rho-associated kinase plays a role in rabbit urethral smooth muscle contraction, but not via enhanced myosin light chain phosphorylation.
Journal: American journal of physiology. Renal physiology 20110101
Title: Inhibition of the Rho/ROCK pathway prevents neuronal degeneration in vitro and in vivo following methylmercury exposure.
Journal: Toxicology and applied pharmacology 20110101
Title: Chikungunya virus mobilizes the apoptotic machinery to invade host cell defenses.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110101
Title: RhoA/Rho kinase pathway contributes to the pathogenesis of thermal hyperalgesia in diabetic mice.
Journal: Pain 20110101
Title: Inhibition of Rho-kinase abrogates migration of human transitional cell carcinoma cells: results of an in vitro study.
Journal: Urologia internationalis 20110101
Title: The effect of lysophosphatidic acid and Rho-associated kinase patterning on adhesion of dental pulp cells.
Journal: International endodontic journal 20110101
Title: Fragment-based discovery of 6-substituted isoquinolin-1-amine based ROCK-I inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20110101
Title: ρ-Kinase inhibition reduces early microvascular leukocyte accumulation in the rat kidney following ischemia-reperfusion injury: roles of nitric oxide and blood flow.
Journal: Nephron. Experimental nephrology 20110101
Title: Geranylgeranyl-pyrophosphate regulates secretion of pentraxin 3 and monocyte chemoattractant protein-1 from rheumatoid fibroblast-like synoviocytes in distinct manners.
Journal: Clinical and experimental rheumatology 20110101
Title: ROCK inhibitor Y-27632 suppresses dissociation-induced apoptosis of murine prostate stem/progenitor cells and increases their cloning efficiency.
Journal: PloS one 20110101
Title: Actomyosin-dependent cortical dynamics contributes to the prophase force-balance in the early Drosophila embryo.
Journal: PloS one 20110101
Title: Na+/Ca2+ exchanger inhibitors inhibit neurite outgrowth in PC12 cells.
Journal: Journal of pharmacological sciences 20110101
Title: [The effect of Rho-kinase inhibition depends on the nature of factors that modify endothelial permeability].
Journal: Tsitologiia 20110101
Title: Inhibition of Rho-associated coiled-coil containing protein kinase enhances the activation of epidermal growth factor receptor in pancreatic cancer cells.
Journal: Molecular cancer 20110101
Title: Regulation of retinoschisin secretion in Weri-Rb1 cells by the F-actin and microtubule cytoskeleton.
Journal: PloS one 20110101
Title: Rho-Rho kinase pathway in the actomyosin contraction and cell-matrix adhesion in immortalized human trabecular meshwork cells.
Journal: Molecular vision 20110101
Title: Homocysteine induces phosphatidylserine exposure in cardiomyocytes through inhibition of Rho kinase and flippase activity.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101
Title: Co-crystal structures of inhibitors with MRCKβ, a key regulator of tumor cell invasion.
Journal: PloS one 20110101
Title: Decreases in CD31 and CD47 levels on the cell surface during etoposide-induced Jurkat cell apoptosis.
Journal: Biological & pharmaceutical bulletin 20110101
Title: Inhibition of Rho kinase regulates specification of early differentiation events in P19 embryonal carcinoma stem cells.
Journal: PloS one 20110101
Title: Lipid A decreases human erythrocytes deformability by increasing intracellular Ca(2+): effects of verapamil, staurosporine and the rho-kinase inhibitor Y-27632.
Journal: Clinical hemorheology and microcirculation 20110101
Title: Osteoclastogenic activity and RANKL expression are inhibited in osteoblastic cells expressing constitutively active Gα(12) or constitutively active RhoA.
Journal: Journal of cellular biochemistry 20101215
Title: Ouabain-induced apoptosis and Rho kinase: a novel caspase-2 cleavage site and fragment of Rock-2.
Journal: Apoptosis : an international journal on programmed cell death 20101201
Title: Oxidative stress and alterations in actin cytoskeleton trigger glutathione efflux in Saccharomyces cerevisiae.
Journal: Biochimica et biophysica acta 20101201
Title: Potentiation of nerve growth factor-induced neurite outgrowth by the ROCK inhibitor Y-27632: a possible role of IP₃ receptors.
Journal: European journal of pharmacology 20101201
Title: Rescue treatment with a Rho-kinase inhibitor normalizes right ventricular function and reverses remodeling in juvenile rats with chronic pulmonary hypertension.
Journal: American journal of physiology. Heart and circulatory physiology 20101201
Title: Identification and functional implication of a Rho kinase-dependent moesin-EBP50 interaction in noradrenaline-stimulated artery.
Journal: American journal of physiology. Cell physiology 20101201
Title: Effect of the Rho kinase inhibitor Y-27632 on the proteome of hearts with ischemia-reperfusion injury.
Journal: Proteomics 20101201
Title: Activation of PPAR-γ and PTEN cascade participates in lovastatin-mediated accelerated differentiation of oligodendrocyte progenitor cells.
Journal: Glia 20101101
Title: Modulation of the Rho/ROCK pathway in heart and lung after thorax irradiation reveals targets to improve normal tissue toxicity.
Journal: Current drug targets 20101101
Title: Inhibition of Rho-ROCK signaling induces apoptotic and non-apoptotic PS exposure in cardiomyocytes via inhibition of flippase.
Journal: Journal of molecular and cellular cardiology 20101101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Pharmacological inhibition of Rho-kinase (ROCK) signaling enhances cisplatin resistance in neuroblastoma cells.
Journal: International journal of oncology 20101101
Title: The origin recognition complex subunit, ORC3, is developmentally regulated and supports the expression of biochemical markers of neuronal maturation in cultured cerebellar granule cells.
Journal: Brain research 20101028
Title: Polarization and migration of hematopoietic stem and progenitor cells rely on the RhoA/ROCK I pathway and an active reorganization of the microtubule network.
Journal: The Journal of biological chemistry 20101008
Title: Acute and chronic alcohol exposure impair the phagocytosis of apoptotic cells and enhance the pulmonary inflammatory response.
Journal: Alcoholism, clinical and experimental research 20101001
Title: NF-κB as a common signaling pathway in ganglioside-induced autophagic cell death and activation of astrocytes.
Journal: Journal of neuroimmunology 20100914
Title: Balamuthia mandrillaris: role of galactose in encystment and identification of potential inhibitory targets.
Journal: Experimental parasitology 20100901
Title: Luteinizing hormone receptor-stimulated progesterone production by preovulatory granulosa cells requires protein kinase A-dependent activation/dephosphorylation of the actin dynamizing protein cofilin.
Journal: Molecular endocrinology (Baltimore, Md.) 20100901
Title: Dissecting the molecular architecture of integrin adhesion sites by cryo-electron tomography.
Journal: Nature cell biology 20100901
Title: Lovastatin inhibits EGFR dimerization and AKT activation in squamous cell carcinoma cells: potential regulation by targeting rho proteins.
Journal: Oncogene 20100819
Title: Lysophosphatidic acid signals through multiple receptors in osteoclasts to elevate cytosolic calcium concentration, evoke retraction, and promote cell survival.
Journal: The Journal of biological chemistry 20100813
Title: The mechanism by which RhoA regulates vascular reactivity after hemorrhagic shock in rats.
Journal: American journal of physiology. Heart and circulatory physiology 20100801
Title: Phosphatase of regenerating liver-1 promotes cell migration and invasion and regulates filamentous actin dynamics.
Journal: The Journal of pharmacology and experimental therapeutics 20100801
Title: Effect of low concentrations of hydrogen peroxide on the contractile responses of rat detrusor smooth muscle strips.
Journal: European journal of pharmacology 20100725
Title: Rho kinase activation and ROS production contributes to the cooling enhanced contraction in cutaneous equine digital veins.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20100701
Title: The protective effect of Rho-associated kinase inhibitor on aluminum-induced neurotoxicity in rat cortical neurons.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100701
Title: Analysis of responses to the Rho-kinase inhibitor Y-27632 in the pulmonary and systemic vascular bed of the rat.
Journal: American journal of physiology. Heart and circulatory physiology 20100701
Title: Acute hyperglycemia induces rapid, reversible increases in glomerular permeability in nondiabetic rats.
Journal: American journal of physiology. Renal physiology 20100601
Title: Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account.
Journal: Bioorganic & medicinal chemistry letters 20100601
Title: Enhancement of cell recovery for dissociated human embryonic stem cells after cryopreservation.
Journal: Biotechnology progress 20100501
Title: RhoA-Rho kinase signaling mediates endothelium- and endoperoxide-dependent contractile activities characteristic of hypertensive vascular dysfunction.
Journal: American journal of physiology. Heart and circulatory physiology 20100501
Title: Stimulatory effect of Rho-associated coiled-coil kinase (ROCK) inhibitor on revivability of in vitro-produced bovine blastocysts after vitrification.
Journal: Theriogenology 20100501
Title: [Effects of simvastatin on proliferation and transition of phenotype in PDGF-BB-induced pulmonary artery smooth muscle cells].
Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20100501
Title: Rho-kinase inhibitor attenuates cholestasis-induced CXC chemokine formation, leukocyte recruitment, and hepatocellular damage in the liver.
Journal: The Journal of surgical research 20100401
Title: Roles of lysophosphatidic acid and the Rho-associated kinase pathway in the migration of dental pulp cells.
Journal: Experimental cell research 20100401
Title: Up-regulation of the RhoA/Rho-kinase signaling pathway in corpus cavernosum from endothelial nitric-oxide synthase (NOS), but not neuronal NOS, null mice.
Journal: The Journal of pharmacology and experimental therapeutics 20100401
Title: Rho-kinase limits FGF-2-stimulated VEGF release in osteoblasts.
Journal: Bone 20100401
Title: Kupffer cell activation by hydrogen peroxide: a new mechanism of portal pressure increase.
Journal: Shock (Augusta, Ga.) 20100401
Title: Rho kinase inhibitor y27632 alters the balance between pluripotency and early differentiation events in human embryonic stem cells.
Journal: Current stem cell research & therapy 20100301
Title: Presence of a ROCK inhibitor in extracellular matrix supports more undifferentiated growth of feeder-free human embryonic and induced pluripotent stem cells upon passaging.
Journal: Stem cell reviews 20100301
Title: Rho kinase inhibitor Y-27632 facilitates recovery from experimental peripheral neuropathy induced by anti-cancer drug cisplatin.
Journal: Neurotoxicology 20100301
Title: Integrins stimulate E-cadherin-mediated intercellular adhesion by regulating Src-kinase activation and actomyosin contractility.
Journal: Journal of cell science 20100301
Title: ROCK inhibition facilitates tissue reconstitution from embryonic kidney cell suspensions.
Journal: Kidney international 20100301
Title: Protective effects of Y-27632 on acute dichlorvos poisoning in rats.
Journal: The American journal of emergency medicine 20100301
Title: Rho kinase inhibition protects CA1 cells in organotypic hippocampal slices during in vitro ischemia.
Journal: Brain research 20100226
Title: N-acetylcysteine inhibits RhoA and promotes apoptotic cell clearance during intense lung inflammation.
Journal: American journal of respiratory and critical care medicine 20100215
Title: Effects of rho-kinase inhibition on pulmonary hypertension, lung growth, and structure in neonatal rats chronically exposed to hypoxia.
Journal: Pediatric research 20100201
Title: Endothelial P2Y2 receptor regulates LPS-induced neutrophil transendothelial migration in vitro.
Journal: Molecular immunology 20100201
Title: Dynamic regulation of ROCK in tumor cells controls CXCR4-driven adhesion events.
Journal: Journal of cell science 20100201
Title: Features of distinct contractions induced with a high and a low concentration of KCl, noradrenaline, and histamine in swine lingual artery.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20100201
Title: Hit to lead account of the discovery of bisbenzamide and related ureidobenzamide inhibitors of Rho kinase.
Journal: Journal of medicinal chemistry 20100128
Title: Promigratory and procontractile growth factor environments differentially regulate cell morphogenesis.
Journal: Experimental cell research 20100115
Title: The suppressive effect of Rho kinase inhibitor, Y-27632, on oncogenic Ras/RhoA induced invasion/migration of human bladder cancer TSGH cells.
Journal: Chemico-biological interactions 20100105
Title: Interactive role of protein phosphatase 2A and protein kinase Calpha in the stretch-induced triphosphorylation of myosin light chain in canine cerebral artery.
Journal: Journal of vascular research 20100101
Title: Alginate microcapsule for propagation and directed differentiation of hESCs to definitive endoderm.
Journal: Biomaterials 20100101
Title: New approaches to the treatment of pulmonary hypertension: from bench to bedside.
Journal: Cardiology in review 20100101
Title: Rho kinases regulate the renewal and neural differentiation of embryonic stem cells in a cell plating density-dependent manner.
Journal: PloS one 20100101
Title: Type I interferon (IFN-alpha/beta) rescues B-lymphocytes from apoptosis via PI3Kdelta/Akt, Rho-A, NFkappaB and Bcl-2/Bcl(XL).
Journal: Cellular immunology 20100101
Title: Adult rats are more sensitive to the vascular effects induced by hyperhomocysteinemia than young rats.
Journal: Vascular pharmacology 20100101
Title: Modification of the detrimental effect of TNF-α on human endothelial progenitor cells by fasudil and Y27632.
Journal: Journal of biochemical and molecular toxicology 20100101
Title: The ROCK inhibitor Y-27632 improves recovery of human embryonic stem cells after fluorescence-activated cell sorting with multiple cell surface markers.
Journal: PloS one 20100101
Title: Combined inhibition of Cdk5 and ROCK additively increase cell survival, but not the regenerative response in regenerating retinal ganglion cells.
Journal: Molecular and cellular neurosciences 20091201
Title: Nitric oxide inhibits endothelin-1-induced neonatal cardiomyocyte hypertrophy via a RhoA-ROCK-dependent pathway.
Journal: Journal of molecular and cellular cardiology 20091201
Title: Involvement of Rho-kinase in tumor necrosis factor-alpha-induced interleukin-6 release from C6 glioma cells.
Journal: Neurochemistry international 20091101
Title: Involvement of Rho-kinase in prostaglandin E(1)-stimulated VEGF synthesis through stress-activated protein kinase/c-Jun N-terminal kinase in osteoblast-like MC3T3-E1 cells.
Journal: Prostaglandins & other lipid mediators 20091101
Title: Inhibition of geranylgeranyltransferase inhibits bronchial smooth muscle hyperresponsiveness in mice.
Journal: American journal of physiology. Lung cellular and molecular physiology 20091101
Title: Triazine and pyrimidine based ROCK inhibitors with efficacy in spontaneous hypertensive rat model.
Journal: Bioorganic & medicinal chemistry letters 20091101
Title: ROCK mediates phorbol ester-induced apoptosis in prostate cancer cells via p21Cip1 up-regulation and JNK.
Journal: The Journal of biological chemistry 20091023
Title: Substrate specificity and inhibitors of LRRK2, a protein kinase mutated in Parkinson's disease.
Journal: The Biochemical journal 20091023
Title: Comparative screening of glial cell types reveals extracellular matrix that inhibits retinal axon growth in a chondroitinase ABC-resistant fashion.
