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15291-77-7,MFCD05662347
Catalog No.:AA007J94

15291-77-7 | Ginkgolide b

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5mg
98%(HPLC)
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$43.00   $30.00
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10mg
≥98%
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$69.00   $48.00
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25mg
98%(HPLC)
in stock  
$112.00   $78.00
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50mg
≥98%
in stock  
$219.00   $153.00
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100mg
>93.0%(HPLC)
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$256.00   $180.00
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250mg
98%
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1g
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA007J94
Chemical Name:
Ginkgolide b
CAS Number:
15291-77-7
Molecular Formula:
C20H24O10
Molecular Weight:
424.3986
MDL Number:
MFCD05662347
SMILES:
O=C1OC2C(C1C)(O)C13C4(C2O)C(OC3=O)CC(C24C(O1)OC(=O)C2O)C(C)(C)C
NSC Number:
110257
Properties
Computed Properties
 
Complexity:
925  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
1  
Undefined Atom Stereocenter Count:
11  
XLogP3:
-0.4  

Literature

Title: miR214-regulated p53-NOX4/p66shc pathway plays a crucial role in the protective effect of Ginkgolide B against cisplatin-induced cytotoxicity in HEI-OC1 cells.

Journal: Chemico-biological interactions 20160205

Title: Ginkgolide B protects human umbilical vein endothelial cells against xenobiotic injuries via PXR activation.

Journal: Acta pharmacologica Sinica 20160201

Title: [Ginkgolide B promotes axonal growth of retina ganglion cells by anti-apoptosis in vitro].

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20120825

Title: Complete 1H NMR spectral analysis of ten chemical markers of Ginkgo biloba.

Journal: Magnetic resonance in chemistry : MRC 20120801

Title: Ginkgolide B produced endophytic fungus (Fusarium oxysporum) isolated from Ginkgo biloba.

Journal: Fitoterapia 20120701

Title: In vitro suppression of lymphocyte activation in patients with seasonal allergic rhinitis and pollen-related asthma by cetirizine or azelastine in combination with ginkgolide B or astaxanthin.

Journal: Acta physiologica Hungarica 20120601

Title: Ginkgolide B inhibits renal cyst development in in vitro and in vivo cyst models.

Journal: American journal of physiology. Renal physiology 20120515

Title: Premenstrual syndrome and migraine.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20120501

Title: Different neuroprotective responses of Ginkgolide B and bilobalide, the two Ginkgo components, in ischemic rats with hyperglycemia.

Journal: European journal of pharmacology 20120227

Title: Ginkgo biloba extract attenuates warfarin-mediated anticoagulation through induction of hepatic cytochrome P450 enzymes by bilobalide in mice.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20120115

Title: Ginkgolide B reduces atherogenesis and vascular inflammation in ApoE(-/-) mice.

Journal: PloS one 20120101

Title: Ginkgo may prevent genetic-associated ovarian cancer risk: multiple biomarkers and anticancer pathways induced by ginkgolide B in BRCA1-mutant ovarian epithelial cells.

Journal: European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20111101

Title: Effects of Ginkgo biloba constituents on fruit-infesting behavior of codling moth (Cydia pomonella) in apples.

Journal: Journal of agricultural and food chemistry 20111026

Title: Ginkgolide B attenuates ethanol-induced neurotoxicity through regulating NADPH oxidases.

Journal: Toxicology 20110905

Title: Role of platelet-activating factor in the pathogenesis of 5-fluorouracil-induced intestinal mucositis in mice.

Journal: Cancer chemotherapy and pharmacology 20110901

Title: Effect of ginkgolide B on striatal extracellular amino acids in middle cerebral artery occluded rats.

Journal: Journal of ethnopharmacology 20110614

Title: Ginkgolide B reduces inflammatory protein expression in oxidized low-density lipoprotein-stimulated human vascular endothelial cells.

