Title: Heme Oxygenase-1 protects astroglia against manganese-induced oxidative injury by regulating mitochondrial quality control.
Journal: Toxicology letters 20181001
Title: Dihydronortanshinone, a natural product, alleviates LPS-induced inflammatory response through NF-κB, mitochondrial ROS, and MAPK pathways.
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Title: Synergistic action of the nephrotoxic mycotoxins ochratoxin A and citrinin at nanomolar concentrations in human proximal tubule-derived cells.
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Title: ROS generation and MAPKs activation contribute to the Ni-induced testosterone synthesis disturbance in rat Leydig cells.
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Title: t-BuOOH induces ferroptosis in human and murine cell lines.
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Title: The sp(2)-iminosugar glycolipid 1-dodecylsulfonyl-5N,6O-oxomethylidenenojirimycin (DSO(2)-ONJ) as selective anti-inflammatory agent by modulation of hemeoxygenase-1 in Bv.2 microglial cells and retinal explants.
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Title: Arsenite exposure potentiates apoptosis-inducing effects of tumor necrosis factor-alpha- through reactive oxygen species.
Journal: The Journal of toxicological sciences 20180101
Title: Methylmercury promotes prostacyclin release from cultured human brain microvascular endothelial cells via induction of cyclooxygenase-2 through activation of the EGFR-p38 MAPK pathway by inhibiting protein tyrosine phosphatase 1B activity.
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Title: PKA/CREB and NF-κB pathway regulates AKNA transcription: A novel insight into T-2 toxin-induced inflammation and GH deficiency in GH3 cells.
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Title: Polysaccharide purified from Ganoderma atrum induced activation and maturation of murine myeloid-derived dendritic cells.
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Title: Varenicline promotes endothelial cell migration by lowering vascular endothelial-cadherin levels via the activated α7 nicotinic acetylcholine receptor-mitogen activated protein kinase axis.
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Title: Soluble epoxide hydrolase inhibitor AUDA decreases bleomycin-induced pulmonary toxicity in mice by inhibiting the p38/Smad3 pathways.
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Title: Taiwanin E inhibits cell migration in human LoVo colon cancer cells by suppressing MMP-2/9 expression via p38 MAPK pathway.
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Title: Nimbolide induces apoptosis in human nasopharyngeal cancer cells.
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Title: Cannabidiol upregulates melanogenesis through CB1 dependent pathway by activating p38 MAPK and p42/44 MAPK.
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Title: Adiponectin promotes human jaw bone marrow mesenchymal stem cell chemotaxis via CXCL1 and CXCL8.
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Title: Sinigrin attenuates the progression of atherosclerosis in ApoE(-/-) mice fed a high-cholesterol diet potentially by inhibiting VCAM-1 expression.
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Title: Amyloid β induces NLRP3 inflammasome activation in retinal pigment epithelial cells via NADPH oxidase- and mitochondria-dependent ROS production.
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Title: Inhibitory effects of Leucaena leucocephala on the metastasis and invasion of human oral cancer cells.
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Title: The flame retardant 2,2',4,4'-Tetrabromodiphenyl ether enhances the expression of corticotropin-releasing hormone in the placental cell model JEG-3.
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Title: Cadmium-induced IL-6 and IL-8 expression and release from astrocytes are mediated by MAPK and NF-κB pathways.
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Title: Secondhand Smoke-Prevalent Polycyclic Aromatic Hydrocarbon Binary Mixture-Induced Specific Mitogenic and Pro-inflammatory Cell Signaling Events in Lung Epithelial Cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20170501
Title: Dysregulation of MAP Kinase Signaling Pathways Including p38MAPK, SAPK/JNK, and ERK1/2 in Cultured Rat Cerebellar Astrocytes Exposed to Diphenylarsinic Acid.
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Title: Andrographolide inhibits hypoxia-induced HIF-1α-driven endothelin 1 secretion by activating Nrf2/HO-1 and promoting the expression of prolyl hydroxylases 2/3 in human endothelial cells.
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Title: Airborne fine particulate matter causes murine bronchial hyperreactivity via MAPK pathway-mediated M(3) muscarinic receptor upregulation.
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Title: Inhibition of NF-κB and metastasis in irinotecan (CPT-11)-resistant LoVo colon cancer cells by thymoquinone via JNK and p38.
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Title: Insights on wood combustion generated proinflammatory ultrafine particles (UFP).
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Title: mTOR inhibition by rapamycin protects against deltamethrin-induced apoptosis in PC12 Cells.
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Title: Salvianolic Acid A Protects H9c2 Cells from Arsenic Trioxide-Induced Injury via Inhibition of the MAPK Signaling Pathway.
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Title: Semisynthetic flavonoid 7-O-galloylquercetin activates Nrf2 and induces Nrf2-dependent gene expression in RAW264.7 and Hepa1c1c7 cells.
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Title: Aflatoxin B1 disrupts transient receptor potential channel activity and increases COX-2 expression in JEG-3 placental cells.
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Title: Cucurbitacin-I induces hypertrophy in H9c2 cardiomyoblasts through activation of autophagy via MEK/ERK1/2 signaling pathway.
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Title: Gene expression profile induced by arsenic trioxide in chronic lymphocytic leukemia cells reveals a central role for heme oxygenase-1 in apoptosis and regulation of matrix metalloproteinase-9.
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Title: Quercetin inhibits LPS-induced adhesion molecule expression and oxidant production in human aortic endothelial cells by p38-mediated Nrf2 activation and antioxidant enzyme induction.
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Title: Activation of p38 Mitogen-Activated Protein Kinase by Clotrimazole Induces Multidrug Resistance-Associated Protein 3 Activation through a Novel Transcriptional Element.
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Title: Mitogen-activated protein kinase p38 target regenerating islet-derived 3γ expression is upregulated in cardiac inflammatory response in the rat heart.
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Title: Inhibition of interleukin-1β-induced endothelial tissue factor expression by the synthetic cannabinoid WIN 55,212-2.
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Title: Human precision-cut liver slices as a model to test antifibrotic drugs in the early onset of liver fibrosis.
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Title: Hexachlorobenzene modulates the crosstalk between the aryl hydrocarbon receptor and transforming growth factor-β1 signaling, enhancing human breast cancer cell migration and invasion.
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Title: Afzelin positively regulates melanogenesis through the p38 MAPK pathway.
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Title: Carbon monoxide releasing molecule-2 ameliorates IL-1β-induced IL-8 in human gastric cancer cells.
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Title: Involvement of PI3K/Akt, ERK and p38 signaling pathways in emodin-mediated extrinsic and intrinsic human hepatoblastoma cell apoptosis.
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Title: The Identification and Pharmacological Characterization of 6-(tert-Butylsulfonyl)-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine (GSK583), a Highly Potent and Selective Inhibitor of RIP2 Kinase.
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Title: MCPIP1 Regulates Alveolar Macrophage Apoptosis and Pulmonary Fibroblast Activation After in vitro Exposure to Silica.
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Title: TCDD promoted EMT of hFPECs via AhR, which involved the activation of EGFR/ERK signaling.
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Title: Megakaryocytic Maturation in Response to Shear Flow Is Mediated by the Activator Protein 1 (AP-1) Transcription Factor via Mitogen-activated Protein Kinase (MAPK) Mechanotransduction.
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Title: Effects of urban particulate matter with high glucose on human monocytes U937.
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Title: Brominated flame retardants, hexabromocyclododecane and tetrabromobisphenol A, affect proinflammatory protein expression in human bronchial epithelial cells via disruption of intracellular signaling.
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Title: Decreased hepatic phosphorylated p38 mitogen-activated protein kinase contributes to attenuation of thioacetamide-induced hepatic necrosis in diet-induced obese mice.
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Title: Bakuchiol augments MyoD activation leading to enhanced myoblast differentiation.
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Title: Hydroquinone stimulates cell invasion through activator protein-1-dependent induction of MMP-9 in HepG2 human hepatoma cells.
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Title: MAPK and SHH pathways modulate type 3 deiodinase expression in papillary thyroid carcinoma.
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Title: Cigarette smoke extract-induced interleukin-6 expression is regulated by phospholipase D1 in human bronchial epithelial cells.
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Title: Transforming growth factor-β1 acts via TβR-I on microglia to protect against MPP(+)-induced dopaminergic neuronal loss.
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Title: The Role of MAPK Pathways in Airborne Fine Particulate Matter-Induced Upregulation of Endothelin Receptors in Rat Basilar Arteries.
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Title: Ghrelin protects against depleted uranium-induced apoptosis of MC3T3-E1 cells through oxidative stress-mediated p38-mitogen-activated protein kinase pathway.
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Title: The role of HO-1 in protection against lead-induced neurotoxicity.
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Title: DJ-1 mutation decreases astroglial release of inflammatory mediators.
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Title: Osmotic Induction of Angiogenic Growth Factor Expression in Human Retinal Pigment Epithelial Cells.
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Title: Diesel Exhaust Particles Upregulate Interleukins IL-6 and IL-8 in Nasal Fibroblasts.
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Title: Diesel Exhaust Particles Enhance MUC4 Expression in NCI-H292 Cells and Nasal Epithelial Cells via the p38/CREB Pathway.
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Title: Induction of HO-1 by carbon monoxide releasing molecule-2 attenuates thrombin-induced COX-2 expression and hypertrophy in primary human cardiomyocytes.
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Title: Apoptosis induced by temozolomide and nimustine in glioblastoma cells is supported by JNK/c-Jun-mediated induction of the BH3-only protein BIM.
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Title: Role of human pulmonary fibroblast-derived MCP-1 in cell activation and migration in experimental silicosis.
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Title: Oroxin B selectively induces tumor-suppressive ER stress and concurrently inhibits tumor-adaptive ER stress in B-lymphoma cells for effective anti-lymphoma therapy.
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Title: Integrated Transcriptional and Proteomic Analysis of Growth Hormone Suppression Mediated by Trichothecene T-2 Toxin in Rat GH3 Cells.
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Title: Novel Nrf2/ARE activator, trans-Coniferylaldehyde, induces a HO-1-mediated defense mechanism through a dual p38α/MAPKAPK-2 and PK-N3 signaling pathway.
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Title: Quercetin protects mouse liver against CCl₄-induced inflammation by the TLR2/4 and MAPK/NF-κB pathway.
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Title: Aspidin PB, a novel natural anti-fibrotic compound, inhibited fibrogenesis in TGF-β1-stimulated keloid fibroblasts via PI-3K/Akt and Smad signaling pathways.
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Title: The involvement of p62-Keap1-Nrf2 antioxidative signaling pathway and JNK in the protection of natural flavonoid quercetin against hepatotoxicity.
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Title: Resveratrol Enhances Chemosensitivity in Mouse Melanoma Model Through Connexin 43 Upregulation.
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Title: Hyperphosphorylation of microfilament-associated proteins is involved in microcystin-LR-induced toxicity in HL7702 cells.
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Title: Tetramethylpyrazine (TMP) protects against sodium arsenite-induced nephrotoxicity by suppressing ROS production, mitochondrial dysfunction, pro-inflammatory signaling pathways and programed cell death.
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Title: Gambogic acid sensitizes resistant breast cancer cells to doxorubicin through inhibiting P-glycoprotein and suppressing survivin expression.
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Title: The Food-Associated Ribotoxin Deoxynivalenol Modulates Inducible NO Synthase in Human Intestinal Cell Model.
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Title: Quercetin promotes the osteogenic differentiation of rat mesenchymal stem cells via mitogen-activated protein kinase signaling.
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Title: Cyclosporin A upregulates ETB receptor in vascular smooth muscle via activation of mitogen-activating protein kinases and NF-κB pathways.
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Title: A Role for p38 Mitogen-activated Protein Kinase-mediated Threonine 30-dependent Norepinephrine Transporter Regulation in Cocaine Sensitization and Conditioned Place Preference.
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Title: Transcriptional upregulation centra of HO-1 by EGB via the MAPKs/Nrf2 pathway in mouse C2C12 myoblasts.
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Title: MAPK pathway activation by chronic lead-exposure increases vascular reactivity through oxidative stress/cyclooxygenase-2-dependent pathways.
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Title: Oxidative stress-induced inhibition of Sirt1 by caveolin-1 promotes p53-dependent premature senescence and stimulates the secretion of interleukin 6 (IL-6).
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Title: Trans-resveratrol attenuates high fatty acid-induced P2X7 receptor expression and IL-6 release in PC12 cells: possible role of P38 MAPK pathway.
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Title: Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical for resveratrol-mediated suppression of matrix metalloproteinase-2 and subsequent metastatic ability in human osteosarcomas.
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Title: Acrylamide Induces Senescence in Macrophages through a Process Involving ATF3, ROS, p38/JNK, and a Telomerase-Independent Pathway.
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Title: Carnosic acid protects against 6-hydroxydopamine-induced neurotoxicity in in vivo and in vitro model of Parkinson's disease: involvement of antioxidative enzymes induction.
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Title: Alterations of tau and VASP during microcystin-LR-induced cytoskeletal reorganization in a human liver cell line.
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Title: Resveratrol reduces prostaglandin E1-stimulated osteoprotegerin synthesis in osteoblasts: suppression of stress-activated protein kinase/c-Jun N-terminal kinase.
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Title: Quinoline compound KM11073 enhances BMP-2-dependent osteogenic differentiation of C2C12 cells via activation of p38 signaling and exhibits in vivo bone forming activity.
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Title: Optimized mixture of As, Cd and Pb induce mitochondria-mediated apoptosis in C6-glioma via astroglial activation, inflammation and P38-MAPK.
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Title: TSC-22 up-regulates collagen 3a1 gene expression in the rat heart.
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Title: Chronic exposure to asbestos enhances TGF-β1 production in the human adult T cell leukemia virus-immortalized T cell line MT-2.
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Title: Resveratrol post-transcriptionally regulates pro-inflammatory gene expression via regulation of KSRP RNA binding activity.
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Title: Induction of glutathione synthesis in human hepatocytes by acute and chronic arsenic exposure: differential roles of mitogen-activated protein kinases.
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Title: Regulation by resveratrol of prostaglandin E2-stimulated osteoprotegerin synthesis in osteoblasts.
Journal: International journal of molecular medicine 20141101
Title: Induction of GADD45α protects M17 neuroblastoma cells against MPP*.
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Title: Down-regulation by resveratrol of basic fibroblast growth factor-stimulated osteoprotegerin synthesis through suppression of Akt in osteoblasts.
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Title: ERK oscillation-dependent gene expression patterns and deregulation by stress response.
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Title: Apoptosis induced by para-phenylenediamine involves formation of ROS and activation of p38 and JNK in chang liver cells.
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Title: Suppression by resveratrol of prostaglandin D2-stimulated osteoprotegerin synthesis in osteoblasts.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20140901
Title: Quercetin-3-O-glucuronide inhibits noradrenaline-promoted invasion of MDA-MB-231 human breast cancer cells by blocking β₂-adrenergic signaling.
Journal: Archives of biochemistry and biophysics 20140901
Title: BNIP3 upregulation by ERK and JNK mediates cadmium-induced necrosis in neuronal cells.
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Title: Resveratrol attenuates matrix metalloproteinase-9 and -2-regulated differentiation of HTB94 chondrosarcoma cells through the p38 kinase and JNK pathways.
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Title: Molecular mechanisms of cadmium-induced fibroblast growth factor 23 upregulation in osteoblast-like cells.
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Title: Withaferin A is an inhibitor of endothelial protein C receptor shedding in vitro and in vivo.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20140601
Title: Quercetin induces apoptosis by inhibiting MAPKs and TRPM7 channels in AGS cells.
Journal: International journal of molecular medicine 20140601
Title: Trovafloxacin potentiation of lipopolysaccharide-induced tumor necrosis factor release from RAW 264.7 cells requires extracellular signal-regulated kinase and c-Jun N-Terminal Kinase.
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Title: Downregulation of Rad51 participates in OTA-induced DNA double-strand breaks in GES-1 cells in vitro.
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Title: Quercetin regulates the sestrin 2-AMPK-p38 MAPK signaling pathway and induces apoptosis by increasing the generation of intracellular ROS in a p53-independent manner.
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Title: Silibinin induces apoptosis of HT29 colon carcinoma cells through early growth response-1 (EGR-1)-mediated non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) up-regulation.
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Title: Morphological effects on expression of growth differentiation factor 15 (GDF15), a marker of metastasis.
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Title: Synergistic induction of human cathelicidin antimicrobial peptide gene expression by vitamin D and stilbenoids.
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Title: Penta- and octa-bromodiphenyl ethers promote proinflammatory protein expression in human bronchial epithelial cells in vitro.
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Title: Development of cardiac hypertrophy by sunitinib in vivo and in vitro rat cardiomyocytes is influenced by the aryl hydrocarbon receptor signaling pathway.
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Title: Long term intake of 0.1% ethanol decreases serum adiponectin by suppressing PPARγ expression via p38 MAPK pathway.
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Title: Modulation of keratinocyte expression of antioxidants by 4-hydroxynonenal, a lipid peroxidation end product.
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Title: Regulation of keratinocyte expression of stress proteins and antioxidants by the electrophilic nitrofatty acids 9- and 10-nitrooleic acid.
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Title: Resveratrol suppresses prostaglandin F(2α)-induced osteoprotegerin synthesis in osteoblasts: inhibition of the MAP kinase signaling.
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Title: Lipid peroxidation end product 4-hydroxy-trans-2-nonenal triggers unfolded protein response and heme oxygenase-1 expression in PC12 cells: Roles of ROS and MAPK pathways.
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Title: Evaluation and mechanistic analysis of the cytotoxicity of the acyl glucuronide of nonsteroidal anti-inflammatory drugs.
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Title: The induction of heme oxygenase-1 suppresses heat shock protein 90 and the proliferation of human breast cancer cells through its byproduct carbon monoxide.
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Title: Mitochondrial p38β and manganese superoxide dismutase interaction mediated by estrogen in cardiomyocytes.
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Title: Activation of MAPK and FoxO by manganese (Mn) in rat neonatal primary astrocyte cultures.
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Title: FSL-1 induces MMP-9 production through TLR-2 and NF-κB /AP-1 signaling pathways in monocytic THP-1 cells.
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Title: Δ-Tetrahydrocannabinol induces cytotoxicity in macrophage J774-1 cells: involvement of cannabinoid receptor 2 and p38 MAPK.
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Title: Involvement of the p38 MAPK signaling pathway in S-phase cell-cycle arrest induced by Furazolidone in human hepatoma G2 cells.
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Title: Comparison of wood smoke PM2.5 obtained from the combustion of FIR and beech pellets on inflammation and DNA damage in A549 and THP-1 human cell lines.
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Title: Phosphorylation of FOXO3a by PI3K/Akt pathway in HK-2 renal proximal tubular epithelial cells exposed to cadmium.
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Title: Quercetin disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-κB-induced inflammatory mediators production in RAW 264.7 cells.
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Title: Induction of steroid sulfatase expression in PC-3 human prostate cancer cells by insulin-like growth factor II.
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Title: Ethanol increases matrix metalloproteinase-12 expression via NADPH oxidase-dependent ROS production in macrophages.
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Title: Carbon monoxide alleviates ethanol-induced oxidative damage and inflammatory stress through activating p38 MAPK pathway.
Journal: Toxicology and applied pharmacology 20131115
Title: ONTD induces apoptosis of human hepatoma Bel-7402 cells via a MAPK-dependent mitochondrial pathway and the depletion of intracellular glutathione.
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Title: Saikosaponin D disrupts platelet-derived growth factor-β receptor/p38 pathway leading to mitochondrial apoptosis in human LO2 hepatocyte cells: a potential mechanism of hepatotoxicity.
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Title: The generation of 4-hydroxynonenal, an electrophilic lipid peroxidation end product, in rabbit cornea organ cultures treated with UVB light and nitrogen mustard.
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Title: μ opioid receptor agonist-selective regulation of interleukin-4 in T lymphocytes.
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Title: Arsenic induces the expressions of angiogenesis-related factors through PI3K and MAPK pathways in SV-HUC-1 human uroepithelial cells.
Journal: Toxicology letters 20131009
Title: Fenofibrate suppresses melanogenesis in B16-F10 melanoma cells via activation of the p38 mitogen-activated protein kinase pathway.
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Title: Cytokine regulation by MAPK activated kinase 2 in keratinocytes exposed to sulfur mustard.
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Title: Proteomic analysis identifies an NADPH oxidase 1 (Nox1)-mediated role for actin-related protein 2/3 complex subunit 2 (ARPC2) in promoting smooth muscle cell migration.
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Title: Small molecule sensitization to TRAIL is mediated via nuclear localization, phosphorylation and inhibition of chaperone activity of Hsp27.
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Title: Sertoli cell is a potential target for perfluorooctane sulfonate-induced reproductive dysfunction in male mice.
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Title: Immunostimulatory activity of polysaccharides from Cheonggukjang.
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Title: Tributyltin induces oxidative damage, inflammation and apoptosis via disturbance in blood-brain barrier and metal homeostasis in cerebral cortex of rat brain: an in vivo and in vitro study.
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Title: Mechanisms of ceramide-induced COX-2-dependent apoptosis in human ovarian cancer OVCAR-3 cells partially overlapped with resveratrol.
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Title: Curcumin inhibits oxLDL-induced CD36 expression and foam cell formation through the inhibition of p38 MAPK phosphorylation.
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Title: Fumaric acid attenuates the eotaxin-1 expression in TNF-α-stimulated fibroblasts by suppressing p38 MAPK-dependent NF-κB signaling.
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Title: Suppression of iNOS and COX-2 expression by flavokawain A via blockade of NF-κB and AP-1 activation in RAW 264.7 macrophages.
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Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.
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Title: Inhibitory effect of resveratrol dimerized derivatives on nitric oxide production in lipopolysaccharide-induced RAW 264.7 cells.
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Title: Brazilein suppresses migration and invasion of MDA-MB-231 breast cancer cells.
Journal: Chemico-biological interactions 20130705
Title: Role of hypoxia-inducible factor 1, α subunit and cAMP-response element binding protein 1 in synergistic release of interleukin 8 by prostaglandin E2 and nickel in lung fibroblasts.
Journal: American journal of respiratory cell and molecular biology 20130701
Title: Galangin attenuates mast cell-mediated allergic inflammation.
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Title: Inhibition of ROS-activated p38MAPK pathway is involved in the protective effect of H2S against chemical hypoxia-induced inflammation in PC12 cells.
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Title: Oxidative stress and MAPK involved into ATF2 expression in immortalized human urothelial cells treated by arsenic.
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Title: Low molecular weight chitosan accelerates glucagon-like peptide-1 secretion in human intestinal endocrine cells via a p38-dependent pathway.
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Title: Interaction of inflammatory and anti-inflammatory responses in microglia by Staphylococcus aureus-derived lipoteichoic acid.
Journal: Toxicology and applied pharmacology 20130515
Title: JNK and p38 MAPK regulate oxidative stress and the inflammatory response in chlorpyrifos-induced apoptosis.
Journal: Toxicology letters 20130426
Title: A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
Journal: The Biochemical journal 20130415
Title: Mercury induces proliferation and reduces cell size in vascular smooth muscle cells through MAPK, oxidative stress and cyclooxygenase-2 pathways.
Journal: Toxicology and applied pharmacology 20130415
Title: Titanium dioxide nanoparticles increase inflammatory responses in vascular endothelial cells.
Journal: Toxicology 20130405
Title: Sodium arsenite induces cyclooxygenase-2 expression in human uroepithelial cells through MAPK pathway activation and reactive oxygen species induction.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20130401
Title: β-Ionone attenuates LPS-induced pro-inflammatory mediators such as NO, PGE2 and TNF-α in BV2 microglial cells via suppression of the NF-κB and MAPK pathway.
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Title: Attenuated expression of the tight junction proteins is involved in clopidogrel-induced gastric injury through p38 MAPK activation.
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Title: p38 MAP kinase and ERK play an important role in nitric oxide-induced apoptosis of the mouse embryonic stem cells.
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Title: Resveratrol induces MMP-9 and cell migration via the p38 kinase and PI-3K pathways in HT1080 human fibrosarcoma cells.
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Title: Chloroacetic acid induced neuronal cells death through oxidative stress-mediated p38-MAPK activation pathway regulated mitochondria-dependent apoptotic signals.
Journal: Toxicology 20130107
Title: Role of 15-hydroxyeicosatetraenoic acid in hemozoin-induced lysozyme release from human adherent monocytes.
Journal: BioFactors (Oxford, England) 20130101
Title: The MAPK pathway signals telomerase modulation in response to isothiocyanate-induced DNA damage of human liver cancer cells.
Journal: PloS one 20130101
Title: A critical role for MAPK signalling pathways in the transcriptional regulation of toll like receptors.
Journal: PloS one 20130101
Title: Inhibitory effects of resveratrol on PDGF-BB-induced retinal pigment epithelial cell migration via PDGFRβ, PI3K/Akt and MAPK pathways.
Journal: PloS one 20130101
Title: Oxidative stress and mitogen-activated protein kinase pathways involved in cadmium-induced BRL 3A cell apoptosis.
Journal: Oxidative medicine and cellular longevity 20130101
Title: p38/AP-1 pathway in lipopolysaccharide-induced inflammatory responses is negatively modulated by electrical stimulation.
Journal: Mediators of inflammation 20130101
Title: Antioxidant and anti-inflammatory effects in RAW264.7 macrophages of malvidin, a major red wine polyphenol.
Journal: PloS one 20130101
Title: Induction of miR-21-PDCD4 signaling by tungsten carbide-cobalt nanoparticles in JB6 cells involves ROS-mediated MAPK pathways.
Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20130101
Title: GATA-2 transduces LPS-induced il-1β gene expression in macrophages via a toll-like receptor 4/MD88/MAPK-dependent mechanism.
Journal: PloS one 20130101
Title: Environmental alkylphenols modulate cytokine expression in plasmacytoid dendritic cells.
Journal: PloS one 20130101
Title: Ouabain, a cardiac glycoside, inhibits the Fanconi anemia/BRCA pathway activated by DNA interstrand cross-linking agents.
Journal: PloS one 20130101
Title: ROS detoxification and proinflammatory cytokines are linked by p38 MAPK signaling in a model of mature astrocyte activation.
Journal: PloS one 20130101
Title: High glucose-induced increased expression of endothelin-1 in human endothelial cells is mediated by activated CCAAT/enhancer-binding proteins.
Journal: PloS one 20130101
Title: Altered MAPK signaling in progressive deterioration of endothelial function in diabetic mice.
Journal: Diabetes 20121201
Title: L-ascorbate attenuates methamphetamine neurotoxicity through enhancing the induction of endogenous heme oxygenase-1.
Journal: Toxicology and applied pharmacology 20121201
Title: Significant correlation between the acceleration of platelet aggregation and phosphorylation of HSP27 at Ser-78 in diabetic patients.
Journal: International journal of molecular medicine 20121201
Title: Melittin suppresses VEGF-A-induced tumor growth by blocking VEGFR-2 and the COX-2-mediated MAPK signaling pathway.
Journal: Journal of natural products 20121126
Title: Aspartic acid substitutions in monoamine oxidase-A reveal both catalytic-dependent and -independent influences on cell viability and proliferation.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20121101
Title: Apoptosis signal-regulating kinase 1 is mediated in TNF-α-induced CCL2 expression in human synovial fibroblasts.
Journal: Journal of cellular biochemistry 20121101
Title: Melamine induces human renal proximal tubular cell injury via transforming growth factor-β and oxidative stress.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20121101
Title: Hyperphosphorylation of intermediate filament proteins is involved in microcystin-LR-induced toxicity in HL7702 cells.
Journal: Toxicology letters 20121017
Title: Temperature-related effects of adenosine triphosphate-activated microglia on pro-inflammatory factors.
Journal: Neurocritical care 20121001
Title: Heat shock protein 27 expression in areca quid chewing-associated oral squamous cell carcinomas.
Journal: Oral diseases 20121001
Title: Protective role of quercetin against lead-induced inflammatory response in rat kidney through the ROS-mediated MAPKs and NF-κB pathway.
Journal: Biochimica et biophysica acta 20121001
Title: Transcriptional and translational regulation of COX-2 expression by cadmium in C6 glioma cells.
Journal: International journal of molecular medicine 20121001
Title: Targeting the hinge glycine flip and the activation loop: novel approach to potent p38α inhibitors.
Journal: Journal of medicinal chemistry 20120913
Title: Naringin attenuates EGF-induced MUC5AC secretion in A549 cells by suppressing the cooperative activities of MAPKs-AP-1 and IKKs-IκB-NF-κB signaling pathways.
Journal: European journal of pharmacology 20120905
Title: The organochlorine o,p'-DDT plays a role in coactivator-mediated MAPK crosstalk in MCF-7 breast cancer cells.
Journal: Environmental health perspectives 20120901
Title: NF-κΒ inhibition is ineffective in blocking cytokine-induced IL-8 production but P38 and STAT1 inhibitors are effective.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20120901
Title: Activation of macrophages by polysaccharide isolated from Paecilomyces cicadae through toll-like receptor 4.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120901
Title: Quercetin enhances ABCA1 expression and cholesterol efflux through a p38-dependent pathway in macrophages.
Journal: Journal of lipid research 20120901
Title: Sargachromanol G regulates the expression of osteoclastogenic factors in human osteoblast-like MG-63 cells.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120901
Title: The p38 MAPK-MK2 axis regulates E2F1 and FOXM1 expression after epirubicin treatment.
Journal: Molecular cancer research : MCR 20120901
Title: Increased type 3 deiodinase expression in papillary thyroid carcinoma.
Journal: Thyroid : official journal of the American Thyroid Association 20120901
Title: Pimaric acid from Aralia cordata has an inhibitory effect on TNF-α-induced MMP-9 production and HASMC migration via down-regulated NF-κB and AP-1.
Journal: Chemico-biological interactions 20120830
Title: Suppression of adhesion molecule expression by phenanthrene-containing extract of bulbils of Chinese Yam in vascular smooth muscle cells through inhibition of MAPK, Akt and NF-κB.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120801
Title: Synthesis and biological evaluation of 4-alkoxy-6,9-dichloro[1,2,4]triazolo[4,3-a]quinoxalines as inhibitors of TNF-α and IL-6.
Journal: European journal of medicinal chemistry 20120801
Title: Roles of 7-ketocholesterol on the homeostasis of intracellular cholesterol level.
Journal: Journal of cardiovascular pharmacology 20120801
Title: Involvement of diacylglycerol kinase γ in modulation of iNOS synthesis in Golgi apparatus of vascular endothelial cells.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20120801
Title: Design and synthesis of novel p38α MAP kinase inhibitors: discovery of pyrazole-benzyl ureas bearing 2-molpholinopyrimidine moiety.
Journal: Bioorganic & medicinal chemistry letters 20120801
Title: Sphingosine-1-phosphate modulates expression of vascular endothelial growth factor in human articular chondrocytes: a possible new role in arthritis.
Journal: International journal of rheumatic diseases 20120801
Title: Prodigiosin-induced cytotoxicity involves RAD51 down-regulation through the JNK and p38 MAPK pathways in human breast carcinoma cell lines.
Journal: Toxicology letters 20120707
Title: Allicin inhibits cell growth and induces apoptosis in U87MG human glioblastoma cells through an ERK-dependent pathway.
Journal: Oncology reports 20120701
Title: p38 inhibitor SB203580 sensitizes the resveratrol-induced apoptosis in human lung adenocarcinoma (A549) cells.
Journal: Journal of biochemical and molecular toxicology 20120701
Title: Design, synthesis, and biological evaluation of novel disubstituted dibenzosuberones as highly potent and selective inhibitors of p38 mitogen activated protein kinase.
Journal: Journal of medicinal chemistry 20120628
Title: Single molecule analysis of serotonin transporter regulation using antagonist-conjugated quantum dots reveals restricted, p38 MAPK-dependent mobilization underlying uptake activation.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120627
Title: Ethanol transiently suppresses choline-acetyltransferase in basal nucleus of Meynert slices.
Journal: Brain research 20120612
Title: ICAM-1 and IL-8 are expressed by DEHP and suppressed by curcumin through ERK and p38 MAPK in human umbilical vein endothelial cells.
Journal: Inflammation 20120601
Title: Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) mediates p38 mitogen-activated protein kinase activation and signal transduction in peripheral blood mononuclear cells from patients with lupus nephritis.
Journal: Inflammation 20120601
Title: Sevoflurane inhibits invasion and migration of lung cancer cells by inactivating the p38 MAPK signaling pathway.
Journal: Journal of anesthesia 20120601
Title: Arsenic modulates heme oxygenase-1, interleukin-6, and vascular endothelial growth factor expression in endothelial cells: roles of ROS, NF-κB, and MAPK pathways.
Journal: Archives of toxicology 20120601
Title: Tumor necrosis factor-α and interleukin-1β expression pathway induced by Streptococcus mutans in macrophage cell line RAW 264.7.
Journal: Molecular oral microbiology 20120601
Title: Toll/interleukin-1 receptor domain-containing adapter inducing interferon-β mediates microglial phagocytosis of degenerating axons.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120530
Title: Resveratrol downregulates acute pulmonary thromboembolism-induced pulmonary artery hypertension via p38 mitogen-activated protein kinase and monocyte chemoattractant protein-1 signaling in rats.
Journal: Life sciences 20120522
Title: Intermittent hypoxia conditioning protects mitochondrial cytochrome c oxidase of rat cerebellum from ethanol withdrawal stress.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20120515
Title: The pro-apoptotic effect of quercetin in cancer cell lines requires ERβ-dependent signals.
Journal: Journal of cellular physiology 20120501
Title: Molecular mechanisms of early growth response protein-1 (EGR-1) expression by quercetin in INS-1 beta-cells.
Journal: Journal of cellular biochemistry 20120501
Title: Inhibition of p38 pathway leads to OA-like changes in a rat animal model.
Journal: Rheumatology (Oxford, England) 20120501
Title: Nocodazole increases the ERK activity to enhance MKP-1expression which inhibits p38 activation induced by TNF-α.
Journal: Molecular and cellular biochemistry 20120501
Title: 1-Bromopropane up-regulates cyclooxygenase-2 expression via NF-κB and C/EBP activation in murine macrophages.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120501
Title: S1P2 receptor mediates sphingosine-1-phosphate-induced fibronectin expression via MAPK signaling pathway in mesangial cells under high glucose condition.
Journal: Experimental cell research 20120501
Title: Bidirectional regulation of neutrophil migration by mitogen-activated protein kinases.
Journal: Nature immunology 20120501
Title: Effects of cobalt chloride on nitric oxide and cytokines/chemokines production in microglia.
Journal: International immunopharmacology 20120501
Title: ETS-1 protein regulates vascular endothelial growth factor-induced matrix metalloproteinase-9 and matrix metalloproteinase-13 expression in human ovarian carcinoma cell line SKOV-3.
Journal: The Journal of biological chemistry 20120427
Title: Negative regulation of human U6 snRNA promoter by p38 kinase through Oct-1.
Journal: Gene 20120415
Title: Rottlerin induces apoptosis of HT29 colon carcinoma cells through NAG-1 upregulation via an ERK and p38 MAPK-dependent and PKC δ-independent mechanism.
Journal: Chemico-biological interactions 20120415
Title: p38 mitogen-activated protein kinase (MAPK) promotes cholesterol ester accumulation in macrophages through inhibition of macroautophagy.
Journal: The Journal of biological chemistry 20120406
Title: Enhanced phosphorylation of MAPKs by NE promotes TNF-α production by macrophage through α adrenergic receptor.
Journal: Inflammation 20120401
Title: IL-33 is induced by amyloid-β stimulation and regulates inflammatory cytokine production in retinal pigment epithelium cells.
Journal: Inflammation 20120401
Title: Ethanol extract of Prunella vulgaris var. lilacina inhibits HMGB1 release by induction of heme oxygenase-1 in LPS-activated RAW 264.7 cells and CLP-induced septic mice.
Journal: Phytotherapy research : PTR 20120401
Title: Melamine causes apoptosis of rat kidney epithelial cell line (NRK-52e cells) via excessive intracellular ROS (reactive oxygen species) and the activation of p38 MAPK pathway.
Journal: Cell biology international 20120401
Title: Apoptotic signaling in endothelial cells with neutrophil activation.
Journal: Molecular and cellular biochemistry 20120401
Title: MKP-1: a negative feedback effector that represses MAPK-mediated pro-inflammatory signaling pathways and cytokine secretion in human airway smooth muscle cells.
Journal: Cellular signalling 20120401
Title: Dynamics and regulation of lipid droplet formation in lipopolysaccharide (LPS)-stimulated microglia.
Journal: Biochimica et biophysica acta 20120401
Title: Interaction between head and neck squamous cell carcinoma cells and fibroblasts in the biosynthesis of PGE2.
Journal: Journal of lipid research 20120401
Title: ERK and p38 MAPK signaling pathways are involved in ochratoxin A-induced G2 phase arrest in human gastric epithelium cells.
Journal: Toxicology letters 20120307
Title: Inhibitory effects of enalaprilat on rat cardiac fibroblast proliferation via ROS/P38MAPK/TGF-β1 signaling pathway.
Journal: Molecules (Basel, Switzerland) 20120306
Title: p38 MAPK regulates calcium signal-mediated lipid accumulation through changing VDR expression in primary preadipocytes of mice.
Journal: Molecular biology reports 20120301
Title: The p38 mitogen-activated protein kinases modulate endothelial cell survival and tissue repair.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20120301
Title: Combination effects of cigarette smoke extract and ambient ultrafine particles on endothelial cells.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20120301
Title: Lantana macrophylla Schauer (Verbenaceae) ethanolic extract induces activation of ERK1/2 and p38 MAPKs pathway and Ca2+ imbalance in human trophoblasts derived cell lines.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120301
Title: Uncoordinated regulation of atrial natriuretic factor and brain natriuretic peptide in lipopolysaccharide-treated rats.
Journal: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20120301
Title: GEF-H1/RhoA signalling pathway mediates lipopolysaccharide-induced intercellular adhesion molecular-1 expression in endothelial cells via activation of p38 and NF-κB.
Journal: Cytokine 20120301
Title: Regulation of HGF-mediated cell proliferation and invasion through NF-κB, JunB, and MMP-9 cascades in stomach cancer cells.
Journal: Clinical & experimental metastasis 20120301
Title: Nicotine stimulates urokinase-type plasminogen activator receptor expression and cell invasiveness through mitogen-activated protein kinase and reactive oxygen species signaling in ECV304 endothelial cells.
Journal: Toxicology and applied pharmacology 20120301
Title: Fructose-1,6-bisphosphate attenuates induction of nitric oxide synthase in microglia stimulated with lipopolysaccharide.
Journal: Life sciences 20120227
Title: An essential role for modulation of hyperpolarization-activated current in the development of binaural temporal precision.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120222
Title: MAPK- and PKC/CREB-dependent induction of interleukin-11 by the environmental contaminant formaldehyde in human bronchial epithelial cells.
Journal: Toxicology 20120206
Title: Calcium ameliorates obesity induced by high-fat diet and its potential correlation with p38 MAPK pathway.
Journal: Molecular biology reports 20120201
Title: Lipopolysaccharide upregulates the expression of corticotropin-releasing hormone via MAP kinase pathway in rat peritoneal macrophages.
Journal: Molecular and cellular biochemistry 20120201
Title: Isoeugenol destabilizes IL-8 mRNA expression in THP-1 cells through induction of the negative regulator of mRNA stability tristetraprolin.
Journal: Archives of toxicology 20120201
Title: Activation of p38 signaling in the microglia in the nucleus accumbens contributes to the acquisition and maintenance of morphine-induced conditioned place preference.
Journal: Brain, behavior, and immunity 20120201
Title: The role of MAPK and Nrf2 pathways in ketanserin-elicited attenuation of cigarette smoke-induced IL-8 production in human bronchial epithelial cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120201
Title: Heme oxygenase-1 mediates the protective role of quercetin against ethanol-induced rat hepatocytes oxidative damage.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20120201
Title: An NF-κB-independent and Erk1/2-dependent mechanism controls CXCL8/IL-8 responses of airway epithelial cells to cadmium.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120201
Title: Regulation of peroxisome proliferator-activated receptor-γ by angiotensin II via transforming growth factor-β1-activated p38 mitogen-activated protein kinase in aortic smooth muscle cells.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20120201
Title: Gene pathway analysis of the mechanism by which the Rho-associated kinase inhibitor Y-27632 inhibits apoptosis in isolated thawed human embryonic stem cells.
Journal: Cryobiology 20120201
Title: Quercetin modulates Nrf2 and glutathione-related defenses in HepG2 cells: Involvement of p38.
Journal: Chemico-biological interactions 20120125
Title: Inhibition of signal transducer and activator of transcription 3 (STAT3) attenuates interleukin-6 (IL-6)-induced collagen synthesis and resultant hypertrophy in rat heart.
Journal: The Journal of biological chemistry 20120120
Title: Prostaglandin E2 enhances interleukin-8 production via EP4 receptor in human pulmonary microvascular endothelial cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20120115
Title: A pharmacologically-based array to identify targets of cyclosporine A-induced toxicity in cultured renal proximal tubule cells.
Journal: Toxicology and applied pharmacology 20120115
Title: Bone morphogenetic protein (BMP)-4 and BMP-7 suppress granulosa cell apoptosis via different pathways: BMP-4 via PI3K/PDK-1/Akt and BMP-7 via PI3K/PDK-1/PKC.
Journal: Biochemical and biophysical research communications 20120113
Title: Blockade of microglial activation reduces mechanical allodynia in rats with compression of the trigeminal ganglion.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20120110
Title: p38 mitogen-activated protein kinase is a key regulator of 5-phenylselenyl- and 5-methylselenyl-methyl-2'-deoxyuridine-induced apoptosis in human HL-60 cells.
Journal: Biochemical and biophysical research communications 20120106
Title: Prunus yedoensis Matsum. stimulates glucose uptake in L6 rat skeletal muscle cells by activating AMP-activated protein kinase and phosphatidylinositol 3-kinase/Akt pathways.
Journal: Natural product research 20120101
Title: p38 MAPK activation, JNK inhibition, neoplastic growth inhibition, and increased gap junction communication in human lung carcinoma and Ras-transformed cells by 4-phenyl-3-butenoic acid.
Journal: Journal of cellular biochemistry 20120101
Title: Mechanisms involved in enhancement of the expression and function of aggrecanases by hyaluronan oligosaccharides.
Journal: Arthritis and rheumatism 20120101
Title: Interaction between ROS and p38MAPK contributes to chemical hypoxia-induced injuries in PC12 cells.
Journal: Molecular medicine reports 20120101
Title: Sulfur mustard primes human neutrophils for increased degranulation and stimulates cytokine release via TRPM2/p38 MAPK signaling.
Journal: Toxicology and applied pharmacology 20120101
Title: Role of the Nrf2-heme oxygenase-1 pathway in silver nanoparticle-mediated cytotoxicity.
Journal: Toxicology and applied pharmacology 20120101
Title: Insulin inhibits hepatocyte iNOS expression induced by cytokines by an Akt-dependent mechanism.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20120101
Title: Mutual regulation of growth hormone and bone morphogenetic protein system in steroidogenesis by rat granulosa cells.
Journal: Endocrinology 20120101
Title: 17-Hydroxy-jolkinolide B, a diterpenoid from Euphorbia fischeriana, inhibits inflammatory mediators but activates heme oxygenase-1 expression in lipopolysaccharide-stimulated murine macrophages.
Journal: International immunopharmacology 20120101
Title: miR-16 targets transcriptional corepressor SMRT and modulates NF-kappaB-regulated transactivation of interleukin-8 gene.
Journal: PloS one 20120101
Title: Activation of JNK signaling mediates connective tissue growth factor expression and scar formation in corneal wound healing.
Journal: PloS one 20120101
Title: Hemokinin-1 gene expression is upregulated in microglia activated by lipopolysaccharide through NF-κB and p38 MAPK signaling pathways.
Journal: PloS one 20120101
Title: Hypoxia-induced up-regulation of aquaporin-1 protein in prostate cancer cells in a p38-dependent manner.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Title: Cockroach allergen Per a 7 down-regulates expression of Toll-like receptor 9 and IL-12 release from P815 cells through PI3K and MAPK signaling pathways.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Title: Curcumin protects retinal pigment epithelial cells against oxidative stress via induction of heme oxygenase-1 expression and reduction of reactive oxygen.
Journal: Molecular vision 20120101
Title: Participation of microglial p38 MAPK in formalin-induced temporomandibular joint nociception in rats.
Journal: Journal of orofacial pain 20120101
Title: 17-β-estradiol inhibits hyperosmolarity-induced proinflammatory cytokine elevation via the p38 MAPK pathway in human corneal epithelial cells.
Journal: Molecular vision 20120101
Title: Endothelin-1 stimulates small artery VCAM-1 expression through p38MAPK-dependent neutral sphingomyelinase.
Journal: Journal of vascular research 20120101
Title: Camel milk triggers apoptotic signaling pathways in human hepatoma HepG2 and breast cancer MCF7 cell lines through transcriptional mechanism.
Journal: Journal of biomedicine & biotechnology 20120101
Title: Regulation of interleukin-1alpha and tumor necrosis factor-alpha-induced interleukin-8 production by amnion-derived (WISH) cells.
