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161401-82-7,MFCD03452883
Catalog No.:AA001SD0

161401-82-7 | Z-vad-fmk

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1mg
98%
in stock  
$123.00   $86.00
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5mg
≥95%
in stock  
$543.00   $380.00
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10mg
97%
in stock  
$988.00   $692.00
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25mg
97%
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$2,152.00   $1,507.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA001SD0
Chemical Name:
Z-vad-fmk
CAS Number:
161401-82-7
Molecular Formula:
C21H28FN3O7
Molecular Weight:
453.4613
MDL Number:
MFCD03452883
SMILES:
FCC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](C(C)C)NC(=O)OCc1ccccc1)C)CC(=O)O
Properties
Computed Properties
 
Complexity:
680  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
13  
XLogP3:
1.6  

Literature

Title: Isoalantolactone induces apoptosis through reactive oxygen species-dependent upregulation of death receptor 5 in human esophageal cancer cells.

Journal: Toxicology and applied pharmacology 20180801

Title: Doxorubicin triggers bioenergetic failure and p53 activation in mouse stem cell-derived cardiomyocytes.

Journal: Toxicology and applied pharmacology 20180601

Title: Evaluation of cytotoxicity of propofol and its related mechanism in glioblastoma cells and astrocytes.

Journal: Environmental toxicology 20171201

Title: NADPH oxidase inhibitor, diphenyleneiodonium prevents necroptosis in HK-2 cells.

Journal: Biomedical reports 20170901

Title: Mechanical force-mediated pathological cartilage thinning is regulated by necroptosis and apoptosis.

Journal: Osteoarthritis and cartilage 20170801

Title: Nano-sized iron particles may induce multiple pathways of cell death following generation of mistranscripted RNA in human corneal epithelial cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20170801

Title: Quercetin simultaneously induces G(0) /G(1) -phase arrest and caspase-mediated crosstalk between apoptosis and autophagy in human leukemia HL-60 cells.

Journal: Environmental toxicology 20170701

Title: Concomitant epigenetic targeting of LSD1 and HDAC synergistically induces mitochondrial apoptosis in rhabdomyosarcoma cells.

Journal: Cell death & disease 20170601

Title: Nuclear factor erythroid 2-related factor 2 enhances carcinogenesis by suppressing apoptosis and promoting autophagy in nickel-transformed cells.

Journal: The Journal of biological chemistry 20170519

Title: Inhibition of ROS production, autophagy or apoptosis signaling reversed the anticancer properties of Antrodia salmonea in triple-negative breast cancer (MDA-MB-231) cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20170501

Title: Apoptosis inducing factor gene depletion inhibits zearalenone-induced cell death in a goat Leydig cell line.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20170101

Title: Phenolic extract from oleaster (Olea europaea var. Sylvestris) leaves reduces colon cancer growth and induces caspase-dependent apoptosis in colon cancer cells via the mitochondrial apoptotic pathway.

Journal: PloS one 20170101

Title: Role of Cyt-C/caspases-9,3, Bax/Bcl-2 and the FAS death receptor pathway in apoptosis induced by zinc oxide nanoparticles in human aortic endothelial cells and the protective effect by alpha-lipoic acid.

Journal: Chemico-biological interactions 20161025

Title: RSL3 and Erastin differentially regulate redox signaling to promote Smac mimetic-induced cell death.

Journal: Oncotarget 20160927

Title: Critical role of mitochondria-mediated apoptosis for JNJ-26481585-induced antitumor activity in rhabdomyosarcoma.

Journal: Oncogene 20160714

Title: Exogenous H2O2 induces growth inhibition and cell death of human pulmonary artery smooth muscle cells via glutathione depletion.

Journal: Molecular medicine reports 20160701

Title: Smac mimetic sensitizes renal cell carcinoma cells to interferon-α-induced apoptosis.

Journal: Cancer letters 20160528

Title: Cotreatment with Smac mimetics and demethylating agents induces both apoptotic and necroptotic cell death pathways in acute lymphoblastic leukemia cells.

Journal: Cancer letters 20160528

Title: Tetrachlorobenzoquinone Stimulates NLRP3 Inflammasome-Mediated Post-Translational Activation and Secretion of IL-1β in the HUVEC Endothelial Cell Line.

Journal: Chemical research in toxicology 20160321

Title: PARP Inhibitors Sensitize Ewing Sarcoma Cells to Temozolomide-Induced Apoptosis via the Mitochondrial Pathway.

Journal: Molecular cancer therapeutics 20151201

Title: JNJ-26481585 primes rhabdomyosarcoma cells for chemotherapeutics by engaging the mitochondrial pathway of apoptosis.

Journal: Oncotarget 20151110

Title: In vitro evaluation of the anti-apoptotic drug Z-VAD-FMK on human ovarian granulosa cell lines for further use in ovarian tissue transplantation.

Journal: Journal of assisted reproduction and genetics 20151001

Title: Identification of a novel synergistic induction of cell death by Smac mimetic and HDAC inhibitors in acute myeloid leukemia cells.

Journal: Cancer letters 20150928

Title: Cadmium induces apoptosis in primary rat osteoblasts through caspase and mitogen-activated protein kinase pathways.

Journal: Journal of veterinary science 20150901

Title: Smac mimetic and oleanolic acid synergize to induce cell death in human hepatocellular carcinoma cells.

Journal: Cancer letters 20150828

Title: Eribulin synergizes with Polo-like kinase 1 inhibitors to induce apoptosis in rhabdomyosarcoma.

Journal: Cancer letters 20150828

Title: Stimulating basal mitochondrial respiration decreases doxorubicin apoptotic signaling in H9c2 cardiomyoblasts.

Journal: Toxicology 20150806

Title: Combination of cytokinin and auxin induces apoptosis, cell cycle progression arrest and blockage of the Akt pathway in HeLa cells.

Journal: Molecular medicine reports 20150701

Title: Dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 synergizes with chloroquine to induce apoptosis in embryonal rhabdomyosarcoma.

Journal: Cancer letters 20150428

Title: Auranofin induces apoptosis and necrosis in HeLa cells via oxidative stress and glutathione depletion.

Journal: Molecular medicine reports 20150201

Title: Mechanisms underlying 3-bromopyruvate-induced cell death in colon cancer.

Journal: Journal of bioenergetics and biomembranes 20150101

Title: Ectopically expressed sweet pepper ferredoxin PFLP enhances disease resistance to Pectobacterium carotovorum subsp. carotovorum affected by harpin and protease-mediated hypersensitive response in Arabidopsis.

Journal: Molecular plant pathology 20141201

Title: Chemosensitization of rhabdomyosarcoma cells by the histone deacetylase inhibitor SAHA.

Journal: Cancer letters 20140828

Title: The role of RIP3 mediated necroptosis in ouabain-induced spiral ganglion neurons injuries.

Journal: Neuroscience letters 20140822

Title: Quercetin induces apoptosis by inhibiting MAPKs and TRPM7 channels in AGS cells.

Journal: International journal of molecular medicine 20140601

Title: Akt and mTOR mediate programmed necrosis in neurons.

Journal: Cell death & disease 20140201

Title: Matrix metalloproteinase-9 is involved in chronic lymphocytic leukemia cell response to fludarabine and arsenic trioxide.

Journal: PloS one 20140101

Title: Telomelysin shows potent antitumor activity through apoptotic and non-apoptotic cell death in soft tissue sarcoma cells.

Journal: Cancer science 20130901

Title: Smac mimetic and demethylating agents synergistically trigger cell death in acute myeloid leukemia cells and overcome apoptosis resistance by inducing necroptosis.

Journal: Cell death & disease 20130901

Title: Streptococcus pneumoniae ClpP protease induces apoptosis via caspase-independent pathway in human neuroblastoma cells: cytoplasmic relocalization of p53.

Journal: Toxicon : official journal of the International Society on Toxinology 20130801

Title: Aneugenic potential of the anticancer drugs melphalan and chlorambucil. The involvement of apoptosis and chromosome segregation regulating proteins.

Journal: Journal of applied toxicology : JAT 20130701

Title: Substrate and inhibitor-induced dimerization and cooperativity in caspase-1 but not caspase-3.

Journal: The Journal of biological chemistry 20130405

Title: Denbinobin induces human glioblastoma multiforme cell apoptosis through the IKKα-Akt-FKHR signaling cascade.

Journal: European journal of pharmacology 20130105

Title: Cadmium-induced apoptosis in primary rat cerebral cortical neurons culture is mediated by a calcium signaling pathway.

Journal: PloS one 20130101

Title: Apoptosis of K562 leukemia cells by Abnobaviscum F®, a European mistletoe extract.

Journal: Oncology reports 20121201

Title: Dysregulated expression of secretogranin III is involved in neurotoxin-induced dopaminergic neuron apoptosis.

Journal: Journal of neuroscience research 20121201

Title: RIP1-mediated mitochondrial dysfunction and ROS production contributed to tumor necrosis factor alpha-induced L929 cell necroptosis and autophagy.

Journal: International immunopharmacology 20121201

Title: Cysteine cathepsins are not critical for TRAIL- and CD95-induced apoptosis in several human cancer cell lines.

Journal: Biological chemistry 20121201

Title: Proteasome inhibitor interacts synergistically with autophagy inhibitor to suppress proliferation and induce apoptosis in hepatocellular carcinoma.

Journal: Cancer 20121115

Title: Hexane extracts of garlic cloves induce apoptosis through the generation of reactive oxygen species in Hep3B human hepatocarcinoma cells.

Journal: Oncology reports 20121101

Title: A hedgehog survival pathway in 'undead' lipotoxic hepatocytes.

Journal: Journal of hepatology 20121001

Title: Neuron-specific non-classical release of prothymosin alpha: a novel neuroprotective damage-associated molecular patterns.

Journal: Journal of neurochemistry 20121001

Title: Increased differentiation capacity of bone marrow-derived mesenchymal stem cells in aquaporin-5 deficiency.

Journal: Stem cells and development 20120901

Title: Stimulation of platelet apoptosis by peptidoglycan from Staphylococcus aureus 113.

Journal: Apoptosis : an international journal on programmed cell death 20120901

Title: Dual inhibition of canonical and noncanonical NF-κB pathways demonstrates significant antitumor activities in multiple myeloma.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120901

Title: Enhanced cell cycle perturbation and apoptosis mediate the synergistic effects of ST1926 and ATRA in neuroblastoma preclinical models.

Journal: Investigational new drugs 20120801

Title: Early-phase occurrence of K+ and Cl- efflux in addition to Ca 2+ mobilization is a prerequisite to apoptosis in HeLa cells.

Journal: Apoptosis : an international journal on programmed cell death 20120801

Title: Mechanism of Mn(II)-mediated dysregulation of glutamine-glutamate cycle: focus on glutamate turnover.

Journal: Journal of neurochemistry 20120801

Title: Reactive oxygen species-mediated mitochondrial pathway is involved in Baohuoside I-induced apoptosis in human non-small cell lung cancer.

Journal: Chemico-biological interactions 20120730

Title: Induction and mechanism of apoptosis by hydroxycamptothecin in human Tenon's capsule fibroblasts.

Journal: Investigative ophthalmology & visual science 20120724

Title: [Inhibition of elicitation of allergic contact dermatitis by topical use of Z-VAD-FMK, a broad caspase inhibitor: experiment in mice].

Journal: Zhonghua yi xue za zhi 20120724

Title: Polo-like kinase 1, a new therapeutic target in hepatocellular carcinoma.

Journal: World journal of gastroenterology 20120721

Title: COX-2-independent induction of apoptosis by celecoxib and polyamine naphthalimide conjugate mediated by polyamine depression in colorectal cancer cell lines.

Journal: International journal of colorectal disease 20120701

Title: Mild activation of poly(ADP-ribose) polymerase (PARP) is neuroprotective in rat hippocampal slice models of ischemic tolerance.

Journal: The European journal of neuroscience 20120701

Title: Caspase-independent apoptosis induction of quorum-sensing autoinducer analogs against chronic myeloid leukemia K562.

Journal: Investigational new drugs 20120601

Title: A novel synthetic C-1 analogue of 7-deoxypancratistatin induces apoptosis in p53 positive and negative human colorectal cancer cells by targeting the mitochondria: enhancement of activity by tamoxifen.

Journal: Investigational new drugs 20120601

Title: Dysregulation of TNFα-induced necroptotic signaling in chronic lymphocytic leukemia: suppression of CYLD gene by LEF1.

Journal: Leukemia 20120601

Title: Mechanism of apoptotosis induced by ortho-topolin riboside in human hepatoma cell line SMMC-7721.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120601

Title: Synthetic menthyl α/β-(1→6)-diglucopyranosides-induced cell death in human leukemia cells is dependent on caspases.

Journal: Bioorganic & medicinal chemistry letters 20120601

Title: Glutathione regulates caspase-dependent ceramide production and curcumin-induced apoptosis in human leukemic cells.

Journal: Free radical biology & medicine 20120501

Title: Metformin and the mTOR inhibitor everolimus (RAD001) sensitize breast cancer cells to the cytotoxic effect of chemotherapeutic drugs in vitro.

Journal: Anticancer research 20120501

Title: PI3K inhibitor D-116883 is effective in in vitro models of ovarian cancer.

Journal: Anticancer research 20120501

Title: Glycophthalocyanines as photosensitizers for triggering mitotic catastrophe and apoptosis in cancer cells.

Journal: Chemical research in toxicology 20120416

Title: Bortezomib induces apoptosis and growth suppression in human medulloblastoma cells, associated with inhibition of AKT and NF-ĸB signaling, and synergizes with an ERK inhibitor.

Journal: Cancer biology & therapy 20120401

Title: The role of autophagy in human endometrium.

Journal: Biology of reproduction 20120301

Title: Inhibition of caspase mediated apoptosis restores muscle function after crush injury in rat skeletal muscle.

Journal: Apoptosis : an international journal on programmed cell death 20120301

Title: A new mouse mutant of the Cdh23 gene with early-onset hearing loss facilitates evaluation of otoprotection drugs.

Journal: The pharmacogenomics journal 20120201

Title: Astragalus membranaceus lectin (AML) induces caspase-dependent apoptosis in human leukemia cells.

Journal: Cell proliferation 20120201

Title: γ-Secretase-dependent cleavage of E-cadherin by staurosporine in breast cancer cells.

Journal: Cell communication & adhesion 20120201

Title: Caspase cleavage of cytochrome c1 disrupts mitochondrial function and enhances cytochrome c release.

Journal: Cell research 20120101

Title: Electrical stimulation promotes the survival of oligodendrocytes in mixed cortical cultures.

Journal: Journal of neuroscience research 20120101

Title: Coxiella burnetii induces apoptosis during early stage infection via a caspase-independent pathway in human monocytic THP-1 cells.

Journal: PloS one 20120101

Title: Depletion of OLFM4 gene inhibits cell growth and increases sensitization to hydrogen peroxide and tumor necrosis factor-alpha induced-apoptosis in gastric cancer cells.

Journal: Journal of biomedical science 20120101

Title: Oncolytic effects of a novel influenza A virus expressing interleukin-15 from the NS reading frame.

Journal: PloS one 20120101

Title: Apoptosis of epithelial cells and macrophages due to nonpigmented Serratia marcescens strains.

Journal: TheScientificWorldJournal 20120101

Title: Effects of the ethylacetate extract of Orostachys japonicus on induction of apoptosis through the p53-mediated signaling pathway in human gastric cancer cells.

Journal: Biological & pharmaceutical bulletin 20120101

Title: R-roscovitine reduces lung inflammation induced by lipoteichoic acid and Streptococcus pneumoniae.

Journal: Molecular medicine (Cambridge, Mass.) 20120101

Title: NF-κB p65 repression by the sesquiterpene lactone, Helenalin, contributes to the induction of autophagy cell death.

Journal: BMC complementary and alternative medicine 20120101

Title: Combinatorial treatment of DNA and chromatin-modifying drugs cause cell death in human and canine osteosarcoma cell lines.

Journal: PloS one 20120101

Title: mTHPC-based photodynamic therapy induction of autophagy and apoptosis in cultured cells in relation to mitochondria and endoplasmic reticulum stress.

Journal: International journal of oncology 20111201

Title: Mechanism of action of the multikinase inhibitor Foretinib.

Journal: Cell cycle (Georgetown, Tex.) 20111201

Title: Curcumin induces Apaf-1-dependent, p21-mediated caspase activation and apoptosis.

Journal: Cell cycle (Georgetown, Tex.) 20111201

Title: Triterpenoid constituents from the roots of Paeonia rockii ssp. rockii.

Journal: Journal of natural products 20111028

Title: Novel acylated steroidal glycosides from Caralluma tuberculata induce caspase-dependent apoptosis in cancer cells.

Journal: Journal of ethnopharmacology 20111011

Title: The apoptosis inducing effects of Sutherlandia spp. extracts on an oesophageal cancer cell line.

Journal: Journal of ethnopharmacology 20111011

Title: Apoptosis of human cholangiocarcinoma cell lines induced by β-escin through mitochondrial caspase-dependent pathway.

Journal: Phytotherapy research : PTR 20111001

Title: Astragalin heptaacetate-induced cell death in human leukemia cells is dependent on caspases and activates the MAPK pathway.

Journal: Cancer letters 20111001

Title: Effect of a caspase inhibitor, zVADfmk, on the inhibition of breast cancer cells by herpes simplex virus type 1.

Journal: Cancer gene therapy 20111001

Title: Silibinin triggers apoptotic signaling pathways and autophagic survival response in human colon adenocarcinoma cells and their derived metastatic cells.

Journal: Apoptosis : an international journal on programmed cell death 20111001

Title: Bacterial meningitis impairs hippocampal neurogenesis.

Journal: Journal of neuropathology and experimental neurology 20111001

Title: Role of caspase 9 in activation of HTLV-1 LTR expression by DNA damaging agents.

Journal: Cell cycle (Georgetown, Tex.) 20111001

Title: Structure of human caspase-6 in complex with Z-VAD-FMK: New peptide binding mode observed for the non-canonical caspase conformation.

Journal: Bioorganic & medicinal chemistry letters 20110915

Title: Wnt5a plays a crucial role in determining tooth size during murine tooth development.

Journal: Cell and tissue research 20110901

Title: L-kynurenine-induced apoptosis in human NK cells is mediated by reactive oxygen species.

Journal: International immunopharmacology 20110801

Title: Induction of apoptotic cell death by ursolic acid through mitochondrial death pathway and extrinsic death receptor pathway in MDA-MB-231 cells.

Journal: Archives of pharmacal research 20110801

Title: Intracochlear perfusion of leupeptin and z-VAD-FMK: influence of antiapoptotic agents on gunshot-induced hearing loss.

Journal: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20110701

Title: Protective effect of caspase inhibition on compression-induced muscle damage.

Journal: The Journal of physiology 20110701

Title: Cryopreservation of amniotic fluid-derived stem cells using natural cryoprotectants and low concentrations of dimethylsulfoxide.

Journal: Cryobiology 20110601

Title: Lipid-soluble ginseng extract induces apoptosis and G0/G1 cell cycle arrest in NCI-H460 human lung cancer cells.

Journal: Plant foods for human nutrition (Dordrecht, Netherlands) 20110601

Title: The relationship between CD86 and CD54 protein expression and cytotoxicity following stimulation with contact allergen in THP-1 cells.

Journal: The Journal of toxicological sciences 20110601

Title: Selective inhibition of HTLV-1-infected cell proliferation by a novel tetramethylnaphthalene derivative.

Journal: Anticancer research 20110601

Title: Use of an adult rat retinal explant model for screening of potential retinal ganglion cell neuroprotective therapies.

Journal: Investigative ophthalmology & visual science 20110501

Title: Antiapoptotic effects of roscovitine on camptothecin-induced DNA damage in neuroblastoma cells.

Journal: Apoptosis : an international journal on programmed cell death 20110501

Title: Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation.

Journal: Chemico-biological interactions 20110425

Title: Hydrogen peroxide induces Beclin 1-independent autophagic cell death by suppressing the mTOR pathway via promoting the ubiquitination and degradation of Rheb in GSH-depleted RAW 264.7 cells.

Journal: Free radical research 20110401

Title: An apoptosis targeted stimulus with nanosecond pulsed electric fields (nsPEFs) in E4 squamous cell carcinoma.

Journal: Apoptosis : an international journal on programmed cell death 20110401

Title: Osteoblast interactions within a biomimetic apatite microenvironment.

Journal: Annals of biomedical engineering 20110401

Title: Light- and sodium azide-induced death of RGC-5 cells in culture occurs via different mechanisms.

Journal: Apoptosis : an international journal on programmed cell death 20110401

Title: Radiosensitization of head and neck squamous cell carcinoma by a SMAC-mimetic compound, SM-164, requires activation of caspases.

Journal: Molecular cancer therapeutics 20110401

Title: Protein phosphatase 1-dependent dephosphorylation of Akt is the prime signaling event in sphingosine-induced apoptosis in Jurkat cells.

Journal: Journal of cellular biochemistry 20110401

Title: Benzo[c]phenanthridine alkaloids exhibit strong anti-proliferative activity in malignant melanoma cells regardless of their p53 status.

Journal: Journal of dermatological science 20110401

Title: Induction of programmed cell death by inhibition of AKT with the alkylphosphocholine perifosine in in vitro models of platinum sensitive and resistant ovarian cancers.

Journal: Archives of gynecology and obstetrics 20110301

Title: Cellular changes in hepatocytes and intestinal endothelium after hepatoduodenal ligament occlusion and protective effects of caspase inhibition.

Journal: Annals of surgery 20110301

Title: Caspase 3 blocking avoids the expression of autoantigens triggered by apoptosis in neonatal Balb/c mice skin.

Journal: Reumatismo 20110301

Title: Ginsenoside Rh2 induces apoptosis and paraptosis-like cell death in colorectal cancer cells through activation of p53.

Journal: Cancer letters 20110227

Title: Gambogic acid enhances proteasome inhibitor-induced anticancer activity.

Journal: Cancer letters 20110227

Title: In vitro effect of different mediators of apoptosis on canine cranial and caudal cruciate ligament fibroblasts and its reversibility by pancaspase inhibitor zVAD.fmk.

Journal: Veterinary immunology and immunopathology 20110215

Title: The release of high mobility group box 1 in apoptosis is triggered by nucleosomal DNA fragmentation.

Journal: Archives of biochemistry and biophysics 20110215

Title: Mitochondrially targeted ceramides preferentially promote autophagy, retard cell growth, and induce apoptosis.

Journal: Journal of lipid research 20110201

Title: Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism.

Journal: Apoptosis : an international journal on programmed cell death 20110201

Title: zVAD-induced necroptosis in L929 cells depends on autocrine production of TNFα mediated by the PKC-MAPKs-AP-1 pathway.

Journal: Cell death and differentiation 20110101

Title: Chikungunya virus mobilizes the apoptotic machinery to invade host cell defenses.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110101

Title: Costunolide induces apoptosis in human endometriotic cells through inhibition of the prosurvival Akt and nuclear factor kappa B signaling pathway.

Journal: Biological & pharmaceutical bulletin 20110101

Title: Bim-mediated apoptosis and PD-1/PD-L1 pathway impair reactivity of PD1(+)/CD127(-) HCV-specific CD8(+) cells targeting the virus in chronic hepatitis C virus infection.

Journal: Cellular immunology 20110101

Title: Gene-specific differential response to anti-apoptotic therapies in zebrafish models of ocular coloboma.

Journal: Molecular vision 20110101

Title: Subarachnoid hemorrhage causes pulmonary endothelial cell apoptosis and neurogenic pulmonary edema in mice.

Journal: Acta neurochirurgica. Supplement 20110101

Title: Proliferation-attenuating and apoptosis-inducing effects of tryptanthrin on human chronic myeloid leukemia K562 cell line in vitro.