Journal: Glia 20091001
Title: Suppression of hepatitis C virus replication by protein kinase C-related kinase 2 inhibitors that block phosphorylation of viral RNA polymerase.
Journal: Journal of viral hepatitis 20091001
Title: ROCK inhibition promotes adult retinal ganglion cell neurite outgrowth only in the presence of growth promoting factors.
Journal: Molecular and cellular neurosciences 20091001
Title: Agonist-biased signaling via proteinase activated receptor-2: differential activation of calcium and mitogen-activated protein kinase pathways.
Journal: Molecular pharmacology 20091001
Title: Calcium-dependent and calcium-independent inhibition of contraction by cGMP/cGKI in intestinal smooth muscle.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20091001
Title: Statin's excitoprotection is mediated by sAPP and the subsequent attenuation of calpain-induced truncation events, likely via rho-ROCK signaling.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090909
Title: Pharmacological characterization of SAR407899, a novel rho-kinase inhibitor.
Journal: Hypertension (Dallas, Tex. : 1979) 20090901
Title: In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction.
Journal: Journal of cell science 20090901
Title: Analogues of Y27632 increase gap junction communication and suppress the formation of transformed NIH3T3 colonies.
Journal: British journal of cancer 20090901
Title: Rho-mediated regulation of TGF-beta1- and FGF-2-induced activation of corneal stromal keratocytes.
Journal: Investigative ophthalmology & visual science 20090801
Title: Cyclic mechanical stress and trabecular meshwork cell contractility.
Journal: Investigative ophthalmology & visual science 20090801
Title: Enhancement on primate corneal endothelial cell survival in vitro by a ROCK inhibitor.
Journal: Investigative ophthalmology & visual science 20090801
Title: Carbohydrate analysis of Acanthamoeba castellanii.
Journal: Experimental parasitology 20090801
Title: Impaired cAMP and Rac 1 signaling contribute to TNF-alpha-induced endothelial barrier breakdown in microvascular endothelium.
Journal: Microcirculation (New York, N.Y. : 1994) 20090801
Title: Rho-kinase inhibitors Y-27632 and fasudil prevent agonist-induced vasospasm in human radial artery.
Journal: Canadian journal of physiology and pharmacology 20090801
Title: Rho GTPase signaling and PTH 3-34, but not PTH 1-34, maintain the actin cytoskeleton and antagonize bisphosphonate effects in mouse osteoblastic MC3T3-E1 cells.
Journal: Bone 20090701
Title: Localization of diacylglycerol kinase epsilon on stress fibers in vascular smooth muscle cells.
Journal: Cell and tissue research 20090701
Title: Involvement of Rho-kinase in sphingosine 1-phosphate-stimulated HSP27 induction in osteoblasts.
Journal: International journal of molecular medicine 20090701
Title: Lysophosphatidylcholine induces glial cell activation: role of rho kinase.
Journal: Glia 20090601
Title: The Rho-kinase inhibitor Y-27632 inhibits cholestasis-induced platelet interactions in the hepatic microcirculation.
Journal: Microvascular research 20090601
Title: Decreased intraocular pressure in mice following either pharmacological or genetic inhibition of ROCK.
Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20090601
Title: Rho kinase inhibitor Y-27632 down-regulates norepinephrine synthesis and release in PC12 cells.
Journal: Basic & clinical pharmacology & toxicology 20090601
Title: Time-dependent phenotypic and contractile changes of pulmonary artery in chronic hypoxia-induced pulmonary hypertension.
Journal: Journal of pharmacological sciences 20090601
Title: Role of the Rho-ROCK (Rho-associated kinase) signaling pathway in the regulation of pancreatic beta-cell function.
Journal: Endocrinology 20090501
Title: Rho kinase inhibitors prevent endothelium-dependent contractions in the rat aorta.
Journal: The Journal of pharmacology and experimental therapeutics 20090501
Title: Rho kinase inhibition attenuates LPS-induced renal failure in mice in part by attenuation of NF-kappaB p65 signaling.
Journal: American journal of physiology. Renal physiology 20090501
Title: A rapid, PPAR-gamma-dependent effect of pioglitazone on the phosphorylation of MYPT.
Journal: American journal of physiology. Cell physiology 20090501
Title: The Rho-A/Rho-kinase pathway is up-regulated but remains inhibited by cyclic guanosine monophosphate-dependent mechanisms during endotoxemia in small mesenteric arteries.
Journal: Critical care medicine 20090501
Title: Vascular dysfunction in septic shock--any ROCKing news?
Journal: Critical care medicine 20090501
Title: ROCKs are expressed in brain tumors and are required for glioma-cell migration on myelinated axons.
Journal: Glia 20090401
Title: Roles of focal adhesions and fibronectin-mediated cohesion in proliferation of confluent fibroblasts.
Journal: Journal of cellular physiology 20090401
Title: Rho GTPases in hepatocellular carcinoma.
Journal: Biochimica et biophysica acta 20090401
Title: Rho-kinase-mediated suppression of KDR current in cerebral arteries requires an intact actin cytoskeleton.
Journal: American journal of physiology. Heart and circulatory physiology 20090401
Title: Participation of Rho-associated kinase in electrical stimulated and acetylcholine-induced contraction of feline esophageal smooth muscle.
Journal: European journal of pharmacology 20090401
Title: Y27632, a Rho-activated kinase inhibitor, normalizes dysregulation in alpha1-adrenergic receptor-induced contraction of Lyon hypertensive rat artery smooth muscle.
Journal: Fundamental & clinical pharmacology 20090401
Title: Myosin light chain phosphatase activation is involved in the hydrogen sulfide-induced relaxation in mouse gastric fundus.
Journal: European journal of pharmacology 20090315
Title: The role of lysophosphatidic acid receptor (LPA1) in the oxygen-induced retinal ganglion cell degeneration.
Journal: Investigative ophthalmology & visual science 20090301
Title: ROCK inhibitor improves survival of cryopreserved serum/feeder-free single human embryonic stem cells.
Journal: Human reproduction (Oxford, England) 20090301
Title: Superoxide constricts rat pulmonary arteries via Rho-kinase-mediated Ca(2+) sensitization.
Journal: Free radical biology & medicine 20090301
Title: Erectile function in two-kidney, one-clip hypertensive rats is maintained by a potential increase in nitric oxide production.
Journal: The journal of sexual medicine 20090301
Title: Cardioprotective effects of pitavastatin on cardiac performance and remodeling in failing rat hearts.
Journal: American journal of hypertension 20090201
Title: Role of protease-activated receptor-1 in endothelial nitric oxide synthase-Thr495 phosphorylation.
Journal: Experimental biology and medicine (Maywood, N.J.) 20090201
Title: Role of Ca2+ mobilization and Ca2+ sensitization in 8-iso-PGF 2 alpha-induced contraction in airway smooth muscle.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20090201
Title: EphA1 interacts with integrin-linked kinase and regulates cell morphology and motility.
Journal: Journal of cell science 20090115
Title: Lipocalin-2 is an autocrine mediator of reactive astrocytosis.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090107
Title: ROCK-regulated cytoskeletal dynamics participate in the inhibitory effect of melatonin on cancer cell migration.
Journal: Journal of pineal research 20090101
Title: Adreno-muscarinic synergy in the bladder trigone: calcium-dependent and -independent mechanisms.
Journal: Cell calcium 20090101
Title: The small GTPase Rho mediates articular chondrocyte phenotype and morphology in response to interleukin-1alpha and insulin-like growth factor-I.
Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20090101
Title: Serofendic acid promotes stellation induced by cAMP and cGMP analogs in cultured cortical astrocytes.
Journal: Journal of pharmacological sciences 20090101
Title: Possible mechanisms underlying statin-induced skeletal muscle toxicity in L6 fibroblasts and in rats.
Journal: Journal of pharmacological sciences 20090101
Title: Modulation of human uterine smooth muscle cell collagen contractility by thrombin, Y-27632, TNF alpha and indomethacin.
Journal: Reproductive biology and endocrinology : RB&E 20090101
Title: Expression of RhoA mRNA and activated RhoA in urothelium and smooth muscle, and effects of a Rho-kinase inhibitor on contraction of the porcine urinary bladder.
Journal: Neurourology and urodynamics 20090101
Title: Obstruction alters muscarinic receptor-coupled RhoA/Rho-kinase pathway in the urinary bladder of the rat.
Journal: Neurourology and urodynamics 20090101
Title: In vivo imaging and quantitative analysis of leukocyte directional migration and polarization in inflamed tissue.
Journal: PloS one 20090101
Title: Signaling through Rho GTPase pathway as viable drug target.
Journal: Current medicinal chemistry 20090101
Title: Contractility of diabetic human corpus cavernosum smooth muscle in response to serotonin mediated via Rho-kinase.
Journal: Pharmacology 20090101
Title: Role of Rho/Rho-kinase and NO/cGMP signaling pathways in vascular function prior to atherosclerosis.
Journal: Journal of atherosclerosis and thrombosis 20090101
Title: Y-27632 enhances differentiation of blastocyst like cystic human embryoid bodies to endocrinologically active trophoblast cells on a biomimetic platform.
Journal: Journal of biomedical science 20090101
Title: Rearrangements of the actin cytoskeleton and E-cadherin-based adherens junctions caused by neoplasic transformation change cell-cell interactions.
Journal: PloS one 20090101
Title: Concomitant inhibition of prolyl hydroxylases and ROCK initiates differentiation of mesenchymal stem cells and PC12 towards the neuronal lineage.
Journal: Biochemical and biophysical research communications 20081212
Title: Aldosterone induces myofibroblastic transdifferentiation and collagen gene expression through the Rho-kinase dependent signaling pathway in rat mesangial cells.
Journal: Experimental cell research 20081210
Title: The anandamide analog, Met-F-AEA, controls human breast cancer cell migration via the RHOA/RHO kinase signaling pathway.
Journal: Endocrine-related cancer 20081201
Title: Role of src-family kinases in hypoxic vasoconstriction of rat pulmonary artery.
Journal: Cardiovascular research 20081201
Title: Notch3 is a major regulator of vascular tone in cerebral and tail resistance arteries.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20081201
Title: The ROCK inhibitor Y-27632 enhances the survival rate of human embryonic stem cells following cryopreservation.
Journal: Stem cells and development 20081201
Title: Y-27632 augments the isoflurane-induced relaxation of bronchial smooth muscle in rats.
Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20081201
Title: Apolipoprotein(a), through its strong lysine-binding site in KIV(10'), mediates increased endothelial cell contraction and permeability via a Rho/Rho kinase/MYPT1-dependent pathway.
Journal: The Journal of biological chemistry 20081107
Title: Activation of Rho-kinase in the brainstem enhances sympathetic drive in mice with heart failure.
Journal: Autonomic neuroscience : basic & clinical 20081103
Title: Dual pathway activated by tert-butyl hydroperoxide in human airway anion secretion.
Journal: The Journal of pharmacology and experimental therapeutics 20081101
Title: Rho-associated kinase inhibitor Y-27632 promotes survival of cynomolgus monkey embryonic stem cells.
Journal: Molecular human reproduction 20081101
Title: Antiinflammatory effect of Rho kinase blockade via inhibition of NF-kappaB activation in rheumatoid arthritis.
Journal: Arthritis and rheumatism 20081101
Title: Identification of the Rock-dependent transcriptome in rodent fibroblasts.
Journal: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20081101
Title: Rho/ROCK/actin signaling regulates membrane androgen receptor induced apoptosis in prostate cancer cells.
Journal: Experimental cell research 20081015
Title: Demonstration of elevation and localization of Rho-kinase activity in the brain of a rat model of cerebral infarction.
Journal: European journal of pharmacology 20081010
Title: Calcium sensitization in human esophageal muscle: role for RhoA kinase in maintenance of lower esophageal sphincter tone.
Journal: The Journal of pharmacology and experimental therapeutics 20081001
Title: Effects of a selective Rho-kinase inhibitor Y-27632 on oxidative stress parameters in acute dichlorvos poisoning in rats.
Journal: Cell biochemistry and function 20081001
Title: Novel interactions between the 5-HT transporter, 5-HT1B receptors and Rho kinase in vivo and in pulmonary fibroblasts.
Journal: British journal of pharmacology 20081001
Title: RhoA silencing reverts the resistance to doxorubicin in human colon cancer cells.
Journal: Molecular cancer research : MCR 20081001
Title: [Human pluripotent stem cell and neural differentiation].
Journal: Brain and nerve = Shinkei kenkyu no shinpo 20081001
Title: Detection of myosin light chain phosphorylation--a cell-based assay for screening Rho-kinase inhibitors.
Journal: Biochemical and biophysical research communications 20080919
Title: Role of RhoA in activity-dependent cortical axon branching.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080910
Title: Antiepileptic effects of two Rho-kinase inhibitors, Y-27632 and fasudil, in mice.
Journal: British journal of pharmacology 20080901
Title: Regulation of polarity in cells devoid of actin bundle system after treatment with inhibitors of myosin II activity.
Journal: Cell motility and the cytoskeleton 20080901
Title: Statins inhibit toll-like receptor 4-mediated lipopolysaccharide signaling and cytokine expression.
Journal: Pharmacogenetics and genomics 20080901
Title: H89 (N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide) induces reduction of myosin regulatory light chain phosphorylation and inhibits cell proliferation.
Journal: European journal of pharmacology 20080820
Title: Effects of endothelin-1 on calcium-independent contraction of bovine trabecular meshwork.
Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20080801
Title: Rotenone-induced toxicity is mediated by Rho-GTPases in hippocampal neurons.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080801
Title: Rho kinases regulate corneal epithelial wound healing.
Journal: American journal of physiology. Cell physiology 20080801
Title: Myosin light chain kinase activation and calcium sensitization in smooth muscle in vivo.
Journal: American journal of physiology. Cell physiology 20080801
Title: High glucose-induced upregulation of Rho/Rho-kinase via platelet-derived growth factor receptor-beta increases migration of aortic smooth muscle cells.
Journal: Journal of molecular and cellular cardiology 20080801
Title: Rho-kinase signalling mediates endotoxin hypersensitivity after partial hepatectomy.
Journal: The British journal of surgery 20080801
Title: Rho-associated kinases are crucial for myofibroblast differentiation and production of extracellular matrix in scleroderma fibroblasts.
Journal: Arthritis and rheumatism 20080801
Title: Simvastatin inhibits central sympathetic outflow in heart failure by a nitric-oxide synthase mechanism.
Journal: The Journal of pharmacology and experimental therapeutics 20080701
Title: The inhaled Rho kinase inhibitor Y-27632 protects against allergen-induced acute bronchoconstriction, airway hyperresponsiveness, and inflammation.
Journal: American journal of physiology. Lung cellular and molecular physiology 20080701
Title: Anti-cancer drug induced neurotoxicity and identification of Rho pathway signaling modulators as potential neuroprotectants.
Journal: Neurotoxicology 20080701
Title: Adenosine-oligoarginine conjugate, a novel bisubstrate inhibitor, effectively dissociates the actin cytoskeleton.