Journal: Clinical and experimental obstetrics & gynecology 20120101
Title: Marked differences in the signaling requirements for expression of CD203c and CD11b versus CD63 expression and histamine release in human basophils.
Journal: International archives of allergy and immunology 20120101
Title: MCP-1 induced protein promotes adipogenesis via oxidative stress, endoplasmic reticulum stress and autophagy.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Title: MAPK and JAK-STAT signaling pathways are involved in the oxidative stress-induced decrease in expression of surfactant protein genes.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Title: Sunitinib-sensitive suicidal erythrocyte death.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Title: Interleukin-1 induction of aggrecanase gene expression in human articular chondrocytes is mediated by mitogen-activated protein kinases.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Title: Apoptotic effects of satratoxin H is mediated through DNA double-stranded break in PC12 cells.
Journal: The Journal of toxicological sciences 20120101
Title: p38 mitogen-activated protein kinase-induced nuclear factor kappa-light-chain-enhancer of activated B cell activity is required for neuroprotection in retinal ischemia/reperfusion injury.
Journal: Molecular vision 20120101
Title: Inhibition of p38 mitogen-activated protein kinase phosphorylation decrease tert-butyl hydroperoxide-induced apoptosis in human trabecular meshwork cells.
Journal: Molecular vision 20120101
Title: Restoration of corticosteroid sensitivity by p38 mitogen activated protein kinase inhibition in peripheral blood mononuclear cells from severe asthma.
Journal: PloS one 20120101
Title: The apoptotic volume decrease is an upstream event of MAP kinase activation during Staurosporine-induced apoptosis in HeLa cells.
Journal: International journal of molecular sciences 20120101
Title: Protective effect of tropisetron on rodent hepatic injury after trauma-hemorrhagic shock through P38 MAPK-dependent hemeoxygenase-1 expression.
Journal: PloS one 20120101
Title: Angiotensin II protects primary rat hepatocytes against bile salt-induced apoptosis.
Journal: PloS one 20120101
Title: Xanthohumol induces apoptosis in human malignant glioblastoma cells by increasing reactive oxygen species and activating MAPK pathways.
Journal: Journal of natural products 20111227
Title: Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor.
Journal: Nature chemical biology 20111225
Title: Microcystin-LR induces cytoskeleton system reorganization through hyperphosphorylation of tau and HSP27 via PP2A inhibition and subsequent activation of the p38 MAPK signaling pathway in neuroendocrine (PC12) cells.
Journal: Toxicology 20111218
Title: Interplay between vascular endothelial growth factor (VEGF) and nuclear factor erythroid 2-related factor-2 (Nrf2): implications for preeclampsia.
Journal: The Journal of biological chemistry 20111216
Title: Chemical constituents of the rhizomes of Hedychium coronarium and their inhibitory effect on the pro-inflammatory cytokines production LPS-stimulated in bone marrow-derived dendritic cells.
Journal: Bioorganic & medicinal chemistry letters 20111215
Title: Resveratrol, but not dihydroresveratrol, induces premature senescence in primary human fibroblasts.
Journal: Age (Dordrecht, Netherlands) 20111201
Title: Maohuoside A promotes osteogenesis of rat mesenchymal stem cells via BMP and MAPK signaling pathways.
Journal: Molecular and cellular biochemistry 20111201
Title: cPLA(2)α gene activation by IL-1β is dependent on an upstream kinase pathway, enzymatic activation and downstream 15-lipoxygenase activity: a positive feedback loop.
Journal: Cellular signalling 20111201
Title: Differential involvement of ezrin/radixin/moesin proteins in sphingosine 1-phosphate-induced human pulmonary endothelial cell barrier enhancement.
Journal: Cellular signalling 20111201
Title: Apelin-13 passes through the ADMA-damaged endothelial barrier and acts on vascular smooth muscle cells.
Journal: Peptides 20111201
Title: PDGFR-α inhibition preserves blood-brain barrier after intracerebral hemorrhage.
Journal: Annals of neurology 20111201
Title: [Protective effect of remifentanil preconditioning against hepatic ischemia-reperfusion injury in rats: role of p38 mitogen-activated protein kinases].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20111201
Title: 1,7-Naphthyridine 1-oxides as novel potent and selective inhibitors of p38 mitogen activated protein kinase.
Journal: Journal of medicinal chemistry 20111124
Title: Antimetastatic effect and mechanism of ovatodiolide in MDA-MB-231 human breast cancer cells.
Journal: Chemico-biological interactions 20111115
Title: Tumour necrosis factor-α stimulates human neutrophils to release preformed activin A.
Journal: Immunology and cell biology 20111101
Title: Ascorbic acid increases the activity and synthesis of tyrosinase in B16F10 cells through activation of p38 mitogen-activated protein kinase.
Journal: Archives of dermatological research 20111101
Title: High calcium, ATP, and poly(I:C) augment the immune response to β-glucan in normal human epidermal keratinocytes.
Journal: The Journal of investigative dermatology 20111101
Title: Protein phosphatase 2A promotes endothelial survival via stabilization of translational inhibitor 4E-BP1 following exposure to tumor necrosis factor-α.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20111101
Title: Sodium dl-α-tocopheryl-6-O-phosphate inhibits PGE₂ production in keratinocytes induced by UVB, IL-1β and peroxidants.
Journal: Bioorganic & medicinal chemistry 20111101
Title: The Ebolavirus VP24 protein blocks phosphorylation of p38 mitogen-activated protein kinase.
Journal: The Journal of infectious diseases 20111101
Title: Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.
Journal: Nature biotechnology 20111101
Title: [Involvement of p38-p53 signal pathway in resveratrol-induced apoptosis in MCF-7 cells].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20111101
Title: Comprehensive analysis of kinase inhibitor selectivity.
Journal: Nature biotechnology 20111030
Title: The aromatic volatile organic compounds toluene, benzene and styrene induce COX-2 and prostaglandins in human lung epithelial cells via oxidative stress and p38 MAPK activation.
Journal: Toxicology 20111028
Title: Vitamin A (retinol) up-regulates the receptor for advanced glycation endproducts (RAGE) through p38 and Akt oxidant-dependent activation.
Journal: Toxicology 20111028
Title: Design, synthesis, and biological evaluation of chromone-based p38 MAP kinase inhibitors.
Journal: Journal of medicinal chemistry 20111027
Title: Role of VPO1, a newly identified heme-containing peroxidase, in ox-LDL induced endothelial cell apoptosis.
Journal: Free radical biology & medicine 20111015
Title: The Discovery of VX-745: A Novel and Selective p38α Kinase Inhibitor.
Journal: ACS medicinal chemistry letters 20111013
Title: Effects of florfenicol on LPS-induced nitric oxide and prostaglandin E₂ production in RAW 264.7 macrophages.
Journal: Fundamental & clinical pharmacology 20111001
Title: p38 MAPK activation is required for esculetin-induced inhibition of vascular smooth muscle cells proliferation.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20111001
Title: Activation by 2-arachidonoylglycerol of platelet p38MAPK/cPLA2 pathway.
Journal: Journal of cellular biochemistry 20111001
Title: Peroxisome proliferator-activated receptor γ (PPARγ) plays a critical role in the development of TGFβ resistance of H460 cell.
Journal: Cellular signalling 20111001
Title: iNOS/NO signaling regulates apoptosis induced by glycochenodeoxycholate in hepatocytes.
Journal: Cellular signalling 20111001
Title: Inhibition of neutrophil apoptosis via sphingolipid signaling in acute lung injury.
Journal: The Journal of pharmacology and experimental therapeutics 20111001
Title: Gefitinib attenuates transforming growth factor-β1-activated mitogen-activated protein kinases and mitogenesis in NRK-49F cells.
Journal: Translational research : the journal of laboratory and clinical medicine 20111001
Title: Increased p38 mitogen-activated protein kinase signaling is involved in the oxidative stress associated with oxygen and glucose deprivation in neonatal hippocampal slice cultures.
Journal: The European journal of neuroscience 20111001
Title: The cross-talk between ROS and p38MAPKα in the Ex Vivo expanded human umbilical cord blood CD133(+) cells.
Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20111001
Title: The p38 MAPK inhibitor SB203580 induces cytochrome P450 1A1 gene expression in murine and human hepatoma cell lines through ligand-dependent aryl hydrocarbon receptor activation.
Journal: Chemical research in toxicology 20110919
Title: Adventitia-derived hydrogen peroxide impairs relaxation of the rat carotid artery via smooth muscle cell p38 mitogen-activated protein kinase.
Journal: Antioxidants & redox signaling 20110915
Title: Regional difference in inflammatory response to LPS-injection in the brain: role of microglia cell density.
Journal: Journal of neuroimmunology 20110915
Title: Study on glucose transport in muscle cells by extracts from Mitragyna speciosa (Korth) and mitragynine.
Journal: Natural product research 20110901
Title: Neuroprotective effect of ligustilide against ischaemia-reperfusion injury via up-regulation of erythropoietin and down-regulation of RTP801.
Journal: British journal of pharmacology 20110901
Title: Angiotensin II type 1 receptor signalling regulates microRNA differentially in cardiac fibroblasts and myocytes.
Journal: British journal of pharmacology 20110901
Title: The selective p38 mitogen-activated protein kinase inhibitor, SB203580, improves renal disease in MRL/lpr mouse model of systemic lupus.
Journal: International immunopharmacology 20110901
Title: Arsenic trioxide induces autophagy and apoptosis in human glioma cells in vitro and in vivo through downregulation of survivin.
Journal: Journal of molecular medicine (Berlin, Germany) 20110901
Title: Polycyclic aromatic hydrocarbons induce migration in human hepatocellular carcinoma cells (HepG2) through reactive oxygen species-mediated p38 MAPK signal transduction.
Journal: Cancer science 20110901
Title: Reactive oxygen species participate in the p38-mediated apoptosis induced by potassium deprivation and staurosporine in cerebellar granule neurons.
Journal: The international journal of biochemistry & cell biology 20110901
Title: Human apolipoprotein A-I induces cyclooxygenase-2 expression and prostaglandin I-2 release in endothelial cells through ATP-binding cassette transporter A1.
Journal: American journal of physiology. Cell physiology 20110901
Title: tPA contributes to impaired NMDA cerebrovasodilation after traumatic brain injury through activation of JNK MAPK.
Journal: Neurological research 20110901
Title: Arsenic increases lipopolysaccharide-dependent expression of interleukin-8 gene by stimulating a redox-sensitive pathway that strengthens p38-kinase activation.
Journal: Molecular immunology 20110901
Title: Transforming growth factor-beta1 (TGF-beta1) utilizes distinct pathways for the transcriptional activation of microRNA 143/145 in human coronary artery smooth muscle cells.
Journal: The Journal of biological chemistry 20110826
Title: 2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced MUC5AC expression: aryl hydrocarbon receptor-independent/EGFR/ERK/p38-dependent SP1-based transcription.
Journal: American journal of respiratory cell and molecular biology 20110801
Title: Lipopolysaccharide and platelet-activating factor stimulate expression of platelet-activating factor acetylhydrolase via distinct signaling pathways.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20110801
Title: Adiponectin attenuates hypoxia/reoxygenation-induced cardiomyocyte injury through inhibition of endoplasmic reticulum stress.
Journal: Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20110801
Title: Chemical chaperones protect epidermolysis bullosa simplex keratinocytes from heat stress-induced keratin aggregation: involvement of heat shock proteins and MAP kinases.
Journal: The Journal of investigative dermatology 20110801
Title: Resistin induces monocyte-endothelial cell adhesion by increasing ICAM-1 and VCAM-1 expression in endothelial cells via p38MAPK-dependent pathway.
Journal: Journal of cellular physiology 20110801
Title: Intraplantar-injected ceramide in rats induces hyperalgesia through an NF-κB- and p38 kinase-dependent cyclooxygenase 2/prostaglandin E2 pathway.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110801
Title: Defective nuclear translocation of stress-activated signaling in senescent diploid human fibroblasts: a possible explanation for aging-associated apoptosis resistance.
Journal: Apoptosis : an international journal on programmed cell death 20110801
Title: Effects of downregulation of aquaporin1 by peptidoglycan and lipopolysaccharide via MAPK pathways in MeT-5A cells.
Journal: Lung 20110801
Title: The ETS family transcription factor ELK-1 regulates induction of the cell cycle-regulatory gene p21(Waf1/Cip1) and the BAX gene in sodium arsenite-exposed human keratinocyte HaCaT cells.
Journal: The Journal of biological chemistry 20110729
Title: Specificity protein-1 as a critical regulator of human cystathionine gamma-lyase in smooth muscle cells.
Journal: The Journal of biological chemistry 20110729
Title: Indolin-2-one p38α inhibitors I: design, profiling and crystallographic binding mode.
Journal: Bioorganic & medicinal chemistry letters 20110715
Title: Nickel promotes the invasive potential of human lung cancer cells via TLR4/MyD88 signaling.
Journal: Toxicology 20110711
Title: Distinct functions of the mitogen-activated protein kinase-activated protein (MAPKAP) kinases MK2 and MK3: MK2 mediates lipopolysaccharide-induced signal transducers and activators of transcription 3 (STAT3) activation by preventing negative regulatory effects of MK3.
Journal: The Journal of biological chemistry 20110708
Title: Sulfur mustard induces differentiation in human primary keratinocytes: opposite roles of p38 and ERK1/2 MAPK.
Journal: Toxicology letters 20110704
Title: Involvement of oxidative stress-mediated ERK1/2 and p38 activation regulated mitochondria-dependent apoptotic signals in methylmercury-induced neuronal cell injury.
Journal: Toxicology letters 20110704
Title: Dermal fibroblasts influence the expression profile of 14-3-3 proteins in human keratinocytes.
Journal: Molecular and cellular biochemistry 20110701
Title: Globular adiponectin improves high glucose-suppressed endothelial progenitor cell function through endothelial nitric oxide synthase dependent mechanisms.
Journal: Journal of molecular and cellular cardiology 20110701
Title: CXCL2 mediates lipopolysaccharide-induced osteoclastogenesis in RANKL-primed precursors.
Journal: Cytokine 20110701
Title: Berberine acutely activates the glucose transport activity of GLUT1.
Journal: Biochimie 20110701
Title: Role of P2X4 receptors in synaptic strengthening in mouse CA1 hippocampal neurons.
Journal: The European journal of neuroscience 20110701
Title: T-2 toxin is a cytochrome P450 1A1 inducer and leads to MAPK/p38- but not aryl hydrocarbon receptor-dependent interleukin-8 secretion in the human intestinal epithelial cell line Caco-2.
Journal: Toxicology 20110618
Title: Roles of mitogen-activated protein kinases in the modulation of endothelial cell function following thermal injury.
Journal: Shock (Augusta, Ga.) 20110601
Title: Human p38 mitogen-activated protein kinase inhibitor drugs inhibit Plasmodium falciparum replication.
Journal: Experimental parasitology 20110601
Title: The signalling axis mediating neuronal apoptosis in response to [Pt(O,O'-acac)(γ-acac)(DMS)].
Journal: Biochemical pharmacology 20110601
Title: Discovery, synthesis, and investigation of the antitumor activity of novel piperazinylpyrimidine derivatives.
Journal: European journal of medicinal chemistry 20110601
Title: Differential roles of MAPK-Erk1/2 and MAPK-p38 in insulin or insulin-like growth factor-I (IGF-I) signaling pathways for progesterone production in human ovarian cells.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20110601
Title: Regulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide.
Journal: Toxicology and applied pharmacology 20110601
Title: Imatinib mesylate induction of ROS-dependent apoptosis in melanoma B16F0 cells.
Journal: Journal of dermatological science 20110601
Title: Pre-B cell colony-enhancing factor (PBEF/Nampt/visfatin) primes neutrophils for augmented respiratory burst activity through partial assembly of the NADPH oxidase.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20110601
Title: Suppression of phorbol-12-myristate-13-acetate-induced tumor cell invasion by piperine via the inhibition of PKCα/ERK1/2-dependent matrix metalloproteinase-9 expression.
Journal: Toxicology letters 20110530
Title: Ubiquitous hazardous metal lead induces TNF-α in human phagocytic THP-1 cells: primary role of ERK 1/2.
Journal: Journal of hazardous materials 20110515
Title: Transcriptional suppression of IL-27 production by Mycobacterium tuberculosis-activated p38 MAPK via inhibition of AP-1 binding.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20110515
Title: Chiral sulfoxides as metabolites of 2-thioimidazole-based p38α mitogen-activated protein kinase inhibitors: enantioselective synthesis and biological evaluation.
Journal: Journal of medicinal chemistry 20110512
Title: Down-regulation of cytokine-induced interleukin-8 requires inhibition of p38 mitogen-activated protein kinase (MAPK) via MAPK phosphatase 1-dependent and -independent mechanisms.
Journal: The Journal of biological chemistry 20110506
Title: Role of estrogen receptor-dependent upregulation of P38 MAPK/heme oxygenase 1 in resveratrol-mediated attenuation of intestinal injury after trauma-hemorrhage.
Journal: Shock (Augusta, Ga.) 20110501
Title: Hydrogen peroxide depletes phosphatidylinositol-3-phosphate from endosomes in a p38 MAPK-dependent manner and perturbs endocytosis.
Journal: Biochimica et biophysica acta 20110501
Title: Angiotensin II-induced vascular endothelial dysfunction through RhoA/Rho kinase/p38 mitogen-activated protein kinase/arginase pathway.
Journal: American journal of physiology. Cell physiology 20110501
Title: Regulation of transforming growth factor-β1-dependent integrin β6 expression by p38 mitogen-activated protein kinase in bile duct epithelial cells.
Journal: The Journal of pharmacology and experimental therapeutics 20110501
Title: Preconditioning effects of tumor necrosis factor-α and glutamate on calcium dynamics in rat organotypic hippocampal cultures.
Journal: Journal of neuroimmunology 20110501
Title: Genipa americana (Rubiaceae) fruit extract affects mitogen-activated protein kinase cell pathways in human trophoblast-derived BeWo cells: implications for placental development.
Journal: Journal of medicinal food 20110501
Title: c-Jun NH₂-terminal kinase contributes to dexmedetomidine-induced contraction in isolated rat aortic smooth muscle.
Journal: Yonsei medical journal 20110501
Title: Reactive oxygen species hydrogen peroxide mediates Kaposi's sarcoma-associated herpesvirus reactivation from latency.
Journal: PLoS pathogens 20110501
Title: Bupivacaine induces apoptosis via mitochondria and p38 MAPK dependent pathways.
Journal: European journal of pharmacology 20110425
Title: 5-Hydroxytryptamine induces cyclooxygenase-2 in rat vascular smooth muscle cells: Mechanisms involving Src, PKC and MAPK activation [corrected].
Journal: European journal of pharmacology 20110410
Title: Selenium inhibits high glucose-induced cyclooxygenase-2 and P-selectin expression in vascular endothelial cells.
Journal: Molecular biology reports 20110401
Title: Glycine-induced cytoprotection is mediated by ERK1/2 and AKT in renal cells with ATP depletion.
Journal: European journal of cell biology 20110401
Title: Lithospermic acid B protects β-cells from cytokine-induced apoptosis by alleviating apoptotic pathways and activating anti-apoptotic pathways of Nrf2-HO-1 and Sirt1.
Journal: Toxicology and applied pharmacology 20110401
Title: p38 mitogen-activated protein kinase-dependent transactivation of ErbB receptor family: a novel common mechanism for stress-induced IRS-1 serine phosphorylation and insulin resistance.
Journal: Diabetes 20110401
Title: [Effect and mechanism of matrine on apoptosis of Raji cells].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20110401
Title: Lipopolysaccharide down-regulates carbolesterases 1 and 2 and reduces hydrolysis activity in vitro and in vivo via p38MAPK-NF-κB pathway.
Journal: Toxicology letters 20110325
Title: Upregulation of heme oxygenase-1 as an adaptive mechanism for protection against crotonaldehyde in human umbilical vein endothelial cells.
Journal: Toxicology letters 20110325
Title: Involvement of p38/NF-κB signaling pathway in the nucleus accumbens in the rewarding effects of morphine in rats.
Journal: Behavioural brain research 20110317
Title: Cadmium induces phosphorylation and stabilization of c-Fos in HK-2 renal proximal tubular cells.
Journal: Toxicology and applied pharmacology 20110315
Title: Involvement of heme oxygenase-1 induction via Nrf2/ARE activation in protection against H2O2-induced PC12 cell death by a metabolite of sesamin contained in sesame seeds.
Journal: Bioorganic & medicinal chemistry 20110315
Title: Apoptosis induced by a new flavonoid in human hepatoma HepG2 cells involves reactive oxygen species-mediated mitochondrial dysfunction and MAPK activation.
Journal: European journal of pharmacology 20110311
Title: Stimulation of pro-inflammatory responses by mebendazole in human monocytic THP-1 cells through an ERK signaling pathway.
Journal: Archives of toxicology 20110301
Title: Tanshinone IIA acts via p38 MAPK to induce apoptosis and the down-regulation of ERCC1 and lung-resistance protein in cisplatin-resistant ovarian cancer cells.
Journal: Oncology reports 20110301
Title: Ondansetron attenuates hepatic injury via p38 MAPK-dependent pathway in a rat haemorrhagic shock model.
Journal: Resuscitation 20110301
Title: Diosgenin induces death receptor-5 through activation of p38 pathway and promotes TRAIL-induced apoptosis in colon cancer cells.
Journal: Cancer letters 20110227
Title: Neuroprotective effects of icariin on corticosterone-induced apoptosis in primary cultured rat hippocampal neurons.
Journal: Brain research 20110223
Title: Mitogen-activated protein kinases ERK 1/2- and p38-GATA4 pathways mediate the Ang II-induced activation of FGF2 gene in neonatal rat cardiomyocytes.
Journal: Biochemical pharmacology 20110215
Title: Advanced glycation end products induce moesin phosphorylation in murine brain endothelium.
Journal: Brain research 20110210
Title: Differential activation of signaling pathways involved in cell death, survival and inflammation by radiocontrast media in human renal proximal tubular cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110201
Title: Norcantharidin induces cell cycle arrest and inhibits progression of human leukemic Jurkat T cells through mitogen-activated protein kinase-mediated regulation of interleukin-2 production.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20110201
Title: Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism.
Journal: Apoptosis : an international journal on programmed cell death 20110201
Title: RNA-binding protein AUF1 regulates lipopolysaccharide-induced IL10 expression by activating IkappaB kinase complex in monocytes.
Journal: Molecular and cellular biology 20110201
Title: High glucose induces enhanced expression of resistin in human U937 monocyte-like cell line by MAPK- and NF-kB-dependent mechanisms; the modulating effect of insulin.
Journal: Cell and tissue research 20110201
Title: Anticancer activity of a combination of cisplatin and fisetin in embryonal carcinoma cells and xenograft tumors.
Journal: Molecular cancer therapeutics 20110201
Title: Signalling pathways responsible for the methylisogermabullone-induced contraction of ileal longitudinal muscles.
Journal: The Journal of pharmacy and pharmacology 20110201
Title: NADPH oxidase 4 mediates TGF-β-induced smooth muscle α-actin via p38MAPK and serum response factor.
Journal: Free radical biology & medicine 20110115
Title: MAPK signaling in H9c2 cardiomyoblasts exposed to cholesterol secoaldehyde--role of hydrogen peroxide.
Journal: Biochemical and biophysical research communications 20110107
Title: Down-regulation of connexin43 gap junction by serum deprivation in human endothelial cells was improved by (-)-Epigallocatechin gallate via ERK MAP kinase pathway.
Journal: Biochemical and biophysical research communications 20110107
Title: Suppression of Heregulin-β1/HER2-Modulated Invasive and Aggressive Phenotype of Breast Carcinoma by Pterostilbene via Inhibition of Matrix Metalloproteinase-9, p38 Kinase Cascade and Akt Activation.
Journal: Evidence-based complementary and alternative medicine : eCAM 20110101
Title: Poly(I:C) reduces expression of JAM-A and induces secretion of IL-8 and TNF-α via distinct NF-κB pathways in human nasal epithelial cells.
Journal: Toxicology and applied pharmacology 20110101
Title: C-reactive protein impairs hepatic insulin sensitivity and insulin signaling in rats: role of mitogen-activated protein kinases.
Journal: Hepatology (Baltimore, Md.) 20110101
Title: Key roles of endothelin-1 and p38 MAPK in the regulation of atrial stretch response.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20110101
Title: Mycoplasma hyopneumoniae induces pro-inflammatory cytokine and nitric oxide production through NFκB and MAPK pathways in RAW264.7 cells.
Journal: Veterinary research communications 20110101
Title: Lactobacillus casei prevents impaired barrier function in intestinal epithelial cells.
Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20110101
Title: [The relationship between reactive oxygen species-dependent activation of p38 MAPK and the expression of tumor necrosis factor-α in cultured cardiomyocytes].
Journal: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20110101
Title: A role for p38 MAPK in the regulation of ciliary motion in a eukaryote.
Journal: BMC cell biology 20110101
Title: Angiotensin II induces the expression of c-reactive protein via MAPK-dependent signal pathway in U937 macrophages.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101
Title: High-Glucose Environment Inhibits p38MAPK Signaling and Reduces Human β-Defensin-3 Expression [corrected] in Keratinocytes.
Journal: Molecular medicine (Cambridge, Mass.) 20110101
Title: All-trans-retinoic acid and Erk1/2 signaling synergistically regulate the expression of CD300B in human monocytic cells.
Journal: Cellular immunology 20110101
Title: Transforming growth factor β1 promotes migration of human periodontal ligament cells through heat shock protein 27 phosphorylation.
Journal: Biological & pharmaceutical bulletin 20110101
Title: Attenuated expression and function of the RECK tumor suppressor under hypoxic conditions is mediated by the MAPK signaling pathways.
Journal: Archives of pharmacal research 20110101
Title: CP690,550 inhibits oncostatin M-induced JAK/STAT signaling pathway in rheumatoid synoviocytes.
Journal: Arthritis research & therapy 20110101
Title: A redox microenvironment is essential for MAPK-dependent secretion of pro-inflammatory cytokines: modulation by glutathione (GSH/GSSG) biosynthesis and equilibrium in the alveolar epithelium.
Journal: Cellular immunology 20110101
Title: Toll-like receptor 9 is required for opioid-induced microglia apoptosis.
Journal: PloS one 20110101
Title: Antigen-independent IFN-γ production by human naïve CD4 T cells activated by IL-12 plus IL-18.
Journal: PloS one 20110101
Title: Suppression of MMP-2 attenuates TNF-α induced NF-κB activation and leads to JNK mediated cell death in glioma.
Journal: PloS one 20110101
Title: AGE-BSA down-regulates endothelial connexin43 gap junctions.
Journal: BMC cell biology 20110101
Title: 8-Chloro-cyclic AMP and protein kinase A I-selective cyclic AMP analogs inhibit cancer cell growth through different mechanisms.
Journal: PloS one 20110101
Title: Possible underlying influence of p38MAPK and NF-κB in the diminished anti-anxiety effect of diazepam in stressed mice.
Journal: Journal of pharmacological sciences 20110101
Title: Resveratrol inhibits Cdk5 activity through regulation of p35 expression.
Journal: Molecular pain 20110101
Title: A uremic solute, P-cresol, inhibits the proliferation of endothelial progenitor cells via the p38 pathway.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101
Title: Behavioral evidence for the differential regulation of p-p38 MAPK and p-NF-κB in rats with trigeminal neuropathic pain.
Journal: Molecular pain 20110101
Title: Factors influencing RhoA protein distribution in the nucleus.
Journal: Molecular medicine reports 20110101
Title: Panax notoginseng saponins promote osteogenic differentiation of bone marrow stromal cells through the ERK and P38 MAPK signaling pathways.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101
Title: On the possible role of ERK, p38 and CaMKII in the regulation of CGRP expression in morphine-tolerant rats.
Journal: Molecular pain 20110101
Title: Effect of simvastatin on expression of transforming growth factor-β and collagen type IV in rat mesangial cells.
Journal: Pharmacology 20110101
Title: Hydrogen sulfide protects against chemical hypoxia-induced injury by inhibiting ROS-activated ERK1/2 and p38MAPK signaling pathways in PC12 cells.
Journal: PloS one 20110101
Title: Inhibition of p38-MAPK signaling pathway attenuates breast cancer induced bone pain and disease progression in a murine model of cancer-induced bone pain.
Journal: Molecular pain 20110101
Title: Carbon monoxide induced PPARγ SUMOylation and UCP2 block inflammatory gene expression in macrophages.
Journal: PloS one 20110101
Title: p38 MAPK activation and function following osmotic shock of erythrocytes.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101
Title: Activation of the p38 MAPK/Akt/ERK1/2 signal pathways is required for the protein stabilization of CDC6 and cyclin D1 in low-dose arsenite-induced cell proliferation.
Journal: Journal of cellular biochemistry 20101215
Title: Parathyroid hormone(1-34)-induced apoptosis in neuronal rat PC12 cells: implications for neurotoxicity.
Journal: Pathology, research and practice 20101215
Title: VEGF protects spinal motor neurons against chronic excitotoxic degeneration in vivo by activation of PI3-K pathway and inhibition of p38MAPK.
Journal: Journal of neurochemistry 20101201
Title: Effect of phosphatidyl inositol 3-kinase, extracellular signal-regulated kinases 1/2, and p38 mitogen-activated protein kinase inhibition on osteogenic differentiation of muscle-derived stem cells.
Journal: Tissue engineering. Part A 20101201
Title: Mechanism of activation of PKB/Akt by the protein phosphatase inhibitor Calyculin A.
Journal: Cell biochemistry and biophysics 20101201
Title: p38 Mitogen-activated protein kinase (MAPK) increases arginase activity and contributes to endothelial dysfunction in corpora cavernosa from angiotensin-II-treated mice.
Journal: The journal of sexual medicine 20101201
Title: Interleukin-1 receptor activation by systemic lipopolysaccharide induces behavioral despair linked to MAPK regulation of CNS serotonin transporters.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20101201
Title: Effects and mechanisms of nonylphenol on corticosterone release in rat zona fasciculata-reticularis cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20101201
Title: A novel cell permeant peptide inhibitor of MAPKAP kinase II inhibits intimal hyperplasia in a human saphenous vein organ culture model.
Journal: Journal of vascular surgery 20101201
Title: Rhizoctonia bataticola lectin (RBL) induces mitogenesis and cytokine production in human PBMC via p38 MAPK and STAT-5 signaling pathways.
Journal: Biochimica et biophysica acta 20101201
Title: Carbazoles and coumarins from Clausena harmandiana stimulate glucose uptake in L6 myotubes.
Journal: Diabetes research and clinical practice 20101201
Title: Integrin β3 and its ligand regulate the expression of uPA through p38 MAPK in breast cancer.
Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20101201
Title: Duplicate preconditioning with sevoflurane in vitro improves neuroprotection in rat brain via activating the extracellular signal-regulated protein kinase.
Journal: Neuroscience bulletin 20101201
Title: Cloning and characterization of a novel gene with alternative splicing in murine mesenchymal stem cell line C3H/10T1/2 by gene trap screening.
Journal: BMB reports 20101201
Title: Activation state-dependent binding of small molecule kinase inhibitors: structural insights from biochemistry.
Journal: Chemistry & biology 20101124
Title: Lupane-type triterpenoids from the steamed leaves of Acanthopanax koreanum and their inhibitory effects on the LPS-stimulated pro-inflammatory cytokine production in bone marrow-derived dendritic cells.
Journal: Bioorganic & medicinal chemistry letters 20101115
Title: Synthesis and biological analysis of prostate-specific membrane antigen-targeted anticancer prodrugs.
Journal: Journal of medicinal chemistry 20101111
Title: Gefitinib enhances arsenic trioxide (AS2O3)-induced differentiation of acute promyelocytic leukemia cell line.
Journal: Leukemia research 20101101
Title: Glycogen synthase kinase-3 and p38 MAPK are required for opioid-induced microglia apoptosis.
Journal: Neuropharmacology 20101101
Title: Activation of the p38 pathway by a novel monoketone curcumin analog, EF24, suggests a potential combination strategy.
Journal: Biochemical pharmacology 20101101
Title: Induction of apoptosis by HAC-Y6, a novel microtubule inhibitor, through activation of the death receptor 4 signaling pathway in human hepatocellular carcinoma cells.
Journal: Oncology reports 20101101
Title: Myricetin reduces voltage activated potassium channel currents in DRG neurons by a p38 dependent mechanism.
Journal: Brain research bulletin 20101030
Title: 3-Caffeoyl, 4-dihydrocaffeoylquinic acid from Salicornia herbacea inhibits tumor cell invasion by regulating protein kinase C-delta-dependent matrix metalloproteinase-9 expression.
Journal: Toxicology letters 20101005
Title: Biochemical and biophysical characterization of unique switch pocket inhibitors of p38α.
Journal: Bioorganic & medicinal chemistry letters 20101001
Title: Physio-pathological parameters affect the activation of inflammatory pathways by deoxynivalenol in Caco-2 cells.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20101001
Title: Epigallocatechin gallate inhibits angiotensin II-induced endothelial barrier dysfunction via inhibition of the p38 MAPK/HSP27 pathway.
Journal: Acta pharmacologica Sinica 20101001
Title: Preeclampsia-related increase of interleukin-11 expression in human decidual cells.
Journal: Reproduction (Cambridge, England) 20101001
Title: Down-regulation of p38 mitogen-activated protein kinase activation and proinflammatory cytokine production by mitogen-activated protein kinase inhibitors in inflammatory bowel disease.
Journal: Clinical and experimental immunology 20101001
Title: [Simvastatin suppress lipopolysaccharides induced upregulation of lipoprotein associated phospholipase A(2) expression in macrophages via inactivation of p38MAPK pathway].
Journal: Zhonghua xin xue guan bing za zhi 20101001
Title: Simvastatin-dependent up-regulation of heme oxygenase-1 via mRNA stabilization in human endothelial cells.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100911
Title: Lipid soluble smoke particles upregulate endothelin receptors in rat basilar artery.
Journal: Toxicology letters 20100901
Title: Negative modulation of invariant natural killer T cell responses to glycolipid antigens by p38 MAP kinase.
Journal: International immunopharmacology 20100901
Title: Multiple protein kinase pathways mediate amplified IL-6 release by human lung fibroblasts co-exposed to nickel and TLR-2 agonist, MALP-2.
Journal: Toxicology and applied pharmacology 20100901
Title: Down-regulation of MMP-2 through the p38 MAPK-NF-kappaB-dependent pathway by aloe-emodin leads to inhibition of nasopharyngeal carcinoma cell invasion.
Journal: Molecular carcinogenesis 20100901
Title: Essential role for p38alpha MAPK but not p38gamma MAPK in Igf2 expression and myoblast differentiation.
Journal: Endocrinology 20100901
Title: Ovarian steroids, mitogen-activated protein kinases, and/or aspartic proteinases cooperate to control endometrial remodeling by regulating gene expression in the stroma and glands.
Journal: Endocrinology 20100901
Title: Lidocaine attenuates proinflammatory cytokine production induced by extracellular adenosine triphosphate in cultured rat microglia.
Journal: Anesthesia and analgesia 20100901
Title: MAP kinase-signaling controls nuclear translocation of tripeptidyl-peptidase II in response to DNA damage and oxidative stress.
Journal: Biochemical and biophysical research communications 20100827
Title: Nav1.7-Ca2+ influx-induced increased phosphorylations of extracellular signal-regulated kinase (ERK) and p38 attenuate tau phosphorylation via glycogen synthase kinase-3beta: priming of Nav1.7 gating by ERK and p38.
Journal: European journal of pharmacology 20100825
Title: Heme oxygenase-1 contributes to pathology associated with thrombin-induced striatal and cortical injury in organotypic slice culture.
Journal: Brain research 20100806
Title: The P38alpha and P38delta MAP kinases may be gene therapy targets in the future treatment of severe burns.
Journal: Shock (Augusta, Ga.) 20100801
Title: Pyrogallol-induced As4.1 juxtaglomerular cell death is attenuated by MAPK inhibitors via preventing GSH depletion.
Journal: Archives of toxicology 20100801
Title: Oxidized low-density lipoprotein increases interleukin-8 production in human gingival epithelial cell line Ca9-22.
Journal: Journal of periodontal research 20100801
Title: Activation of p38 MAPK participates in brain ischemic tolerance induced by limb ischemic preconditioning by up-regulating HSP 70.
Journal: Experimental neurology 20100801
Title: Impaired dephosphorylation renders G6PD-knockdown HepG2 cells more susceptible to H(2)O(2)-induced apoptosis.
Journal: Free radical biology & medicine 20100801
Title: Betulinic acid isolated from Bacopa monniera (L.) Wettst suppresses lipopolysaccharide stimulated interleukin-6 production through modulation of nuclear factor-kappaB in peripheral blood mononuclear cells.
Journal: International immunopharmacology 20100801
Title: Celastrol acts as a potent antimetastatic agent targeting beta1 integrin and inhibiting cell-extracellular matrix adhesion, in part via the p38 mitogen-activated protein kinase pathway.
Journal: The Journal of pharmacology and experimental therapeutics 20100801
Title: Novel plasminogen activator inhibitor-1-derived peptide protects against impairment of cerebrovasodilation after photothrombosis through inhibition of JNK MAPK.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20100801
Title: Trans-Zeatin attenuates ultraviolet induced down-regulation of aquaporin-3 in cultured human skin keratinocytes.
Journal: International journal of molecular medicine 20100801
Title: p38 inhibitor enhances growth inhibition and death in gallic acid-treated endothelial cells.
Journal: International journal of molecular medicine 20100801
Title: Transforming growth factor beta1-induced heat shock protein 27 activation promotes migration of mouse dental papilla-derived MDPC-23 cells.
Journal: Journal of endodontics 20100801
Title: ES936 stimulates DNA synthesis in HeLa cells independently on NAD(P)H:quinone oxidoreductase 1 inhibition, through a mechanism involving p38 MAPK.
Journal: Chemico-biological interactions 20100730
Title: Tibia tumor-induced cancer pain involves spinal p38 mitogen-activated protein kinase activation via TLR4-dependent mechanisms.
Journal: Brain research 20100730
Title: HSP27 controls GATA-1 protein level during erythroid cell differentiation.
Journal: Blood 20100708
Title: Synthesis and biological testing of N-aminoimidazole-based p38alpha MAP kinase inhibitors.
Journal: ChemMedChem 20100705
Title: Amphetamines induce tissue factor and impair tissue factor pathway inhibitor: role of dopamine receptor type 4.
Journal: European heart journal 20100701
Title: Mycophenolic acid attenuates tumor necrosis factor-alpha-induced endothelin-1 production in human aortic endothelial cells.
Journal: Atherosclerosis 20100701
Title: Cadmium-induced hormetic effect in differentiated Caco-2 cells: ERK and p38 activation without cell proliferation stimulation.
Journal: Journal of cellular physiology 20100701
Title: PAI-1-derived peptide EEIIMD prevents impairment of cerebrovasodilation by augmenting p38 MAPK upregulation after cerebral hypoxia/ischemia.
Journal: American journal of physiology. Heart and circulatory physiology 20100701
Title: Structure of the EGF receptor transactivation circuit integrates multiple signals with cell context.
Journal: Molecular bioSystems 20100701
Title: Deciphering mechanisms controlling placental artery endothelial cell migration stimulated by vascular endothelial growth factor.
Journal: Endocrinology 20100701
Title: Mechanisms of IL-12 synthesis by human dendritic cells treated with the chemical sensitizer NiSO4.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20100701
Title: Unexpected reaction of 2-alkylsulfanylimidazoles to imidazol-2-ones: pyridinylimidazol-2-ones as novel potent p38alpha mitogen-activated protein kinase inhibitors.
Journal: Journal of medicinal chemistry 20100624
Title: Involvement of prostaglandins and histamine in nickel wire-induced acute inflammation in mice.
Journal: Journal of biomedical materials research. Part A 20100615
Title: Suppression of PMA-induced tumor cell invasion by dihydroartemisinin via inhibition of PKCalpha/Raf/MAPKs and NF-kappaB/AP-1-dependent mechanisms.
Journal: Biochemical pharmacology 20100615
Title: Role of MAP kinases in regulating expression of antioxidants and inflammatory mediators in mouse keratinocytes following exposure to the half mustard, 2-chloroethyl ethyl sulfide.
Journal: Toxicology and applied pharmacology 20100615
Title: Novel p38 MAPK inhibitor ML3403 has potent anti-inflammatory activity in airway smooth muscle.
Journal: European journal of pharmacology 20100610
Title: Glucosamine regulation of LPS-mediated inflammation in human bronchial epithelial cells.
Journal: European journal of pharmacology 20100610
Title: Manganese-mediated up-regulation of HIF-1alpha protein in Hep2 human laryngeal epithelial cells via activation of the family of MAPKs.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100601
Title: Fluorescence polarization binding assay to develop inhibitors of inactive p38alpha mitogen-activated protein kinase.
Journal: Analytical biochemistry 20100601
Title: The activation of p38 alpha, and not p38 beta, mitogen-activated protein kinase is required for ischemic preconditioning.
Journal: Journal of molecular and cellular cardiology 20100601
Title: Ketamine reduces inducible superoxide generation in human neutrophils in vitro by modulating the p38 mitogen-activated protein kinase (MAPK)-mediated pathway.
Journal: Clinical and experimental immunology 20100601
Title: Deferoxamine mesylate is toxic for retinal pigment epithelium cells in vitro, and its toxicity is mediated by p38.
Journal: Cutaneous and ocular toxicology 20100601
Title: Secreted phosphoprotein 1 binds integrins to initiate multiple cell signaling pathways, including FRAP1/mTOR, to support attachment and force-generated migration of trophectoderm cells.
Journal: Matrix biology : journal of the International Society for Matrix Biology 20100601
Title: Astrocytic activation and an inhibition of MAP kinases are required for proteinase-activated receptor-2-mediated protection from neurotoxicity.
Journal: Journal of neurochemistry 20100601
Title: The effect of midazolam on neutrophil mitogen-activated protein kinase.
Journal: European journal of anaesthesiology 20100601
Title: Treatment with p38 inhibitor partially prevents Calu-6 lung cancer cell death by a proteasome inhibitor, MG132.
Journal: Cancer genetics and cytogenetics 20100601
Title: Formaldehyde induces apoptosis through decreased Prx 2 via p38 MAPK in lung epithelial cells.
Journal: Toxicology 20100527
Title: Regulation of plasminogen activator inhibitor-1 expression in endothelial cells with exposure to metal nanoparticles.
Journal: Toxicology letters 20100519
Title: Rapid effects of phytoestrogens on human colonic smooth muscle are mediated by oestrogen receptor beta.
Journal: Molecular and cellular endocrinology 20100514
Title: Inhibition of p38 MAPK improves intestinal disturbances and oxidative stress induced in a rabbit endotoxemia model.
Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20100501
Title: Nitric oxide stimulates interleukin-6 production in skeletal myotubes.
Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20100501
Title: Cyclic AMP stimulates Mrp2 translocation by activating p38{alpha} MAPK in hepatic cells.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20100501
Title: Palmitic acid promotes endothelial progenitor cells apoptosis via p38 and JNK mitogen-activated protein kinase pathways.
Journal: Atherosclerosis 20100501
Title: Stimulatory effects of areca nut extracts on prostaglandin E2 production by human polymorphonuclear leukocytes.
Journal: Journal of periodontology 20100501
Title: Differential modulation of lipopolysaccharide-induced expression of inflammatory genes in equine monocytes through activation of adenosine A2A receptors.
Journal: Veterinary immunology and immunopathology 20100415
Title: Cinnamaldehyde impairs high glucose-induced hypertrophy in renal interstitial fibroblasts.
Journal: Toxicology and applied pharmacology 20100415
Title: Activation of the nucleotide oligomerization domain signaling pathway by the non-bacterially derived xanthone drug 5'6-dimethylxanthenone-4-acetic acid (Vadimezan).
Journal: The Journal of biological chemistry 20100402
Title: Particulate matter disrupts human lung endothelial barrier integrity via ROS- and p38 MAPK-dependent pathways.
Journal: American journal of respiratory cell and molecular biology 20100401
Title: Mycophenolic acid inhibits albumin-induced MCP-1 expression in renal tubular epithelial cells through the p38 MAPK pathway.
Journal: Molecular biology reports 20100401
Title: The role of p38 mitogen-activated protein kinase in serum-induced leukemia inhibitory factor secretion by bone marrow stromal cells from pediatric myelodysplastic syndromes.
Journal: Leukemia research 20100401
Title: Hyperforin induces Ca(2+)-independent arachidonic acid release in human platelets by facilitating cytosolic phospholipase A(2) activation through select phospholipid interactions.
Journal: Biochimica et biophysica acta 20100401
Title: Stimulation of adenosine A(2B) receptors induces interleukin-6 secretion in cardiac fibroblasts via the PKC-delta-P38 signalling pathway.
Journal: British journal of pharmacology 20100401
Title: Carbon monoxide releasing molecule-2 inhibits pancreatic stellate cell proliferation by activating p38 mitogen-activated protein kinase/heme oxygenase-1 signaling.
Journal: Molecular pharmacology 20100401
Title: Different activation forms of MMP-2 oppositely affect the fate of endothelial cells.