Journal: Journal of cardiovascular pharmacology 20110601

Title: An efficient molecular docking method for adsorbent screening.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110601

Title: Ginkgolide B promotes proliferation and functional activities of bone marrow-derived endothelial progenitor cells: involvement of Akt/eNOS and MAPK/p38 signaling pathways.

Journal: European cells & materials 20110528

Title: Modulation of CYP1A1 activity by a Ginkgo biloba extract in the human intestinal Caco-2 cells.

Journal: Toxicology letters 20110510

Title: Mechanism and dose-effect of Ginkgolide B on severe acute pancreatitis of rats.

Journal: World journal of gastroenterology 20110507

Title: Ginkgolide B complex efficacy for brief prophylaxis of migraine in school-aged children: an open-label study.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20110201

Title: Ginkgolide B and bilobalide block the pore of the 5-HT₃receptor at a location that overlaps the picrotoxin binding site.

Journal: Neuropharmacology 20110201

Title: Ginkgolide B protects hippocampal neurons from apoptosis induced by beta-amyloid 25-35 partly via up-regulation of brain-derived neurotrophic factor.

Journal: European journal of pharmacology 20101125

Title: Isolation and structure characterization of related impurities in 10-O-(N,N-dimethylaminoethyl)-ginkgolide B methanesulfonate (XQ-1H) bulk drug and quantitation by a validated RP-LC.

Journal: Journal of pharmaceutical and biomedical analysis 20100801

Title: [Extraction, isolation and purification for ginkgolide B].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100801

Title: An innovative approach for migraine prevention in young age: a preliminary study.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20100601

Title: Pharmacokinetics of bilobalide, ginkgolide A and B after administration of three different Ginkgo biloba L. preparations in humans.

Journal: Phytotherapy research : PTR 20100301

Title: [Neuroprotective effect of extract of Ginkgo biloba against excitotoxicty compared with ginkgolide B in neuron cell of rat].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100101

Title: Chemical constituents of the bark of Machilus wangchiana and their biological activities.

Journal: Journal of natural products 20091201

Title: Protective effects of Ginkgo biloba extract (EGb761) and its constituents quercetin and ginkgolide B against beta-amyloid peptide-induced toxicity in SH-SY5Y cells.

Journal: Chemico-biological interactions 20090914

Title: Ginkgolide B induces apoptosis via activation of JNK and p21-activated protein kinase 2 in mouse embryonic stem cells.

Journal: Annals of the New York Academy of Sciences 20090801

Title: Improvement of contractile function in isolated cardiomyocytes from ischemia-reperfusion rats by ginkgolide B pretreatment.

Journal: Journal of cardiovascular pharmacology 20090701

Title: [Effect of cyclosporine A on the pharmacokinetics of ginkgolide B in rats].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20090601

Title: Efficacy of Ginkgolide B in the prophylaxis of migraine with aura.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20090501

Title: Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways.

Journal: Pharmaceutical research 20090401

Title: Induction of mast cell accumulation, histamine release and skin edema by N49 phospholipase A2.

Journal: BMC immunology 20090101

Title: Ginkgolide B preconditioning protects neurons against ischaemia-induced apoptosis.

Journal: Journal of cellular and molecular medicine 20090101

Title: Effects of ginkgolide B on neuronal discharges in paraventricular nucleus of rat hypothalamic slices.

Journal: Neuroscience bulletin 20081201

Title: Therapy for acute pancreatitis with platelet-activating factor receptor antagonists.

Journal: World journal of gastroenterology 20080814

Title: A cardioprotective role for platelet-activating factor through NOS-dependent S-nitrosylation.

Journal: American journal of physiology. Heart and circulatory physiology 20080601

Title: Induction of cytochrome P450s by terpene trilactones and flavonoids of the Ginkgo biloba extract EGb 761 in rats.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20080501

Title: [Optimized preparation of ginkgolides A and B long-circulating solid lipid nanoparticles by central composite design and response surface method].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080501

Title: [The mechanism of inhibition by ginkgolide B on interleukin-8 production induced by 4-hydroxynonenal in bronchial epithelial cells].

