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154709-18-9,MFCD18382355
Catalog No.:AA003AHT

154709-18-9 | 5-[4’-Hydroxymethyl-(1,1’-biphenyl)-2-yl]-1-triphenylmethyltetrazole

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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003AHT
Chemical Name:
5-[4’-Hydroxymethyl-(1,1’-biphenyl)-2-yl]-1-triphenylmethyltetrazole
CAS Number:
154709-18-9
Molecular Formula:
C33H26N4O
Molecular Weight:
494.5857
MDL Number:
MFCD18382355
SMILES:
OCc1ccc(cc1)c1ccccc1c1nnnn1C(c1ccccc1)(c1ccccc1)c1ccccc1
Properties
Computed Properties
 
Complexity:
660  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
38  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
7  
XLogP3:
6.7  

Literature

Title: Yanagihara H, et al. Effects of telmisartan and olmesartan on insulin sensitivity and renal function in spontaneously hypertensive rats fed a high fat diet. J Pharmacol Sci. 2016 Jul;131(3):190-7.

Title: Tanno T, et al. Olmesartan Inhibits Cardiac Hypertrophy in Mice Overexpressing Renin Independently of Blood Pressure: Its Beneficial Effects on ACE2/Ang(1-7)/Mas Axis and NADPH Oxidase Expression. J Cardiovasc Pharmacol. 2016 Jun;67(6):503-9.

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