Journal: American journal of physiology. Cell physiology 20100401
Title: Distinct effects of p38alpha deletion in myeloid lineage and gut epithelia in mouse models of inflammatory bowel disease.
Journal: Gastroenterology 20100401
Title: Hyperglycemia suppresses ABCA1 expression in vascular smooth muscle cells.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20100401
Title: YC-1 enhances natural killer cell differentiation from hematopoietic stem cells.
Journal: International immunopharmacology 20100401
Title: Insulin-like growth factors are more effective than progastrin in reversing proapoptotic effects of curcumin: critical role of p38MAPK.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20100401
Title: [IL-27 regulates the expression of Mac-1, fMLP-R and IL-1beta in human neutrophils through p38 MAPK and PI3K signal pathways].
Journal: Zhongguo shi yan xue ye xue za zhi 20100401
Title: Proinflammatory effects of muramyldipeptide on human gingival fibroblasts.
Journal: Journal of periodontal research 20100401
Title: Purification of a peptide from seahorse, that inhibits TPA-induced MMP, iNOS and COX-2 expression through MAPK and NF-kappaB activation, and induces human osteoblastic and chondrocytic differentiation.
Journal: Chemico-biological interactions 20100330
Title: Cochlear protection from acoustic injury by inhibitors of p38 mitogen-activated protein kinase and sequestosome 1 stress protein.
Journal: Neuroscience 20100317
Title: p38 regulates pigmentation via proteasomal degradation of tyrosinase.
Journal: The Journal of biological chemistry 20100305
Title: Close association of p38 and JNK with plasminogen-dependent upregulation of PAI-1 in rat astrocytes in vitro.
Journal: Neuroscience letters 20100303
Title: Zinc supplementation partially prevents renal pathological changes in diabetic rats.
Journal: The Journal of nutritional biochemistry 20100301
Title: Influence of NFkappaB inhibitors on IL-1beta-induced chemokine CXCL8 and -10 expression levels in intestinal epithelial cell lines: glucocorticoid ineffectiveness and paradoxical effect of PDTC.
Journal: International journal of colorectal disease 20100301
Title: The ceramide-1-phosphate analogue PCERA-1 modulates tumour necrosis factor-alpha and interleukin-10 production in macrophages via the cAMP-PKA-CREB pathway in a GTP-dependent manner.
Journal: Immunology 20100301
Title: Peripheral origin of IL-1beta production in the rodent hippocampus under in vivo systemic bacterial lipopolysaccharide (LPS) challenge and its regulation by P2X(7) receptors.
Journal: Journal of neuroimmunology 20100226
Title: Pyridinylquinoxalines and pyridinylpyridopyrazines as lead compounds for novel p38 alpha mitogen-activated protein kinase inhibitors.
Journal: Journal of medicinal chemistry 20100211
Title: FGF2-activated ERK mitogen-activated protein kinase enhances Runx2 acetylation and stabilization.
Journal: The Journal of biological chemistry 20100205
Title: Adipocyte-mononuclear cell interaction, Toll-like receptor 4 activation, and high glucose synergistically up-regulate osteopontin expression via an interleukin 6-mediated mechanism.
Journal: The Journal of biological chemistry 20100205
Title: Lycopene suppresses LPS-induced NO and IL-6 production by inhibiting the activation of ERK, p38MAPK, and NF-kappaB in macrophages.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20100201
Title: Cadmium effects on p38/MAPK isoforms in MDA-MB231 breast cancer cells.
Journal: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20100201
Title: Rotenone induces apoptosis in MCF-7 human breast cancer cell-mediated ROS through JNK and p38 signaling.
Journal: Molecular carcinogenesis 20100201
Title: Induction of FGF-2 synthesis by IL-1beta in aqueous humor through P13-kinase and p38 in rabbit corneal endothelium.
Journal: Investigative ophthalmology & visual science 20100201
Title: Cholera toxin-sensitive GTP-binding protein-coupled activation of augmenter of liver regeneration (ALR) receptor and its function in rat kupffer cells.
Journal: Journal of cellular physiology 20100201
Title: Regulation of adenosine receptors expression in rat B lymphocytes by insulin.
Journal: Journal of cellular biochemistry 20100201
Title: Signaling in TRPV1-induced platelet activating factor (PAF) in human esophageal epithelial cells.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20100201
Title: Regulation of matrix metalloproteinase-9 gene expression in MPP+- or 6-OHDA-treated human neuroblastoma SK-N-BE(2)C cells.
Journal: Neurochemistry international 20100201
Title: A chemical genetic approach reveals that p38alpha MAPK activation by diphosphorylation aggravates myocardial infarction and is prevented by the direct binding of SB203580.
Journal: The Journal of biological chemistry 20100129
Title: 4-Hydroxynonenal enhances MMP-9 production in murine macrophages via 5-lipoxygenase-mediated activation of ERK and p38 MAPK.
Journal: Toxicology and applied pharmacology 20100115
Title: Inhibition of endogenous SPARC enhances pancreatic cancer cell growth: modulation by FGFR1-III isoform expression.
Journal: British journal of cancer 20100105
Title: Protective effect of sauchinone by upregulating heme oxygenase-1 via the P38 MAPK and Nrf2/ARE pathways in HepG2 cells.
Journal: Planta medica 20100101
Title: Oxidation of cell surface thiol groups by contact sensitizers triggers the maturation of dendritic cells.
Journal: The Journal of investigative dermatology 20100101
Title: TLR3 in human eosinophils: functional effects and decreased expression during allergic rhinitis.
Journal: International archives of allergy and immunology 20100101
Title: Modulation of cytokine expression in human myeloid dendritic cells by environmental endocrine-disrupting chemicals involves epigenetic regulation.
Journal: Environmental health perspectives 20100101
Title: Sulfur mustard induced cytokine production and cell death: investigating the potential roles of the p38, p53, and NF-kappaB signaling pathways with RNA interference.
Journal: Journal of biochemical and molecular toxicology 20100101
Title: Trisubstituted purines are useful tools for developing potent plant mitogen-activated protein kinase inhibitors.
Journal: Bioscience, biotechnology, and biochemistry 20100101
Title: Sanguinarine as a potent and specific inhibitor of protein phosphatase 2C in vitro and induces apoptosis via phosphorylation of p38 in HL60 cells.
Journal: Bioscience, biotechnology, and biochemistry 20100101
Title: Type I interferon (IFN-alpha/beta) rescues B-lymphocytes from apoptosis via PI3Kdelta/Akt, Rho-A, NFkappaB and Bcl-2/Bcl(XL).
Journal: Cellular immunology 20100101
Title: ATP depletion-induced actin rearrangement reduces cell adhesion via p38 MAPK-HSP27 signaling in renal proximal tubule cells.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101
Title: VEGF secretion by neuroendocrine tumor cells is inhibited by octreotide and by inhibitors of the PI3K/AKT/mTOR pathway.
Journal: Neuroendocrinology 20100101
Title: p38 Mitogen-activated protein kinase is involved in endoplasmic reticulum stress-induced cell death and autophagy in human gingival fibroblasts.
Journal: Biological & pharmaceutical bulletin 20100101
Title: Inhibitory effect of vitamin K(2) on interleukin-1beta-stimulated proliferation of human osteoblasts.
Journal: Biological & pharmaceutical bulletin 20100101
Title: Inhibition of tumor progression locus 2 protein kinase decreases lipopolysaccharide-induced tumor necrosis factor alpha production due to the inhibition of the tip-associated protein induction in RAW264.7 cells.
Journal: Biological & pharmaceutical bulletin 20100101
Title: Resveratrol differentially modulates inflammatory responses of microglia and astrocytes.
Journal: Journal of neuroinflammation 20100101
Title: Growth/differentiation factor-5 induces osteogenic differentiation of human ligamentum flavum cells through activation of ERK1/2 and p38 MAPK.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101
Title: Curcumin protects intestinal mucosal barrier function of rat enteritis via activation of MKP-1 and attenuation of p38 and NF-κB activation.
Journal: PloS one 20100101
Title: Upregulation of cyclooxygenase-2 by 4-nonylphenol is mediated through the cyclic amp response element activation pathway.
Journal: Journal of toxicology and environmental health. Part A 20100101
Title: DMF inhibits PDGF-BB induced airway smooth muscle cell proliferation through induction of heme-oxygenase-1.
Journal: Respiratory research 20100101
Title: Induction of glucose metabolism in stimulated T lymphocytes is regulated by mitogen-activated protein kinase signaling.
Journal: PloS one 20100101
Title: Investigation of the eIF2alpha phosphorylation mechanism in response to proteasome inhibition in melanoma and breast cancer cells.
Journal: Molekuliarnaia biologiia 20100101
Title: Defining the antigen receptor-dependent regulatory network that induces arrest of cycling immature B-lymphocytes.
Journal: BMC systems biology 20100101
Title: Tanshinone IIA inhibits miR-1 expression through p38 MAPK signal pathway in post-infarction rat cardiomyocytes.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101
Title: Ligand-independent activation of the androgen receptor by insulin-like growth factor-I and the role of the MAPK pathway in skeletal muscle cells.
Journal: Molecules and cells 20091231
Title: Role of the nuclear receptors HNF4 alpha, PPAR alpha, and LXRs in the TNF alpha-mediated inhibition of human apolipoprotein A-I gene expression in HepG2 cells.
Journal: Biochemistry 20091222
Title: Irreversibly glycated LDL induce oxidative and inflammatory state in human endothelial cells; added effect of high glucose.
Journal: Biochemical and biophysical research communications 20091218
Title: 3,4-Diaryl-isoxazoles and -imidazoles as potent dual inhibitors of p38alpha mitogen activated protein kinase and casein kinase 1delta.
Journal: Journal of medicinal chemistry 20091210
Title: Repeated preconditioning with hyperbaric oxygen induces neuroprotection against forebrain ischemia via suppression of p38 mitogen activated protein kinase.
Journal: Brain research 20091208
Title: Green tea polyphenols down-regulate caveolin-1 expression via ERK1/2 and p38MAPK in endothelial cells.
Journal: The Journal of nutritional biochemistry 20091201
Title: Effects of chromium picolinate on glucose uptake in insulin-resistant 3T3-L1 adipocytes involve activation of p38 MAPK.
Journal: The Journal of nutritional biochemistry 20091201
Title: Regulation of Lhb and Egr1 gene expression by GNRH pulses in rat pituitaries is both c-Jun N-terminal kinase (JNK)- and extracellular signal-regulated kinase (ERK)-dependent.
Journal: Biology of reproduction 20091201
Title: p38 MAPK mediated in compressive stress-induced chondrogenesis of rat bone marrow MSCs in 3D alginate scaffolds.
Journal: Journal of cellular physiology 20091201
Title: Cyclosporin A sensitises Bcr-Abl positive cells to imatinib mesylate independently of P-glycoprotein expression.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20091201
Title: Doxorubicin induces senescence or apoptosis in rat neonatal cardiomyocytes by regulating the expression levels of the telomere binding factors 1 and 2.
Journal: American journal of physiology. Heart and circulatory physiology 20091201
Title: Dual effect of the novel peptide antagonist K-14585 on proteinase-activated receptor-2-mediated signalling.
Journal: British journal of pharmacology 20091201
Title: Oral malodorous compound inhibits osteoblast proliferation.
Journal: Journal of periodontology 20091201
Title: Procaspase 8 and Bax are up-regulated by distinct pathways in Streptococcal pyrogenic exotoxin B-induced apoptosis.
Journal: The Journal of biological chemistry 20091127
Title: Reactive oxygen species-mediated kinase activation by dihydrotanshinone in tanshinones-induced apoptosis in HepG2 cells.
Journal: Cancer letters 20091118
Title: Enterobacter sakazakii targets DC-SIGN to induce immunosuppressive responses in dendritic cells by modulating MAPKs.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20091115
Title: HMGB1 enhances the proinflammatory activity of lipopolysaccharide by promoting the phosphorylation of MAPK p38 through receptor for advanced glycation end products.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20091115
Title: The nuclear appearance of ERK1/2 and p38 determines the sequential induction of ATF2-Thr71 and ATF2-Thr69 phosphorylation by serum in JNK-deficient cells.
Journal: Molecular and cellular endocrinology 20091113
Title: Heat stress upregulates chaperone heat shock protein 70 and antioxidant manganese superoxide dismutase through reactive oxygen species (ROS), p38MAPK, and Akt.
Journal: Cell stress & chaperones 20091101
Title: Methamphetamine induces heme oxygenase-1 expression in cortical neurons and glia to prevent its toxicity.
Journal: Toxicology and applied pharmacology 20091101
Title: Mitogen-activated protein kinase p38alpha and retinal ischemic preconditioning.
Journal: Experimental eye research 20091101
Title: Inhibition of the JNK signalling pathway enhances proteasome inhibitor-induced apoptosis of kidney cancer cells by suppression of BAG3 expression.
Journal: British journal of pharmacology 20091101
Title: Alpha-defensins increase lung fibroblast proliferation and collagen synthesis via the beta-catenin signaling pathway.
Journal: The FEBS journal 20091101
Title: Trientine, a copper-chelating agent, induced apoptosis in murine fibrosarcoma cells by activation of the p38 MAPK pathway.
Journal: The Journal of veterinary medical science 20091101
Title: Astaxanthin inhibits H2O2-mediated apoptotic cell death in mouse neural progenitor cells via modulation of P38 and MEK signaling pathways.
Journal: Journal of microbiology and biotechnology 20091101
Title: p38 inhibitor intensified cell death in antimycin A-treated As4.1 juxtaglomerular cells via the enhancement of GSH depletion.
Journal: Anticancer research 20091101
Title: Mechanisms underlying modulation of monocarboxylate transporter 1 (MCT1) by somatostatin in human intestinal epithelial cells.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20091101
Title: Regulation of resistin by cyclic mechanical stretch in cultured rat vascular smooth muscle cells.
Journal: Clinical science (London, England : 1979) 20091026
Title: Transcriptional upregulation of mitochondrial uncoupling protein 2 protects against oxidative stress-associated neurogenic hypertension.
Journal: Circulation research 20091023
Title: Inhibition of p38-MAPK potentiates cisplatin-induced apoptosis via GSH depletion and increases intracellular drug accumulation in growth-arrested kidney tubular epithelial cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20091001
Title: Effects of prostaglandin D2 on Na-dependent phosphate transport activity and its intracellular signaling mechanism in osteoblast-like cells.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20091001
Title: Taurine prevents arsenic-induced cardiac oxidative stress and apoptotic damage: role of NF-kappa B, p38 and JNK MAPK pathway.
Journal: Toxicology and applied pharmacology 20091001
Title: Glucosamine inhibits IL-1beta-mediated IL-8 production in prostate cancer cells by MAPK attenuation.
Journal: Journal of cellular biochemistry 20091001
Title: Antioxidant effect of estrogen on bovine aortic endothelial cells.
Journal: The Journal of steroid biochemistry and molecular biology 20091001
Title: Serine 209 resides within a putative p38(MAPK) consensus motif and regulates monoamine oxidase-A activity.
Journal: Journal of neurochemistry 20091001
Title: Differential down-regulation of COX-2 and MMP-13 in human skin fibroblasts by glucosamine-hydrochloride.
Journal: Journal of dermatological science 20091001
Title: Atorvastatin attenuates homocysteine-induced apoptosis in human umbilical vein endothelial cells via inhibiting NADPH oxidase-related oxidative stress-triggered p38MAPK signaling.
Journal: Acta pharmacologica Sinica 20091001
Title: Activation of p38 mitogen-activated protein kinase is required for in vivo brain-derived neurotrophic factor production in the rat hippocampus.
Journal: Neuroscience 20090929
Title: Prevention of Clostridium sordellii lethal toxin-induced apoptotic cell death by tauroursodeoxycholic acid.
Journal: Biochemistry 20090929
Title: Phosphorylation of histone H3 by protein kinase C signaling plays a critical role in the regulation of the developmentally important TBX2 gene.
Journal: The Journal of biological chemistry 20090925
Title: Inhibition of NF-kappaB-dependent transcription by MKP-1: transcriptional repression by glucocorticoids occurring via p38 MAPK.
Journal: The Journal of biological chemistry 20090925
Title: Vitamin D3 induces autophagy in human monocytes/macrophages via cathelicidin.
Journal: Cell host & microbe 20090917
Title: Interferon-gamma priming is involved in the activation of arginase by oligodeoxinucleotides containing CpG motifs in murine macrophages.
Journal: Immunology 20090901
Title: Quercetin inhibits IL-1 beta-induced ICAM-1 expression in pulmonary epithelial cell line A549 through the MAPK pathways.
Journal: Molecular biology reports 20090901
Title: Long-term regulation of vacuolar H(+)-ATPase by angiotensin II in proximal tubule cells.
Journal: Pflugers Archiv : European journal of physiology 20090901
Title: Arecoline-stimulated connective tissue growth factor production in human buccal mucosal fibroblasts: Modulation by curcumin.
Journal: Oral oncology 20090901
Title: Nerve growth factor enhances cough and airway obstruction via TrkA receptor- and TRPV1-dependent mechanisms.
Journal: Thorax 20090901
Title: The p38 mitogen-activated protein kinase regulates 11beta-hydroxysteroid dehydrogenase type 2 (11beta-HSD2) expression in human trophoblast cells through modulation of 11beta-HSD2 messenger ribonucleic acid stability.
Journal: Endocrinology 20090901
Title: p38 MAP kinase inhibits neutrophil development through phosphorylation of C/EBPalpha on serine 21.
Journal: Stem cells (Dayton, Ohio) 20090901
Title: Scratch wound closure of C2C12 mouse myoblasts is enhanced by human platelet lysate.
Journal: Cell biology international 20090901
Title: Biphasic effect of cadmium on cell proliferation in human embryo lung fibroblast cells and its molecular mechanism.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20090901
Title: (-)-Epigallocatechin gallate downregulates EGF receptor via phosphorylation at Ser1046/1047 by p38 MAPK in colon cancer cells.
Journal: Carcinogenesis 20090901
Title: p38 MAPK and MMP-9 cooperatively regulate mucus overproduction in mice exposed to acrolein fog.
Journal: International immunopharmacology 20090901
Title: Antithrombin III suppresses ADP-induced platelet granule secretion: inhibition of HSP27 phosphorylation.
Journal: Archives of biochemistry and biophysics 20090901
Title: p38 MAP kinase inhibitor prevents diastolic dysfunction in rats following HIV gp120 injection in vivo.
Journal: Cardiovascular toxicology 20090901
Title: Spinal microglial expression and mechanical hypersensitivity in a postoperative pain model: comparison with a neuropathic pain model.
Journal: Anesthesiology 20090901
Title: Roles of phosphatidylinositol 3-kinase and p38 mitogen-activated protein kinase in the regulation of protein kinase C-alpha activation in interferon-gamma-stimulated macrophages.
Journal: Immunology 20090901
Title: [Pathogenetic role of tissue factor in endothelial-injury in graft-versus-host disease].
Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20090901
Title: [Effect of signal transduction inhibitors on human endometrial carcinoma cells with differential PTEN gene expression].
Journal: Zhonghua fu chan ke za zhi 20090901
Title: Tetrahydropyridine derivatives with inhibitory activity on the production of proinflammatory cytokines: part 1.
Journal: Bioorganic & medicinal chemistry letters 20090815
Title: Fluoride-induced cyclooxygenase-2 expression and prostaglandin E2 production in A549 human pulmonary epithelial cells.
Journal: Toxicology letters 20090810
Title: Oleoylethanolamide, a natural ligand for PPAR-alpha, inhibits insulin receptor signalling in HTC rat hepatoma cells.
Journal: Biochimica et biophysica acta 20090801
Title: Prolactin induces chitotriosidase expression in human macrophages through PTK, PI3-K, and MAPK pathways.
Journal: Journal of cellular biochemistry 20090801
Title: Regulation of tristetraprolin expression by interleukin-1 beta and dexamethasone in human pulmonary epithelial cells: roles for nuclear factor-kappa B and p38 mitogen-activated protein kinase.
Journal: The Journal of pharmacology and experimental therapeutics 20090801
Title: Effects of hyaluronan oligosaccharide on the expression of MMP-1 in periodontal ligament cells.
Journal: Archives of oral biology 20090801
Title: Leptin and leptin receptor expression in asthma.
Journal: The Journal of allergy and clinical immunology 20090801
Title: Ectopic expression of C/EBPalpha and ID1 is sufficient to restore defective neutrophil development in low-risk myelodysplasia.
Journal: Haematologica 20090801
Title: Differential inhibition of single and cluster type tumor cell migration.
Journal: Anticancer research 20090801
Title: Genistein inhibits cell growth by modulating various mitogen-activated protein kinases and AKT in cervical cancer cells.
Journal: Annals of the New York Academy of Sciences 20090801
Title: Genistein enhances TRAIL-induced apoptosis through inhibition of p38 MAPK signaling in human hepatocellular carcinoma Hep3B cells.
Journal: Chemico-biological interactions 20090715
Title: The up-regulation of monocyte chemoattractant protein-1 (MCP-1) in Ea.hy 926 endothelial cells under long-term low folate stress is mediated by the p38 MAPK pathway.
Journal: Atherosclerosis 20090701
Title: Endogenous IGFBP-3 is required for both growth factor-stimulated cell proliferation and cytokine-induced apoptosis in mammary epithelial cells.
Journal: Journal of cellular physiology 20090701
Title: Upregulation of proinflammatory cytokines and NO production in BV-activated avian macrophage-like cell line (HD11) requires MAPK and NF-kappaB pathways.
Journal: International immunopharmacology 20090701
Title: Peroxiredoxin I contributes to TRAIL resistance through suppression of redox-sensitive caspase activation in human hepatoma cells.
Journal: Carcinogenesis 20090701
Title: Hindlimb unweighting induces changes in the p38MAPK contractile pathway of the rat abdominal aorta.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20090701
Title: Receptor-mediated vascular smooth muscle migration induced by LPA involves p38 mitogen-activated protein kinase pathway activation.
Journal: International journal of molecular sciences 20090701
Title: Dipyridamole inhibits cobalt chloride-induced osteopontin expression in NRK52E cells.
Journal: European journal of pharmacology 20090624
Title: Effects of polychlorinated biphenyls on the neutrophil NADPH oxidase system.
Journal: Toxicology letters 20090622
Title: NADPH oxidase and ERK1/2 are involved in cadmium induced-STAT3 activation in HepG2 cells.
Journal: Toxicology letters 20090622
Title: Endotoxin-induced activation of equine digital vein endothelial cells: role of p38 MAPK.
Journal: Veterinary immunology and immunopathology 20090615
Title: Quercetin-induced apoptotic cascade in cancer cells: antioxidant versus estrogen receptor alpha-dependent mechanisms.
Journal: Molecular nutrition & food research 20090601
Title: Amitriptyline suppresses neuroinflammation-dependent interleukin-10-p38 mitogen-activated protein kinase-heme oxygenase-1 signaling pathway in chronic morphine-infused rats.
Journal: Anesthesiology 20090601
Title: Acetaminophen and lipopolysaccharide act in synergy for the production of pro-inflammatory cytokines in murine RAW264.7 macrophages.
Journal: Journal of immunotoxicology 20090601
Title: [Study of the relationship between early growth response gene 1 activity in p38 mitogen-activated protein kinase pathway and epirubicin resistance of human breast carcinoma cells].
Journal: Zhonghua bing li xue za zhi = Chinese journal of pathology 20090601
Title: PHR regulates growth cone pausing at intermediate targets through microtubule disassembly.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090520
Title: Up-regulation of endothelial monocyte chemoattractant protein-1 by coplanar PCB77 is caveolin-1-dependent.
Journal: Toxicology and applied pharmacology 20090515
Title: High concentrations of ascorbic acid induces apoptosis of human gastric cancer cell by p38-MAP kinase-dependent up-regulation of transferrin receptor.
Journal: Cancer letters 20090508
Title: Antinociception by neutrophil-derived opioid peptides in noninflamed tissue--role of hypertonicity and the perineurium.
Journal: Brain, behavior, and immunity 20090501
Title: Telmisartan, an angiotensin II type 1 receptor antagonist, attenuates T-type Ca2+ channel expression in neonatal rat cardiomyocytes.
Journal: European journal of pharmacology 20090501
Title: Icariin enhances neuronal survival after oxygen and glucose deprivation by increasing SIRT1.
Journal: European journal of pharmacology 20090501
Title: 17beta-Estradiol-induced enhancement of estrogen receptor biosynthesis via MAPK pathway in mouse skeletal muscle myoblasts.
Journal: The journal of physiological sciences : JPS 20090501
Title: [The mechanism of calcium signal regulate preadipocyte differentiation and lipid accumulation in mice].
Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20090501
Title: Treatment with a p38 MAPK inhibitor attenuates cisplatin nephrotoxicity starting after the beginning of renal damage.
Journal: Life sciences 20090424
Title: Role of the hydrogen bonding heteroatom-Lys53 interaction between the p38alpha mitogen-activated protein (MAP) kinase and pyridinyl-substituted 5-membered heterocyclic ring inhibitors.
Journal: Journal of medicinal chemistry 20090423
Title: Activation of endothelial cells after exposure to ambient ultrafine particles: the role of NADPH oxidase.
Journal: Toxicology and applied pharmacology 20090415
Title: Ultra-low dose naloxone restores the antinociceptive effect of morphine in pertussis toxin-treated rats and prevents glutamate transporter downregulation by suppressing the p38 mitogen-activated protein kinase signaling pathway.
Journal: Neuroscience 20090410
Title: CTGF is increased in basal deposits and regulates matrix production through the ERK (p42/p44mapk) MAPK and the p38 MAPK signaling pathways.
Journal: Investigative ophthalmology & visual science 20090401
Title: Mouse model of testosterone-induced muscle fiber hypertrophy: involvement of p38 mitogen-activated protein kinase-mediated Notch signaling.
Journal: The Journal of endocrinology 20090401
Title: Tumour necrosis factor alpha stimulates the production of monocyte chemoattractants by extravillous trophoblast cells via differential activation of MAPK pathways.
Journal: Placenta 20090401
Title: p38 MAP kinase inhibitor reverses stress-induced myocardial dysfunction in vivo.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20090401
Title: Role of spinal microglia in visceral hyperalgesia and NK1R up-regulation in a rat model of chronic stress.
Journal: Gastroenterology 20090401
Title: Trans-Zeatin inhibits UVB-induced matrix metalloproteinase-1 expression via MAP kinase signaling in human skin fibroblasts.
Journal: International journal of molecular medicine 20090401
Title: Modification of cell-surface thiols elicits activation of human monocytic cell line THP-1: possible involvement in effect of haptens 2,4-dinitrochlorobenzene and nickel sulfate.
Journal: The Journal of toxicological sciences 20090401
Title: Intracellular glutathione regulates sesquiterpene lactone-induced conversion of autophagy to apoptosis in human leukemia HL60 cells.
Journal: Anticancer research 20090401
Title: Reactive oxygen species regulate the generation of urokinase plasminogen activator in human hepatoma cells via MAPK pathways after treatment with hepatocyte growth factor.
Journal: Experimental & molecular medicine 20090331
Title: Non-specific in vivo inhibition of CK1 by the pyridinyl imidazole p38 inhibitors SB 203580 and SB 202190.
Journal: BMB reports 20090331
Title: Epithelial cell survival by activating transcription factor 3 (ATF3) in response to chemical ribosome-inactivating stress.
Journal: Biochemical pharmacology 20090315
Title: Spinal p38 mitogen-activated protein kinase mediates allodynia induced by first-degree burn in the rat.
Journal: Journal of neuroscience research 20090301
Title: Oxygen-glucose deprivation activates 5-lipoxygenase mediated by oxidative stress through the p38 mitogen-activated protein kinase pathway in PC12 cells.
Journal: Journal of neuroscience research 20090301
Title: Enhancement of PPAR-beta activity by repetitive low-grade H(2)O(2) stress protects human umbilical vein endothelial cells from subsequent oxidative stress-induced apoptosis.
Journal: Free radical biology & medicine 20090301
Title: Metallic haptens induce differential phenotype of human dendritic cells through activation of mitogen-activated protein kinase and NF-kappaB pathways.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20090301
Title: Flavonol-rich RVHxR from Rhus verniciflua Stokes and its major compound fisetin inhibits inflammation-related cytokines and angiogenic factor in rheumatoid arthritic fibroblast-like synovial cells and in vivo models.
Journal: International immunopharmacology 20090301
Title: 4-Hydroxynonenal enhances CD36 expression on murine macrophages via p38 MAPK-mediated activation of 5-lipoxygenase.
Journal: Free radical biology & medicine 20090301
Title: Regulation of endothelin-1-induced interleukin-6 production by Ca2+ influx in human airway smooth muscle cells.
Journal: European journal of pharmacology 20090301
Title: TNF-alpha reduces the level of Staphylococcus epidermidis internalization by bovine endothelial cells.
Journal: FEMS microbiology letters 20090301
Title: Role of MAPKs in platinum-induced neuronal apoptosis.
Journal: Neurotoxicology 20090301
Title: Inflammation in methotrexate-induced pulmonary toxicity occurs via the p38 MAPK pathway.
Journal: Toxicology 20090227
Title: Docosahexaenoic acid induces apoptosis in colorectal carcinoma cells by modulating the PI3 kinase and p38 MAPK pathways.
Journal: The Journal of nutritional biochemistry 20090201
Title: Cell growth of ovarian cancer cells is stimulated by xenoestrogens through an estrogen-dependent pathway, but their stimulation of cell growth appears not to be involved in the activation of the mitogen-activated protein kinases ERK-1 and p38.
Journal: The Journal of reproduction and development 20090201
Title: ERK MAPK activation mediates the antiapoptotic signaling of melatonin in UVB-stressed U937 cells.
Journal: Free radical biology & medicine 20090201
Title: Differential roles of MAPKs and MSK1 signalling pathways in the regulation of c-Jun during phenylephrine-induced cardiac myocyte hypertrophy.
Journal: Molecular and cellular biochemistry 20090201
Title: Effect of curcumin on acidic pH-induced expression of IL-6 and IL-8 in human esophageal epithelial cells (HET-1A): role of PKC, MAPKs, and NF-kappaB.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20090201
Title: Induction of COX-2 in human airway cells by manganese: role of PI3K/PKB, p38 MAPK, PKCs, Src, and glutathione depletion.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20090201
Title: Machilin A isolated from Myristica fragrans stimulates osteoblast differentiation.
Journal: Planta medica 20090201
Title: LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection.
Journal: American journal of physiology. Heart and circulatory physiology 20090201
Title: C-reactive protein modulates human lung fibroblast migration.
Journal: Experimental lung research 20090201
Title: Possible involvement of caspase-6 and -7 but not caspase-3 in the regulation of hypoxia-induced apoptosis in tube-forming endothelial cells.
Journal: Experimental cell research 20090115
Title: Phosphorylation of serine 271 on 5-lipoxygenase and its role in nuclear export.
Journal: The Journal of biological chemistry 20090102
Title: 7-Ketocholesterol upregulates interleukin-6 via mechanisms that are distinct from those of tumor necrosis factor-alpha, in vascular smooth muscle cells.
Journal: Journal of vascular research 20090101
Title: Involvement of AMP-activated protein kinase and p38 mitogen-activated protein kinase in 8-Cl-cAMP-induced growth inhibition.
Journal: Journal of cellular physiology 20090101
Title: Organochlorine-mediated potentiation of the general coactivator p300 through p38 mitogen-activated protein kinase.
Journal: Carcinogenesis 20090101
Title: Enhanced induction of LPS-induced fibroblast MCP-1 by interferon-gamma: involvement of JNK and MAPK phosphatase-1.
Journal: Cellular immunology 20090101
Title: AP-1 and ERK1 but not p38 nor JNK is required for CRPV early protein 2-dependent MMP-9 promoter activation in rabbit epithelial cells.
Journal: Virus research 20090101
Title: Berberine reduces insulin resistance through protein kinase C-dependent up-regulation of insulin receptor expression.
Journal: Metabolism: clinical and experimental 20090101
Title: Arsenic induced apoptosis in malignant melanoma cells is enhanced by menadione through ROS generation, p38 signaling and p53 activation.
Journal: Apoptosis : an international journal on programmed cell death 20090101
Title: Antiproliferative effects of CC-8062 and CC-8075 in pancreatic cancer cells.
Journal: Pancreas 20090101
Title: Neuronal injury induces cytokine-induced neutrophil chemoattractant-1 (CINC-1) production in astrocytes.
Journal: Journal of pharmacological sciences 20090101
Title: p38 MAPK contributes to angiotensin II-induced COX-2 expression in aortic fibroblasts from normotensive and hypertensive rats.
Journal: Journal of hypertension 20090101
Title: Apoptosis induction by oxidized glycated LDL in human retinal capillary pericytes is independent of activation of MAPK signaling pathways.
Journal: Molecular vision 20090101
Title: Urocortin II induces nitric oxide production through cAMP and Ca2+ related pathways in endothelial cells.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20090101
Title: The pivotal role of p38 and NF-kappaB signal pathways in the maturation of human monocyte-derived dendritic cells stimulated by streptococcal agent OK-432.
Journal: Immunobiology 20090101
Title: Upregulation of Toll-like receptor (TLR) expression and release of cytokines from P815 mast cells by GM-CSF.
Journal: BMC cell biology 20090101
Title: Deoxycholate induces COX-2 expression via Erk1/2-, p38-MAPK and AP-1-dependent mechanisms in esophageal cancer cells.
Journal: BMC cancer 20090101
Title: TGF-beta inhibits CYP17 transcription in H295R cells acting via activin receptor-like kinase 5.
Journal: Endocrine research 20090101
Title: Regulation of CREB activation by p38 mitogen activated protein kinase during human primary erythroblast differentiation.
Journal: International journal of immunopathology and pharmacology 20090101
Title: Leptin interferes with 3',5'-cyclic adenosine monophosphate (cAMP) signaling to inhibit steroidogenesis in human granulosa cells.
Journal: Reproductive biology and endocrinology : RB&E 20090101
Title: The proliferation and migration effects of huangqi on RSC96 Schwann cells.
Journal: The American journal of Chinese medicine 20090101
Title: IL-2 regulates SEB induced toxic shock syndrome in BALB/c mice.
Journal: PloS one 20090101
Title: Signaling pathway for TNF-alpha-induced MMP-9 expression: mediation through p38 MAP kinase, and inhibition by anti-cancer molecule magnolol in human urinary bladder cancer 5637 cells.
Journal: International immunopharmacology 20081220
Title: GM1 induces p38 and microtubule dependent ramification of rat primary microglia in vitro.
Journal: Brain research 20081209
Title: Involvement of p38 mitogen-activated protein kinase pathway in honokiol-induced apoptosis in a human hepatoma cell line (hepG2).
Journal: Liver international : official journal of the International Association for the Study of the Liver 20081201
Title: A role for IL-18 in human neutrophil apoptosis.
Journal: Shock (Augusta, Ga.) 20081201
Title: Lipid-soluble smoke particles upregulate vascular smooth muscle ETB receptors via activation of mitogen-activating protein kinases and NF-kappaB pathways.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20081201
Title: The antipsychotic spiperone attenuates inflammatory response in cultured microglia via the reduction of proinflammatory cytokine expression and nitric oxide production.
Journal: Journal of neurochemistry 20081201
Title: Chemical enhancement in embryo development and stem cell derivation from single blastomeres.
Journal: Cloning and stem cells 20081201
Title: Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induce cyclooxygenase-2 activity in human gastric cancer cells: Involvement of nicotinic acetylcholine receptor (nAChR) and beta-adrenergic receptor signaling pathways.
Journal: Toxicology and applied pharmacology 20081201
Title: Phosphorylation of TRPV1 by neurokinin-1 receptor agonist exaggerates the capsaicin-mediated substance P release from cultured rat dorsal root ganglion neurons.
Journal: Neuropharmacology 20081201
Title: o,p'-DDT induces cyclooxygenase-2 gene expression in murine macrophages: Role of AP-1 and CRE promoter elements and PI3-kinase/Akt/MAPK signaling pathways.
Journal: Toxicology and applied pharmacology 20081201
Title: Mechanism of attenuation of muscle protein degradation induced by tumor necrosis factor-alpha and angiotensin II by beta-hydroxy-beta-methylbutyrate.
Journal: American journal of physiology. Endocrinology and metabolism 20081201
Title: AMPK mediates curcumin-induced cell death in CaOV3 ovarian cancer cells.
Journal: Oncology reports 20081201
Title: Modulation of TNF-alpha-induced endothelial cell activation by glucosamine, a naturally occurring amino monosaccharide.
Journal: International journal of molecular medicine 20081201
Title: Effects of p38 MAP kinase inhibitors on the differentiation and maturation of erythroid progenitors.
Journal: Toxicologic pathology 20081201
Title: High glucose conditions induce upregulation of fractalkine and monocyte chemotactic protein-1 in human smooth muscle cells.
Journal: Thrombosis and haemostasis 20081201
Title: Involvement of regulatory elements on corticotropin-releasing factor gene promoter in hypothalamic 4B cells.
Journal: Journal of endocrinological investigation 20081201
Title: The p38 mitogen-activated protein kinase augments nucleotide excision repair by mediating DDB2 degradation and chromatin relaxation.
Journal: The Journal of biological chemistry 20081121
Title: Novel piperidinylpyrimidine derivatives as inhibitors of HIV-1 LTR activation.
Journal: Bioorganic & medicinal chemistry 20081115
Title: Egr-1 mRNA induction by medium flow involves mRNA stabilization and is enhanced by the p38 inhibitor SB203580 in osteoblast-like cells.
Journal: Acta physiologica (Oxford, England) 20081101
Title: Initiation of caspase-independent death in mouse mesangial cells by Cd2+: involvement of p38 kinase and CaMK-II.
Journal: Journal of cellular physiology 20081101
Title: Chemically defined medium supporting cardiomyocyte differentiation of human embryonic stem cells.
Journal: Differentiation; research in biological diversity 20081101
Title: Curcumin inhibits VEGF-mediated angiogenesis in human intestinal microvascular endothelial cells through COX-2 and MAPK inhibition.
Journal: Gut 20081101
Title: 15-deoxy-delta 12,14-prostaglandin J(2) inhibits the synthesis of the acute phase protein SIP24 in cartilage: Involvement of COX-2 in resolution of inflammation.
Journal: Journal of cellular physiology 20081101
Title: Identification of regions of the P2X(7) receptor that contribute to human and rat species differences in antagonist effects.
Journal: British journal of pharmacology 20081101
Title: High-fat diet-induced obesity leads to resistance to leptin-induced cardiomyocyte contractile response.
Journal: Obesity (Silver Spring, Md.) 20081101
Title: Involvement of the PI3K/Akt pathway in estrogen-mediated regulation of human CYP7B1: identification of CYP7B1 as a novel target for PI3K/Akt and MAPK signalling.
Journal: The Journal of steroid biochemistry and molecular biology 20081101
Title: Bile acids induce CCN2 production through p38 MAP kinase activation in human bronchial epithelial cells: a factor contributing to airway fibrosis.
Journal: Respirology (Carlton, Vic.) 20081101
Title: Induction of high mobility group box 1 release from serotonin-stimulated human umbilical vein endothelial cells.
Journal: International journal of molecular medicine 20081101
Title: Vitamin C inhibits p53-induced replicative senescence through suppression of ROS production and p38 MAPK activity.
Journal: International journal of molecular medicine 20081101
Title: Cobalt chloride decreases EC-SOD expression through intracellular ROS generation and p38-MAPK pathways in COS7 cells.
Journal: Free radical research 20081101
Title: Antioxidant effects of equol on bovine aortic endothelial cells.
Journal: Biochemical and biophysical research communications 20081024
Title: Hypoxia induces discoidin domain receptor-2 expression via the p38 pathway in vascular smooth muscle cells to increase their migration.
Journal: Biochemical and biophysical research communications 20081003
Title: Mechanism of estrogen-mediated improvement in cardiac function after trauma-hemorrhage: p38-dependent normalization of cardiac Akt phosphorylation and glycogen levels.
Journal: Shock (Augusta, Ga.) 20081001
Title: Role of the p38 mitogen-activated protein kinase/cytosolic phospholipase A2 signaling pathway in blood-brain barrier disruption after focal cerebral ischemia and reperfusion.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20081001
Title: Double-stranded RNA-activated protein kinase mediates induction of interleukin-8 expression by deoxynivalenol, Shiga toxin 1, and ricin in monocytes.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20081001
Title: Keratinocyte-derived vascular endothelial growth factor biosynthesis represents a pleiotropic side effect of peroxisome proliferator-activated receptor-gamma agonist troglitazone but not rosiglitazone and involves activation of p38 mitogen-activated protein kinase: implications for diabetes-impaired skin repair.
Journal: Molecular pharmacology 20081001
Title: TLR4 signaling induces B7-H1 expression through MAPK pathways in bladder cancer cells.
Journal: Cancer investigation 20081001
Title: Ammonia impairs neutrophil phagocytic function in liver disease.
Journal: Hepatology (Baltimore, Md.) 20081001
Title: PP2 regulates human trophoblast cells differentiation by activating p38 and ERK1/2 and inhibiting FAK activation.
Journal: Placenta 20081001
Title: The role of fatty acids and caveolin-1 in tumor necrosis factor alpha-induced endothelial cell activation.
Journal: Metabolism: clinical and experimental 20081001
Title: SB203580, a pharmacological inhibitor of p38 MAP kinase transduction pathway activates ERK and JNK MAP kinases in primary cultures of human hepatocytes.
Journal: European journal of pharmacology 20080928
Title: Resveratrol inhibits EMMPRIN expression via P38 and ERK1/2 pathways in PMA-induced THP-1 cells.
Journal: Biochemical and biophysical research communications 20080926
Title: Role of oxidative stress in the induction of metallothionein-2A and heme oxygenase-1 gene expression by the antineoplastic agent gallium nitrate in human lymphoma cells.
Journal: Free radical biology & medicine 20080915
Title: Bcl2, a transcriptional target of p38alpha, is critical for neuronal commitment of mouse embryonic stem cells.
Journal: Cell death and differentiation 20080901
Title: A p38-p65 transcription complex induced by endothelin-1 mediates signal transduction in cancer cells.
Journal: Biochimica et biophysica acta 20080901
Title: Deoxynivalenol induces p38 interaction with the ribosome in monocytes and macrophages.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080901
Title: p38 and c-Jun N-terminal kinase mitogen-activated protein kinase signaling pathways play distinct roles in the response of organogenesis-stage embryos to a teratogen.
Journal: The Journal of pharmacology and experimental therapeutics 20080901
Title: Molecular basis for the induction of an angiogenesis inhibitor, thrombospondin-1, by 5-fluorouracil.
Journal: Cancer research 20080901
Title: Spinal p38 MAP kinase regulates peripheral cholinergic outflow.
Journal: Arthritis and rheumatism 20080901
Title: ATF-1 is a hypoxia-responsive transcriptional activator of skeletal muscle mitochondrial-uncoupling protein 3.
Journal: The Journal of biological chemistry 20080822
Title: Innate immune responses of epididymal epithelial cells to Staphylococcus aureus infection.
Journal: Immunology letters 20080815
Title: Cadmium specifically induces MKP-1 expression via the glutathione depletion-mediated p38 MAPK activation in C6 glioma cells.
Journal: Neuroscience letters 20080808
Title: Exposure to metal ions regulates mRNA levels of APP and BACE1 in PC12 cells: blockage by curcumin.
Journal: Neuroscience letters 20080808
Title: Synergistic regulation of COX-2 expression by bombesin and transforming growth factor-beta.
Journal: Digestive diseases and sciences 20080801
Title: Role of p38 MAPK and pro-inflammatory cytokines expression in glutamate-induced neuronal death of neonatal rats.
Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20080801
Title: Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies.
Journal: The Biochemical journal 20080801
Title: Characterization of early events involved in human dendritic cell maturation induced by sensitizers: cross talk between MAPK signalling pathways.
Journal: Toxicology and applied pharmacology 20080801
Title: PGE2 inhibits basolateral 50 pS potassium channels in the thick ascending limb of the rat kidney.
Journal: Kidney international 20080801
Title: Transforming growth factor-beta stimulates intestinal epithelial focal adhesion kinase synthesis via Smad- and p38-dependent mechanisms.
Journal: The American journal of pathology 20080801
Title: Combination treatment with arsenic trioxide and sulindac enhances apoptotic cell death in lung cancer cells via activation of oxidative stress and mitogen-activated protein kinases.
Journal: Oncology reports 20080801
Title: Effect of exposure to an extremely low frequency-electromagnetic field on the cellular collagen with respect to signaling pathways in osteoblast-like cells.
Journal: The journal of medical investigation : JMI 20080801
Title: Design, synthesis, and biological evaluation of novel Tri- and tetrasubstituted imidazoles as highly potent and specific ATP-mimetic inhibitors of p38 MAP kinase: focus on optimized interactions with the enzyme's surface-exposed front region.
Journal: Journal of medicinal chemistry 20080724
Title: Vitamin C suppresses proliferation of the human melanoma cell SK-MEL-2 through the inhibition of cyclooxygenase-2 (COX-2) expression and the modulation of insulin-like growth factor II (IGF-II) production.
