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148-53-8,MFCD00003322
Catalog No.:AA00339J

148-53-8 | 2-Hydroxy-3-methoxybenzaldehyde

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Technical Information
Catalog Number:
AA00339J
Chemical Name:
2-Hydroxy-3-methoxybenzaldehyde
CAS Number:
148-53-8
Molecular Formula:
C8H8O3
Molecular Weight:
152.1473
MDL Number:
MFCD00003322
SMILES:
COc1cccc(c1O)C=O
NSC Number:
2150
Properties
Properties
 
BP:
265.5°C at 760 mmHg  
Form:
Solid  
MP:
40-42 °C(lit.)  
Refractive Index:
1.4945 (estimate)  
Stability:
Air Sensitive  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
135  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
1.4  

Literature

Title: 2-Hy-droxy-3-meth-oxy-benzaldehyde (o-vanillin) revisited.

Journal: Acta crystallographica. Section E, Structure reports online 20120801

Title: The conductance of red blood cells from sickle cell patients: ion selectivity and inhibitors.

Journal: The Journal of physiology 20120501

Title: catena-Poly[copper(II)-bis-(μ-2-formyl-6-meth-oxy-phenolato-κO,O:O,O)-[(methanol-κO)sodium]-μ-perchlorato-κO:O'].

Journal: Acta crystallographica. Section E, Structure reports online 20120201

Title: Food protective effects of Periploca sepium oil and its active component against stored food mites.

Journal: Journal of food protection 20120101

Title: catena-Poly[[bis-(μ-2-formyl-6-meth-oxy-phenolato-1:2κO,O:O,O)copper(II)sodium]-μ-tetra-fluorido-borate-1:1'κF:F'].

Journal: Acta crystallographica. Section E, Structure reports online 20120101

Title: Spectrophotometric Determination of Iron(II) and Cobalt(II) by Direct, Derivative, and Simultaneous Methods Using 2-Hydroxy-1-Naphthaldehyde-p-Hydroxybenzoichydrazone.

Journal: International journal of analytical chemistry 20120101

Title: (E)-5-[(2-Hy-droxy-3-meth-oxy-benzyl-idene)amino]-1,3,4-thia-diazole-2(3H)-thione.

Journal: Acta crystallographica. Section E, Structure reports online 20111201

Title: Syntheses, spectral, electrochemical and thermal studies of mononuclear manganese(III) complexes with ligands derived from 1,2-propanediamine and 2-hydroxy-3 or 5-methoxybenzaldehyde: self-assembled monolayer formation on nanostructure zinc oxide thin film.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110801

Title: Magnetic exchange interactions and magneto-structural correlations in heterobridged μ-phenoxo-μ(1,1)-azide dinickel(II) compounds: a combined experimental and theoretical exploration.

Journal: Inorganic chemistry 20110801

Title: 2-Cyano-N'-(2-hy-droxy-3-meth-oxy-benzyl-idene)acetohydrazide.

Journal: Acta crystallographica. Section E, Structure reports online 20110801

Title: 14-Methoxy-2,16-dioxapentacyclo[7.7.5.0.0.0]henicosa-3(8),10,12,14-tetraene-7,20-dione.

Journal: Acta crystallographica. Section E, Structure reports online 20110801

Title: A new Mo Schiff base complex: methanol[N'-(3-meth-oxy-2-oxidobenzyl-idene)benzohydrazidato]dioxido-molybdenum(VI).

Journal: Acta crystallographica. Section E, Structure reports online 20110701

Title: Syntheses, structures, and magnetic properties of three one-dimensional end-to-end azide/cyanate-bridged copper(II) compounds exhibiting ferromagnetic interaction: new type of solid state isomerism.

Journal: Inorganic chemistry 20110620

Title: New cyanide-bridged Mn(III)-M(III) heterometallic dinuclear complexes constructed from [M(III)(AA)(CN)4]- building blocks (M = Cr and Fe): synthesis, crystal structures and magnetic properties.

Journal: Dalton transactions (Cambridge, England : 2003) 20110514

Title: Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonuclease.

Journal: The Journal of biological chemistry 20110408

Title: Spectroscopic analyses on interaction of o-Vanillin-D-Phenylalanine, o-Vanillin-L-Tyrosine and o-Vanillin-L-Levodopa Schiff Bases with bovine serum albumin (BSA).

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110401

Title: Structures and magnetism of {Ni2Na2}, {Ni4} and {Ni6(II)Ni(III)} 2-hydroxy-3-alkoxy-benzaldehyde clusters.

Journal: Dalton transactions (Cambridge, England : 2003) 20110328

Title: [N'-(3-Meth-oxy-2-oxidobenzyl-idene-κO)benzohydrazidato-κN',O]tris-(pyridine-κN)cobalt(III) perchlorate.