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20080501

Title: [Effect of ginkgolide B on plasma levels of interleukin-12 and PAF in severe acute pancreatitis in rats].

Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20080501

Title: Spectroscopic investigation of Ginkgo biloba terpene trilactones and their interaction with amyloid peptide Abeta(25-35).

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080401

Title: Platelet activating factor (PAF) antagonism with ginkgolide B protects the liver against acute injury. importance of controlling the receptor of PAF.

Journal: Digestive diseases and sciences 20080401

Title: Simultaneous determination of ginkgolides A, B, C and bilobalide in plasma by LC-MS/MS and its application to the pharmacokinetic study of Ginkgo biloba extract in rats.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080315

Title: Identification of ginkgolide B metabolites in urine and rat liver cytochrome P450 enzymes responsible for their formation in vitro.

Journal: Acta pharmacologica Sinica 20080301

Title: Ginkgolide B inhibits carotid sinus baroreflex in anesthetized male rats.

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20080225

Title: Induction of cytochrome P450 3A by the Ginkgo biloba extract and bilobalides in human and rat primary hepatocytes.

Journal: Drug metabolism letters 20080101

Title: Effects of Ginkgolide B on 6-OHDA-induced apoptosis and calcium over load in cultured PC12.

Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20071201

Title: Inhibitory effect of ginkgolide B on platelet aggregation in a cAMP- and cGMP-dependent manner by activated MMP-9.

Journal: Journal of biochemistry and molecular biology 20070930

Title: Induction of cyp3a in primary cultures of human hepatocytes by ginkgolides a and B.

Journal: Clinical and experimental pharmacology & physiology 20070701

Title: Ginkgo biloba and ovarian cancer prevention: epidemiological and biological evidence.

Journal: Cancer letters 20070618

Title: [Effects of ginkgolide B against damage of cultured hippocampal neurons caused by glutamate].

Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20070501

Title: Dosage effects of ginkgolide B on ethanol-induced cell death in human hepatoma G2 cells.

Journal: Annals of the New York Academy of Sciences 20070101

Title: Single-laboratory validation for the determination of terpene lactones in Ginkgo biloba dietary supplement crude materials and finished products by high-performance liquid chromatography with evaporative light-scattering detection.

Journal: Journal of AOAC International 20070101

Title: Validation of capillary gas chromatographic method for determination of bilobalide and ginkgolides A, B, C in Ginkgo biloba dry and liquid extracts.

Journal: Acta poloniae pharmaceutica 20070101

Title: Protection by EGb 761 against beta-amyloid-induced neurotoxicity: involvement of NF-kappaB, SIRT1, and MAPKs pathways and inhibition of amyloid fibril formation.

Journal: Free radical biology & medicine 20061215

Title: Interaction of macrophages with apoptotic cells enhances HIV Type 1 replication through PGE2, PAF, and vitronectin receptor.

Journal: AIDS research and human retroviruses 20060801

Title: Cytokine-induced monocyte adhesion to endothelial cells involves platelet-activating factor: suppression by conjugated linoleic acid.

Journal: Biochimica et biophysica acta 20060701

Title: Paradoxical effects of ginkgolide B on cardiomyocyte contractile function in normal and high-glucose environments.

Journal: Acta pharmacologica Sinica 20060501

Title: [The expression of 4-hydroxy-2-nonenal caused by cigarette smoke condensate exposure in human bronchial epithelial cells and the interventional effects of ginkgolide B].

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20060401

Title: Action of beta-amyloid peptide₁₋₄₀ on I(HVA) and its modulation by ginkgolide B.

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20060225

Title: LC-MS characterization of terpene lactones in plasma of experimental animals treated with Ginkgo biloba extracts Correlation with pharmacological activity.