Journal: Journal of cellular physiology 20080701
Title: Asbestos-induced MKP-3 expression augments TNF-alpha gene expression in human monocytes.
Journal: American journal of respiratory cell and molecular biology 20080701
Title: Hyperosmolarity-induced dilation and epithelial bioelectric responses of guinea pig trachea in vitro: role of kinase signaling.
Journal: The Journal of pharmacology and experimental therapeutics 20080701
Title: Oxidative stress regulates type 3 deiodinase and type 2 deiodinase in cultured rat astrocytes.
Journal: Endocrinology 20080701
Title: Signal transduction and transcriptional control of cardiac connexin43 up-regulation after alpha 1-adrenoceptor stimulation.
Journal: The Journal of pharmacology and experimental therapeutics 20080701
Title: HSP27 phosphorylation is correlated with ADP-induced platelet granule secretion.
Journal: Archives of biochemistry and biophysics 20080701
Title: Neurotoxicity of cadmium on immature hippocampus and a neuroprotective role for p38 MAPK.
Journal: Neurotoxicology 20080701
Title: LPS-induced vascular endothelial growth factor expression in rat lung pericytes.
Journal: Shock (Augusta, Ga.) 20080701
Title: Chk1 inhibition activates p53 through p38 MAPK in tetraploid cancer cells.
Journal: Cell cycle (Georgetown, Tex.) 20080701
Title: Chlorobenzene induces the NF-kappa B and p38 MAP kinase pathways in lung epithelial cells.
Journal: Inhalation toxicology 20080701
Title: Anti-tumor effect of beta-elemene in glioblastoma cells depends on p38 MAPK activation.
Journal: Cancer letters 20080608
Title: Up-regulation of HSP70 by the fibronectin-derived peptide PHSRN in human corneal epithelial cells.
Journal: Biochemical and biophysical research communications 20080606
Title: Heme-oxygenase 1 gene expression is a marker for hexavalent chromium-induced stress and toxicity in human dermal fibroblasts.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080601
Title: Heme oxygenase-1 mediates the anti-inflammatory effect of Curcumin within LPS-stimulated human monocytes.
Journal: Journal of cellular physiology 20080601
Title: p38 MAPK-dependent eNOS upregulation is critical for 17beta-estradiol-mediated cardioprotection following trauma-hemorrhage.
Journal: American journal of physiology. Heart and circulatory physiology 20080601
Title: Octylphenol stimulates resistin gene expression in 3T3-L1 adipocytes via the estrogen receptor and extracellular signal-regulated kinase pathways.
Journal: American journal of physiology. Cell physiology 20080601
Title: p38 kinase/cytosolic phospholipase A2/cyclooxygenase-2 pathway: a new signaling cascade for lipopolysaccharide-induced interleukin-1beta and interleukin-6 release in differentiated U937 cells.
Journal: Prostaglandins & other lipid mediators 20080601
Title: p38 MAP kinase mediates arsenite-induced apoptosis through FOXO3a activation and induction of Bim transcription.
Journal: Apoptosis : an international journal on programmed cell death 20080601
Title: Kinase activity, heat shock protein 27 phosphorylation, and lung epithelial cell glutathione.
Journal: Experimental lung research 20080601
Title: Role of endothelin receptors on basal and endothelin-1-stimulated lung myofibroblast proliferation.
Journal: Canadian journal of physiology and pharmacology 20080601
Title: Differential contribution of spinal mitogen-activated protein kinases to the phase of long-lasting allodynia evoked by intrathecal administration of ATP in rats.
Journal: Biological & pharmaceutical bulletin 20080601
Title: Inhibition of ERK and activation of p38 are involved in diallyl disulfide induced apoptosis of leukemia HL-60 cells.
Journal: Archives of pharmacal research 20080601
Title: Pharmacological inhibitors of JNK and ERK kinases SP600125 and U0126 are not appropriate tools for studies of drug metabolism because they activate aryl hydrocarbon receptor.
Journal: General physiology and biophysics 20080601
Title: Involvement of NF-kappaB and AP-1 activation in icariin promoted cardiac differentiation of mouse embryonic stem cells.
Journal: European journal of pharmacology 20080531
Title: The role of RIP2 in p38 MAPK activation in the stressed heart.
Journal: The Journal of biological chemistry 20080502
Title: Inhibition of jet fuel aliphatic hydrocarbon induced toxicity in human epidermal keratinocytes.
Journal: Journal of applied toxicology : JAT 20080501
Title: In vitro, inhibition of mitogen-activated protein kinase pathways protects against bupivacaine- and ropivacaine-induced neurotoxicity.
Journal: Anesthesia and analgesia 20080501
Title: Inorganic arsenic activates reduced NADPH oxidase in human primary macrophages through a Rho kinase/p38 kinase pathway.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20080501
Title: Isoxazolone based inhibitors of p38 MAP kinases.
Journal: Journal of medicinal chemistry 20080424
Title: Involvement of oxidative stress-activated JNK signaling in the methamphetamine-induced cell death of human SH-SY5Y cells.
Journal: Toxicology 20080418
Title: p38 MAPK, but not ERK1/2, is critically involved in the cytotoxicity of the novel vascular disrupting agent combretastatin A4.
Journal: International journal of cancer 20080415
Title: Involvement of mitogen-activated protein kinases and NFkappaB in LPS-induced CD40 expression on human monocytic cells.
Journal: Toxicology and applied pharmacology 20080415
Title: Low intensity pulsed ultrasound accelerates macrophage phagocytosis by a pathway that requires actin polymerization, Rho, and Src/MAPKs activity.
Journal: Cellular signalling 20080401
Title: Activation of c-Jun N-terminal kinase (JNK) by widely used specific p38 MAPK inhibitors SB202190 and SB203580: a MLK-3-MKK7-dependent mechanism.
Journal: Cellular signalling 20080401
Title: Both direct and indirect effects account for the pro-inflammatory activity of enteropathogenic mycotoxins on the human intestinal epithelium: stimulation of interleukin-8 secretion, potentiation of interleukin-1beta effect and increase in the transepithelial passage of commensal bacteria.
Journal: Toxicology and applied pharmacology 20080401
Title: Short-period hypoxia increases mouse embryonic stem cell proliferation through cooperation of arachidonic acid and PI3K/Akt signalling pathways.
Journal: Cell proliferation 20080401
Title: Anti-fas activating antibody enhances trophoblast outgrowth on endometrial epithelial cells by induction of P38 MAPK/JNK-mediated apoptosis.
Journal: Placenta 20080401
Title: Pharmacophore identification of Raf-1 kinase inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20080401
Title: Induction of apoptosis by a stilbene analog involves Bax translocation regulated by p38 MAPK and Akt.
Journal: Archives of pharmacal research 20080401
Title: Lipopolysaccharide (LPS) of Porphyromonas gingivalis induces IL-1beta, TNF-alpha and IL-6 production by THP-1 cells in a way different from that of Escherichia coli LPS.
Journal: Innate immunity 20080401
Title: Phosphorylation of sodium channel Na(v)1.8 by p38 mitogen-activated protein kinase increases current density in dorsal root ganglion neurons.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080319
Title: The design and synthesis of novel alpha-ketoamide-based p38 MAP kinase inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20080315
Title: Inhibition of p38 MAP kinase improves survival of cardiac myocytes with hypoxia and burn serum challenge.
Journal: Burns : journal of the International Society for Burn Injuries 20080301
Title: TLR4 signaling induces functional nerve growth factor receptor p75NTR on mouse dendritic cells via p38MAPK and NF-kappa B pathways.
Journal: Molecular immunology 20080301
Title: The role of redox-sensitive transcription factors NF-kappaB and AP-1 in the modulation of the Cyp1a1 gene by mercury, lead, and copper.
Journal: Free radical biology & medicine 20080301
Title: Plitidepsin has a dual effect inhibiting cell cycle and inducing apoptosis via Rac1/c-Jun NH2-terminal kinase activation in human melanoma cells.
Journal: The Journal of pharmacology and experimental therapeutics 20080301
Title: Cytochrome P4502E1 sensitizes to tumor necrosis factor alpha-induced liver injury through activation of mitogen-activated protein kinases in mice.
Journal: Hepatology (Baltimore, Md.) 20080301
Title: Involvement of protein kinase C beta-extracellular signal-regulating kinase 1/2/p38 mitogen-activated protein kinase-heat shock protein 27 activation in hepatocellular carcinoma cell motility and invasion.
Journal: Cancer science 20080301
Title: Mycoplasma genitalium-derived lipid-associated membrane proteins induce activation of MAPKs, NF-kappaB and AP-1 in THP-1 cells.
Journal: FEMS immunology and medical microbiology 20080301
Title: Role of mitogen-activated protein kinases in the iNOS production and cytokine secretion by Salmonella enterica serovar Typhimurium porins.
Journal: Cytokine 20080301
Title: Inhibition of Src and p38 MAP kinases suppresses the change of claudin expression induced on dedifferentiation of primary cultured parotid acinar cells.
Journal: American journal of physiology. Cell physiology 20080301
Title: Role of p38 MAPK in the selective release of IL-8 induced by chemical allergen in naive THp-1 cells.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20080301
Title: MD-2 controls bacterial lipopolysaccharide hyporesponsiveness in human intestinal epithelial cells.
Journal: Life sciences 20080227
Title: [Calreticulin upregulation induced by hypoxic preconditioning relieves oxidative stress injury in rat cardiomyocytes].
Journal: Sheng li xue bao : [Acta physiologica Sinica] 20080225
Title: Ciglitazone induces caspase-independent apoptosis via p38-dependent AIF nuclear translocation in renal epithelial cells.
Journal: Toxicology 20080203
Title: Toll-like receptor agonists stimulate human neutrophil migration via activation of mitogen-activated protein kinases.
Journal: Immunology 20080201
Title: Role of p38-mitogen-activated protein kinase in ischaemic preconditioning in rat heart.
Journal: Clinical and experimental pharmacology & physiology 20080201
Title: Interleukin-1beta gene in orange-spotted grouper, Epinephelus coioides: molecular cloning, expression, biological activities and signal transduction.
Journal: Molecular immunology 20080201
Title: Effects of the marine toxins okadaic acid and palytoxin on mussel phagocytosis.
Journal: Fish & shellfish immunology 20080201
Title: Internalization of Staphylococcus aureus by bovine endothelial cells is associated with the activity state of NF-kappaB and modulated by the pro-inflammatory cytokines TNF-alpha and IL-1beta.
Journal: Scandinavian journal of immunology 20080201
Title: Carbon monoxide donors or heme oxygenase-1 (HO-1) overexpression blocks interleukin-18-mediated NF-kappaB-PTEN-dependent human cardiac endothelial cell death.
Journal: Free radical biology & medicine 20080201
Title: Xenoestrogens modulate vascular endothelial growth factor secretion in breast cancer cells through an estrogen receptor-dependent mechanism.
Journal: The Journal of endocrinology 20080201
Title: Cyclooxygenase-2 induction by lysophosphatidylcholine in cultured rat vascular smooth muscle cells: involvement of the p38MAPK pathway.
Journal: Biomedical research (Tokyo, Japan) 20080201
Title: Roles of ERK and p38 mitogen-activated protein kinases in phorbol ester-induced NF-kappaB activation and COX-2 expression in human breast epithelial cells.
Journal: Chemico-biological interactions 20080130
Title: Enhancement of bone morphogenetic protein-2 expression and bone formation by coumarin derivatives via p38 and ERK-dependent pathway in osteoblasts.
Journal: European journal of pharmacology 20080128
Title: p38-MAPK is involved in restoration of the lost protection of preconditioning by nicorandil in vivo.
Journal: European journal of pharmacology 20080128
Title: [The role of mitogen-activated protein kinase cascades in inhibition of proliferation in human prostate carcinoma cells by raloxifene: an in vitro experiment].
Journal: Zhonghua yi xue za zhi 20080122
Title: Extracellular calcium-sensing receptor activation induces vitamin D receptor levels in proximal kidney HK-2G cells by a mechanism that requires phosphorylation of p38alpha MAPK.
Journal: The Journal of biological chemistry 20080104
Title: Inhibition of cancer cell invasion by cannabinoids via increased expression of tissue inhibitor of matrix metalloproteinases-1.
Journal: Journal of the National Cancer Institute 20080102
Title: PI3-K/Akt-dependent activation of cAMP-response element-binding (CREB) protein in Jurkat T leukemia cells treated with TRAIL.
Journal: Journal of cellular physiology 20080101
Title: Sequential activation of JAKs, STATs and xanthine dehydrogenase/oxidase by hypoxia in lung microvascular endothelial cells.
Journal: The international journal of biochemistry & cell biology 20080101
Title: Progestin-inflammatory cytokine interactions affect matrix metalloproteinase-1 and -3 expression in term decidual cells: implications for treatment of chorioamnionitis-induced preterm delivery.
Journal: The Journal of clinical endocrinology and metabolism 20080101
Title: Specific inhibition of basal mitogen-activated protein kinases and phosphatidylinositol 3 kinase activities in leukemia cells: a possible therapeutic role for the kinase inhibitors.
Journal: Experimental hematology 20080101
Title: Biphenyl amide p38 kinase inhibitors 1: Discovery and binding mode.
Journal: Bioorganic & medicinal chemistry letters 20080101
Title: Role of p38 in regulation of hematopoiesis: effect of p38 inhibition on cytokine production and transcription factor activity in human bone marrow stromal cells.
Journal: Blood cells, molecules & diseases 20080101
Title: High glucose enhances lipopolysaccharide-stimulated CD14 expression in U937 mononuclear cells by increasing nuclear factor kappaB and AP-1 activities.
Journal: The Journal of endocrinology 20080101
Title: A quantitative analysis of kinase inhibitor selectivity.
Journal: Nature biotechnology 20080101
Title: Opposite effect of phorbol ester PMA on PTGS2 and PGDH mRNA expression in human chorion trophoblast cells.
Journal: Reproductive sciences (Thousand Oaks, Calif.) 20080101
Title: Troglitazone suppresses transforming growth factor beta-mediated fibrogenesis in retinal pigment epithelial cells.
Journal: Molecular vision 20080101
Title: Nitric oxide activated by p38 and NF-kappaB facilitates apoptosis and cell cycle arrest under oxidative stress in evodiamine-treated human melanoma A375-S2 cells.
Journal: Free radical research 20080101
Title: [Effect of p38 MAPK on elemene-induced cell cycle arrest in C6 glioblastoma cells].
Journal: Zhonghua yi xue za zhi 20080101
Title: Cell type-specific activation of the cytomegalovirus promoter by dimethylsulfoxide and 5-aza-2'-deoxycytidine.
Journal: The international journal of biochemistry & cell biology 20080101
Title: Protein kinase C beta overexpression induces fibrotic effects in human proximal tubular epithelial cells.
Journal: The international journal of biochemistry & cell biology 20080101
Title: Differential activation of p38 and extracellular signal-regulated kinase in spinal cord in a model of bee venom-induced inflammation and hyperalgesia.
Journal: Molecular pain 20080101
Title: NF-kappaB and AP-1 are key signaling pathways in the modulation of NAD(P)H:quinone oxidoreductase 1 gene by mercury, lead, and copper.
Journal: Journal of biochemical and molecular toxicology 20080101
Title: Function of Rho-kinase in prostaglandin D2-induced interleukin-6 synthesis in osteoblasts.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20080101
Title: Cellular mechanisms of hepatocyte growth factor-mediated urokinase plasminogen activator secretion by MAPK signaling in hepatocellular carcinoma.
Journal: Tumori 20080101
Title: A role of p38 mitogen-activated protein kinase in adenosine A₁ receptor-mediated synaptic depotentiation in area CA1 of the rat hippocampus.
Journal: Molecular brain 20080101
Title: ICAM-1 and p38 MAPK mediate fibrinogen-induced migration of human vascular smooth muscle cells.
Journal: European journal of pharmacology 20071222
Title: Phorbol 12-myristate 13-acetate-activated protein kinase C increased migratory activity of subconjunctival fibroblasts via stress-activated protein kinase pathways.
Journal: Molecular vision 20071221
Title: A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20071218
Title: The selectivity of protein kinase inhibitors: a further update.
Journal: The Biochemical journal 20071215
Title: Synthesis and in vivo activity of MK2 and MK2 substrate-selective p38alpha(MAPK) inhibitors in Werner syndrome cells.
Journal: Bioorganic & medicinal chemistry letters 20071215
Title: Evaluation of proinflammatory cytokine pathway inhibitors for p38 MAPK inhibitory potential.
Journal: Journal of medicinal chemistry 20071213
Title: p38alpha MAP kinase mediates hypoxia-induced motor neuron cell death: a potential target of minocycline's neuroprotective action.
Journal: Neurochemical research 20071201
Title: Resveratrol enhances proliferation and osteoblastic differentiation in human mesenchymal stem cells via ER-dependent ERK1/2 activation.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20071201
Title: Extrinsic regulation of T-type Ca(2+) channel expression in chick nodose ganglion neurons.
Journal: Developmental neurobiology 20071201
Title: Inhibition of histone deacetylases triggers pharmacologic preconditioning effects against myocardial ischemic injury.
Journal: Cardiovascular research 20071201
Title: VEGF induces Tie2 shedding via a phosphoinositide 3-kinase/Akt dependent pathway to modulate Tie2 signaling.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20071201
Title: p38 and ERK1/2 MAPKs mediate the interplay of TNF-alpha and IL-10 in regulating oxidative stress and cardiac myocyte apoptosis.
Journal: American journal of physiology. Heart and circulatory physiology 20071201
Title: Redox-dependent coronary metabolic dilation.
Journal: American journal of physiology. Heart and circulatory physiology 20071201
Title: QSAR study of Phenoxypyrimidine Derivatives as Potent Inhibitors of p38 Kinase using different chemometric tools.
Journal: Chemical biology & drug design 20071201
Title: Oridonin induced autophagy in human cervical carcinoma HeLa cells through Ras, JNK, and P38 regulation.
Journal: Journal of pharmacological sciences 20071201
Title: Function of oxidative stress in the regulation of hematopoietic stem cell-niche interaction.
Journal: Biochemical and biophysical research communications 20071123
Title: Histone H3 phosphorylation at serine 10 and serine 28 is mediated by p38 MAPK in rat hepatocytes exposed to ethanol and acetaldehyde.
Journal: European journal of pharmacology 20071114
Title: Involvement of ERK signaling in halofuginone-driven inhibition of fibroblast ability to contract collagen lattices.
Journal: European journal of pharmacology 20071114
Title: EGCG-targeted p57/KIP2 reduces tumorigenicity of oral carcinoma cells: role of c-Jun N-terminal kinase.
Journal: Toxicology and applied pharmacology 20071101
Title: Inhibition of ERK and JNK decreases both osmosensitive taurine release and cell proliferation in glioma cells.
Journal: Neurochemical research 20071101
Title: Thimerosal-induced apoptosis in human SCM1 gastric cancer cells: activation of p38 MAP kinase and caspase-3 pathways without involvement of [Ca2+]i elevation.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20071101
Title: Glutathione depletion activates mitogen-activated protein kinase (MAPK) pathways that display organ-specific responses and brain protection in mice.
Journal: Free radical biology & medicine 20071101
Title: Baicalein induces cancer cell death and proliferation retardation by the inhibition of CDC2 kinase and survivin associated with opposite role of p38 mitogen-activated protein kinase and AKT.
Journal: Molecular cancer therapeutics 20071101
Title: Prostaglandin E2 induces hypertrophic changes and suppresses alpha-skeletal actin gene expression in rat cardiomyocytes.
Journal: Journal of cardiovascular pharmacology 20071101
Title: Phosphorylation of Stats at Ser727 in renal proximal tubular epithelial cells exposed to cadmium.
Journal: Environmental toxicology and pharmacology 20071101
Title: Phosphatidylinositol 3-kinase, MEK-1 and p38 mediate leptin/interferon-gamma synergistic NOS type II induction in chondrocytes.
Journal: Life sciences 20071027
Title: Functional interdependence at the chromatin level between the MKK6/p38 and IGF1/PI3K/AKT pathways during muscle differentiation.
Journal: Molecular cell 20071026
Title: Macrophage inflammatory protein-1alpha (MIP-1alpha) enhances a receptor activator of nuclear factor kappaB ligand (RANKL) expression in mouse bone marrow stromal cells and osteoblasts through MAPK and PI3K/Akt pathways.
Journal: Molecular and cellular biochemistry 20071001
Title: Modulation of mast cell proteinase-activated receptor expression and IL-4 release by IL-12.
Journal: Immunology and cell biology 20071001
Title: PGE2 inhibits apoptosis in human adenocarcinoma Caco-2 cell line through Ras-PI3K association and cAMP-dependent kinase A activation.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20071001
Title: Delayed and persistent ERK1/2 activation is required for 4-hydroxytamoxifen-induced cell death.
Journal: Steroids 20071001
Title: Areca nut extracts-activated secretion of leukotriene B4, and phosphorylation of p38 mitogen-activated protein kinase and elevated intracellular calcium concentrations in human polymorphonuclear leukocytes.
Journal: Journal of periodontal research 20071001
Title: Pathophysiological role of the activation of p38 mitogen-activated protein kinases in poorly differentiated gastric cancer.
Journal: Pathology international 20071001
Title: Icariin promotes expression of PGC-1alpha, PPARalpha, and NRF-1 during cardiomyocyte differentiation of murine embryonic stem cells in vitro.
Journal: Acta pharmacologica Sinica 20071001
Title: Genistein stimulates osteoblastic differentiation via p38 MAPK-Cbfa1 pathway in bone marrow culture.
Journal: Acta pharmacologica Sinica 20071001
Title: Activation of microglial cells by ceruloplasmin.
Journal: Brain research 20070926
Title: Penta-acetyl geniposide-induced apoptosis involving transcription of NGF/p75 via MAPK-mediated AP-1 activation in C6 glioma cells.
Journal: Toxicology 20070905
Title: Up-regulation of early growth response gene 1 (EGR-1) via ERK1/2 signals attenuates sulindac sulfide-mediated cytotoxicity in the human intestinal epithelial cells.
Journal: Toxicology and applied pharmacology 20070901
Title: Epidermal growth factor receptor signaling modulates apoptosis via p38alpha MAPK-dependent activation of Bax in intestinal epithelial cells.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20070901
Title: Pyridinylimidazole inhibitors of Tie2 kinase.
Journal: Bioorganic & medicinal chemistry letters 20070901
Title: p38 mitogen-activated protein kinase contributes to angiotensin II-stimulated migration of rat aortic smooth muscle cells.
Journal: Journal of pharmacological sciences 20070901
Title: [P38 mitogen-activated protein kinase mediates glucocorticoid receptor function induced by dexamethasone in acute lymphoblastic leukemia cells].
Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics 20070901
Title: Inhibition of p38 mitogen-activated protein kinase attenuates experimental autoimmune hepatitis: involvement of nuclear factor kappa B.
Journal: World journal of gastroenterology 20070821
Title: The role of p38 mitogen-activated kinase (MAPK) in the mechanism regulating cyclooxygenase gene expression in equine leukocytes.
Journal: Veterinary immunology and immunopathology 20070815
Title: Intracisternal administration of mitogen-activated protein kinase inhibitors reduced mechanical allodynia following chronic constriction injury of infraorbital nerve in rats.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20070815
Title: Up-regulation of aldose reductase expression mediated by phosphatidylinositol 3-kinase/Akt and Nrf2 is involved in the protective effect of curcumin against oxidative damage.
Journal: Free radical biology & medicine 20070815
Title: Promotion of cancer cell migration: an insulin-like growth factor (IGF)-independent action of IGF-binding protein-6.
Journal: The Journal of biological chemistry 20070803
Title: Predominant activation of MAP kinases and pro-destructive/pro-inflammatory features by TNF alpha in early-passage synovial fibroblasts via TNF receptor-1: failure of p38 inhibition to suppress matrix metalloproteinase-1 in rheumatoid arthritis.
Journal: Annals of the rheumatic diseases 20070801
Title: Evidence for JNK-dependent up-regulation of proteoglycan synthesis and for activation of JNK1 following cyclical mechanical stimulation in a human chondrocyte culture model.
Journal: Osteoarthritis and cartilage 20070801
Title: Quercetin protects human hepatocytes from ethanol-derived oxidative stress by inducing heme oxygenase-1 via the MAPK/Nrf2 pathways.
Journal: Journal of hepatology 20070801
Title: Maspin augments proteasome inhibitor-induced apoptosis in prostate cancer cells.
Journal: Journal of cellular physiology 20070801
Title: Modulation by simvastatin of iberiotoxin-sensitive, Ca2+-activated K+ channels of porcine coronary artery smooth muscle cells.
Journal: British journal of pharmacology 20070801
Title: Beta-sitosterol-induced-apoptosis is mediated by the activation of ERK and the downregulation of Akt in MCA-102 murine fibrosarcoma cells.
Journal: International immunopharmacology 20070801
Title: Methylglyoxal-induced fibronectin gene expression through Ras-mediated NADPH oxidase activation in renal mesangial cells.
Journal: Nephrology (Carlton, Vic.) 20070801
Title: Expression and function of mixed lineage kinases in dendritic cells.
Journal: International immunology 20070801
Title: D-Psicose inhibits the expression of MCP-1 induced by high-glucose stimulation in HUVECs.
Journal: Life sciences 20070726
Title: Protein kinase C delta regulates the phosphorylation of heat shock protein 27 in human hepatocellular carcinoma.
Journal: Life sciences 20070726
Title: Role of asymmetric dimethylarginine in vascular injury in transgenic mice overexpressing dimethylarginie dimethylaminohydrolase 2.
Journal: Circulation research 20070720
Title: p38 mitogen-activated protein kinase independent SB203580 block of H2O2-induced increase in GABAergic mIPSC amplitude.
Journal: Neuroreport 20070702
Title: Expression of vascular endothelial growth factor by photodynamic therapy with mono-L-aspartyl chlorin e6 (NPe6) in oral squamous cell carcinoma.
Journal: Oral oncology 20070701
Title: Roles of Na+/H+ exchange in regulation of p38 mitogen-activated protein kinase activity and cell death after chemical anoxia in NIH3T3 fibroblasts.
Journal: Pflugers Archiv : European journal of physiology 20070701
Title: Hepatocyte growth factor promotes colonic epithelial regeneration via Akt signaling.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20070701
Title: The onset of labor alters corticotropin-releasing hormone type 1 receptor variant expression in human myometrium: putative role of interleukin-1beta.
Journal: Endocrinology 20070701
Title: Inhibition of p38 mitogen-activated protein kinase-induced apoptosis in cultured mature oligodendrocytes using SB202190 and SB203580.
Journal: Neurochemistry international 20070701
Title: Insulin-like growth factor-I has different effects on myogenin induction and cell cycle progression in human alveolar and embryonal rhabdomyosarcoma cells.
Journal: International journal of oncology 20070701
Title: HIF-1alpha activation by a redox-sensitive pathway mediates cyanide-induced BNIP3 upregulation and mitochondrial-dependent cell death.
Journal: Free radical biology & medicine 20070701
Title: Oxidative stress mediates CoCl(2)-induced prostate tumour cell adhesion: role of protein kinase C and p38 mitogen-activated protein kinase.
Journal: Basic & clinical pharmacology & toxicology 20070701
Title: p38 mitogen-activated protein kinase mediates sidestream cigarette smoke-induced endothelial permeability.
Journal: Journal of pharmacological sciences 20070701
Title: Protective effects of fustin, a flavonoid from Rhus verniciflua Stokes, on 6-hydroxydopamine-induced neuronal cell death.
Journal: Experimental & molecular medicine 20070630
Title: MAPKAPK2-mediated LSP1 phosphorylation and FMLP-induced neutrophil polarization.
Journal: Biochemical and biophysical research communications 20070622
Title: Induction of cyclooxygenase-2 expression by manganese in cultured astrocytes.
Journal: Neurochemistry international 20070601
Title: Carbon black particles increase reactive oxygen species formation in rat alveolar macrophages in vitro.
Journal: Archives of toxicology 20070601
Title: Evidence for the involvement of p38 MAP kinase in the action of the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA).
Journal: Investigational new drugs 20070601
Title: Pravastatin induces thrombomodulin expression in TNFalpha-treated human aortic endothelial cells by inhibiting Rac1 and Cdc42 translocation and activity.
Journal: Journal of cellular biochemistry 20070601
Title: Role of p38 mitogen-activated protein kinase pathway in estrogen-mediated cardioprotection following trauma-hemorrhage.
Journal: American journal of physiology. Heart and circulatory physiology 20070601
Title: Apoptotic effect of 3,4-dihydroxybenzoic acid on human gastric carcinoma cells involving JNK/p38 MAPK signaling activation.
Journal: International journal of cancer 20070601
Title: Optimal reactive oxygen species concentration and p38 MAP kinase are required for coronary collateral growth.
Journal: American journal of physiology. Heart and circulatory physiology 20070601
Title: Decreased MAPK- and PGE2-dependent IL-11 production in Gialpha2-/- colonic myofibroblasts.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20070601
Title: Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.
Journal: European journal of pharmacology 20070601
Title: Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide.
Journal: The Biochemical journal 20070601
Title: Acrolein induces cyclooxygenase-2 and prostaglandin production in human umbilical vein endothelial cells: roles of p38 MAP kinase.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20070601
Title: Hypoxia-induced apoptosis and tube breakdown are regulated by p38 MAPK but not by caspase cascade in an in vitro capillary model composed of human endothelial cells.
Journal: Journal of cellular physiology 20070601
Title: Effect of wine phenolics on cytokine-induced C-reactive protein expression.
Journal: Journal of thrombosis and haemostasis : JTH 20070601
Title: Role for TGF-beta in cyclosporine-induced modulation of renal epithelial barrier function.
Journal: Journal of the American Society of Nephrology : JASN 20070601
Title: Novel mechanisms of valsartan on the treatment of acute myocardial infarction through inhibition of the antiadhesion molecule periostin.
Journal: Hypertension (Dallas, Tex. : 1979) 20070601
Title: Spleen tyrosine kinase participates in Src-mediated migration and proliferation by PDGF-BB in rat aortic smooth muscle cells.
Journal: Archives of pharmacal research 20070601
Title: Cadmium stimulates MAPKs and Hsp27 phosphorylation in bovine adrenal chromaffin cells.
Journal: Toxicology 20070505
Title: Role of mitogen-activated protein kinase (MAPK) in troglitazone-induced osteoblastic cell death.
Journal: Toxicology 20070505
Title: Role of p38 mitogen-activated protein kinases in cardioprotection of morphine preconditioning.
Journal: Chinese medical journal 20070505
Title: Synthesis, biological testing, and binding mode prediction of 6,9-diarylpurin-8-ones as p38 MAP kinase inhibitors.
Journal: Journal of medicinal chemistry 20070503
Title: Induced secretion of insulin-like growth factor binding protein-1 (IGFBP-1) in human hepatoma cell HepG2 by rubratoxin B.
Journal: Archives of toxicology 20070501
Title: Inhibitory effect of TNF-alpha on the intestinal absorption of galactose.
Journal: Journal of cellular biochemistry 20070501
Title: P38 and ERK mitogen-activated protein kinases mediate acrolein-induced apoptosis in Chinese hamster ovary cells.
Journal: Cellular signalling 20070501
Title: Molecular mechanisms involved in interleukin-4-induced human neutrophils: expression and regulation of suppressor of cytokine signaling.
Journal: Journal of leukocyte biology 20070501
Title: Characterization of the relaxant response to N,N'-dipropyl-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine in porcine coronary arteries.
Journal: The Journal of pharmacology and experimental therapeutics 20070501
Title: Inhibition of p38 mitogen activated protein kinase activation and mutant SOD1(G93A)-induced motor neuron death.
Journal: Neurobiology of disease 20070501
Title: IKappaB-kinase/nuclear factor-kappaB signaling prevents thermal injury-induced gut damage by inhibiting c-Jun NH2-terminal kinase activation.
Journal: Critical care medicine 20070501
Title: Activation of intracellular signaling pathways is necessary for an increase in VDR expression and its nuclear translocation.
Journal: FEBS letters 20070501
Title: Nitrofen suppresses cell proliferation and promotes mitochondria-mediated apoptosis in type II pneumocytes.
Journal: Acta pharmacologica Sinica 20070501
Title: Hydroquinone, a reactive metabolite of benzene, reduces macrophage-mediated immune responses.
Journal: Molecules and cells 20070430
Title: S1P stimulates chemotactic migration and invasion in OVCAR3 ovarian cancer cells.
Journal: Biochemical and biophysical research communications 20070427
Title: P2X7 receptor mediated phosphorylation of p38MAP kinase in the hippocampus.
Journal: Biochemical and biophysical research communications 20070406
Title: (-)-Epigallocatechin gallate suppresses endothelin-1-induced interleukin-6 synthesis in osteoblasts: inhibition of p44/p42 MAP kinase activation.
Journal: FEBS letters 20070403
Title: Differential regulation of indoleamine 2,3-dioxygenase by lipopolysaccharide and interferon gamma in murine bone marrow derived dendritic cells.
Journal: FEBS letters 20070403
Title: Regulation of lipopolysaccharide-induced increases in neutrophil glucose uptake.
Journal: American journal of physiology. Lung cellular and molecular physiology 20070401
Title: p38 mitogen-activated protein kinase mediates adenosine-induced alterations in myocardial glucose utilization via 5'-AMP-activated protein kinase.
Journal: American journal of physiology. Heart and circulatory physiology 20070401
Title: Syk contributes to PDGF-BB-mediated migration of rat aortic smooth muscle cells via MAPK pathways.
Journal: Cardiovascular research 20070401
Title: Cytokine upregulation of proteinase-activated-receptors 2 and 4 expression mediated by p38 MAP kinase and inhibitory kappa B kinase beta in human endothelial cells.
Journal: British journal of pharmacology 20070401
Title: Blockade of p38 mitogen-activated protein kinase pathway ameliorates delayed intestinal transit in burned rats.
Journal: American journal of surgery 20070401
Title: Endothelin-1 induces contraction via a Syk-mediated p38 mitogen-activated protein kinase pathway in rat aortic smooth muscle.
Journal: Journal of pharmacological sciences 20070401
Title: Flashlamp pulsed-dye laser suppressed TGF-beta1 expression and proliferation in cultured keloid fibroblasts is mediated by MAPK pathway.
Journal: Lasers in surgery and medicine 20070401
Title: Interaction of interleukin-7 and interleukin-3 with the CXCL12-induced proliferation of B-cell progenitor acute lymphoblastic leukemia.
Journal: Haematologica 20070401
Title: Endotoxin-induced activation of equine platelets: evidence for direct activation of p38 MAPK pathways and vasoactive mediator production.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20070401
Title: From five- to six-membered rings: 3,4-diarylquinolinone as lead for novel p38MAP kinase inhibitors.
Journal: Journal of medicinal chemistry 20070322
Title: Thalidomide destabilizes cyclooxygenase-2 mRNA by inhibiting p38 mitogen-activated protein kinase and cytoplasmic shuttling of HuR.
Journal: European journal of pharmacology 20070308
Title: Sciatic nerve ligation-induced proliferation of spinal cord astrocytes is mediated by kappa opioid activation of p38 mitogen-activated protein kinase.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070307
Title: Cyclic nucleotide response element binding (CREB) protein activation is involved in K562 erythroleukemia cells differentiation.
Journal: Journal of cellular biochemistry 20070301
Title: Mitogen-activated protein kinases, Erk and p38, phosphorylate and regulate Foxo1.
Journal: Cellular signalling 20070301
Title: p38 activation in uninjured primary afferent neurons and in spinal microglia contributes to the development of neuropathic pain induced by selective motor fiber injury.
Journal: Experimental neurology 20070301
Title: Suppression of endoplasmic reticulum stress-induced caspase activation and cell death by the overexpression of Bcl-xL or Bcl-2.
Journal: Journal of biochemistry 20070301
Title: Green tea polyphenols reduce autoimmune symptoms in a murine model for human Sjogren's syndrome and protect human salivary acinar cells from TNF-alpha-induced cytotoxicity.
Journal: Autoimmunity 20070301
Title: Opposing effects of ERK and p38 MAP kinases on HeLa cell apoptosis induced by dipyrithione.
Journal: Molecules and cells 20070227
Title: Iron causes interactions of TAK1, p21ras, and phosphatidylinositol 3-kinase in caveolae to activate IkappaB kinase in hepatic macrophages.
Journal: The Journal of biological chemistry 20070223
Title: Proteasome inhibition induces glutathione synthesis and protects cells from oxidative stress: relevance to Parkinson disease.
Journal: The Journal of biological chemistry 20070216
Title: p38MAPK activation is involved in androgen-independent proliferation of human prostate cancer cells by regulating IL-6 secretion.
Journal: Biochemical and biophysical research communications 20070216
Title: Myricetin induces human osteoblast differentiation through bone morphogenetic protein-2/p38 mitogen-activated protein kinase pathway.
Journal: Biochemical pharmacology 20070215
Title: Propionate induces pH(i) changes through calcium flux, ERK1/2, p38, and PKC in bovine neutrophils.
Journal: Veterinary immunology and immunopathology 20070215
Title: Cell stress modulates the function of splicing regulatory protein RBM4 in translation control.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20070213
Title: HIV-1 coreceptors CCR5 and CXCR4 both mediate neuronal cell death but CCR5 paradoxically can also contribute to protection.
Journal: Cell death and differentiation 20070201
Title: Feedback control of MKP-1 expression by p38.
Journal: Cellular signalling 20070201
Title: Involvement of microtubules, p38, and Rho kinases pathway in 2-methoxyestradiol-induced lung vascular barrier dysfunction.
Journal: American journal of physiology. Lung cellular and molecular physiology 20070201
Title: A novel pathway for transcriptional regulation of alpha-synuclein.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070201
Title: Paroxetine-induced apoptosis in human osteosarcoma cells: activation of p38 MAP kinase and caspase-3 pathways without involvement of [Ca2+]i elevation.
Journal: Toxicology and applied pharmacology 20070201
Title: Cu2+ and acute thermal stress induce protective events via the p38-MAPK signalling pathway in the perfused Rana ridibunda heart.
Journal: The Journal of experimental biology 20070201
Title: p38 MAP kinase regulation of oligodendrocyte differentiation with CREB as a potential target.
Journal: Neurochemical research 20070201
Title: Intrinsically active variants of all human p38 isoforms.
Journal: The FEBS journal 20070201
Title: The role of chrysin and the ah receptor in induction of the human UGT1A1 gene in vitro and in transgenic UGT1 mice.
Journal: Hepatology (Baltimore, Md.) 20070201
Title: Macrostemonoside A promotes visfatin expression in 3T3-L1 cells.
Journal: Biological & pharmaceutical bulletin 20070201
Title: Intestinal D-galactose transport in an endotoxemia model in the rabbit.
Journal: The Journal of membrane biology 20070201
Title: Signaling of mitochondrial biogenesis following oxidant injury.
Journal: The Journal of biological chemistry 20070126
Title: The regulation of ATF3 gene expression by mitogen-activated protein kinases.
Journal: The Biochemical journal 20070115
Title: Epidermal growth factor up-regulates transforming growth factor-beta receptor type II in human dermal fibroblasts via p38 mitogen-activated protein kinase pathway.
Journal: Biochemical and biophysical research communications 20070105
Title: The role of the NADPH oxidase complex, p38 MAPK, and Akt in regulating human monocyte/macrophage survival.
Journal: American journal of respiratory cell and molecular biology 20070101
Title: Leptin represses matrix metalloproteinase-1 gene expression in LX2 human hepatic stellate cells.
Journal: Journal of hepatology 20070101
Title: Prostaglandin E2 activates Stat3 in neonatal rat ventricular cardiomyocytes: A role in cardiac hypertrophy.
Journal: Cardiovascular research 20070101
Title: Sulindac-derived reactive oxygen species induce apoptosis of human multiple myeloma cells via p38 mitogen activated protein kinase-induced mitochondrial dysfunction.
Journal: Apoptosis : an international journal on programmed cell death 20070101
Title: Effects of mitogen-activated protein kinase inhibitors on tumor necrosis factor-alpha gene expression and apoptosis induction in cultured human fetal membrane chorion cells infected with influenza virus.
Journal: Intervirology 20070101
Title: Serum amyloid A induces WISH cell apoptosis.
Journal: Acta pharmacologica Sinica 20070101
Title: Combination treatment with arsenic trioxide and phytosphingosine enhances apoptotic cell death in arsenic trioxide-resistant cancer cells.
Journal: Molecular cancer therapeutics 20070101
Title: The role of p38 mitogen-activated protein kinase in regulating interleukin-10 gene expression in Burkitt's lymphoma cell lines.
Journal: Microbiology and immunology 20070101
Title: Involvement of glycogen synthase kinase-3beta in palmitate-induced human umbilical vein endothelial cell apoptosis.
Journal: Journal of vascular research 20070101
Title: [The role of p38 MAPK in gastrin-induced u-PA expression in human colon cancer cells].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20070101
Title: Interleukin-6 and cyclic AMP stimulate release of cathepsin B in human osteoblasts.
Journal: Immunopharmacology and immunotoxicology 20070101
Title: Epigallocatechin-3-O-gallate inhibits the angiotensin II-induced adhesion molecule expression in human umbilical vein endothelial cell via inhibition of MAPK pathways.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101
Title: Ras activation modulates methylglyoxal-induced mesangial cell apoptosis through superoxide production.
Journal: Renal failure 20070101
Title: Ca2+ stimulates COX-2 expression through calcium-sensing receptor in fibroblasts.
Journal: Biochemical and biophysical research communications 20061229
Title: Design, synthesis, and biological evaluation of phenylamino-substituted 6,11-dihydro-dibenzo[b,e]oxepin-11-ones and dibenzo[a,d]cycloheptan-5-ones: novel p38 MAP kinase inhibitors.
Journal: Journal of medicinal chemistry 20061228
Title: The heat shock protein inhibitor KNK437 induces neurite outgrowth in PC12 cells.
Journal: Neuroscience letters 20061227
Title: Involvement of MAP kinases in lipopolysaccharide-induced histamine production in RAW 264 cells.
Journal: Life sciences 20061203
Title: Involvement of p38 MAP kinase and Smad3 in TGF-beta-mediated mast cell functions.
Journal: Cellular signalling 20061201
Title: Signal pathways involved in the regulation of prostaglandin E synthase-1 in human gingival fibroblasts.
Journal: Cellular signalling 20061201
Title: ERK1/2 and p38-MAPK signalling pathways, through MSK1, are involved in NF-kappaB transactivation during oxidative stress in skeletal myoblasts.
Journal: Cellular signalling 20061201
Title: Galpha13 mediates activation of the cytosolic phospholipase A2alpha through fine regulation of ERK phosphorylation.
Journal: Cellular signalling 20061201
Title: Low cell cholesterol levels increase NFkappaB activity through a p38 MAPK-dependent mechanism.
Journal: Cellular signalling 20061201
Title: Bone marrow derived mast cell acquire responsiveness to substance P with Ca(2+) signals and release of leukotriene B(4) via mitogen-activated protein kinase.
Journal: Journal of neuroimmunology 20061201
Title: Species and response dependent differences in the effects of MAPK inhibitors on P2X(7) receptor function.
Journal: British journal of pharmacology 20061201
Title: The c-Jun-N-terminal-Kinase inhibitor SP600125 enhances the butyrate derivative D1-induced apoptosis via caspase 8 activation in Kasumi 1 t(8;21) acute myeloid leukaemia cells.
Journal: British journal of haematology 20061201
Title: Interleukin-1beta up-regulates inducible nitric oxide by way of phosphoinositide 3-kinase-dependent in a cochlear cell model.
Journal: The Laryngoscope 20061201
Title: In vitro evidence for role of ERK, p38, and JNK in exocrine pancreatic cytokine production.
Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20061201
Title: [Signaling pathways in expression of inducible nitric oxide synthase induced by high mobility group box 1 in rat alveolar macrophages].
Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20061201
Title: [The role of MAPK/ERK1/2 signaling pathway in aldosterone stimulated transforming growth factor-beta1 synthesis in renal tubular epithelial cells].
Journal: Zhonghua yi xue za zhi 20061128
Title: Emodin inhibits TNF alpha-induced MMP-1 expression through suppression of activator protein-1 (AP-1).
Journal: Life sciences 20061125
Title: p38 mitogen-activated protein kinase inhibitor SB203580 reverses the antianalgesia induced by dextro-morphine or morphine in the mouse spinal cord.
Journal: European journal of pharmacology 20061121
Title: A novel role of hypoxia-inducible factor in cobalt chloride- and hypoxia-mediated expression of IL-8 chemokine in human endothelial cells.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20061115
Title: Oxidative stress induces premature senescence by stimulating caveolin-1 gene transcription through p38 mitogen-activated protein kinase/Sp1-mediated activation of two GC-rich promoter elements.
Journal: Cancer research 20061115
Title: DLPC and SAMe prevent alpha1(I) collagen mRNA up-regulation in human hepatic stellate cells, whether caused by leptin or menadione.
Journal: Biochemical and biophysical research communications 20061110
Title: The preantral granulosa cell to cumulus cell transition in the mouse ovary: development of competence to undergo expansion.
Journal: Developmental biology 20061101
Title: Activation of mitogen-activated protein kinases is essential for hydrogen peroxide -induced apoptosis in retinal pigment epithelial cells.