Journal: The FEBS journal 20080701
Title: Possible involvement of Rho-kinase in aldosterone-induced vascular smooth muscle cell remodeling.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20080701
Title: Rho-kinase inhibitors augment the inhibitory effect of propofol on rat bronchial smooth muscle contraction.
Journal: Anesthesia and analgesia 20080601
Title: Fasudil-induced hypoxia-inducible factor-1alpha degradation disrupts a hypoxia-driven vascular endothelial growth factor autocrine mechanism in endothelial cells.
Journal: Molecular cancer therapeutics 20080601
Title: [Optic nerve regeneration in adult mammals].
Journal: Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20080601
Title: Melatonin restores impaired contractility in aged guinea pig urinary bladder.
Journal: Journal of pineal research 20080501
Title: Contractile changes of the clitoral cavernous smooth muscle in female rabbits with experimentally induced overactive bladder.
Journal: The journal of sexual medicine 20080501
Title: Prolactin stimulates transepithelial calcium transport and modulates paracellular permselectivity in Caco-2 monolayer: mediation by PKC and ROCK pathways.
Journal: American journal of physiology. Cell physiology 20080501
Title: Inorganic arsenic activates reduced NADPH oxidase in human primary macrophages through a Rho kinase/p38 kinase pathway.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20080501
Title: Effects of atorvastatin and pravastatin on signal transduction related to glucose uptake in 3T3L1 adipocytes.
Journal: Journal of pharmacological sciences 20080501
Title: High glucose increases phosphocofilin via phosphorylation of LIM kinase due to Rho/Rho kinase activation in cultured pig proximal tubular epithelial cells.
Journal: Diabetes research and clinical practice 20080401
Title: Low intensity pulsed ultrasound accelerates macrophage phagocytosis by a pathway that requires actin polymerization, Rho, and Src/MAPKs activity.
Journal: Cellular signalling 20080401
Title: Rho kinase is involved in Ca2+ entry of rat penile small arteries.
Journal: American journal of physiology. Heart and circulatory physiology 20080401
Title: Beneficial effects of the Rho kinase inhibitor Y27632 in murine puromycin aminonucleoside nephrosis.
Journal: Kidney & blood pressure research 20080401
Title: Characterizations of sphingosylphosphorylcholine-induced scratching responses in ICR mice using naltrexon, capsaicin, ketotifen and Y-27632.
Journal: European journal of pharmacology 20080331
Title: Differential effects of two ROCK inhibitors, Fasudil and Y-27632, on optic nerve regeneration in adult cats.
Journal: Brain research 20080327
Title: Proinsulin C-peptide constricts glomerular afferent arterioles in diabetic mice. A potential renoprotective mechanism.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20080301
Title: Roles of Rho guanosine 5'-triphosphatase A, Rho kinases, and extracellular signal regulated kinase (1/2) in prostaglandin E2-mediated migration of first-trimester human extravillous trophoblast.
Journal: Endocrinology 20080301
Title: Rho-kinase-dependent F-actin rearrangement is involved in the inhibition of PI3-kinase/Akt during ischemia-reperfusion-induced endothelial cell apoptosis.
Journal: Apoptosis : an international journal on programmed cell death 20080301
Title: Selectivity of ROCK inhibitors in the spontaneously tonic smooth muscle.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20080301
Title: Rho kinase inhibition: a new approach for treating diabetic nephropathy?
Journal: Diabetes 20080301
Title: Purkinje cell survival in organotypic cultures: implication of Rho and its downstream effector ROCK.
Journal: Journal of neuroscience research 20080215
Title: Aggrecan components differentially modulate nerve growth factor-responsive and neurotrophin-3-responsive dorsal root ganglion neurite growth.
Journal: Journal of neuroscience research 20080215
Title: In vivo phosphorylation of regulatory light chain of myosin II in sea urchin eggs and its role in controlling myosin localization and function during cytokinesis.
Journal: Cell motility and the cytoskeleton 20080201
Title: Acute vasodilator effects of Rho-kinase inhibitors in neonatal rats with pulmonary hypertension unresponsive to nitric oxide.
Journal: American journal of physiology. Lung cellular and molecular physiology 20080201
Title: The small GTPase Rac-1 is a regulator of mesangial cell morphology and thrombospondin-1 expression.
Journal: American journal of physiology. Renal physiology 20080201
Title: The mechanism of increasing outflow facility by rho-kinase inhibition with Y-27632 in bovine eyes.
Journal: Experimental eye research 20080201
Title: Nitric oxide does not downregulate Rho-kinase (ROCK-2) expression in rat coronary endothelial cells.
Journal: Journal of cardiovascular pharmacology 20080201
Title: Y-27632, a Rho-associated protein kinase inhibitor, attenuates neuronal cell death after transient retinal ischemia.
Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20080101
Title: Changes in the smooth muscle of the corpora cavernosum related to reversal of partial bladder outlet obstruction in rabbits.
Journal: Journal of andrology 20080101
Title: Heterogeneity in 5-HT-induced contractile and proliferative responses in rat pulmonary arterial bed.
Journal: Journal of vascular research 20080101
Title: ROCK inhibition and CNTF interact on intrinsic signalling pathways and differentially regulate survival and regeneration in retinal ganglion cells.
Journal: Brain : a journal of neurology 20080101
Title: Thromboxane A2 receptors in prostate carcinoma: expression and its role in regulating cell motility via small GTPase Rho.
Journal: Cancer research 20080101
Title: Analysis of the pattern of subcellular force generation by corneal fibroblasts after Rho activation.
Journal: Eye & contact lens 20080101
Title: Analysis of Rho-GTPase mimicry by a family of bacterial type III effector proteins.
Journal: Methods in enzymology 20080101
Title: Function of Rho-kinase in prostaglandin D2-induced interleukin-6 synthesis in osteoblasts.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20080101
Title: Simvastatin suppresses the differentiation of C2C12 myoblast cells via a Rac pathway.
Journal: Journal of muscle research and cell motility 20080101
Title: A negative modulatory role for rho and rho-associated kinase signaling in delamination of neural crest cells.
Journal: Neural development 20080101
Title: Abelson tyrosine kinase links PDGFbeta receptor activation to cytoskeletal regulation of NMDA receptors in CA1 hippocampal neurons.
Journal: Molecular brain 20080101
Title: [The contribution of protein kinase C and Rho-kinase to the control of the receptor-dependent artery contraction decreases with age independently of sympathetic innervation].
Journal: Biofizika 20080101
Title: A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20071218
Title: The selectivity of protein kinase inhibitors: a further update.
Journal: The Biochemical journal 20071215
Title: Endothelin-1 and serotonin are involved in activation of RhoA/Rho kinase signaling in the chronically hypoxic hypertensive rat pulmonary circulation.
Journal: Journal of cardiovascular pharmacology 20071201
Title: Contraction of tubulointerstitial fibrosis tissue in diabetic nephropathy, as demonstrated in an in vitro fibrosis model.
Journal: Virchows Archiv : an international journal of pathology 20071101
Title: Rho/Rho kinase is a key enzyme system involved in the angiotensin II signaling pathway of liver fibrosis and steatosis.
Journal: Journal of gastroenterology and hepatology 20071101
Title: Attenuation of actinomyosinII contractile activity in growth cones accelerates filopodia-guided and microtubule-based neurite elongation.
Journal: Brain research 20071024
Title: Volatile anesthetics affect the morphology of rat glioma C6 cells via RhoA, ERK, and Akt activation.
Journal: Journal of cellular biochemistry 20071001
Title: Intracellular signalling pathways in the vasoconstrictor response of mouse afferent arterioles to adenosine.
Journal: Acta physiologica (Oxford, England) 20071001
Title: Inhibition of Rho kinase (ROCK) increases neurite outgrowth on chondroitin sulphate proteoglycan in vitro and axonal regeneration in the adult optic nerve in vivo.
Journal: Journal of neurochemistry 20071001
Title: Rho guanosine 5'-triphosphatases differentially regulate insulin-like growth factor I (IGF-I) receptor-dependent and -independent actions of IGF-II on human trophoblast migration.
Journal: Endocrinology 20071001
Title: Characterization of protein kinase pathways responsible for Ca2+ sensitization in rat ileal longitudinal smooth muscle.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20071001
Title: Sphingosine 1-phosphate rapidly increases endothelial barrier function independently of VE-cadherin but requires cell spreading and Rho kinase.
Journal: American journal of physiology. Cell physiology 20071001
Title: RhoA required for acid-induced stress fiber formation and trafficking and activation of NHE3.
Journal: American journal of physiology. Renal physiology 20071001
Title: Optimizing nitric oxide production by time dependent L-arginine administration in isolated human corpus cavernosum.
Journal: The Journal of urology 20071001
Title: Microtubule regulation of corneal fibroblast morphology and mechanical activity in 3-D culture.
Journal: Experimental eye research 20071001
Title: [Advances in the study of Rho kinase and its inhibitors].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20071001
Title: Role of alpha2C-adrenoceptors in the reduction of skin blood flow induced by local cooling in mice.
Journal: British journal of pharmacology 20070901
Title: VIP induces the elongation of dendrites and axons in cultured hippocampal neurons: role of microtubules.
Journal: Peptides 20070901
Title: Simvastatin enhances induction of inducible nitric oxide synthase in 3T3-L1 adipocytes.
Journal: Free radical research 20070901
Title: Comparative pharmacological analysis of Rho-kinase inhibitors and identification of molecular components of Ca2+ sensitization in the rat lower urinary tract.
Journal: Biochemical pharmacology 20070815
Title: Vasoconstrictor effect of endothelin-1 on hypertensive pulmonary arterial smooth muscle involves Rho-kinase and protein kinase C.
Journal: American journal of physiology. Lung cellular and molecular physiology 20070801
Title: Dynamics of actin filaments during tension-dependent formation of actin bundles.
Journal: Biochimica et biophysica acta 20070801
Title: Rho inhibition induces migration of mesenchymal stromal cells.
Journal: Stem cells (Dayton, Ohio) 20070801
Title: The rho-kinase inhibitors Y-27632 and fasudil act synergistically with imatinib to inhibit the expansion of ex vivo CD34(+) CML progenitor cells.
Journal: Leukemia 20070801
Title: Pericyte Rho GTPase mediates both pericyte contractile phenotype and capillary endothelial growth state.
Journal: The American journal of pathology 20070801
Title: Simvastatin inhibits TNFalpha-induced invasion of human cardiac myofibroblasts via both MMP-9-dependent and -independent mechanisms.
Journal: Journal of molecular and cellular cardiology 20070801
Title: Increased PDZ-RhoGEF/RhoA/Rho kinase signaling in small mesenteric arteries of angiotensin II-induced hypertensive rats.
Journal: Journal of hypertension 20070801
Title: Small-molecule therapies for cardiac hypertrophy: moving beneath the cell surface.
Journal: Nature reviews. Drug discovery 20070801
Title: Effects of Rho-kinase and Src protein tyrosine kinase inhibition on agonist-induced vasoconstriction of arteries and veins of the equine laminar dermis.
Journal: American journal of veterinary research 20070801
Title: A minor role for Ca2+ sensitization in sustained contraction through activation of muscarinic receptor in circular muscle of rat distal colon.
Journal: Pflugers Archiv : European journal of physiology 20070701
Title: Acute inhibition of Rho-kinase improves cardiac contractile function in streptozotocin-diabetic rats.
Journal: Cardiovascular research 20070701
Title: Insulin increases the expression of contractile phenotypic markers in airway smooth muscle.
Journal: American journal of physiology. Cell physiology 20070701
Title: Crosstalk between HIF-1 and ROCK pathways in neuronal differentiation of mesenchymal stem cells, neurospheres and in PC12 neurite outgrowth.
Journal: Molecular and cellular neurosciences 20070701
Title: Differential effects of phenylalanine on Rac1, Cdc42, and RhoA expression and activity in cultured cortical neurons.
Journal: Pediatric research 20070701
Title: Role of the small GTPase RhoA in the hypoxia-induced decrease of plasma membrane Na,K-ATPase in A549 cells.
Journal: Journal of cell science 20070701
Title: Vasorelaxing effect of the Rho-kinase inhibitor, Y-27632, in isolated canine basilar arteries.
Journal: Neurological research 20070701
Title: Pravastatin induces thrombomodulin expression in TNFalpha-treated human aortic endothelial cells by inhibiting Rac1 and Cdc42 translocation and activity.
Journal: Journal of cellular biochemistry 20070601
Title: Rho kinase activation plays a major role as a mediator of irreversible injury in reperfused myocardium.
Journal: American journal of physiology. Heart and circulatory physiology 20070601
Title: The RISK of ROCK.
Journal: American journal of physiology. Heart and circulatory physiology 20070601
Title: Asbestos induces nitric oxide synthesis in mesothelioma cells via Rho signaling inhibition.
Journal: American journal of respiratory cell and molecular biology 20070601
Title: Sphingosine-1-phosphate receptor expression in cardiac fibroblasts is modulated by in vitro culture conditions.
Journal: American journal of physiology. Heart and circulatory physiology 20070601
Title: Protein kinase A inhibits lysophosphatidic acid-induced migration of airway smooth muscle cells.
Journal: The Journal of pharmacology and experimental therapeutics 20070601
Title: Cellular regulation of basal tone in internal anal sphincter smooth muscle by RhoA/ROCK.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20070601
Title: Extracellular ATP induces assembly and activation of the myosin light chain phosphatase complex in endothelial cells.
Journal: Cardiovascular research 20070601
Title: Roles of P2X receptors and Ca2+ sensitization in extracellular adenosine triphosphate-induced hyperresponsiveness in airway smooth muscle.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20070601
Title: Somatostatin induces rapid contraction of neuroendocrine cells.
Journal: FEBS letters 20070515
Title: Heat shock augments myosin phosphatase target-subunit phosphorylation.
Journal: Biochemical and biophysical research communications 20070511
Title: Hypertonicity triggers RhoA-dependent assembly of myosin-containing striated polygonal actin networks in endothelial cells.
Journal: American journal of physiology. Cell physiology 20070501
Title: Increased arginase activity and endothelial dysfunction in human inflammatory bowel disease.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20070501
Title: Rho-family small GTPases are involved in forskolin-induced cell-cell contact formation of renal glomerular podocytes in vitro.
Journal: Cell and tissue research 20070501
Title: Cytoskeleton/stretch-activated ion channel interaction regulates myogenic differentiation of skeletal myoblasts.
Journal: Journal of cellular physiology 20070501
Title: A novel ROCK inhibitor, Y-39983, promotes regeneration of crushed axons of retinal ganglion cells into the optic nerve of adult cats.
Journal: Experimental neurology 20070501
Title: The P2Y2 nucleotide receptor requires interaction with alpha v integrins to access and activate G12.
Journal: Journal of cell science 20070501
Title: Influence of actin cytoskeletal integrity on matrix metalloproteinase-2 activation in cultured human trabecular meshwork cells.
Journal: Investigative ophthalmology & visual science 20070501
Title: Testosterone regulates RhoA/Rho-kinase signaling in two distinct animal models of chemical diabetes.
Journal: The journal of sexual medicine 20070501
Title: Small GTPase Rho signaling is involved in beta1 integrin-mediated up-regulation of intercellular adhesion molecule 1 and receptor activator of nuclear factor kappaB ligand on osteoblasts and osteoclast maturation.