Journal: International journal of molecular sciences 20110101

Title: Plasmodium falciparum metacaspase PfMCA-1 triggers a z-VAD-fmk inhibitable protease to promote cell death.

Journal: PloS one 20110101

Title: Induction of caspase-3-dependent apoptosis in human leukemia HL-60 cells by δ-elemene.

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110101

Title: Overexpression of hematopoietically expressed homeoprotein induces nonapoptotic cell death in mouse prechondrogenic ATDC5 cells.

Journal: Biological & pharmaceutical bulletin 20110101

Title: 1,4-Diselenophene-1,4-diketone triggers caspase-dependent apoptosis in human melanoma A375 cells through induction of mitochondrial dysfunction.

Journal: Chemical & pharmaceutical bulletin 20110101

Title: TNFα-induced necroptosis and autophagy via supression of the p38-NF-κB survival pathway in L929 cells.

Journal: Journal of pharmacological sciences 20110101

Title: Pathological and ultrastructural changes in cultured cells induced by venom from the ectoparasitic wasp Nasonia vitripennis (Walker) (Hymenoptera: Pteromalidae).

Journal: Journal of insect physiology 20101201

Title: Cyclophilin A release as a biomarker of necrotic cell death.

Journal: Cell death and differentiation 20101201

Title: Astrocyte-derived glutathione attenuates hemin-induced apoptosis in cerebral microvascular cells.

Journal: Glia 20101115

Title: Pseudomonas exotoxin kills Drosophila S2 cells via apoptosis.

Journal: Toxicon : official journal of the International Society on Toxinology 20101101

Title: NF-kappaB regulates the expression of Nucling, a novel apoptosis regulator, with involvement of proteasome and caspase for its degradation.

Journal: Journal of biochemistry 20101101

Title: Caspase activation is not required for villous cytotrophoblast fusion into syncytiotrophoblasts.

Journal: Placenta 20101101

Title: Human NK cells require caspases for activation-induced proliferation and cytokine release but not for cytotoxicity.

Journal: Scandinavian journal of immunology 20101101

Title: Amiloride derivatives modulate PS externalization in neutrophil-like PLB-985 cells.

Journal: Biochemical pharmacology 20101001

Title: 5-fluorouracil-induced death of Jurkat T-cells--a role for caspases and MCL-1.

Journal: Anticancer research 20101001

Title: γδ T lymphocytes kill T regulatory cells through CD1d.

Journal: Immunology 20101001

Title: Mutant PIK3CA licenses TRAIL and CD95L to induce non-apoptotic caspase-8-mediated ROCK activation.

Journal: Cell death and differentiation 20100901

Title: Preclinical and clinical estimates of the basal apoptotic rate of a cancer predict the amount of apoptosis induced by subsequent proapoptotic stimuli.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100901

Title: Tanshinone IIA inhibits Hep-J5 cells by increasing calreticulin, caspase 12 and GADD153 protein expression.

Journal: International journal of molecular medicine 20100901

Title: Cathepsin B-like and cell death in the unicellular human pathogen Leishmania.

Journal: Cell death & disease 20100901

Title: Cytotoxic T-lymphocytes secrete soluble factors that induce caspase-mediated apoptosis in glioblastoma cell lines.

Journal: Journal of neuroimmunology 20100825

Title: Regulation of GSK-3beta by calpain in the 3-nitropropionic acid model.

Journal: Hippocampus 20100801

Title: Apoptosis as a host defense mechanism in Crassostrea virginica and its modulation by Perkinsus marinus.

Journal: Fish & shellfish immunology 20100801

Title: Silencing of Nuclear Mitotic Apparatus protein (NuMA) accelerates the apoptotic disintegration of the nucleus.

Journal: Apoptosis : an international journal on programmed cell death 20100801

Title: Goniothalamin induces coronary artery smooth muscle cells apoptosis: the p53-dependent caspase-2 activation pathway.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100801

Title: N,N-Dimethyl phytosphingosine sensitizes HL-60/MX2, a multidrug-resistant variant of HL-60 cells, to doxorubicin-induced cytotoxicity through ROS-mediated release of cytochrome c and AIF.

Journal: Apoptosis : an international journal on programmed cell death 20100801

Title: Anti-apoptotic factor z-Val-Ala-Asp-fluoromethylketone promotes the survival of cochlear hair cells in a mouse model for human deafness.

Journal: Neuroscience 20100714

Title: Arsenic trioxide and ascorbic acid demonstrate promising activity against primary human CLL cells in vitro.

Journal: Leukemia research 20100701

Title: Toxicity of Flow Line, Durafill VS, and Dycal to dental pulp cells: effects of growth factors.

Journal: Journal of endodontics 20100701

Title: Carbonyl cyanide p-(trifluoromethoxy) phenylhydroazone induces caspase-independent apoptosis in As4.1 juxtaglomerular cells.

Journal: Anticancer research 20100701

Title: Oxidative stress is important in the pathogenesis of liver injury induced by sulindac and lipopolysaccharide cotreatment.

Journal: Toxicology 20100604

Title: The novel proapoptotic activity of nonnatural enantiomer of Lentiginosine.

Journal: Glycobiology 20100501

Title: Differential role of cathepsins B and L in autophagy-associated cell death induced by arsenic trioxide in U87 human glioblastoma cells.

Journal: Biological chemistry 20100501

Title: Curcumin induces mitochondria pathway mediated cell apoptosis in A549 lung adenocarcinoma cells.

Journal: Oncology reports 20100501

Title: Activation of caspases and apoptosis in response to low-voltage electric pulses.

Journal: Oncology reports 20100501

Title: TNF-alpha reduces the Na+/K+ ATPase activity in LLC-PK1 cells by activating caspases and JNK and inhibiting NF-kappaB.

Journal: Cell biology international 20100427

Title: Erythropoietin suppresses epithelial to mesenchymal transition and intercepts Smad signal transduction through a MEK-dependent mechanism in pig kidney (LLC-PK1) cell lines.

Journal: Experimental cell research 20100415

Title: Caspase-7 cleavage of Kaposi sarcoma-associated herpesvirus ORF57 confers a cellular function against viral lytic gene expression.

Journal: The Journal of biological chemistry 20100409

Title: Caspase inhibitor ZVAD-fmk facilitates engraftment of donor hematopoietic stem cells in intra-bone marrow-bone marrow transplantation.

Journal: Stem cells and development 20100401

Title: Caspase-mediated inhibition of sphingomyelin synthesis is involved in FasL-triggered cell death.

Journal: Cell death and differentiation 20100401

Title: Involvement of caspase activation in azaspiracid-induced neurotoxicity in neocortical neurons.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100401

Title: Different activation forms of MMP-2 oppositely affect the fate of endothelial cells.

Journal: American journal of physiology. Cell physiology 20100401

Title: The mitochondrial serine protease HtrA2/Omi cleaves RIP1 during apoptosis of Ba/F3 cells induced by growth factor withdrawal.

Journal: Cell research 20100401

Title: Mechanisms of chlorpyrifos and diazinon induced neurotoxicity in cortical culture.

Journal: Neuroscience 20100331

Title: Signaling pathway underlying the up-regulatory effect of TNF-alpha on the Na(+)/K(+) ATPase in HepG2 cells.

Journal: Cytokine 20100301

Title: [Apoptosis inducing factor mediates cisplatin-induced apoptosis of renal tubular epithelial cells].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20100301

Title: Noxa is necessary for hydrogen peroxide-induced caspase-dependent cell death.

Journal: FEBS letters 20100219

Title: The role of apoptosis in LDL transport through cultured endothelial cell monolayers.

Journal: Atherosclerosis 20100201

Title: Apoptosis in Candida biofilms exposed to amphotericin B.

Journal: Journal of medical microbiology 20100201

Title: Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation.

Journal: Cancer research 20100201

Title: 2'-epi-2'-O-Acetylthevetin B extracted from seeds of Cerbera manghas L. induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.

Journal: Chemico-biological interactions 20100105

Title: Role of AIF in cardiac apoptosis in hypertrophic cardiomyocytes from Dahl salt-sensitive rats.

Journal: Cardiovascular research 20100101

Title: Functional and structural alterations in the endoplasmic reticulum and mitochondria during apoptosis triggered by C2-ceramide and CD95/APO-1/FAS receptor stimulation.

Journal: Biochemical and biophysical research communications 20100101

Title: Sodium nitroprusside induces autophagic cell death in glutathione-depleted osteoblasts.

Journal: Journal of biochemical and molecular toxicology 20100101

Title: P-Glycoprotein is not a key target for the chemosensitizing effect of 1-phenyl-2-decanoylamino-3-morpholino-1-propanol in HepG2 cells exposed to doxorubicin.

Journal: Drug metabolism letters 20100101

Title: Life-giving caspases: revealing new roles during mouse embryo preimplantation development.

Journal: The International journal of developmental biology 20100101

Title: Effects of small interfering RNAs targeting fascin on human esophageal squamous cell carcinoma cell lines.

Journal: Diagnostic pathology 20100101

Title: Expansion of cord blood CD34 cells in presence of zVADfmk and zLLYfmk improved their in vitro functionality and in vivo engraftment in NOD/SCID mouse.

Journal: PloS one 20100101

Title: Advanced glycation end products induce T cell apoptosis: Involvement of oxidative stress, caspase and the mitochondrial pathway.

Journal: Mechanisms of ageing and development 20100101

Title: Caspase-10-dependent cell death in Fas/CD95 signalling is not abrogated by caspase inhibitor zVAD-fmk.

Journal: PloS one 20100101

Title: 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induce autophagic cell death in estrogen receptor negative breast cancer.

Journal: BMC cancer 20100101

Title: Stochastic competition between mechanistically independent slippage and death pathways determines cell fate during mitotic arrest.

Journal: PloS one 20100101

Title: Preventing Ataxin-3 protein cleavage mitigates degeneration in a Drosophila model of SCA3.

Journal: Human molecular genetics 20091215

Title: Synergistic antiproliferative effect of mTOR inhibitors in combination with 5-fluorouracil in scirrhous gastric cancer.

Journal: Cancer science 20091201

Title: Internalization of NK cells into tumor cells requires ezrin and leads to programmed cell-in-cell death.

Journal: Cell research 20091201

Title: Caspase-1 inhibitor prevents neurogenic pulmonary edema after subarachnoid hemorrhage in mice.

Journal: Stroke 20091201

Title: Oligomerized tumor necrosis factor-related apoptosis inducing ligand strongly induces cell death in myeloma cells, but also activates proinflammatory signaling pathways.

Journal: The FEBS journal 20091201

Title: Feedback regulation of mitochondria by caspase-9 in the B cell receptor-mediated apoptosis.

Journal: Scandinavian journal of immunology 20091201

Title: Involvement of Fractin in TGF-beta-induced apoptosis in oligodendroglial progenitor cells.

Journal: Glia 20091115

Title: Recombinant YopJ induces apoptosis in murine peritoneal macrophages in vitro: involvement of mitochondrial death pathway.

Journal: International immunology 20091101

Title: The coffee diterpene kahweol induces apoptosis in human leukemia U937 cells through down-regulation of Akt phosphorylation and activation of JNK.

Journal: Apoptosis : an international journal on programmed cell death 20091101

Title: Autophagic and apoptotic mechanisms of curcumin-induced death in K562 cells.

Journal: Journal of Asian natural products research 20091101

Title: Vanadium induces dopaminergic neurotoxicity via protein kinase Cdelta dependent oxidative signaling mechanisms: relevance to etiopathogenesis of Parkinson's disease.

Journal: Toxicology and applied pharmacology 20091015

Title: Role of the nanos homolog during sea urchin development.

Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20091001

Title: Mitochondrial-dependent caspase activation pathway is involved in baicalein-induced apoptosis in human hepatoma J5 cells.

Journal: International journal of oncology 20091001

Title: Xanthohumol activates the proapoptotic arm of the unfolded protein response in chronic lymphocytic leukemia.

Journal: Anticancer research 20091001

Title: Endonucleases induced TRAIL-insensitive apoptosis in ovarian carcinoma cells.

Journal: Experimental cell research 20090910

Title: The anti-apoptotic effects of caspase inhibitors on propyl gallate-treated HeLa cells in relation to reactive oxygen species and glutathione levels.

Journal: Archives of toxicology 20090901

Title: Mitochondrial membrane potential disruption pattern in human sperm.

Journal: Human reproduction (Oxford, England) 20090901

Title: Dual mechanisms of sHA 14-1 in inducing cell death through endoplasmic reticulum and mitochondria.

Journal: Molecular pharmacology 20090901

Title: Live-cell imaging of caspase activation for high-content screening.

Journal: Journal of biomolecular screening 20090901

Title: Involvement of caspase-8, -9, and -3 in high glucose-induced apoptosis in PC12 cells.

Journal: Neuroscience letters 20090807

Title: Oxidative stress induction by T-2 toxin causes DNA damage and triggers apoptosis via caspase pathway in human cervical cancer cells.

Journal: Toxicology 20090803

Title: Tubulin inhibitor AEZS 112 inhibits the growth of experimental human ovarian and endometrial cancers irrespective of caspase inhibition.

Journal: Oncology reports 20090801

Title: Caspase inhibitors for the treatment of hepatitis C.

Journal: Clinics in liver disease 20090801

Title: RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis.

Journal: Science (New York, N.Y.) 20090717

Title: Enhanced tissue integration during cartilage repair in vitro can be achieved by inhibiting chondrocyte death at the wound edge.

Journal: Tissue engineering. Part A 20090701

Title: Monocytic differentiation of leukemic HL-60 cells induced by co-treatment with TNF-alpha and MK886 requires activation of pro-apoptotic machinery.

Journal: European journal of haematology 20090701

Title: Ordering of caspases in cells undergoing apoptosis by the intrinsic pathway.

Journal: Cell death and differentiation 20090701

Title: Kidney ischemia-reperfusion injury induces caspase-dependent pulmonary apoptosis.

Journal: American journal of physiology. Renal physiology 20090701

Title: Cadmium exposure induces mitochondria-dependent apoptosis in oligodendrocytes.

Journal: Neurotoxicology 20090701

Title: Proteasome inhibitor MG-132 mediated expression of p27Kip1 via S-phase kinase protein 2 degradation induces cell cycle coupled apoptosis in primary effusion lymphoma cells.

Journal: Leukemia & lymphoma 20090701

Title: Is caspase inhibition a valid therapeutic strategy in cryopreservation of ovarian tissue?

Journal: Journal of assisted reproduction and genetics 20090701

Title: Phosphothioated oligodeoxynucleotides induce nonspecific effects on neuronal cell adhesion in a growth substrate-dependent manner.

Journal: Journal of neuroscience research 20090601

Title: Apoptosis induced by enniatins H and MK1688 isolated from Fusarium oxysporum FB1501.

Journal: Toxicon : official journal of the International Society on Toxinology 20090601

Title: Antiproliferative effects of lactic acid via the induction of apoptosis and cell cycle arrest in a human keratinocyte cell line (HaCaT).

Journal: Journal of dermatological science 20090601

Title: Inducible over-expression of wild type alpha-synuclein in human neuronal cells leads to caspase-dependent non-apoptotic death.

Journal: Journal of neurochemistry 20090601

Title: JNK and p38 MAPK are independently involved in tributyltin-mediated cell death in rainbow trout (Oncorhynchus mykiss) RTG-2 cells.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20090501

Title: Insufficiency of pro-heparin-binding epidermal growth factor-like growth factor shedding enhances hypoxic cell death in H9c2 cardiomyoblasts via the activation of caspase-3 and c-Jun N-terminal kinase.

Journal: The Journal of biological chemistry 20090501

Title: Penta-O-galloyl-beta-D-glucose induces S- and G(1)-cell cycle arrests in prostate cancer cells targeting DNA replication and cyclin D1.

Journal: Carcinogenesis 20090501

Title: Evidence for programmed cell death and activation of specific caspase-like enzymes in the tomato fruit heat stress response.

Journal: Planta 20090501

Title: Radiosensitization of solid tumors by Z-VAD, a pan-caspase inhibitor.

Journal: Molecular cancer therapeutics 20090501

Title: Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells.

Journal: The Journal of clinical investigation 20090501

Title: Cells induced to undergo apo in the presence of the caspase inhibitor benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone stimulate Mo derived phagocytes to secrete proinflammatory cytokines.

Journal: Autoimmunity 20090501

Title: Ibuprofen augments bilirubin toxicity in rat cortical neuronal culture.

Journal: Pediatric research 20090401

Title: Autophagy in coxsackievirus-infected neurons.

Journal: Autophagy 20090401

Title: Enhancement of antitumor properties of rhTRAIL by affinity increase toward its death receptors.

Journal: Biochemistry 20090317

Title: Tumor-derived microvesicles in sera of patients with head and neck cancer and their role in tumor progression.

Journal: Head & neck 20090301

Title: Reactive oxygen species are involved in FasL-induced caspase-independent cell death and inflammatory responses.

Journal: Free radical biology & medicine 20090301

Title: Sanguinarine induces apoptosis in A549 human lung cancer cells primarily via cellular glutathione depletion.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20090301

Title: The HIV protease inhibitor saquinavir induces endoplasmic reticulum stress, autophagy, and apoptosis in ovarian cancer cells.

Journal: Gynecologic oncology 20090301

Title: Brazilian marine sponge Polymastia janeirensis induces apoptotic cell death in human U138MG glioma cell line, but not in a normal cell culture.

Journal: Investigational new drugs 20090201

Title: Platonin induces autophagy-associated cell death in human leukemia cells.

Journal: Autophagy 20090201

Title: The role of P-glycoprotein/cellular prion protein interaction in multidrug-resistant breast cancer cells treated with paclitaxel.

Journal: Cellular and molecular life sciences : CMLS 20090201

Title: A chemical inhibitor of Apaf-1 exerts mitochondrioprotective functions and interferes with the intra-S-phase DNA damage checkpoint.

Journal: Apoptosis : an international journal on programmed cell death 20090201

Title: Astilbotriterpenic acid induces growth arrest and apoptosis in HeLa cells through mitochondria-related pathways and reactive oxygen species (ROS) production.

Journal: Chemistry & biodiversity 20090201

Title: Differential roles for Bak in Triton X-100- and deoxycholate-induced apoptosis.

Journal: Biochemical and biophysical research communications 20090116

Title: Mechanisms of clofibrate-induced apoptosis in Yoshida AH-130 hepatoma cells.

Journal: Biochemical pharmacology 20090115

Title: Possible involvement of caspase-6 and -7 but not caspase-3 in the regulation of hypoxia-induced apoptosis in tube-forming endothelial cells.

Journal: Experimental cell research 20090115

Title: Post-translational modification of cyclin A1 is associated with staurosporine and TNFalpha induced apoptosis in leukemic cells.

Journal: Molecular and cellular biochemistry 20090101

Title: Apoptosis is not required for acantholysis in pemphigus vulgaris.

Journal: American journal of physiology. Cell physiology 20090101

Title: Caspase-independent cell death without generation of reactive oxygen species in irradiated MOLT-4 human leukemia cells.

Journal: Cellular immunology 20090101

Title: Effect of polyI:C cotreatment on halothane-induced liver injury in mice.

Journal: Hepatology (Baltimore, Md.) 20090101

Title: 3-Oxoolean-12-en-27-oic acid isolated from Aceriphyllum rossii induces caspase-8-dependent apoptosis in human promyelocytic leukemia HL-60 cells.

Journal: Biological & pharmaceutical bulletin 20090101

Title: Mode of cytotoxic action of T cell-engaging BiTE antibody MT110.

Journal: Immunobiology 20090101

Title: Dihydroartemisinin (DHA) induces caspase-3-dependent apoptosis in human lung adenocarcinoma ASTC-a-1 cells.

Journal: Journal of biomedical science 20090101

Title: Docetaxel-induced prostate cancer cell death involves concomitant activation of caspase and lysosomal pathways and is attenuated by LEDGF/p75.

Journal: Molecular cancer 20090101

Title: Pretreatment with pancaspase inhibitor (Z-VAD-FMK) delays but does not prevent intraperitoneal heat-killed group B Streptococcus-induced preterm delivery in a pregnant mouse model.

Journal: Infectious diseases in obstetrics and gynecology 20090101

Title: Apoptosis-dependent acute pulmonary injury after intratracheal instillation of angiotensin II.

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20081225

Title: Mechanism of patulin-induced apoptosis in human leukemia cells (HL-60).

Journal: Toxicology letters 20081215

Title: [Attenuation of allergic contact dermatitis by Z-VAD-FMK, a broad caspase inhibitor: experiment with mice].

Journal: Zhonghua yi xue za zhi 20081202

Title: Caspase inhibitor zVAD.fmk reduces infarct size after myocardial ischaemia and reperfusion in rats but not in mice.

Journal: Resuscitation 20081201

Title: Improvement in the in vitro maturation rate of porcine oocytes vitrified at the germinal vesicle stage by treatment with a mitochondrial permeability transition inhibitor.

Journal: Cryobiology 20081201

Title: 4-arylcoumarin analogues of combretastatins stimulate apoptosis of leukemic cells from chronic lymphocytic leukemia patients.

Journal: Experimental hematology 20081201

Title: Caspase-2(L), caspase-9, and caspase-3 during in vitro maturation and fragmentation of the mouse oocyte.

Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20081201

Title: Human telomerase reverse transcriptase (hTERT): a target molecule for the treatment of cisplatin-resistant tumors.

Journal: The Korean journal of laboratory medicine 20081201

Title: PRIMA-1MET induces mitochondrial apoptosis through activation of caspase-2.

Journal: Oncogene 20081120

Title: Rapid reactive oxygen species (ROS) generation induced by curcumin leads to caspase-dependent and -independent apoptosis in L929 cells.

Journal: Free radical biology & medicine 20081115

Title: Dihydrocapsaicin (DHC), a saturated structural analog of capsaicin, induces autophagy in human cancer cells in a catalase-regulated manner.

Journal: Autophagy 20081101

Title: Opposing roles for caspase and calpain death proteases in L-glutamate-induced oxidative neurotoxicity.

Journal: Toxicology and applied pharmacology 20081015

Title: ATP depletion alters the mode of cell death induced by benzyl isothiocyanate.

Journal: Biochimica et biophysica acta 20081001

Title: Oxygen radical induced gastric mucosal cell death: apoptosis or necrosis?

Journal: Digestive diseases and sciences 20080901

Title: Gossypol, a BH3 mimetic, induces apoptosis in chronic lymphocytic leukemia cells.

Journal: Blood 20080901

Title: Enzastaurin-induced apoptosis in glioma cells is caspase-dependent and inhibited by BCL-XL.

Journal: Journal of neurochemistry 20080901

Title: Caspase inhibition augmented oridonin-induced cell death in murine fibrosarcoma l929 by enhancing reactive oxygen species generation.

Journal: Journal of pharmacological sciences 20080901

Title: Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways.

Journal: Autophagy 20080801

Title: Phosphatidylinositol 3-kinase inhibition broadly sensitizes glioblastoma cells to death receptor- and drug-induced apoptosis.

Journal: Cancer research 20080801

Title: 1-Nitropyrene (1-NP) induces apoptosis and apparently a non-apoptotic programmed cell death (paraptosis) in Hepa1c1c7 cells.

Journal: Toxicology and applied pharmacology 20080715

Title: HSP72 attenuates renal tubular cell apoptosis and interstitial fibrosis in obstructive nephropathy.

Journal: American journal of physiology. Renal physiology 20080701

Title: IFNalpha and IFNlambda differ in their antiproliferative effects and duration of JAK/STAT signaling activity.

Journal: Cancer biology & therapy 20080701

Title: ABD56 causes osteoclast apoptosis by inhibiting the NFkappaB and ERK pathways.