Journal: Apoptosis : an international journal on programmed cell death 20061101
Title: Cannabinoid receptor-mediated apoptosis induced by R(+)-methanandamide and Win55,212-2 is associated with ceramide accumulation and p38 activation in mantle cell lymphoma.
Journal: Molecular pharmacology 20061101
Title: Vascular endothelial growth factor expression in monocytes from patients with primary antiphospholipid syndrome.
Journal: Journal of thrombosis and haemostasis : JTH 20061101
Title: p38MAPK inhibitor SB203580 sensitizes human SNU-C4 colon cancer cells to exisulind-induced apoptosis.
Journal: Oncology reports 20061101
Title: Involvement of p38 MAP kinase in not only activation of the phagocyte NADPH oxidase induced by formyl-methionyl-leucyl-phenylalanine but also determination of the extent of the activity.
Journal: Journal of biochemistry 20061101
Title: P38 MAPK protects against TNF-alpha-provoked apoptosis in LNCaP prostatic cancer cells.
Journal: Apoptosis : an international journal on programmed cell death 20061101
Title: Bone marrow cells have a potent anti-ischemic effect against myocardial cell death in humans.
Journal: The Journal of thoracic and cardiovascular surgery 20061101
Title: Inhibition of p38 mitogen-activated protein kinase and transforming growth factor-beta1/Smad signaling pathways modulates the development of fibrosis in adriamycin-induced nephropathy.
Journal: The American journal of pathology 20061101
Title: Phorbol ester-induced contraction through p38 mitogen-activated protein kinase is diminished in aortas from DOCA-salt hypertensive rats.
Journal: Archives of pharmacal research 20061101
Title: Cardiotrophin-1 induces interleukin-6 synthesis in human umbilical vein endothelial cells.
Journal: Cytokine 20061101
Title: Ketamine-induced cardiac depression is associated with increase in [Mg2+]i and activation of p38 MAP kinase and ERK 1/2 in guinea pig.
Journal: Biochemical and biophysical research communications 20061020
Title: Tristetraprolin regulates Cyclin D1 and c-Myc mRNA stability in response to rapamycin in an Akt-dependent manner via p38 MAPK signaling.
Journal: Oncogene 20061012
Title: Honokiol causes the p21WAF1-mediated G(1)-phase arrest of the cell cycle through inducing p38 mitogen activated protein kinase in vascular smooth muscle cells.
Journal: FEBS letters 20061002
Title: Diabetes-induced mechanical hyperalgesia involves spinal mitogen-activated protein kinase activation in neurons and microglia via N-methyl-D-aspartate-dependent mechanisms.
Journal: Molecular pharmacology 20061001
Title: Inhibition of p38 mitogen-activated protein kinase attenuates left ventricular dysfunction by mediating pro-inflammatory cardiac cytokine levels in a mouse model of diabetes mellitus.
Journal: Diabetologia 20061001
Title: Signal transduction pathways involved in the stimulation of tissue type plasminogen activator by interleukin-1alpha and Porphyromonas gingivalis in human osteosarcoma cells.
Journal: Journal of periodontal research 20061001
Title: Meat hydrolysate and essential amino acid-induced glucagon-like peptide-1 secretion, in the human NCI-H716 enteroendocrine cell line, is regulated by extracellular signal-regulated kinase1/2 and p38 mitogen-activated protein kinases.
Journal: The Journal of endocrinology 20061001
Title: The synthetic cannabinoid WIN 55,212-2 increases COX-2 expression and PGE2 release in murine brain-derived endothelial cells following Theiler's virus infection.
Journal: Biochemical pharmacology 20060928
Title: Characterisation of the relaxant response to raloxifene in porcine coronary arteries.
Journal: European journal of pharmacology 20060918
Title: Homogeneous time-resolved fluorescence and its applications for kinase assays in drug discovery.
Journal: Analytical biochemistry 20060915
Title: COX-2 is associated with cadmium-induced ICAM-1 expression in cerebrovascular endothelial cells.
Journal: Toxicology letters 20060910
Title: Multiple activation mechanisms of p38alpha mitogen-activated protein kinase.
Journal: The Journal of biological chemistry 20060908
Title: p38 and ERK MAP kinase mediates iron chelator-induced apoptosis and -suppressed differentiation of immortalized and malignant human oral keratinocytes.
Journal: Life sciences 20060905
Title: Differential transcriptional responses of keloid and normal keratinocytes to serum stimulation.
Journal: The Journal of surgical research 20060901
Title: Modulation by the steroid/thyroid hormone superfamily of TGF-beta-stimulated VEGF release from vascular smooth muscle cells.
Journal: Journal of cellular biochemistry 20060901
Title: Immune regulation of 25-hydroxyvitamin D-1alpha-hydroxylase in human monocytic THP1 cells: mechanisms of interferon-gamma-mediated induction.
Journal: The Journal of clinical endocrinology and metabolism 20060901
Title: p38 MAP kinase mediates apoptosis through phosphorylation of BimEL at Ser-65.
Journal: The Journal of biological chemistry 20060901
Title: p38 MAPK downregulates phosphorylation of Bad in doxorubicin-induced endothelial apoptosis.
Journal: Biochemical and biophysical research communications 20060901
Title: Intracellular signal transduction for migration and actin remodeling in vascular smooth muscle cells after sphingosylphosphorylcholine stimulation.
Journal: American journal of physiology. Heart and circulatory physiology 20060901
Title: Phase II enzymes induction blocks the enhanced IgE production in B cells by diesel exhaust particles.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20060901
Title: PPARgamma phosphorylation mediated by JNK MAPK: a potential role in macrophage-derived foam cell formation.
Journal: Acta pharmacologica Sinica 20060901
Title: Increase in production of matrix metalloproteinase 13 by human articular chondrocytes due to stimulation with S100A4: Role of the receptor for advanced glycation end products.
Journal: Arthritis and rheumatism 20060901
Title: Regulation of peripheral inflammation by spinal p38 MAP kinase in rats.
Journal: PLoS medicine 20060901
Title: Oxidative stress induces phosphoenolpyruvate carboxykinase expression in H4IIE cells.
Journal: Bioscience, biotechnology, and biochemistry 20060901
Title: Differential roles of MAP kinases in atorvastatin-induced VEGF release in cardiac myocytes.
Journal: Life sciences 20060815
Title: The development of novel C-2, C-8, and N-9 trisubstituted purines as inhibitors of TNF-alpha production.
Journal: Bioorganic & medicinal chemistry letters 20060815
Title: Ligustilide inhibits vascular smooth muscle cells proliferation.
Journal: European journal of pharmacology 20060807
Title: p38 mitogen-activated protein kinase mediates the sustained phase of hypoxic pulmonary vasoconstriction and plays a role in phase I vasodilation.
Journal: The Journal of surgical research 20060801
Title: Bile acids induce adhesion molecule expression in endothelial cells through activation of reactive oxygen species, NF-kappaB, and p38.
Journal: American journal of physiology. Heart and circulatory physiology 20060801
Title: Pharmacological and molecular characterization of the mechanisms involved in prostaglandin E2-induced mouse paw edema.
Journal: The Journal of pharmacology and experimental therapeutics 20060801
Title: Copper-induced stimulation of extracellular signal-regulated kinase in trout hepatocytes: the role of reactive oxygen species, Ca2+, and cell energetics and the impact of extracellular signal-regulated kinase signaling on apoptosis and necrosis.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060801
Title: AUF-1 mediates inhibition by nitric oxide of lipopolysaccharide-induced matrix metalloproteinase-9 expression in cultured astrocytes.
Journal: Journal of neuroscience research 20060801
Title: p38 Mitogen-activated protein kinase up-regulates LPS-induced NF-kappaB activation in the development of lung injury and RAW 264.7 macrophages.
Journal: Toxicology 20060801
Title: House dust mite allergen Der p 1 elevates the release of inflammatory cytokines and expression of adhesion molecules in co-culture of human eosinophils and bronchial epithelial cells.
Journal: International immunology 20060801
Title: No evidence for an involvement of the p38 and JNK mitogen-activated protein in inflammatory bowel diseases.
Journal: Digestive diseases and sciences 20060801
Title: Hyperglycemia accelerated endothelial progenitor cell senescence via the activation of p38 mitogen-activated protein kinase.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20060801
Title: The regulatory mechanism by which interleukin-6 stimulates GH-gene expression in rat GH3 cells.
Journal: The Journal of endocrinology 20060801
Title: Participation of superoxide in neutrophil activation and cytokine production.
Journal: Biochimica et biophysica acta 20060801
Title: High throughput screening identified a substituted imidazole as a novel RANK pathway-selective osteoclastogenesis inhibitor.
Journal: Assay and drug development technologies 20060801
Title: Enzyme fragment complementation binding assay for p38alpha mitogen-activated protein kinase to study the binding kinetics of enzyme inhibitors.
Journal: Assay and drug development technologies 20060801
Title: Dipyridamole activation of mitogen-activated protein kinase phosphatase-1 mediates inhibition of lipopolysaccharide-induced cyclooxygenase-2 expression in RAW 264.7 cells.
Journal: European journal of pharmacology 20060717
Title: Protein tyrosine kinase and p38 MAP kinase pathways are involved in stimulation of matrix metalloproteinase-9 by TNF-alpha in human monocytes.
Journal: Immunology letters 20060715
Title: Peroxisome proliferator-activated receptor gamma as a molecular target of resveratrol-induced modulation of polyamine metabolism.
Journal: Cancer research 20060715
Title: p44/42 MAP kinase and c-Jun N-terminal kinase contribute to the up-regulation of caspase-3 in manganese-induced apoptosis in PC12 cells.
Journal: Brain research 20060712
Title: Manganese modulates pro-inflammatory gene expression in activated glia.
Journal: Neurochemistry international 20060701
Title: Serum amyloid A induces contrary immune responses via formyl peptide receptor-like 1 in human monocytes.
Journal: Molecular pharmacology 20060701
Title: Nitric oxide and p38 MAP kinase mediate shear stress-dependent inhibition of MMP-2 production in microvascular endothelial cells.
Journal: Journal of cellular physiology 20060701
Title: Endothelin-1 activates Homer 1alpha expression via mitogen-activated protein kinase in cardiac myocytes.
Journal: International journal of molecular medicine 20060701
Title: Oxidized-HDL3 modulates the expression of Cox-2 in human endothelial cells.
Journal: International journal of molecular medicine 20060701
Title: IL-25 regulates the expression of adhesion molecules on eosinophils: mechanism of eosinophilia in allergic inflammation.
Journal: Allergy 20060701
Title: Interleukin (IL)-4 and IL-13 up-regulate monocyte chemoattractant protein-1 expression in human bronchial epithelial cells: involvement of p38 mitogen-activated protein kinase, extracellular signal-regulated kinase 1/2 and Janus kinase-2 but not c-Jun NH2-terminal kinase 1/2 signalling pathways.
Journal: Clinical and experimental immunology 20060701
Title: Role of the p38 mitogen-activated protein kinase pathway in the generation of arsenic trioxide-dependent cellular responses.
Journal: Cancer research 20060701
Title: p38 Mitogen-activated protein kinase mediates IL-8 induction by the ribotoxin deoxynivalenol in human monocytes.
Journal: Toxicology and applied pharmacology 20060615
Title: Halofuginone induces matrix metalloproteinases in rat hepatic stellate cells via activation of p38 and NFkappaB.
Journal: The Journal of biological chemistry 20060602
Title: Mitogen-activated protein kinases mediate arsenic-induced down-regulation of survivin in human lung adenocarcinoma cells.
Journal: Archives of toxicology 20060601
Title: Infectious bursal disease virus infection induces macrophage activation via p38 MAPK and NF-kappaB pathways.
Journal: Virus research 20060601
Title: Inverse regulation of preproendothelin-1 and endothelin-converting enzyme-1beta genes in cardiac cells by mechanical load.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20060601
Title: TGF-beta1-induced thrombospondin-1 expression through the p38 MAPK pathway is abolished by fluvastatin in human coronary artery smooth muscle cells.
Journal: Vascular pharmacology 20060601
Title: HGF synthesis in human lung fibroblasts is regulated by oncostatin M.
Journal: American journal of physiology. Lung cellular and molecular physiology 20060601
Title: Functional analyses of C13orf19/P38IP in prostate cell lines.
Journal: Oncology reports 20060601
Title: Mitigation of direct neurotoxic effects of lidocaine and amitriptyline by inhibition of p38 mitogen-activated protein kinase in vitro and in vivo.
Journal: Anesthesiology 20060601
Title: Activation of human polymorphonuclear neutrophils by streptolysin O from Streptococcus pyogenes leads to the release of proinflammatory mediators.
Journal: Thrombosis and haemostasis 20060601
Title: Cytokines differentially regulate ICAM-1 and VCAM-1 expression on human gingival fibroblasts.
Journal: Clinical and experimental immunology 20060601
Title: Importance of the stress kinase p38alpha in mediating the direct cytotoxic effects of the thalidomide analogue, CPS49, in cancer cells and endothelial cells.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060601
Title: Mechanical hyperalgesia induced by endothelin-1 in rats is mediated via phospholipase C, protein kinase C, and MAP kinases.
Journal: Experimental biology and medicine (Maywood, N.J.) 20060601
Title: Different signaling pathways are involved in cardiomyocyte survival induced by a Trypanosoma cruzi glycoprotein.
Journal: Microbes and infection 20060601
Title: Dracorhodin perchlorate induces apoptosis in HL-60 cells.
Journal: Journal of Asian natural products research 20060601
Title: Mast cell chymase induces expression of chemokines for neutrophils in eosinophilic EoL-1 cells and mouse peritonitis eosinophils.
Journal: European journal of pharmacology 20060524
Title: MAPKAPK2 and HSP27 are downstream effectors of p38 MAP kinase-mediated matrix metalloproteinase type 2 activation and cell invasion in human prostate cancer.
Journal: Oncogene 20060518
Title: Regulation of Nur77 nuclear export by c-Jun N-terminal kinase and Akt.
Journal: Oncogene 20060518
Title: [Mechanism of signal transduction of differentiation of mesenchymal stem cells into cytokeratin-expressing epidermoid cells].
Journal: Zhonghua yi xue za zhi 20060516
Title: Gi-coupled receptors mediate phosphorylation of CPI-17 and MLC20 via preferential activation of the PI3K/ILK pathway.
Journal: The Biochemical journal 20060515
Title: Adiponectin stimulates proliferation and cytokine secretion in colonic epithelial cells.
Journal: Regulatory peptides 20060515
Title: Involvement of p38 MAPK and Nrf2 in phenolic acid-induced P-form phenol sulfotransferase expression in human hepatoma HepG2 cells.
Journal: Carcinogenesis 20060501
Title: The astroglial-derived S100beta protein stimulates the expression of nitric oxide synthase in rodent macrophages through p38 MAP kinase activation.
Journal: Life sciences 20060501
Title: Lipopolysaccharide induces epithelium- and prostaglandin E(2)-dependent relaxation of mouse isolated trachea through activation of cyclooxygenase (COX)-1 and COX-2.
Journal: The Journal of pharmacology and experimental therapeutics 20060501
Title: Mechanisms underlying lipopolysaccharide-induced kinin B1 receptor up-regulation in the pig iris sphincter in vitro.
Journal: Molecular pharmacology 20060501
Title: Insulin activates hypoxia-inducible factor-1alpha in human and rat vascular smooth muscle cells via phosphatidylinositol-3 kinase and mitogen-activated protein kinase pathways: impairment in insulin resistance owing to defects in insulin signalling.
Journal: Diabetologia 20060501
Title: Regulation of IL-1-induced selective IL-6 release from human mast cells and inhibition by quercetin.
Journal: British journal of pharmacology 20060501
Title: MAP kinase regulation of IP10/CXCL10 chemokine gene expression in microglial cells.
Journal: Brain research 20060501
Title: Streptococcus pyogenes induces epithelial inflammatory responses through NF-kappaB/MAPK signaling pathways.
Journal: Microbes and infection 20060501
Title: Tissue inhibitor of metalloproteinase-3 is up-regulated by transforming growth factor-beta1 in vitro and expressed in fibroblastic foci in vivo in idiopathic pulmonary fibrosis.
Journal: Experimental lung research 20060501
Title: COX-2-mediated stimulation of the lymphangiogenic factor VEGF-C in human breast cancer.
Journal: British journal of cancer 20060424
Title: A specific mechanomodulatory role for p38 MAPK in embryonic joint articular surface cell MEK-ERK pathway regulation.
Journal: The Journal of biological chemistry 20060421
Title: Limb ischemic preconditioning induces brain ischemic tolerance via p38 MAPK.
Journal: Brain research 20060421
Title: Inhibition of S/G2 phase CDK4 reduces mitotic fidelity.
Journal: The Journal of biological chemistry 20060414
Title: Pigment epithelium-derived factor protects retinal pigment epithelium from oxidant-mediated barrier dysfunction.
Journal: Biochemical and biophysical research communications 20060407
Title: Dynamic changes in mitogen-activated protein kinase (MAPK) activities in the corpus luteum of the bonnet monkey (Macaca radiata) during development, induced luteolysis, and simulated early pregnancy: a role for p38 MAPK in the regulation of luteal function.
Journal: Endocrinology 20060401
Title: The effect of PGG-beta-glucan on neutrophil chemotaxis in vivo.
Journal: Journal of leukocyte biology 20060401
Title: The lectin jacalin plus costimulation with anti-CD28 antibody induces phosphorylation of p38 MAPK and IL-4 synthesis-I.
Journal: Journal of leukocyte biology 20060401
Title: Asymmetric dimethylarginine induces apoptosis via p38 MAPK/caspase-3-dependent signaling pathway in endothelial cells.
Journal: Journal of molecular and cellular cardiology 20060401
Title: The effects of ZD1839 (Iressa), a highly selective EGFR tyrosine kinase inhibitor, as a radiosensitiser in bile duct carcinoma cell lines.
Journal: International journal of oncology 20060401
Title: Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells.
Journal: Nature medicine 20060401
Title: Angiotensin II stimulates the synthesis of vascular endothelial growth factor through the p38 mitogen activated protein kinase pathway in cultured mouse podocytes.
Journal: Journal of molecular endocrinology 20060401
Title: Helicobacter pylori extract induces nuclear factor-kappa B, activator protein-1, and cyclooxygenase-2 in esophageal epithelial cells.
Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20060401
Title: 2-Deoxy-D-ribose inhibits hypoxia-induced apoptosis by suppressing the phosphorylation of p38 MAPK.
Journal: Biochemical and biophysical research communications 20060331
Title: Activation of ERK1/2 and p38 kinases by polycyclic aromatic hydrocarbons in rat liver epithelial cells is associated with induction of apoptosis.
Journal: Toxicology and applied pharmacology 20060315
Title: Interleukin-1 beta up-regulates tissue inhibitor of matrix metalloproteinase-1 mRNA and phosphorylation of c-jun N-terminal kinase and p38 in hepatic stellate cells.
Journal: World journal of gastroenterology 20060307
Title: TAB-1 modulates intracellular localization of p38 MAP kinase and downstream signaling.
Journal: The Journal of biological chemistry 20060303
Title: R(+)-methanandamide and other cannabinoids induce the expression of cyclooxygenase-2 and matrix metalloproteinases in human nonpigmented ciliary epithelial cells.
Journal: The Journal of pharmacology and experimental therapeutics 20060301
Title: Involvement of Nrf2, p38, B-Raf, and nuclear factor-kappaB, but not phosphatidylinositol 3-kinase, in induction of hemeoxygenase-1 by dietary polyphenols.
Journal: Molecular pharmacology 20060301
Title: Second-generation inhibitors demonstrate the involvement of p38 mitogen-activated protein kinase in post-transcriptional modulation of inflammatory mediator production in human and rodent airways.
Journal: The Journal of pharmacology and experimental therapeutics 20060301
Title: Opposing effect of p38 MAP kinase and JNK inhibitors on the development of heart failure in the cardiomyopathic hamster.
Journal: Cardiovascular research 20060301
Title: Stimulation of pancreatic beta-cell replication by incretins involves transcriptional induction of cyclin D1 via multiple signalling pathways.
Journal: The Journal of endocrinology 20060301
Title: Heme oxygenase 1 mediates anti-inflammatory effects of 2',4',6'-tris(methoxymethoxy) chalcone.
Journal: European journal of pharmacology 20060217
Title: Matrix metalloproteinase-2 and -9 are induced differently by doxorubicin in H9c2 cells: The role of MAP kinases and NAD(P)H oxidase.
Journal: Cardiovascular research 20060215
Title: Direct effects of leptin on size and extracellular matrix components of human pediatric ventricular myocytes.
Journal: Cardiovascular research 20060215
Title: Modulatory effect of interleukin-1beta on rat isolated basilar artery contraction.
Journal: European journal of pharmacology 20060215
Title: [Regulation of heat shock protein 27/activating transcription factor-5 complex and its implication in podocyte apoptosis induced by high glucose].
Journal: Zhonghua yi xue za zhi 20060214
Title: Role for mitogen-activated protein kinases in phenobarbital-induced expression of cytochrome P450 2B in primary cultures of rat hepatocytes.
Journal: Toxicology letters 20060208
Title: Identification of Op18/stathmin as a potential target of ASK1-p38 MAP kinase cascade.
Journal: Journal of cellular physiology 20060201
Title: Fibroblast growth factor-23 increases mouse PGE2 production in vivo and in vitro.
Journal: American journal of physiology. Renal physiology 20060201
Title: Angiotensin converting enzyme inhibitor attenuates oxidative stress-induced endothelial cell apoptosis via p38 MAP kinase inhibition.
Journal: Clinica chimica acta; international journal of clinical chemistry 20060201
Title: 4-Hydroxynonenal induces rat gamma-glutamyl transpeptidase through mitogen-activated protein kinase-mediated electrophile response element/nuclear factor erythroid 2-related factor 2 signaling.
Journal: American journal of respiratory cell and molecular biology 20060201
Title: Shiga toxin 1-induced cytokine production is mediated by MAP kinase pathways and translation initiation factor eIF4E in the macrophage-like THP-1 cell line.
Journal: Journal of leukocyte biology 20060201
Title: Involvement of COX-2 in VEGF-induced angiogenesis via P38 and JNK pathways in vascular endothelial cells.
Journal: Cardiovascular research 20060201
Title: The roles of Akt and MAPK family members in silymarin's protection against UV-induced A375-S2 cell apoptosis.
Journal: International immunopharmacology 20060201
Title: Porphyromonas gingivalis-related cardiac cell apoptosis was majorly co-activated by p38 and extracellular signal-regulated kinase pathways.
Journal: Journal of periodontal research 20060201
Title: Docosahexaenoic acid consumption inhibits deoxynivalenol-induced CREB/ATF1 activation and IL-6 gene transcription in mouse macrophages.
Journal: The Journal of nutrition 20060201
Title: Inhibition of myocardial apoptosis by ischaemic and beta-adrenergic preconditioning is dependent on p38 MAPK.
Journal: Cardiovascular drugs and therapy 20060201
Title: Activation of p38 mitogen-activated protein kinase in spinal microglia mediates morphine antinociceptive tolerance.
Journal: Brain research 20060119
Title: Low concentrations of nitric oxide (NO) induced cell death in PC12 cells through activation of p38 mitogen-activated protein kinase (p38 MAPK) but not via extracellular signal-regulated kinases (ERK1/2) or c-Jun N-terminal protein kinase (JNK).
Journal: Neuroscience letters 20060116
Title: Phosphorylation of ezrin enhances microvillus length via a p38 MAP-kinase pathway in an immortalized mouse hepatic cell line.
Journal: Experimental cell research 20060115
Title: Posttranscriptional regulation of TNFalpha expression via eukaryotic initiation factor 4E (eIF4E) phosphorylation in mouse macrophages.
Journal: Cytokine 20060107
Title: N-acetyl-cysteine abolishes hydrogen peroxide-induced modification of eukaryotic initiation factor 4F activity via distinct signalling pathways.
Journal: Cellular signalling 20060101
Title: Macrolide antibiotics modulate ERK phosphorylation and IL-8 and GM-CSF production by human bronchial epithelial cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20060101
Title: Cyclooxygenase-2 induction by bradykinin in aortic vascular smooth muscle cells.
Journal: American journal of physiology. Heart and circulatory physiology 20060101
Title: Modulation of CYP1A2 and CYP3A6 catalytic activities by serum from rabbits with a turpentine-induced inflammatory reaction and interleukin 6.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20060101
Title: Small molecular anti-cytokine agents.
Journal: Medicinal research reviews 20060101
Title: c-Jun N-terminal kinase inhibition and alpha-tocopherol protect midbrain dopaminergic neurons from interferon-gamma/lipopolysaccharide-induced injury without affecting nitric oxide production.
Journal: Journal of neuroscience research 20060101
Title: Immune regulation of 25-hydroxyvitamin-D3-1alpha-hydroxylase in human monocytes.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20060101
Title: Topiramate stimulates glucose transport through AMP-activated protein kinase-mediated pathway in L6 skeletal muscle cells.
Journal: The pharmacogenomics journal 20060101
Title: Signalling pathways evoked by alpha1-adrenoceptors in human melanoma cells.
Journal: Cell biochemistry and function 20060101
Title: CD95-induced osteoarthritic chondrocyte apoptosis and necrosis: dependency on p38 mitogen-activated protein kinase.
Journal: Arthritis research & therapy 20060101
Title: Role of extracellular signal-regulated kinase, p38 kinase, and activator protein-1 in transforming growth factor-beta1-induced alpha smooth muscle actin expression in human fetal lung fibroblasts in vitro.
Journal: Lung 20060101
Title: Induction of interleukin-8 secretion and activation of ERK1/2, p38 MAPK signaling pathways by thrombin in dermal fibroblasts.
Journal: The international journal of biochemistry & cell biology 20060101
Title: [Study of drugs against neoplastic metastasis].
Journal: Magyar onkologia 20060101
Title: Toluene diisocyanate (TDI) induces production of inflammatory cytokines and chemokines by bronchial epithelial cells via the epidermal growth factor receptor and p38 mitogen-activated protein kinase pathways.
Journal: Experimental lung research 20060101
Title: TLR2- and TLR4-dependent activation of STAT1 serine phosphorylation in murine macrophages is protein kinase C-delta-independent.
Journal: Journal of endotoxin research 20060101
Title: Mechanoregulation of monocyte chemoattractant protein-1 expression in rat vascular smooth muscle cells.
Journal: Antioxidants & redox signaling 20060101
Title: Elevated reactive oxygen species but not glutathione regulate mercury resistance to AML-2/DX100 cells.
Journal: Immunopharmacology and immunotoxicology 20060101
Title: Regulation of ROMK (Kir 1.1) channel expression in kidney thick ascending limb by hypertonicity: role of TonEBP and MAPK pathways.
Journal: Nephron. Physiology 20060101
Title: ErbB4 activation inhibits MPP+-induced cell death in PC12-ErbB4 cells: involvement of PI3K and Erk signaling.
Journal: Journal of molecular neuroscience : MN 20060101
Title: Morphine reciprocally regulates IL-10 and IL-12 production by monocyte-derived human dendritic cells and enhances T cell activation.
Journal: Molecular medicine (Cambridge, Mass.) 20060101
Title: p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis.
Journal: The Journal of biological chemistry 20051230
Title: Lysophosphatidic acid stimulates cell proliferation in rat chondrocytes.
Journal: Biochemical pharmacology 20051205
Title: Signaling to the DEAD box--regulation of DEAD-box p68 RNA helicase by protein phosphorylations.
Journal: Cellular signalling 20051201
Title: Role of F-actin organization in p38 MAP kinase-mediated apoptosis and necrosis in neonatal rat cardiomyocytes subjected to simulated ischemia and reoxygenation.
Journal: American journal of physiology. Heart and circulatory physiology 20051201
Title: Involvement of histone acetyltransferase (HAT) in ethanol-induced acetylation of histone H3 in hepatocytes: potential mechanism for gene expression.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20051201
Title: Epidermal growth factor stimulation of trophoblast differentiation requires MAPK11/14 (p38 MAP kinase) activation.
Journal: Biology of reproduction 20051201
Title: Two classes of p38alpha MAP kinase inhibitors having a common diphenylether core but exhibiting divergent binding modes.
Journal: Bioorganic & medicinal chemistry letters 20051201
Title: Neuropeptides B and W enhance the growth of human adrenocortical carcinoma-derived NCI-H295 cells by exerting MAPK p42/p44-mediated proliferogenic and antiapoptotic effects.
Journal: International journal of molecular medicine 20051201
Title: Diosgenin, a plant steroid, induces apoptosis in COX-2 deficient K562 cells with activation of the p38 MAP kinase signalling and inhibition of NF-kappaB binding.
Journal: International journal of molecular medicine 20051201
Title: Extracellular signal-regulated kinase is essential for interleukin-1-induced and nuclear factor kappaB-mediated gene expression in insulin-producing INS-1E cells.
Journal: Diabetologia 20051201
Title: Effect of biologic mediators on ciprofloxacin accumulation by gingival fibroblasts.
Journal: Journal of periodontology 20051201
Title: Acute thermal stress and various heavy metals induce tissue-specific pro- or anti-apoptotic events via the p38-MAPK signal transduction pathway in Mytilus galloprovincialis (Lam.).
Journal: The Journal of experimental biology 20051201
Title: Examination of the signal transduction pathways leading to upregulation of tissue type plasminogen activator by Porphyromonas endodontalis in human pulp cells.
Journal: International endodontic journal 20051201
Title: Inhibition of mitogen-activated protein kinase kinase enhances apoptosis induced by arsenic trioxide in human breast cancer MCF-7 cells.
Journal: Clinical and experimental pharmacology & physiology 20051201
Title: [Activation of p38 MAPK signal transduction pathway by burn serum and the expression of VCAM-1 in HUVECs induced by NF-kappaB].
Journal: Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20051201
Title: Differential regulation of corticotropin-releasing factor receptor type 1 (CRF1 receptor) mRNA via protein kinase A and mitogen-activated protein kinase pathways in rat anterior pituitary cells.
Journal: Molecular and cellular endocrinology 20051124
Title: Fundamentally different roles for LFA-1, Mac-1 and alpha4-integrin in neutrophil chemotaxis.
Journal: Journal of cell science 20051115
Title: p38 and EGF receptor kinase-mediated activation of the phosphatidylinositol 3-kinase/Akt pathway is required for Zn2+-induced cyclooxygenase-2 expression.
Journal: American journal of physiology. Lung cellular and molecular physiology 20051101
Title: Insulin-stimulated glucose uptake does not require p38 mitogen-activated protein kinase in adipose tissue or skeletal muscle.
Journal: Diabetes 20051101
Title: Bcl-2 up-regulation and P-p53 down-regulation account for the low sensitivity of murine L929 fibrosarcoma cells to oridonin-induced apoptosis.
Journal: Biological & pharmaceutical bulletin 20051101
Title: Signal pathway of hypoxia-inducible factor-1alpha phosphorylation and its interaction with von Hippel-Lindau tumor suppressor protein during ischemia in MiaPaCa-2 pancreatic cancer cells.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20051101
Title: Globular adiponectin decreases leptin-induced tumor necrosis factor-alpha expression by murine macrophages: involvement of cAMP-PKA and MAPK pathways.
Journal: Cellular immunology 20051101
Title: [Role of MAPK in the migration of human coronary artery smooth muscle cell into three-dimensional fibrin gel].
Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20051101
Title: Inhibitors of mitogen-activated protein kinases downregulate COX-2 expression in human chondrocytes.
Journal: Mediators of inflammation 20051024
Title: Regulation of cAMP-induced arylalkylamine N-acetyltransferase, Period1, and MKP-1 gene expression by mitogen-activated protein kinases in the rat pineal gland.
Journal: Brain research. Molecular brain research 20051003
Title: Inhibition of iNOS gene expression by quercetin is mediated by the inhibition of IkappaB kinase, nuclear factor-kappa B and STAT1, and depends on heme oxygenase-1 induction in mouse BV-2 microglia.
Journal: European journal of pharmacology 20051003
Title: IL-6 activates serum and glucocorticoid kinase via p38alpha mitogen-activated protein kinase pathway.
Journal: American journal of physiology. Cell physiology 20051001
Title: Effects of anthocyanidin on the inhibition of proliferation and induction of apoptosis in human gastric adenocarcinoma cells.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20051001
Title: The role of p38 MAPK activation in auranofin-induced apoptosis of human promyelocytic leukaemia HL-60 cells.
Journal: British journal of pharmacology 20051001
Title: JTT-705 blocks cell proliferation and angiogenesis through p38 kinase/p27(kip1) and Ras/p21(waf1) pathways.
Journal: Atherosclerosis 20051001
Title: Fetal hemoglobin induction by the histone deacetylase inhibitor, scriptaid.
Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20050905
Title: Mitochondrial reactive oxygen species and c-Src play a critical role in hypoxic response in vascular smooth muscle cells.
Journal: Cardiovascular research 20050901
Title: Reduction of insulin-stimulated glucose uptake in L6 myotubes by the protein kinase inhibitor SB203580 is independent of p38MAPK activity.
Journal: Endocrinology 20050901
Title: Induction of competing apoptotic and survival signaling pathways in the macrophage by the ribotoxic trichothecene deoxynivalenol.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050901
Title: Purinergic receptor modulation of BV-2 microglial cell activity: potential involvement of p38 MAP kinase and CREB.
Journal: Journal of neuroimmunology 20050901
Title: Activation of mitogen activated protein kinase pathways and melanogenesis by novel nitro-derivatives of 7-hydroxycomarin in human malignant melanoma cells.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050901
Title: An immunosorbent, nonradioactive p38 MAP kinase assay comparable to standard radioactive liquid-phase assays.
Journal: Analytical biochemistry 20050901
Title: Midazolam suppresses thrombin-induced heat shock protein 27 phosphorylation through inhibition of p38 mitogen-activated protein kinase in cardiac myocytes.
Journal: Journal of cellular biochemistry 20050901
Title: Motorcycle exhaust particles induce IL-8 production through NF-kappaB activation in human airway epithelial cells.
Journal: Journal of toxicology and environmental health. Part A 20050901
Title: Mechanisms involved in the nociception produced by peripheral protein kinase c activation in mice.
Journal: Pain 20050901
Title: Interleukin-10 inhibits lipopolysaccharide-induced survival and extracellular signal-regulated kinase activation in human neutrophils.
Journal: European journal of immunology 20050901
Title: [Effect of selenium on expression of P38 mitogen-activated protein kinase and monocyte chemoattractant protein-1 in diabetic endothelial cells].
Journal: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20050901
Title: Multiple signaling pathways are activated during insulin-like growth factor-I (IGF-I) stimulated breast cancer cell migration.
Journal: Breast cancer research and treatment 20050901
Title: Involvement of extracellular regulated kinase and p38 kinase in hippocampal seizure tolerance.
Journal: Journal of neuroscience research 20050815
Title: Methoxychlor-induced inducible nitric oxide synthase and proinflammatory cytokines expression in macrophages via NF-kappaB, ERK, and p38 mitogen-activated protein kinases.
Journal: Biochemical and biophysical research communications 20050812
Title: p38 mitogen-activated protein kinase (MAPK) first regulates filamentous actin at the 8-16-cell stage during preimplantation development.
Journal: Biology of the cell 20050801
Title: Interleukin-25-induced chemokines and interleukin-6 release from eosinophils is mediated by p38 mitogen-activated protein kinase, c-Jun N-terminal kinase, and nuclear factor-kappaB.
Journal: American journal of respiratory cell and molecular biology 20050801
Title: Polysaccharide purified from Ganoderma lucidum induced activation and maturation of human monocyte-derived dendritic cells by the NF-kappaB and p38 mitogen-activated protein kinase pathways.
Journal: Journal of leukocyte biology 20050801
Title: DNFB activates MAPKs and upregulates CD40 in skin-derived dendritic cells.
Journal: Journal of dermatological science 20050801
Title: WAVE3 promotes cell motility and invasion through the regulation of MMP-1, MMP-3, and MMP-9 expression.
Journal: Experimental cell research 20050801
Title: Proinflammatory cytokines and apoptosis following glutamate-induced excitotoxicity mediated by p38 MAPK in the hippocampus of neonatal rats.
Journal: Journal of neuroimmunology 20050801
Title: The molecular basis for coxib inhibition of p38alpha MAP kinase.
Journal: Bioorganic & medicinal chemistry letters 20050801
Title: Multiple anti-apoptotic pathways stimulated by EGF in cytotrophoblasts.
Journal: Placenta 20050801
Title: Human immunodeficiency virus type 1 envelope glycoprotein 120 induces cyclooxygenase-2 expression in neuroblastoma cells through a nuclear factor-kappaB and activating protein-1 mediated mechanism.
Journal: Journal of neurochemistry 20050801
Title: Innate mechanisms for Bifidobacterium lactis to activate transient pro-inflammatory host responses in intestinal epithelial cells after the colonization of germ-free rats.
Journal: Immunology 20050801
Title: Signaling pathway in nerve growth factor induced histamine release from rat mast cells.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20050801
Title: Mitogen-activated protein kinases (MAPKs) mediate SIN-1/ glucose deprivation-induced death in rat primary astrocytes.
Journal: Archives of pharmacal research 20050801
Title: Ras/MAP kinase pathways are involved in Ras specific apoptosis induced by sodium butyrate.
Journal: Cancer letters 20050728
Title: Histamine induces tissue factor expression: implications for acute coronary syndromes.
Journal: Circulation 20050719
Title: ERK1/2 and p38 regulate trophoblasts differentiation in human term placenta.
Journal: The Journal of physiology 20050715
Title: Involvement of p38 MAP kinase-mediated cytochrome c release on sphingosine-1-phosphate (S1P)- and N-monomethyl-S1P-induced cell death of PC12 cells.
Journal: Biochemical pharmacology 20050715
Title: Characterization of cAMP-dependent proteolysis of GATA-6.
Journal: Biochemical and biophysical research communications 20050715
Title: Eosinophil migration induced by mast cell chymase is mediated by extracellular signal-regulated kinase pathway.
Journal: Biochemical and biophysical research communications 20050715
Title: Radical mediators and mitogen-activated protein kinase signaling in oxygen-dependent radiosensitivity of human tumor cell lines.
Journal: Free radical biology & medicine 20050715
Title: Nitric oxide-induced apoptosis in lymphoblastoid and fibroblast cells dependent on the phosphorylation and activation of p53.
Journal: Cancer research 20050715
Title: Voltage-gated sodium channel Nav1.6 is modulated by p38 mitogen-activated protein kinase.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050713
Title: Cinnamaldehyde-induced apoptosis in human PLC/PRF/5 cells through activation of the proapoptotic Bcl-2 family proteins and MAPK pathway.
Journal: Life sciences 20050708
Title: YC-1-inhibited proliferation of rat mesangial cells through suppression of cyclin D1-independent of cGMP pathway and partially reversed by p38 MAPK inhibitor.
Journal: European journal of pharmacology 20050704
Title: The p53 pathway is synergized by p38 MAPK signaling to mediate 11,11'-dideoxyverticillin-induced G2/M arrest.
Journal: FEBS letters 20050704
Title: p38 MAP kinase inhibition ameliorates cisplatin nephrotoxicity in mice.
Journal: American journal of physiology. Renal physiology 20050701
Title: EGF receptor-dependent JNK activation is involved in arsenite-induced p21Cip1/Waf1 upregulation and endothelial apoptosis.
Journal: American journal of physiology. Heart and circulatory physiology 20050701
Title: MAP kinases in lung endothelial permeability induced by microtubule disassembly.
Journal: American journal of physiology. Lung cellular and molecular physiology 20050701
Title: Polypeptide from Chlamys farreri inhibits murine thymocytes apoptosis and modulates UVB induced signaling pathway activation.
Journal: Life sciences 20050701
Title: p38 mitogen-activated protein kinase contributes to cell cycle regulation by cAMP in FRTL-5 thyroid cells.
Journal: European journal of endocrinology 20050701
Title: A novel role for extracellular signal-regulated kinase 5 and myocyte enhancer factor 2 in medulloblastoma cell death.
Journal: Cancer research 20050701
Title: Inflammatory responses of corneal epithelial cells to Pseudomonas aeruginosa infection.
Journal: Current eye research 20050701
Title: Signal pathway of cytokines produced by reactive oxygen species generated from phorbol myristate acetate-stimulated HMC-1 cells.
Journal: Scandinavian journal of immunology 20050701
Title: Growth suppression of Leydig TM3 cells mediated by aryl hydrocarbon receptor.
Journal: Biochemical and biophysical research communications 20050617
Title: Rapid computational identification of the targets of protein kinase inhibitors.
Journal: Journal of medicinal chemistry 20050616
Title: Possible involvement of phosphatidylinositol 3-kinase/Akt signal pathway in vasopressin-induced HSP27 phosphorylation in aortic smooth muscle A10 cells.
Journal: Archives of biochemistry and biophysics 20050615
Title: alphaB-crystallin is phosphorylated during myocardial infarction: involvement of platelet-derived growth factor-BB.
Journal: Archives of biochemistry and biophysics 20050615
Title: Beta-amyloid-induced apoptosis is associated with cyclooxygenase-2 up-regulation via the mitogen-activated protein kinase-NF-kappaB signaling pathway.
Journal: Free radical biology & medicine 20050615
Title: Inhibition of CREB transcriptional activity in human T lymphocytes by oxidative stress.
Journal: Free radical biology & medicine 20050615
Title: Hibiscus anthocyanins rich extract-induced apoptotic cell death in human promyelocytic leukemia cells.
Journal: Toxicology and applied pharmacology 20050615
Title: Clostridium difficile toxin A regulates inducible cyclooxygenase-2 and prostaglandin E2 synthesis in colonocytes via reactive oxygen species and activation of p38 MAPK.
Journal: The Journal of biological chemistry 20050603
Title: Cross-interactions of two p38 mitogen-activated protein (MAP) kinase inhibitors and two cholecystokinin (CCK) receptor antagonists with the CCK1 receptor and p38 MAP kinase.
Journal: The Journal of biological chemistry 20050603
Title: p38 kinase-mediated transactivation of the epidermal growth factor receptor is required for dedifferentiation of renal epithelial cells after oxidant injury.
Journal: The Journal of biological chemistry 20050603
Title: Temporary blockade of contractility during reperfusion elicits a cardioprotective effect of the p38 MAP kinase inhibitor SB-203580.
Journal: American journal of physiology. Heart and circulatory physiology 20050601
Title: Infection-induced kinin B1 receptors in human pulmonary fibroblasts: role of intact pathogens and p38 mitogen-activated protein kinase-dependent signaling.
Journal: The Journal of pharmacology and experimental therapeutics 20050601
Title: Tristetraprolin regulates the expression of the human inducible nitric-oxide synthase gene.
Journal: Molecular pharmacology 20050601
Title: Artocarpol A stimulation of superoxide anion generation in neutrophils involved the activation of PLC, PKC and p38 mitogen-activated PK signaling pathways.
Journal: British journal of pharmacology 20050601
Title: p38 Mitogen-activated protein kinase (MAPK) is a key mediator in glucocorticoid-induced apoptosis of lymphoid cells: correlation between p38 MAPK activation and site-specific phosphorylation of the human glucocorticoid receptor at serine 211.
Journal: Molecular endocrinology (Baltimore, Md.) 20050601
Title: Inflammatory pathway analysis using a high content screening platform.
Journal: Assay and drug development technologies 20050601
Title: Construction of 4D-QSAR models for use in the design of novel p38-MAPK inhibitors.
Journal: Journal of computer-aided molecular design 20050601
Title: Role of p38 in nitric oxide synthase and cyclooxygenase expression, and nitric oxide and PGE2 synthesis in human gingival fibroblasts stimulated with lipopolysaccharides.
Journal: Life sciences 20050520
Title: Akt regulates thrombin-induced HSP27 phosphorylation in aortic smooth muscle cells: function at a point downstream from p38 MAP kinase.
Journal: Life sciences 20050520
Title: delta-Opioid agonist induced regulation of E2F1 DNA binding activity in NG108-15 cells.
Journal: Brain research. Molecular brain research 20050520
Title: Kinetic studies of small molecule interactions with protein kinases using biosensor technology.
Journal: Analytical biochemistry 20050515
Title: Activation of discoidin domain receptor 1 on CD14-positive bronchoalveolar lavage fluid cells induces chemokine production in idiopathic pulmonary fibrosis.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20050515
Title: Frontal affinity chromatography with MS detection of EphB2 tyrosine kinase receptor. 2. Identification of small-molecule inhibitors via coupling with virtual screening.
Journal: Journal of medicinal chemistry 20050505
Title: The development of monocyclic pyrazolone based cytokine synthesis inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20050502
Title: Activation of p38 MAPKalpha by extracellular pressure mediates the stimulation of macrophage phagocytosis by pressure.
Journal: American journal of physiology. Cell physiology 20050501
Title: B lymphocyte stimulator activates p38 mitogen-activated protein kinase in human Ig class switch recombination.
Journal: American journal of respiratory cell and molecular biology 20050501
Title: Decrease in cytosolic phospholipase A2alpha mRNA levels by reactive oxygen species via MAP kinase pathways in PC12 cells: effects of dopaminergic neurotoxins.