Journal: Journal of pharmaceutical and biomedical analysis 20060224

Title: Effect of increased hepatic platelet activating factor and its receptor portal hypertension in CCl4-induced liver cirrhosis.

Journal: World journal of gastroenterology 20060207

Title: PAF antagonist BN-52021 reduces intercellular adhesion molecule-1 expression and oxidative stress in rats with reperfusion damage due to unilateral testicular torsion.

Journal: Pediatric surgery international 20060201

Title: Effect of platelet-activating factor (PAF) receptor antagonist (BN52021) on acetaminophen-induced acute liver injury and regeneration in rats.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20060201

Title: Sensitive and selective liquid chromatography-electrospray ionization mass spectrometry analysis of ginkgolide B in dog plasma.

Journal: Journal of pharmaceutical and biomedical analysis 20060123

Title: [Influence of platelet activating factor and its antagonist on portal hypertension associated with liver cirrhosis: an experiment with rats].

Journal: Zhonghua yi xue za zhi 20051214

Title: [Quantitative determination of ginkgolides by liquid chromatography-electrospray mass spectrometry].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20051201

Title: The beta subunit increases the ginkgolide B sensitivity of inhibitory glycine receptors.

Journal: Neuropharmacology 20051101

Title: Ginkgolide B stimulates signaling events in neutrophils and primes defense activities.

Journal: Biochemical and biophysical research communications 20051007

Title: Induction of angiogenesis by platelet-activating factor in the rat striatum.

Journal: Neuroreport 20050928

Title: Human resting CD16-, CD16+ and IL-2-, IL-12-, IL-15- or IFN-alpha-activated natural killer cells differentially respond to sphingosylphosphorylcholine, lysophosphatidylcholine and platelet-activating factor.

Journal: European journal of immunology 20050901

Title: Acute subdural hematoma: new model delineation and effects of coagulation inhibitors.

Journal: Neurosurgery 20050901

Title: Effect of bacosides, alcoholic extract of Bacopa monniera Linn. (brahmi), on experimental amnesia in mice.

Journal: Indian journal of experimental biology 20050701

Title: Ginkgolide B, a constituent of Ginkgo biloba, facilitates glutamate exocytosis from rat hippocampal nerve terminals.

Journal: European journal of pharmacology 20050509

Title: Action of aluminum on high voltage-dependent calcium current and its modulation by ginkgolide B.

Journal: Acta pharmacologica Sinica 20050501

Title: [Inhibitory effect of ginkgolide B on angiogenesis in chronic inflammation].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20050401

Title: Platelet-activating factor enhances the expression of nerve growth factor in normal human astrocytes under hypoxia.

Journal: Brain research. Molecular brain research 20050105

Title: [Applications of two-dimensional liquid chromatography coupled to mass spectrometry for the separation and identification of compounds in ginkgo biloba extracts].

Journal: Se pu = Chinese journal of chromatography 20050101

Title: The effect of platelet activating factor antagonist BN 52021 on bacterial translocation and ICAM-I expression in experimental obstructive jaundice.

Journal: Journal of investigative surgery : the official journal of the Academy of Surgical Research 20050101

Title: Anti-apoptotic actions of the platelet-activating factor acetylhydrolase I alpha2 catalytic subunit.

Journal: The Journal of biological chemistry 20041210

Title: Preparation of a tritiated ginkgolide.

Journal: Bioorganic & medicinal chemistry letters 20041115

Title: Isolation of ginkgolides A, B, C, J and bilobalide from G. biloba extracts.

Journal: Phytochemistry 20041101

Title: Association of endothelin with lung hemorrhage induced by immune complexes in rats.

Journal: Inflammation 20041001

Title: Synergistic interaction of endogenous platelet-activating factor and vasopressin in generating angina in rats.

Journal: European journal of pharmacology 20040913

Title: Targeted disruption of PSD-93 gene reduces platelet-activating factor-induced neurotoxicity in cultured cortical neurons.

