Home Sulfonamines 1576-47-2
1576-47-2,MFCD00051931
Catalog No.:AA001PHA

1576-47-2 | 2-Naphthalenesulfonamide

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1g
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$14.00   $10.00
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5g
97%
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA001PHA
Chemical Name:
2-Naphthalenesulfonamide
CAS Number:
1576-47-2
Molecular Formula:
C10H9NO2S
Molecular Weight:
207.2490
MDL Number:
MFCD00051931
SMILES:
NS(=O)(=O)c1ccc2c(c1)cccc2
NSC Number:
31057
Properties
Properties
 
Form:
Solid  
MP:
215-219 °C(lit.)  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
294  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
0.4  

Downstream Synthesis Route

[1]Kasprzycka,Ewa;Trush,VictorA.;Amirkhanov,VladimirM.;Jerzykiewicz,Lucjan;Malta,OscarL.;Legendziewicz,Janina;Gawryszewska,Paula[Chemistry-AEuropeanJournal,2017,vol.23,#6,p.1318-1330]

[2]Kirsanow;Schewtschenko[ZhurnalObshcheiKhimii,1954,vol.24,p.474,482,882,883;engl.Ausg.S.483,490,879,880]

[1]Yee;Bernstein;Adams;Brown;Cronk;Hebbel;Vacek;Krell;Snyder[JournalofMedicinalChemistry,1990,vol.33,#9,p.2437-2451]

[1]Firouzabadi,Habib;Adibi,Mina;Ghadami,Mahboobeh[Phosphorus,SulfurandSiliconandtheRelatedElements,1998,vol.142,p.191-220]

[2]Ranu,BrindabanC.;Sarkar,Arunkanti;Chakraborty,Rupak[JournalofOrganicChemistry,1994,vol.59,#15,p.4114-4116]

[1]Howbert;Grossman;Crowell;Rieder;Harper;Kramer;Tao;Aikins;Poore;Rinzel;Grindey;Shaw;Todd[JournalofMedicinalChemistry,1990,vol.33,#9,p.2393-2407]

[1]Charlton,MichaelH.;Aleksis,Rihards;Saint-Leger,Adélaïde;Gupta,Arya;Loza,Einars;RibasDePouplana,Lluís;Kaula,Ilze;Gustina,Daina;Madre,Marina;Lola,Daina;Jaudzems,Kristaps;Edmund,Grace;Randall,ChristopherP.;Kime,Louise;O'Neill,AlexJ.;Goessens,Wil;Jirgensons,Aigars;Finn,PaulW.[ACSMedicinalChemistryLetters,2018,vol.9,#2,p.84-88]

[2]Kasprzycka,Ewa;Trush,VictorA.;Amirkhanov,VladimirM.;Jerzykiewicz,Lucjan;Malta,OscarL.;Legendziewicz,Janina;Gawryszewska,Paula[Chemistry-AEuropeanJournal,2017,vol.23,#6,p.1318-1330]

[3]Conlon,IvieL.;Drennen,Brandon;Lanning,MaryannaE.;Hughes,Samuel;Rothhaas,Rebecca;Wilder,PaulT.;MacKerell,AlexanderD.;Fletcher,Steven[ChemMedChem,2020,vol.15,#18,p.1691-1698]

[4]Aime,Silvio;Botta,Mauro;Cravotto,Giancarlo;Frullano,Luca;Giovenzana,GiovanniB.;Crich,SimonettaGeninatti;Palmisano,Giovanni;Sisti,Massimo[HelveticaChimicaActa,2005,vol.88,#3,p.588-603]

[5]Mahajan,Anju;Chhabra,SiriRam;Chan,WengC.[TetrahedronLetters,1999,vol.40,#26,p.4909-4912]

[6]CurrentPatentAssignee:GAINTHERAPEUTICS-WO2021/105906,2021,A1Locationinpatent:Page/Pagecolumn120;121

[7]Blas,AndresDe;Santis,GiancarloDe;Fabbrizzi,Luigi;Licchelli,Maurizio;Lanfredi,AnnaMariaManotti;etal.[JournaloftheChemicalSociety,DaltonTransactions,1993,#9,p.1411-1416]

[8]Goodwin,JohnA.;Scheidt,W.Robert[JournalofPhysicalChemistry,1990,vol.94,#11,p.4432-4439]

[9]CurrentPatentAssignee:VANDERBILTUNIVERSITY-WO2014/47427,2014,A2Locationinpatent:Page/Pagecolumn250

[10]Yang,Kai;Ke,Miaolin;Lin,Yuanguang;Song,Qiuling[GreenChemistry,2015,vol.17,#3,p.1395-1399]

[11]Huang,Boshi;Wang,Xueshun;Liu,Xinhao;Chen,Zihui;Li,Wanzhuo;Sun,Songkai;Liu,Huiqing;Daelemans,Dirk;DeClercq,Erik;Pannecouque,Christophe;Zhan,Peng;Liu,Xinyong[BioorganicandMedicinalChemistry,2017,vol.25,#16,p.4397-4406]

[12]Laghezza,Antonio;Piemontese,Luca;Brunetti,Leonardo;Caradonna,Alessia;Agamennone,Mariangela;DiPizio,Antonella;Pochetti,Giorgio;Montanari,Roberta;Capelli,Davide;Tauro,Marilena;Loiodice,Fulvio;Tortorella,Paolo[Pharmaceuticals,2020,vol.13,#6]

[13]Ullah,Saif;El-Gamal,MohammedI.;El-Gamal,Randa;Pelletier,Julie;Sévigny,Jean;Shehata,MahmoudK.;Anbar,HananS.;Iqbal,Jamshed[EuropeanJournalofMedicinalChemistry,2021,vol.217]

[14]Andrews,CharlotteL.;Cardozo,JoaquinM.;Chow,AlyssaS.;Crainic,JenniferA.;Parsons,WilliamH.;Rutland,NicholasT.;Sheehan,BrendanK.[BioorganicandMedicinalChemistryLetters,2021,vol.49]

Literature

Title: Potent and selective 2-naphthylsulfonamide substituted hydroxamic acid inhibitors of matrix metalloproteinase-13.

Journal: Bioorganic & medicinal chemistry letters 20111101

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

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