Journal: Biochemical and biophysical research communications 20080620

Title: Study of apoptosis-related markers in ram spermatozoa.

Journal: Animal reproduction science 20080601

Title: Impact of Bacillus thuringiensis toxin Cry1Ab on rumen epithelial cells (REC) - a new in vitro model for safety assessment of recombinant food compounds.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080601

Title: Increased inorganic phosphate induces human endothelial cell apoptosis in vitro.

Journal: American journal of physiology. Renal physiology 20080601

Title: Role of cathepsins in blastocyst hatching in the golden hamster.

Journal: Molecular human reproduction 20080601

Title: The characteristic of an anti-human DR5 antibody A6.

Journal: Cellular & molecular immunology 20080601

Title: Autophagic cell death unraveled: Pharmacological inhibition of apoptosis and autophagy enables necrosis.

Journal: Autophagy 20080516

Title: Combinatorial action of the HDAC inhibitor trichostatin A and etoposide induces caspase-mediated AIF-dependent apoptotic cell death in non-small cell lung carcinoma cells.

Journal: Oncogene 20080515

Title: Requirement of caspases and p38 MAPK for TRAIL-mediated ICAM-1 expression by human astroglial cells.

Journal: Immunology letters 20080515

Title: Flavopiridol-induced iNOS downregulation during apoptosis of chronic lymphocytic leukemia cells is caspase-dependent.

Journal: Leukemia research 20080501

Title: Apoptosis seems to be the major process while surface and neural ectodermal layers detach during neurulation.

Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20080501

Title: Autophagy plays a protective role during zVAD-induced necrotic cell death.

Journal: Autophagy 20080501

Title: A novel paradigm for rapid ABT-737-induced apoptosis involving outer mitochondrial membrane rupture in primary leukemia and lymphoma cells.

Journal: Cell death and differentiation 20080501

Title: The death of ouabain-treated renal epithelial cells: evidence against anoikis occurrence.

Journal: Apoptosis : an international journal on programmed cell death 20080501

Title: Trifolin acetate-induced cell death in human leukemia cells is dependent on caspase-6 and activates the MAPK pathway.

Journal: Apoptosis : an international journal on programmed cell death 20080501

Title: Caspase-related apoptosis in chronic ischaemic microangiopathy following experimental vein occlusion in mini-pigs.

Journal: Acta ophthalmologica 20080501

Title: 7-Ketocholesterol activates caspases-3/7, -8, and -12 in human microvascular endothelial cells in vitro.

Journal: Microvascular research 20080401

Title: Blocking granule-mediated death by primary human NK cells requires both protection of mitochondria and inhibition of caspase activity.

Journal: Cell death and differentiation 20080401

Title: Nitric oxide and peroxynitrite signalling triggers homocysteine-mediated apoptosis in trigeminal sensory neurons in vitro.

Journal: Neuroscience research 20080401

Title: Combined treatment with L-carnitine and a pan-caspase inhibitor effectively reverses amiodarone-induced injury in cultured human lung epithelial cells.

Journal: Apoptosis : an international journal on programmed cell death 20080401

Title: Anti-fas activating antibody enhances trophoblast outgrowth on endometrial epithelial cells by induction of P38 MAPK/JNK-mediated apoptosis.

Journal: Placenta 20080401

Title: Acute-myeloid-leukemia-targeted toxins kill tumor cells by cell-type-specific mechanisms and synergize with TRAIL to allow manipulation of the extent and mechanism of tumor cell death.

Journal: Leukemia 20080301

Title: Cytoplasmic vacuolization responses to cytopathic bovine viral diarrhoea virus.

Journal: Virus research 20080301

Title: Transient protective effect of caspase inhibitors in RCS rat.

Journal: Experimental eye research 20080301

Title: Inhibition of caspase-8 activity reduces IFN-gamma expression by T cells from Leishmania major infection.

Journal: Anais da Academia Brasileira de Ciencias 20080301

Title: Denbinobin induces apoptosis in human lung adenocarcinoma cells via Akt inactivation, Bad activation, and mitochondrial dysfunction.

Journal: Toxicology letters 20080227

Title: Combinatorial-approached neuroprotection using pan-caspase inhibitor and poly (ADP-ribose) polymerase (PARP) inhibitor following experimental stroke in rats; is there additional benefit?

Journal: Brain research 20080221

Title: Treatment of PC-3 and DU145 prostate cancer cells by prenylflavonoids from hop (Humulus lupulus L.) induces a caspase-independent form of cell death.

Journal: Phytotherapy research : PTR 20080201

Title: Overexpression of Par-4 enhances thapsigargin-induced apoptosis via down-regulation of XIAP and inactivation of Akt in human renal cancer cells.

Journal: Journal of cellular biochemistry 20080201

Title: Resveratrol-induced apoptosis depends on the lipid kinase activity of Vps34 and on the formation of autophagolysosomes.

Journal: Carcinogenesis 20080201

Title: Inhibition of apoptosis facilitates necrosis induced by cisplatin in gastric cancer cells.

Journal: Anti-cancer drugs 20080201

Title: Cleavage of focal adhesion kinase is an early marker and modulator of oxidative stress-induced apoptosis.

Journal: Chemico-biological interactions 20080110

Title: Caspase inhibitor facilitates recovery of hearing by protecting the cochlear lateral wall from acute cochlear mitochondrial dysfunction.

Journal: Journal of neuroscience research 20080101

Title: Isoobtusilactone A induces both caspase-dependent and -independent apoptosis in Hep G2 cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080101

Title: Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells.

Journal: Cell death and differentiation 20080101

Title: Thiosulfinates from Allium tuberosum L. induce apoptosis via caspase-dependent and -independent pathways in PC-3 human prostate cancer cells.

Journal: Bioorganic & medicinal chemistry letters 20080101

Title: Caspase-independent cell death by CD300LF (MAIR-V), an inhibitory immunoglobulin-like receptor on myeloid cells.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20080101

Title: Apoptosis induction preceded by mitochondrial depolarization in multiple myeloma cell line U266 by 2-aminophenoxazine-3-one.

Journal: Biological & pharmaceutical bulletin 20080101

Title: Caspase assays: identifying caspase activity and substrates in vitro and in vivo.

Journal: Methods in enzymology 20080101

Title: Gross thymic extract, Thymax, induces apoptosis in human breast cancer cells in vitro through the mitochondrial pathway.

Journal: Anticancer research 20080101

Title: Cytotoxicity of mononuclear cells as induced by peritoneal dialysis fluids: insight into mechanisms that regulate osmotic stress-related apoptosis.

Journal: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20080101

Title: Apoptosis and autophagy as mechanisms of dinoflagellate symbiont release during cnidarian bleaching: every which way you lose.

Journal: Proceedings. Biological sciences 20071222

Title: Synthesis and evaluation of the antiproliferative activities of derivatives of carboxyalkyl isoflavones linked to N-t-Boc-hexylenediamine.

Journal: Journal of medicinal chemistry 20071213

Title: Three-dimensional cell organization leads to a different type of ionizing radiation-induced cell death: MG-63 monolayer cells undergo mitotic catastrophe while spheroids die of apoptosis.

Journal: International journal of oncology 20071201

Title: CTLA-4 . FasL induces early apoptosis of activated T cells by interfering with anti-apoptotic signals.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20071201

Title: Statins stimulate in vitro membrane FasL expression and lymphocyte apoptosis through RhoA/ROCK pathway in murine melanoma cells.

Journal: Neoplasia (New York, N.Y.) 20071201

Title: Synapse-specific plasticity in command neurons during learning of edible snails under the action of caspase inhibitors.

Journal: Bulletin of experimental biology and medicine 20071201

Title: Cdc42 regulates cofilin during the establishment of neuronal polarity.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20071128

Title: Hypoxia/reoxygenation induces apoptosis through a ROS-mediated caspase-8/Bid/Bax pathway in human lymphocytes.

Journal: Biochemical and biophysical research communications 20071123

Title: Improvement of the survival rate after rat massive hepatectomy due to the reduction of apoptosis by caspase inhibitor.

Journal: Journal of gastroenterology and hepatology 20071101

Title: Fibroblast apoptosis induced by Porphyromonas gingivalis is stimulated by a gingipain and caspase-independent pathway that involves apoptosis-inducing factor.

Journal: Cellular microbiology 20071101

Title: The VEGFR2 and PKA pathways converge at MEK/ERK1/2 to promote survival in serum deprived neuronal cells.

Journal: Molecular and cellular biochemistry 20071101

Title: Induction of autophagy in neurite degeneration of mouse superior cervical ganglion neurons.

Journal: The European journal of neuroscience 20071101

Title: 23,24-Dihydrocucurbitacin B induces G2/M cell-cycle arrest and mitochondria-dependent apoptosis in human breast cancer cells (Bcap37).

Journal: Cancer letters 20071028

Title: Caspase inhibitor Z-VAD-FMK enhances the freeze-thaw survival rate of human embryonic stem cells.

Journal: Bioscience reports 20071001

Title: Fluorescently labeled inhibitor for profiling cytoplasmic peptide:N-glycanase.

Journal: Glycobiology 20071001

Title: Cross-linking of CD54 on Burkitt lymphoma cell line Raji and Ramos induces FasL expression by reactive oxygen species and apoptosis of adjacent cells in Fas/FasL interaction.

Journal: Journal of immunotherapy (Hagerstown, Md. : 1997) 20071001

Title: Nuclear translocation of apoptosis inducing factor is associated with cisplatin induced apoptosis in LNCaP prostate cancer cells.

Journal: Cancer letters 20070918

Title: Revival of apoptotic cells that display early-stage dynamic membrane blebbing.

Journal: FEBS letters 20070918

Title: Neuronal death in the lateral geniculate nucleus of young ferrets following a cortical lesion: time-course, age dependence and involvement of caspases.

Journal: Brain research 20070905

Title: Influence of pan-caspase inhibitors on coxsackievirus B3-infected CD19+ B lymphocytes.

Journal: Apoptosis : an international journal on programmed cell death 20070901

Title: Perturbation of dopamine metabolism by 3-amino-2-(4'-halophenyl)propenes leads to increased oxidative stress and apoptotic SH-SY5Y cell death.

Journal: Molecular pharmacology 20070901

Title: Actinomycin D enhances TRAIL-induced caspase-dependent and -independent apoptosis in SH-SY5Y neuroblastoma cells.

Journal: Neuroscience research 20070901

Title: Calpain- and caspase-mediated alphaII-spectrin and tau proteolysis in rat cerebrocortical neuronal cultures after ecstasy or methamphetamine exposure.

Journal: The international journal of neuropsychopharmacology 20070801

Title: Apoptosis of human neutrophils induced by protein phosphatase 1/2A inhibition is caspase-independent and serine protease-dependent.

Journal: Journal of cellular physiology 20070801

Title: Effects of caspase inhibitors (z-VAD-fmk, z-VDVAD-fmk) on Nile Red fluorescence pattern in 7-ketocholesterol-treated cells: investigation by flow cytometry and spectral imaging microscopy.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20070801

Title: Labeling of apoptotic JURL-MK1 cells by fluorescent caspase-3 inhibitor FAM-DEVD-fmk occurs mainly at site(s) different from caspase-3 active site.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20070801

Title: Hsp72 controls bortezomib-induced HepG2 cell death via interaction with pro-apoptotic factors.

Journal: Oncology reports 20070801

Title: Effect of a novel fully human monovalent antigen-binding fragment on the survival of cancer cell lines.

Journal: Oncology reports 20070801

Title: Vitamins K2, K3 and K5 exert antitumor effects on established colorectal cancer in mice by inducing apoptotic death of tumor cells.

Journal: International journal of oncology 20070801

Title: Cytotoxicity of diacetoxyscirpenol is associated with apoptosis by activation of caspase-8 and interruption of cell cycle progression by down-regulation of cdk4 and cyclin B1 in human Jurkat T cells.

Journal: Toxicology and applied pharmacology 20070715

Title: Grifolin induces apoptosis via inhibition of PI3K/AKT signalling pathway in human osteosarcoma cells.

Journal: Apoptosis : an international journal on programmed cell death 20070701

Title: LAPSER1 is a putative cytokinetic tumor suppressor that shows the same centrosome and midbody subcellular localization pattern as p80 katanin.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070701

Title: Caspase 3 attenuates XIAP (X-linked inhibitor of apoptosis protein)-mediated inhibition of caspase 9.

Journal: The Biochemical journal 20070701

Title: P53-mediated cell cycle arrest and apoptosis through a caspase-3- independent, but caspase-9-dependent pathway in oridonin-treated MCF-7 human breast cancer cells.

Journal: Acta pharmacologica Sinica 20070701

Title: Antivasospastic and antiinflammatory effects of caspase inhibitor in experimental subarachnoid hemorrhage.

Journal: Journal of neurosurgery 20070701

Title: Olfactory ensheathing cell apoptosis induced by hypoxia and serum deprivation.

Journal: Neuroscience letters 20070629

Title: Antimycin A induces apoptosis in As4.1 juxtaglomerular cells.

Journal: Cancer letters 20070618

Title: Activation of an alternative death receptor-induced signaling pathway in human hepatocytes under caspase arrest.

Journal: Archives of biochemistry and biophysics 20070615

Title: Role of caspases in CD95L- and TRAIL-induced non-apoptotic signalling in pancreatic tumour cells.

Journal: Cellular signalling 20070601

Title: Cigarette smoke extract-induced suppression of caspase-3-like activity impairs human neutrophil phagocytosis.

Journal: American journal of physiology. Lung cellular and molecular physiology 20070601

Title: Hypoxia-induced apoptosis and tube breakdown are regulated by p38 MAPK but not by caspase cascade in an in vitro capillary model composed of human endothelial cells.

Journal: Journal of cellular physiology 20070601

Title: Targeting AML1/ETO-histone deacetylase repressor complex: a novel mechanism for valproic acid-mediated gene expression and cellular differentiation in AML1/ETO-positive acute myeloid leukemia cells.

Journal: The Journal of pharmacology and experimental therapeutics 20070601

Title: Caspase inhibition sensitizes inhibitor of NF-kappaB kinase beta-deficient fibroblasts to caspase-independent cell death via the generation of reactive oxygen species.

Journal: The Journal of biological chemistry 20070601

Title: (-)-Epigallocatechin gallate induces apoptosis, via caspase activation, in osteoclasts differentiated from RAW 264.7 cells.

Journal: Journal of periodontal research 20070601

Title: Monitoring of chemotherapy-induced cell death in melanoma tumors by N,N'-Didansyl-L-cystine.

Journal: Technology in cancer research & treatment 20070601

Title: [TAp63gamma-induced apoptosis mediated by apoptosis inducing factor in human esophageal squamous carcinoma EC9706 cells].

Journal: Zhonghua bing li xue za zhi = Chinese journal of pathology 20070601

Title: Apoptosis in sulfur mustard treated A549 cell cultures.

Journal: Life sciences 20070530

Title: Caspase inhibitor therapy enhances marginal mass islet graft survival and preserves long-term function in islet transplantation.

Journal: Diabetes 20070501

Title: Grape seed proanthocyanidins promote apoptosis in human epidermoid carcinoma A431 cells through alterations in Cdki-Cdk-cyclin cascade, and caspase-3 activation via loss of mitochondrial membrane potential.

Journal: Experimental dermatology 20070501

Title: Dual antiglioma action of metformin: cell cycle arrest and mitochondria-dependent apoptosis.

Journal: Cellular and molecular life sciences : CMLS 20070501

Title: Central injection of caspase inhibitors facilitates the formation of freezing behavior in rats.

Journal: Bulletin of experimental biology and medicine 20070501

Title: Ras-association domain family protein 6 induces apoptosis via both caspase-dependent and caspase-independent pathways.

Journal: Experimental cell research 20070415

Title: Hypoxia-induced cell death of HepG2 cells involves a necrotic cell death mediated by calpain.

Journal: Apoptosis : an international journal on programmed cell death 20070401

Title: Protective effect of caspase inhibitor on intestinal integrity in experimental severe acute pancreatitis.

Journal: The Journal of surgical research 20070401

Title: Agonists of TRAIL death receptors induce myeloma cell apoptosis that is not prevented by cells of the bone marrow microenvironment.

Journal: Leukemia 20070401

Title: Annexin-1 and peptide derivatives are released by apoptotic cells and stimulate phagocytosis of apoptotic neutrophils by macrophages.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20070401

Title: Autophagy is involved in cytotoxic effects of crotoxin in human breast cancer cell line MCF-7 cells.

Journal: Acta pharmacologica Sinica 20070401

Title: Quercetin-induced PC12 cell death accompanied by caspase-mediated DNA fragmentation.

Journal: Biological & pharmaceutical bulletin 20070401

Title: Pressure-dependent effect of shock waves on rat brain: induction of neuronal apoptosis mediated by a caspase-dependent pathway.

Journal: Journal of neurosurgery 20070401

Title: Canine coronavirus induces apoptosis in cultured cells.

Journal: Veterinary microbiology 20070331

Title: New thymidylate synthase inhibitors induce apoptosis in melanoma cell lines.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20070301

Title: Preventing chondrocyte programmed cell death caused by iatrogenic injury.

Journal: The Knee 20070301

Title: Mitochondria are not required for death receptor-mediated cytosolic acidification during apoptosis.

Journal: Apoptosis : an international journal on programmed cell death 20070301

Title: Remission-inducing effect of anti-TNF monoclonal antibody in TNBS colitis: mechanisms beyond neutralization?

Journal: Inflammatory bowel diseases 20070301

Title: Antiviral effects of pan-caspase inhibitors on the replication of coxsackievirus B3.

Journal: Apoptosis : an international journal on programmed cell death 20070301

Title: Caspase-11 regulates cell migration by promoting Aip1-Cofilin-mediated actin depolymerization.

Journal: Nature cell biology 20070301

Title: N-benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone reduces severity of experimental spinal cord injury.

Journal: Shock (Augusta, Ga.) 20070301

Title: Phenylalanine activates the mitochondria-mediated apoptosis through the RhoA/Rho-associated kinase pathway in cortical neurons.

Journal: The European journal of neuroscience 20070301

Title: Radiation-induced apoptosis in retinal progenitor cells is p53-dependent with caspase-independent DNA fragmentation.

Journal: The European journal of neuroscience 20070301

Title: Enhanced induction of mitochondrial damage and apoptosis in human leukemia HL-60 cells by the Ganoderma lucidum and Duchesnea chrysantha extracts.

Journal: Cancer letters 20070208

Title: Neurotoxic effects of homocysteine on cerebellar Purkinje neurons in vitro.

Journal: Neuroscience letters 20070208

Title: Broad-spectrum caspase inhibitors: from myth to reality?

Journal: Cell death and differentiation 20070201

Title: 20S-protopanaxadiol-induced programmed cell death in glioma cells through caspase-dependent and -independent pathways.

Journal: Journal of natural products 20070201

Title: Phenoxazine derivatives 2-amino-4,4alpha-dihydro-4alpha-phenoxazine-3-one and 2-aminophenoxazine-3-one-induced apoptosis through a caspase-independent mechanism in human neuroblastoma cell line NB-1 cells.

Journal: Biological & pharmaceutical bulletin 20070201

Title: Checkpoint kinase 1 is cleaved in a caspase-dependent pathway during genotoxic stress-induced apoptosis.

Journal: Biological & pharmaceutical bulletin 20070201

Title: Docetaxel-induced apoptosis in melanoma cells is dependent on activation of caspase-2.

Journal: Molecular cancer therapeutics 20070201

Title: [Effect of lidamycin on mitochondria initiated apoptotic pathway in human cancer cells].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20070201

Title: The concentration-dependent chemokine release and pro-apoptotic effects of neutrophil-derived alpha-defensin-1 on human bronchial and alveolar epithelial cells.

Journal: Life sciences 20070130

Title: Gossypol induces apoptosis in human PC-3 prostate cancer cells by modulating caspase-dependent and caspase-independent cell death pathways.

Journal: Life sciences 20070130

Title: Caspase-dependent and -independent induction of phosphatidylserine externalization during apoptosis in human renal carcinoma Cak(1)-1 and A-498 cells.

Journal: Toxicology 20070105

Title: Chondrocyte apoptosis is not essential for cartilage calcification: evidence from an in vitro avian model.

Journal: Journal of cellular biochemistry 20070101

Title: Adenoviral expression of XIAP antisense RNA induces apoptosis in glioma cells and suppresses the growth of xenografts in nude mice.

Journal: Gene therapy 20070101

Title: Cytolytic cells induce HMGB1 release from melanoma cell lines.

Journal: Journal of leukocyte biology 20070101

Title: IgA Fc receptor I signals apoptosis through the FcRgamma ITAM and affects tumor growth.

Journal: Blood 20070101

Title: Etodolac, a selective cyclooxygenase-2 inhibitor, induces apoptosis by activating caspases in human malignant rhabdoid tumor cells (FRTK-1).

Journal: Oncology reports 20070101

Title: Phenoxazine derivatives induce caspase-independent cell death in human glioblastoma cell lines, A-172 and U-251 MG.

Journal: Oncology reports 20070101

Title: Mitochondria-dependent apoptosis induced by nanoscale hydroxyapatite in human gastric cancer SGC-7901 cells.

Journal: Biological & pharmaceutical bulletin 20070101

Title: Targeted induction of apoptosis via TRAIL and cryoablation: a novel strategy for the treatment of prostate cancer.

Journal: Prostate cancer and prostatic diseases 20070101

Title: Induction of apoptosis by iridovirus virion protein extract.

Journal: Archives of virology 20070101

Title: ROS mediates baicalin-induced apoptosis in human promyelocytic leukemia HL-60 cells through the expression of the Gadd153 and mitochondrial-dependent pathway.

Journal: Anticancer research 20070101

Title: A calpain-like protease inhibits autophagic cell death.

Journal: Autophagy 20070101

Title: Effect of caspase inhibition on thymic apoptosis in hemorrhagic shock.

Journal: Journal of investigative surgery : the official journal of the Academy of Surgical Research 20070101

Title: Apoptosis and autophagy in photoreceptors exposed to oxidative stress.

Journal: Autophagy 20070101

Title: Berberine induces apoptosis in human HSC-3 oral cancer cells via simultaneous activation of the death receptor-mediated and mitochondrial pathway.

Journal: Anticancer research 20070101

Title: zVAD-fmk, unlike BocD-fmk, does not inhibit caspase-6 acting on 14-3-3/Bad pathway in apoptosis of p815 mastocytoma cells.

Journal: Experimental & molecular medicine 20061231

Title: Caspase independence of radio-induced cell death.

Journal: Oncogene 20061214

Title: Imatinib mesylate (Gleevec) enhances mature osteoclast apoptosis and suppresses osteoclast bone resorbing activity.

Journal: European journal of pharmacology 20061203

Title: Neurotoxicity of oxaliplatin and cisplatin for dorsal root ganglion neurons correlates with platinum-DNA binding.

Journal: Neurotoxicology 20061201

Title: The extracellular release of HMGB1 during apoptotic cell death.

Journal: American journal of physiology. Cell physiology 20061201

Title: Activation of caspase-8 and caspase-12 pathways by 7-ketocholesterol in human retinal pigment epithelial cells.

Journal: Investigative ophthalmology & visual science 20061201

Title: Magnolol-induced apoptosis is mediated via the intrinsic pathway with release of AIF from mitochondria in U937 cells.

Journal: Biological & pharmaceutical bulletin 20061201

Title: Buthionine sulfoximine enhancement of arsenic trioxide-induced apoptosis in leukemia and lymphoma cells is mediated via activation of c-Jun NH2-terminal kinase and up-regulation of death receptors.

Journal: Cancer research 20061201

Title: Topoisomerase II and tubulin inhibitors both induce the formation of apoptotic topoisomerase I cleavage complexes.