Journal: Experimental neurology 20040901

Title: Interplay among platelet-activating factor, oxidative stress, and group I metabotropic glutamate receptors modulates neuronal survival.

Journal: Journal of neuroscience research 20040815

Title: A method for extraction and quantification of Ginkgo terpene trilactones.

Journal: Analytical chemistry 20040801

Title: Effect of ginkgolides on beta-amyloid-suppressed acetylocholine release from rat hippocampal slices.

Journal: Phytotherapy research : PTR 20040701

Title: Ginkgolides, diterpene trilactones of Ginkgo biloba, as antagonists at recombinant alpha1beta2gamma2L GABAA receptors.

Journal: European journal of pharmacology 20040628

Title: Determination of ginkgolide A, B, and bilobalide in biloba L. extracts by microdialysis-HPLC.

Journal: Analytical and bioanalytical chemistry 20040601

Title: Increased hepatic platelet activating factor (PAF) and PAF receptors in carbon tetrachloride induced liver cirrhosis.

Journal: Gut 20040601

Title: Ginkgolide B preferentially blocks chloride channels formed by heteromeric glycine receptors in hippocampal pyramidal neurons of rat.

Journal: Brain research bulletin 20040530

Title: Determination of specific receptor sites for platelet activating factor in bovine neutrophils.

Journal: American journal of veterinary research 20040501

Title: [Studies on the cell growth, differentiation and terpene lactone accumulation in Ginkgo biloba cell suspension cultures].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20040501

Title: Identification of the adrenocorticotropin and ginkgolide B-regulated 90-kilodalton protein (p90) in adrenocortical cells as a serotransferrin precursor protein homolog (adrenotransferrin).

Journal: Endocrinology 20040401

Title: [Corneal epithelial wound healing is delayed by platelet activating factor treatment].

Journal: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20040301

Title: Involvement of the NMDA receptor/nitric oxide signal pathway in platelet-activating factor-induced neurotoxicity.

Journal: Neuroreport 20040209

Title: Inhibition of hippocampal LTP by ginkgolide B is mediated by its blocking action on PAF rather than glycine receptors.

Journal: Neurochemistry international 20040201

Title: In vitro effects of astaxanthin combined with ginkgolide B on T lymphocyte activation in peripheral blood mononuclear cells from asthmatic subjects.

Journal: Journal of pharmacological sciences 20040201

Title: Beneficial effects of recombinant platelet-activating factor acetylhydrolase and BN 52021 on bacterial translocation in cerulein-induced pancreatitis.

Journal: European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20040101

Title: An anxiolytic-like effect of Ginkgo biloba extract and its constituent, ginkgolide-A, in mice.

Journal: Journal of natural products 20031001

Title: Role of platelet activating factor in triazolobenzodiazepines-induced retrograde amnesia.

Journal: Behavioural brain research 20030616

Title: Pharmacological studies supporting the therapeutic use of Ginkgo biloba extract for Alzheimer's disease.

Journal: Pharmacopsychiatry 20030601

Title: Pharmacokinetics of Ginkgo biloba extracts.

Journal: Pharmacopsychiatry 20030601

Title: Structure-activity studies with Ginkgo biloba extract constituents as receptor-gated chloride channel blockers and modulators.

Journal: Pharmacopsychiatry 20030601

Title: Neuronal damage by secretory phospholipase A2: modulation by cytosolic phospholipase A2, platelet-activating factor, and cyclooxygenase-2 in neuronal cells in culture.

Journal: Neuroscience letters 20030227

Title: Preparation of 7-substituted ginkgolide derivatives: potent platelet activating factor (PAF) receptor antagonists.

Journal: Journal of medicinal chemistry 20030213

Title: Quantitative analysis of bilobalide and ginkgolides from Ginkgo biloba leaves and Ginkgo products using (1)H-NMR.