Journal: Biochemical and biophysical research communications 20070427
Title: Oxygen activates the Rho/Rho-kinase pathway and induces RhoB and ROCK-1 expression in human and rabbit ductus arteriosus by increasing mitochondria-derived reactive oxygen species: a newly recognized mechanism for sustaining ductal constriction.
Journal: Circulation 20070403
Title: Oxytocin-induced phasic and tonic contractions are modulated by the contractile machinery rather than the quantity of oxytocin receptor.
Journal: American journal of physiology. Endocrinology and metabolism 20070401
Title: Collagen gel contractility is enhanced in human endometriotic stromal cells: a possible mechanism underlying the pathogenesis of endometriosis-associated fibrosis.
Journal: Human reproduction (Oxford, England) 20070401
Title: Hypotonicity causes actin reorganization and recruitment of the actin-binding ERM protein moesin in membrane protrusions in collecting duct principal cells.
Journal: American journal of physiology. Cell physiology 20070401
Title: RhoA/Rho kinase up-regulate Bax to activate a mitochondrial death pathway and induce cardiomyocyte apoptosis.
Journal: The Journal of biological chemistry 20070316
Title: Role of Rho kinases in PKG-mediated relaxation of pulmonary arteries of fetal lambs exposed to chronic high altitude hypoxia.
Journal: American journal of physiology. Lung cellular and molecular physiology 20070301
Title: Organized migration of epithelial cells requires control of adhesion and protrusion through Rho kinase effectors.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20070301
Title: Inhibition of RhoA/Rho-kinase pathway suppresses the expression of type I collagen induced by TGF-beta2 in human retinal pigment epithelial cells.
Journal: Experimental eye research 20070301
Title: Involvement of nuclear factor-kB activation through RhoA/Rho-kinase pathway in LPS-induced IL-8 production in human cervical stromal cells.
Journal: Molecular human reproduction 20070301
Title: Dermal condensation formation in the chick embryo: requirement for integrin engagement and subsequent stabilization by a possible notch/integrin interaction.
Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20070301
Title: Reduced contractile response to alpha1-adrenergic stimulation in atria from mice with chronic cardiac calmodulin kinase II inhibition.
Journal: Journal of molecular and cellular cardiology 20070301
Title: Direct effects of hydrogen peroxide on airway smooth muscle tone: roles of Ca2+ influx and Rho-kinase.
Journal: European journal of pharmacology 20070205
Title: Both Ca2+ -dependent and -independent pathways are involved in rat hepatic stellate cell contraction and intrahepatic hyperresponsiveness to methoxamine.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20070201
Title: Involvement of microtubules, p38, and Rho kinases pathway in 2-methoxyestradiol-induced lung vascular barrier dysfunction.
Journal: American journal of physiology. Lung cellular and molecular physiology 20070201
Title: Pressor response induced by central angiotensin II is mediated by activation of Rho/Rho-kinase pathway via AT1 receptors.
Journal: Journal of hypertension 20070201
Title: Rho-associated kinase inhibitor reduces tumor recurrence after liver transplantation in a rat hepatoma model.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070201
Title: A role for WASP Interacting Protein, WIP, in fibroblast adhesion, spreading and migration.
Journal: The international journal of biochemistry & cell biology 20070101
Title: Novel Rho kinase inhibitors with anti-inflammatory and vasodilatory activities.
Journal: The Journal of pharmacology and experimental therapeutics 20070101
Title: Cellular mechanisms of mainstream cigarette smoke-induced lung epithelial tight junction permeability changes in vitro.
Journal: Inhalation toxicology 20070101
Title: RhoA activation and interaction with Caveolin-1 are critical for pressure-induced myogenic tone in rat mesenteric resistance arteries.
Journal: Cardiovascular research 20070101
Title: RhoA/Rho kinase-mediated Ca2+ sensitization in the contraction of human prostate.
Journal: Neurourology and urodynamics 20070101
Title: Lysophosphatidic acid stimulation of platelets rapidly induces Ca2+-dependent dephosphorylation of cofilin that is independent of dense granule secretion and aggregation.
Journal: Blood cells, molecules & diseases 20070101
Title: Quantifying myosin light chain phosphorylation in single adherent cells with automated fluorescence microscopy.
Journal: BMC cell biology 20070101
Title: Azithromycin has a direct relaxant effect on precontracted airway smooth muscle.
Journal: European journal of pharmacology 20061228
Title: Roles of stretch-activated cation channel and Rho-kinase in the spontaneous contraction of airway smooth muscle.
Journal: European journal of pharmacology 20061215
Title: Isoprostane-induced airway hyperresponsiveness is dependent on internal Ca2+ handling and Rho/ROCK signaling.
Journal: American journal of physiology. Lung cellular and molecular physiology 20061201
Title: Role of RhoA inactivation in reduced cell proliferation of human airway smooth muscle by simvastatin.
Journal: American journal of respiratory cell and molecular biology 20061201
Title: Non-muscle myosin-II-B filament regulation of paracellular resistance in cervical epithelial cells is associated with modulation of the cortical acto-myosin.
Journal: Journal of the Society for Gynecologic Investigation 20061201
Title: Terbinafine inhibits endothelial cell migration through suppression of the Rho-mediated pathway.
Journal: Molecular cancer therapeutics 20061201
Title: A Rho-kinase inhibitor, Y-27632, reduces cholinergic contraction but not neurotransmitter release.
Journal: European journal of pharmacology 20061121
Title: Rapid stimulation of tyrosine phosphorylation signals downstream of G-protein-coupled receptors for thromboxane A2 in human platelets.
Journal: The Biochemical journal 20061115
Title: Rho kinase activation maintains high pulmonary vascular resistance in the ovine fetal lung.
Journal: American journal of physiology. Lung cellular and molecular physiology 20061101
Title: Cooperation of matrix metalloproteinases with the RhoA/Rho kinase and mitogen-activated protein kinase kinase-1/extracellular signal-regulated kinase signaling pathways is required for the sphingosine-1-phosphate-induced mobilization of marrow-derived stromal cells.
Journal: Stem cells (Dayton, Ohio) 20061101
Title: Hyaluronan induces vascular smooth muscle cell migration through RHAMM-mediated PI3K-dependent Rac activation.
Journal: Cardiovascular research 20061101
Title: Rho-kinase-mediated regulation of receptor-agonist-stimulated smooth muscle contraction.
Journal: Pflugers Archiv : European journal of physiology 20061101
Title: Quantitative assessment of local collagen matrix remodeling in 3-D culture: the role of Rho kinase.
Journal: Experimental cell research 20061101
Title: Changes of Rho kinase activity after hemorrhagic shock and its role in shock-induced biphasic response of vascular reactivity and calcium sensitivity.
Journal: Shock (Augusta, Ga.) 20061101
Title: Rho kinase regulates phagocytosis, surface expression of GlcNAc, and Golgi fragmentation of apoptotic PC12 cells.
Journal: Experimental cell research 20061015
Title: Myosin-based contraction is not necessary for cardiac c-looping in the chick embryo.
Journal: Anatomy and embryology 20061001
Title: Cholesterol modulates the volume-regulated anion current in Ehrlich-Lettre ascites cells via effects on Rho and F-actin.
Journal: American journal of physiology. Cell physiology 20061001
Title: Gabapentin-lactam induces dendritic filopodia and motility in cultured hippocampal neurons.
Journal: The Journal of pharmacology and experimental therapeutics 20061001
Title: Internal mammary artery smooth muscle cells resist migration and possess high antioxidant capacity.
Journal: Cardiovascular research 20061001
Title: Essential role of Rho/ROCK-dependent processes and actin dynamics in mediating leptin-induced hypertrophy in rat neonatal ventricular myocytes.
Journal: Cardiovascular research 20061001
Title: Ovariectomy augments hypertension through rho-kinase activation in the brain stem in female spontaneously hypertensive rats.
Journal: Hypertension (Dallas, Tex. : 1979) 20061001
Title: Role of megakaryoblastic acute leukemia-1 in ERK1/2-dependent stimulation of serum response factor-driven transcription by BDNF or increased synaptic activity.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060927
Title: Mechanical stretch has contrasting effects on mediator release from bronchial epithelial cells, with a rho-kinase-dependent component to the mechanotransduction pathway.
Journal: Respiratory medicine 20060901
Title: Intracellular signal transduction for migration and actin remodeling in vascular smooth muscle cells after sphingosylphosphorylcholine stimulation.
Journal: American journal of physiology. Heart and circulatory physiology 20060901
Title: HMG-CoA reductase inhibitor fluvastatin prevents angiotensin II-induced cardiac hypertrophy via Rho kinase and inhibition of cyclin D1.
Journal: Life sciences 20060829
Title: Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity.
Journal: The Journal of biological chemistry 20060825
Title: Thrombin-induced contraction in alveolar epithelial cells probed by traction microscopy.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20060801
Title: Chronic fluvastatin treatment alters vascular contraction by inhibiting the Rho/Rho-kinase pathway.
Journal: Clinical and experimental pharmacology & physiology 20060801
Title: Rho-kinase inhibitor, Y-27632, has an antinociceptive effect in mice.
Journal: European journal of pharmacology 20060710
Title: Statins revert doxorubicin resistance via nitric oxide in malignant mesothelioma.
Journal: International journal of cancer 20060701
Title: Increased RhoA/Rho-kinase signaling mediates spontaneous tone in aorta from angiotensin II-induced hypertensive rats.
Journal: The Journal of pharmacology and experimental therapeutics 20060701
Title: Imaging macrophage chemotaxis in vivo: studies of microtubule function in zebrafish wound inflammation.
Journal: Cell motility and the cytoskeleton 20060701
Title: Contribution of Rho-kinase in human gallbladder contractions.
Journal: European journal of pharmacology 20060701
Title: Reduction of tissue plasminogen activator-induced matrix metalloproteinase-9 by simvastatin in astrocytes.
Journal: Stroke 20060701
Title: Synergistic effects of CoCl(2) and ROCK inhibition on mesenchymal stem cell differentiation into neuron-like cells.
Journal: Journal of cell science 20060701
Title: The role of the RhoA/Rho-kinase signaling pathway in renal vascular reactivity in endothelial nitric oxide synthase null mice.
Journal: Journal of hypertension 20060701
Title: An MLCK-dependent window in late G1 controls S phase entry of proliferating rodent hepatocytes via ERK-p70S6K pathway.
Journal: Hepatology (Baltimore, Md.) 20060701
Title: Rho A/Rho kinase: human umbilical artery mRNA expression in normal and pre eclamptic pregnancies and functional role in isoprostane-induced vasoconstriction.
Journal: Reproduction (Cambridge, England) 20060701
Title: Rho-kinase contributes to hypoxia/reoxygenation-induced cerebral endothelial dysfunction.
Journal: Journal of cardiovascular pharmacology 20060701
Title: Phosphoryl transfer is not rate-limiting for the ROCK I-catalyzed kinase reaction.
Journal: Biochemistry 20060627
Title: Effect of doxazosin with and without rho-kinase inhibitor on human corpus cavernosum smooth muscle in the presence of bladder outlet obstruction.
Journal: The Journal of urology 20060601
Title: Myosin light chain kinase plays a role in the regulation of epithelial cell survival.
Journal: Journal of cell science 20060601
Title: Actomyosin tension is required for correct recruitment of adherens junction components and zonula occludens formation.
Journal: Experimental cell research 20060515
Title: Protective effect of fasudil, a Rho-kinase inhibitor, on chemokine expression, leukocyte recruitment, and hepatocellular apoptosis in septic liver injury.
Journal: Journal of leukocyte biology 20060501
Title: A role for Rho kinase in vascular contraction evoked by sodium fluoride.
Journal: Biochemical and biophysical research communications 20060428
Title: Involvement of Rho signaling in PAR2-mediated regulation of neutrophil adhesion to lung epithelial cells.
Journal: European journal of pharmacology 20060424
Title: Tubuloglomerular feedback-dependent modulation of renal myogenic autoregulation by nitric oxide.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20060401
Title: Differential Rho-kinase dependency of full and partial muscarinic receptor agonists in airway smooth muscle contraction.
Journal: British journal of pharmacology 20060401
Title: Augmented sphingosylphosphorylcholine-induced Ca2+-sensitization of mesenteric artery contraction in spontaneously hypertensive rat.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20060401
Title: Sphingosine-1-phosphate modulates spiral modiolar artery tone: A potential role in vascular-based inner ear pathologies?
Journal: Cardiovascular research 20060401
Title: Attenuation of contractility in rat epididymal vas deferens by Rho kinase inhibitors.
Journal: Autonomic & autacoid pharmacology 20060401
Title: Lack of interaction between prostaglandin E2 receptor subtypes in regulating adenylyl cyclase activity in cultured rat dorsal root ganglion cells.
Journal: European journal of pharmacology 20060327
Title: Stretch-induced triphosphorylation of myosin light chain and myogenic tone in canine basilar artery.
Journal: European journal of pharmacology 20060318
Title: Role of Rho-kinase in guinea-pig gallbladder smooth muscle contraction.
Journal: European journal of pharmacology 20060318
Title: Rho-associated protein kinase inhibitor, Y-27632, induces alterations in adhesion, contraction and motility in cultured human trabecular meshwork cells.
Journal: Experimental eye research 20060301
Title: Increased basal phosphorylation of detrusor smooth muscle myosin in alloxan-induced diabetic rabbit is mediated by upregulation of Rho-kinase beta and CPI-17.
Journal: American journal of physiology. Renal physiology 20060301
Title: The role of Rho-associated kinase in differential regulation by statins of interleukin-1beta- and lipopolysaccharide-mediated nuclear factor kappaB activation and inducible nitric-oxide synthase gene expression in vascular smooth muscle cells.
Journal: Molecular pharmacology 20060301
Title: Pregnancy-induced modulation of calcium mobilization and down-regulation of Rho-kinase expression contribute to attenuated vasopressin-induced contraction of the rat aorta.
Journal: Vascular pharmacology 20060301
Title: Centaureidin promotes dendrite retraction of melanocytes by activating Rho.
Journal: Biochimica et biophysica acta 20060301
Title: Heat shock-induced augmentation of vascular contractility is independent of rho-kinase.
Journal: Clinical and experimental pharmacology & physiology 20060301
Title: Intrahepatic flow disturbance: possibility of a hidden cause of drug toxicity.
Journal: Journal of pharmacological sciences 20060301
Title: Defective RhoA/Rho-kinase signaling contributes to vascular hypocontractility and vasodilation in cirrhotic rats.
Journal: Gastroenterology 20060301
Title: Developmental regulation of nerve and receptor mediated contractions of mammalian urinary bladder smooth muscle.
Journal: European journal of pharmacology 20060217
Title: Deficient E-cadherin adhesion in C57BL/6J-Min/+ mice is associated with increased tyrosine kinase activity and RhoA-dependent actomyosin contractility.
Journal: Experimental cell research 20060215
Title: Inhibition of Rho-kinase normalizes nonspecific hyperresponsiveness in passively sensitized airway smooth muscle preparations.
Journal: European journal of pharmacology 20060215
Title: Involvement of rho kinase in the ouabain-induced contractions of the rat renal arteries.