Journal: Molecular cancer therapeutics 20061201

Title: Proteasome inhibition induces both pro- and anti-cell death pathways in prostate cancer cells.

Journal: Cancer letters 20061118

Title: Hypoxia-induced cytoskeleton disruption in alveolar epithelial cells.

Journal: American journal of respiratory cell and molecular biology 20061101

Title: Improved survival of vitrified porcine embryos after partial delipation through chemically stimulated lipolysis and inhibition of apoptosis.

Journal: Theriogenology 20061101

Title: Glioblastoma cell death induced by asiatic acid.

Journal: Cell biology and toxicology 20061101

Title: Cytokine cooperation in renal tubular cell injury: the role of TWEAK.

Journal: Kidney international 20061101

Title: Involvement of both caspase-dependent and -independent pathways in apoptotic induction by hexaminolevulinate-mediated photodynamic therapy in human lymphoma cells.

Journal: Apoptosis : an international journal on programmed cell death 20061101

Title: Yersinia YopP-induced apoptotic cell death in murine dendritic cells is partially independent from action of caspases and exhibits necrosis-like features.

Journal: Apoptosis : an international journal on programmed cell death 20061101

Title: Bortezomib induces different apoptotic rates in B-CLL cells according to IgVH and BCL-6 mutations.

Journal: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20061101

Title: Mechanisms of cell death of neural progenitor cells caused by trophic support deprivation.

Journal: European journal of pharmacology 20061024

Title: Caspase inhibitors promote alternative cell death pathways.

Journal: Science's STKE : signal transduction knowledge environment 20061024

Title: Molecular events contributing to cell death in malignant human hematopoietic cells elicited by an IgG3-avidin fusion protein targeting the transferrin receptor.

Journal: Blood 20061015

Title: Berberine inhibits growth, induces G1 arrest and apoptosis in human epidermoid carcinoma A431 cells by regulating Cdki-Cdk-cyclin cascade, disruption of mitochondrial membrane potential and cleavage of caspase 3 and PARP.

Journal: Carcinogenesis 20061001

Title: Activation of dual apoptotic pathways in human melanocytes and protection by survivin.

Journal: The Journal of investigative dermatology 20061001

Title: Green tea polyphenols-induced apoptosis in human osteosarcoma SAOS-2 cells involves a caspase-dependent mechanism with downregulation of nuclear factor-kappaB.

Journal: Toxicology and applied pharmacology 20061001

Title: Trimethyltin-induced apoptosis is associated with upregulation of inducible nitric oxide synthase and Bax in a hippocampal cell line.

Journal: Toxicology and applied pharmacology 20061001

Title: Efflux of potassium ion is an important reason of HL-60 cells apoptosis induced by tachyplesin.

Journal: Acta pharmacologica Sinica 20061001

Title: Caspase-dependent cell death involved in brain damage after acute subdural hematoma in rats.

Journal: Brain research 20060921

Title: Expression and characterization of constitutively active human caspase-14.

Journal: Biochemical and biophysical research communications 20060908

Title: Pharmacological induction of Hsp70 protects apoptosis-prone cells from doxorubicin: comparison with caspase-inhibitor- and cycle-arrest-mediated cytoprotection.

Journal: Cell death and differentiation 20060901

Title: Proteolytic cleavage of Livin (ML-IAP) in apoptotic melanoma cells potentially mediated by a non-canonical caspase.

Journal: Journal of dermatological science 20060901

Title: Caspase cascade of Fas-mediated apoptosis in human normal endometrium and endometrial carcinoma cells.

Journal: Molecular human reproduction 20060901

Title: Tauroursodeoxycholic acid modulates p53-mediated apoptosis in Alzheimer's disease mutant neuroblastoma cells.

Journal: Journal of neurochemistry 20060901

Title: Glutamate-induced protease-mediated loss of plasma membrane Ca2+ pump activity in rat hippocampal neurons.

Journal: Journal of neurochemistry 20060901

Title: Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis.

Journal: Nature medicine 20060901

Title: Caspase-dependent and caspase-independent apoptosis induced by evodiamine in human leukemic U937 cells.

Journal: Molecular cancer therapeutics 20060901

Title: Induction of apoptosis in K562/ADM cells by gamma-linolenic acid involves lipid peroxidation and activation of caspase-3.

Journal: Chemico-biological interactions 20060825

Title: Induction of apoptosis by Meretrix lusoria through reactive oxygen species production, glutathione depletion, and caspase activation in human leukemia cells.

Journal: Life sciences 20060815

Title: Serofendic acid, a neuroprotective substance derived from fetal calf serum, inhibits mitochondrial membrane depolarization and caspase-3 activation.

Journal: European journal of pharmacology 20060807

Title: Phellinus linteus sensitises apoptosis induced by doxorubicin in prostate cancer.

Journal: British journal of cancer 20060807

Title: Apoptosis-inducing active components from Corbicula fluminea through activation of caspase-2 and production of reactive oxygen species in human leukemia HL-60 cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060801

Title: Effect of drug-induced cytotoxicity on glucose uptake in Hodgkin's lymphoma cells.

Journal: European journal of haematology 20060801

Title: Apoptotic effect of ethyl-4-isothiocyanatobutanoate is associated with DNA damage, proteasomal activity and induction of p53 and p21cip1/waf1.

Journal: Apoptosis : an international journal on programmed cell death 20060801

Title: Inhibition of cellular respiration by doxorubicin.

Journal: Chemical research in toxicology 20060801

Title: Gliotoxin induces caspase-dependent neurite degeneration and calpain-mediated general cytotoxicity in differentiated human neuroblastoma SH-SY5Y cells.

Journal: Biochemical and biophysical research communications 20060707

Title: The course of etoposide-induced apoptosis in Jurkat cells lacking p53 and Bax.

Journal: Journal of cellular physiology 20060701

Title: Cytosolic acidification and lysosomal alkalinization during TNF-alpha induced apoptosis in U937 cells.

Journal: Apoptosis : an international journal on programmed cell death 20060701

Title: Novel titanocene anti-cancer drugs and their effect on apoptosis and the apoptotic pathway in prostate cancer cells.

Journal: Apoptosis : an international journal on programmed cell death 20060701

Title: Differential protective effects of palmitoleic acid and cAMP on caspase activation and cell viability in pancreatic beta-cells exposed to palmitate.

Journal: Apoptosis : an international journal on programmed cell death 20060701

Title: Peri-nuclear clustering of mitochondria is triggered during aluminum maltolate induced apoptosis.

Journal: Journal of Alzheimer's disease : JAD 20060701

Title: Enzastaurin (LY317615), a protein kinase Cbeta inhibitor, inhibits the AKT pathway and induces apoptosis in multiple myeloma cell lines.

Journal: Molecular cancer therapeutics 20060701

Title: 15-Deoxy-Delta12,14-prostaglandin J(2) induces death receptor 5 expression through mRNA stabilization independently of PPARgamma and potentiates TRAIL-induced apoptosis.

Journal: Molecular cancer therapeutics 20060701

Title: Stat3 cleavage by caspases: impact on full-length Stat3 expression, fragment formation, and transcriptional activity.

Journal: The Journal of biological chemistry 20060630

Title: Hydrogen peroxide-mediated necrosis induction in HUVECs is associated with an atypical pattern of caspase-3 cleavage.

Journal: Experimental cell research 20060610

Title: Xaf1 can cooperate with TNFalpha in the induction of apoptosis, independently of interaction with XIAP.

Journal: Molecular and cellular biochemistry 20060601

Title: Beneficial effects of intra-articular caspase inhibition therapy following osteochondral injury.

Journal: Osteoarthritis and cartilage 20060601

Title: Caspase activation contributes to endotoxin-induced diaphragm weakness.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20060601

Title: Macrophages but not smooth muscle cells undergo benzyloxycarbonyl-Val-Ala-DL-Asp(O-Methyl)-fluoromethylketone-induced nonapoptotic cell death depending on receptor-interacting protein 1 expression: implications for the stabilization of macrophage-rich atherosclerotic plaques.

Journal: The Journal of pharmacology and experimental therapeutics 20060601

Title: Proteasome inhibition by MG-132 induces apoptotic cell death and mitochondrial dysfunction in cultured rat brain oligodendrocytes but not in astrocytes.

Journal: Glia 20060601

Title: G3139 induces cell death by caspase-dependent and -independent apoptosis on human melanoma cell lines.

Journal: Oncology reports 20060601

Title: N-benzyladriamycin-14-valerate (AD 198) activates protein kinase C-delta holoenzyme to trigger mitochondrial depolarization and cytochrome c release independently of permeability transition pore opening and Ca2+ influx.

Journal: Anti-cancer drugs 20060601

Title: The neurotoxic effects of amitriptyline are mediated by apoptosis and are effectively blocked by inhibition of caspase activity.

Journal: Anesthesia and analgesia 20060601

Title: Inhibition of apoptosis in early tooth development alters tooth shape and size.

Journal: Journal of dental research 20060601

Title: Caspase inhibitors reduce severity of cartilage lesions in experimental osteoarthritis.

Journal: Arthritis and rheumatism 20060601

Title: Interleukin-6 protects annulus fibrosus cell from apoptosis induced by interleukin-1 beta in vitro.

Journal: Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20060601

Title: Inhibition of calpain and caspase-3 prevented apoptosis and preserved electrophysiological properties of voltage-gated and ligand-gated ion channels in rat primary cortical neurons exposed to glutamate.

Journal: Neuroscience 20060512

Title: Local thymic caspase-9 inhibition improves survival during polymicrobial sepsis in mice.

Journal: Journal of molecular medicine (Berlin, Germany) 20060501

Title: Statin-induced proinflammatory response in mitogen-activated peripheral blood mononuclear cells through the activation of caspase-1 and IL-18 secretion in monocytes.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20060501

Title: Proteolytic regulation of nuclear factor of activated T (NFAT) c2 cells and NFAT activity by caspase-3.

Journal: The Journal of biological chemistry 20060421

Title: Caspase inhibition in apoptotic T cells triggers necrotic cell death depending on the cell type and the proapoptotic stimulus.

Journal: Journal of cellular biochemistry 20060415

Title: Apoptin-induced cell death is modulated by Bcl-2 family members and is Apaf-1 dependent.

Journal: Oncogene 20060406

Title: Functional dissociation of DeltaPsim and cytochrome c release defines the contribution of mitochondria upstream of caspase activation during granzyme B-induced apoptosis.

Journal: Cell death and differentiation 20060401

Title: Effect of staurosporine-induced apoptosis on endothelial nitric oxide synthase in transfected COS-7 cells and primary endothelial cells.

Journal: Cell death and differentiation 20060401

Title: Thymidine-phosphorothioate oligonucleotides induce activation and apoptosis of CLL cells independently of CpG motifs or BCL-2 gene interference.

Journal: Leukemia 20060401

Title: In vitro anti-cancer activity of a novel microbial fermentation product on human carcinomas.

Journal: International journal of molecular medicine 20060401

Title: Contributions of autophagic and apoptotic mechanisms to CrTX-induced death of K562 cells.

Journal: Toxicon : official journal of the International Society on Toxinology 20060401

Title: Role of caspases on cell death, inflammation, and cell cycle in glycerol-induced acute renal failure.

Journal: Kidney international 20060401

Title: Nucleofection, an efficient nonviral method to transfer genes into human hematopoietic stem and progenitor cells.

Journal: Stem cells and development 20060401

Title: AMP-activated protein kinase protects against anti-epidermal growth factor receptor-Pseudomonas exotoxin A immunotoxin-induced MA11 breast cancer cell death.

Journal: Molecular cancer therapeutics 20060401

Title: Design, synthesis, and biological evaluation of isoquinoline-1,3,4-trione derivatives as potent caspase-3 inhibitors.

Journal: Journal of medicinal chemistry 20060309

Title: Role of caspases in acetaminophen-induced liver injury.

Journal: Life sciences 20060306

Title: Necrosis is associated with IL-6 production but apoptosis is not.

Journal: Cellular signalling 20060301

Title: The role of CAP3 in CD95 signaling: new insights into the mechanism of procaspase-8 activation.

Journal: Cell death and differentiation 20060301

Title: Cell surface expression of intermediate filament proteins vimentin and lamin B1 in human neutrophil spontaneous apoptosis.

Journal: Journal of leukocyte biology 20060301

Title: Endoplasmic reticulum Ca2+ depletion induces endothelial cell apoptosis independently of caspase-12.

Journal: Cardiovascular research 20060301

Title: Decreased expression of pro-apoptotic Bcl-2 family members during retinal development and differential sensitivity to cell death.

Journal: Developmental biology 20060301

Title: Mechanisms of cardiotoxin lll-induced apoptosis in human colorectal cancer colo205 cells.

Journal: Clinical and experimental pharmacology & physiology 20060301

Title: Inhibition of the phosphatidylinositol 3-kinase/Akt pathway sensitizes MDA-MB468 human breast cancer cells to cerulenin-induced apoptosis.

Journal: Molecular cancer therapeutics 20060301

Title: The BTB-kelch protein LZTR-1 is a novel Golgi protein that is degraded upon induction of apoptosis.

Journal: The Journal of biological chemistry 20060224

Title: Apoptosis induction by dohevanil, a DHA substitutive analog of capsaicin, in MCF-7 cells.

Journal: Life sciences 20060223

Title: The human transcription factor AP-1 is a mediator of bile acid-induced liver cell apoptosis.

Journal: Biochemical and biophysical research communications 20060217

Title: Involvement of the ubiquitin pathway in decreasing Ku70 levels in response to drug-induced apoptosis.

Journal: Experimental cell research 20060215

Title: Histone deacetylase inhibitors require caspase activity to induce apoptosis in lung and prostate carcinoma cells.

Journal: Cancer letters 20060208

Title: Inhibition of lung cancer cell growth by quercetin glucuronides via G2/M arrest and induction of apoptosis.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060201

Title: Differential caspase-9-dependent signaling pathway between tumor necrosis factor receptor- and Fas-mediated hepatocyte apoptosis in mice.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20060201

Title: Peptide vaccination of mice immune to LCMV or vaccinia virus causes serious CD8 T cell-mediated, TNF-dependent immunopathology.

Journal: The Journal of clinical investigation 20060201

Title: Evaluation of the reactivity of apoptosis markers before and after cryopreservation in cord blood CD34(+) cells.

Journal: Stem cells and development 20060201

Title: G-protein-coupled OX1 orexin/hcrtr-1 hypocretin receptors induce caspase-dependent and -independent cell death through p38 mitogen-/stress-activated protein kinase.

Journal: The Journal of biological chemistry 20060113

Title: z-VAD-fmk inhibits peptide:N-glycanase and may result in ER stress.

Journal: Cell death and differentiation 20060101

Title: Synergistic protection of a general caspase inhibitor and MK-801 in bilirubin-induced cell death in human NT2-N neurons.

Journal: Pediatric research 20060101

Title: E. coli infection induces caspase dependent degradation of NF-kappaB and reduces the inflammatory response in macrophages.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20060101

Title: Caspase activation and apoptosis induction by adalimumab: demonstration in vitro and in vivo in a chimeric mouse model.

Journal: Inflammatory bowel diseases 20060101

Title: Nuclear caspase-3 and caspase-7 activation, and poly(ADP-ribose) polymerase cleavage are early events in camptothecin-induced apoptosis.

Journal: Apoptosis : an international journal on programmed cell death 20060101

Title: Inhibition of UVA-induced c-Jun N-terminal kinase activity results in caspase-dependent apoptosis in human keratinocytes.

Journal: Photochemistry and photobiology 20060101

Title: Enhanced cellular respiration in cells exposed to doxorubicin.

Journal: Molecular pharmaceutics 20060101

Title: Camptothecin induces the transit of FasL trimers to the cell surface in apoptotic HEp-2 cells.

Journal: Cellular & molecular biology letters 20060101

Title: z-VAD-fmk-induced non-apoptotic cell death of macrophages: possibilities and limitations for atherosclerotic plaque stabilization.

Journal: Autophagy 20060101

Title: The atypical pattern of cell death in B16F10 melanoma cells treated with TNP-470.

Journal: Cellular & molecular biology letters 20060101

Title: Porcine islet graft function is affected by pretreatment with a caspase-3 inhibitor.

Journal: Cell transplantation 20060101

Title: Congener-specific polychlorinated biphenyl-induced cell death in human kidney cells in vitro: potential role of caspase.

Journal: International journal of toxicology 20060101

Title: Apoptosis and redistribution of the Ro autoantigen in Balb/c mouse like in subacute cutaneous lupus erythematosus.

Journal: Clinical & developmental immunology 20060101

Title: Molecular mechanism of matrine-induced apoptosis in leukemia K562 cells.

Journal: The American journal of Chinese medicine 20060101

Title: Apoptosis inhibition in T cells triggers the expression of proinflammatory cytokines--implications for the CNS.

Journal: Journal of neural transmission. Supplementum 20060101

Title: Cutting edge: FADD is not required for antigen receptor-mediated NF-kappaB activation.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20051215

Title: Disruption of renal peritubular blood flow in lipopolysaccharide-induced renal failure: role of nitric oxide and caspases.

Journal: American journal of physiology. Renal physiology 20051201

Title: Phosphatidylserine externalization in human sperm induced by calcium ionophore A23187: relationship with apoptosis, membrane scrambling and the acrosome reaction.

Journal: Human reproduction (Oxford, England) 20051201

Title: Role of mitochondria in tamoxifen-induced rapid death of MCF-7 breast cancer cells.

Journal: Apoptosis : an international journal on programmed cell death 20051201

Title: Contribution of reactive oxygen species and caspase-3 to apoptosis and attenuated ICAM-1 expression by paclitaxel-treated MDA-MB-435 breast carcinoma cells.

Journal: International journal of oncology 20051201

Title: The augmentation of TNFalpha-induced cell death in murine L929 fibrosarcoma by the pan-caspase inhibitor Z-VAD-fmk through pre-mitochondrial and MAPK-dependent pathways.

Journal: Acta medica Okayama 20051201

Title: Fluorescence based oxygen uptake analysis in the study of metabolic responses to apoptosis induction.

Journal: Journal of immunological methods 20051130

Title: Induction of apoptosis in macrophages by air oxidation of dioleoylphosphatidylglycerol.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20051128

Title: Caspase-3 is required in the apoptotic disintegration of the nuclear matrix.

Journal: Experimental cell research 20051115

Title: Sensitization for gamma-irradiation-induced apoptosis by second mitochondria-derived activator of caspase.

Journal: Cancer research 20051115

Title: Caspase 8/10 are not mediating apoptosis in neuroblastoma cells treated with CDK inhibitory drugs.

Journal: European journal of pharmacology 20051107

Title: Compounds blocking mutant huntingtin toxicity identified using a Huntington's disease neuronal cell model.

Journal: Neurobiology of disease 20051101

Title: Apoptosis of bovine ovarian surface epithelial cells by Fas antigen/Fas ligand signaling.

Journal: Reproduction (Cambridge, England) 20051101

Title: Neuroprotective effect of zVAD against the neurotoxin 3-nitropropionic acid involves inhibition of calpain.

Journal: Neuropharmacology 20051001

Title: Cell death pathways in juvenile Batten disease.

Journal: Apoptosis : an international journal on programmed cell death 20051001

Title: Caspase-independent death of Leber's hereditary optic neuropathy cybrids is driven by energetic failure and mediated by AIF and Endonuclease G.

Journal: Apoptosis : an international journal on programmed cell death 20051001

Title: Upregulation of alpha globin promotes apoptotic cell death in the hematopoietic cell line FL5.12.

Journal: Apoptosis : an international journal on programmed cell death 20051001

Title: Motexafin gadolinium induces mitochondrially-mediated caspase-dependent apoptosis.

Journal: Apoptosis : an international journal on programmed cell death 20051001

Title: Induction of apoptosis by spermine-metabolites in primary human blood cells and various tumor cell lines.

Journal: Apoptosis : an international journal on programmed cell death 20051001

Title: Irreversible pan-ErbB tyrosine kinase inhibitor CI-1033 induces caspase-independent apoptosis in colorectal cancer DiFi cell line.

Journal: Apoptosis : an international journal on programmed cell death 20051001

Title: Inhibition of N-methyl-D-aspartate receptors increases paraoxon-induced apoptosis in cultured neurons.

Journal: Toxicology and applied pharmacology 20051001

Title: Apoptosis induced by N6-substituted derivatives of adenosine is related to intracellular accumulation of corresponding mononucleotides in HL-60 cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20051001

Title: Involvement of poly(ADP-ribose) polymerase activity in regulating Chk1-dependent apoptotic cell death.

Journal: DNA repair 20050928

Title: In vitro properties of 5-(benzylsulfonyl)-4-bromo-2-methyl-3(2H)-pyridazinone: a novel permeability transition pore inhibitor.

Journal: European journal of pharmacology 20050905

Title: p53-dependent caspase-2 activation in mitochondrial release of apoptosis-inducing factor and its role in renal tubular epithelial cell injury.

Journal: The Journal of biological chemistry 20050902

Title: Apoptosis of ejaculated human sperm is induced by co-incubation with Chlamydia trachomatis lipopolysaccharide.

Journal: Human reproduction (Oxford, England) 20050901

Title: Paclitaxel induces apoptosis via caspase-3 activation in human osteogenic sarcoma cells (U-2 OS).

Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20050901

Title: Tumor necrosis factor-related apoptosis-inducing ligand-mediated proliferation of tumor cells with receptor-proximal apoptosis defects.

Journal: Cancer research 20050901

Title: Depletion of the AP-1 repressor JDP2 induces cell death similar to apoptosis.

Journal: Biochimica et biophysica acta 20050815

Title: Nonoxynol-9 induces apoptosis of endometrial explants by both caspase-dependent and -independent apoptotic pathways.

Journal: Biology of reproduction 20050801

Title: Antitumor activity of cationic liposome-mediated Bax gene transfer in osteosarcoma cells: induction of apoptosis and caspase-independent cell death.

Journal: International journal of oncology 20050801

Title: Glycyrrhizin induces apoptosis in human stomach cancer KATO III and human promyelotic leukemia HL-60 cells.

Journal: International journal of molecular medicine 20050801

Title: Sendai virus trailer RNA simultaneously blocks two apoptosis-inducing mechanisms in a cell type-dependent manner.

Journal: The Journal of general virology 20050801

Title: Gap junction blockage limits intercellular spreading of astrocytic apoptosis induced by metabolic depression.

Journal: Journal of neurochemistry 20050801

Title: Pristimerin induces caspase-dependent apoptosis in MDA-MB-231 cells via direct effects on mitochondria.

Journal: Molecular cancer therapeutics 20050801

Title: Caspase-dependent and -independent activation of acid sphingomyelinase signaling.

Journal: The Journal of biological chemistry 20050715

Title: Membrane type 1-matrix metalloproteinase induces endothelial cell morphogenic differentiation by a caspase-dependent mechanism.

Journal: Experimental cell research 20050715

Title: Regulatory roles of cell surface sialylation in susceptibility to sphingomyelinase in human diffuse large B cell lymphoma.

Journal: International journal of oncology 20050701

Title: Phosphatase-1 and -2A inhibition modulates apoptosis in human osteoarthritis chondrocytes independently of nitric oxide production.

Journal: Annals of the rheumatic diseases 20050701

Title: Induction of caspase-3-dependent apoptosis in human leukemia HL-60 cells by paclitaxel.

Journal: Clinica chimica acta; international journal of clinical chemistry 20050701

Title: Involvement of lysosomal cathepsins in the cleavage of DNA topoisomerase I during necrotic cell death.

Journal: Arthritis and rheumatism 20050701

Title: Interactive effects of HDAC inhibitors and TRAIL on apoptosis are associated with changes in mitochondrial functions and expressions of cell cycle regulatory genes in multiple myeloma.