Journal: Chemical & pharmaceutical bulletin 20030201

Title: Development and validation of a gas chromatographic-mass spectrometric method for simultaneous identification and quantification of marker compounds including bilobalide, ginkgolides and flavonoids in Ginkgo biloba L. extract and pharmaceutical preparations.

Journal: Journal of chromatography. A 20030131

Title: Homocysteine stimulates inducible nitric oxide synthase expression in macrophages: antagonizing effect of ginkgolides and bilobalide.

Journal: Molecular and cellular biochemistry 20030101

Title: Adrenalectomy-induced cell death in the dentate gyrus: further characterisation using TUNEL and effects of the Ginkgo biloba extract, EGb 761, and ginkgolide B.

Journal: Hippocampus 20030101

Title: The effects of glucose-insulin-potassium solution and BN 52021 in intestinal ischemia-reperfusion injury.

Journal: Vascular and endovascular surgery 20030101

Title: Immediate and delayed VEGF-mediated NO synthesis in endothelial cells: role of PI3K, PKC and PLC pathways.

Journal: British journal of pharmacology 20021201

Title: Evidence for the involvement of a macrophage-derived chemotactic mediator in the neutrophil recruitment induced by staphylococcal enterotoxin B in mice.

Journal: Toxicon : official journal of the International Society on Toxinology 20021201

Title: In vitro effects of ginkgolide B combined with cyclosporin A on T-lymphocyte activation and IL-5 expression in peripheral blood mononuclear cells from asthmatic subjects.

Journal: Transplantation proceedings 20021101

Title: Influence of pharmaceutical quality on the bioavailability of active components from Ginkgo biloba preparations.

Journal: The Journal of pharmacy and pharmacology 20021101

Title: Ginkgolide A, B, and huperzine A inhibit nitric oxide-induced neurotoxicity.

Journal: International immunopharmacology 20021001

Title: Identification and the retention index of bilobalide and ginkgolides using capillary gas chromatography.

Journal: Journal of chromatographic science 20021001

Title: Use of ginkgolide B and a ginkgolide-activated response element to control gene transcription: example of the adrenocortical peripheral-type benzodiazepine receptor.

Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20020901

Title: Ginkgolide derivatives for photolabeling studies: preparation and pharmacological evaluation.

Journal: Journal of medicinal chemistry 20020829

Title: Platelet-activating factor increases prostaglandin E(2) release from astrocyte-enriched cortical cell cultures.

Journal: Brain research 20020809

Title: Antiplatelet aggregation activity of diterpene alkaloids from Spiraea japonica.

Journal: European journal of pharmacology 20020802

Title: Ginkgolides: selective acetylations, translactonization, and biological evaluation.

Journal: The Journal of organic chemistry 20020628

Title: BN52021, a platelet activating factor antagonist, is a selective blocker of glycine-gated chloride channel.

Journal: Neurochemistry international 20020601

Title: Inhibition of intracellular calcium elevation and blunting of vasopressor response due to serotonin by ginkgolide B.

Journal: Planta medica 20020601

Title: Monocyte chemoattractant protein-1 and 5-lipoxygenase products recruit leukocytes in response to platelet-activating factor-like lipids in oxidized low-density lipoprotein.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020415

Title: Sensitization of human neutrophil defense activities through activation of platelet-activating factor receptors by ginkgolide B, a bioactive component of the Ginkgo biloba extract EGB 761.

Journal: Biochemical pharmacology 20020401

Title: Early vascular permeability in murine experimental peritonitis is co-mediated by resident peritoneal macrophages and mast cells: crucial involvement of macrophage-derived cysteinyl-leukotrienes.

Journal: Inflammation 20020401

Title: Selective responses of three Ginkgo biloba leaf-derived constituents on human intestinal bacteria.

Journal: Journal of agricultural and food chemistry 20020327

Title: Three ginkgolide hydrates from Ginkgo biloba L.: ginkgolide A monohydrate, ginkgolide C sesquihydrate and ginkgolide J dihydrate, all determined at 120 K.