Journal: Cellular signalling 20050501
Title: Simvastatin inhibits MMP-9 secretion from human saphenous vein smooth muscle cells by inhibiting the RhoA/ROCK pathway and reducing MMP-9 mRNA levels.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050501
Title: p38 mitogen-activated protein kinase inhibition attenuates burn-induced liver injury in rats.
Journal: Burns : journal of the International Society for Burn Injuries 20050501
Title: Juzentaihoto, a Kampo medicine, enhances IL-12 production by modulating Toll-like receptor 4 signaling pathways in murine peritoneal exudate macrophages.
Journal: International immunopharmacology 20050501
Title: Orexins modulate the growth of cultured rat adrenocortical cells, acting through type 1 and type 2 receptors coupled to the MAPK p42/p44- and p38-dependent cascades.
Journal: International journal of molecular medicine 20050501
Title: AMP-activated protein kinase signaling stimulates VEGF expression and angiogenesis in skeletal muscle.
Journal: Circulation research 20050429
Title: Stretch-induced cell proliferation is mediated by FAK-MAPK pathway.
Journal: Life sciences 20050429
Title: Inhibition of RICK/nuclear factor-kappaB and p38 signaling attenuates the inflammatory response in a murine model of Crohn disease.
Journal: The Journal of biological chemistry 20050415
Title: Stress-induced platelet-activating factor synthesis in human neutrophils.
Journal: Biochimica et biophysica acta 20050415
Title: MAPKs mediate the activation of cytosolic phospholipase A2 by amyloid beta(25-35) peptide in bovine retina pericytes.
Journal: Biochimica et biophysica acta 20050415
Title: Requirement for ERK activation in acetone extract identified from Bupleurum scorzonerifolium induced A549 tumor cell apoptosis and keratin 8 phosphorylation.
Journal: Life sciences 20050408
Title: Pivotal role of gp91phox-containing NADH oxidase in lipopolysaccharide-induced tumor necrosis factor-alpha expression and myocardial depression.
Journal: Circulation 20050405
Title: Heme oxygenase-1 induction by dieldrin in dopaminergic cells.
Journal: Neuroreport 20050404
Title: N-methyl-D-aspartate and brain-derived neurotrophic factor induce distinct profiles of extracellular signal-regulated kinase, mitogen- and stress-activated kinase, and ribosomal s6 kinase phosphorylation in cortical neurons.
Journal: Molecular pharmacology 20050401
Title: Endofacial competitive inhibition of glucose transporter-4 intrinsic activity by the mitogen-activated protein kinase inhibitor SB203580.
Journal: Endocrinology 20050401
Title: The p38 mitogen-activated protein kinase inhibitor SB203580 reduces glucose turnover by the glucose transporter-4 of 3T3-L1 adipocytes in the insulin-stimulated state.
Journal: Endocrinology 20050401
Title: CGH2466, a combined adenosine receptor antagonist, p38 mitogen-activated protein kinase and phosphodiesterase type 4 inhibitor with potent in vitro and in vivo anti-inflammatory activities.
Journal: British journal of pharmacology 20050401
Title: Phosphorylation-dependent degradation of p300 by doxorubicin-activated p38 mitogen-activated protein kinase in cardiac cells.
Journal: Molecular and cellular biology 20050401
Title: Direct activation of glucose transport in primary human myotubes after activation of peroxisome proliferator-activated receptor delta.
Journal: Diabetes 20050401
Title: [Protective effect of p38 mitogen activated protein kinase inhibitor on organs in sepsis in rats].
Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20050401
Title: Elevated expression of NF-kappaB and Bcl-2 proteins in C2C12 myocytes during myogenesis is affected by PD98059, LY294002 and SB203580.
Journal: Cell biology international 20050401
Title: Bradykinin upregulates IL-8 production in human gingival fibroblasts stimulated by interleukin-1beta and tumor necrosis factor alpha.
Journal: Regulatory peptides 20050330
Title: Regulation of corticotropin-releasing factor receptor type 2beta mRNA by mitogen-activated protein kinases in aortic smooth muscle cells.
Journal: Regulatory peptides 20050330
Title: Acidic extracellular pH induces matrix metalloproteinase-9 expression in mouse metastatic melanoma cells through the phospholipase D-mitogen-activated protein kinase signaling.
Journal: The Journal of biological chemistry 20050325
Title: p38 mitogen-activated protein kinase downregulates endothelial progenitor cells.
Journal: Circulation 20050308
Title: Acute adenosine preconditioning is mediated by p38 MAPK activation in discrete subcellular compartments.
Journal: American journal of physiology. Heart and circulatory physiology 20050301
Title: Factor VIIa stimulates endothelin-1 synthesis in TNF-primed endothelial cells by activation of protease-activated receptor 2.
Journal: Clinical science (London, England : 1979) 20050301
Title: Effects of mercuric chloride on glucose transport in 3T3-L1 adipocytes.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20050301
Title: A small molecule-kinase interaction map for clinical kinase inhibitors.
Journal: Nature biotechnology 20050301
Title: Global kinase screening. Applications of frontal affinity chromatography coupled to mass spectrometry in drug discovery.
Journal: Analytical chemistry 20050301
Title: p38 MAPK and COX2 inhibition modulate human chondrocyte response to TGF-beta.
Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20050301
Title: Hypotonic shock mediation by p38 MAPK, JNK, PKC, FAK, OSR1 and SPAK in osmosensing chloride secreting cells of killifish opercular epithelium.
Journal: The Journal of experimental biology 20050301
Title: Role of gap junctional intercellular communication (GJIC) through p38 and ERK1/2 pathway in the differentiation of rat neuronal stem cells.
Journal: The Journal of veterinary medical science 20050301
Title: Homocysteine promotes p38-dependent chemotaxis in bovine aortic smooth muscle cells.
Journal: Journal of vascular surgery 20050301
Title: Fenofibrate induces apoptotic injury in cultured human hepatocytes by inhibiting phosphorylation of Akt.
Journal: Apoptosis : an international journal on programmed cell death 20050301
Title: Association of the ERK1/2 and p38 kinase pathways with nitric oxide-induced apoptosis and cell cycle arrest in colon cancer cells.
Journal: Cell biology and toxicology 20050301
Title: Novel signaling stimulated by arsenite increases cholesterol metabolism through increases in unphosphorylated steroidogenic acute regulatory (StAR) protein.
Journal: Molecular and cellular endocrinology 20050227
Title: Xenobiotic-induced TNF-alpha expression and apoptosis through the p38 MAPK signaling pathway.
Journal: Toxicology letters 20050215
Title: The p38 SAPK pathway is required for Ha-ras induced in vitro invasion of NIH3T3 cells.
Journal: Experimental cell research 20050215
Title: Inhibition of p38 mitogen-activated protein kinase may decrease intestinal epithelial cell apoptosis and improve intestinal epithelial barrier function after ischemia- reperfusion injury.
Journal: World journal of gastroenterology 20050207
Title: VCAM-1 upregulation via PKCdelta-p38 kinase-linked cascade mediates the TNF-alpha-induced leukocyte adhesion and emigration in the lung airway epithelium.
Journal: American journal of physiology. Lung cellular and molecular physiology 20050201
Title: CD38 cleavage in fMLP- and IL-8-induced chemotaxis is dependent on p38 MAP kinase but independent of p44/42 MAP kinase.
Journal: Cellular signalling 20050201
Title: Cypermethrin blocks a mitochondria-dependent apoptotic signal initiated by deficient N-linked glycosylation within the endoplasmic reticulum.
Journal: Cellular signalling 20050201
Title: Superoxide dismutase inhibits the expression of vascular cell adhesion molecule-1 and intracellular cell adhesion molecule-1 induced by tumor necrosis factor-alpha in human endothelial cells through the JNK/p38 pathways.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20050201
Title: Inhibition of p38 mitogen-activated protein kinase ameliorates cytokine up-regulated shigatoxin-1 toxicity in human brain microvascular endothelial cells.
Journal: The Journal of infectious diseases 20050201
Title: [Involvement of MAPKs and NF-kappaB pathways in Pseudomonas pyocyanin-induced interleukin-8 expression by human airway epithelial cells].
Journal: Wei sheng wu xue bao = Acta microbiologica Sinica 20050201
Title: Sulindac sulfide-induced apoptosis in sinonasal cancer cells.
Journal: Acta oto-laryngologica 20050201
Title: IL-18 enhances SCF production of melanoma cells by regulating ROI and p38 MAPK activity.
Journal: Immunology letters 20050131
Title: Identification of novel p38alpha MAP kinase inhibitors using fragment-based lead generation.
Journal: Journal of medicinal chemistry 20050127
Title: 5-aminoimidazole-4-carboxamide riboside (AICAR) enhances GLUT2-dependent jejunal glucose transport: a possible role for AMPK.
Journal: The Biochemical journal 20050115
Title: Mercury induces multidrug resistance-associated protein gene through p38 mitogen-activated protein kinase.
Journal: Toxicology letters 20050115
Title: Induction of apoptosis and cytokine production in the Jurkat human T cells by deoxynivalenol: role of mitogen-activated protein kinases and comparison to other 8-ketotrichothecenes.
Journal: Toxicology 20050115
Title: Implication of the MAPK pathways in the maturation of human dendritic cells induced by nickel and TNF-alpha.
Journal: Toxicology 20050115
Title: [ERK1/2 and p38 kinases are important regulators in P2Y receptor-mediated prostate cancer invasion].
Journal: Zhonghua yi xue za zhi 20050112
Title: Induction of cytokine mRNA expression in U937 cells by Salmonella typhimurium porins is regulated by different phosphorylation pathways.
Journal: Medical microbiology and immunology 20050101
Title: Cocaine induces apoptosis in fetal rat myocardial cells through the p38 mitogen-activated protein kinase and mitochondrial/cytochrome c pathways.
Journal: The Journal of pharmacology and experimental therapeutics 20050101
Title: p38 MAP kinase inhibitor reverses stress-induced cardiac myocyte dysfunction.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20050101
Title: The temporal relationship between p38 MAPK and HSP27 activation in ischaemic and pharmacological preconditioning.
Journal: Basic research in cardiology 20050101
Title: Secreted beta-amyloid precursor protein activates microglia via JNK and p38-MAPK.
Journal: Neurobiology of aging 20050101
Title: The immunophilin ligand FK506, but not the P38 kinase inhibitor SB203580, improves function of adult rat muscle reinnervated from transplants of embryonic neurons.
Journal: Neuroscience 20050101
Title: Role of p38 MAPK and NF-kB for chemokine release in coculture of human eosinophils and bronchial epithelial cells.
Journal: Clinical and experimental immunology 20050101
Title: Increased interleukin-17 production via a phosphoinositide 3-kinase/Akt and nuclear factor kappaB-dependent pathway in patients with rheumatoid arthritis.
Journal: Arthritis research & therapy 20050101
Title: The noble gas xenon induces pharmacological preconditioning in the rat heart in vivo via induction of PKC-epsilon and p38 MAPK.
Journal: British journal of pharmacology 20050101
Title: Redox regulation of p38 MAPK activation and expression of ICAM-1 and heme oxygenase-1 in human alveolar epithelial (A549) cells.
Journal: Antioxidants & redox signaling 20050101
Title: Interleukin-1beta-induced transdifferentiation of renal proximal tubular cells is mediated by activation of JNK and p38 MAPK.
Journal: Nephron. Experimental nephrology 20050101
Title: Burkholderia pseudomallei invasion and activation of epithelial cells requires activation of p38 mitogen-activated protein kinase.
Journal: Microbial pathogenesis 20050101
Title: Doxorubicin induces cardiomyocyte dysfunction via a p38 MAP kinase-dependent oxidative stress mechanism.
Journal: Cancer detection and prevention 20050101
Title: Activation of p38 mitogen-activated protein kinase is necessary for gemcitabine-induced cytotoxicity in human pancreatic cancer cells.
Journal: Anticancer research 20050101
Title: Octacalcium phosphate crystals directly stimulate expression of inducible nitric oxide synthase through p38 and JNK mitogen-activated protein kinases in articular chondrocytes.
Journal: Arthritis research & therapy 20050101
Title: Interleukin-3, -5, and granulocyte macrophage colony-stimulating factor induce adhesion and chemotaxis of human eosinophils via p38 mitogen-activated protein kinase and nuclear factor kappaB.
Journal: Immunopharmacology and immunotoxicology 20050101
Title: p38 MAPK and NF-kappaB on IL-6 release in human gingival fibroblasts.
Journal: Immunopharmacology and immunotoxicology 20050101
Title: Streptococcus pneumoniae-induced p38 MAPK-dependent phosphorylation of RelA at the interleukin-8 promotor.
Journal: The Journal of biological chemistry 20041217
Title: c-Myc-mediated expression of nucleophosmin/B23 decreases during retinoic acid-induced differentiation of human leukemia HL-60 cells.
Journal: FEBS letters 20041217
Title: Tetrasubstituted imidazole inhibitors of cytokine release: probing substituents in the N-1 position.
Journal: Journal of medicinal chemistry 20041202
Title: Pressure activates rat pancreatic stellate cells.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20041201
Title: A novel UBA and UBX domain protein that binds polyubiquitin and VCP and is a substrate for SAPKs.
Journal: The Biochemical journal 20041201
Title: Role of c-Jun N-terminal kinase on lipopolysaccharide induced maturation of human monocyte-derived dendritic cells.
Journal: International immunology 20041201
Title: The HIV protease inhibitor ritonavir synergizes with butyrate for induction of apoptotic cell death and mediates expression of heme oxygenase-1 in DLD-1 colon carcinoma cells.
Journal: British journal of pharmacology 20041201
Title: Nitric oxide inhibits IgE-dependent cytokine production and Fos and Jun activation in mast cells.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20041201
Title: Effects of lipopolysaccharide and chlorpromazine on glucocorticoid receptor-mediated gene transcription and immunoreactivity: a possible involvement of p38-MAP kinase.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20041201
Title: Blockade by SB203580 of Cyp1a1 induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin, and the possible mechanism: possible involvement of the p38 mitogen-activated protein kinase pathway in shuttling of Ah receptor overexpressed in COS-7 cells.
Journal: Annals of the New York Academy of Sciences 20041201
Title: Salicylic acid alters endothelin-1 binding in intact adult rat ventricular myocytes.
Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20041201
Title: KR-31378 protects cardiac H9c2 cells from chemical hypoxia-induced cell death via inhibition of JNK/p38 MAPK activation.
Journal: The Japanese journal of physiology 20041201
Title: Enteropathogenic Escherichia coli outer membrane proteins induce iNOS by activation of NF-kappaB and MAP kinases.
Journal: Inflammation 20041201
Title: p38 MAPK signaling pathway is involved in butyrate-induced vitamin D receptor expression.
Journal: Biochemical and biophysical research communications 20041126
Title: Resistin promotes smooth muscle cell proliferation through activation of extracellular signal-regulated kinase 1/2 and phosphatidylinositol 3-kinase pathways.
Journal: Circulation 20041123
Title: [Activation of HIF-1 by bFGF in breast cancer: role of PI-3K and MEK1/ERK pathways].
Journal: Zhonghua yi xue za zhi 20041117
Title: Transactivation of epidermal growth factor receptor mediates catecholamine-induced growth of vascular smooth muscle.
Journal: Circulation research 20041112
Title: Inhibition of the stress-activated kinase, p38, does not affect the virus transcriptional program of herpes simplex virus type 1.
Journal: Virology 20041110
Title: Role of mitogen-activated protein kinase activation in injured and intact primary afferent neurons for mechanical and heat hypersensitivity after spinal nerve ligation.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20041110
Title: Activation of endothelial nitric-oxide synthase by the p38 MAPK in response to black tea polyphenols.
Journal: The Journal of biological chemistry 20041105
Title: Bacterial endotoxin induces IL-20 expression in the glial cells.
Journal: Brain research. Molecular brain research 20041104
Title: Curcumin induces c-jun N-terminal kinase-dependent apoptosis in HCT116 human colon cancer cells.
Journal: Carcinogenesis 20041101
Title: Gialpha3 protein-coupled dopamine D3 receptor-mediated inhibition of renal NHE3 activity in SHR proximal tubular cells is a PLC-PKC-mediated event.
Journal: American journal of physiology. Renal physiology 20041101
Title: A novel series of p38 MAP kinase inhibitors for the potential treatment of rheumatoid arthritis.
Journal: Bioorganic & medicinal chemistry letters 20041101
Title: Novel, potent and selective anilinoquinazoline and anilinopyrimidine inhibitors of p38 MAP kinase.
Journal: Bioorganic & medicinal chemistry letters 20041101
Title: Phenylephrine induces activation of CREB in adult rat cardiac myocytes through MSK1 and PKA signaling pathways.
Journal: Journal of molecular and cellular cardiology 20041101
Title: Retinol binding protein isolated from acute renal failure patients inhibits polymorphonuclear leucocyte functions.
Journal: European journal of clinical investigation 20041101
Title: Hyperforin, the active component of St. John's wort, induces IL-8 expression in human intestinal epithelial cells via a MAPK-dependent, NF-kappaB-independent pathway.
Journal: Journal of clinical immunology 20041101
Title: The p38 MAPK inhibitor SB203580 blocks adenosine A(1) receptor-induced attenuation of in vivo myocardial stunning.
Journal: Cardiovascular drugs and therapy 20041101
Title: Endothelin-1 stimulates cyclooxygenase-2 expression in ovarian cancer cells through multiple signaling pathways: evidence for involvement of transactivation of the epidermal growth factor receptor.
Journal: Journal of cardiovascular pharmacology 20041101
Title: Asbestos induces tissue factor in Beas-2B cells via PI3 kinase-PKC-mediated signaling.
Journal: Journal of toxicology and environmental health. Part A 20041008
Title: Frontal affinity chromatography with MS detection of EphB2 tyrosine kinase receptor. 1. Comparison with conventional ELISA.
Journal: Journal of medicinal chemistry 20041007
Title: The development of new bicyclic pyrazole-based cytokine synthesis inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20041004
Title: Hypoxia-responsive growth factors upregulate periostin and osteopontin expression via distinct signaling pathways in rat pulmonary arterial smooth muscle cells.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20041001
Title: Cross-talk between phosphatidylinositol 3-kinase/AKT and c-jun NH2-terminal kinase mediates survival of isolated human islets.
Journal: Endocrinology 20041001
Title: An inhibitor of p38 MAP kinase downregulates cytokine release induced by sulfur mustard exposure in human epidermal keratinocytes.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20041001
Title: MAP kinases differentially regulate the expression of macrophage hyperactivity after thermal injury.
Journal: Journal of cellular physiology 20041001
Title: Inhibition of p38 MAP kinase- and RICK/NF-kappaB-signaling suppresses inflammatory bowel disease.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20041001
Title: Mechanical stimulation and mitogen-activated protein kinase signaling independently regulate osteogenic differentiation and mineralization by calcifying vascular cells.
Journal: Journal of biomechanics 20041001
Title: IL-1beta regulates expression of Cx32, occludin, and claudin-2 of rat hepatocytes via distinct signal transduction pathways.
Journal: Experimental cell research 20041001
Title: Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels.
Journal: Circulation research 20041001
Title: Je-chun-jun induced apoptosis of human cervical carcinoma HeLa cells.
Journal: Acta pharmacologica Sinica 20041001
Title: Identification of a novel mitogen-activated protein kinase in Toxoplasma gondii.
Journal: International journal for parasitology 20041001
Title: Suppression of plasma free fatty acids upregulates peroxisome proliferator-activated receptor (PPAR) alpha and delta and PPAR coactivator 1alpha in human skeletal muscle, but not lipid regulatory genes.
Journal: Journal of molecular endocrinology 20041001
Title: High sensitivity of fibroblast cell lines derived from LEC rats to heat treatment.
Journal: The Journal of veterinary medical science 20041001
Title: Promyelocytic leukemia is a direct inhibitor of SAPK2/p38 mitogen-activated protein kinase.
Journal: The Journal of biological chemistry 20040924
Title: Andrographolide acts through inhibition of ERK1/2 and Akt phosphorylation to suppress chemotactic migration.
Journal: European journal of pharmacology 20040913
Title: Phospholipase D isozymes mediate epigallocatechin gallate-induced cyclooxygenase-2 expression in astrocyte cells.
Journal: The Journal of biological chemistry 20040910
Title: Characterization of the bone morphogenetic protein (BMP) system in human pulmonary arterial smooth muscle cells isolated from a sporadic case of primary pulmonary hypertension: roles of BMP type IB receptor (activin receptor-like kinase-6) in the mitotic action.
Journal: Endocrinology 20040901
Title: cAMP-response element-binding protein mediates tumor necrosis factor-alpha-induced vascular smooth muscle cell migration.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20040901
Title: Different roles of ERK and p38 MAP kinases during tube formation from endothelial cells cultured in 3-dimensional collagen matrices.
Journal: Journal of cellular physiology 20040901
Title: Native LDL and oxidized LDL modulate cyclooxygenase-2 expression in HUVECs through a p38-MAPK, NF-kappaB, CRE dependent pathway and affect PGE2 synthesis.
Journal: International journal of molecular medicine 20040901
Title: Inhibition of human immunodeficiency virus type 1 replication by Z-100, an immunomodulator extracted from human-type tubercle bacilli, in macrophages.
Journal: The Journal of general virology 20040901
Title: Role of PDE4 in superoxide anion generation through p44/42MAPK regulation: a cAMP and a PKA-independent mechanism.
Journal: British journal of pharmacology 20040901
Title: Flavonoids inhibit tumor necrosis factor-alpha-induced up-regulation of intercellular adhesion molecule-1 (ICAM-1) in respiratory epithelial cells through activator protein-1 and nuclear factor-kappaB: structure-activity relationships.
Journal: Molecular pharmacology 20040901
Title: Glutathione depletion in CYP2E1-expressing liver cells induces toxicity due to the activation of p38 mitogen-activated protein kinase and reduction of nuclear factor-kappaB DNA binding activity.
Journal: Molecular pharmacology 20040901
Title: Role of mitogen-activated protein kinase in the regulation of transforming growth factor-beta-induced fibronectin accumulation in cultured renal interstitial fibroblasts.
Journal: Clinical and experimental nephrology 20040901
Title: Differential activation of Smads in HeLa and SiHa cells that differ in their response to transforming growth factor-beta.
Journal: The Journal of biological chemistry 20040827
Title: Hyperosmotically induced accumulation of a phosphorylated p38-like MAPK involved in protoplast volume regulation of plasmolyzed wheat root cells.
Journal: FEBS letters 20040827
Title: Glucose-potentiated chemotaxis in human vascular smooth muscle is dependent on cross-talk between the PI3K and MAPK signaling pathways.
Journal: Circulation research 20040820
Title: Vasopressin phosphorylates HSP27 in aortic smooth muscle cells.
Journal: Journal of cellular biochemistry 20040815
Title: p21(Cip-1/SDI-1/WAF-1) expression via the mitogen-activated protein kinase signaling pathway in insulin-induced chondrogenic differentiation of ATDC5 cells.
Journal: Biochemical and biophysical research communications 20040806
Title: Involvement of mitogen-activated protein kinases and protein kinase C in cadmium-induced prostaglandin E2 production in primary mouse osteoblastic cells.
Journal: Toxicology 20040805
Title: Inhibition of phosphatidylinostol 3-kinase uncouples H2O2-induced senescent phenotype and cell cycle arrest in normal human diploid fibroblasts.
Journal: Experimental cell research 20040801
Title: A new role for BMP5 during limb development acting through the synergic activation of Smad and MAPK pathways.
Journal: Developmental biology 20040801
Title: Contribution of the p38MAPK signalling pathway to proliferation in human cultured airway smooth muscle cells is mitogen-specific.
Journal: British journal of pharmacology 20040801
Title: Responses of neutrophils to anti-integrin antibodies depends on costimulation through low affinity Fc gamma Rs: full activation requires both integrin and nonintegrin signals.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20040801
Title: Interleukin-4 increases murine airway response to kinins, via up-regulation of bradykinin B1-receptors and altered signalling along mitogen-activated protein kinase pathways.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040801
Title: LDL oxidized by hypochlorous acid causes irreversible platelet aggregation when combined with low levels of ADP, thrombin, epinephrine, or macrophage-derived chemokine (CCL22).
Journal: Blood 20040715
Title: Induction of matrix metalloproteinase-2 by tenascin-X deficiency is mediated through the c-Jun N-terminal kinase and protein tyrosine kinase phosphorylation pathway.
Journal: Experimental cell research 20040715
Title: Mood stabilizers inhibit glucocorticoid receptor function in LMCAT cells.
Journal: European journal of pharmacology 20040714
Title: Interleukin-8 production by THP-1 cells stimulated by Salmonella enterica serovar Typhimurium porins is mediated by AP-1, NF-kappaB and MAPK pathways.
Journal: Cytokine 20040707
Title: Activation of Ca2+/calmodulin-dependent protein kinase II is involved in hyperosmotic induction of the human taurine transporter.
Journal: FEBS letters 20040702
Title: Interferon-tau induces degradation of prostaglandin H synthase-2 messenger RNA in bovine endometrial cells through a transcription-dependent mechanism.
Journal: Biology of reproduction 20040701
Title: Hepatitis B viral HBx induces matrix metalloproteinase-9 gene expression through activation of ERK and PI-3K/AKT pathways: involvement of invasive potential.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040701
Title: Differential regulation of mast cell cytokines by both dexamethasone and the p38 mitogen-activated protein kinase (MAPK) inhibitor SB203580.
Journal: Clinical and experimental immunology 20040701
Title: C-jun N-terminal kinase modulates 1,25-dihydroxyvitamin D3-induced cytochrome P450 3A4 gene expression.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20040701
Title: Regulation of metalloproteinases and NF-kappaB activation in rabbit synovial fibroblasts via E prostaglandins and Erk: contrasting effects of nabumetone and 6MNA.
Journal: British journal of pharmacology 20040701
Title: Correlation of MAP kinases with COX-2 induction differs between MKN45 and HT29 cells.
Journal: Alimentary pharmacology & therapeutics 20040701
Title: Receptor activator of nuclear factor-kappaB is induced by a rottlerin-sensitive and p38 MAP kinase-dependent pathway during monocyte differentiation.
Journal: Molecules and cells 20040630
Title: Distinct ligand-dependent roles for p38 MAPK in priming and activation of the neutrophil NADPH oxidase.
Journal: The Journal of biological chemistry 20040625
Title: Streptozotocin directly impairs cardiac contractile function in isolated ventricular myocytes via a p38 map kinase-dependent oxidative stress mechanism.
Journal: Biochemical and biophysical research communications 20040611
Title: Novel expression of N-cadherin elicits in vitro bladder cell invasion via the Akt signaling pathway.
Journal: Oncogene 20040610
Title: Signaling pathways involved in induction of GADD45 gene expression and apoptosis by troglitazone in human MCF-7 breast carcinoma cells.
Journal: Oncogene 20040603
Title: Induction of manganese-superoxide dismutase by YS 51, a synthetic 1-(beta-naphtylmethyl)6,7-dihydroxy- 1,2,3,4-tetrahydroisoquinoline alkaloid: implication for anti-inflammatory actions.
Journal: Pharmacology 20040601
Title: NMDA and AMPA receptor expression and cortical neuronal death are associated with p38 in glutamate-induced excitotoxicity in vivo.
Journal: Journal of neuroscience research 20040601
Title: Angiotensin II increases Pax-2 expression in fetal kidney cells via the AT2 receptor.
Journal: Journal of the American Society of Nephrology : JASN 20040601
Title: Transient glucose deprivation causes upregulation of heme oxygenase-1 and cyclooxygenase-2 expression in cardiac fibroblasts.
Journal: Journal of molecular and cellular cardiology 20040601
Title: Type II gonadotropin-releasing hormone stimulates p38 mitogen-activated protein kinase and apoptosis in ovarian cancer cells.
Journal: The Journal of clinical endocrinology and metabolism 20040601
Title: Involvement of SAPK/JNK in prostaglandin E(1)-induced VEGF synthesis in osteoblast-like cells.
Journal: Molecular and cellular endocrinology 20040531
Title: Regulation of the circadian oscillator in Xenopus retinal photoreceptors by protein kinases sensitive to the stress-activated protein kinase inhibitor, SB 203580.
Journal: The Journal of biological chemistry 20040521
Title: NF-kappaB activation mechanism of 4-hydroxyhexenal via NIK/IKK and p38 MAPK pathway.
Journal: FEBS letters 20040521
Title: Staphylococcus aureus peptidoglycan stimulates granulocyte macrophage colony-stimulating factor production from human epidermal keratinocytes via mitogen-activated protein kinases.
Journal: FEBS letters 20040521
Title: Development of orally bioavailable bicyclic pyrazolones as inhibitors of tumor necrosis factor-alpha production.
Journal: Journal of medicinal chemistry 20040520
Title: Stress- and mitogen-induced phosphorylation of the synapse-associated protein SAP90/PSD-95 by activation of SAPK3/p38gamma and ERK1/ERK2.
Journal: The Biochemical journal 20040515
Title: Inhibition of delayed induction of p38 mitogen-activated protein kinase attenuates kainic acid-induced neuronal loss in the hippocampus.
Journal: Brain research 20040508
Title: Angiotensin II differentially regulates interleukin-1-beta-inducible NO synthase (iNOS) and vascular cell adhesion molecule-1 (VCAM-1) expression: role of p38 MAPK.
Journal: The Journal of biological chemistry 20040507
Title: Regulation of macrophage cyclooxygenase-2 gene expression by modifications of histone H3.
Journal: American journal of physiology. Lung cellular and molecular physiology 20040501
Title: p38 mitogen-activated protein kinase contributes to the diminished aortic contraction by endothelin-1 in DOCA-salt hypertensive rats.
Journal: Hypertension (Dallas, Tex. : 1979) 20040501
Title: Possible involvement of p38 MAP kinase in prostaglandin E1-induced ALP activity in osteoblast-like cells.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20040501
Title: The hierarchical relationship between MAPK signaling and ROS generation in human leukemia cells undergoing apoptosis in response to the proteasome inhibitor Bortezomib.
Journal: Experimental cell research 20040501
Title: Isoflurane preconditioning induces neuroprotection against ischemia via activation of P38 mitogen-activated protein kinases.
Journal: Molecular pharmacology 20040501
Title: Restoration of impaired p38 activation by insulin in insulin resistant skeletal muscle cells treated with thiazolidinediones.
Journal: Molecular and cellular biochemistry 20040501
Title: Various stressors rapidly activate the p38-MAPK signaling pathway in Mytilus galloprovincialis (Lam.).
Journal: Molecular and cellular biochemistry 20040501
Title: Endothelial dysfunction and altered bradykinin response due to oxidative stress induced by serum deprivation in the bovine cerebral artery.
Journal: European journal of pharmacology 20040426
Title: Bcl-xL and E1B-19K proteins inhibit p53-induced irreversible growth arrest and senescence by preventing reactive oxygen species-dependent p38 activation.
Journal: The Journal of biological chemistry 20040423
Title: Mechanism of glutamine-mediated amelioration of lipopolysaccharide-induced IL-8 production in Caco-2 cells.
Journal: Cytokine 20040421
Title: Anisomycin downregulates gap-junctional intercellular communication via the p38 MAP-kinase pathway.
Journal: Journal of cell science 20040415
Title: Transcription factor Sp1 mediates p38MAPK-dependent activation of the p21WAF1 gene promoter in vascular smooth muscle cells by pyrrolidine dithiocarbamate.
Journal: Biochemical and biophysical research communications 20040409
Title: A requirement of MAPKAPK2 in the uropod localization of PTEN during FMLP-induced neutrophil chemotaxis.
Journal: Biochemical and biophysical research communications 20040409
Title: Identification of proteins differentially expressed during chondrogenesis of mesenchymal cells.
Journal: FEBS letters 20040409
Title: Human lung fibroblasts express interleukin-6 in response to signaling after mast cell contact.
Journal: American journal of respiratory cell and molecular biology 20040401
Title: Activation of p38 MAP kinase by asbestos in rat mesothelial cells is mediated by oxidative stress.
Journal: American journal of physiology. Lung cellular and molecular physiology 20040401
Title: Identification of glycogen synthase as a new substrate for stress-activated protein kinase 2b/p38beta.
Journal: The Biochemical journal 20040401
Title: Fine particulate matter induces amphiregulin secretion by bronchial epithelial cells.
Journal: American journal of respiratory cell and molecular biology 20040401
Title: Involvement of ERK AND p38 MAP kinase in AAPH-induced COX-2 expression in HaCaT cells.
Journal: Chemistry and physics of lipids 20040401
Title: A critical 'threshold' of beta 2-integrin engagement regulates augmentation of cytokine-mediated superoxide anion release.
Journal: British journal of pharmacology 20040401
Title: Sgk1 mediates osmotic induction of NPR-A gene in rat inner medullary collecting duct cells.
Journal: Hypertension (Dallas, Tex. : 1979) 20040401
Title: Native LDL induces interleukin-8 expression via H2O2, p38 Kinase, and activator protein-1 in human aortic smooth muscle cells.
Journal: Cardiovascular research 20040401
Title: Superinduction of IL-6 by cycloheximide is associated with mRNA stabilization and sustained activation of p38 map kinase and NF-kappaB in cultured caco-2 cells.
Journal: Journal of cellular biochemistry 20040401
Title: Interleukin (IL)-17 enhances tumor necrosis factor-alpha-stimulated IL-6 synthesis via p38 mitogen-activated protein kinase in osteoblasts.
Journal: Journal of cellular biochemistry 20040401
Title: Mercury-induced apoptosis and necrosis in murine macrophages: role of calcium-induced reactive oxygen species and p38 mitogen-activated protein kinase signaling.
Journal: Toxicology and applied pharmacology 20040401
Title: Smad7 is required for TGF-beta-induced activation of the small GTPase Cdc42.
Journal: Journal of cell science 20040401
Title: Mechanism of human urotensin II-induced contraction in rat aorta.
Journal: Journal of pharmacological sciences 20040401
Title: Cell survival signalling in heart derived myofibroblasts induced by preconditioning and bradykinin: the role of p38 MAP kinase.
Journal: Molecular and cellular biochemistry 20040401
Title: [Effects of mitogen activated protein kinase signal transduction pathways on heat shock protein 70 gene expression in endothelial cells exposed to benzo(a)pryene].
Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20040401
Title: [Effects of P2Y receptor activation on prostatic cancer cells requiring ERK1/2 or p38 cascade].
Journal: Zhonghua bing li xue za zhi = Chinese journal of pathology 20040401
Title: RanBPM is a phosphoprotein that associates with the plasma membrane and interacts with the integrin LFA-1.
Journal: The Journal of biological chemistry 20040326
Title: Involvement of p38 mitogen-activated protein kinase in gemcitabine-induced apoptosis in human pancreatic cancer cells.
Journal: Biochemical and biophysical research communications 20040326
Title: Suppression of HIV-1 viral replication and cellular pathogenesis by a novel p38/JNK kinase inhibitor.
Journal: AIDS (London, England) 20040326
Title: Overexpression of aldehyde dehydrogenase-2 (ALDH2) transgene prevents acetaldehyde-induced cell injury in human umbilical vein endothelial cells: role of ERK and p38 mitogen-activated protein kinase.
Journal: The Journal of biological chemistry 20040319
Title: Calcineurin promotes the expression of monocyte chemoattractant protein-1 in vascular myocytes and mediates vascular inflammation.
Journal: Circulation research 20040319
Title: A late, prolonged activation of the phosphatidylinositol 3-kinase pathway is required for T cell proliferation.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20040315
Title: Mitogen-activated protein kinase modulation of nuclear factor-kappaB-induced granulocyte macrophage-colony-stimulating factor release from human alveolar macrophages.
Journal: American journal of respiratory cell and molecular biology 20040301
Title: Platelet factor 4 (PF-4)-induced neutrophil adhesion is controlled by src-kinases, whereas PF-4-mediated exocytosis requires the additional activation of p38 MAP kinase and phosphatidylinositol 3-kinase.
Journal: Blood 20040301
Title: Protein kinase C alpha requirement in the activation of p38 mitogen-activated protein kinase, which is linked to the induction of tumor necrosis factor alpha in lipopolysaccharide-stimulated microglia.
Journal: Neurochemistry international 20040301
Title: Tamoxifen inhibits cell proliferation via mitogen-activated protein kinase cascades in human ovarian cancer cell lines in a manner not dependent on the expression of estrogen receptor or the sensitivity to cisplatin.
Journal: Endocrinology 20040301
Title: A p38 inhibitor allows to dissociate differentiation and apoptotic processes triggered upon LIF withdrawal in mouse embryonic stem cells.
Journal: Cell death and differentiation 20040301
Title: Pharmacological inhibition of Mannheimia haemolytica lipopolysaccharide and leukotoxin-induced cytokine expression in bovine alveolar macrophages.
Journal: Microbial pathogenesis 20040301
Title: Insulin enhances vascular cell adhesion molecule-1 expression in human cultured endothelial cells through a pro-atherogenic pathway mediated by p38 mitogen-activated protein-kinase.
Journal: Diabetologia 20040301
Title: Examination of the signal transduction pathways involved in matrix metalloproteinases-2 in human pulp cells.
Journal: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20040301
Title: Reciprocal regulation of beta-adrenergic receptor mRNA stability by mitogen activated protein kinase activation and inhibition.
Journal: Molecular and cellular biochemistry 20040301
Title: Possible involvement of p38 in mechanisms underlying acceleration of proliferation by 15-deoxy-Delta(12,14)-prostaglandin J2 and the precursors in leukemia cell line THP-1.
Journal: Journal of pharmacological sciences 20040301
Title: Mechanisms of the influence of magnolol on eicosanoid metabolism in neutrophils.
Journal: Biochemical pharmacology 20040301
Title: Benzimidazolone p38 inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20040223
Title: Expression of adhesion molecules by sphingosine 1-phosphate and histamine in endothelial cells.
Journal: European journal of pharmacology 20040220
Title: Homeodomain-interacting protein kinase-2 activity and p53 phosphorylation are critical events for cisplatin-mediated apoptosis.
Journal: Experimental cell research 20040215
Title: Distinctive regulation and function of PI 3K/Akt and MAPKs in doxorubicin-induced apoptosis of human lung adenocarcinoma cells.
Journal: Journal of cellular biochemistry 20040215
Title: Novel regulatory mechanisms of CD40-induced prostanoid synthesis by IL-4 and IL-10 in human monocytes.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20040215
Title: Delayed preconditioning of the human myocardium: signal transduction and clinical implications.
Journal: Cardiovascular research 20040215
Title: Endothelin-1 promotes phosphorylation of CREB transcription factor in primary cultures of neonatal rat cardiac myocytes: implications for the regulation of c-jun expression.
Journal: Biochimica et biophysica acta 20040202
Title: Copper-inducible transcription: regulation by metal- and oxidative stress-responsive pathways.
Journal: American journal of physiology. Cell physiology 20040201
Title: PDTC, metal chelating compound, induces G1 phase cell cycle arrest in vascular smooth muscle cells through inducing p21Cip1 expression: involvement of p38 mitogen activated protein kinase.
Journal: Journal of cellular physiology 20040201
Title: Molecular mechanism of nucleotide-induced primary granule release in human neutrophils: role for the P2Y2 receptor.
Journal: American journal of physiology. Cell physiology 20040201
Title: Calcium pyrophosphate dihydrate crystal associated induction of neutrophil activation and repression of TNF-alpha-induced apoptosis is mediated by the p38 MAP kinase.
Journal: Cellular signalling 20040201
Title: A Biacore biosensor method for detailed kinetic binding analysis of small molecule inhibitors of p38alpha mitogen-activated protein kinase.
Journal: Analytical biochemistry 20040201
Title: Selenium attenuates lipopolysaccharide-induced oxidative stress responses through modulation of p38 MAPK and NF-kappaB signaling pathways.
Journal: Experimental biology and medicine (Maywood, N.J.) 20040201
Title: Aspirin-mediated COX-2 transcript stabilization via sustained p38 activation in human intestinal myofibroblasts.
Journal: Molecular pharmacology 20040201
Title: Suppression by p38 MAP kinase inhibitors (pyridinyl imidazole compounds) of Ah receptor target gene activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin and the possible mechanism.
Journal: The Journal of biological chemistry 20040130
Title: 12-O-tetradecanoylphorbol-13-acetate may both potentiate and decrease the generation of apoptosis by the antileukemic agent arsenic trioxide in human promonocytic cells. Regulation by extracellular signal-regulated protein kinases and glutathione.
Journal: The Journal of biological chemistry 20040130
Title: Upregulation of heme oxygenase-1 and p21 confers resistance to apoptosis in human gastric cancer cells.
Journal: Oncogene 20040115
Title: Involvement of p38 and p42/44 MAP kinases and protein kinase C in the interferon-gamma and interleukin-1alpha-induced phosphorylation of 85-kDa cytosolic phospholipase A(2) in primary human bronchial epithelial cells.
Journal: Cytokine 20040107
Title: Actin reorganization and morphological changes in human neutrophils stimulated by TNF, GM-CSF, and G-CSF: the role of MAP kinases.
Journal: American journal of physiology. Cell physiology 20040101
Title: A role for p38 MAP kinase in platelet activation by von Willebrand factor.
Journal: Thrombosis and haemostasis 20040101
Title: Novel form of LTD induced by transient, partial inhibition of the Na,K-pump in rat hippocampal CA1 cells.
Journal: Journal of neurophysiology 20040101
Title: Arginase induction promotes Trypanosoma cruzi intracellular replication in Cruzipain-treated J774 cells through the activation of multiple signaling pathways.
Journal: European journal of immunology 20040101
Title: Co-treatment with dexamethasone and octanoate induces adipogenesis in 3T3-L1 cells.
Journal: Cell biology international 20040101
Title: Inhibition of cardiac myocyte contraction by 4-hydroxy-trans-2-nonenal.
Journal: Cardiovascular toxicology 20040101
Title: HERG K channel conductance promotes H2O2-induced apoptosis in HEK293 cells: cellular mechanisms.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20040101
Title: Cytochalasin B triggers a novel pertussis toxin sensitive pathway in TNF-alpha primed neutrophils.
Journal: BMC cell biology 20040101
Title: Characterization of Cd-induced molecular events prior to cellular damage in primary rat hepatocytes in culture: activation of the stress activated signal protein JNK and transcription factor AP-1.
Journal: Journal of biochemical and molecular toxicology 20040101
Title: MAP kinase activation by fluoxetine and its relation to gene expression in cultured rat astrocytes.
Journal: Journal of molecular neuroscience : MN 20040101
Title: The oxygen radical generator pyrogallol impairs cardiomyocyte contractile function via a superoxide and p38 MAP kinase-dependent pathway: protection by anisodamine and tetramethylpyrazine.
Journal: Cardiovascular toxicology 20040101
Title: Dysferlin in a hyperCKaemic patient with caveolin 3 mutation and in C2C12 cells after p38 MAP kinase inhibition.
Journal: Experimental & molecular medicine 20031231
Title: p38 MAP kinase mediates bilirubin-induced neuronal death of cultured rat cerebellar granule neurons.
Journal: Neuroscience letters 20031226
Title: Involvement of tumor suppressor protein p53 and p38 MAPK in caffeic acid phenethyl ester-induced apoptosis of C6 glioma cells.
Journal: Biochemical pharmacology 20031215
Title: Successful shape-based virtual screening: the discovery of a potent inhibitor of the type I TGFbeta receptor kinase (TbetaRI).
Journal: Bioorganic & medicinal chemistry letters 20031215
Title: Phorbol ester stimulates the nonhypoxic induction of a novel hypoxia-inducible factor 1alpha isoform: implications for tumor promotion.
Journal: Cancer research 20031215
Title: Cadmium induces nuclear export of Bach1, a transcriptional repressor of heme oxygenase-1 gene.
Journal: The Journal of biological chemistry 20031205
Title: Phenotypic switching of VEGF and collagen XVIII during hypoxia in head and neck squamous carcinoma cells.
Journal: Oral oncology 20031201
Title: Tumor necrosis factor-alpha and troglitazone regulate plasminogen activator inhibitor type 1 production through extracellular signal-regulated kinase- and nuclear factor-kappaB-dependent pathways in cultured human umbilical vein endothelial cells.
Journal: The Journal of pharmacology and experimental therapeutics 20031201
Title: Formyl-Met-Leu-Phe induces calcium-dependent tyrosine phosphorylation of Rel-1 in neutrophils.
Journal: Cell calcium 20031201
Title: IGF-I stimulates IL-8 production in the promyelocytic cell line HL-60 through activation of extracellular signal-regulated protein kinase.
Journal: Cellular signalling 20031201
Title: Redox regulation of reactive oxygen species-induced p38 MAP kinase activation and barrier dysfunction in lung microvascular endothelial cells.
Journal: Antioxidants & redox signaling 20031201
Title: Verotoxin activates mitogen-activated protein kinase in human peripheral blood monocytes: role in apoptosis and proinflammatory cytokine release.
Journal: British journal of pharmacology 20031201
Title: Calphostin C as a rapid and strong inducer of apoptosis in human coronary artery smooth muscle cells.
Journal: International immunopharmacology 20031201
Title: Transcriptional and posttranscriptional roles for p38 mitogen-activated protein kinase in upregulation of TNF-alpha expression by deoxynivalenol (vomitoxin).