Journal: Neoplasia (New York, N.Y.) 20050701

Title: Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury.

Journal: Nature chemical biology 20050701

Title: Reversibility of caspase activation and its role during glycochenodeoxycholate-induced hepatocyte apoptosis.

Journal: The Journal of biological chemistry 20050624

Title: Caspase-independent cell death by allicin in human epithelial carcinoma cells: involvement of PKA.

Journal: Cancer letters 20050616

Title: Actinonin induces apoptosis in U937 leukemia cells.

Journal: Cancer letters 20050608

Title: The unfolded protein response modulates toxicity of the expanded glutamine androgen receptor.

Journal: The Journal of biological chemistry 20050603

Title: Glutaric acid and its metabolites cause apoptosis in immature oligodendrocytes: a novel mechanism of white matter degeneration in glutaryl-CoA dehydrogenase deficiency.

Journal: Pediatric research 20050601

Title: Up-regulation of tissue factor activity on human proximal tubular epithelial cells in response to Shiga toxin.

Journal: Kidney international 20050601

Title: Programmed cell death in Blastocystis hominis occurs independently of caspase and mitochondrial pathways.

Journal: Biochimie 20050601

Title: Effect of caspase inhibitors on the post-thaw motility, and integrity of acrosome and plasma membrane of cryopreserved equine spermatozoa.

Journal: Indian journal of experimental biology 20050601

Title: N-benzoylstaurosporine (PKC412) inhibits Akt kinase inducing apoptosis in multiple myeloma cells.

Journal: Leukemia & lymphoma 20050601

Title: Induction of reactive oxygen intermediates-dependent programmed cell death in human malignant ex vivo glioma cells and inhibition of the vascular endothelial growth factor production by taurolidine.

Journal: Journal of neurosurgery 20050601

Title: Essential roles of Atg5 and FADD in autophagic cell death: dissection of autophagic cell death into vacuole formation and cell death.

Journal: The Journal of biological chemistry 20050527

Title: Early apoptotic and late necrotic components associated with altered Ca2+ homeostasis in a peptide-delivery model of polyglutamine-induced neuronal death.

Journal: Journal of neuroscience research 20050515

Title: Preferential cell death of CD8+ effector memory (CCR7-CD45RA-) T cells by hydrogen peroxide-induced oxidative stress.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20050515

Title: Apigenin drives the production of reactive oxygen species and initiates a mitochondrial mediated cell death pathway in prostate epithelial cells.

Journal: The Prostate 20050501

Title: Generation and functional significance of CXC chemokines for neutrophil-induced liver injury during endotoxemia.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20050501

Title: Death receptor-mediated apoptosis in human malignant glioma cells: modulation by the CD40/CD40L system.

Journal: Journal of neuroimmunology 20050501

Title: Flavone initiates a hierarchical activation of the caspase-cascade in colon cancer cells.

Journal: Apoptosis : an international journal on programmed cell death 20050501

Title: A novel targeted therapy of Leydig and granulosa cell tumors through the luteinizing hormone receptor using a hecate-chorionic gonadotropin beta conjugate in transgenic mice.

Journal: Neoplasia (New York, N.Y.) 20050501

Title: Effect of ZVAD-fmk on hepatocyte apoptosis after bile duct ligation in rat.

Journal: World journal of gastroenterology 20050421

Title: Two Arabidopsis metacaspases AtMCP1b and AtMCP2b are arginine/lysine-specific cysteine proteases and activate apoptosis-like cell death in yeast.

Journal: The Journal of biological chemistry 20050415

Title: Toxicity and detoxification of lipid-derived aldehydes in cultured retinal pigmented epithelial cells.

Journal: Toxicology and applied pharmacology 20050415

Title: Sensitization of stefin B-deficient thymocytes towards staurosporin-induced apoptosis is independent of cysteine cathepsins.

Journal: FEBS letters 20050411

Title: Hsp27 and Hsp70 administered in combination have a potent protective effect against FALS-associated SOD1-mutant-induced cell death in mammalian neuronal cells.

Journal: Brain research. Molecular brain research 20050404

Title: z-VAD-fmk augmentation of TNF alpha-stimulated neutrophil apoptosis is compound specific and does not involve the generation of reactive oxygen species.

Journal: Blood 20050401

Title: Caspase-dependent apoptosis induction by phenethyl isothiocyanate, a cruciferous vegetable-derived cancer chemopreventive agent, is mediated by Bak and Bax.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050401

Title: Resveratrol-induced apoptotic death in human U251 glioma cells.

Journal: Molecular cancer therapeutics 20050401

Title: Mechanism of cell death induced by cationic dendrimers in RAW 264.7 murine macrophage-like cells.

Journal: The Journal of pharmacy and pharmacology 20050401

Title: Cytotoxicity characterization of catanionic vesicles in RAW 264.7 murine macrophage-like cells.

Journal: Colloids and surfaces. B, Biointerfaces 20050325

Title: A role for caspases in controlling IL-4 expression in T cells.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20050315

Title: Hsp72 inhibits Fas-mediated apoptosis upstream of the mitochondria in type II cells.

Journal: The Journal of biological chemistry 20050311

Title: Apoptosis of airway epithelial cells in response to meconium.

Journal: Life sciences 20050304

Title: Requirement for caspase-8 in NF-kappaB activation by antigen receptor.

Journal: Science (New York, N.Y.) 20050304

Title: Pathways of caspase-mediated apoptosis in autosomal-dominant polycystic kidney disease (ADPKD).

Journal: Kidney international 20050301

Title: Role of the autophagic-lysosomal system on low potassium-induced apoptosis in cultured cerebellar granule cells.

Journal: Journal of neurochemistry 20050301

Title: Boswellic acid acetate induces apoptosis through caspase-mediated pathways in myeloid leukemia cells.

Journal: Molecular cancer therapeutics 20050301

Title: Intrinsic pathway of hydroquinone induced apoptosis occurs via both caspase-dependent and caspase-independent mechanisms.

Journal: Chemical research in toxicology 20050301

Title: Smac/DIABLO and cytochrome c are released from mitochondria through a similar mechanism during UV-induced apoptosis.

Journal: Apoptosis : an international journal on programmed cell death 20050301

Title: Inhibition of caspases alleviates gentamicin-induced cochlear damage in guinea pigs.

Journal: Auris, nasus, larynx 20050301

Title: Pomolic acid triggers mitochondria-dependent apoptotic cell death in leukemia cell line.

Journal: Cancer letters 20050227

Title: Exposure to hypoxia rapidly induces mitochondrial channel activity within a living synapse.

Journal: The Journal of biological chemistry 20050211

Title: Caprine herpesvirus-1 (CapHV-1) induces apoptosis in goat peripheral blood mononuclear cells.

Journal: Veterinary immunology and immunopathology 20050210

Title: Acacetin induces apoptosis in human gastric carcinoma cells accompanied by activation of caspase cascades and production of reactive oxygen species.

Journal: Journal of agricultural and food chemistry 20050209

Title: Mitochondria from TRAIL-resistant prostate cancer cells are capable of responding to apoptotic stimuli.

Journal: Cellular signalling 20050201

Title: Protein kinase C delta is not activated by caspase-3 and its inhibition is sufficient to induce apoptosis in the colon cancer line, COLO 205.

Journal: Cellular signalling 20050201

Title: Failure of caspase inhibition in the double-lesion rat model of striatonigral degeneration (multiple system atrophy).

Journal: Acta neuropathologica 20050201

Title: Different apoptotic mechanisms are involved in the antiproliferative effects of 7beta-hydroxysitosterol and 7beta-hydroxycholesterol in human colon cancer cells.

Journal: Cell death and differentiation 20050201

Title: Differentiation of human monocytic cell lines confers susceptibility to Bacillus anthracis lethal toxin.

Journal: Cellular microbiology 20050201

Title: Silymarin induces apoptosis primarily through a p53-dependent pathway involving Bcl-2/Bax, cytochrome c release, and caspase activation.

Journal: Molecular cancer therapeutics 20050201

Title: Induction of caspase-independent apoptosis in H9c2 cardiomyocytes by adriamycin treatment.

Journal: Molecular and cellular biochemistry 20050201

Title: Sulindac sulfide-induced apoptosis in sinonasal cancer cells.

Journal: Acta oto-laryngologica 20050201

Title: 4-hydroxymethyl-1,6,8-trimethylfuro[2,3-h]quinolin-2(1H)-one induces mitochondrial dysfunction and apoptosis upon its intracellular oxidation.

Journal: Journal of medicinal chemistry 20050113

Title: CD95 apoptosis resistance in certain cells can be overcome by noncanonical activation of caspase-8.

Journal: Cell death and differentiation 20050101

Title: TNF receptor 1 is involved in the induction of apoptosis by the cyclin dependent kinase inhibitor p27Kip1 in the prostate cancer cell line PC-3.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050101

Title: Apoptosis inhibition plays a greater role than necrosis inhibition in decreasing bacterial translocation in experimental intestinal transplantation.

Journal: Surgery 20050101

Title: Caspase-independent retinal ganglion cell death after target ablation in the neonatal rat.

Journal: The European journal of neuroscience 20050101

Title: Induction of caspase-dependent, p53-mediated apoptosis by apigenin in human neuroblastoma.

Journal: Molecular cancer therapeutics 20050101

Title: A generalized caspase inhibitor disrupts early mammalian development.

Journal: The International journal of developmental biology 20050101

Title: Short-term culture with the caspase inhibitor z-VAD.fmk reduces beta cell apoptosis in transplanted islets and improves the metabolic outcome of the graft.

Journal: Cell transplantation 20050101

Title: Ellagic acid induced p53/p21 expression, G1 arrest and apoptosis in human bladder cancer T24 cells.

Journal: Anticancer research 20050101

Title: Human squamous cell carcinoma of the tongue and colon undergoes apoptosis upon phagocytosis of Saccharomyces cerevisiae, the baker's yeast, in vitro.

Journal: Anticancer research 20050101

Title: Tanshinone IIA isolated from Salvia miltiorrhiza elicits the cell death of human endothelial cells.

Journal: Journal of biomedical science 20050101

Title: Proteasome inhibitors abolish cell death downstream of caspase activation during anti-microtubule drug-induced apoptosis in leukemia cells.

Journal: Anticancer research 20050101

Title: Caspase-3 activation and induction of PARP cleavage by cyclic dipeptide cyclo(Phe-Pro) in HT-29 cells.

Journal: Anticancer research 20050101

Title: Preapoptotic chromatin condensation upstream of the mitochondrial checkpoint.

Journal: The Journal of biological chemistry 20041231

Title: Role of p53 in cisplatin-induced tubular cell apoptosis: dependence on p53 transcriptional activity.

Journal: American journal of physiology. Renal physiology 20041201

Title: The contraction phase of virus-specific CD8+ T cells is unaffected by a pan-caspase inhibitor.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20041201

Title: Chemotherapy-induced cell death in primary cerebellar granule neurons but not in astrocytes: in vitro paradigm of differential neurotoxicity.

Journal: Journal of neurochemistry 20041201

Title: Acute renal failure in endotoxemia is dependent on caspase activation.

Journal: Journal of the American Society of Nephrology : JASN 20041201

Title: Using a small molecule inhibitor of peptide: N-glycanase to probe its role in glycoprotein turnover.

Journal: Chemistry & biology 20041201

Title: Alterations in protein expression in HL-60 cells during etoposide-induced apoptosis modulated by the caspase inhibitor ZVAD.fmk.

Journal: Annals of the New York Academy of Sciences 20041201

Title: Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death.

Journal: The Journal of biological chemistry 20041119

Title: The effects of taurolidine, a novel antineoplastic agent, on human malignant mesothelioma.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041115

Title: Effects of glycolic acid on the induction of apoptosis via caspase-3 activation in human leukemia cell line (HL-60).

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20041101

Title: Increased sensitivity of early apoptotic cells to complement-mediated lysis.

Journal: European journal of immunology 20041101

Title: Khat (Catha edulis)-induced apoptosis is inhibited by antagonists of caspase-1 and -8 in human leukaemia cells.

Journal: British journal of cancer 20041101

Title: Plakin proteins are coordinately cleaved during apoptosis but preferentially through the action of different caspases.

Journal: Experimental dermatology 20041101

Title: Butyrate increases apoptosis induced by different antineoplastic drugs in monocytic leukemia cells.

Journal: Chemotherapy 20041101

Title: Capsaicin-induced apoptosis and reduced release of reactive oxygen species in MBT-2 murine bladder tumor cells.

Journal: Archives of pharmacal research 20041101

Title: Involvement of Sox-4 in the cytochrome c-dependent AIF-independent apoptotic pathway in HeLa cells induced by Delta12-prostaglandin J2.

Journal: Experimental & molecular medicine 20041031

Title: Molecular mechanism of diclofenac-induced apoptosis of promyelocytic leukemia: dependency on reactive oxygen species, Akt, Bid, cytochrome and caspase pathway.

Journal: Free radical biology & medicine 20041015

Title: Caspase inhibition blocks human T cell proliferation by suppressing appropriate regulation of IL-2, CD25, and cell cycle-associated proteins.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20041015

Title: Diallyl disulfide (DADS) induced apoptosis undergo caspase-3 activity in human bladder cancer T24 cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20041001

Title: Neurovascular protection reduces early brain injury after subarachnoid hemorrhage.

Journal: Stroke 20041001

Title: 17beta-estradiol reduces cardiomyocyte apoptosis in vivo and in vitro via activation of phospho-inositide-3 kinase/Akt signaling.

Journal: Circulation research 20041001

Title: Necrosis, apoptosis and hybrid death in the cortex and thalamus after barrel cortex ischemia in rats.

Journal: Brain research 20041001

Title: Fas/FasL-mediated apoptosis in perinatal murine lungs.

Journal: American journal of physiology. Lung cellular and molecular physiology 20041001

Title: Hydrostatic pressure induces apoptosis in the human leukaemic T-cell line Jurkat via the mitochondrial pathway.

Journal: Scandinavian journal of immunology 20041001

Title: Reduced oncotic necrosis in Fas receptor-deficient C57BL/6J-lpr mice after bile duct ligation.

Journal: Hepatology (Baltimore, Md.) 20041001

Title: Cytoskeletal rearrangement and caspase activation in sphingosine 1-phosphate-induced lung capillary tube formation.

Journal: Stem cells and development 20041001

Title: Nucling recruits Apaf-1/pro-caspase-9 complex for the induction of stress-induced apoptosis.

Journal: The Journal of biological chemistry 20040924

Title: Oxidative stress-induced apoptosis in retinal photoreceptor cells is mediated by calpains and caspases and blocked by the oxygen radical scavenger CR-6.

Journal: The Journal of biological chemistry 20040917

Title: An evolutionary conserved pathway of nuclear factor-kappaB activation involving caspase-mediated cleavage and N-end rule pathway-mediated degradation of IkappaBalpha.

Journal: The Journal of biological chemistry 20040917

Title: Retinoic acid increases the expression of p53 and proapoptotic caspases and sensitizes keratinocytes to apoptosis: a possible explanation for tumor preventive action of retinoids.

Journal: Cancer research 20040915

Title: Phosphatidylinositol-3 kinase/Akt and GSK-3 mediated cytoprotective effect of epigallocatechin gallate on oxidative stress-injured neuronal-differentiated N18D3 cells.

Journal: Neurotoxicology 20040901

Title: Noncytotoxic ribonuclease, RNase T1, induces tumor cell death via hemagglutinating virus of Japan envelope vector.

Journal: European journal of biochemistry 20040901

Title: Caspase inhibitor Z-VAD-FMK potentiates heat shock-induced apoptosis and HSP70 synthesis in macrophages.

Journal: Bulletin of experimental biology and medicine 20040901

Title: Modulation of the Omi/HtrA2 signaling pathway after transient focal cerebral ischemia in mouse brains that overexpress SOD1.

Journal: Brain research. Molecular brain research 20040823

Title: Acetone extract of Angelica sinensis inhibits proliferation of human cancer cells via inducing cell cycle arrest and apoptosis.

Journal: Life sciences 20040813

Title: Involvement of caspase-10 in advanced glycation end-product-induced apoptosis of bovine retinal pericytes in culture.

Journal: Biochimica et biophysica acta 20040804

Title: H(2)O(2) inhibits alveolar epithelial wound repair in vitro by induction of apoptosis.

Journal: American journal of physiology. Lung cellular and molecular physiology 20040801

Title: Role of caspase in CD80 expression of superantigen-stimulated monocytes.

Journal: International journal of molecular medicine 20040801

Title: Voltage-gated K+ current: a marker for apoptosis in differentiating neuronal progenitor cells?

Journal: The European journal of neuroscience 20040801

Title: Caspases mediate processing of the capsid precursor and cell release of human astroviruses.

Journal: Journal of virology 20040801

Title: Diosgenin induces apoptosis in HeLa cells via activation of caspase pathway.

Journal: Acta pharmacologica Sinica 20040801

Title: In vitro cytotoxicity of orthodontic archwires in cortical cell cultures.

Journal: European journal of orthodontics 20040801

Title: Abrin induces HeLa cell apoptosis by cytochrome c release and caspase activation.

Journal: Journal of biochemistry and molecular biology 20040731

Title: Isolation and characterization of a novel pituitary tumor apoptosis gene.

Journal: Molecular endocrinology (Baltimore, Md.) 20040701

Title: Inhibitors of cysteine cathepsin and calpain do not prevent ultraviolet-B-induced apoptosis in human keratinocytes and HeLa cells.

Journal: Archives of dermatological research 20040701

Title: WR-1065, the active form of amifostine, protects HL-60 cells but not peripheral blood mononuclear cells from radiation and etoposide-induced apoptosis.

Journal: International journal of radiation oncology, biology, physics 20040701

Title: LPS-induced apoptosis is dependent upon mitochondrial dysfunction.

Journal: Apoptosis : an international journal on programmed cell death 20040701

Title: GRP94 reduces cell death in SH-SY5Y cells perturbated calcium homeostasis.

Journal: Apoptosis : an international journal on programmed cell death 20040701

Title: When cells die II: a comprehensive evaluation of apoptosis and programmed cell death.

Journal: Cell death and differentiation 20040701

Title: The spread of cell death from impact damaged cartilage: lack of evidence for the role of nitric oxide and caspases.

Journal: Osteoarthritis and cartilage 20040701

Title: Combination of isoflurane and caspase inhibition reduces cerebral injury in rats subjected to focal cerebral ischemia.

Journal: Anesthesiology 20040701

Title: Developmental differences in HO-induced oligodendrocyte cell death: role of glutathione, mitogen-activated protein kinases and caspase 3.

Journal: Journal of neurochemistry 20040701

Title: Selenite-induced p53 Ser-15 phosphorylation and caspase-mediated apoptosis in LNCaP human prostate cancer cells.

Journal: Molecular cancer therapeutics 20040701

Title: Inducible nitric oxide synthase in T cells regulates T cell death and immune memory.

Journal: The Journal of clinical investigation 20040615

Title: Renal carcinoma cells undergo apoptosis without oligonucleosomal DNA fragmentation.

Journal: Biochemical and biophysical research communications 20040604

Title: The apoptotic and necrotic effects of tomatine adjuvant.

Journal: Vaccine 20040602

Title: Caspase-dependent cytochrome c release and cell death in chick cardiomyocytes after simulated ischemia-reperfusion.

Journal: American journal of physiology. Heart and circulatory physiology 20040601

Title: Apoptosis inhibition in P. aeruginosa-induced lung injury influences lung fluid balance.

Journal: Intensive care medicine 20040601

Title: Na+/K+ pump and endothelial cell survival: [Na+]i/[K+]i-independent necrosis triggered by ouabain, and protection against apoptosis mediated by elevation of [Na+]i.

Journal: Pflugers Archiv : European journal of physiology 20040601

Title: Inhibition of caspase-mediated PARP-1 cleavage results in increased necrosis in isolated islets of Langerhans.

Journal: Journal of molecular medicine (Berlin, Germany) 20040601

Title: In vivo induction of endothelial apoptosis leads to vessel thrombosis and endothelial denudation: a clue to the understanding of the mechanisms of thrombotic plaque erosion.

Journal: Circulation 20040601

Title: Susceptibility of mouse primary cortical neuronal cells to coxsackievirus B.

Journal: The Journal of general virology 20040601

Title: Gene expression profile of inflammatory neutrophils: alterations in the inhibitors of apoptosis proteins during spontaneous and delayed apoptosis.

Journal: Shock (Augusta, Ga.) 20040601

Title: Apoptosis is not an invariable component of in vitro models of cortical cerebral ischaemia.

Journal: Cell research 20040601

Title: The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe.

Journal: Oncogene 20040527

Title: Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy.

Journal: Oncogene 20040527

Title: Down-regulation of apoptosis-inducing factor protein by RNA interference inhibits UVA-induced cell death.

Journal: Biochemical and biophysical research communications 20040514

Title: Staining of human sperm with fluorochrome-labeled inhibitor of caspases to detect activated caspases: correlation with apoptosis and sperm parameters.

Journal: Human reproduction (Oxford, England) 20040501

Title: Induction of apoptosis by the proteasome inhibitor MG132 in human HCC cells: Possible correlation with specific caspase-dependent cleavage of beta-catenin and inhibition of beta-catenin-mediated transactivation.

Journal: International journal of molecular medicine 20040501

Title: Phosphatidylserine efflux and intercellular fusion in a BeWo model of human villous cytotrophoblast.

Journal: Placenta 20040501

Title: Pro-Th1 cytokines promote Fas-dependent apoptosis of immature peripheral basophils.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20040501

Title: Cathepsin-dependent apoptosis triggered by supraoptimal activation of T lymphocytes: a possible mechanism of high dose tolerance.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20040501

Title: Myocyte contractility with caspase inhibition and simulated hyperkalemic cardioplegic arrest.

Journal: The Annals of thoracic surgery 20040501

Title: Caspase inhibitors attenuate superantigen-induced inflammatory cytokines, chemokines, and T-cell proliferation.

Journal: Clinical and diagnostic laboratory immunology 20040501

Title: Role of caspase activation in butyrate-induced terminal differentiation of HT29 colon carcinoma cells.

Journal: Archives of biochemistry and biophysics 20040415

Title: Thalidomide induces apoptosis in human monocytes by using a cytochrome c-dependent pathway.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20040415

Title: Neurotoxicity of amphetamine derivatives is mediated by caspase pathway activation in rat cerebellar granule cells.

Journal: Toxicology and applied pharmacology 20040415

Title: A cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in human cells.

Journal: The Journal of biological chemistry 20040409

Title: Essential role of caspases in epigallocatechin-3-gallate-mediated inhibition of nuclear factor kappa B and induction of apoptosis.

Journal: Oncogene 20040401

Title: Potassium attenuates zinc-induced death of cultured cortical astrocytes.

Journal: Glia 20040401

Title: The insecticidal toxin Makes caterpillars floppy (Mcf) promotes apoptosis in mammalian cells.

Journal: Cellular microbiology 20040401

Title: Staurosporine-induced apoptosis in Chang liver cells is associated with down-regulation of Bcl-2 and Bcl-XL.

Journal: International journal of molecular medicine 20040401

Title: N-terminal fragment of c-FLIP(L) processed by caspase 8 specifically interacts with TRAF2 and induces activation of the NF-kappaB signaling pathway.

Journal: Molecular and cellular biology 20040401

Title: Caspase-3-mediated apoptosis of human eosinophils by the tissue-invading helminth Paragonimus westermani.

Journal: International archives of allergy and immunology 20040401

Title: 5-fluorouracil-induced oligodendrocyte death and inhibitory effect of cycloheximide, Trolox, and Z-VAD-FMK in murine cortical culture.