Journal: Biochemical and biophysical research communications 20060210
Title: Mechanisms of endothelin-1-induced contraction in pulmonary arteries from chronically hypoxic rats.
Journal: American journal of physiology. Lung cellular and molecular physiology 20060201
Title: Involvement of ROCK-mediated endothelial tension development in neutrophil-stimulated microvascular leakage.
Journal: American journal of physiology. Heart and circulatory physiology 20060201
Title: M2 and M3 muscarinic receptor activation of urinary bladder contractile signal transduction. I. Normal rat bladder.
Journal: The Journal of pharmacology and experimental therapeutics 20060201
Title: M2 and M3 muscarinic receptor activation of urinary bladder contractile signal transduction. II. Denervated rat bladder.
Journal: The Journal of pharmacology and experimental therapeutics 20060201
Title: Up-regulation of CPI-17 phosphorylation in diabetic vasculature and high glucose cultured vascular smooth muscle cells.
Journal: Cardiovascular research 20060201
Title: Rho/ROCK pathway as a target of tumor therapy.
Journal: Journal of neuroscience research 20060201
Title: Involvement of reduced sensitivity to Ca in beta-adrenergic action on airway smooth muscle.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20060201
Title: The structure of dimeric ROCK I reveals the mechanism for ligand selectivity.
Journal: The Journal of biological chemistry 20060106
Title: Enhanced role for RhoA-associated kinase in adrenergic-mediated vasoconstriction in gracilis arteries from obese Zucker rats.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20060101
Title: Role of protein kinases in mediating diabetes-induced augmented vasoconstriction to endothelin-1 in the renal arteries of STZ-diabetic rats.
Journal: Cell biochemistry and function 20060101
Title: RhoA- and PKC-alpha-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20060101
Title: Rho kinase regulates fragmentation and phagocytosis of apoptotic cells.
Journal: Experimental cell research 20060101
Title: Effects of calpain and Rho-kinase inhibitors on the acrosome reaction and motility of fowl spermatozoa in vitro.
Journal: Reproduction (Cambridge, England) 20060101
Title: Mechanism of increased alpha-adrenoceptor-mediated contraction in small resistance arteries of rats with heart failure.
Journal: Clinical and experimental pharmacology & physiology 20060101
Title: Expression, purification, and characterization of an enzymatically active truncated human rho-kinase I (ROCK I) domain expressed in Sf-9 insect cells.
Journal: Protein and peptide letters 20060101
Title: Contraction of myofibroblasts in granulation tissue is dependent on Rho/Rho kinase/myosin light chain phosphatase activity.
Journal: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20060101
Title: Direct Rho-associated kinase inhibition [correction of inhibiton] induces cofilin dephosphorylation and neurite outgrowth in PC-12 cells.
Journal: Cellular & molecular biology letters 20060101
Title: Inhalation of the Rho-kinase inhibitor Y-27632 reverses allergen-induced airway hyperresponsiveness after the early and late asthmatic reaction.
Journal: Respiratory research 20060101
Title: Rho kinase expression and its central role in ovine gallbladder contractions elicited by a variety of excitatory stimuli.
Journal: European journal of pharmacology 20051228
Title: 5-Hydroxytryptamine as a potent migration enhancer of human aortic endothelial cells.
Journal: FEBS letters 20051219
Title: Lysophosphatidic acid induces histamine release from mast cells and skin fragments.
Journal: Pharmacology 20051201
Title: Role of Rho-kinase in reexpansion pulmonary edema in rabbits.
Journal: American journal of physiology. Lung cellular and molecular physiology 20051201
Title: Constrictor-induced translocation of NFAT3 in human and rat pulmonary artery smooth muscle.
Journal: American journal of physiology. Lung cellular and molecular physiology 20051201
Title: Role of Rho GTPase in astrocyte morphology and migratory response during in vitro wound healing.
Journal: Journal of neurochemistry 20051201
Title: Dose-dependent beneficial and detrimental effects of ROCK inhibitor Y27632 on axonal sprouting and functional recovery after rat spinal cord injury.
Journal: Experimental neurology 20051201
Title: [The role of specific ROCK inhibitor in the prevention of experimental PVR in rabbits].
Journal: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20051201
Title: Relative contribution of Rho kinase and protein kinase C to myogenic tone in rat cerebral arteries in hypertension.
Journal: American journal of physiology. Heart and circulatory physiology 20051101
Title: Rho kinase inhibitors reduce neurally evoked contraction of the rat tail artery in vitro.
Journal: British journal of pharmacology 20051101
Title: Inhibition of the RhoA/Rho kinase system attenuates catecholamine biosynthesis in PC 12 rat pheochromocytoma cells.
Journal: Biochimica et biophysica acta 20051030
Title: Inhibition of iNOS gene expression by quercetin is mediated by the inhibition of IkappaB kinase, nuclear factor-kappa B and STAT1, and depends on heme oxygenase-1 induction in mouse BV-2 microglia.
Journal: European journal of pharmacology 20051003
Title: Sphingosylphosphorylcholine-induced vasoconstriction of pulmonary artery: activation of non-store-operated Ca2+ entry.
Journal: Cardiovascular research 20051001
Title: 5,6-EET-induced contraction of intralobar pulmonary arteries depends on the activation of Rho-kinase.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20051001
Title: Proerectile effects of the Rho-kinase inhibitor (S)-(+)-2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]homopiperazine (H-1152) in the rat penis.
Journal: The Journal of pharmacology and experimental therapeutics 20051001
Title: Myosin 2 is a key Rho kinase target necessary for the local concentration of E-cadherin at cell-cell contacts.
Journal: Molecular biology of the cell 20051001
Title: Okadaic acid induces phosphorylation and translocation of myosin phosphatase target subunit 1 influencing myosin phosphorylation, stress fiber assembly and cell migration in HepG2 cells.
Journal: Cellular signalling 20051001
Title: Non-capacitative calcium entry--extension of the possibilities for calcium entry in vascular tissue.
Journal: Cardiovascular research 20051001
Title: Inhibition of Rho kinase (ROCK) leads to increased cerebral blood flow and stroke protection.
Journal: Stroke 20051001
Title: Expression and functional role of the RhoA/Rho-kinase pathway in rat coeliac artery.
Journal: Clinical and experimental pharmacology & physiology 20051001
Title: Cooling-induced contraction of the rat gastric fundus: mediation via transient receptor potential (TRP) cation channel TRPM8 receptor and Rho-kinase activation.
Journal: Clinical and experimental pharmacology & physiology 20051001
Title: Inhibition of Rho-kinase affects astrocytoma morphology, motility, and invasion through activation of Rac1.
Journal: Cancer research 20051001
Title: Redundant mechanisms for anaphase chromosome movements: crane-fly spermatocyte spindles normally use actin filaments but also can function without them.
Journal: Protoplasma 20051001
Title: A key role for Abl family kinases in EphA receptor-mediated growth cone collapse.
Journal: Molecular and cellular neurosciences 20050901
Title: Active relocation of chromatin and endoplasmic reticulum into blebs in late apoptotic cells.
Journal: Journal of cell science 20050901
Title: Multiple signaling pathways are activated during insulin-like growth factor-I (IGF-I) stimulated breast cancer cell migration.
Journal: Breast cancer research and treatment 20050901
Title: PHI-1 induced enhancement of myosin phosphorylation in chicken smooth muscle.
Journal: FEBS letters 20050815
Title: RhoA-Rho kinase pathway mediates thrombin- and U-46619-induced phosphorylation of a myosin phosphatase inhibitor, CPI-17, in vascular smooth muscle cells.
Journal: American journal of physiology. Cell physiology 20050801
Title: Simvastatin inhibits NOR-1 expression induced by hyperlipemia by interfering with CREB activation.
Journal: Cardiovascular research 20050801
Title: Inhibition of rho-kinase in the nucleus tractus solitarius enhances glutamate sensitivity in rats.
Journal: Hypertension (Dallas, Tex. : 1979) 20050801
Title: Intrathecal administration of Y-27632, a specific rho-associated kinase inhibitor, for rat neoplastic meningitis.
Journal: Molecular cancer research : MCR 20050801
Title: Cdc42 contributes to phorbol ester-induced Ca2+-independent contraction of pulmonary artery smooth muscle.
Journal: The Journal of veterinary medical science 20050801
Title: Endothelin-1-induced translocation of RhoA is mediated by endothelin ET(A) receptors in rat bronchial smooth muscle.
Journal: European journal of pharmacology 20050711
Title: ROK-induced cross-link formation stiffens passive muscle: reversible strain-induced stress softening in rabbit detrusor.
Journal: American journal of physiology. Cell physiology 20050701
Title: Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1.
Journal: The Journal of biological chemistry 20050701
Title: Regulation of vascular tone from spontaneously hypertensive rats by the HMG-CoA reductase inhibitor, simvastatin.
Journal: Pharmacology 20050701
Title: Thrombin modulates the expression of a set of genes including thrombospondin-1 in human microvascular endothelial cells.
Journal: The Journal of biological chemistry 20050610
Title: Attenuation of endotoxin-induced acute lung injury by the Rho-associated kinase inhibitor, Y-27632.
Journal: American journal of respiratory cell and molecular biology 20050601
Title: Effects of ML-7 and Y-27632 on carbachol- and endothelin-1-induced contraction of bovine trabecular meshwork.
Journal: Experimental eye research 20050601
Title: Trapidil inhibits platelet-derived growth factor-induced migration via protein kinase A and RhoA/Rho-associated kinase in rat vascular smooth muscle cells.
Journal: European journal of pharmacology 20050516
Title: Mitogen-activated protein kinase contributes to elevated basal tone in aortic smooth muscle from hypertensive rats.
Journal: European journal of pharmacology 20050509
Title: Simvastatin inhibits MMP-9 secretion from human saphenous vein smooth muscle cells by inhibiting the RhoA/ROCK pathway and reducing MMP-9 mRNA levels.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050501
Title: Contractile properties of the cultured vascular smooth muscle cells: the crucial role played by RhoA in the regulation of contractility.
Journal: Circulation research 20050429
Title: Activation of protease-activated receptor-1 triggers astrogliosis after brain injury.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050427
Title: Statins potentiate the IFN-gamma-induced upregulation of group IIA phospholipase A2 in human aortic smooth muscle cells and HepG2 hepatoma cells.
Journal: Biochimica et biophysica acta 20050415
Title: Simvastatin attenuates expression of cytokine-inducible nitric-oxide synthase in embryonic cardiac myoblasts.
Journal: The Journal of biological chemistry 20050408
Title: Postnatal maturational shift from PKCzeta and voltage-gated K+ channels to RhoA/Rho kinase in pulmonary vasoconstriction.
Journal: Cardiovascular research 20050401
Title: Rho-kinase (ROCK-1 and ROCK-2) upregulation in oleic acid-induced lung injury and its restoration by Y-27632.
Journal: European journal of pharmacology 20050307
Title: Inhaled Rho kinase inhibitors are potent and selective vasodilators in rat pulmonary hypertension.
Journal: American journal of respiratory and critical care medicine 20050301
Title: Small guanine nucleotide-binding protein Rho and myocardial function.
Journal: Acta pharmacologica Sinica 20050301
Title: Tocolytic effect of a Rho-kinase inhibitor in a mouse model of lipopolysaccharide-induced preterm delivery.
Journal: American journal of obstetrics and gynecology 20050301
Title: Screening for cell migration inhibitors via automated microscopy reveals a Rho-kinase inhibitor.
Journal: Chemistry & biology 20050301
Title: Myosin light chain kinase and Rho-kinase participate in P2Y receptor-mediated acceleration of permeability through the endothelial cell layer.
Journal: The Journal of pharmacy and pharmacology 20050301
Title: Differential inhibition by the Rho kinase inhibitor Y-27632 of the increases in contractility and Ca2+ transients induced by endothelin-1 in rabbit ventricular myocytes.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20050301
Title: Age-dependent enhancement of hippocampal long-term potentiation and impairment of spatial learning through the Rho-associated kinase pathway in protein tyrosine phosphatase receptor type Z-deficient mice.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050202
Title: RhoA and Rho-kinase dependent and independent signals mediate TGF-beta-induced pulmonary endothelial cytoskeletal reorganization and permeability.
Journal: American journal of physiology. Lung cellular and molecular physiology 20050201
Title: Two G protein-coupled receptors activate Na+/H+ exchanger isoform 1 in Chinese hamster lung fibroblasts through an ERK-dependent pathway.
Journal: Cellular signalling 20050201
Title: Impaired endothelium-dependent responses and enhanced influence of Rho-kinase in cerebral arterioles in type II diabetes.
Journal: Stroke 20050201
Title: Effects of the Rho kinase inhibitor Y-27632 and the phosphatase inhibitor calyculin A on outflow facility in monkeys.
Journal: Experimental eye research 20050201
Title: Rho-kinase and myosin II activities are required for cell type and environment specific migration.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20050201
Title: Inhibition of Rho-kinase stimulates nitric oxide-independent vasorelaxation.
Journal: European journal of pharmacology 20050110
Title: Extracellular signal-regulated kinase1/2 in contraction of vascular smooth muscle.
Journal: Life sciences 20050107
Title: Effects of Y-27632, a selective Rho-kinase inhibitor, on myocardial preconditioning in anesthetized rats.
Journal: Biochemical pharmacology 20050101
Title: Key role of myosin light chain (MLC) kinase-mediated MLC2a phosphorylation in the alpha 1-adrenergic positive inotropic effect in human atrium.
Journal: Cardiovascular research 20050101
Title: Interactive role of protein kinase C-delta with rho-kinase in the development of cerebral vasospasm in a canine two-hemorrhage model.
Journal: Journal of vascular research 20050101
Title: Cardioprotective mechanisms of Rho-kinase inhibition associated with eNOS and oxidative stress-LOX-1 pathway in Dahl salt-sensitive hypertensive rats.
Journal: Journal of hypertension 20050101
Title: Attenuated noradrenaline-induced contraction of pulmonary arteries from rats treated with monocrotaline: role of rho kinase.
Journal: Journal of vascular research 20050101
Title: The integrin-linked kinase regulates cell morphology and motility in a rho-associated kinase-dependent manner.
Journal: The Journal of biological chemistry 20041224
Title: RhoA and Rac1 are both required for efficient wound closure of airway epithelial cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20041201
Title: Vasoconstrictor mechanisms in the cerebral circulation are unaffected by insulin resistance.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20041201
Title: Rho-kinase inhibition enhances axonal plasticity and attenuates cold hyperalgesia after dorsal rhizotomy.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20041201
Title: N-cadherin juxtamembrane domain modulates voltage-gated Ca2+ current via RhoA GTPase and Rho-associated kinase.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20041201
Title: Inactivation of Rho/ROCK signaling is crucial for the nuclear accumulation of FKHR and myoblast fusion.
Journal: The Journal of biological chemistry 20041105
Title: The role of Rho kinase and extracellular regulated kinase-mitogen-activated protein kinase in alpha2-adrenoceptor-mediated vasoconstriction in the porcine palmar lateral vein.
Journal: The Journal of pharmacology and experimental therapeutics 20041101
Title: Differential regulation of human lung epithelial and endothelial barrier function by thrombin.