Journal: Toxicology and applied pharmacology 20031201
Title: Vitamin C downregulates interleukin-18 production by increasing reactive oxygen intermediate and mitogen-activated protein kinase signalling in B16F10 murine melanoma cells.
Journal: Melanoma research 20031201
Title: Dexamethasone-induced and estradiol-induced CREB activation and annexin 1 expression in CCRF-CEM lymphoblastic cells: evidence for the involvement of cAMP and p38 MAPK.
Journal: Mediators of inflammation 20031201
Title: Effect of MG132, a proteasome inhibitor, on the expression of growth related oncogene protein-alpha in human umbilical vein endothelial cells.
Journal: Cytokine 20031107
Title: Are changes in MAPK/ERK necessary or sufficient for entrainment in chick pineal cells?
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20031105
Title: Feedback control of the protein kinase TAK1 by SAPK2a/p38alpha.
Journal: The EMBO journal 20031103
Title: ANP inhibits TNF-alpha-induced endothelial MCP-1 expression--involvement of p38 MAPK and MKP-1.
Journal: Journal of leukocyte biology 20031101
Title: MAPK-activated protein kinase-2 participates in p38 MAPK-dependent and ERK-dependent functions in human neutrophils.
Journal: Cellular signalling 20031101
Title: Parathyroid hormone-related protein induces insulin expression through activation of MAP kinase-specific phosphatase-1 that dephosphorylates c-Jun NH2-terminal kinase in pancreatic beta-cells.
Journal: Diabetes 20031101
Title: Induction of protein synthesis in cardiac fibroblasts by cardiotrophin-1: integration of multiple signaling pathways.
Journal: Cardiovascular research 20031101
Title: Tamoxifen induces vasorelaxation via inhibition of mitogen-activated protein kinase in rat aortic smooth muscle.
Journal: The Journal of veterinary medical science 20031101
Title: The 2G single nucleotide polymorphism (SNP) in the MMP-1 promoter contributes to high levels of MMP-1 transcription in MCF-7/ADR breast cancer cells.
Journal: Breast cancer research and treatment 20031101
Title: A requirement for calcium-independent phospholipase A2 in thrombin-induced arachidonic acid release and growth in vascular smooth muscle cells.
Journal: The Journal of biological chemistry 20031031
Title: Cellular redistribution of inducible Hsp70 protein in the human and rabbit heart in response to the stress of chronic hypoxia: role of protein kinases,
Journal: The Journal of biological chemistry 20031031
Title: Structure-activity relationships of the p38alpha MAP kinase inhibitor 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)naph- thalen-1-yl]urea (BIRB 796).
Journal: Journal of medicinal chemistry 20031023
Title: Effect of sesame antioxidants on LPS-induced NO production by BV2 microglial cells.
Journal: Neuroreport 20031006
Title: Intraluminal pressure stimulates MAPK phosphorylation in arterioles: temporal dissociation from myogenic contractile response.
Journal: American journal of physiology. Heart and circulatory physiology 20031001
Title: Adenosine-induced IL-6 expression in pituitary folliculostellate cells is mediated via A2b adenosine receptors coupled to PKC and p38 MAPK.
Journal: British journal of pharmacology 20031001
Title: Vasodilative effects of urocortin II via protein kinase A and a mitogen-activated protein kinase in rat thoracic aorta.
Journal: Journal of cardiovascular pharmacology 20031001
Title: Arsenite stimulated glucose transport in 3T3-L1 adipocytes involves both Glut4 translocation and p38 MAPK activity.
Journal: European journal of biochemistry 20031001
Title: Insulin resistance induces hyperleptinemia, cardiac contractile dysfunction but not cardiac leptin resistance in ventricular myocytes.
Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20031001
Title: Growth hormone reduces chloride secretion in human colonic epithelial cells via EGF receptor and extracellular regulated kinase.
Journal: Gastroenterology 20031001
Title: Difference in signal transduction mechanisms involved in 5-hydroxytryptamine- and U46619-induced vasoconstrictions.
Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20031001
Title: Butyric acid sensitizes Vero cells to ricin-induced apoptosis via accelerated activation of multiple signal transduction pathways.
Journal: Cell structure and function 20031001
Title: Phosphatidylinositol 3-kinase in angiotensin II-induced hypertrophy of vascular smooth muscle cells.
Journal: European journal of pharmacology 20030930
Title: Reactive oxygen species sensitivity of angiotensin II-dependent translation initiation in vascular smooth muscle cells.
Journal: The Journal of biological chemistry 20030919
Title: A regulatory role for p38 delta MAPK in keratinocyte differentiation. Evidence for p38 delta-ERK1/2 complex formation.
Journal: The Journal of biological chemistry 20030905
Title: Air pollution particles produce airway wall remodeling in rat tracheal explants.
Journal: American journal of respiratory cell and molecular biology 20030901
Title: The cytoplasmic domain of Alzheimer's amyloid-beta protein precursor causes sustained apoptosis signal-regulating kinase 1/c-Jun NH2-terminal kinase-mediated neurotoxic signal via dimerization.
Journal: The Journal of pharmacology and experimental therapeutics 20030901
Title: Regulation of toll-like receptor 2 and 4 gene expression in murine alveolar macrophages.
Journal: Experimental lung research 20030901
Title: Structural basis for p38alpha MAP kinase quinazolinone and pyridol-pyrimidine inhibitor specificity.
Journal: Nature structural biology 20030901
Title: Lipopolysaccharide-induced dopaminergic cell death in rat midbrain slice cultures: role of inducible nitric oxide synthase and protection by indomethacin.
Journal: Journal of neurochemistry 20030901
Title: Induction of RANTES/CCL5 by herpes simplex virus is regulated by nuclear factor kappa B and interferon regulatory factor 3.
Journal: The Journal of general virology 20030901
Title: Role of p38 mitogen-activated protein kinase in Kupffer cell secretion of the proinflammatory cytokines after burn trauma.
Journal: Burns : journal of the International Society for Burn Injuries 20030901
Title: Inhibition of the stem cell factor-induced migration of mast cells by dexamethasone.
Journal: Endocrinology 20030901
Title: Staurosporine induces rapid homotypic intercellular adhesion of U937 cells via multiple kinase activation.
Journal: British journal of pharmacology 20030901
Title: Hypertrophic agonists induce the binding of c-Fos to an AP-1 site in cardiac myocytes: implications for the expression of GLUT1.
Journal: Cardiovascular research 20030901
Title: Sphingosine-1-phosphate-induced ERK activation protects human melanocytes from UVB-induced apoptosis.
Journal: Archives of pharmacal research 20030901
Title: Platelet-derived growth factor-BB stimulated cell migration mediated through p38 signal transduction pathway in periodontal cells.
Journal: Journal of periodontology 20030901
Title: Induction of apoptosis of RAW 264.7 cells by the cytostatic macrolide apicularen A.
Journal: The Journal of pharmacy and pharmacology 20030901
Title: TRAIL activates a caspase 9/7-dependent pathway in caspase 8/10-defective SK-N-SH neuroblastoma cells with two functional end points: induction of apoptosis and PGE2 release.
Journal: Neoplasia (New York, N.Y.) 20030901
Title: Induction of glia maturation factor-beta in proximal tubular cells leads to vulnerability to oxidative injury through the p38 pathway and changes in antioxidant enzyme activities.
Journal: The Journal of biological chemistry 20030829
Title: The PI 3-kinase-Rac-p38 MAP kinase pathway is involved in the formation of signet-ring cell carcinoma.
Journal: Oncogene 20030828
Title: Homocysteine mediated expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human monocytes.
Journal: Circulation research 20030822
Title: Administration of the p38 MAPK inhibitor SB203580 affords brain protection with a wide therapeutic window against focal ischemic insult.
Journal: Journal of neuroscience research 20030815
Title: SP600125, an inhibitor of c-jun N-terminal kinase, activates CREB by a p38 MAPK-mediated pathway.
Journal: Biochemical and biophysical research communications 20030808
Title: Regulatory volume increase is associated with p38 kinase-dependent actin cytoskeleton remodeling in rat kidney MTAL.
Journal: American journal of physiology. Renal physiology 20030801
Title: Phosphorylation of initiation factor 4E is resistant to SB203580 in cells expressing a drug-resistant mutant of stress-activated protein kinase 2a/p38.
Journal: Cellular signalling 20030801
Title: Eicosapentaenoic acid inhibits PDGF-induced mitogenesis and cyclin D1 expression via TGF-beta in mesangial cells.
Journal: Journal of cellular physiology 20030801
Title: Inhibition of a p38/stress-activated protein kinase-2-dependent phosphatase restores function of IL-1 receptor-associate kinase-1 and reverses Toll-like receptor 2- and 4-dependent tolerance of macrophages.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030801
Title: Pancreatic stellate cell activation by ethanol and acetaldehyde: is it mediated by the mitogen-activated protein kinase signaling pathway?
Journal: Pancreas 20030801
Title: Malondialdehyde inhibits cardiac contractile function in ventricular myocytes via a p38 mitogen-activated protein kinase-dependent mechanism.
Journal: British journal of pharmacology 20030801
Title: [Role of p38 pathway in PMA-induced in vitro invasion of JAR human choriocarcinoma cell line].
Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20030801
Title: beta1-integrin-ligand disengagement induces in vitro capillary tube disruption mediated by p38 MAPK activity.
Journal: Surgery 20030801
Title: Cardiopulmonary bypass reduces peripheral microvascular contractile function by inhibition of mitogen-activated protein kinase activity.
Journal: Surgery 20030801
Title: Novel substituted pyridinyl imidazoles as potent anticytokine agents with low activity against hepatic cytochrome P450 enzymes.
Journal: Journal of medicinal chemistry 20030717
Title: c-Jun N-terminal kinase negatively regulates lipopolysaccharide-induced IL-12 production in human macrophages: role of mitogen-activated protein kinase in glutathione redox regulation of IL-12 production.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030715
Title: p38 mitogen-activated protein kinase regulates oscillation of chick pineal circadian clock.
Journal: The Journal of biological chemistry 20030704
Title: p38 MAPK inhibition is critically involved in VEGFR-2-mediated endothelial cell survival.
Journal: Biochemical and biophysical research communications 20030704
Title: Interleukin-3, -5, and granulocyte macrophage colony-stimulating factor-induced adhesion molecule expression on eosinophils by p38 mitogen-activated protein kinase and nuclear factor-[kappa] B.
Journal: American journal of respiratory cell and molecular biology 20030701
Title: Effects of transforming growth factor-[beta] and budesonide on mitogen-activated protein kinase activation and apoptosis in airway epithelial cells.
Journal: American journal of respiratory cell and molecular biology 20030701
Title: MAPK mediates PKC-dependent contraction of cat esophageal and lower esophageal sphincter circular smooth muscle.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20030701
Title: Mechanism of simvastatin on induction of heat shock protein in osteoblasts.
Journal: Archives of biochemistry and biophysics 20030701
Title: Involvement of MAP kinases in TGF-beta-stimulated vascular endothelial growth factor synthesis in osteoblasts.
Journal: Archives of biochemistry and biophysics 20030701
Title: Activation of protein kinase C delta by IFN-gamma.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030701
Title: Chronic regulation of the expression of the gap junction protein connexin 43 in transfected HeLa cells.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20030701
Title: Involvement of p38 MAPK, JNK, p42/p44 ERK and NF-kappaB in IL-1beta-induced chemokine release in human airway smooth muscle cells.
Journal: Respiratory medicine 20030701
Title: Clinically relevant hypertonicity prevents stored blood- and lipid-mediated delayed neutrophil apoptosis independent of p38 MAPK or caspase-3 activation.
Journal: Surgery 20030701
Title: Evidence that nitroprusside stimulates glucose uptake in isolated rat cardiomyocytes via mitogen-activated protein kinase.
Journal: Archives of physiology and biochemistry 20030701
Title: Role of the p38 MAPK pathway in cisplatin-based therapy.
Journal: Oncogene 20030626
Title: [Advanced glycation end products stimulate human endothelial cells to produce monocyte chemoattractant protein-1].
Journal: Zhonghua yi xue za zhi 20030625
Title: The regulation of inducible nitric oxide synthase gene expression induced by lipopolysaccharide and tumor necrosis factor-alpha in C6 cells: involvement of AP-1 and NFkappaB.
Journal: Life sciences 20030620
Title: Mechanisms of endotoxin tolerance in human intestinal microvascular endothelial cells.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030615
Title: Differential regulation of lipopolysaccharide-induced monocyte matrix metalloproteinase (MMP)-1 and MMP-9 by p38 and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030615
Title: Translation inhibitors sensitize prostate cancer cells to apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by activating c-Jun N-terminal kinase.
Journal: The Journal of biological chemistry 20030606
Title: p38 MAP kinase negatively regulates angiotensin II-mediated effects on cell cycle molecules in human coronary smooth muscle cells.
Journal: Biochemical and biophysical research communications 20030606
Title: Role of MAPK pathways in light chain-induced cytokine production in human proximal tubule cells.
Journal: American journal of physiology. Renal physiology 20030601
Title: Double-stranded RNA induces the synthesis of specific chemokines by bronchial epithelial cells.
Journal: American journal of respiratory cell and molecular biology 20030601
Title: p38 MAP kinase regulates BMP-4-stimulated VEGF synthesis via p70 S6 kinase in osteoblasts.
Journal: American journal of physiology. Endocrinology and metabolism 20030601
Title: Red wine polyphenolic compounds inhibit vascular endothelial growth factor expression in vascular smooth muscle cells by preventing the activation of the p38 mitogen-activated protein kinase pathway.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20030601
Title: Urocortin-related peptides increase interleukin-6 output via cyclic adenosine 5'-monophosphate-dependent pathways in A7r5 aortic smooth muscle cells.
Journal: Endocrinology 20030601
Title: Synergistic effect of TNF-alpha in soluble VCAM-1-induced angiogenesis through alpha 4 integrins.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030601
Title: C-Jun-NH2-terminal kinase mediates expression of connective tissue growth factor induced by transforming growth factor-beta1 in human lung fibroblasts.
Journal: American journal of respiratory cell and molecular biology 20030601
Title: Secretion of matrix metalloproteinase-9 by the proinflammatory cytokine, IL-1beta: a role for the dual signalling pathways, Akt and Erk.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20030601
Title: Endocannabinoids protect the rat isolated heart against ischaemia.
Journal: British journal of pharmacology 20030601
Title: Activation of p38 plays a pivotal role in the inhibitory effect of lipopolysaccharide and interleukin-1 beta on long term potentiation in rat dentate gyrus.
Journal: The Journal of biological chemistry 20030523
Title: Induction of heme oxygenase-1 expression in murine macrophages is essential for the anti-inflammatory effect of low dose 15-deoxy-Delta 12,14-prostaglandin J2.
Journal: The Journal of biological chemistry 20030523
Title: The development of new triazole based inhibitors of tumor necrosis factor-alpha (TNF-alpha) production.
Journal: Bioorganic & medicinal chemistry letters 20030519
Title: Selective roles for Toll-like receptor (TLR)2 and TLR4 in the regulation of neutrophil activation and life span.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030515
Title: p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030515
Title: Vanadium-induced HB-EGF expression in human lung fibroblasts is oxidant dependent and requires MAP kinases.
Journal: American journal of physiology. Lung cellular and molecular physiology 20030501
Title: Antiapoptotic action of carbon monoxide on cultured vascular smooth muscle cells.
Journal: Experimental biology and medicine (Maywood, N.J.) 20030501
Title: Inflammatory agonist stimulation and signal pathway of oxidative burst in neonatal chicken heterophils.
Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20030501
Title: Role of p38 mitogen-activated protein kinase in lung injury after burn trauma.
Journal: Shock (Augusta, Ga.) 20030501
Title: Regulation of ERK-mediated signal transduction by p38 MAP kinase in human monocytic THP-1 cells.
Journal: Journal of biochemistry 20030501
Title: Comparison between ischaemic and anisomycin-induced preconditioning: role of p38 MAPK.
Journal: Cardiovascular drugs and therapy 20030501
Title: Expression of angiogenic factor Cyr61 during neuronal cell death via the activation of c-Jun N-terminal kinase and serum response factor.
Journal: The Journal of biological chemistry 20030418
Title: The p38 and MK2 kinase cascade phosphorylates tuberin, the tuberous sclerosis 2 gene product, and enhances its interaction with 14-3-3.
Journal: The Journal of biological chemistry 20030418
Title: Concomitant recruitment of ERK1/2 and p38 MAPK signalling pathway is required for activation of cytoplasmic phospholipase A2 via ATP in articular chondrocytes.
Journal: The Journal of biological chemistry 20030418
Title: Involvement of p38 mitogen-activated protein kinase in heat shock protein 27 induction in human neutrophils.
Journal: European journal of pharmacology 20030418
Title: Signal pathway responsible for hepatocyte preconditioning by nitric oxide.
Journal: Free radical biology & medicine 20030415
Title: Tumor promoter arsenite stimulates histone H3 phosphoacetylation of proto-oncogenes c-fos and c-jun chromatin in human diploid fibroblasts.
Journal: The Journal of biological chemistry 20030411
Title: Kinase inhibitors: not just for kinases anymore.
Journal: Journal of medicinal chemistry 20030410
Title: P38 MAPK: critical molecule in thrombin-induced NF-kappa B-dependent leukocyte recruitment.
Journal: American journal of physiology. Heart and circulatory physiology 20030401
Title: Role of the different mitogen-activated protein kinase subfamilies in the stimulation of dog and human thyroid epithelial cell proliferation by cyclic adenosine 5'-monophosphate and growth factors.
Journal: Endocrinology 20030401
Title: Involvement of SAPK/JNK in basic fibroblast growth factor-induced vascular endothelial growth factor release in osteoblasts.
Journal: The Journal of endocrinology 20030401
Title: The isoprostane 8-iso-PGE2 stimulates endothelial cells to bind monocytes via cyclic AMP- and p38 MAP kinase-dependent signaling pathways.
Journal: Antioxidants & redox signaling 20030401
Title: Sphingosine 1-phosphate antagonizes human neutrophil apoptosis via p38 mitogen-activated protein kinase.
Journal: Cellular and molecular life sciences : CMLS 20030401
Title: Immediate-early gene induction by the stresses anisomycin and arsenite in human osteosarcoma cells involves MAPK cascade signaling to Elk-1, CREB and SRF.
Journal: Oncogene 20030327
Title: Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1).
Journal: The EMBO journal 20030317
Title: Effect of the lipid peroxidation product acrolein on tau phosphorylation in neural cells.
Journal: Journal of neuroscience research 20030315
Title: Induction of fetal hemoglobin expression by the histone deacetylase inhibitor apicidin.
Journal: Blood 20030301
Title: p38 Mitogen-activated protein kinase and extracellular signal-regulated kinases play distinct roles in the activation of dendritic cells by two representative haptens, NiCl2 and 2,4-dinitrochlorobenzene.
Journal: The Journal of investigative dermatology 20030301
Title: Potentiation of lipopolysaccharide-inducible cyclooxygenase 2 expression by C2-ceramide via c-Jun N-terminal kinase-mediated activation of CCAAT/enhancer binding protein beta in macrophages.
Journal: Molecular pharmacology 20030301
Title: Activation of p38 mitogen-activated protein kinase and activator protein-1 during the promotion of neurite extension of PC-12 cells by 15-deoxy-delta12,14-prostaglandin J2.
Journal: Molecular pharmacology 20030301
Title: Facilitation of fas mediated apoptosis of human chondrocytes by the proteasome inhibitor and actinomycin D.
Journal: The Journal of rheumatology 20030301
Title: High glucose activates the p38 MAPK pathway in cultured human peritoneal mesothelial cells.
Journal: Kidney international 20030301
Title: Cyclooxygenase-2-dependent and thromboxane-dependent vascular and bronchial responses are regulated via p38 mitogen-activated protein kinase in control and endotoxin-primed rat lungs.
Journal: Laboratory investigation; a journal of technical methods and pathology 20030301
Title: Evidence for a role of p38 kinase in hypoxia-inducible factor 1-independent induction of vascular endothelial growth factor expression by sodium arsenite.
Journal: The Journal of biological chemistry 20030227
Title: Type 2 deiodinase expression is stimulated by growth factors in human vascular smooth muscle cells.
Journal: Molecular and cellular endocrinology 20030227
Title: The phosphatidylinositol 3-kinase inhibitor LY294002 binds the estrogen receptor and inhibits 17beta-estradiol-induced transcriptional activity of an estrogen sensitive reporter gene.
Journal: Molecular and cellular endocrinology 20030227
Title: Cell proliferation induced by reactive oxygen species is mediated via mitogen-activated protein kinase in Chinese hamster lung fibroblast (V79) cells.
Journal: Molecules and cells 20030227
Title: Amphiregulin is a potent mitogen for the vascular smooth muscle cell line, A7r5.
Journal: Biochemical and biophysical research communications 20030221
Title: p38 MAP kinase--a molecular switch between VEGF-induced angiogenesis and vascular hyperpermeability.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030201
Title: Heat shock and Cd2+ exposure regulate PML and Daxx release from ND10 by independent mechanisms that modify the induction of heat-shock proteins 70 and 25 differently.
Journal: Journal of cell science 20030201
Title: Critical role of c-Jun N-terminal protein kinase activation in troglitazone-induced apoptosis of human HepG2 hepatoma cells.
Journal: Molecular pharmacology 20030201
Title: Vascular endothelial growth factor promotes proliferation of cortical neuron precursors by regulating E2F expression.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030201
Title: Tumour necrosis factor-alpha-induced expression of intercellular adhesion molecule-1 on human eosinophilic leukaemia EoL-1 cells is mediated by the activation of nuclear factor-kappaB pathway.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20030201
Title: Matrix metalloproteinase production by COOH-terminal heparin-binding fibronectin fragment in rheumatoid synovial cells.
Journal: Laboratory investigation; a journal of technical methods and pathology 20030201
Title: Cyclooxygenase-2 inhibitor NS-398 suppresses cell growth and constitutive production of granulocyte-colony stimulating factor and granulocyte macrophage-colony stimulating factor in lung cancer cells.
Journal: Cancer science 20030201
Title: Thrombin rapidly induces protein kinase D phosphorylation, and protein kinase C delta mediates the activation.
Journal: The Journal of biological chemistry 20030131
Title: Role of p38 MAPK in CYP2E1-dependent arachidonic acid toxicity.
Journal: The Journal of biological chemistry 20030110
Title: Gadolinium chloride reverses dimethylnitrosamine (DMN)-induced rat liver fibrosis with increased matrix metalloproteinases (MMPs) of Kupffer cells.
Journal: Life sciences 20030110
Title: Protein kinase C-alpha activation by phorbol ester induces secretion of gelatinase B/MMP-9 through ERK 1/2 pathway in capillary endothelial cells.
Journal: International journal of oncology 20030101
Title: Inhibition of p38 mitogen-activated protein kinase blocks activation of rat pancreatic stellate cells.
Journal: The Journal of pharmacology and experimental therapeutics 20030101
Title: Differential regulation of lipogenesis and leptin production by independent signaling pathways and rosiglitazone during human adipocyte differentiation.
Journal: Diabetes 20030101
Title: Cyclosporin A induces erythroid differentiation of K562 cells through p38 MAPK and ERK pathways.
Journal: American journal of hematology 20030101
Title: Induction of HL-60 cell differentiation by the p38 mitogen-activated protein kinase inhibitor SB203580 is mediated through the extracellular signal-regulated kinase signaling pathway.
Journal: Anti-cancer drugs 20030101
Title: Suppression of tumor necrosis factor-alpha by beta2-adrenoceptor activation: role of mitogen-activated protein kinases in renal mesangial cells.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030101
Title: A calcium/calmodulin kinase pathway connects brain-derived neurotrophic factor to the cyclic AMP-responsive transcription factor in the rat hippocampus.
Journal: Neuroscience 20030101
Title: Interfering with TGFbeta-induced Smad3 nuclear accumulation differentially affects TGFbeta-dependent gene expression.
Journal: Molecular cancer 20030101
Title: C-Jun N-terminal kinases/c-Jun and p38 pathways cooperate in ceramide-induced neuronal apoptosis.
Journal: Neuroscience 20030101
Title: Role of ERK, p38 and PI3-kinase in EGF receptor-mediated mitogenic signalling in cultured rat hepatocytes: requirement for sustained ERK activation.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20030101
Title: Ligand-independent tyrosine kinase signalling in RTH 149 trout hepatoma cells: comparison among heavy metals and pro-oxidants.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20030101
Title: Mechanisms underlying the inhibition of long-term potentiation by preconditioning stimulation in the hippocampus in vitro.
Journal: Neuroscience 20030101
Title: Pro-inflammatory cytokine-induced matrix metalloproteinase-1 (MMP-1) secretion in human pancreatic periacinar myofibroblasts.
Journal: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20030101
Title: p8 inhibits the growth of human pancreatic cancer cells and its expression is induced through pathways involved in growth inhibition and repressed by factors promoting cell growth.
Journal: Molecular cancer 20030101
Title: Role of the p38 MAP-kinase signaling pathway for Cx32 and claudin-1 in the rat liver.
Journal: Cell communication & adhesion 20030101
Title: Endothelial NADPH oxidase: mechanism of activation by low-density lipoprotein.
Journal: Endothelium : journal of endothelial cell research 20030101
Title: A dominant-negative p38 MAPK mutant and novel selective inhibitors of p38 MAPK reduce insulin-stimulated glucose uptake in 3T3-L1 adipocytes without affecting GLUT4 translocation.
Journal: The Journal of biological chemistry 20021227
Title: Salicylate suppresses macrophage nitric-oxide synthase-2 and cyclo-oxygenase-2 expression by inhibiting CCAAT/enhancer-binding protein-beta binding via a common signaling pathway.
Journal: The Journal of biological chemistry 20021220
Title: Antioxidants induce different phenotypes by a distinct modulation of signal transduction.
Journal: FEBS letters 20021218
Title: Activation of the Rb/E2F1 pathway by the nonproliferative p38 MAPK during Fas (APO1/CD95)-mediated neuronal apoptosis.
Journal: The Journal of biological chemistry 20021213
Title: Dilinoleoylphosphatidylcholine decreases acetaldehyde-induced TNF-alpha generation in Kupffer cells of ethanol-fed rats.
Journal: Biochemical and biophysical research communications 20021206
Title: TGF-beta effects on epithelial ion transport and barrier: reduced Cl- secretion blocked by a p38 MAPK inhibitor.
Journal: American journal of physiology. Cell physiology 20021201
Title: Gliclazide increases insulin receptor tyrosine phosphorylation but not p38 phosphorylation in insulin-resistant skeletal muscle cells.
Journal: The Journal of experimental biology 20021201
Title: Nuclear localisation of cytosolic phospholipase A2-alpha in the EA.hy.926 human endothelial cell line is proliferation dependent and modulated by phosphorylation.
Journal: Journal of cell science 20021201
Title: Agonists of proteinase-activated receptor 2 induce TNF-alpha secretion from astrocytoma cells.
Journal: Cell biochemistry and function 20021201
Title: Involvement of NMDA receptors and a p21Ras-like guanosine triphosphatase in the constitutive activation of nuclear factor-kappa-B in cortical neurons.
Journal: Experimental brain research 20021201
Title: The upregulation of CC chemokine receptor 7 and the increased migration of maturing dendritic cells to macrophage inflammatory protein 3beta and secondary lymphoid chemokine is mediated by the p38 stress-activated protein kinase pathway.
Journal: British journal of haematology 20021201
Title: CCL20/macrophage inflammatory protein-3alpha production in LPS-stimulated neutrophils is enhanced by the chemoattractant formyl-methionyl-leucyl-phenylalanine and IFN-gamma through independent mechanisms.
Journal: European journal of immunology 20021201
Title: Oxidative stress induces arachidonate release from human lung cells through the epithelial growth factor receptor pathway.
Journal: American journal of respiratory cell and molecular biology 20021201
Title: p38 mitogen-activated protein kinase regulates growth factor-induced mitogenesis of rat pulmonary myofibroblasts.
Journal: American journal of respiratory cell and molecular biology 20021201
Title: Requirement of caspase and p38MAPK activation in zinc-induced apoptosis in human leukemia HL-60 cells.
Journal: European journal of biochemistry 20021201
Title: Interleukin-1beta induces MUC2 gene expression and mucin secretion via activation of PKC-MEK/ERK, and PI3K in human airway epithelial cells.
Journal: Journal of Korean medical science 20021201
Title: Fas-mediated signaling enhances sensitivity of human soft tissue sarcoma cells to anticancer drugs by activation of p38 kinase.
Journal: Molecular cancer therapeutics 20021201
Title: Involvement of p38 MAP kinase during iron chelator-mediated apoptotic cell death.
Journal: Cellular immunology 20021201
Title: Identification of DC21 as a novel target gene counter-regulated by IL-12 and IL-4.
Journal: Journal of biochemistry and molecular biology 20021130
Title: Fyn and p38 signaling are both required for maximal hypertonic activation of the osmotic response element-binding protein/tonicity-responsive enhancer-binding protein (OREBP/TonEBP).
Journal: The Journal of biological chemistry 20021129
Title: Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to arsenic trioxide.
Journal: The Journal of biological chemistry 20021122
Title: Delta MEKK3:ER* activation induces a p38 alpha/beta 2-dependent cell cycle arrest at the G2 checkpoint.
Journal: Oncogene 20021121
Title: Antioxidants inhibit endothelin-1 (1-31)-induced proliferation of vascular smooth muscle cells via the inhibition of mitogen-activated protein (MAP) kinase and activator protein-1 (AP-1).
Journal: Biochemical pharmacology 20021115
Title: P38 mitogen-activated protein kinase inhibitor SB203580 has a bi-directional effect on iNOS expression and NO production.
Journal: European journal of pharmacology 20021115
Title: Nonrequirement of continuous stimulation with MCP-1 for cell migration and determination of directional migration by initial stimulation with chemokine.
Journal: Experimental cell research 20021115
Title: Alpha-synuclein regulates neuronal survival via Bcl-2 family expression and PI3/Akt kinase pathway.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021101
Title: Mitogen-activated protein kinases mediate stretch-induced c-fos mRNA expression in myometrial smooth muscle cells.
Journal: American journal of physiology. Cell physiology 20021101
Title: TGF-beta1 stimulates HO-1 via the p38 mitogen-activated protein kinase in A549 pulmonary epithelial cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20021101
Title: The neuroprotective agents chlomethiazole and SB203580 inhibit IL-1beta signalling but not its biosynthesis in rat cortical glial cells.
Journal: Journal of neurochemistry 20021101
Title: The role of MAPK pathways in the action of chemotherapeutic drugs.
Journal: Carcinogenesis 20021101
Title: Identification of JNK-dependent and -independent components of cerebellar granule neuron apoptosis.
Journal: Journal of neurochemistry 20021101
Title: 4-Hydroxy-2-nonenal enhances fibronectin production by IMR-90 human lung fibroblasts partly via activation of epidermal growth factor receptor-linked extracellular signal-regulated kinase p44/42 pathway.
Journal: Toxicology and applied pharmacology 20021101
Title: Acrolein activates mitogen-activated protein kinase signal transduction pathways in rat vascular smooth muscle cells.
Journal: Molecular and cellular biochemistry 20021101
Title: [Synergetic effect of mitogen-activated protein kinase pathway on expression of tumor necrosis factor alpha gene in RAW 264.7 cells induced by lipopolysaccharide].
Journal: Zhonghua yi xue za zhi 20021025
Title: Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB 203580-sensitive and -insensitive pathways.
Journal: The Biochemical journal 20021015
Title: Imidazole inhibitors of cytokine release: probing substituents in the 2 position.
Journal: Journal of medicinal chemistry 20021010
Title: Dietary salt intake activates MAP kinases in the rat kidney.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021001
Title: Metformin enhances insulin signalling in insulin-dependent and-independent pathways in insulin resistant muscle cells.
Journal: British journal of pharmacology 20021001
Title: Pharmacological analysis for mechanisms of GPI-80 release from tumour necrosis factor-alpha-stimulated human neutrophils.
Journal: British journal of pharmacology 20021001
Title: Activation of proteinase-activated receptor 1 stimulates epithelial chloride secretion through a unique MAP kinase- and cyclo-oxygenase-dependent pathway.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021001
Title: Vomitoxin-induced cyclooxygenase-2 gene expression in macrophages mediated by activation of ERK and p38 but not JNK mitogen-activated protein kinases.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20021001
Title: Phosphorylation of tyrosine hydroxylase in isolated mice adrenal glands.
Journal: Annals of the New York Academy of Sciences 20021001
Title: COM crystals activate the p38 mitogen-activated protein kinase signal transduction pathway in renal epithelial cells.
Journal: The Journal of biological chemistry 20020927
Title: Human gastrin-releasing peptide receptor mediates sustained CREB phosphorylation and transactivation in HuTu 80 duodenal cancer cells.
Journal: FEBS letters 20020911
Title: Inhibition of transforming growth factor-beta signaling by low molecular weight compounds interfering with ATP- or substrate-binding sites of the TGF beta type I receptor kinase.
Journal: Biochemistry 20020910
Title: Osmoregulation of endothelial nitric-oxide synthase gene expression in inner medullary collecting duct cells. Role in activation of the type A natriuretic peptide receptor.
Journal: The Journal of biological chemistry 20020906
Title: Thrombin stimulates dissociation and induction of HSP27 via p38 MAPK in vascular smooth muscle cells.
Journal: American journal of physiology. Heart and circulatory physiology 20020901
Title: Need for GLUT4 activation to reach maximum effect of insulin-mediated glucose uptake in brown adipocytes isolated from GLUT4myc-expressing mice.
Journal: Diabetes 20020901
Title: Apoptosis of human hepatic myofibroblasts promotes activation of matrix metalloproteinase-2.
Journal: Hepatology (Baltimore, Md.) 20020901
Title: Involvement of both extracellular signal-regulated kinase and c-jun N-terminal kinase pathways in the 12-O-tetradecanoylphorbol-13-acetate-induced upregulation of p21(Cip1) in colon cancer cells.
Journal: Molecular carcinogenesis 20020901
Title: Induction of fetal hemoglobin synthesis by valproate: modulation of MAP kinase pathways.
Journal: American journal of hematology 20020901
Title: Nitric oxide interferes with salivary mucin synthesis: involvement of ERK and p38 mitogen-activated protein kinase.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20020901
Title: Activated polymorphonuclear leukocytes induce cardiomyocyte apoptosis and the protective effects of carvedilol.
Journal: Methods and findings in experimental and clinical pharmacology 20020901
Title: The stress-activated protein kinases p38 alpha and JNK1 stabilize p21(Cip1) by phosphorylation.
Journal: The Journal of biological chemistry 20020816
Title: Transforming growth factor-beta1 modulates matrix metalloproteinase-9 production through the Ras/MAPK signaling pathway in transformed keratinocytes.
Journal: Biochemical and biophysical research communications 20020816
Title: Lipoteichoic acid-induced cyclooxygenase-2 expression requires activations of p44/42 and p38 mitogen-activated protein kinase signal pathways.
Journal: European journal of pharmacology 20020816
Title: The relative order of mK(ATP) channels, free radicals and p38 MAPK in preconditioning's protective pathway in rat heart.
Journal: Cardiovascular research 20020815
Title: Protein kinase B/Akt mediates cAMP- and cell swelling-stimulated Na+/taurocholate cotransport and Ntcp translocation.
Journal: The Journal of biological chemistry 20020809
Title: Fibroblast growth factor (FGF)-23 inhibits renal phosphate reabsorption by activation of the mitogen-activated protein kinase pathway.
Journal: The Journal of biological chemistry 20020802
Title: Phosphorylation and activation of mitogen- and stress-activated protein kinase-1 in adult rat cardiac myocytes by G-protein-coupled receptor agonists requires both extracellular-signal-regulated kinase and p38 mitogen-activated protein kinase.
Journal: The Biochemical journal 20020801
Title: A mitogen-activated protein kinase is involved in the inotropic but not chronotropic actions of adrenoceptor agonists and endothelin-1.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20020801
Title: Alpha(1)- and beta-adrenoceptor stimulation differentially activate p38-MAPK and atrial natriuretic peptide production in the perfused amphibian heart.
Journal: The Journal of experimental biology 20020801
Title: High glucose stimulates angiotensinogen gene expression via reactive oxygen species generation in rat kidney proximal tubular cells.
Journal: Endocrinology 20020801
Title: p38 MAPK-mediated signals are required for inducing osteoclast differentiation but not for osteoclast function.
Journal: Endocrinology 20020801
Title: Involvement of 85-kd cytosolic phospholipase A(2) and cyclooxygenase-2 in the proliferation of human cholangiocarcinoma cells.
Journal: Hepatology (Baltimore, Md.) 20020801
Title: Regulation of mediator secretion in human basophils by p38 mitogen-activated protein kinase: phosphorylation is sensitive to the effects of phosphatidylinositol 3-kinase inhibitors and calcium mobilization.
Journal: Journal of leukocyte biology 20020801
Title: Physiological levels of interleukin-18 stimulate multiple neutrophil functions through p38 MAP kinase activation.
Journal: Journal of leukocyte biology 20020801
Title: Norepinephrine enhances fibrosis mediated by TGF-beta in cardiac fibroblasts.
Journal: Hypertension (Dallas, Tex. : 1979) 20020801
Title: Arsenic trioxide induces apoptosis in chronic myelogenous leukemia K562 cells: possible involvement of p38 MAP kinase.
Journal: Journal of biochemistry and molecular biology 20020731
Title: The p38 and JNK pathways cooperate to trans-activate vitamin D receptor via c-Jun/AP-1 and sensitize human breast cancer cells to vitamin D(3)-induced growth inhibition.
Journal: The Journal of biological chemistry 20020719
Title: Transforming growth factor-beta induces expression of receptor activator of NF-kappa B ligand in vascular endothelial cells derived from bone.
Journal: The Journal of biological chemistry 20020719
Title: Activation of presynaptic P2X7-like receptors depresses mossy fiber-CA3 synaptic transmission through p38 mitogen-activated protein kinase.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020715
Title: Pyrazole urea-based inhibitors of p38 MAP kinase: from lead compound to clinical candidate.
Journal: Journal of medicinal chemistry 20020704
Title: Alcohol activates activator protein-1 and mitogen-activated protein kinases in rat pancreatic stellate cells.
Journal: The Journal of pharmacology and experimental therapeutics 20020701
Title: Pyridinylimidazole p38 mitogen-activated protein kinase inhibitors block intracellular Toxoplasma gondii replication.
Journal: International journal for parasitology 20020701
Title: Role of MAP kinase activation in interleukin-8 production by human BEAS-2B bronchial epithelial cells submitted to cyclic stretch.
Journal: American journal of respiratory cell and molecular biology 20020701
Title: Monocyte adhesion and transmigration induce tissue factor expression: role of the mitogen-activated protein kinases.
Journal: Shock (Augusta, Ga.) 20020701
Title: Molecular mechanisms of lipopolysaccharide-induced cyclooxygenase-2 expression in human neutrophils: involvement of the mitogen-activated protein kinase pathway and regulation by anti-inflammatory cytokines.
Journal: International immunology 20020701
Title: Hyperosmotic stimuli inhibit VCAM-1 expression in cultured endothelial cells via effects on interferon regulatory factor-1 expression and activity.
Journal: European journal of immunology 20020701
Title: Mechanisms involved in responses to the poroxisome proliferator WY-14,643 on gap junctional intercellular communication in V79 hamster fibroblasts.
Journal: Toxicology and applied pharmacology 20020701
Title: Modulation of phorbol ester-induced regulation of matrix metalloproteinases and tissue inhibitors of metalloproteinases by SB203580, a specific inhibitor of p38 mitogen-activated protein kinase.
Journal: Journal of neurosurgery 20020701
Title: Activation and translocation of p38 mitogen-activated protein kinase after stimulation of monocytes with contact sensitizers.
Journal: The Journal of investigative dermatology 20020701
Title: Regulation of c-myc stability by selective stress conditions and by MEKK1 requires aa 127-189 of c-myc.
Journal: Oncogene 20020627
Title: Lipopolysaccharide-mediated reactive oxygen species and signal transduction in the regulation of interleukin-1 gene expression.
Journal: The Journal of biological chemistry 20020621
Title: From imidazoles to pyrimidines: new inhibitors of cytokine release.
Journal: Journal of medicinal chemistry 20020620
Title: Activation of extracellular signal-regulated kinases is essential for pressure-induced proliferation of vascular smooth muscle cells.
Journal: European journal of pharmacology 20020620
Title: Synthesis and pharmacological characterization of a potent, orally active p38 kinase inhibitor.
Journal: Bioorganic & medicinal chemistry letters 20020617
Title: ATF-1 mediates protease-activated receptor-1 but not receptor tyrosine kinase-induced DNA synthesis in vascular smooth muscle cells.
Journal: The Journal of biological chemistry 20020614
Title: Distinct mechanisms of taxol-induced serine phosphorylation of the 66-kDa Shc isoform in A549 and RAW 264.7 cells.
Journal: Biochimica et biophysica acta 20020612
Title: IL-17 stimulates inflammatory responses via NF-kappaB and MAP kinase pathways in human colonic myofibroblasts.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20020601
Title: Regulation and function of COX-2 gene expression in isolated gastric parietal cells.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20020601
Title: Pharmacologically activated migration of aortic endothelial cells is mediated through p38 SAPK.
Journal: British journal of pharmacology 20020601
Title: Activation of p38 mitogen-activated protein kinase and nuclear factor-kappaB in tumour necrosis factor-induced eotaxin release of human eosinophils.
Journal: Clinical and experimental immunology 20020601
Title: Interferon-beta activates multiple signaling cascades in primary human microglia.
Journal: Journal of neurochemistry 20020601
Title: Cellular stresses profoundly inhibit protein synthesis and modulate the states of phosphorylation of multiple translation factors.
Journal: European journal of biochemistry 20020601
Title: Differentiation of human melanoma cells through p38 MAP kinase is associated with decreased retinoblastoma protein phosphorylation and cell cycle arrest.
Journal: Melanoma research 20020601
Title: Phosphorylation-dependent cellular localization and thermoprotective role of heat shock protein 25 in hippocampal progenitor cells.
Journal: The Journal of biological chemistry 20020531
Title: Critical role of cAMP-response element-binding protein for angiotensin II-induced hypertrophy of vascular smooth muscle cells.
Journal: The Journal of biological chemistry 20020524
Title: Relationship between p38 mitogen-activated protein kinase and small GTPase Rac for the activation of NADPH oxidase in bovine neutrophils.
Journal: Biochemical and biophysical research communications 20020524
Title: Signaling pathways involved in the physiological response of mussel hemocytes to bacterial challenge: the role of stress-activated p38 MAP kinases.
Journal: Developmental and comparative immunology 20020501
Title: Anti-inflammatory agents inhibit the induction of leptin by tumor necrosis factor-alpha.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20020501
Title: Functional role of p38 mitogen activated protein kinase in platelet activation induced by a thromboxane A2 analogue and by 8-iso-prostaglandin F2alpha.
Journal: Thrombosis and haemostasis 20020501
Title: Immunomodulatory effect of oxygen and pressure.
Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20020501
Title: Erk 1/2 differentially regulates the expression from the 1G/2G single nucleotide polymorphism in the MMP-1 promoter in melanoma cells.
Journal: Biochimica et biophysica acta 20020424
Title: Requirement of c-Jun N terminal kinase and P38 mitogen-activated protein kinase for anti-IgM-induced reduction in mitochondrial membrane potential in CH31 B lymphoma cells.
Journal: Immunology letters 20020422
Title: Distinct roles of mitogen-activated protein kinase pathways in GATA-4 transcription factor-mediated regulation of B-type natriuretic peptide gene.
Journal: The Journal of biological chemistry 20020419
Title: Oxalate selectively activates p38 mitogen-activated protein kinase and c-Jun N-terminal kinase signal transduction pathways in renal epithelial cells.
Journal: The Journal of biological chemistry 20020412
Title: Pathways of induction of peroxiredoxin I expression in osteoblasts: roles of p38 mitogen-activated protein kinase and protein kinase C.
Journal: The Journal of biological chemistry 20020405
Title: Rottlerin inhibits tonicity-dependent expression and action of TonEBP in a PKCdelta-independent fashion.
Journal: American journal of physiology. Renal physiology 20020401
Title: Dichotomal role of inhibition of p38 MAPK with SB 203580 in experimental colitis.
Journal: Gut 20020401
Title: Soluble fibrinogen modulates neutrophil functionality through the activation of an extracellular signal-regulated kinase-dependent pathway.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20020401
Title: p38 Mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: role in steroid-insensitive asthma.
Journal: The Journal of allergy and clinical immunology 20020401
Title: Inhibition of IL-8-mediated MAPK activation in human neutrophils by beta1 integrin ligands.
Journal: Inflammation 20020401
Title: Inhibition of interleukin-1-stimulated MAP kinases, activating protein-1 (AP-1) and nuclear factor kappa B (NF-kappa B) transcription factors down-regulates matrix metalloproteinase gene expression in articular chondrocytes.
Journal: Matrix biology : journal of the International Society for Matrix Biology 20020401
Title: Induction of iNOS expression in skeletal muscle by IL-1beta and NFkappaB activation: an in vitro and in vivo study.