Journal: Cancer 20040401

Title: Protein kinase B/Akt regulates coxsackievirus B3 replication through a mechanism which is not caspase dependent.

Journal: Journal of virology 20040401

Title: The histone deacetylase inhibitor suberic bishydroxamate regulates the expression of multiple apoptotic mediators and induces mitochondria-dependent apoptosis of melanoma cells.

Journal: Molecular cancer therapeutics 20040401

Title: LIGHT sensitizes IFN-gamma-mediated apoptosis of HT-29 human carcinoma cells through both death receptor and mitochondria pathways.

Journal: Cell research 20040401

Title: A novel mechanism for imatinib mesylate-induced cell death of BCR-ABL-positive human leukemic cells: caspase-independent, necrosis-like programmed cell death mediated by serine protease activity.

Journal: Blood 20040315

Title: Overexpression of phospholipase D prevents actinomycin D-induced apoptosis through potentiation of phosphoinositide 3-kinase signalling pathways in Chinese-hamster ovary cells.

Journal: The Biochemical journal 20040301

Title: Caspase inhibition switches the mode of cell death induced by cyanide by enhancing reactive oxygen species generation and PARP-1 activation.

Journal: Toxicology and applied pharmacology 20040301

Title: NuMA and nuclear lamins are cleaved during viral infection--inhibition of caspase activity prevents cleavage and rescues HeLa cells from measles virus-induced but not from rhinovirus 1B-induced cell death.

Journal: Virology 20040301

Title: The oncostatin M receptor/gp130 ligand murine oncostatin M induces apoptosis in adrenocortical Y-1 tumor cells.

Journal: The Journal of endocrinology 20040301

Title: The neurotoxicant trimethyltin induces apoptosis via caspase activation, p38 protein kinase, and oxidative stress in PC12 cells.

Journal: Toxicology letters 20040227

Title: Crystal structure of an invertebrate caspase.

Journal: The Journal of biological chemistry 20040220

Title: Tumor necrosis factor-related apoptosis-inducing ligand cooperates with anticancer drugs to overcome chemoresistance in antiapoptotic Bcl-2 family members expressing jurkat cells.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040215

Title: 2-methoxyestradiol induces caspase-independent, mitochondria-centered apoptosis in DS-sarcoma cells.

Journal: International journal of cancer 20040210

Title: Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective.

Journal: The Journal of biological chemistry 20040206

Title: Crosstalk between nitric oxide and zinc pathways to neuronal cell death involving mitochondrial dysfunction and p38-activated K+ channels.

Journal: Neuron 20040205

Title: Caspase-dependent apoptosis and -independent poly(ADP-ribose) polymerase cleavage induced by transforming growth factor beta1.

Journal: The international journal of biochemistry & cell biology 20040201

Title: Induction of apoptosis by bleomycin in p53-null HL-60 leukemia cells.

Journal: International journal of oncology 20040201

Title: Achacin induces cell death in HeLa cells through two different mechanisms.

Journal: Archives of biochemistry and biophysics 20040201

Title: Mediating of caspase-independent apoptosis by cadmium through the mitochondria-ROS pathway in MRC-5 fibroblasts.

Journal: Journal of cellular biochemistry 20040201

Title: Rescue of defective branching nephrogenesis in renal-coloboma syndrome by the caspase inhibitor, Z-VAD-fmk.

Journal: Journal of the American Society of Nephrology : JASN 20040201

Title: A ginseng saponin metabolite-induced apoptosis in HepG2 cells involves a mitochondria-mediated pathway and its downstream caspase-8 activation and Bid cleavage.

Journal: Toxicology and applied pharmacology 20040201

Title: Increase of nuclear ceramide through caspase-3-dependent regulation of the 'sphingomyelin cycle' in Fas-induced apoptosis.

Journal: Cancer research 20040201

Title: Induction of cell death by saponin and antigen delivery.

Journal: Pharmaceutical research 20040201

Title: Modulation of ATP levels alters the mode of hydrogen peroxide-induced cell death in primary cortical cultures: effects of putative neuroprotective agents.

Journal: Brain research 20040130

Title: Carbon monoxide inhibits T lymphocyte proliferation via caspase-dependent pathway.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20040115

Title: CEACAM6 gene silencing impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cells.

Journal: Oncogene 20040115

Title: Antirestenotic effects of a locally delivered caspase inhibitor in a balloon injury model.

Journal: Circulation 20040106

Title: Oxidative stress induces p53-mediated apoptosis in glia: p53 transcription-independent way to die.

Journal: Journal of neuroscience research 20040101

Title: Peroxynitrite-induced apoptosis in photoreceptor cells.

Journal: Current eye research 20040101

Title: Apoptosis in serum-deprived vascular smooth muscle cells: evidence for cell volume-independent mechanism.

Journal: Apoptosis : an international journal on programmed cell death 20040101

Title: Inhibitors directed towards caspase-1 and -3 are less effective than pan caspase inhibition in preventing renal proximal tubular cell apoptosis.

Journal: Nephron. Experimental nephrology 20040101

Title: Recent advances in the imaging of programmed cell death.

Journal: Current pharmaceutical design 20040101

Title: Caspase inhibition decreases both platelet phosphatidylserine exposure and aggregation: caspase inhibition of platelets.

Journal: Thrombosis research 20040101

Title: Monocytes stimulated with group B streptococci or interferons release tumour necrosis factor-related apoptosis-inducing ligand.

Journal: Scandinavian journal of immunology 20040101

Title: Release of DNA from dead and dying lymphocyte and monocyte cell lines in vitro.

Journal: Scandinavian journal of immunology 20040101

Title: The c-Jun N-terminal kinase 1 activity is differentially regulated by specific mechanisms during apoptosis.

Journal: The Journal of biological chemistry 20031212

Title: Involvement of Akt in mitochondria-dependent apoptosis induced by a cdc25 phosphatase inhibitor naphthoquinone analog.

Journal: FEBS letters 20031204

Title: Caspase activation during Haemophilus somnus lipooligosaccharide-mediated apoptosis of bovine endothelial cells.

Journal: Microbial pathogenesis 20031201

Title: Intracellular determination of activated caspases (IDAC) by flow cytometry using a pancaspase inhibitor labeled with FITC.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20031201

Title: Apoptosis-mediated selective killing of malignant cells by cardiac steroids: maintenance of cytotoxicity and loss of cardiac activity of chemically modified derivatives.

Journal: International immunopharmacology 20031201

Title: Growth factor deprivation induces an alternative non-apoptotic death mechanism that is inhibited by Bcl2 in cells derived from neural precursor cells.

Journal: Journal of hematotherapy & stem cell research 20031201

Title: 15-Deoxy-delta12,14-prostaglandin J2, a ligand for peroxisome proliferators-activated receptor-gamma, induces apoptosis in human hepatoma cells.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20031201

Title: A novel tumor suppressor protein promotes keratinocyte terminal differentiation via activation of type I transglutaminase.

Journal: The Journal of biological chemistry 20031128

Title: The CD99 signal enhances Fas-mediated apoptosis in the human leukemic cell line, Jurkat.

Journal: FEBS letters 20031120

Title: Alveolar macrophage apoptosis contributes to pneumococcal clearance in a resolving model of pulmonary infection.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20031115

Title: No caspase activation but overexpression of Bcl-2 in bovine cells infected with noncytopathic bovine virus diarrhoea virus.

Journal: Veterinary microbiology 20031107

Title: Staphylococcus aureus alpha-toxin-induced cell death: predominant necrosis despite apoptotic caspase activation.

Journal: Cell death and differentiation 20031101

Title: Lethal toxin from Clostridium sordellii induces apoptotic cell death by disruption of mitochondrial homeostasis in HL-60 cells.

Journal: Cellular microbiology 20031101

Title: Induction of apoptosis without redox catastrophe by thioredoxin-inhibitory compounds.

Journal: Biochemical pharmacology 20031101

Title: Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein.

Journal: The EMBO journal 20031015

Title: The DNA damage-induced decrease of Bcl-2 is secondary to the activation of apoptotic effector caspases.

Journal: Oncogene 20031009

Title: Progesterone-induced apoptosis in immortalized normal and malignant human ovarian surface epithelial cells involves enhanced expression of FasL.

Journal: Oncogene 20031009

Title: Neuroprotective action of flavopiridol, a cyclin-dependent kinase inhibitor, in colchicine-induced apoptosis.

Journal: Neuropharmacology 20031001

Title: Staphylococcus aureus alpha-toxin induces apoptosis in peripheral blood mononuclear cells: role of endogenous tumour necrosis factor-alpha and the mitochondrial death pathway.

Journal: Cellular microbiology 20031001

Title: Inhibition of chondrocyte apoptosis in vivo following acute osteochondral injury.

Journal: Osteoarthritis and cartilage 20031001

Title: Heat stress downregulates FLIP and sensitizes cells to Fas receptor-mediated apoptosis.

Journal: Cell death and differentiation 20031001

Title: Serine proteases mediate apoptosis-like cell death and phagocytosis under caspase-inhibiting conditions.

Journal: Cell death and differentiation 20031001

Title: A serine protease is involved in the initiation of DNA damage-induced apoptosis.

Journal: Cell death and differentiation 20031001

Title: Apoptosis in human oral squamous cell carcinomas is induced by 15-deoxy-delta 12,14-prostaglandin J2 but not by troglitazone.

Journal: Journal of dental research 20031001

Title: A role for caspase-1 in serum withdrawal-induced apoptosis of endothelial cells.

Journal: Laboratory investigation; a journal of technical methods and pathology 20031001

Title: Amplification of a reactive oxygen species signal in axotomized retinal ganglion cells.

Journal: Antioxidants & redox signaling 20031001

Title: Neurotoxicity induced by amyloid beta-peptide and ibotenic acid in organotypic hippocampal cultures: protection by S-allyl-L-cysteine, a garlic compound.

Journal: Brain research 20030919

Title: Protein kinase C inhibition induces DNA fragmentation in COLO 205 cells which is blocked by cysteine protease inhibition but not mediated through caspase-3.

Journal: Experimental cell research 20030910

Title: Influenza A virus-induced apoptosis in bronchiolar epithelial (NCI-H292) cells limits pro-inflammatory cytokine release.

Journal: The Journal of general virology 20030901

Title: The Bcl-2 family pro-apoptotic molecule, BNIP3 regulates activation-induced cell death of effector cytotoxic T lymphocytes.

Journal: Immunology 20030901

Title: Involvement of mitochondria in acetaminophen-induced apoptosis and hepatic injury: roles of cytochrome c, Bax, Bid, and caspases.

Journal: Toxicology and applied pharmacology 20030901

Title: Nitric oxide-mediated inhibition of caspase-dependent T lymphocyte proliferation.

Journal: Journal of leukocyte biology 20030901

Title: Adenoviral natural born killer gene therapy for malignant glioma.

Journal: Human gene therapy 20030901

Title: Mac-1 and Fas activities are concurrently required for execution of smooth muscle cell death by M-CSF-stimulated macrophages.

Journal: Cardiovascular research 20030901

Title: Kahalalide F, a new marine-derived compound, induces oncosis in human prostate and breast cancer cells.

Journal: Molecular cancer therapeutics 20030901

Title: Effects of Ginko Biloba and caspase inhibitors on brain ischemia in the Mongolian Gerbil.

Journal: Journal of neurosurgical sciences 20030901

Title: TRAIL activates a caspase 9/7-dependent pathway in caspase 8/10-defective SK-N-SH neuroblastoma cells with two functional end points: induction of apoptosis and PGE2 release.

Journal: Neoplasia (New York, N.Y.) 20030901

Title: Regulation of the growth arrest and DNA damage-inducible gene 45 (GADD45) by peroxisome proliferator-activated receptor gamma in vascular smooth muscle cells.

Journal: Circulation research 20030822

Title: Inhibition of apoptosis by Z-VAD-fmk in SMN-depleted S2 cells.

Journal: The Journal of biological chemistry 20030815

Title: Bcl-2 and Bcl-xL overexpression inhibits cytochrome c release, activation of multiple caspases, and virus release following coxsackievirus B3 infection.

Journal: Virology 20030815

Title: Synergistic antiproliferative and apoptotic effects induced by epidermal growth factor receptor and protein kinase a inhibitors in human prostatic cancer cell lines.

Journal: International journal of cancer 20030810

Title: Insulin-like growth factor-binding protein-5 inhibits the growth of human breast cancer cells in vitro and in vivo.

Journal: The Journal of biological chemistry 20030808

Title: Q-VD-OPh, a broad spectrum caspase inhibitor with potent antiapoptotic properties.

Journal: Apoptosis : an international journal on programmed cell death 20030801

Title: Inhibition of topoisomerase II overrides the G2/M check points of the cell cycle in EBV-lymphocytes.

Journal: Apoptosis : an international journal on programmed cell death 20030801

Title: Nanosecond, high-intensity pulsed electric fields induce apoptosis in human cells.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030801

Title: Loss of mitochondrial transmembrane potential and caspase-9 activation during apoptosis induced by the novel styryl-lactone goniothalamin in HL-60 leukemia cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20030801

Title: Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity.

Journal: Cell death and differentiation 20030801

Title: Control of erythroid cell production via caspase-mediated cleavage of transcription factor SCL/Tal-1.

Journal: Cell death and differentiation 20030801

Title: Induction of apoptosis in human osteosarcoma Saos-2 cells by the proteasome inhibitor MG132 and the protective effect of pRb.

Journal: Cell death and differentiation 20030801

Title: Prevalence of necrosis in C2-ceramide-induced cytotoxicity in NB16 neuroblastoma cells.

Journal: Molecular pharmacology 20030801

Title: Involvement of oxidative stress in apoptosis induced by a mixture of isothiazolinones in normal human keratinocytes.

Journal: The Journal of investigative dermatology 20030801

Title: MHC class II-mediated apoptosis in dendritic cells: a role for membrane-associated and mitochondrial signaling pathways.

Journal: International immunology 20030801

Title: Caspase-dependent and -independent apoptosis of mast cells induced by withdrawal of IL-3 is prevented by Toll-like receptor 4-mediated lipopolysaccharide stimulation.

Journal: European journal of immunology 20030801

Title: Entry into the stationary phase is associated with a rapid loss of viability and an apoptotic-like phenotype in the opportunistic pathogen Aspergillus fumigatus.

Journal: Fungal genetics and biology : FG & B 20030801

Title: Magnolol induces apoptosis in vascular smooth muscle.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20030801

Title: Novel mechanisms of apoptosis induced by histone deacetylase inhibitors.

Journal: Cancer research 20030801

Title: Flow cytometry characterization of white cell-reduced blood: apoptosis markers and morphology of postfiltration elements.

Journal: Vox sanguinis 20030801

Title: Expression of CD10 by B-chronic lymphocytic leukemia cells undergoing apoptosis in vivo and in vitro.

Journal: Haematologica 20030801

Title: Apoptosis of Theileria-infected lymphocytes induced upon parasite death involves activation of caspases 9 and 3.

Journal: Biochimie 20030801

Title: Expression of dengue ApoptoM sequence results in disruption of mitochondrial potential and caspase activation.

Journal: Biochimie 20030801

Title: Effect of PSC 833, a potent inhibitor of P-glycoprotein, on the growth of astrocytoma cells in vitro.

Journal: Cancer letters 20030730

Title: The p17 cleaved form of caspase-3 is present within viable macrophages in vitro and in atherosclerotic plaque.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20030701

Title: Etoposide upregulates Bax-enhancing tumour necrosis factor-related apoptosis inducing ligand-mediated apoptosis in the human hepatocellular carcinoma cell line QGY-7703.

Journal: European journal of biochemistry 20030701

Title: Paraoxon induces apoptosis in EL4 cells via activation of mitochondrial pathways.

Journal: Toxicology and applied pharmacology 20030701

Title: MPA increases idarubicin-induced apoptosis in chronic lymphatic leukaemia cells via caspase-3.

Journal: Journal of cellular biochemistry 20030701

Title: Proteases associated with programmed cell death of megagametophyte cells after germination of white spruce (Picea glauca) seeds.

Journal: Plant molecular biology 20030701

Title: Triggering of apoptosis is not sufficient to induce human immunodeficiency virus gene expression.

Journal: IUBMB life 20030701

Title: Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine.

Journal: Oncogene 20030619

Title: Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation.

Journal: Genes & development 20030615

Title: Caspase activity is required for stimulated B lymphocytes to enter the cell cycle.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20030615

Title: Leptin induces apoptosis via ERK/cPLA2/cytochrome c pathway in human bone marrow stromal cells.

Journal: The Journal of biological chemistry 20030613

Title: LIGHT sensitizes IFNgamma-mediated apoptosis of MDA-MB-231 breast cancer cells leading to down-regulation of anti-apoptosis Bcl-2 family members.

Journal: Cancer letters 20030610

Title: Inhibition of phosphatidylinositol 3-kinase sensitizes vascular endothelial cells to cytokine-initiated cathepsin-dependent apoptosis.

Journal: The Journal of biological chemistry 20030606

Title: Apoptosis triggered redistribution of caspase-9 from cytoplasm to mitochondria.

Journal: FEBS letters 20030605

Title: deltaNp63alpha functions as both a positive and a negative transcriptional regulator and blocks in vitro differentiation of murine keratinocytes.

Journal: Oncogene 20030605

Title: Orphan nuclear receptor Nur77 is involved in caspase-independent macrophage cell death.

Journal: The Journal of experimental medicine 20030602

Title: Recovery of hepatocellular ATP and 'pericentral apoptosis' after hemorrhage and resuscitation.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030601

Title: Involvement of apoptosis and calcium mobilization in tetrahydrobiopterin-induced dopaminergic cell death.

Journal: Experimental neurology 20030601

Title: Antineoplastic ribonucleases selectively kill thyroid carcinoma cells via caspase-mediated induction of apoptosis.

Journal: The Journal of clinical endocrinology and metabolism 20030601

Title: Effects of oxidative stress on human erythroid colony formation: Modulation by gamma-interferon.

Journal: The Journal of laboratory and clinical medicine 20030601

Title: Calpain facilitates the neuron death induced by 3-nitropropionic acid and contributes to the necrotic morphology.

Journal: Journal of neuropathology and experimental neurology 20030601

Title: Cloning of zebrafish BAD, a BH3-only proapoptotic protein, whose overexpression leads to apoptosis in COS-1 cells and zebrafish embryos.

Journal: Biochemical and biophysical research communications 20030516

Title: Mitochondria-mediated caspase-independent apoptosis induced by cadmium in normal human lung cells.

Journal: Journal of cellular biochemistry 20030515

Title: Caspase inhibition switches doxorubicin-induced apoptosis to senescence.

Journal: Oncogene 20030508

Title: The role of apoptosis signal-regulating kinase 1 in lymphotoxin-beta receptor-mediated cell death.

Journal: The Journal of biological chemistry 20030502

Title: TNF-related apoptosis-inducing ligand (TRAIL) frequently induces apoptosis in Philadelphia chromosome-positive leukemia cells.

Journal: Blood 20030501

Title: Acadesine activates AMPK and induces apoptosis in B-cell chronic lymphocytic leukemia cells but not in T lymphocytes.

Journal: Blood 20030501

Title: Neuregulin promotes autophagic cell death of prostate cancer cells.

Journal: The Prostate 20030501

Title: Induction of cellular necrosis by the glutathione peroxidase mimetic ebselen.

Journal: Journal of cellular biochemistry 20030501

Title: A distinct death mechanism is induced by 1-methyl-4-phenylpyridinium or by 6-hydroxydopamine in cultured rat cortical neurons: degradation and dephosphorylation of tau.

Journal: Neuroscience letters 20030501

Title: Alveolar wall apoptosis causes lung destruction and emphysematous changes.

Journal: American journal of respiratory cell and molecular biology 20030501

Title: Nitric oxide inhibits polyamine-induced apoptosis in the human extravillous trophoblast cell line SGHPL-4.

Journal: Human reproduction (Oxford, England) 20030501

Title: Induction of autophagic cell death in malignant glioma cells by arsenic trioxide.

Journal: Cancer research 20030501

Title: Induction of apoptosis in human lymphocytes by human anti-HLA class I antibodies.

Journal: Transplantation 20030427

Title: The lysophospholipid receptor G2A activates a specific combination of G proteins and promotes apoptosis.

Journal: The Journal of biological chemistry 20030418

Title: Caspase-dependent cell death mediates the early phase of aortic hypertrophy regression in losartan-treated spontaneously hypertensive rats.

Journal: Circulation research 20030418

Title: Two phases of signalling between mitochondria during apoptosis leading to early depolarisation and delayed cytochrome c release.

Journal: Journal of cell science 20030415

Title: Caspase inhibition shifts neuroepithelioma cell response to okadaic acid from apoptosis to an apoptotic-like form of death.

Journal: Biochemical and biophysical research communications 20030404

Title: Efficacy of the anticaspase agent zVAD-fmk on post-thaw viability of canine spermatozoa.

Journal: Theriogenology 20030401

Title: Galectin-9 induces apoptosis through the calcium-calpain-caspase-1 pathway.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20030401

Title: Caspase inhibition causes hyperacute tumor necrosis factor-induced shock via oxidative stress and phospholipase A2.

Journal: Nature immunology 20030401

Title: Creating conditions similar to those that occur during exposure of cells to microgravity induces apoptosis in human lymphocytes by 5-lipoxygenase-mediated mitochondrial uncoupling and cytochrome c release.

Journal: Journal of leukocyte biology 20030401

Title: IL-7 inhibits dexamethasone-induced apoptosis via Akt/PKB in mature, peripheral T cells.

Journal: European journal of immunology 20030401

Title: Oxidized low-density lipoprotein sensitizes human vascular smooth muscle cells to FAS (CD95)-mediated apoptosis.

Journal: Clinical and experimental pharmacology & physiology 20030401

Title: AMP-activated protein kinase can induce apoptosis of insulin-producing MIN6 cells through stimulation of c-Jun-N-terminal kinase.

Journal: Journal of molecular endocrinology 20030401

Title: Caspase-dependent cleavage of tensin induces disruption of actin cytoskeleton during apoptosis.

Journal: Biochemical and biophysical research communications 20030328

Title: 5-Aminoimidazole-4-carboxamide riboside induces apoptosis in Jurkat cells, but the AMP-activated protein kinase is not involved.

Journal: The Biochemical journal 20030315

Title: A broad-spectrum caspase inhibitor attenuates allergic airway inflammation in murine asthma model.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20030315

Title: Effect of malathion on apoptosis of murine L929 fibroblasts: a possible mechanism for toxicity in low dose exposure.

Journal: Toxicology 20030314

Title: Neuroleukin inhibition sensitises neuronal cells to caspase-dependent apoptosis.

Journal: Biochemical and biophysical research communications 20030314

Title: Tumor necrosis factor alpha induces a caspase-independent death pathway in human neutrophils.

Journal: Blood 20030301

Title: Bax cleavage implicates caspase-dependent H2O2-induced apoptosis of hepatocytes.

Journal: International journal of molecular medicine 20030301

Title: Reactive oxygen species and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase mediate hyperoxia-induced cell death in lung epithelium.

Journal: American journal of respiratory cell and molecular biology 20030301

Title: Overexpression of the human inducible nitric oxide synthase gene enhances radiation-induced apoptosis in colorectal cancer cells via a caspase-dependent mechanism.

Journal: Nitric oxide : biology and chemistry 20030301

Title: Apoptosis-dependent acute lung injury and repair after intratracheal instillation of noradrenaline in rats.

Journal: Experimental physiology 20030301

Title: Z-FA-fmk inhibits effector caspases but not initiator caspases 8 and 10, and demonstrates that novel anticancer retinoid-related molecules induce apoptosis via the intrinsic pathway.