Journal: American journal of respiratory cell and molecular biology 20041101
Title: HMG-CoA reductase inhibitors up-regulate anti-aging klotho mRNA via RhoA inactivation in IMCD3 cells.
Journal: Cardiovascular research 20041101
Title: The permeability-reducing effects of prostacyclin and inhibition of Rho kinase do not counteract endotoxin-induced increase in permeability in cat skeletal muscle.
Journal: Microvascular research 20041101
Title: Differential interplay between protein kinase C and Rho-kinase in the endothelin-1-induced and pressure-induced contractions of rat posterior cerebral artery.
Journal: Journal of cardiovascular pharmacology 20041101
Title: Cell type-specific regulation of RhoA activity during cytokinesis.
Journal: The Journal of biological chemistry 20041022
Title: Rho/ROCK and Cdk5 effects on phosphorylation of a beta-thymosin repeat protein in Hermissenda.
Journal: Biochemical and biophysical research communications 20041015
Title: Sphingosine 1-phosphate stimulates smooth muscle cell differentiation and proliferation by activating separate serum response factor co-factors.
Journal: The Journal of biological chemistry 20041008
Title: Rho/Rho kinase signaling mediates increased basal pulmonary vascular tone in chronically hypoxic rats.
Journal: American journal of physiology. Lung cellular and molecular physiology 20041001
Title: Effect of changes in pH on wall tension in isolated rat pulmonary artery: role of the RhoA/Rho-kinase pathway.
Journal: American journal of physiology. Lung cellular and molecular physiology 20041001
Title: 8-Bromo-cAMP decreases the Ca2+ sensitivity of airway smooth muscle contraction through a mechanism distinct from inhibition of Rho-kinase.
Journal: American journal of physiology. Lung cellular and molecular physiology 20041001
Title: KCl evokes contraction of airway smooth muscle via activation of RhoA and Rho-kinase.
Journal: American journal of physiology. Lung cellular and molecular physiology 20041001
Title: Microtubule disassembly induces cytoskeletal remodeling and lung vascular barrier dysfunction: role of Rho-dependent mechanisms.
Journal: Journal of cellular physiology 20041001
Title: Expression of Rho-kinase (ROCK-1 and ROCK-2) and its substantial role in the contractile activity of the sheep ureter.
Journal: British journal of pharmacology 20041001
Title: Activation of Rho/Rho kinase signaling pathway by reactive oxygen species in rat aorta.
Journal: American journal of physiology. Heart and circulatory physiology 20041001
Title: [Role of ROK in contraction of rat femoral arteries after 14 d tail suspension].
Journal: Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering 20041001
Title: Abl tyrosine kinase promotes dendrogenesis by inducing actin cytoskeletal rearrangements in cooperation with Rho family small GTPases in hippocampal neurons.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040929
Title: A role for hippocampal Rho-ROCK pathway in long-term spatial memory.
Journal: Biochemical and biophysical research communications 20040924
Title: Rho kinase-induced nuclear translocation of ERK1/ERK2 in smooth muscle cell mitogenesis caused by serotonin.
Journal: Circulation research 20040917
Title: Upregulation of Rho-kinase (ROCK-2) expression and enhanced contraction to endothelin-1 in the mesenteric artery from lipopolysaccharide-treated rats.
Journal: European journal of pharmacology 20040913
Title: Aggregation of integrins and RhoA activation are required for Thy-1-induced morphological changes in astrocytes.
Journal: The Journal of biological chemistry 20040910
Title: Regulation of vascular endothelial growth factor receptor 2-mediated phosphorylation of focal adhesion kinase by heat shock protein 90 and Src kinase activities.
Journal: The Journal of biological chemistry 20040910
Title: Evidence that estrogen suppresses rho-kinase function in the cerebral circulation in vivo.
Journal: Stroke 20040901
Title: Itch-scratch responses induced by lysophosphatidic acid in mice.
Journal: Pharmacology 20040901
Title: Investigation of signaling pathways that mediate the inotropic effect of urotensin-II in human heart.
Journal: Cardiovascular research 20040901
Title: Mechanisms of neurokinin A- and substance P-induced contractions in rat detrusor smooth muscle in vitro.
Journal: BJU international 20040901
Title: The small GTPase Rac is involved in clustering of hippocampal neurons and fasciculation of their neurites.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20040901
Title: Stretch of the vascular wall induces smooth muscle differentiation by promoting actin polymerization.
Journal: The Journal of biological chemistry 20040813
Title: Role of adhesion and contraction in Rac 1-regulated endothelial barrier function in vivo and in vitro.
Journal: American journal of physiology. Heart and circulatory physiology 20040801
Title: Unique morphology and focal adhesion development of valvular endothelial cells in static and fluid flow environments.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20040801
Title: Chronic mevastatin modulates receptor-dependent vascular contraction in eNOS-deficient mice.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20040801
Title: Ca2+ sensitization in contraction of human bladder smooth muscle.
Journal: The Journal of urology 20040801
Title: Vanadate activates Rho A translocation in association with contracting effects in ileal longitudinal smooth muscle of guinea pig.
Journal: Journal of pharmacological sciences 20040801
Title: Actions downstream of cyclic GMP/protein kinase G can reverse protein kinase C-mediated phosphorylation of CPI-17 and Ca²⁺ sensitization in smooth muscle.
Journal: The Journal of biological chemistry 20040709
Title: Pressor responses to platelet-activating factor and thromboxane are mediated by Rho-kinase.
Journal: American journal of physiology. Lung cellular and molecular physiology 20040701
Title: An essential role of Cav1.2 L-type calcium channel for urinary bladder function.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040701
Title: Differential effects of simvastatin on mesangial cells.
Journal: Kidney international 20040701
Title: P-cresol, a uremic retention solute, alters the endothelial barrier function in vitro.
Journal: Thrombosis and haemostasis 20040701
Title: Controlled pseudopod extension of human neutrophils stimulated with different chemoattractants.
Journal: Biophysical journal 20040701
Title: CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion.
Journal: The Journal of biological chemistry 20040625
Title: Growth factor-induced contraction of human bronchial smooth muscle is Rho-kinase-dependent.
Journal: European journal of pharmacology 20040621
Title: Partial protective effect of Y-27632, a Rho kinase inhibitor, against hepatic ischemia-reperfusion injury in rats.
Journal: European journal of pharmacology 20040616
Title: Atorvastatin completely inhibits VEGF-induced ACE upregulation in human endothelial cells.
Journal: American journal of physiology. Heart and circulatory physiology 20040601
Title: Rho/Rho kinase and phosphoinositide 3-kinase are parallel pathways in the development of spontaneous arterial tone in deoxycorticosterone acetate-salt hypertension.
Journal: The Journal of pharmacology and experimental therapeutics 20040601
Title: The nucleotide receptor P2X7 mediates actin reorganization and membrane blebbing in RAW 264.7 macrophages via p38 MAP kinase and Rho.
Journal: Journal of leukocyte biology 20040601
Title: Mechanisms involved in carbachol-induced Ca(2+) sensitization of contractile elements in rat proximal and distal colon.
Journal: British journal of pharmacology 20040601
Title: Angiotensin II-induced vascular dysfunction is mediated by the AT1A receptor in mice.
Journal: Hypertension (Dallas, Tex. : 1979) 20040501
Title: Female pig urethral tone is dependent on Rho guanosine triphosphatases and Rho-associated kinase.
Journal: The Journal of urology 20040501
Title: Role of ERK and Rho kinase pathways in central pressor action of urotensin II.
Journal: Journal of hypertension 20040501
Title: GIT1 mediates thrombin signaling in endothelial cells: role in turnover of RhoA-type focal adhesions.
Journal: Circulation research 20040430
Title: Endothelial dysfunction and altered bradykinin response due to oxidative stress induced by serum deprivation in the bovine cerebral artery.
Journal: European journal of pharmacology 20040426
Title: Length control is determined by the pattern of cytoskeleton.
Journal: Journal of cell science 20040415
Title: Regulation of osteoblast differentiation by Pasteurella multocida toxin (PMT): a role for Rho GTPase in bone formation.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20040401
Title: Development of a microplate bioassay for monocyte chemoattractant protein-1 based on activation of p44/42 mitogen-activated protein kinase.
Journal: Analytical biochemistry 20040401
Title: The role of the cytoskeleton in cellular adhesion molecule expression in tumor necrosis factor-stimulated endothelial cells.
Journal: Journal of cellular biochemistry 20040401
Title: Phosphodiesterase-5 inhibition synergizes rho-kinase antagonism and enhances erectile response in male hypertensive rats.
Journal: International journal of impotence research 20040401
Title: Rho kinase inhibition initiates apoptosis in human airway epithelial cells.
Journal: American journal of respiratory cell and molecular biology 20040301
Title: Pyrimidine nucleotides suppress KDR currents and depolarize rat cerebral arteries by activating Rho kinase.
Journal: American journal of physiology. Heart and circulatory physiology 20040301
Title: Involvement of RhoA and Rho kinase in neutrophil-stimulated endothelial hyperpermeability.
Journal: American journal of physiology. Heart and circulatory physiology 20040301
Title: Characterization of G proteins involved in activation of nonselective cation channels and arachidonic acid release by norepinephrine/alpha1A-adrenergic receptors.
Journal: American journal of physiology. Cell physiology 20040301
Title: ROCK inhibitor (Y27632) increases apoptosis and disrupts the actin cortical mat in embryonic avian corneal epithelium.
Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20040301
Title: [Involvement of small GTPase Rho and Rho-kinase in the pathogenesis of hypertension and hypertensive target organ damage].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20040301
Title: HSP27 regulates fibroblast adhesion, motility, and matrix contraction.
Journal: Cell stress & chaperones 20040301
Title: The apolipoprotein(a) component of lipoprotein(a) stimulates actin stress fiber formation and loss of cell-cell contact in cultured endothelial cells.
Journal: The Journal of biological chemistry 20040220
Title: A role of activated Sonic hedgehog signaling for the cellular proliferation of oral squamous cell carcinoma cell line.
Journal: Biochemical and biophysical research communications 20040206
Title: Rho-kinase expression and its contribution to the control of perfusion pressure in the isolated rat mesenteric vascular bed.
Journal: European journal of pharmacology 20040206
Title: High glucose-induced upregulation of osteopontin is mediated via Rho/Rho kinase pathway in cultured rat aortic smooth muscle cells.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20040201
Title: Myosin-mediated cytoskeleton contraction and Rho GTPases regulate laminin-5 matrix assembly.
Journal: Cell motility and the cytoskeleton 20040201
Title: Rho/Rho-kinase pathway in the brainstem contributes to hypertension caused by chronic nitric oxide synthase inhibition.
Journal: Hypertension (Dallas, Tex. : 1979) 20040201
Title: Involvement of rho-kinase pathway in contractile activity of rabbit RPE cells in vivo and in vitro.
Journal: Investigative ophthalmology & visual science 20040201
Title: [Rho-kinase inhibitor].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20040201
Title: Enhancement of migration and invasion of hepatoma cells via a Rho GTPase signaling pathway.
Journal: World journal of gastroenterology 20040115
Title: Rho GTPases and phosphoinositide 3-kinase organize formation of branched dendrites.
Journal: The Journal of biological chemistry 20040102
Title: Rho-kinase-mediated Ca2+-independent contraction in rat embryo fibroblasts.
Journal: American journal of physiology. Cell physiology 20040101
Title: Correlation between spontaneous electrical, calcium and mechanical activity in detrusor smooth muscle of the guinea-pig bladder.
Journal: British journal of pharmacology 20040101
Title: Role of Rho-kinase in maintaining airway smooth muscle contractile phenotype.
Journal: European journal of pharmacology 20040101
Title: Induction of neurites by the regulatory domains of PKCdelta and epsilon is counteracted by PKC catalytic activity and by the RhoA pathway.
Journal: Experimental cell research 20040101
Title: The Rho-ROCK system as a new therapeutic target for preventing interstitial fibrosis.
Journal: Drug news & perspectives 20040101
Title: Rho-ROCK signal pathway regulates microtubule-based process formation of cultured podocytes--inhibition of ROCK promoted process elongation.
Journal: Nephron. Experimental nephrology 20040101
Title: Effects of HA-1077 and Y-27632, two rho-kinase inhibitors, in the human umbilical artery.
Journal: Cell biochemistry and biophysics 20040101
Title: Keratinocyte differentiation is regulated by the Rho and ROCK signaling pathway.
Journal: Current biology : CB 20031216
Title: Engulfment of apoptotic cells is negatively regulated by Rho-mediated signaling.
Journal: The Journal of biological chemistry 20031212
Title: Rho kinase inhibitors block activation of pancreatic stellate cells.
Journal: British journal of pharmacology 20031201
Title: Y-27632, a Rho-kinase inhibitor, inhibits proliferation and adrenergic contraction of prostatic smooth muscle cells.
Journal: The Journal of urology 20031201
Title: Role of Rho kinase and actin filament in the increased vascular permeability of skin venules in rats after scalding.
Journal: Burns : journal of the International Society for Burn Injuries 20031201
Title: Edaravone, a radical scavenger, may enhance or produce antiproliferative effects of fluvastatin, amlodipine, ozagrel, GF109203X and Y27632 on cultured basilar artery smooth muscle cells.
Journal: Biological & pharmaceutical bulletin 20031201
Title: Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity.
Journal: Structure (London, England : 1993) 20031201
Title: The role of rho and rho-dependent kinase in serotonin-induced contraction observed in bovine middle cerebral artery.
Journal: The Tohoku journal of experimental medicine 20031201
Title: Nonsteroidal anti-inflammatory drugs can lower amyloidogenic Abeta42 by inhibiting Rho.
Journal: Science (New York, N.Y.) 20031114
Title: Modulation of the expression of connective tissue growth factor by alterations of the cytoskeleton.
Journal: The Journal of biological chemistry 20031107
Title: Involvement of Rho/Rho kinase pathway in regulation of apoptosis in rat hepatic stellate cells.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20031101
Title: Rho inhibition decreases TNF-induced endothelial MAPK activation and monolayer permeability.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20031101
Title: Rho-kinase inhibitor inhibits both myosin phosphorylation-dependent and -independent enhancement of myofilament Ca2+ sensitivity in the bovine middle cerebral artery.
Journal: British journal of pharmacology 20031101
Title: Comparison of effects of Y-27632 and Isoproterenol on release of cytokines from human peripheral T cells.
Journal: International immunopharmacology 20031101
Title: Common signaling pathways link activation of murine PAR-1, LPA, and S1P receptors to proliferation of astrocytes.
Journal: Molecular pharmacology 20031101
Title: Lysophosphatidic acid induces process retraction in CG-4 line oligodendrocytes and oligodendrocyte precursor cells but not in differentiated oligodendrocytes.
Journal: Journal of neurochemistry 20031101
Title: Different migratory and proliferative properties of smooth muscle cells of coronary and femoral artery.
Journal: Atherosclerosis 20031101
Title: Rho-associated protein kinase contributes to early atherosclerotic lesion formation in mice.