Journal: Acta crystallographica. Section E, Structure reports online 20110301

Title: Bis(2-{[2-(isopropyl-aza-nium-yl)eth-yl]imino-meth-yl}-6-meth-oxy-phenolato)copper(II) bis-(thio-cyanate).

Journal: Acta crystallographica. Section E, Structure reports online 20110201

Title: 1,2-Bis(2-meth-oxy-6-formyl-phen-oxy)ethane.

Journal: Acta crystallographica. Section E, Structure reports online 20110201

Title: Bis{(E)-2-[(2-chloro-3-pyrid-yl)imino-meth-yl]-6-meth-oxy-phenolato-κN,O}copper(II).

Journal: Acta crystallographica. Section E, Structure reports online 20110101

Title: Antifungal activity of redox-active benzaldehydes that target cellular antioxidation.

Journal: Annals of clinical microbiology and antimicrobials 20110101

Title: Tetra-μ(3)-methano-lato-tetra-kis-[(2-formyl-6-meth-oxy-phenolato)methano-lnickel(II)].

Journal: Acta crystallographica. Section E, Structure reports online 20101101

Title: 2-Hydroxy-3-methoxybenzaldehyde 2,4-dinitrophenylhydrazone pyridine monosolvate.

Journal: Acta crystallographica. Section E, Structure reports online 20100901

Title: Bis{2-[(2-benzoyl-hydrazin-1-yl-idene)meth-yl]-6-meth-oxy-phenolato}iron(III) chloride monohydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20100701

Title: Bis[μ-2-(2-benzoyl-hydrazinylidenemeth-yl)-6-methoxy-phenolato][2-(2-benzoyl-hydrazinylidenemeth-yl)-6-methoxy-phenolato]dimanganese(II) perchlorate methanol solvate.

Journal: Acta crystallographica. Section E, Structure reports online 20100601

Title: Hexaaqua-manganese(II) bis-{[N-(3-meth-oxy-2-oxidobenzyl-idene)glycylglycinato]copper(II)} hexa-hydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20100501

Title: (E)-2-[1-(3-Amino-4-chloro-phenyl-imino)eth-yl]-4-bromo-phenol.

Journal: Acta crystallographica. Section E, Structure reports online 20100401

Title: 6-Acetoxy-methyl-3-[(2-hydr-oxy-3-methoxy-benzyl-idene)amino]-3,4,5,6-tetra-hydro-2H-pyran-2,4,5-triyl triacetate.

Journal: Acta crystallographica. Section E, Structure reports online 20100401

Title: 6,6'-Dimeth-oxy-2,2'-[4,5-dimethyl-o-phenyl-enebis(nitrilo-methyl-idyne)]diphenol monohydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20100301

Title: (E)-2-[(2-Ethyl-phen-yl)imino-meth-yl]-6-methoxy-phenol.

Journal: Acta crystallographica. Section E, Structure reports online 20100201

Title: Synthesis and characterisation of thiosemicarbazonato molybdenum(VI) complexes and their in vitro antitumor activity.

Journal: European journal of medicinal chemistry 20100101

Title: Bis[2-meth-oxy-6-(3-pyridylmethyl-imino-meth-yl)phenolato-κN,O]copper(II).

Journal: Acta crystallographica. Section E, Structure reports online 20100101

Title: 6,6'-Dimeth-oxy-2,2'-[pyridine-2,3-diylbis(nitrilo-methyl-idyne)]diphenol.

Journal: Acta crystallographica. Section E, Structure reports online 20100101

Title: Aqua-{6,6-dimeth-oxy-2,2'-[propane-1,3-diylbis(nitrilo-methyl-idyne)]diphenolato-κO,N,N',O'}copper(II) acetonitrile solvate.

Journal: Acta crystallographica. Section E, Structure reports online 20091201

Title: (E)-2-Meth-oxy-6-(thia-zol-2-ylimino-meth-yl)phenol.

Journal: Acta crystallographica. Section E, Structure reports online 20091101

Title: (E)-2-{4-[1-(Hydroxyimino)ethyl]phenyl-iminomethyl}-6-methoxyphenol mono-hydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20091101

Title: Aqua-{6,6'-dimeth-oxy-2,2'-[ethane-1,2-diylbis(nitrilo-methyl-idyne)]diphenolato}nickel(II).

Journal: Acta crystallographica. Section E, Structure reports online 20091001

Title: {6,6'-Dimeth-oxy-2,2'-[ethane-1,2-diylbis(nitrilo-methyl-idyne)]diphenolato-1κO,O,O,O:2κO,N,N',O}(ethanol-1κO)-μ-nitrato-1:2κO:O'-dinitrato-1κO,O'-samarium(III)zinc(II).