Journal: Molecular cancer therapeutics 20030301

Title: The late increase in intracellular free radical oxygen species during apoptosis is associated with cytochrome c release, caspase activation, and mitochondrial dysfunction.

Journal: Cell death and differentiation 20030301

Title: Inflammatory liver steatosis caused by IL-12 and IL-18.

Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20030301

Title: [3H]-thymidine labelling of DNA triggers apoptosis potentiated by E1A-adenoviral protein.

Journal: Apoptosis : an international journal on programmed cell death 20030301

Title: Colchicine induces apoptosis in organotypic hippocampal slice cultures.

Journal: Brain research 20030227

Title: Characterization of the transforming growth factor-beta 1-induced apoptotic transcriptome in FaO hepatoma cells.

Journal: The Journal of biological chemistry 20030221

Title: Protein kinase C-epsilon protects PC12 cells against methamphetamine-induced death: possible involvement of suppression of glutamate receptor.

Journal: Life sciences 20030221

Title: Induction of apoptosis in frog virus 3-infected cells.

Journal: Virology 20030215

Title: Study of caspase inhibitors for limiting death in mammalian cell culture.

Journal: Biotechnology and bioengineering 20030205

Title: Cholesteryl-hemisuccinate-induced apoptosis of promyelocytic leukemia HL-60 cells through a cyclosporin A-insensitive mechanism.

Journal: Biochemical pharmacology 20030201

Title: Palmitic and stearic fatty acids induce caspase-dependent and -independent cell death in nerve growth factor differentiated PC12 cells.

Journal: Journal of neurochemistry 20030201

Title: Phytosphingosine induces apoptotic cell death via caspase 8 activation and Bax translocation in human cancer cells.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030201

Title: A novel technique for inducing local inner ear damage.

Journal: Hearing research 20030201

Title: Progression of aortic valve stenosis: TGF-beta1 is present in calcified aortic valve cusps and promotes aortic valve interstitial cell calcification via apoptosis.

Journal: The Annals of thoracic surgery 20030201

Title: Secondary reactive oxygen species extend the range of photosensitization effects in cells: DNA damage produced via initial membrane photosensitization.

Journal: Photochemistry and photobiology 20030201

Title: Expression, purification, and characterization of caspases.

Journal: Current protocols in protein science 20030201

Title: Identification of apoptosis-inducing factor in human coronary artery endothelial cells.

Journal: Biochemical and biophysical research communications 20030131

Title: Ataxin-2 promotes apoptosis of human neuroblastoma cells.

Journal: Oncogene 20030123

Title: Infected cell protein No. 22 is subject to proteolytic cleavage by caspases activated by a mutant that induces apoptosis.

Journal: Virology 20030120

Title: Transcription-independent triggering of the extrinsic pathway of apoptosis by human papillomavirus 18 E2 protein.

Journal: Oncogene 20030116

Title: Monitoring of apoptosis of HL60 cells by Fourier-transform infrared spectroscopy.

Journal: The Biochemical journal 20030115

Title: Reperfusion, not simulated ischemia, initiates intrinsic apoptosis injury in chick cardiomyocytes.

Journal: American journal of physiology. Heart and circulatory physiology 20030101

Title: Broad-spectrum caspase inhibition paradoxically augments cell death in TNF-alpha -stimulated neutrophils.

Journal: Blood 20030101

Title: Fibroblast growth factor-inducible 14 mediates multiple pathways of TWEAK-induced cell death.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20030101

Title: Antiapoptotic effect of granulocyte colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, and cyclic AMP on human neutrophils: protein synthesis-dependent and protein synthesis-independent mechanisms and the role of the Janus kinase-STAT pathway.

Journal: International journal of hematology 20030101

Title: Protection of mature oligodendrocytes by inhibitors of caspases and calpains.

Journal: Neurochemical research 20030101

Title: Evodiamine, a constituent of Evodiae Fructus, induces anti-proliferating effects in tumor cells.

Journal: Cancer science 20030101

Title: Dieldrin induces apoptosis by promoting caspase-3-dependent proteolytic cleavage of protein kinase Cdelta in dopaminergic cells: relevance to oxidative stress and dopaminergic degeneration.

Journal: Neuroscience 20030101

Title: The molecular mechanism of arsenic trioxide-induced apoptosis and oncosis in leukemia/lymphoma cell lines.

Journal: Acta haematologica 20030101

Title: MAPK signaling is involved in camptothecin-induced cell death.

Journal: Molecules and cells 20021231

Title: NADPH oxidase-dependent oxidation and externalization of phosphatidylserine during apoptosis in Me2SO-differentiated HL-60 cells. Role in phagocytic clearance.

Journal: The Journal of biological chemistry 20021220

Title: Ordering ceramide-induced cell detachment and apoptosis in human neuroepithelioma.

Journal: Neuroscience letters 20021216

Title: Specific involvement of caspases in the differentiation of monocytes into macrophages.

Journal: Blood 20021215

Title: Induction of poly(ADP-ribose) polymerase-1 cleavage by antitumor triptycene bisquinones in wild-type and daunorubicin-resistant HL-60 cell lines.

Journal: Cancer letters 20021215

Title: The novel presenilin-1-associated protein is a proapoptotic mitochondrial protein.

Journal: The Journal of biological chemistry 20021213

Title: Cleavage of p21waf1 by proteinase-3, a myeloid-specific serine protease, potentiates cell proliferation.

Journal: The Journal of biological chemistry 20021206

Title: Purging effect of dibutyl phthalate on leukemia cells involves fas independent activation of caspase-3/CPP32 protease.

Journal: Cancer letters 20021205

Title: A novel nonpeptidic caspase-3/7 inhibitor, (S)-(+)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin reduces myocardial ischemic injury.

Journal: European journal of pharmacology 20021205

Title: Carbazolequinone induction of caspase-dependent cell death in Src-overexpressing cells.

Journal: Biochemical pharmacology 20021201

Title: Vincristine induced apoptosis in acute lymphoblastic leukaemia cells: a mitochondrial controlled pathway regulated by reactive oxygen species?

Journal: International journal of oncology 20021201

Title: Potassium antimonyl tartrate induces caspase- and reactive oxygen species-dependent apoptosis in lymphoid tumoral cells.

Journal: British journal of haematology 20021201

Title: Suppression of apoptosis and clonogenic survival in irradiated human lymphoblasts with different TP53 status.

Journal: Radiation research 20021201

Title: Implication of caspases during maedi-visna virus-induced apoptosis.

Journal: The Journal of general virology 20021201

Title: Death of HT29 adenocarcinoma cells induced by TNF family receptor activation is caspase-independent and displays features of both apoptosis and necrosis.

Journal: Cell death and differentiation 20021201

Title: Cell death in adult neural stem cells.

Journal: Cell death and differentiation 20021201

Title: c-Jun N-terminal kinase pathway mediates Lactacystin-induced cell death in a neuronal differentiated Neuro2a cell line.

Journal: Brain research. Molecular brain research 20021201

Title: Adriamycin-induced cardiomyocyte and endothelial cell apoptosis: in vitro and in vivo studies.

Journal: Journal of molecular and cellular cardiology 20021201

Title: Fermented wheat germ extract inhibits glycolysis/pentose cycle enzymes and induces apoptosis through poly(ADP-ribose) polymerase activation in Jurkat T-cell leukemia tumor cells.

Journal: The Journal of biological chemistry 20021129

Title: Protein kinase C-alpha and ERK1/2 mediate mitochondrial dysfunction, decreases in active Na+ transport, and cisplatin-induced apoptosis in renal cells.

Journal: The Journal of biological chemistry 20021108

Title: Modulation of caspase activation and p27(Kip1) degradation in the p53-induced apoptosis in IW32 erythroleukemia cells.

Journal: Cellular signalling 20021101

Title: Caspase-independent phosphatidylserine exposure during apoptosis of primary T lymphocytes.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20021101

Title: Caspase-independent photoreceptor apoptosis in vivo and differential expression of apoptotic protease activating factor-1 and caspase-3 during retinal development.

Journal: Cell death and differentiation 20021101

Title: Sensitivity of photoreceptor-derived cell line (661W) to baculoviral p35, Z-VAD.FMK, and Fas-associated death domain.

Journal: Investigative ophthalmology & visual science 20021101

Title: Apoptosis induced by Pseudomonas aeruginosa in antigen presenting cells is diminished by genetic modification with CD40 ligand.

Journal: Pediatric research 20021101

Title: The ubiquitin-proteasome pathway in thymocyte apoptosis: caspase-dependent processing of the deubiquitinating enzyme USP7 (HAUSP).

Journal: Molecular immunology 20021101

Title: Human autologous mixed lymphocyte reaction as an in vitro model for autoreactivity to apoptotic antigens.

Journal: Immunology 20021101

Title: Zinc inhibits nuclear factor-kappa B activation and sensitizes prostate cancer cells to cytotoxic agents.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20021101

Title: Antimycin A-induced apoptosis of HL-60 cells.

Journal: Cytometry 20021101

Title: Pathways leading to apoptotic neurodegeneration following trauma to the developing rat brain.

Journal: Neurobiology of disease 20021101

Title: Apoptotic mechanisms in T47D and MCF-7 human breast cancer cells.

Journal: British journal of cancer 20021007

Title: The role of caspases in cryoinjury: caspase inhibition strongly improves the recovery of cryopreserved hematopoietic and other cells.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021001

Title: Caspase activation in hair cells of the mouse utricle exposed to neomycin.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20021001

Title: Caspase-3 is not activated in seizure-induced neuronal necrosis with internucleosomal DNA cleavage.

Journal: Journal of neurochemistry 20021001

Title: Interferon-gamma augments CD95(APO-1/Fas) and pro-caspase-8 expression and sensitizes human vascular endothelial cells to CD95-mediated apoptosis.

Journal: The American journal of pathology 20021001

Title: Regulation of Bcl-2 family molecules and activation of caspase cascade involved in gypenosides-induced apoptosis in human hepatoma cells.

Journal: Cancer letters 20020926

Title: The caspase inhibitor z-VAD is more effective than CD18 adhesion blockade in reducing muscle ischemia-reperfusion injury: implication for clinical trials.

Journal: Blood 20020915

Title: Raloxifene, a mixed estrogen agonist/antagonist, induces apoptosis through cleavage of BAD in TSU-PR1 human cancer cells.

Journal: The Journal of biological chemistry 20020906

Title: An atypical caspase-independent death pathway for an immunogenic cancer cell line.

Journal: Oncogene 20020905

Title: Inhibitor specificity of recombinant and endogenous caspase-9.

Journal: The Biochemical journal 20020901

Title: Trophoblast differentiation modulates the activity of caspases in primary cultures of term human trophoblasts.

Journal: Pediatric research 20020901

Title: Neuronal apoptosis associated with morphine tolerance: evidence for an opioid-induced neurotoxic mechanism.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020901

Title: Xenogeneic human NK cytotoxicity against porcine endothelial cells is perforin/granzyme B dependent and not inhibited by Bcl-2 overexpression.

Journal: Xenotransplantation 20020901

Title: CD20-induced B cell death can bypass mitochondria and caspase activation.

Journal: Leukemia 20020901

Title: Caspase inhibitors induce a switch from apoptotic to proinflammatory signaling in CD95-stimulated T lymphocytes.

Journal: European journal of immunology 20020901

Title: Granzyme B-mediated degradation of T-cell receptor zeta chain.

Journal: Cancer research 20020901

Title: Effects of caspase inhibition on camptothecin-induced apoptosis of HL-60 cells.

Journal: Cytometry 20020901

Title: Cyclopentenone prostaglandins induce caspase activation and apoptosis in dendritic cells by a PPAR-gamma-independent mechanism: regulation by inflammatory and T cell-derived stimuli.

Journal: Experimental hematology 20020901

Title: Similar time-course of interleukin-1 beta production and extracellular-signal-regulated kinase (ERK) activation in permanent focal brain ischemic injury.

Journal: Metabolic brain disease 20020901

Title: Macrophage colony stimulating factor prevents NMDA-induced neuronal death in hippocampal organotypic cultures.

Journal: Journal of neurochemistry 20020901

Title: Erucylphosphocholine-induced apoptosis in glioma cells: involvement of death receptor signalling and caspase activation.

Journal: Journal of neurochemistry 20020901

Title: Induction of apoptosis dependent on caspase activities and growth arrest in HL-60 cells by PGA2.

Journal: Prostaglandins & other lipid mediators 20020901

Title: Therapeutic strategies targeting caspase inhibition following spinal cord injury in rats.

Journal: Experimental neurology 20020901

Title: Importance of FADD signaling in serum deprivation- and hypoxia-induced cardiomyocyte apoptosis.

Journal: The Journal of biological chemistry 20020830

Title: Selective inhibition of dipeptidyl peptidase I, not caspases, prevents the partial processing of procaspase-3 in CD3-activated human CD8(+) T lymphocytes.

Journal: The Journal of biological chemistry 20020830

Title: Retinoids cause apoptosis in pancreatic cancer cells via activation of RAR-gamma and altered expression of Bcl-2/Bax.

Journal: British journal of cancer 20020827

Title: The poststimulation program of CD4 versus CD8 T cells (death versus activation-induced nonresponsiveness).

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020815

Title: The involvement of oxidative stress in tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in HeLa cells.

Journal: Cancer letters 20020808

Title: Celecoxib induces apoptosis by inhibiting 3-phosphoinositide-dependent protein kinase-1 activity in the human colon cancer HT-29 cell line.

Journal: The Journal of biological chemistry 20020802

Title: Adenovirus-mediated expression of p35 prevents hypoxia/reoxygenation injury by reducing reactive oxygen species and caspase activity.

Journal: Cardiovascular research 20020801

Title: Combretastatin-A4 prodrug induces mitotic catastrophe in chronic lymphocytic leukemia cell line independent of caspase activation and poly(ADP-ribose) polymerase cleavage.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020801

Title: Cofactors of mitochondrial enzymes attenuate copper-induced death in vitro and in vivo.

Journal: Annals of neurology 20020801

Title: Influence of gangliosides on the IL-2- and IL-4-dependent cell proliferation.

Journal: Neurochemical research 20020801

Title: The antiangiogenic agent Neovastat (AE-941) induces endothelial cell apoptosis.

Journal: Molecular cancer therapeutics 20020801

Title: PS-341, a novel proteasome inhibitor, induces Bcl-2 phosphorylation and cleavage in association with G2-M phase arrest and apoptosis.

Journal: Molecular cancer therapeutics 20020801

Title: Caspase inhibition by Z-VAD increases the survival of grafted bone marrow cells and improves functional outcome after MCAo in rats.

Journal: Journal of the neurological sciences 20020715

Title: Prevention and induction of autoimmune exocrinopathy is dependent on pathogenic autoantigen cleavage in murine Sjögren's syndrome.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020715

Title: Late activation of apoptotic pathways plays a negligible role in mediating the cytotoxic effects of discodermolide and epothilone B in non-small cell lung cancer cells.

Journal: Cancer research 20020715

Title: A metal chelator, diphenylthiocarbazone, induces apoptosis in acute promyelocytic leukemia (APL) cells mediated by a caspase-dependent pathway without a modulation of retinoic acid signaling pathways.

Journal: Leukemia research 20020701

Title: Constitutive caspase-like machinery executes programmed cell death in plant cells.

Journal: Cell death and differentiation 20020701

Title: Activation of caspases and cleavage of Bid are required for tyrosine and phenylalanine deficiency-induced apoptosis of human A375 melanoma cells.

Journal: Archives of biochemistry and biophysics 20020701

Title: Manumycin inhibits farnesyltransferase and induces apoptosis of drug-resistant interleukin 6-producing myeloma cells.

Journal: British journal of haematology 20020701

Title: The differential contribution of granzyme A and granzyme B in cytotoxic T lymphocyte-mediated apoptosis is determined by the quality of target cells.

Journal: European journal of immunology 20020701

Title: Inhibition of caspase or FADD function blocks proliferation but not MAP kinase-activation and interleukin-2-production during primary stimulation of T cells.

Journal: European journal of immunology 20020701

Title: Toxaphene, but not beryllium, induces human neutrophil chemotaxis and apoptosis via reactive oxygen species (ROS): involvement of caspases and ROS in the degradation of cytoskeletal proteins.

Journal: Clinical immunology (Orlando, Fla.) 20020701

Title: Among substituted 9,10-dihydro-9,10-[1,2]benzenoanthracene-1,4,5,8-tetraones, the lead antitumor triptycene bisquinone TT24 blocks nucleoside transport, induces apoptotic DNA fragmentation and decreases the viability of L1210 leukemic cells in the nanomolar range of daunorubicin in vitro.

Journal: Anti-cancer drugs 20020701

Title: Necrosis has orderly DNA fragmentations.

Journal: Biochemical and biophysical research communications 20020628

Title: Enhanced development of caspase-independent cortical cell death during cold storage in kidneys of non-heart-beating donors.

Journal: Transplantation 20020615

Title: Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells.

Journal: Oncogene 20020606

Title: cIAP-1, but not XIAP, is cleaved by caspases during the apoptosis induced by TGF-beta in fetal rat hepatocytes.

Journal: FEBS letters 20020605

Title: Modes of activation of mitogen-activated protein kinases and their roles in cepharanthine-induced apoptosis in human leukemia cells.

Journal: Cellular signalling 20020601

Title: p53 expression in K562 cells is associated with caspase-mediated cleavage of c-ABL and BCR-ABL protein kinases.

Journal: British journal of haematology 20020601

Title: Inhibition of programmed cell death impairs in vitro vascular-like structure formation and reduces in vivo angiogenesis.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020601

Title: The molecular mechanism in activation-induced cell death of an Ag-reactive B cell clone.

Journal: Clinical and experimental immunology 20020601

Title: The protection of hybridoma cells from apoptosis by caspase inhibition allows culture recovery when exposed to non-inducing conditions.

Journal: Journal of biotechnology 20020523

Title: Activation of platelet caspases by TNF and its consequences for kinetics.

Journal: Cytokine 20020521

Title: Oxidative stress mediates cell surface expression of SS-A/Ro antigen on keratinocytes.

Journal: Free radical biology & medicine 20020515

Title: Induction of microsomal epoxide hydrolase by sulfur amino acid deprivation via the pathway of C-Jun N-terminal kinase and its extracellular exposure during cell death.

Journal: Free radical biology & medicine 20020515

Title: Ubiquitin/proteasome-dependent degradation of D-type cyclins is linked to tumor necrosis factor-induced cell cycle arrest.

Journal: The Journal of biological chemistry 20020510

Title: Caspase inhibition activates HIV in latently infected cells. Role of tumor necrosis factor receptor 1 and CD95.

Journal: The Journal of biological chemistry 20020503

Title: Valproic acid induces apoptosis in human leukemia cells by stimulating both caspase-dependent and -independent apoptotic signaling pathways.

Journal: Leukemia research 20020501

Title: Mechanism of staurosporine-induced apoptosis in murine hepatocytes.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20020501

Title: Critical role of mitochondria, but not caspases, during glucocorticosteroid-induced human eosinophil apoptosis.

Journal: American journal of respiratory cell and molecular biology 20020501

Title: Activation of caspase-like proteases and induction of apoptosis by isopentenyladenosine in tobacco BY-2 cells.

Journal: Planta 20020501

Title: Insulin-like growth factor binding protein-related protein 1 inhibits proliferation of MCF-7 breast cancer cells via a senescence-like mechanism.

Journal: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 20020501

Title: Novel extranuclear-targeted anthracyclines override the antiapoptotic functions of Bcl-2 and target protein kinase C pathways to induce apoptosis.

Journal: Molecular cancer therapeutics 20020501

Title: Signaling and function of caspase and c-jun N-terminal kinase in cisplatin-induced apoptosis.

Journal: Molecules and cells 20020430

Title: Requirement of c-Jun N terminal kinase and P38 mitogen-activated protein kinase for anti-IgM-induced reduction in mitochondrial membrane potential in CH31 B lymphoma cells.

Journal: Immunology letters 20020422

Title: JTE-522-induced apoptosis in human gastric adenocarcinoma [correction of adenocarcinoma] cell line AGS cells by caspase activation accompanying cytochrome C release, membrane translocation of Bax and loss of mitochondrial membrane potential.

Journal: World journal of gastroenterology 20020415

Title: Pathways of proximal tubular cell death in bismuth nephrotoxicity.

Journal: Toxicology and applied pharmacology 20020415

Title: Thrombocytopenia in an animal model of malaria is associated with an increased caspase-mediated death of thrombocytes.

Journal: Apoptosis : an international journal on programmed cell death 20020401

Title: Effects of BAPTA-AM, Forskolin, DSF and Z.VAD.fmk on PDT-induced apoptosis and m-THPC phototoxicity on B16 cells.

Journal: Apoptosis : an international journal on programmed cell death 20020401

Title: Commitment to apoptosis induced by tumour necrosis factor-alpha is dependent on caspase activity.

Journal: Apoptosis : an international journal on programmed cell death 20020401

Title: Caspase activation in retinas of diabetic and galactosemic mice and diabetic patients.

Journal: Diabetes 20020401

Title: Role of caspase-3 activation in cerebral ischemia-induced neurodegeneration in adult and neonatal brain.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020401

Title: Caspase inhibitors attenuate 1-methyl-4-phenylpyridinium toxicity in primary cultures of mesencephalic dopaminergic neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020401

Title: Growth phase-dependent expression of ICAD-L/DFF45 modulates the pattern of apoptosis in human colonic cancer cells.

Journal: Cancer research 20020401

Title: Apoptotic effects of ginsenoside Rh2 on human malignant melanoma A375-S2 cells.

Journal: Acta pharmacologica Sinica 20020401

Title: Induction of cell death in T lymphocytes by invasin via beta1-integrin.

Journal: European journal of immunology 20020401

Title: TRAIL enhances thymidine kinase/ganciclovir gene therapy of neuroblastoma cells.

Journal: Cancer gene therapy 20020401

Title: Downregulation of IL-6-induced STAT3 tyrosine phosphorylation by TGF-beta1 is mediated by caspase-dependent and -independent processes.

Journal: Leukemia 20020401

Title: Matrix protein mutations contribute to inefficient induction of apoptosis leading to persistent infection of human neural cells by vesicular stomatitis virus.

Journal: Virology 20020330

Title: Bcl-X(L) and calyculin A prevent translocation of Bax to mitochondria during apoptosis.

Journal: Biochemical and biophysical research communications 20020315

Title: Anticarcinogenic effect of FTY720 in human prostate carcinoma DU145 cells: modulation of mitogenic signaling, FAK, cell-cycle entry and apoptosis.

Journal: International journal of cancer 20020310

Title: A cellular mechanism that reversibly inactivates pancaspase inhibitor zAsp-CH(2)-DCB: a potential pitfall causing discrepancy between in vitro and in vivo caspase assays.

Journal: Biochemical and biophysical research communications 20020308

Title: Ligands of peroxisome proliferator-activated receptor-gamma induce apoptosis in AR42J cells.

Journal: Pancreas 20020301

Title: The membrane attack complex of complement induces caspase activation and apoptosis.

Journal: European journal of immunology 20020301

Title: 3-Hydroxy-3-methyl-glutaryl coenzyme A reductase inhibitors, atorvastatin and simvastatin, induce apoptosis of vascular smooth muscle cells by downregulation of Bcl-2 expression and Rho A prenylation.

Journal: Atherosclerosis 20020301

Title: Role of Caspase-1 in experimental pneumococcal meningitis: Evidence from pharmacologic Caspase inhibition and Caspase-1-deficient mice.

Journal: Annals of neurology 20020301

Title: Gas1 is induced during and participates in excitotoxic neuronal death.

Journal: Molecular and cellular neurosciences 20020301

Title: 2-Chloroadenosine but not adenosine induces apoptosis in rheumatoid fibroblasts independently of cell surface adenosine receptor signalling.