Journal: Circulation research 20031031
Title: Enhancement of cisplatin-induced cytotoxicity by ROCK inhibitor through suppression of focal adhesion kinase-independent mechanism in lung carcinoma cells.
Journal: International journal of oncology 20031001
Title: Role of the small GTPase Rho in modulation of the inwardly rectifying potassium channel Kir2.1.
Journal: Molecular pharmacology 20031001
Title: Vasoconstrictor responses, and underlying mechanisms, to isoprostanes in human and porcine bronchial arterial smooth muscle.
Journal: British journal of pharmacology 20031001
Title: Expression of Rho-kinase and its functional role in the contractile activity of the mouse vas deferens.
Journal: British journal of pharmacology 20031001
Title: Novel agents for sexual dysfunction.
Journal: BJU international 20031001
Title: Force and myosin light chain phosphorylation in dog airway smooth muscle activated in different ways.
Journal: Respiratory physiology & neurobiology 20030916
Title: Rho-dependent kinase is involved in agonist-activated calcium entry in rat arteries.
Journal: The Journal of physiology 20030915
Title: ROCK-dependent and ROCK-independent control of cochlear outer hair cell electromotility.
Journal: The Journal of biological chemistry 20030912
Title: Caspase activation during phorbol ester-induced apoptosis requires ROCK-dependent myosin-mediated contraction.
Journal: Journal of cell science 20030901
Title: Sevoflurane inhibits guanosine 5'-[gamma-thio]triphosphate-stimulated, Rho/Rho-kinase-mediated contraction of isolated rat aortic smooth muscle.
Journal: Anesthesiology 20030901
Title: Therapeutic significance of Y-27632, a Rho-kinase inhibitor, on the established liver fibrosis.
Journal: The Journal of surgical research 20030901
Title: Receptor-independent activation of Rho-kinase-mediated calcium sensitisation in smooth muscle.
Journal: British journal of pharmacology 20030802
Title: Erectile physiological and pathophysiological pathways involved in erectile dysfunction.
Journal: The Journal of urology 20030801
Title: Effects of the Rho-kinase inhibitors, Y-27632 and fasudil, on the corpus cavernosum from diabetic mice.
Journal: European journal of pharmacology 20030711
Title: Rho protein-mediated changes in the structure of the actin cytoskeleton regulate human inducible NO synthase gene expression.
Journal: Experimental cell research 20030701
Title: Implication of Rho-associated kinase in the elevation of extracellular dopamine levels and its related behaviors induced by methamphetamine in rats.
Journal: Journal of neurochemistry 20030701
Title: Rho/Rho-kinase pathway in brain stem contributes to blood pressure regulation via sympathetic nervous system: possible involvement in neural mechanisms of hypertension.
Journal: Circulation research 20030627
Title: CCR7 ligands induce rapid endocytosis in mature dendritic cells with concomitant up-regulation of Cdc42 and Rac activities.
Journal: Blood 20030615
Title: Astrocyte stellation induced by Rho kinase inhibitors in culture.
Journal: Brain research. Developmental brain research 20030612
Title: Improved erectile function after Rho-kinase inhibition in a rat castrate model of erectile dysfunction.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20030601
Title: Sertoli-germ cell adherens junction dynamics in the testis are regulated by RhoB GTPase via the ROCK/LIMK signaling pathway.
Journal: Biology of reproduction 20030601
Title: Rho-Rho kinase pathway is involved in the regulation of myogenic tone and pump activity in isolated lymph vessels.
Journal: American journal of physiology. Heart and circulatory physiology 20030601
Title: Variations in cell signaling pathways for different vasoconstrictor agonists in renal circulation of the rat.
Journal: Kidney international 20030601
Title: P2X7 receptor-dependent blebbing and the activation of Rho-effector kinases, caspases, and IL-1 beta release.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030601
Title: Oxidized LDL and its compound lysophosphatidylcholine potentiate AngII-induced vasoconstriction by stimulation of RhoA.
Journal: Journal of the American Society of Nephrology : JASN 20030601
Title: Modulation of Ca2+ sensitivity regulates contractility of rabbit corpus cavernosum smooth muscle.
Journal: The Journal of urology 20030601
Title: Intracellular signal transduction modulating expression of plasminogen activator inhibitor-1 in adipocytes.
Journal: Biochemical pharmacology 20030601
Title: Functional diversity between Rho-kinase- and MLCK-mediated cytoskeletal actions in a myofibroblast-like hepatic stellate cell line.
Journal: Biochemical and biophysical research communications 20030530
Title: Deactivation of ROCK-II by Y-27632 enhances basolateral pancreatic enzyme secretion and acute pancreatitis induced by CCK analogues.
Journal: Biochemical and biophysical research communications 20030530
Title: Rho kinase blockade prevents inflammation via nuclear factor kappa B inhibition: evidence in Crohn's disease and experimental colitis.
Journal: Gastroenterology 20030501
Title: Angiopoietin-1 inhibits endothelial permeability, neutrophil adherence and IL-8 production.
Journal: British journal of pharmacology 20030501
Title: Inhibition of high K+-induced contraction by the ROCKs inhibitor Y-27632 in vascular smooth muscle: possible involvement of ROCKs in a signal transduction pathway.
Journal: Journal of pharmacological sciences 20030501
Title: Functional roles of the rho/rho kinase pathway and protein kinase C in the regulation of cerebrovascular constriction mediated by hemoglobin: relevance to subarachnoid hemorrhage and vasospasm.
Journal: Circulation research 20030418
Title: A novel endocytic pathway induced by clustering endothelial ICAM-1 or PECAM-1.
Journal: Journal of cell science 20030415
Title: RhoA and ROCK promote migration by limiting membrane protrusions.
Journal: The Journal of biological chemistry 20030411
Title: Involvement of Rho/Rho-kinase signalling in the contractile activity and acetylcholine release in the mouse gastric fundus.
Journal: Biochemical and biophysical research communications 20030411
Title: Kinase inhibitors: not just for kinases anymore.
Journal: Journal of medicinal chemistry 20030410
Title: Rapid actin transport during cell protrusion.
Journal: Science (New York, N.Y.) 20030404
Title: Polyamines regulate Rho-kinase and myosin phosphorylation during intestinal epithelial restitution.
Journal: American journal of physiology. Cell physiology 20030401
Title: Sphingosine 1-phosphate induces contraction of coronary artery smooth muscle cells via S1P2.
Journal: Cardiovascular research 20030401
Title: Involvement of Rho-kinase in P2Y-receptor-mediated contraction of renal glomeruli.
Journal: Biochemical and biophysical research communications 20030321
Title: Protein kinase C is necessary for recovery from the thyrotropin-releasing hormone-induced r-ERG current reduction in GH3 rat anterior pituitary cells.
Journal: The Journal of physiology 20030315
Title: Prevention of ischemia-reperfusion-induced hepatic microcirculatory disruption by inhibiting stellate cell contraction using rock inhibitor.
Journal: Transplantation 20030315
Title: Activation of RhoA and inhibition of myosin phosphatase as important components in hypertension in vascular smooth muscle.
Journal: Circulation research 20030307
Title: Rho kinase mediates serum-induced contraction in fibroblast fibers independent of myosin LC20 phosphorylation.
Journal: American journal of physiology. Cell physiology 20030301
Title: Microtubule-disruption-induced and chemotactic-peptide-induced migration of human neutrophils: implications for differential sets of signalling pathways.
Journal: Journal of cell science 20030301
Title: The Rho/ROCK pathway mediates neurite growth-inhibitory activity associated with the chondroitin sulfate proteoglycans of the CNS glial scar.
Journal: Molecular and cellular neurosciences 20030301
Title: Rho kinase inhibition enhances axonal regeneration in the injured CNS.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030215
Title: Independent roles of Rho-GTPases in growth cone and axonal behavior.
Journal: Journal of neurobiology 20030205
Title: Inhibition of Rho-kinase reduces renal Na-H exchanger activity and causes natriuresis in rat.
Journal: The Journal of pharmacology and experimental therapeutics 20030201
Title: Rho kinase and matrix metalloproteinase inhibitors cooperate to inhibit angiogenesis and growth of human prostate cancer xenotransplants.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030201
Title: Phosphorylation of the myosin phosphatase targeting subunit and CPI-17 during Ca2+ sensitization in rabbit smooth muscle.
Journal: The Journal of physiology 20030201
Title: A novel inhibitor of Rho-associated protein kinase, Y-27632, ameliorates hepatic ischemia and reperfusion injury in rats.
Journal: Surgery 20030201
Title: Increased contractility of diabetic rabbit corpora smooth muscle in response to endothelin is mediated via Rho-kinase beta.
Journal: International journal of impotence research 20030201
Title: Cardiovascular effects of Y-27632, a selective Rho-associated kinase inhibitor, assessed in the halothane-anesthetized canine model.
Journal: European journal of pharmacology 20030126
Title: A possible role of RhoA/Rho-kinase in experimental spinal cord injury in rat.
Journal: Brain research 20030103
Title: Rho-kinase inhibition blunts renal vasoconstriction induced by distinct signaling pathways in vivo.
Journal: Journal of the American Society of Nephrology : JASN 20030101
Title: The Rho-kinase inhibitor Y-27632 and the soluble guanylyl cyclase activator BAY41-2272 relax rabbit vaginal wall and clitoral corpus cavernosum.
Journal: British journal of pharmacology 20030101
Title: Inhibition of rho-associated kinase reduces MLC20 phosphorylation and contractility of intact myometrium and attenuates agonist-induced Ca2+ sensitization of force of permeabilized rat myometrium.
Journal: The Journal of veterinary medical science 20030101
Title: Comparison of inhibitory effects of Y-27632, a Rho kinase inhibitor, in strips of small and large mesenteric arteries from spontaneously hypertensive and normotensive Wistar-Kyoto rats.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20030101
Title: Lysophosphatidic acid enhances in vivo infiltration and activation of guinea pig eosinophils and neutrophils via a Rho/Rho-associated protein kinase-mediated pathway.
Journal: Journal of pharmacological sciences 20030101
Title: Rho and p38 MAP kinase signaling pathways mediate LPA-stimulated hepatic myofibroblast migration.
Journal: Journal of biomedical science 20030101
Title: Contribution of Rho A and Rho kinase to platelet-derived growth factor-BB-induced proliferation of vascular smooth muscle cells.
Journal: Journal of atherosclerosis and thrombosis 20030101
Title: Vessel- and vasoconstrictor-dependent role of rho/rho-kinase in renal microvascular tone.
Journal: Journal of vascular research 20030101
Title: RhoA kinase and protein kinase C participate in regulation of rabbit stomach fundus smooth muscle contraction.
Journal: British journal of pharmacology 20021201
Title: Small guanosine triphospatase RhoA and Rho-associated kinase as regulators of trophoblast migration.
Journal: The Journal of clinical endocrinology and metabolism 20021201
Title: Endothelin-1-induced vasospasms of spiral modiolar artery are mediated by rho-kinase-induced Ca(2+) sensitization of contractile apparatus and reversed by calcitonin gene-related Peptide.
Journal: Stroke 20021201
Title: ROCK inhibitor Y-27632 prevents primary graft non-function caused by warm ischemia/reperfusion in rat liver transplantation.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20021201
Title: Role of rho-kinase activity in angiotensin II-induced contraction of rabbit clitoral cavernosum smooth muscle.
Journal: International journal of impotence research 20021201
Title: Beneficial effects of a Rho-associated coiled-coli forming protein serine/threonine kinase inhibitor, Y-27632, on survival of recipients in rat liver transplantation following warm ischemia.
Journal: Transplantation proceedings 20021101
Title: Cerivastatin, a hydroxymethylglutaryl coenzyme A reductase inhibitor, inhibits cardiac myocyte hypertrophy induced by endothelin.
Journal: European journal of pharmacology 20021025
Title: Conventional protein kinase C mediates phorbol-dibutyrate-induced cytoskeletal remodeling in a7r5 smooth muscle cells.
Journal: Experimental cell research 20021015
Title: Translocation of Na(+),K(+)-ATPase is induced by Rho small GTPase in renal epithelial cells.
Journal: Biochemical and biophysical research communications 20021011
Title: Acute and chronic NOS inhibition enhances alpha(2)- adrenoreceptor-stimulated RhoA and Rho kinase in rat aorta.
Journal: American journal of physiology. Heart and circulatory physiology 20021001
Title: Myosin light chain phosphorylation and growth cone motility.
Journal: Journal of neurobiology 20020905
Title: Mechanisms of NOS2 regulation by Rho GTPase signaling in airway epithelial cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20020901
Title: Inhibitory effect of fluvastatin on lysophosphatidylcholine-induced nonselective cation current in Guinea pig ventricular myocytes.
Journal: Molecular pharmacology 20020901
Title: Requirement for RhoA kinase activation in leukocyte de-adhesion.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20020901
Title: Independence of plasma membrane blebbing from other biochemical and biological characteristics of apoptotic cells.
Journal: Journal of biochemistry 20020901
Title: Role of Rho kinase signalling in healthy and varicose human saphenous veins.
Journal: British journal of pharmacology 20020901
Title: Occupation of the prostaglandin E2-type 1 receptor increases rat atrial contractility via a Y-27632-sensitive pathway.
Journal: Prostaglandins & other lipid mediators 20020901
Title: Rho-kinase contributes to diphosphorylation of myosin II regulatory light chain in nonmuscle cells.
Journal: Oncogene 20020829
Title: Rho signaling pathway targeted to promote spinal cord repair.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020801
Title: Effects of cell tension on the small GTPase Rac.
Journal: The Journal of cell biology 20020708
Title: Possible interrelationship between changes in F-actin and myosin II, protein phosphorylation, and cell volume regulation in Ehrlich ascites tumor cells.
Journal: Experimental cell research 20020701
Title: Inhibition of Rho-kinase induces alphaB-crystallin expression in lens epithelial cells.
Journal: Biochemical and biophysical research communications 20020628
Title: Rho family GTP binding proteins are involved in the regulatory volume decrease process in NIH3T3 mouse fibroblasts.
Journal: The Journal of physiology 20020615
Title: Inhibition of Rho/Rho-kinase signaling downregulates plasminogen activator inhibitor-1 synthesis in cultured human monocytes.
Journal: Biochimica et biophysica acta 20020612
Title: Membrane depolarization-induced contraction of rat caudal arterial smooth muscle involves Rho-associated kinase.
Journal: The Biochemical journal 20020601
Title: Vasospasm following subarachnoid hemorrhage: evidence against functional upregulation of Rho kinase constrictor pathway.
Journal: Neurological research 20020601
Title: Phosphatidylinositol 4-phosphate 5-kinase is essential for ROCK-mediated neurite remodeling.
Journal: The Journal of biological chemistry 20020510
Title: Inhibition of protein geranylgeranylation and RhoA/RhoA kinase pathway induces apoptosis in human endothelial cells.
Journal: The Journal of biological chemistry 20020503
Title: Involvement of Rho-kinase pathway for angiotensin II-induced plasminogen activator inhibitor-1 gene expression and cardiovascular remodeling in hypertensive rats.
Journal: The Journal of pharmacology and experimental therapeutics 20020501
Title: Increased activity of calcium channels and Rho-associated kinase in the basilar artery during chronic hypertension in vivo.
