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1553977-42-6,MFCD28167750
Catalog No.:AA00ABGD

1553977-42-6 | Btk Inhibitor 1 R-Enantiomer Hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
in stock  
$258.00   $180.00
- +
5mg
95%
in stock  
$540.00   $378.00
- +
10mg
95%
in stock  
$772.00   $540.00
- +
50mg
95%
in stock  
$2,315.00   $1,620.00
- +
100mg
95%
in stock  
$3,240.00   $2,268.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00ABGD
Chemical Name:
Btk Inhibitor 1 R-Enantiomer Hydrochloride
CAS Number:
1553977-42-6
Molecular Formula:
C22H23ClN6O
Molecular Weight:
422.9106
MDL Number:
MFCD28167750
SMILES:
Nc1ncnc2c1c(nn2[C@@H]1CCCNC1)c1ccc(cc1)Oc1ccccc1.Cl
Properties
Computed Properties
 
Complexity:
521  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
4  

Literature

Title: Somana Siva Prasad, et al. A QUALITY BY DESIGN APPROACH FOR DEVELOPMENT OF SIMPLE AND ROBUST REVERSED PHASE STABILITY INDICATING HPLC METHOD FOR ESTIMATION OF IBRUTINIB AND ITS IMPURITIES.

Title: Honigberg LA, et al. The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13075-80.

Title: Liu N, et al. Direct and two-step bioorthogonal probes for Bruton's tyrosine kinase based on ibrutinib: a comparative study. Org Biomol Chem. 2015 May 14;13(18):5147-57.

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SDS
Tags:1553977-42-6 Molecular Formula|1553977-42-6 MDL|1553977-42-6 SMILES|1553977-42-6 Btk Inhibitor 1 R-Enantiomer Hydrochloride