Journal: Acta crystallographica. Section C, Crystal structure communications 20020301

Title: Effects of extract of Ginkgo biloba leaves and its constituents on carcinogen-metabolizing enzyme activities and glutathione levels in mouse liver.

Journal: Life sciences 20020222

Title: Effect of the platelet-activating factor antagonist BN-52021 on liver preservation (4 degrees): experimental study in isolated reperfused rat liver model.

Journal: Transplantation proceedings 20020201

Title: [Inhibitory effects of ginkgolide B on proliferation of bovine aortic smooth muscle cells].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20020201

Title: Liquid chromatography-atmospheric pressure chemical ionisation/mass spectrometry: a rapid and selective method for the quantitative determination of ginkgolides and bilobalide in ginkgo leaf extracts and phytopharmaceuticals.

Journal: Phytochemical analysis : PCA 20020101

Title: The central role of thromboxane and platelet activating factor receptors in ex vivo regulation of endotoxin-induced monocyte tissue factor activity in human whole blood.

Journal: Journal of endotoxin research 20020101

Title: Current studies on anti-endotoxic chemical components of traditional Chinese medicine in China.

Journal: Acta pharmacologica Sinica 20011201

Title: Exogenous glutamate induces short and long-term potentiation in the rat medial vestibular nuclei.

Journal: Neuroreport 20010808

Title: Identification of platelet-activating factor as the inflammatory lipid mediator in CCl4-metabolizing rat liver.

Journal: Journal of lipid research 20010401

Title: Inhibition by ginkgolides and bilobalide of the production of nitric oxide in macrophages (THP-1) but not in endothelial cells (HUVEC).

Journal: Biochemical pharmacology 20010215

Title: [Effects of ginkgolide B on arachidonic acid metabolizing enzymes and level of intracellular calcium in rat polymorphonuclear leukocytes].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20010201

Title: Liquid chromatography/atmospheric pressure chemical ionization mass spectrometry of terpene lactones in plasma of volunteers dosed with Ginkgo biloba L. extracts.

Journal: Rapid communications in mass spectrometry : RCM 20010101

Title: Effect of platelet-activating factor antagonists (BN-52021, WEB-2170, and BB-882) on bacterial translocation in acute pancreatitis.

Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20010101

Title: Involvement of nitric oxide in the pathogenesis of cyclophosphamide-induced hemorrhagic cystitis.

Journal: The American journal of pathology 19970101

Title: Formation of LTB4 by fMLP-stimulated alveolar macrophages accounts for eosinophil migration in vitro.

Journal: Journal of leukocyte biology 19920501

Title: Peripheral type benzodiazepine binding sites following transient forebrain ischemia in the rat: effect of neuroprotective drugs.

Journal: Brain research 19911129

Title: Pharmacological modulation of the antigen-induced expression of the low-affinity IgE receptor (Fc epsilon RII/CD23) on rat alveolar macrophages.

Journal: International archives of allergy and applied immunology 19910101

Title: Protective effect of a specific platelet-activating factor antagonist, BN 52021, on bupivacaine-induced cardiovascular impairments in rats.

Journal: Pharmacological research 19890101

Title: Role of platelet-activating factor in adriamycin-induced nephropathy in rats.

Journal: European journal of pharmacology 19870612

Title: Jean R. Rapin, et al. In vitro and in vivo effects of an extract of Ginkgo biloba (EGb 761), ginkgolide B, and bilobalide on apoptosis in primary cultures of rat hippocampal neurons. Drug Development Research, 1998, 45 (1):1-43

Title: Matyas Koltai, et al. Ginkgolide B protects isolated hearts against arrhythmias induced by ischemia but not reperfusion. European Journal of Pharmacology, 1989, 164 (2): 293-302

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Tags:15291-77-7 Molecular Formula|15291-77-7 MDL|15291-77-7 SMILES|15291-77-7 Ginkgolide b