Home Other Building Blocks 149377-19-5
149377-19-5,MFCD09261337
Catalog No.:AA001LJS

149377-19-5 | 1-Boc-4-p-hydroxyphenylpiperidine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
97%
in stock  
$128.00   $90.00
- +
1g
97%
in stock  
$286.00   $200.00
- +
5g
97%
in stock  
$834.00   $584.00
- +
10g
97%
in stock  
$1,167.00   $817.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA001LJS
Chemical Name:
1-Boc-4-p-hydroxyphenylpiperidine
CAS Number:
149377-19-5
Molecular Formula:
C16H23NO3
Molecular Weight:
277.3587
MDL Number:
MFCD09261337
SMILES:
O=C(N1CCC(CC1)c1ccc(cc1)O)OC(C)(C)C
Properties
Computed Properties
 
Complexity:
321  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
XLogP3:
3  

Downstream Synthesis Route
40032-76-6    149377-19-5   
tert-butyl4-(4-((2-bromothiophen-3-yl)methoxy)phenyl)piperidine-1-carboxylate 

[1]Ehara,Takeru;Adams,ChristopherM.;Bevan,Doug;Ji,Nan;Meredith,ErikL.;Belanger,DavidB.;Powers,James;Kato,Mitsunori;Solovay,Catherine;Liu,Donglei;Capparelli,Michael;Bolduc,Philippe;Grob,JonathanE.;Daniels,MatthewH.;Ferrara,Luciana;Yang,Louis;Li,Byron;Towler,ChristopherS.;Stacy,RebeccaC.;Prasanna,Ganesh;Mogi,Muneto[JournalofMedicinalChemistry,2018,vol.61,#6,p.2552-2570]

[2]CurrentPatentAssignee:Novartis(w/oSandoz);NOVARTISAG-WO2016/1876,2016,A1Locationinpatent:Page/Pagecolumn63

CASUnavailable 
  1869912-48-0    149377-19-5 

[1]CurrentPatentAssignee:ASTRAZENECAPLC-WO2016/16618,2016,A1Locationinpatent:Page/Pagecolumn61

[1]Bradbury,RobertH.;Callis,Rowena;Carr,GregoryR.;Chen,Huawei;Clark,Edwin;Feron,Lyman;Glossop,Steve;Graham,MarkA.;Hattersley,Maureen;Jones,Chris;Lamont,ScottG.;Ouvry,Gilles;Patel,Anil;Patel,Joe;Rabow,AlfredA.;Roberts,CraigA.;Stokes,Stephen;Stratton,Natalie;Walker,GraemeE.;Ward,Lara;Whalley,David;Whittaker,David;Wrigley,Gail;Waring,MichaelJ.[JournalofMedicinalChemistry,2016,vol.59,#17,p.7801-7817]

[2]CurrentPatentAssignee:C4THERAPEUTICSINC;BIOGENIDECINC.-WO2022/235945,2022,A1Locationinpatent:Page/Pagecolumn161

[1]AngewandteChemie-InternationalEdition,2017,vol.56,p.16318-16322    Angew.Chem.,2017,vol.129,p.16536-16540,5

Literature
Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:149377-19-5 Molecular Formula|149377-19-5 MDL|149377-19-5 SMILES|149377-19-5 1-Boc-4-p-hydroxyphenylpiperidine