Journal: Acta crystallographica. Section E, Structure reports online 20091001

Title: 6,6'-Dimeth-oxy-2,2'-[(E,E')-(4-chloro-m-phenyl-ene)bis-(nitrilo-methyl-idyne)]diphenol.

Journal: Acta crystallographica. Section E, Structure reports online 20091001

Title: A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta.

Journal: Bioorganic & medicinal chemistry letters 20090901

Title: Aqua-{6,6'-dimeth-oxy-2,2'-[ethane-1,2-diylbis(nitrilo-methyl-idyne)]diphenolato}(4-hydroxy-benzoato)manganese(III).

Journal: Acta crystallographica. Section E, Structure reports online 20090901

Title: 2-Meth-oxy-6-(6-methyl-1H-benzimid-azol-2-yl)phenol.

Journal: Acta crystallographica. Section E, Structure reports online 20090701

Title: 2-Meth-oxy-6-(6-methyl-1H-benzimidazol-2-yl)phenol.

Journal: Acta crystallographica. Section E, Structure reports online 20090601

Title: (E,E)-6,6'-Dimeth-oxy-2,2'-[o-phenyl-ene-bis(nitrilo-methyl-idyne)]diphenol.

Journal: Acta crystallographica. Section E, Structure reports online 20090401

Title: (E)-2-[(6-Ethoxy-benzothia-zol-2-yl)imino-meth-yl]-6-methoxy-phenol.

Journal: Acta crystallographica. Section E, Structure reports online 20090401

Title: {6,6'-Dimeth-oxy-2,2'-[6-bromo-pyridine-2,3-diylbis(nitrilo-methyl-idyne)]-diphenol-ato}-copper(II) methanol solvate.

Journal: Acta crystallographica. Section E, Structure reports online 20090301

Title: 2-[6,8-Dibromo-3-(4-hydroxy-cyclo-hexyl)-1,2,3,4-tetra-hydro-quinazolin-2-yl]-6-methoxy-phenol.

Journal: Acta crystallographica. Section E, Structure reports online 20090301

Title: (E)-2-[(2-Hydroxy-ethyl)iminiometh-yl]-6-methoxy-phenolate.

Journal: Acta crystallographica. Section E, Structure reports online 20090301

Title: (E)-2-[(2-Amino-4,5-dibromo-phen-yl)imino-meth-yl]-6-methoxy-phenol.

Journal: Acta crystallographica. Section E, Structure reports online 20090201

Title: (2,2'-Bipyridine)(2-formyl-6-methoxy-phenolato)nickel(II) perchlorate.

Journal: Acta crystallographica. Section E, Structure reports online 20090101

Title: 6,6'-Dimeth-oxy-2,2'-[2,2-dimethyl-propane-1,3-diylbis(nitrilo-methyl-idyne)]diphenol.

Journal: Acta crystallographica. Section E, Structure reports online 20090101

Title: N'-(2-Hydr-oxy-3-methoxy-benzyl-idene)-1,3-benzodioxole-5-carbohydrazide monohydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20090101

Title: Spectrometric study of tautomeric and protonation equilibria of o-vanillin Schiff base derivatives and their complexes with Cu(II).

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081215

Title: Bis(2-hydroxy-imino-methyl-6-methoxy-phenolato-κO,N)cobalt(II).

Journal: Acta crystallographica. Section E, Structure reports online 20081201

Title: 4-Hydr-oxy-N'-(2-hydr-oxy-3-methoxy-benzyl-idene)benzohydrazide mono-hydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20081001

Title: A 2D coordination polymer with canted ferromagnetism constructed from ferromagnetic [Ni(II)Co(II)] nodes.

Journal: Inorganic chemistry 20080804

Title: Di-μ-oxido-bis-{[(R,R)-(+)-1-amino-2-(3-methoxy-2-oxidobenzyl-ideneamino-κO,N)-1,2-diphenyl-ethane-κN]oxidovanadium(V)} dihydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20080701

Title: {μ-6,6'-Dimeth-oxy-2,2'-[ethane-1,2-diylbis(nitrilo-methyl-idyne)]diphenolato}-μ-nitrato-dinitratoholmium(III)zinc(II).

Journal: Acta crystallographica. Section E, Structure reports online 20080601

Title: 1,2-Bis[(2-hydr-oxy-3-methoxy-benzyl-idene)hydrazono]-1,2-diphenyl-ethane.

Journal: Acta crystallographica. Section E, Structure reports online 20080601

Title: (E)-2-Hydr-oxy-3-methoxy-benzaldehyde thio-semicarbazone.

Journal: Acta crystallographica. Section E, Structure reports online 20080601

Title: Bis[4-(2-hydr-oxy-3-methoxy-benzyl-ideneamino)phen-yl] ether.

Journal: Acta crystallographica. Section E, Structure reports online 20080601

Title: (Z)-2-(2-Chloro-3,3,3-trifluoro-prop-1-en-yl)-6-methoxy-phenyl acetate.