Journal: Journal of hypertension 20020501
Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
Journal: The Journal of biological chemistry 20020419
Title: Cooperativity between the Ras-ERK and Rho-Rho kinase pathways in urokinase-type plasminogen activator-stimulated cell migration.
Journal: The Journal of biological chemistry 20020405
Title: Effects of Y-27632, a Rho/Rho kinase inhibitor, on leukotriene D(4)- and histamine-induced airflow obstruction and airway microvascular leakage in guinea pigs in vivo.
Journal: Pharmacology 20020401
Title: Regulation of capacitative and noncapacitative receptor-operated Ca2+ entry by rho-kinase in tracheal smooth muscle.
Journal: American journal of respiratory cell and molecular biology 20020401
Title: Inhibition of rho-kinase-induced myristoylated alanine-rich C kinase substrate (MARCKS) phosphorylation in human neuronal cells by H-1152, a novel and specific Rho-kinase inhibitor.
Journal: Journal of neurochemistry 20020401
Title: Protein kinases--the major drug targets of the twenty-first century?
Journal: Nature reviews. Drug discovery 20020401
Title: Nitric oxide inhibits RhoA/Rho-kinase signaling to cause penile erection.
Journal: European journal of pharmacology 20020329
Title: Rho/ROCK pathway contributes to the activation of extracellular signal-regulated kinase/GATA-4 during myocardial cell hypertrophy.
Journal: The Journal of biological chemistry 20020308
Title: Long-term effects of benidipine on cerebral vasoreactivity in hypertensive rats.
Journal: European journal of pharmacology 20020308
Title: RhoA/Rho kinase and nitric oxide modulate the agonist-induced pulmonary artery diameter response time.
Journal: American journal of physiology. Heart and circulatory physiology 20020301
Title: The protein kinase A inhibitor H89 acts on cell morphology by inhibiting Rho kinase.
Journal: The Journal of pharmacology and experimental therapeutics 20020301
Title: Rho-kinase as a novel therapeutic target in treatment of cardiovascular diseases.
Journal: Journal of cardiovascular pharmacology 20020301
Title: Role of Rho-associated protein kinase and histamine in lysophosphatidic acid-induced airway hyperresponsiveness in guinea pigs.
Journal: Japanese journal of pharmacology 20020301
Title: Cardiac effects of a selective rho-associated kinase inhibitor, Y-27632, assessed in canine isolated, blood-perfused heart preparations.
Journal: Japanese journal of pharmacology 20020301
Title: HMG-CoA reductase inhibitors reduce interleukin-6 synthesis in human vascular smooth muscle cells.
Journal: Cardiovascular drugs and therapy 20020301
Title: HMG-CoA reductase inhibitors suppress intracellular calcium mobilization and membrane current induced by lysophosphatidylcholine in endothelial cells.
Journal: Circulation 20020226
Title: Molecular mechanism for endothelin-1-induced stress-fiber formation: analysis of G proteins using a mutant endothelin(A) receptor.
Journal: Molecular pharmacology 20020201
Title: Expression and modulation of Rho kinase in human pregnant myometrium.
Journal: Molecular human reproduction 20020201
Title: Important role of Rho-kinase in the pathogenesis of cardiovascular inflammation and remodeling induced by long-term blockade of nitric oxide synthesis in rats.
Journal: Hypertension (Dallas, Tex. : 1979) 20020201
Title: Nitric oxide induces dilation of rat aorta via inhibition of rho-kinase signaling.
Journal: Hypertension (Dallas, Tex. : 1979) 20020201
Title: Circumferential stretching of saphenous vein smooth muscle enhances vasoconstrictor responses by Rho kinase-dependent pathways.
Journal: Cardiovascular research 20020101
Title: A role for the Rho-p160 Rho coiled-coil kinase axis in the chemokine stromal cell-derived factor-1alpha-induced lymphocyte actomyosin and microtubular organization and chemotaxis.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20020101
Title: Thromboxane receptor signalling in human myometrial cells.
Journal: Prostaglandins & other lipid mediators 20020101
Title: Microtubule-dependent regulation of vasomotor tone requires Rho-kinase.
Journal: Journal of vascular research 20020101
Title: Rac, a small guanosine triphosphate-binding protein, and p21-activated kinase are activated during platelet spreading on collagen-coated surfaces: roles of integrin alpha(2)beta(1).
Journal: Blood 20011215
Title: Modulation of COX-2 expression by statins in human aortic smooth muscle cells. Involvement of geranylgeranylated proteins.
Journal: The Journal of biological chemistry 20011214
Title: Activation of phospholipase D in porcine tracheal smooth muscle: role of phosphatidylinositol 3-kinase and RhoA activation.
Journal: European journal of pharmacology 20011214
Title: Rho inhibits cAMP-induced translocation of aquaporin-2 into the apical membrane of renal cells.
Journal: American journal of physiology. Renal physiology 20011201
Title: Sphingosine 1-phosphate contracts canine basilar arteries in vitro and in vivo: possible role in pathogenesis of cerebral vasospasm.
Journal: Stroke 20011201
Title: Decreased penile erection in DOCA-salt and stroke prone-spontaneously hypertensive rats.
Journal: International journal of impotence research 20011201
Title: A role for a RhoA/ROCK/LIM-kinase pathway in the regulation of cytotoxic lymphocytes.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20011115
Title: Rho-kinase regulates myosin II activation in MDCK cells during recovery after ATP depletion.
Journal: American journal of physiology. Renal physiology 20011101
Title: The functional role of rho and rho-associated coiled-coil forming protein kinase in eotaxin signaling of eosinophils.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20011015
Title: Inhibitory effect of Y-27632, a ROCK inhibitor, on progression of rat liver fibrosis in association with inactivation of hepatic stellate cells.
Journal: Journal of hepatology 20011001
Title: Thrombin-induced activation of RhoA in platelet shape change.
Journal: Biochemical and biophysical research communications 20010914
Title: Effects of Y-27632 on acetylcholine-induced contraction of intact and permeabilized intrapulmonary bronchial smooth muscles in rats.
Journal: European journal of pharmacology 20010907
Title: Effect of Rho-kinase inhibition on vasoconstriction in the penile circulation.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20010901
Title: Dependency of detrusor contractions on calcium sensitization and calcium entry through LOE-908-sensitive channels.
Journal: British journal of pharmacology 20010901
Title: Role of Rho-associated protein kinase in tone and calcium sensitivity of cannulated rat mesenteric small arteries.
Journal: Experimental physiology 20010901
Title: Role of lysophosphatidylcholine in the desensitization of beta-adrenergic receptors by Ca(2+) sensitization in tracheal smooth muscle.
Journal: American journal of respiratory cell and molecular biology 20010901
Title: Histamine-induced vasoconstriction involves phosphorylation of a specific inhibitor protein for myosin phosphatase by protein kinase C alpha and delta isoforms.
Journal: The Journal of biological chemistry 20010803
Title: Alpha1-adrenoceptor-Gq-RhoA signaling is upregulated to increase myofibrillar Ca2+ sensitivity in failing hearts.
Journal: American journal of physiology. Heart and circulatory physiology 20010801
Title: Oxytocin and lysophosphatidic acid induce stress fiber formation in human myometrial cells via a pathway involving Rho-kinase.
Journal: Biology of reproduction 20010801
Title: Involvement of Rho-kinase and the actin filament network in angiotensin II-induced contraction and extracellular signal-regulated kinase activity in intact rat mesenteric resistance arteries.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20010801
Title: Inhibition of neurite extension by overexpression of individual domains of LIM kinase 1.
Journal: Journal of neurochemistry 20010801
Title: Involvement of a calcium-independent pathway in plasmin-induced platelet shape change.
Journal: Life sciences 20010713
Title: Regulation by GDI of RhoA/Rho-kinase-induced Ca2+ sensitization of smooth muscle myosin II.
Journal: American journal of physiology. Cell physiology 20010701
Title: Augmented acetylcholine-induced translocation of RhoA in bronchial smooth muscle from antigen-induced airway hyperresponsive rats.
Journal: British journal of pharmacology 20010701
Title: Distinct pathways of Ca(2+) sensitization in porcine coronary artery: effects of Rho-related kinase and protein kinase C inhibition on force and intracellular Ca(2+).
Journal: Circulation research 20010622
Title: Thiophosphorylation-induced Ca(2+) sensitization of guinea-pig ileum contractility is not mediated by Rho-associated kinase.
Journal: The Journal of physiology 20010615
Title: Y-27632, an inhibitor of Rho-associated kinases, prevents tyrosine phosphorylation of focal adhesion kinase and paxillin induced by bombesin: dissociation from tyrosine phosphorylation of p130(CAS).
Journal: Experimental cell research 20010610
Title: Human urotensin II-induced contraction and arterial smooth muscle cell proliferation are mediated by RhoA and Rho-kinase.
Journal: Circulation research 20010608
Title: Possible involvement of Rho kinase in Ca2+ sensitization and mobilization by MCh in tracheal smooth muscle.
Journal: American journal of physiology. Lung cellular and molecular physiology 20010601
Title: Y-27632, an inhibitor of Rho-kinase, antagonizes noradrenergic contractions in the rabbit and human penile corpus cavernosum.
Journal: British journal of pharmacology 20010601
Title: Reduction of intraocular pressure by topical administration of an inhibitor of the Rho-associated protein kinase.
Journal: Current eye research 20010601
Title: Involvement of Rho-kinase and tyrosine kinase in hypotonic stress-induced ATP release in bovine aortic endothelial cells.
Journal: The Journal of physiology 20010501
Title: Evidence that Rho-kinase activity contributes to cerebral vascular tone in vivo and is enhanced during chronic hypertension: comparison with protein kinase C.
Journal: Circulation research 20010427
Title: Rho-Rho kinase is involved in smooth muscle cell migration through myosin light chain phosphorylation-dependent and independent pathways.
Journal: Atherosclerosis 20010401
Title: Rho and Rac but not Cdc42 regulate endothelial cell permeability.
Journal: Journal of cell science 20010401
Title: Modulation of aqueous humor outflow facility by the Rho kinase-specific inhibitor Y-27632.
Journal: Investigative ophthalmology & visual science 20010401
Title: Small GTP-binding protein, Rho, both increased and decreased cellular motility, activation of matrix metalloproteinase 2 and invasion of human osteosarcoma cells.
Journal: Japanese journal of cancer research : Gann 20010401
Title: A selective ROCK inhibitor, Y27632, prevents dimethylnitrosamine-induced hepatic fibrosis in rats.
Journal: Journal of hepatology 20010401
Title: Myotonic dystrophy protein kinase phosphorylates the myosin phosphatase targeting subunit and inhibits myosin phosphatase activity.
Journal: FEBS letters 20010330
Title: Inhibition of intrahepatic metastasis of human hepatocellular carcinoma by Rho-associated protein kinase inhibitor Y-27632.
Journal: Hepatology (Baltimore, Md.) 20010301
Title: Alternatives to Viagra.
Journal: Trends in molecular medicine 20010301
Title: Rho-kinase is involved in the sustained phosphorylation of myosin and the irreversible platelet aggregation induced by PAR1 activating peptide.
Journal: Thrombosis and haemostasis 20010301
Title: RhoA/rho-associated kinase mediates fibroblast contractile force generation.
Journal: Biochemical and biophysical research communications 20010209
Title: Small GTPase Rho regulates thrombin-induced platelet aggregation.
Journal: Biochemical and biophysical research communications 20010202
Title: Enhancement of Rho/Rho-kinase system in regulation of vascular smooth muscle contraction in tachycardia-induced heart failure.
Journal: Cardiovascular research 20010201
Title: Arachidonic acid-induced Ca2+ sensitization of smooth muscle contraction through activation of Rho-kinase.
Journal: Pflugers Archiv : European journal of physiology 20010201
Title: Specific activation of LIM kinase 2 via phosphorylation of threonine 505 by ROCK, a Rho-dependent protein kinase.
Journal: The Journal of biological chemistry 20010105
Title: Smooth muscle differentiation marker gene expression is regulated by RhoA-mediated actin polymerization.
Journal: The Journal of biological chemistry 20010105
Title: Effects of rho-associated protein kinase inhibitor Y-27632 on intraocular pressure and outflow facility.
Journal: Investigative ophthalmology & visual science 20010101
Title: Leukotriene C(4) enhances the contraction of porcine tracheal smooth muscle through the activation of Y-27632, a rho kinase inhibitor, sensitive pathway.
Journal: British journal of pharmacology 20010101
Title: Microtubule disruption modulates the Rho-kinase pathway in vascular smooth muscle.
Journal: Journal of muscle research and cell motility 20010101
Title: Importance of Rho-kinase-mediated phosphorylation of myosin light chain in vasospasm.
Journal: Acta neurochirurgica. Supplement 20010101
Title: Enhanced relaxation to the rho-kinase inhibitor Y-27632 in mesenteric arteries from mineralocorticoid hypertensive rats.
Journal: Pharmacology 20010101
Title: Specificity and mechanism of action of some commonly used protein kinase inhibitors.
Journal: The Biochemical journal 20001001
Title: Y-27632 potentiates relaxant effects of beta 2-adrenoceptor agonists in bovine tracheal smooth muscle.
Journal: European journal of pharmacology 20000211
Title: Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension.
Journal: Nature 19971030
Title: Androgens induce nongenomic stimulation of colonic contractile activity through induction of calcium sensitization and phosphorylation of LC20 and CPI-17.
Journal: Molecular endocrinology (Baltimore, Md.)
Title: Ishizaki T, et al. Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases. Mol Pharmacol. 2000 May;57(5):976-83.
Title: Xue ZW, et al. Rho-associated coiled kinase inhibitor Y-27632 promotes neuronal-like differentiation of adult human adipose tissue-derived stem cells.Chin Med J (Engl). 2012 Sep;125(18):3332-5.
Title: Tada S, et al. A selective ROCK inhibitor, Y27632, prevents dimethylnitrosamine-induced hepatic fibrosis in rats. J Hepatol. 2001 Apr;34(4):529-36.
Title: Inan S, et al. Antiepileptic effects of two Rho-kinase inhibitors, Y-27632 and fasudil, in mice. Br J Pharmacol. 2008 Sep;155(1):44-51.
Title: Maldonado M, et al. ROCK inhibitor primes human induced pluripotent stem cells to selectively differentiate towardsmesendodermal lineage via epithelial-mesenchymal transition-like modulation. Stem Cell Res. 2016 Sep;17(2):222-227.
Title: Kan L, et al. Rho-Associated Kinase Inhibitor (Y-27632) Attenuates Doxorubicin-Induced Apoptosis of Human Cardiac Stem Cells. PLoS One. 2015;10(12):e0144513. Published 2015 Dec 8.
Title: Zhang L, et al. ROCK inhibitor Y-27632 suppresses dissociation-induced apoptosis of murine prostate stem/progenitor cells and increases their cloning efficiency. PLoS One. 2011;6(3):e18271. Published 2011 Mar 28.
Title: Svoboda KK, et al. ROCK inhibitor (Y27632) increases apoptosis and disrupts the actin cortical mat in embryonic avian corneal epithelium. Dev Dyn. 2004;229(3):579-590.