Journal: Cardiovascular research 20020401
Title: Distribution, phosphorylation, and activities of Hsp25 in heat-stressed H9c2 myoblasts: a functional link to cytoprotection.
Journal: Cell stress & chaperones 20020401
Title: The p38 mitogen-activated protein kinase is involved in stress-induced phospholipase D activation in vascular smooth muscle cells.
Journal: Experimental & molecular medicine 20020331
Title: Phorbol esters inhibit fibroblast growth factor-2-stimulated fibroblast proliferation by a p38 MAP kinase dependent pathway.
Journal: Oncogene 20020327
Title: Activation of the p38 mitogen-activated protein kinase mediates the suppressive effects of type I interferons and transforming growth factor-beta on normal hematopoiesis.
Journal: The Journal of biological chemistry 20020308
Title: Involvement of p38 mitogen-activated protein kinase in PLL-AGE-induced cyclooxgenase-2 expression.
Journal: European journal of pharmacology 20020308
Title: Regulation of cyclooxygenase-2 expression by phospholipase D in human amnion-derived WISH cells.
Journal: Molecular pharmacology 20020301
Title: Differential role of MAP kinases in stimulation of hepatocyte growth by EGF and G-protein-coupled receptor agonists.
Journal: Biochemical and biophysical research communications 20020301
Title: Insulin and isoproterenol differentially regulate mitogen-activated protein kinase-dependent Na(+)-K(+)-2Cl(-) cotransporter activity in skeletal muscle.
Journal: Diabetes 20020301
Title: Identification of novel inhibitors of the transforming growth factor beta1 (TGF-beta1) type 1 receptor (ALK5).
Journal: Journal of medicinal chemistry 20020227
Title: IL-4 up-regulates the expression of tissue inhibitor of metalloproteinase-2 in dermal fibroblasts via the p38 mitogen-activated protein kinase dependent pathway.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20020215
Title: MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha.
Journal: Science (New York, N.Y.) 20020215
Title: The involvement of reactive oxygen species (ROS) and p38 mitogen-activated protein (MAP) kinase in TRAIL/Apo2L-induced apoptosis.
Journal: FEBS letters 20020213
Title: Upregulation by retinoic acid of transforming growth factor-beta-stimulated heat shock protein 27 induction in osteoblasts: involvement of mitogen-activated protein kinases.
Journal: Biochimica et biophysica acta 20020213
Title: Retinoic acid activation of the ERK pathway is required for embryonic stem cell commitment into the adipocyte lineage.
Journal: The Biochemical journal 20020201
Title: 1,25-dihydroxyvitamin D3 stimulates vascular endothelial growth factor release in aortic smooth muscle cells: role of p38 mitogen-activated protein kinase.
Journal: Archives of biochemistry and biophysics 20020201
Title: Regulation of sarcolemmal Na(+)/H(+) exchange by hydrogen peroxide in adult rat ventricular myocytes.
Journal: Cardiovascular research 20020201
Title: Role of mitogen-activated protein kinases and tyrosine kinases on IL-1-Induced NF-kappaB activation and iNOS expression in bovine articular chondrocytes.
Journal: Nitric oxide : biology and chemistry 20020201
Title: Mechanism of prostaglandin E2-stimulated heat shock protein 27 induction in osteoblast-like MC3T3-E1 cells.
Journal: The Journal of endocrinology 20020201
Title: p38 MAP kinase mediates the cell death induced by PrP106-126 in the SH-SY5Y neuroblastoma cells.
Journal: Neurobiology of disease 20020201
Title: Hyperosmotic and thermal stresses activate p38-MAPK in the perfused amphibian heart.
Journal: The Journal of experimental biology 20020201
Title: The effects of laminin-1 on spiral ganglion neurons are dependent on the MEK/ERK signaling pathway and are partially independent of Ras.
Journal: Hearing research 20020201
Title: ERK MAP Kinase is required in 1,25(OH)2D3-induced differentiation in human osteoblasts.
Journal: Immunopharmacology and immunotoxicology 20020201
Title: Regulation of p73 by c-Abl through the p38 MAP kinase pathway.
Journal: Oncogene 20020131
Title: Activation of the mitogen-activated protein kinase signaling pathway is instrumental in determining the ability of Mycobacterium avium to grow in murine macrophages.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20020115
Title: Role of mitogen-activated protein kinase pathway in acetylcholine-mediated in vitro relaxation of rat pulmonary artery.
Journal: European journal of pharmacology 20020102
Title: Inhibition of PI3K/p70 S6K and p38 MAPK cascades increases osteoblastic differentiation induced by BMP-2.
Journal: FEBS letters 20020102
Title: p38 Mitogen-activated protein kinase and phosphatidylinositol 3-kinase activities have opposite effects on human neutrophil apoptosis.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020101
Title: c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for mitoxantrone- and anisomycin-induced apoptosis in HL-60 cells.
Journal: Leukemia research 20020101
Title: Involvement of multiple kinase pathways in stimulation of gene transcription by hypertonicity.
Journal: American journal of physiology. Cell physiology 20020101
Title: alpha(1B)- and alpha(1D)-Adrenergic receptors exhibit different requirements for agonist and mitogen-activated protein kinase activation to regulate growth responses in rat 1 fibroblasts.
Journal: The Journal of pharmacology and experimental therapeutics 20020101
Title: Early growth response-1 gene (Egr-1) promoter induction by ionizing radiation in U87 malignant glioma cells in vitro.
Journal: European journal of biochemistry 20020101
Title: Abrogated leptin-induced cardiac contractile response in ventricular myocytes under spontaneous hypertension: role of Jak/STAT pathway.
Journal: Hypertension (Dallas, Tex. : 1979) 20020101
Title: Involvement of p38 mitogen-activated protein kinase in the cell growth inhibition by sodium arsenite.
Journal: Journal of cellular physiology 20020101
Title: Cyclooxygenase-2 in myocardium stimulation by angiotensin-II in cultured cardiac fibroblasts and role at acute myocardial infarction.
Journal: Journal of molecular and cellular cardiology 20020101
Title: Early signaling events induced by 280-nm UV irradiation.
Journal: European journal of biochemistry 20020101
Title: A role for MAP kinase in the antitumor activity of a nucleoside analog.
Journal: Cancer gene therapy 20020101
Title: Sympathoadrenal modulation of stress-activated signaling in burn trauma.
Journal: The Journal of burn care & rehabilitation 20020101
Title: Activation of p38 mitogen-activated protein kinase during normal mitosis in the developing retina.
Journal: Neuroscience 20020101
Title: High levels of MMP-1 expression in the absence of the 2G single nucleotide polymorphism is mediated by p38 and ERK1/2 mitogen-activated protein kinases in VMM5 melanoma cells.
Journal: Journal of cellular biochemistry 20020101
Title: p38 mitogen-activated protein kinase activation is required for thromboxane- induced contraction in perfused and pressurized rat mesenteric resistance arteries.
Journal: Journal of vascular research 20020101
Title: Glucose-dependent regulation of osteoclast H(+)-ATPase expression: potential role of p38 MAP-kinase.
Journal: Journal of cellular biochemistry 20020101
Title: [Transformation with the E1A + cHa-ras oncogenes enhances the trans-repressor function of the Elk-1 transcription factor].
Journal: Molekuliarnaia biologiia 20020101
Title: Stress-activated protein kinase/c-Jun N-terminal kinase (JNK) plays a part in endothelin-1-induced vascular endothelial growth factor synthesis in osteoblasts.
Journal: Journal of cellular biochemistry 20020101
Title: IL-1-mediated inhibition of IL-6-induced STAT3 activation is modulated by IL-4, MAP kinase inhibitors and redox state of HepG2 cells.
Journal: Folia histochemica et cytobiologica 20020101
Title: The induction of cyclooxygenase-2 mRNA in macrophages is biphasic and requires both CCAAT enhancer-binding protein beta (C/EBP beta ) and C/EBP delta transcription factors.
Journal: The Journal of biological chemistry 20011228
Title: Activation of lectin-like oxidized low-density lipoprotein receptor-1 induces apoptosis in cultured neonatal rat cardiac myocytes.
Journal: Circulation 20011211
Title: Multiple signaling pathways involved in activation of matrix metalloproteinase-9 (MMP-9) by heregulin-beta1 in human breast cancer cells.
Journal: Oncogene 20011206
Title: Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation.
Journal: Molecular and cellular biology 20011201
Title: Mechanisms of cytokine effects on G protein-coupled receptor-mediated signaling in airway smooth muscle.
Journal: American journal of physiology. Lung cellular and molecular physiology 20011201
Title: Role of p38 mitogen-activated protein kinase in chemokine-induced emigration and chemotaxis in vivo.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20011201
Title: Retinoid-related molecules induce cytochrome c release and apoptosis through activation of c-Jun NH(2)-terminal kinase/p38 mitogen-activated protein kinases.
Journal: Cancer research 20011201
Title: p38 MAPK activation triggers pharmacologically-induced beta-adrenergic preconditioning, but not ischaemic preconditioning.
Journal: Journal of molecular and cellular cardiology 20011201
Title: Angiotensin II promotes the phosphorylation of cyclic AMP-responsive element binding protein (CREB) at Ser133 through an ERK1/2-dependent mechanism.
Journal: Journal of neurochemistry 20011201
Title: Ras/MEK but not p38 signaling mediates NT-3-induced neurite extension from spiral ganglion neurons.
Journal: Journal of the Association for Research in Otolaryngology : JARO 20011201
Title: Hypoxia-induced regulation of MAPK phosphatase-1 as identified by subtractive suppression hybridization and cDNA microarray analysis.
Journal: The Journal of biological chemistry 20011130
Title: Involvement of MAP kinase cascades in Smad7 transcriptional regulation.
Journal: Biochemical and biophysical research communications 20011130
Title: Low M(r) protein tyrosine phosphatase inhibits growth and migration of vascular smooth muscle cells induced by platelet-derived growth factor.
Journal: Biochemical and biophysical research communications 20011130
Title: Minocycline blocks nitric oxide-induced neurotoxicity by inhibition p38 MAP kinase in rat cerebellar granule neurons.
Journal: Neuroscience letters 20011123
Title: Integrin-linked kinase controls neurite outgrowth in N1E-115 neuroblastoma cells.
Journal: The Journal of biological chemistry 20011116
Title: Potentiation of cadmium-induced cytotoxicity by sulfur amino acid deprivation through activation of extracellular signal-regulated kinase1/2 (ERK1/2) in conjunction with p38 kinase or c-jun N-terminal kinase (JNK). Complete inhibition of the potentiated toxicity by U0126 an ERK1/2 and p38 kinase inhibitor.
Journal: Biochemical pharmacology 20011115
Title: Stimulation of glucose transport by AMP-activated protein kinase via activation of p38 mitogen-activated protein kinase.
Journal: The Journal of biological chemistry 20011102
Title: Cytokine-induced p38 activation feedback regulates the prolonged activation of AKT cell survival pathway initiated by reactive oxygen species in response to UV irradiation in human keratinocytes.
Journal: International journal of oncology 20011101
Title: Activation of beta(2)-adrenoceptor prevents shiga toxin 2-induced TNF-alpha gene transcription.
Journal: Journal of the American Society of Nephrology : JASN 20011101
Title: Involvement of MAPK activation in bacterial endotoxin-inducible tissue factor upregulation in human monocytic THP-1 cells.
Journal: The Journal of surgical research 20011101
Title: TAK1/JNK and p38 have opposite effects on rat hepatic stellate cells.
Journal: Hepatology (Baltimore, Md.) 20011101
Title: PKC- and ERK-dependent activation of I kappa B kinase by lipopolysaccharide in macrophages: enhancement by P2Y receptor-mediated CaMK activation.
Journal: British journal of pharmacology 20011101
Title: p38 MAP kinase mediates stress-induced leukotriene synthesis in a human B-lymphocyte cell line.
Journal: Journal of leukocyte biology 20011101
Title: Macrophage stimulating protein (MSP) evokes superoxide anion production by human macrophages of different origin.
Journal: British journal of pharmacology 20011101
Title: p38 MAPK and Ca2+ contribute to hydrogen peroxide-induced increase of permeability in vascular endothelial cells but ERK does not.
Journal: Free radical research 20011101
Title: Microtubule-targeting drugs induce bcl-2 phosphorylation and association with Pin1.
Journal: Neoplasia (New York, N.Y.) 20011101
Title: Arsenite activation of P13K/AKT cell survival pathway is mediated by p38 in cultured human keratinocytes.
Journal: Molecular medicine (Cambridge, Mass.) 20011101
Title: Protein kinase CK2 is involved in G2 arrest and apoptosis following spindle damage in epithelial cells.
Journal: Oncogene 20011025
Title: Nerve growth factor inhibits apoptosis in memory B lymphocytes via inactivation of p38 MAPK, prevention of Bcl-2 phosphorylation, and cytochrome c release.
Journal: The Journal of biological chemistry 20011019
Title: Osmotic shock induces G1 arrest through p53 phosphorylation at Ser33 by activated p38MAPK without phosphorylation at Ser15 and Ser20.
Journal: The Journal of biological chemistry 20011019
Title: Indomethacin-induced radiosensitization and inhibition of ionizing radiation-induced NF-kappaB activation in HeLa cells occur via a mechanism involving p38 MAP kinase.
Journal: Cancer research 20011015
Title: Induction of the IL-13 receptor alpha2-chain by IL-4 and IL-13 in human keratinocytes: involvement of STAT6, ERK and p38 MAPK pathways.
Journal: Oncogene 20011011
Title: Tumor cell differentiation by butyrate and environmental stress.
Journal: Cancer letters 20011010
Title: Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharide-induced signaling pathways involved in the release of tumor necrosis factor-alpha.
Journal: Biochemical pharmacology 20011001
Title: Agonist-specific cross talk between ERKs and p38(mapk) regulates PGI(2) synthesis in endothelium.
Journal: American journal of physiology. Cell physiology 20011001
Title: Acetaminophen induces apoptosis of C6 glioma cells by activating the c-Jun NH(2)-terminal protein kinase-related cell death pathway.
Journal: Molecular pharmacology 20011001
Title: Phosphorylation-dependent nucleocytoplasmic shuttling of pancreatic duodenal homeobox-1.
Journal: Diabetes 20011001
Title: Hypertonic saline activation of p38 MAPK primes the PMN respiratory burst.
Journal: Shock (Augusta, Ga.) 20011001
Title: NF-kappaB and the MAP kinases/AP-1 pathways are both involved in interleukin-6 and interleukin-8 expression in fibroblast-like synoviocytes stimulated by protein I/II, a modulin from oral streptococci.
Journal: Cellular microbiology 20011001
Title: Involvement of p38-mitogen-activated protein kinase in Staphylococcus aureus-induced neutrophil apoptosis.
Journal: Journal of leukocyte biology 20011001
Title: Pharmacological comparison of LTB(4)-induced NADPH oxidase activation in adherent and non-adherent guinea-pig eosinophils.
Journal: British journal of pharmacology 20011001
Title: Expression of cyclooxygenase-2 in human neutrophils activated by Helicobacter pylori water-soluble proteins: possible involvement of NF-kappaB and MAP kinase signaling pathway.
Journal: Digestive diseases and sciences 20011001
Title: Interleukin-1beta induces cyclo-oxygenase-2 expression in gastric cancer cells by the p38 and p44/42 mitogen-activated protein kinase signaling pathways.
Journal: Journal of gastroenterology and hepatology 20011001
Title: Crosstalk between p38, Hsp25 and Akt in spinal motor neurons after sciatic nerve injury.
Journal: Brain research. Molecular brain research 20010930
Title: Mycobacteria-induced TNF-alpha and IL-10 formation by human macrophages is differentially regulated at the level of mitogen-activated protein kinase activity.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010915
Title: The absence of activator protein 1-dependent gene expression in THP-1 macrophages stimulated with phorbol esters is due to lack of p38 mitogen-activated protein kinase activation.
Journal: The Journal of biological chemistry 20010907
Title: Role of G proteins and modulation of p38 MAPK activation in the protection by nitric oxide against ischemia-reoxygenation injury.
Journal: Biochemical and biophysical research communications 20010907
Title: R(+)-methanandamide induces cyclooxygenase-2 expression in human neuroglioma cells via a non-cannabinoid receptor-mediated mechanism.
Journal: Biochemical and biophysical research communications 20010907
Title: Pyridinyl imidazole inhibitor SB203580 activates p44/42 mitogen-activated protein kinase and induces the differentiation of human myeloid leukemia cells.
Journal: Leukemia research 20010901
Title: Inhibition of neutrophil apoptosis by acrolein: a mechanism of tobacco-related lung disease?
Journal: American journal of physiology. Lung cellular and molecular physiology 20010901
Title: Regulation of interleukin-8 gene expression after phagocytosis of zymosan by human monocytic cells.
Journal: Journal of leukocyte biology 20010901
Title: Involvement of p38 kinase in hydroxyurea-induced differentiation of K562 cells.
Journal: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 20010901
Title: Focal adhesion features during myofibroblastic differentiation are controlled by intracellular and extracellular factors.
Journal: Journal of cell science 20010901
Title: Insulin up-regulates tumor necrosis factor-alpha production in macrophages through an extracellular-regulated kinase-dependent pathway.
Journal: The Journal of biological chemistry 20010831
Title: Regulation of MAP kinase by the BMP-4/TAK1 pathway in Xenopus ectoderm.
Journal: Developmental biology 20010815
Title: Sensitized mast cells migrate toward the antigen: a response regulated by p38 mitogen-activated protein kinase and Rho-associated coiled-coil-forming protein kinase.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010815
Title: An IkappaBalpha inhibitor causes leukemia cell death through a p38 MAP kinase-dependent, NF-kappaB-independent mechanism.
Journal: Cancer research 20010815
Title: Inhibitors of mitogen-activated protein kinases differentially regulate eosinophil-activating cytokine release from human airway smooth muscle.
Journal: American journal of respiratory and critical care medicine 20010815
Title: Cardioprotective effect afforded by transient exposure to phosphodiesterase III inhibitors: the role of protein kinase A and p38 mitogen-activated protein kinase.
Journal: Circulation 20010807
Title: A role for the extracellular signal-regulated kinase and p38 mitogen-activated protein kinases in interleukin-1 beta-stimulated delayed signal tranducer and activator of transcription 3 activation, atrial natriuretic factor expression, and cardiac myocyte morphology.
Journal: The Journal of biological chemistry 20010803
Title: Ligands of macrophage scavenger receptor induce cytokine expression via differential modulation of protein kinase signaling pathways.
Journal: The Journal of biological chemistry 20010803
Title: Control of survival of proliferating L1210 cells by soluble guanylate cyclase and p44/42 mitogen-activated protein kinase modulators.
Journal: Biochemical pharmacology 20010801
Title: Decreased p38 MAPK activity in end-stage failing human myocardium: p38 MAPK alpha is the predominant isoform expressed in human heart.
Journal: Journal of molecular and cellular cardiology 20010801
Title: Mitogen-activated protein kinases mediate heat shock-induced delayed protection in mouse heart.
Journal: American journal of physiology. Heart and circulatory physiology 20010801
Title: Mechanism of prostaglandin D(2)-stimulated heat shock protein 27 induction in osteoblasts.
Journal: Cellular signalling 20010801
Title: Tyrosine hydroxylase phosphorylation in bovine adrenal chromaffin cells: the role of MAPKs after angiotensin II stimulation.
Journal: Journal of neurochemistry 20010801
Title: Regulation of MARCKS and MARCKS-related protein expression in BV-2 microglial cells in response to lipopolysaccharide.
Journal: Journal of neurochemistry 20010801
Title: Induction of cyclo-oxygenase-2 in human endothelial cells by SIN-1 in the absence of prostaglandin production.
Journal: British journal of pharmacology 20010801
Title: Activation of the p38 and p42/p44 mitogen-activated protein kinase families by the histamine H(1) receptor in DDT(1)MF-2 cells.
Journal: British journal of pharmacology 20010801
Title: Tumour necrosis factor-alpha potentiates CR3-induced respiratory burst by activating p38 MAP kinase in human neutrophils.
Journal: Immunology 20010801
Title: Distinct involvement of NF-kappaB and p38 mitogen-activated protein kinase pathways in serum deprivation-mediated stimulation of inducible nitric oxide synthase and its inhibition by 4-hydroxynonenal.
Journal: Journal of cellular biochemistry 20010801
Title: Platelet-derived growth factor BB-induced p38 mitogen-activated protein kinase activation causes cell growth, but not apoptosis, in vascular smooth muscle cells.
Journal: Endocrine journal 20010801
Title: Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharide-induced release of nitric oxide.
Journal: Chemico-biological interactions 20010731
Title: Induction of apoptosis and Fas receptor/Fas ligand expression by ischemia/reperfusion in cardiac myocytes requires serine 727 of the STAT-1 transcription factor but not tyrosine 701.
Journal: The Journal of biological chemistry 20010727
Title: The p38 MAPK pathway mediates the growth inhibitory effects of interferon-alpha in BCR-ABL-expressing cells.
Journal: The Journal of biological chemistry 20010727
Title: Rac1 protects epithelial cells against anoikis.
Journal: The Journal of biological chemistry 20010727
Title: Involvement of ERK and p38 MAP kinase in oxidative stress-induced phospholipase D activation in PC12 cells.
Journal: Neuroreport 20010720
Title: Involvement of p38 MAP kinase pathway in the synergistic activation of PACAP mRNA expression by NGF and PACAP in PC12h cells.
Journal: Biochemical and biophysical research communications 20010720
Title: Rac is activated by tumor necrosis factor alpha and is involved in activation of Erk.
Journal: Biochemical and biophysical research communications 20010720
Title: Implication of the small GTPase Rac1 in the apoptosis induced by UV in Rat-2 fibroblasts.
Journal: Biochemical and biophysical research communications 20010720
Title: MEK6 regulates human involucrin gene expression via a p38alpha - and p38delta -dependent mechanism.
Journal: The Journal of biological chemistry 20010720
Title: PKCdelta-dependent deubiquitination and stabilization of Gadd45 in A431 cells overexposed to EGF.
Journal: Biochemical and biophysical research communications 20010713
Title: Production of proinflammatory cytokines by resident tissue macrophages after phagocytosis of apoptotic cells.
Journal: Cellular immunology 20010710
Title: Cytosolic phospholipase A2 activation by the p38 kinase inhibitor SB203580 in rabbit aortic smooth muscle cells.
Journal: The Journal of pharmacology and experimental therapeutics 20010701
Title: Autoregulation of cell-specific MAP kinase control of the tryptophan hydroxylase promoter.
Journal: The Journal of biological chemistry 20010615
Title: Rac1 activity is required for the activation of hypoxia-inducible factor 1.
Journal: The Journal of biological chemistry 20010615
Title: Mechanism for Helicobacter pylori stimulation of interleukin-8 production in a gastric epithelial cell line (MKN 28): roles of mitogen-activated protein kinase and interleukin-1beta.
Journal: Biochemical pharmacology 20010615
Title: Regulation of the levels of small heat-shock proteins during differentiation of C2C12 cells.
Journal: Experimental cell research 20010610
Title: MKK6/3 and p38 MAPK pathway activation is not necessary for insulin-induced glucose uptake but regulates glucose transporter expression.
Journal: The Journal of biological chemistry 20010608
Title: Stimulation of astrocyte-enriched culture with C2 ceramide increases proenkephalin mRNA: involvement of cAMP-response element binding protein and mitogen activated protein kinases.
Journal: Brain research 20010608
Title: Transient activation of Jun N-terminal kinases and protection from apoptosis by the insulin-like growth factor I receptor can be suppressed by dicumarol.
Journal: The Journal of biological chemistry 20010601
Title: The p38 mitogen-activated protein kinase mediates cytoskeletal remodeling in pulmonary microvascular endothelial cells upon intracellular adhesion molecule-1 ligation.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010601
Title: The antihyperglycemic drug alpha-lipoic acid stimulates glucose uptake via both GLUT4 translocation and GLUT4 activation: potential role of p38 mitogen-activated protein kinase in GLUT4 activation.
Journal: Diabetes 20010601
Title: Involvement of p38 in apoptosis-associated membrane blebbing and nuclear condensation.
Journal: Molecular biology of the cell 20010601
Title: Ceramide-induced apoptosis in cortical neurons is mediated by an increase in p38 phosphorylation and not by the decrease in ERK phosphorylation.
Journal: The European journal of neuroscience 20010601
Title: Delay in oral mucosal ulcer healing by aspirin is linked to the disturbances in p38 mitogen-activated protein kinase activation.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20010601
Title: [Activation of p38 and c-Jun NH2-terminal kinase mitogen-activated protein kinases in human prostate carcinoma cell lines with different metastatic potentials].
Journal: Zhonghua bing li xue za zhi = Chinese journal of pathology 20010601
Title: Arachidonic acid modulates the spatiotemporal characteristics of agonist-evoked Ca2+ waves in mouse pancreatic acinar cells.
Journal: The Journal of biological chemistry 20010518
Title: Distinct signaling pathways for MCP-1-dependent integrin activation and chemotaxis.
Journal: The Journal of biological chemistry 20010511
Title: Phenoxypyrimidine inhibitors of p38alpha kinase: synthesis and statistical evaluation of the p38 inhibitory potencies of a series of 1-(piperidin-4-yl)-4-(4-fluorophenyl)-5-(2-phenoxypyrimidin-4-yl) imidazoles.
Journal: Bioorganic & medicinal chemistry letters 20010507
Title: Atrial natriuretic peptide inhibits tumor necrosis factor-alpha production by interferon-gamma-activated macrophages via suppression of p38 mitogen-activated protein kinase and nuclear factor-kappa B activation.
Journal: Regulatory peptides 20010505
Title: p38 MAP kinase negatively regulates cyclin D1 expression in airway smooth muscle cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20010501
Title: Endotoxin (LPS) stimulates 4E-BP1/PHAS-I phosphorylation in macrophages.
Journal: The Journal of surgical research 20010501
Title: ERK induces p35, a neuron-specific activator of Cdk5, through induction of Egr1.
Journal: Nature cell biology 20010501
Title: Critical role of Rho-kinase and MEK/ERK pathways for angiotensin II-induced plasminogen activator inhibitor type-1 gene expression.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20010501
Title: Role of extracellular signal-regulated kinase and phosphatidylinositol-3 kinase in chemoattractant and LPS delay of constitutive neutrophil apoptosis.
Journal: Cellular signalling 20010501
Title: Transcriptional cross-talk between Smad, ERK1/2, and p38 mitogen-activated protein kinase pathways regulates transforming growth factor-beta-induced aggrecan gene expression in chondrogenic ATDC5 cells.
Journal: The Journal of biological chemistry 20010427
Title: Phosphorylation of xanthine dehydrogenase/oxidase in hypoxia.
Journal: The Journal of biological chemistry 20010427
Title: The p38 mitogen-activated kinase pathway regulates the human interleukin-10 promoter via the activation of Sp1 transcription factor in lipopolysaccharide-stimulated human macrophages.
Journal: The Journal of biological chemistry 20010427
Title: Manganese superoxide dismutase signals matrix metalloproteinase expression via H2O2-dependent ERK1/2 activation.
Journal: The Journal of biological chemistry 20010427
Title: Mechanisms underlying neuronal death induced by chromogranin A-activated microglia.
Journal: The Journal of biological chemistry 20010420
Title: Osteopontin gene regulation by oscillatory fluid flow via intracellular calcium mobilization and activation of mitogen-activated protein kinase in MC3T3-E1 osteoblasts.
Journal: The Journal of biological chemistry 20010420
Title: Expression of 74-kDa histidine decarboxylase protein in a macrophage-like cell line RAW 264.7 and inhibition by dexamethasone.
Journal: European journal of pharmacology 20010420
Title: Forskolin inhibits expression of inducible nitric oxide synthase mRNA via inhibiting the mitogen activated protein kinase in C6 cells.
Journal: Brain research. Molecular brain research 20010418
Title: Activation of p44/p42 MAP kinase in striatal neurons via kainate receptors and PI3 kinase.
Journal: Brain research. Molecular brain research 20010418
Title: p38 mitogen-activated kinase is a bidirectional regulator of human fibroblast collagenase-1 induction by three-dimensional collagen lattices.
Journal: The Biochemical journal 20010415
Title: Activation and priming of neutrophil nicotinamide adenine dinucleotide phosphate oxidase and phospholipase A(2) are dissociated by inhibitors of the kinases p42(ERK2) and p38(SAPK) and by methyl arachidonyl fluorophosphonate, the dual inhibitor of cytosolic and calcium-independent phospholipase A(2).
Journal: Blood 20010415
Title: Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010415
Title: Stress kinase inhibition modulates acute experimental pancreatitis.
Journal: World journal of gastroenterology 20010415
Title: Synergistic induction of apoptosis in human leukemia cells (U937) exposed to bryostatin 1 and the proteasome inhibitor lactacystin involves dysregulation of the PKC/MAPK cascade.
Journal: Blood 20010401
Title: p38 MAPK activity is not increased early during sustained coronary artery occlusion in preconditioned versus control rabbit heart.
Journal: Journal of molecular and cellular cardiology 20010401
Title: Benzene-extracted components are important for the major activity of diesel exhaust particles: effect on interleukin-8 gene expression in human bronchial epithelial cells.
Journal: American journal of respiratory cell and molecular biology 20010401
Title: Role of p38 MAP kinase in LPS-induced airway inflammation in the rat.
Journal: British journal of pharmacology 20010401
Title: Inhibition of p38MAP kinase potentiates the JNK/SAPK pathway and AP-1 activity in monocytic but not in macrophage or granulocytic differentiation of HL60 cells.
Journal: Journal of cellular biochemistry 20010401
Title: Activation of mitogen-activated protein kinases p42/44, p38, and stress-activated protein kinases in myelo-monocytic cells by Treponema lipoteichoic acid.
Journal: The Journal of biological chemistry 20010330
Title: Reperfusion-activated Akt kinase prevents apoptosis in transgenic mouse hearts overexpressing insulin-like growth factor-1.
Journal: Circulation research 20010330
Title: Thrombin activates p38 mitogen-activated protein kinase in vascular smooth muscle cells.
Journal: Life sciences 20010316
Title: A critical role for p38 mitogen-activated protein kinase in the maturation of human blood-derived dendritic cells induced by lipopolysaccharide, TNF-alpha, and contact sensitizers.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010315
Title: Involvement of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase in alpha1B-adrenergic receptor/Galphaq-induced inhibition of cell proliferation.
Journal: Biochemical and biophysical research communications 20010309
Title: Identification of a novel inhibitor of LPS-induced TNF-alpha production with antiproliferative activity in monocyte/macrophages.
Journal: Biochemical and biophysical research communications 20010309
Title: Stress-induced inhibition of ERK1 and ERK2 by direct interaction with p38 MAP kinase.
Journal: The Journal of biological chemistry 20010309
Title: Combinations of ERK and p38 MAPK inhibitors ablate tumor necrosis factor-alpha (TNF-alpha ) mRNA induction. Evidence for selective destabilization of TNF-alpha transcripts.
Journal: The Journal of biological chemistry 20010302
Title: Tumor necrosis factor-alpha-induced cyclooxygenase-2 expression via sequential activation of ceramide-dependent mitogen-activated protein kinases, and IkappaB kinase 1/2 in human alveolar epithelial cells.
Journal: Molecular pharmacology 20010301
Title: Signaling mechanism underlying COX-2 induction by lysophosphatidylcholine.
Journal: Biochemical and biophysical research communications 20010301
Title: Differential involvement of p38 mitogen-activated protein kinase and phosphatidyl inositol 3-kinase in the IL-1-mediated NF-kappa B and AP-1 activation.
Journal: International immunopharmacology 20010301
Title: Mitogen-activated protein kinase p38 mediates regulation of chondrocyte differentiation by parathyroid hormone.
Journal: The Journal of biological chemistry 20010216
Title: Cytoprotection by Jun kinase during nitric oxide-induced cardiac myocyte apoptosis.
Journal: Circulation research 20010216
Title: Regulation of p42/p44 MAPK and p38 MAPK by the adenosine A(1) receptor in DDT(1)MF-2 cells.
Journal: European journal of pharmacology 20010216
Title: Bacterial lipopolysaccharide activates HIV long terminal repeat through Toll-like receptor 4.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010215
Title: The Epstein-Barr virus latent membrane protein 1 induces interleukin-10 in Burkitt's lymphoma cells but not in Hodgkin's cells involving the p38/SAPK2 pathway.
Journal: Virology 20010215
Title: Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to all-trans-retinoic acid.
Journal: The Journal of biological chemistry 20010209
Title: Inhibitors of p38 MAP kinase increase the survival of transplanted dopamine neurons.
Journal: Brain research 20010209
Title: Opposite effects of the Hsp90 inhibitor Geldanamycin: induction of apoptosis in PC12, and differentiation in N2A cells.
Journal: FEBS letters 20010209
Title: p38 Kinase-dependent MAPKAPK-2 activation functions as 3-phosphoinositide-dependent kinase-2 for Akt in human neutrophils.
Journal: The Journal of biological chemistry 20010202
Title: Involvement of p38 MAP Kinase in the inhibitory effects of phosphatidylserine liposomes on nitric oxide production from macrophages stimulated with LPS.
Journal: Biochemical and biophysical research communications 20010202
Title: Vanadium stimulates human bronchial epithelial cells to produce heparin-binding epidermal growth factor-like growth factor: a mitogen for lung fibroblasts.
Journal: American journal of respiratory cell and molecular biology 20010201
Title: SB 239063, a second-generation p38 mitogen-activated protein kinase inhibitor, reduces brain injury and neurological deficits in cerebral focal ischemia.
Journal: The Journal of pharmacology and experimental therapeutics 20010201
Title: The stress-induced MAP kinase p38 regulates endocytic trafficking via the GDI:Rab5 complex.
Journal: Molecular cell 20010201
Title: Apoptosis of PC12 cells by 4-hydroxy-2-nonenal is mediated through selective activation of the c-Jun N-terminal protein kinase pathway.
Journal: Chemico-biological interactions 20010130
Title: Cleavage of mitogen-activated protein kinases in human neutrophils undergoing apoptosis: role in decreased responsiveness to inflammatory cytokines.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010115
Title: Apoptosis signal-regulating kinase 1 (ASK1) is an intracellular inducer of keratinocyte differentiation.
Journal: The Journal of biological chemistry 20010112
Title: Taxol-induced apoptosis depends on MAP kinase pathways (ERK and p38) and is independent of p53.
Journal: Oncogene 20010111
Title: p38 kinase inhibitors for the treatment of arthritis and osteoporosis: thienyl, furyl, and pyrrolyl ureas.
Journal: Bioorganic & medicinal chemistry letters 20010108
Title: Transient interaction of activated platelets with endothelial cells induces expression of monocyte-chemoattractant protein-1 via a p38 mitogen-activated protein kinase mediated pathway. Implications for atherogenesis.
Journal: Cardiovascular research 20010101
Title: Phosphatidylinositol-3,4,5-trisphosphate is required for insulin-like growth factor 1-mediated survival of 3T3-L1 preadipocytes.
Journal: Endocrinology 20010101
Title: The p38 mitogen-activated protein kinase pathway regulates interleukin-6 synthesis in response to tumor necrosis factor in osteoblasts.
Journal: Bone 20010101
Title: Intracellular glutathione regulates tumour necrosis factor-alpha-induced p38 MAP kinase activation and RANTES production by human bronchial epithelial cells.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20010101
Title: Evolution of an immune suppressive macrophage phenotype as a product of P38 MAPK activation in polymicrobial sepsis.
Journal: Shock (Augusta, Ga.) 20010101
Title: Expression of vascular endothelial growth factor in human monocyte/macrophages stimulated with lipopolysaccharide.
Journal: Thrombosis and haemostasis 20010101
Title: Homocysteine stimulates the expression of monocyte chemoattractant protein-1 in endothelial cells leading to enhanced monocyte chemotaxis.
Journal: Molecular and cellular biochemistry 20010101
Title: MEK and p38MAPK inhibitors potentiate TNF-alpha induced apoptosis in U937 cells.
Journal: Anticancer research 20010101
Title: Increased sensitivity to sodium salicylate-induced apoptosis in drug-resistant leukemia L1210 cells.
Journal: Anticancer research 20010101
Title: Analysis of pharmacologic inhibitors of Jun N-terminal kinases.
Journal: Methods in enzymology 20010101
Title: Selective regulation of T cell IL-5 synthesis by OM-01, JTE-711 and p38 MAP kinase inhibitor: independent control of Th2 cytokines, IL-4 and IL-5.
Journal: International archives of allergy and immunology 20010101
Title: Protein kinase inhibitors can suppress stress-induced dissociation of Hsp27.
Journal: Cell stress & chaperones 20010101
Title: JNK phosphorylates the HSF1 transcriptional activation domain: role of JNK in the regulation of the heat shock response.
Journal: Journal of cellular biochemistry 20010101
Title: Inhibition of p38 kinase mimics survival signal-linked protection against apoptosis in rat cerebellar granule neurons.
Journal: Cellular & molecular biology letters 20010101
Title: Regulation of taurine transport in murine macrophages.
Journal: Amino acids 20010101
Title: Fluid shear stress suppresses interleukin 8 production by vascular endothelial cells.
Journal: Biorheology 20010101
Title: Roles of extracellular signal-regulated kinase and p38 mitogen-activated protein kinase in apoptosis of human monoblastic leukemia U937 cells by lectin-II isolated from Korean mistletoe.
Journal: In vitro & molecular toxicology 20010101
Title: Role of p38(MAPK) in cell volume regulation of perfused rat liver.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20010101
Title: Salicylate-induced growth arrest is associated with inhibition of p70s6k and down-regulation of c-myc, cyclin D1, cyclin A, and proliferating cell nuclear antigen.
Journal: The Journal of biological chemistry 20001208
Title: Spontaneous shift in transcriptional profile of explanted glomeruli via activation of the MAP kinase family.
Journal: American journal of physiology. Renal physiology 20001101
Title: Arsenite induces apoptosis of murine T lymphocytes through membrane raft-linked signaling for activation of c-Jun amino-terminal kinase.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20001015
Title: Specificity and mechanism of action of some commonly used protein kinase inhibitors.
Journal: The Biochemical journal 20001001
Title: Role of caspases in dexamethasone-induced apoptosis and activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase in human eosinophils.
Journal: Clinical and experimental immunology 20001001
Title: Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor.
Journal: The Journal of biological chemistry 20000908
Title: Expression of the chemokine receptors CXCR1 and CXCR2 on granulocytes in human endotoxemia and tuberculosis: involvement of the p38 mitogen-activated protein kinase pathway.
Journal: The Journal of infectious diseases 20000901
Title: Anti-apoptotic effect of quercetin: intervention in the JNK- and ERK-mediated apoptotic pathways.
Journal: Kidney international 20000901
Title: p38 mitogen-activated protein kinase mediates bid cleavage, mitochondrial dysfunction, and caspase-3 activation during apoptosis induced by singlet oxygen but not by hydrogen peroxide.
Journal: The Journal of biological chemistry 20000825
Title: NF-kappa B regulates the LPS-induced expression of interleukin 12 p40 in murine peritoneal macrophages: roles of PKC, PKA, ERK, p38 MAPK, and proteasome.
Journal: Cellular immunology 20000825
Title: Residual type 1 immunity in patients genetically deficient for interleukin 12 receptor beta1 (IL-12Rbeta1): evidence for an IL-12Rbeta1-independent pathway of IL-12 responsiveness in human T cells.
Journal: The Journal of experimental medicine 20000821
Title: Phosphorylation of elk-1 by MEK/ERK pathway is necessary for c-fos gene activation during cardiac myocyte hypertrophy.
Journal: Journal of molecular and cellular cardiology 20000801
Title: Synergistic effect of diesel organic extracts and allergen Der p 1 on the release of chemokines by peripheral blood mononuclear cells from allergic subjects: involvement of the map kinase pathway.
Journal: American journal of respiratory cell and molecular biology 20000801
Title: Mechanisms of induction of human tissue inhibitor of metalloproteinases-1 (TIMP-1) gene expression by all-trans retinoic acid in combination with basic fibroblast growth factor.
Journal: European journal of biochemistry 20000701
Title: Vanadium-induced kappaB-dependent transcription depends upon peroxide-induced activation of the p38 mitogen-activated protein kinase.
Journal: American journal of respiratory cell and molecular biology 20000701
Title: Activation of extracellular signal-regulated kinase (ERK)1/2 contributes to cytokine-induced apoptosis in purified rat pancreatic beta-cells.
Journal: European cytokine network 20000601
Title: 5-lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20000509
Title: Diesel exhaust particles up-regulate expression of intercellular adhesion molecule-1 (ICAM-1) in human bronchial epithelial cells.
Journal: Clinical and experimental immunology 20000501
Title: Inhibition of p38 MAP kinase as a therapeutic strategy.
Journal: Immunopharmacology 20000501
Title: Stimulation of p38 mitogen-activated protein kinase is an early regulatory event for the cadmium-induced apoptosis in human promonocytic cells.
Journal: The Journal of biological chemistry 20000414
Title: Specific role of the extracellular signal-regulated kinase pathway in angiotensin II-induced cardiac hypertrophy in vitro.
Journal: The Biochemical journal 20000401
Title: Deficiency of the stress kinase p38alpha results in embryonic lethality: characterization of the kinase dependence of stress responses of enzyme-deficient embryonic stem cells.
Journal: The Journal of experimental medicine 20000306
Title: ERK signaling mediates the induction of inflammatory cytokines by bufalin in human monocytic cells.
Journal: American journal of physiology. Cell physiology 20000301
Title: Mechanisms of GM-CSF increase by diesel exhaust particles in human airway epithelial cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20000101
Title: Cocaine and apoptosis in myocardial cells.
Journal: The Anatomical record 19991215
Title: Expression and release of chemokines associated with apoptotic cell death in human promonocytic U937 cells and peripheral blood mononuclear cells.
Journal: European journal of immunology 19991001
Title: Cellular stress in xenopus kidney cells enhances the phosphorylation of eukaryotic translation initiation factor (eIF)4E and the association of eIF4F with poly(A)-binding protein.
Journal: The Biochemical journal 19990915
Title: Activation of p38 mitogen-activated protein kinase and caspases in UVB-induced apoptosis of human keratinocyte HaCaT cells.
Journal: The Journal of investigative dermatology 19990501
Title: The p38 mitogen-activated protein kinase cascade is not required for the stimulation of insulin secretion from rat islets of Langerhans.
Journal: Molecular and cellular endocrinology 19990225
Title: Glucose stimulates translocation of the homeodomain transcription factor PDX1 from the cytoplasm to the nucleus in pancreatic beta-cells.
Journal: The Journal of biological chemistry 19990108
Title: Regulation of System A amino acid transport in L6 rat skeletal muscle cells by insulin, chemical and hyperthermic stress.
Journal: FEBS letters 19981211
Title: Differential activation of p38 mitogen-activated protein kinase and extracellular signal-regulated protein kinases confers cadmium-induced HSP70 expression in 9L rat brain tumor cells.
Journal: The Journal of biological chemistry 19981127
Title: Pyrroles and other heterocycles as inhibitors of p38 kinase.
Journal: Bioorganic & medicinal chemistry letters 19981006
Title: The activation state of p38 mitogen-activated protein kinase determines the efficiency of ATP competition for pyridinylimidazole inhibitor binding.
Journal: Biochemistry 19980929
Title: Requirement of p38 mitogen-activated protein kinase for neuronal differentiation in PC12 cells.
Journal: The Journal of biological chemistry 19980918
Title: A comparison of signaling requirements for apoptosis of human B lymphocytes induced by the B cell receptor and CD95/Fas.
Journal: Journal of immunology (Baltimore, Md. : 1950) 19980701
Title: Stress-induced immediate-early gene, egr-1, involves activation of p38/JNK1.
Journal: Oncogene 19980604
Title: Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution.
Journal: Chemistry & biology 19980601
Title: The phosphorylation of eukaryotic initiation factor eIF4E in response to phorbol esters, cell stresses, and cytokines is mediated by distinct MAP kinase pathways.
Journal: The Journal of biological chemistry 19980417
Title: The stress inducer arsenite activates mitogen-activated protein kinases extracellular signal-regulated kinases 1 and 2 via a MAPK kinase 6/p38-dependent pathway.
Journal: The Journal of biological chemistry 19980123
Title: Participation of a stress-activated protein kinase cascade in the activation of tyrosine hydroxylase in chromaffin cells.
Journal: European journal of biochemistry 19970801
Title: Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site.
Journal: The Journal of biological chemistry 19970502
Title: Oxidative and chemical stress mimic insulin by selectively inhibiting the expression of phosphoenolpyruvate carboxykinase in hepatoma cells.
Journal: Diabetes 19970101
Title: Method for preservation of water content during prolonged storage of cerebral tissue.
Journal: Neurological research 19900301
Title: Glucocorticoid rapidly enhances NMDA-evoked neurotoxicity by attenuating the NR2A-containing NMDA receptor-mediated ERK1/2 activation.
Journal: Molecular endocrinology (Baltimore, Md.)
Title: Noncanonical BMP signaling regulates cyclooxygenase-2 transcription.
Journal: Molecular endocrinology (Baltimore, Md.)