Journal: Acta crystallographica. Section E, Structure reports online 20080601

Title: Bis{2-meth-oxy-6-[3-(methyl-amino)propyl-imino-meth-yl]phenolato}nickel(II) bis-(perchlorate).

Journal: Acta crystallographica. Section E, Structure reports online 20080501

Title: (2,2'-Bipyridine-κN,N'){[(3-meth-oxy-2-oxidobenzyl-idene-κO)hydrazono]methano-lato-κN,O}dimethyl-tin(IV).

Journal: Acta crystallographica. Section E, Structure reports online 20080401

Title: {μ-6,6'-Dimeth-oxy-2,2'-[ethane-1,2-diylbis(nitrilo-methyl-idyne)]diphenolato}-μ-nitrato-dinitratoterbium(III)zinc(II).

Journal: Acta crystallographica. Section E, Structure reports online 20080401

Title: (E)-2-Meth-oxy-6-[(5-methyl-isoxazol-3-yl)imino-meth-yl]phenol.

Journal: Acta crystallographica. Section E, Structure reports online 20080201

Title: cis-Bis[2-(cyclo-propyl-imino-meth-yl)-6-methoxy-phenolato]bis-(thio-cyanato)cobalt(II).

Journal: Acta crystallographica. Section E, Structure reports online 20080101

Title: {μ-6,6'-Dimeth-oxy-2,2'-[ethane-1,2-diylbis(nitrilo-methyl-idyne)]diphenolato}-μ-nitrato-dinitratoeuropium(III)zinc(II).

Journal: Acta crystallographica. Section E, Structure reports online 20080101

Title: Metal complexes of Schiff base derived from sulphametrole and o-vanilin. Synthesis, spectral, thermal characterization and biological activity.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070401

Title: 3D-QSAR and molecular docking studies of benzaldehyde thiosemicarbazone, benzaldehyde, benzoic acid, and their derivatives as phenoloxidase inhibitors.

Journal: Bioorganic & medicinal chemistry 20070301

Title: Salicylate ion-selective electrode based on new tetranuclear copper complexes of O-vannlin-methionine as neutral carriers.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20070201

Title: Effect of natural phenol derivatives on skeletal type sarcoplasmic reticulum Ca2+ -ATPase and ryanodine receptor.

Journal: Journal of muscle research and cell motility 20070101

Title: Simultaneous Determination of Cobalt(II) and Nickel(II) by Fourth-Order Derivative Spectrophotometric Method Using 2-Hydroxy-3-Methoxy Benzaldehyde Thiosemicarbazone.

Journal: Journal of automated methods & management in chemistry 20070101

Title: Interaction of vanadyl (VO2+) with ligands containing serine, tyrosine, and threonine.

Journal: Inorganic chemistry 20060904

Title: Method for determining the average degree of substitution of o-vanillin derivatized porcine somatotropin.

Journal: Journal of pharmaceutical and biomedical analysis 20060123

Title: Oligonuclear 3d-4f complexes as tectons in designing supramolecular solid-state architectures: impact of the nature of linkers on the structural diversity.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20051216

Title: Gastrointestinally distributed UDP-glucuronosyltransferase 1A10, which metabolizes estrogens and nonsteroidal anti-inflammatory drugs, depends upon phosphorylation.

Journal: The Journal of biological chemistry 20040702

Title: Antibacterial activities of phenolic benzaldehydes and benzoic acids against Campylobacter jejuni, Escherichia coli, Listeria monocytogenes, and Salmonella enterica.

Journal: Journal of food protection 20031001

Title: Synthesis and characterization of a novel cross-linking complex of beta-cyclodextrin-o-vanillin benzoylhydrazone and its selective spectrofluorimetric determination of trace amounts of zinc.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20030901

Title: Vibrational analysis of substituted phenols: part I. Vibrational spectra, normal coordinate analysis and transferability of force constants of some formyl-, methoxy-, formylmethoxy-, methyl- and halogeno-phenols.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20021201

Title: Heterobinuclear complexes as building blocks in designing extended structures.

Journal: Inorganic chemistry 20021021

Title: Syntheses, X-ray crystal structures, and magnetic properties of novel linear M2[II]U[IV] complexes (M=Co, Ni, Cu, Zn).

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20020215

Title: Free radical scavenging activity of vanillin and o-vanillin using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical.

Journal: Redox report : communications in free radical research 20020101

Title: Dissolution behavior of porcine somatotropin with simultaneous gel formation and lysine Schiff-base hydrolysis.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20011109

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Tags:148-53-8 Molecular Formula|148-53-8 MDL|148-53-8 SMILES|148-53-8 2-Hydroxy-3-methoxybenzaldehyde |Organic_Building_Blocks