Journal: British journal of pharmacology 20020301

Title: Cells bearing mutations causing Leber's hereditary optic neuropathy are sensitized to Fas-Induced apoptosis.

Journal: The Journal of biological chemistry 20020222

Title: Lysosomal proteases as potential targets for the induction of apoptotic cell death in human neuroblastomas.

Journal: International journal of cancer 20020220

Title: P35-sensitive caspases, MAP kinases and Rho modulate beta-adrenergic induction of apoptosis in mollusc immune cells.

Journal: Journal of cell science 20020215

Title: The 3C protease activity of enterovirus 71 induces human neural cell apoptosis.

Journal: Virology 20020215

Title: Mechanisms of Interferon-alpha induced apoptosis in malignant cells.

Journal: Oncogene 20020214

Title: C-Jun N-terminal kinase is required for phorbol ester- and thapsigargin-induced apoptosis in the androgen responsive prostate cancer cell line LNCaP.

Journal: Oncogene 20020207

Title: Galectin-7 (PIG1) exhibits pro-apoptotic function through JNK activation and mitochondrial cytochrome c release.

Journal: The Journal of biological chemistry 20020201

Title: Activation of chymotrypsin-like serine protease(s) during apoptosis detected by affinity-labeling of the enzymatic center with fluoresceinated inhibitor.

Journal: International journal of oncology 20020201

Title: Paclitaxel triggers cell death primarily via caspase-independent routes in the non-small cell lung cancer cell line NCI-H460.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020201

Title: Rapid caspase-dependent cell death in cultured human breast cancer cells induced by the polyamine analogue N(1),N(11)-diethylnorspermine.

Journal: European journal of biochemistry 20020201

Title: Butyrate induces apoptosis in murine macrophages via caspase-3, but independent of autocrine synthesis of tumor necrosis factor and nitric oxide.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20020201

Title: p38 MAP kinase mediates the cell death induced by PrP106-126 in the SH-SY5Y neuroblastoma cells.

Journal: Neurobiology of disease 20020201

Title: Modulation of apoptosis by mitochondrial uncouplers: apoptosis-delaying features despite intrinsic cytotoxicity.

Journal: Biochemical pharmacology 20020201

Title: Induction of apoptosis by 3,4'-dimethoxy-5-hydroxystilbene in human promyeloid leukemic HL-60 cells.

Journal: Planta medica 20020201

Title: Menadione-induced apoptosis: roles of cytosolic Ca(2+) elevations and the mitochondrial permeability transition pore.

Journal: Journal of cell science 20020201

Title: The omega-hydroxy palmitic acid induced apoptosis in human lung carcinoma cell lines H596 and A549.

Journal: Journal of biochemistry, molecular biology, and biophysics : JBMBB : the official journal of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) 20020201

Title: Akt protein kinase inhibits non-apoptotic programmed cell death induced by ceramide.

Journal: The Journal of biological chemistry 20020125

Title: Multiple pathways of TWEAK-induced cell death.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020115

Title: Granulocyte colony-stimulating factor inhibits the mitochondria-dependent activation of caspase-3 in neutrophils.

Journal: Blood 20020115

Title: Productive HIV-1 infection of primary CD4+ T cells induces mitochondrial membrane permeabilization leading to a caspase-independent cell death.

Journal: The Journal of biological chemistry 20020111

Title: Apoptosis induced by low-dose paclitaxel is associated with p53 upregulation in nasopharyngeal carcinoma cells.

Journal: International journal of cancer 20020110

Title: Ceramide does not act as a general second messenger for ultraviolet-induced apoptosis.

Journal: Oncogene 20020103

Title: Mitochondrial dysfunction is an essential step for killing of non-small cell lung carcinomas resistant to conventional treatment.

Journal: Oncogene 20020103

Title: A study on permeability transition pore opening and cytochrome c release from mitochondria, induced by caspase-3 in vitro.

Journal: FEBS letters 20020102

Title: The prevention of the staurosporine-induced apoptosis by Bcl-X(L), but not by Bcl-2 or caspase inhibitors, allows the extensive differentiation of human neuroblastoma cells.

Journal: Journal of neurochemistry 20020101

Title: Anti-CD20 antibody (IDEC-C2B8, rituximab) enhances efficacy of cytotoxic drugs on neoplastic lymphocytes in vitro: role of cytokines, complement, and caspases.

Journal: Haematologica 20020101

Title: Ajoene, an experimental anti-leukemic drug: mechanism of cell death.

Journal: Leukemia 20020101

Title: Release of annexin V-binding membrane microparticles from cultured human umbilical vein endothelial cells after treatment with camptothecin.

Journal: BMC cell biology 20020101

Title: Higher pH promotes megakaryocytic maturation and apoptosis.

Journal: Stem cells (Dayton, Ohio) 20020101

Title: Hydrogen peroxide-induced apoptosis: oxidative or reductive stress?

Journal: Methods in enzymology 20020101

Title: The antibacterial drug taurolidine induces apoptosis by a mitochondrial cytochrome c-dependent mechanism.

Journal: Anticancer research 20020101

Title: Sequential activation of caspases and serine proteases (serpases) during apoptosis.

Journal: Cell cycle (Georgetown, Tex.) 20020101

Title: A novel caspase dependent pathway is involved in apoptosis of human endothelial cells by Shiga toxins.

Journal: Microbiology and immunology 20020101

Title: Differential modulation of interleukin-2-and interleukin-4-mediated early activation of normal human B lymphocytes by the caspase inhibitor zVAD-fmk.

Journal: European cytokine network 20020101

Title: Detection of rubella-virus-induced apoptosis in Vero cell cultures with hematoxylin and eosin staining.

Journal: Revista Argentina de microbiologia 20020101

Title: Activation of caspase-8 in 3-deazaadenosine-induced apoptosis of U-937 cells occurs downstream of caspase-3 and caspase-9 without Fas receptor-ligand interaction.

Journal: Experimental & molecular medicine 20011231

Title: NF-kappa B activation mediates doxorubicin-induced cell death in N-type neuroblastoma cells.

Journal: The Journal of biological chemistry 20011228

Title: Rotenone-induced G2/M cell cycle arrest and apoptosis in a human B lymphoma cell line PW.

Journal: Biochemical and biophysical research communications 20011221

Title: Role of caspases in human renal proximal tubular epithelial cell apoptosis.

Journal: European journal of pharmacology 20011221

Title: p53-independent induction of apoptosis by the HTLV-I tax protein following UV irradiation.

Journal: Virology 20011220

Title: Hepatocyte growth factor/scatter factor blocks the mitochondrial pathway of apoptosis signaling in breast cancer cells.

Journal: The Journal of biological chemistry 20011214

Title: Regulation of caspases and XIAP in the brain after asphyxial cardiac arrest in rats.

Journal: Neuroreport 20011204

Title: Mechanism of apoptosis induced by zinc deficiency in peripheral blood T lymphocytes.

Journal: Apoptosis : an international journal on programmed cell death 20011201

Title: Glucocorticoid-induced plasma membrane depolarization during thymocyte apoptosis: association with cell shrinkage and degradation of the Na(+)/K(+)-adenosine triphosphatase.

Journal: Endocrinology 20011201

Title: 15-deoxy-delta12,14-prostaglandin J2-induced apoptosis in amnion-like WISH cells.

Journal: Prostaglandins & other lipid mediators 20011201

Title: Generation of reactive oxygen species is not involved in idarubicin-induced apoptosis in human leukaemic cells.

Journal: British journal of haematology 20011201

Title: Activation of apoptosis pathways in peripheral blood lymphocytes by in vivo chemotherapy.

Journal: Blood 20011115

Title: Cellular damage signals promote sequential changes at the N-terminus and BH-1 domain of the pro-apoptotic protein Bak.

Journal: Oncogene 20011115

Title: Apoptosis by pan-caspase inhibitors in lipopolysaccharide-activated macrophages.

Journal: American journal of physiology. Lung cellular and molecular physiology 20011101

Title: A multistep model for paclitaxel-induced apoptosis in human breast cancer cell lines.

Journal: Experimental cell research 20011101

Title: Cladribine induces apoptosis in human leukaemia cells by caspase-dependent and -independent pathways acting on mitochondria.

Journal: The Biochemical journal 20011101

Title: The role of caspases in methotrexate-induced gastrointestinal toxicity.

Journal: Surgery 20011101

Title: Involvement of caspases and of mitochondria in Fas ligation-induced eosinophil apoptosis: modulation by interleukin-5 and interferon-gamma.

Journal: Journal of leukocyte biology 20011101

Title: Activation of extracellular signal-regulated kinases potentiates hemin toxicity in astrocyte cultures.

Journal: Journal of neurochemistry 20011101

Title: Secondary necrosis is a source of proteolytically modified forms of specific intracellular autoantigens: implications for systemic autoimmunity.

Journal: Arthritis and rheumatism 20011101

Title: Blocking caspase-3-mediated proteolysis of IKKbeta suppresses TNF-alpha-induced apoptosis.

Journal: Molecular cell 20011101

Title: Dlk/ZIP kinase-induced apoptosis in human medulloblastoma cells: requirement of the mitochondrial apoptosis pathway.

Journal: British journal of cancer 20011101

Title: Ethanol impairs insulin-stimulated mitochondrial function in cerebellar granule neurons.

Journal: Cellular and molecular life sciences : CMLS 20011101

Title: Human chondrocyte apoptosis in response to mechanical injury.

Journal: Osteoarthritis and cartilage 20011101

Title: beta(2)-microglobulin induces apoptosis in HL-60 human leukemia cell line and its multidrug resistant variants overexpressing MRP1 but lacking Bax or overexpressing P-glycoprotein.

Journal: Oncogene 20011025

Title: Kainate excitotoxicity in organotypic hippocampal slice cultures: evidence for multiple apoptotic pathways.

Journal: Brain research 20011019

Title: Apoptosis is associated with modifications of bcl-2 mRNA AU-binding proteins.

Journal: Biochemical and biophysical research communications 20011012

Title: Inhibition of ceramide production reverses TNF-induced insulin resistance.

Journal: Biochemical and biophysical research communications 20011012

Title: Differential involvement of initiator caspases in apoptotic volume decrease and potassium efflux during Fas- and UV-induced cell death.

Journal: The Journal of biological chemistry 20011005

Title: Inhibition of NFkappaB induces caspase-independent cell death in human T lymphocytes.

Journal: Biochemical and biophysical research communications 20011005

Title: Cyclopentenyl cytosine induces apoptosis and increases cytarabine-induced apoptosis in a T-lymphoblastic leukemic cell-line.

Journal: Leukemia research 20011001

Title: Mechanism of apoptosis in HL-60 cells induced by n-3 and n-6 polyunsaturated fatty acids.

Journal: Biochemical pharmacology 20011001

Title: NSAIDs induce both necrosis and apoptosis in guinea pig gastric mucosal cells in primary culture.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20011001

Title: Stathmo-apoptosis: arresting apoptosis by fluorochrome-labeled inhibitor of caspases.

Journal: International journal of oncology 20011001

Title: Interleukin-5 inhibits translocation of Bax to the mitochondria, cytochrome c release, and activation of caspases in human eosinophils.

Journal: Blood 20011001

Title: Ethanol-induced apoptosis in hepatoma cells proceeds via intracellular Ca(2+) elevation, activation of TLCK-sensitive proteases, and cytochrome c release.

Journal: Experimental cell research 20011001

Title: Investigation of a potential scintigraphic marker of apoptosis: radioiodinated Z-Val-Ala-DL-Asp(O-methyl)-fluoromethyl ketone.

Journal: Nuclear medicine and biology 20011001

Title: Caspase inhibition supports proper gene expression in ex vivo mouse limb cultures.

Journal: Cell death and differentiation 20011001

Title: Intracellular water motion decreases in apoptotic macrophages after caspase activation.

Journal: Cell death and differentiation 20011001

Title: Caspase-dependent and serine protease-dependent DNA fragmentation of myocytes in the ischemia-reperfused rabbit heart: these inhibitors do not reduce infarct size.

Journal: Japanese circulation journal 20011001

Title: Immune-mediated phagocytosis and killing of Streptococcus pneumoniae are associated with direct and bystander macrophage apoptosis.

Journal: The Journal of infectious diseases 20010915

Title: Targeting of the transcription factor Max during apoptosis: phosphorylation-regulated cleavage by caspase-5 at an unusual glutamic acid residue in position P1.

Journal: The Biochemical journal 20010915

Title: Curcumin inhibits activation of Vgamma9Vdelta2 T cells by phosphoantigens and induces apoptosis involving apoptosis-inducing factor and large scale DNA fragmentation.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010915

Title: Modulation of tumor necrosis factor apoptosis-inducing ligand- induced NF-kappa B activation by inhibition of apical caspases.

Journal: The Journal of biological chemistry 20010914

Title: c-IAP1 blocks TNFalpha-mediated cytotoxicity upstream of caspase-dependent and -independent mitochondrial events in human leukemic cells.

Journal: Biochemical and biophysical research communications 20010914

Title: Bax-dependent apoptosis induced by ceramide in HL-60 cells.

Journal: FEBS letters 20010914

Title: Caspase-dependent cleavage of ErbB-2 by geldanamycin and staurosporin.

Journal: The Journal of biological chemistry 20010907

Title: Involvement of transcriptional repressor ATF3 in acceleration of caspase protease activation during DNA damaging agent-induced apoptosis.

Journal: Journal of cellular physiology 20010901

Title: Cutting edge: amelioration of kidney disease in a transgenic mouse model of lupus nephritis by administration of the caspase inhibitor carbobenzoxy-valyl-alanyl-aspartyl-(beta-o-methyl)-fluoromethylketone.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010901

Title: Proteasome inhibitor-induced apoptosis of B-chronic lymphocytic leukaemia cells involves cytochrome c release and caspase activation, accompanied by formation of an approximately 700 kDa Apaf-1 containing apoptosome complex.

Journal: Leukemia 20010901

Title: Growth factor withdrawal from primary human erythroid progenitors induces apoptosis through a pathway involving glycogen synthase kinase-3 and Bax.

Journal: Blood 20010901

Title: Rapid extracellular release of cytochrome c is specific for apoptosis and marks cell death in vivo.

Journal: Blood 20010901

Title: Bcl-x(S) can form homodimers and heterodimers and its apoptotic activity requires localization of Bcl-x(S) to the mitochondria and its BH3 and loop domains.

Journal: Cell death and differentiation 20010901

Title: TNF-alpha-induced cell death in feline immunodeficiency virus-infected cells is mediated by the caspase cascade.

Journal: Virology 20010901

Title: Differential involvement of caspases in hydroquinone-induced apoptosis in human leukemic hl-60 and jurkat cells.

Journal: Toxicology and applied pharmacology 20010901

Title: Degradation of focal adhesion proteins paxillin and p130cas by caspases or calpains in apoptotic rat-1 and L929 cells.

Journal: Biochemical and biophysical research communications 20010824

Title: An IkappaBalpha inhibitor causes leukemia cell death through a p38 MAP kinase-dependent, NF-kappaB-independent mechanism.

Journal: Cancer research 20010815

Title: 2-Methoxyestradiol induces G2/M arrest and apoptosis in prostate cancer.

Journal: Biochemical and biophysical research communications 20010803

Title: Mac-1 (CD11b/CD18) and intercellular adhesion molecule-1 in ischemia-reperfusion injury of rat liver.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20010801

Title: Apoptosis induction and cell cycle perturbation in established cell lines by peroxysomicine A1 (T-514).

Journal: Drug and chemical toxicology 20010801

Title: Oxidative damage to mitochondria is a preliminary step to caspase-3 activation in fluoride-induced apoptosis in HL-60 cells.

Journal: Free radical biology & medicine 20010801

Title: A role of the mitochondrial apoptosis-inducing factor in granulysin-induced apoptosis.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010801

Title: Methionine aminopeptidase-2 regulates human mesothelioma cell survival: role of Bcl-2 expression and telomerase activity.

Journal: The American journal of pathology 20010801

Title: Nitric oxide mediates dendritic cell apoptosis by downregulating inhibitors of apoptosis proteins and upregulating effector caspase activity.

Journal: Surgery 20010801

Title: Partial resistance to malonate-induced striatal cell death in transgenic mouse models of Huntington's disease is dependent on age and CAG repeat length.

Journal: Journal of neurochemistry 20010801

Title: Proteasomal inhibition leads to formation of ubiquitin/alpha-synuclein-immunoreactive inclusions in PC12 cells.

Journal: Journal of neurochemistry 20010801

Title: Different pathways mediate cytochrome c release after photodynamic therapy with hypericin.

Journal: Photochemistry and photobiology 20010801

Title: Temporal relationship between cytochrome c release and mitochondrial swelling during UV-induced apoptosis in living HeLa cells.

Journal: Journal of cell science 20010801

Title: Disruption of focal adhesions mediates detachment during neuronal apoptosis.

Journal: Neuroreport 20010720

Title: The NS2 protein generated by the parvovirus minute virus of mice is degraded by the proteasome in a manner independent of ubiquitin chain elongation or activation.

Journal: Virology 20010705

Title: Early molecular changes in irradiated aortic endothelium.

Journal: Journal of cellular physiology 20010701

Title: Activation of caspase-3 in renal cell carcinoma cells by anthracyclines or 5-fluorouracil.

Journal: International journal of oncology 20010701

Title: Elevated extracellular [K+] inhibits death-receptor- and chemical-mediated apoptosis prior to caspase activation and cytochrome c release.

Journal: The Biochemical journal 20010701

Title: Involvement of FAN in TNF-induced apoptosis.

Journal: The Journal of clinical investigation 20010701

Title: Induction of apoptosis in prostate carcinoma cells by BH3 peptides which inhibit Bak/Bcl-2 interactions.

Journal: British journal of cancer 20010701

Title: Apoptotic signaling in dopamine-induced cell death: the role of oxidative stress, p38 mitogen-activated protein kinase, cytochrome c and caspases.

Journal: Journal of neurochemistry 20010701

Title: Crucial role of calpain in hypoxic PC12 cell death: calpain, but not caspases, mediates degradation of cytoskeletal proteins and protein kinase C-alpha and -delta.

Journal: Neurological research 20010701

Title: The history of Z-VAD-FMK, a tool for understanding the significance of caspase inhibition.

Journal: Acta histochemica 20010701

Title: Methylmercury and H(2)O(2) provoke lysosomal damage in human astrocytoma D384 cells followed by apoptosis.

Journal: Free radical biology & medicine 20010615

Title: Liver-derived DEC205+B220+CD19- dendritic cells regulate T cell responses.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010615

Title: Resveratrol induces extensive apoptosis by depolarizing mitochondrial membranes and activating caspase-9 in acute lymphoblastic leukemia cells.

Journal: Cancer research 20010615

Title: Differential regulation of apoptosis in AK-5 tumor cells by the proto-oncogene Bcl-2: presence of Bcl-2 dependent and independent pathways.

Journal: FEBS letters 20010615

Title: Staurosporine induces apoptosis through both caspase-dependent and caspase-independent mechanisms.

Journal: Oncogene 20010607

Title: p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents.

Journal: Oncogene 20010607

Title: Paclitaxel induces prolonged activation of the Ras/MEK/ERK pathway independently of activating the programmed cell death machinery.

Journal: The Journal of biological chemistry 20010601

Title: Collagen gel overlay induces two phases of apoptosis in MDCK cells.

Journal: American journal of physiology. Cell physiology 20010601

Title: Differential effect of MLC kinase in TNF-alpha-induced endothelial cell apoptosis and barrier dysfunction.

Journal: American journal of physiology. Lung cellular and molecular physiology 20010601

Title: Effect of inhibitors of cysteine and serine proteases in anticancer drug-induced apoptosis in gastric cancer cells.

Journal: International journal of oncology 20010601

Title: Inhibition of p38 kinase reveals a TNF-alpha-mediated, caspase-dependent, apoptotic death pathway in a human myelomonocyte cell line.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010601

Title: Synergistic protective effect of caspase inhibitors and bFGF against brain injury induced by transient focal ischaemia.

Journal: British journal of pharmacology 20010601

Title: The bisphosphonate ibandronate promotes apoptosis in MDA-MB-231 human breast cancer cells in bone metastases.

Journal: Cancer research 20010601

Title: Caspase activity in newt spermatogonial apoptosis induced by prolactin and cycloheximide.

Journal: Molecular reproduction and development 20010601

Title: Caspase inhibition reduces apoptotic death of cryopreserved porcine hepatocytes.

Journal: Hepatology (Baltimore, Md.) 20010601

Title: Quinone isomers of the WS-5995 antibiotics: synthetic antitumor agents that inhibit macromolecule synthesis, block nucleoside transport, induce DNA fragmentation, and decrease the growth and viability of L1210 leukemic cells more effectively than ellagic acid and genistein in vitro.

Journal: Anti-cancer drugs 20010601

Title: Involvement of p38 in apoptosis-associated membrane blebbing and nuclear condensation.

Journal: Molecular biology of the cell 20010601

Title: Treatment with inhibitors of caspases, that are substrates of drug transporters, selectively permits chemotherapy-induced apoptosis in multidrug-resistant cells but protects normal cells.

Journal: Leukemia 20010601

Title: Spontaneous in contrast to CD95-induced neutrophil apoptosis is independent of caspase activity.

Journal: The Journal of trauma 20010601

Title: Amyloid beta peptide-induced cerebral endothelial cell death involves mitochondrial dysfunction and caspase activation.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20010601

Title: C2-ceramide signaling in glioma cells: synergistic enhancement of CD95-mediated, caspase-dependent apoptosis.

Journal: Cell death and differentiation 20010601

Title: Ionizing radiation modulates vascular endothelial growth factor (VEGF) expression through multiple mitogen activated protein kinase dependent pathways.

Journal: Oncogene 20010531

Title: Trail-induced apoptosis in Type I leukemic cells is not enhanced by overexpression of bax.

Journal: Biochemical and biophysical research communications 20010525

Title: Sequential two-step cleavage of the retinoblastoma protein by caspase-3/-7 during etoposide-induced apoptosis.

Journal: Oncogene 20010524

Title: Beta -amyloid-(1-42) impairs activity-dependent cAMP-response element-binding protein signaling in neurons at concentrations in which cell survival Is not compromised.

Journal: The Journal of biological chemistry 20010518

Title: Exploitation of a non-apoptotic caspase to regulate the abundance of the cdkI p27(KIP1) in transformed lymphoid cells.

Journal: Oncogene 20010517

Title: Ganglioside G(D2) in small cell lung cancer cell lines: enhancement of cell proliferation and mediation of apoptosis.

Journal: Cancer research 20010515

Title: MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors.

Journal: The Journal of biological chemistry 20010511

Title: Febrile and acute hyperthermia enhance TNF-induced necrosis of murine L929 fibrosarcoma cells via caspase-regulated production of reactive oxygen intermediates.

Journal: Journal of cellular physiology 20010501

Title: Detection of caspases activation by fluorochrome-labeled inhibitors: Multiparameter analysis by laser scanning cytometry.

Journal: Cytometry 20010501

Title: Possible involvement of EBV-mediated alpha-fodrin cleavage for organ-specific autoantigen in Sjogren's syndrome.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010501

Title: Antibodies against c-Jun N-terminal peptide cross-react with neo-epitopes emerging after caspase-mediated proteolysis during apoptosis.

Journal: Journal of neurochemistry 20010501

Title: The incidence of cytoplasmic fragmentation in mouse embryos in vitro is not affected by inhibition of caspase activity.

Journal: Fertility and sterility 20010501

Title: Granulocyte colony-stimulating factor inhibits Fas-triggered apoptosis in bone marrow cells isolated from patients with refractory anemia with ringed sideroblasts.

Journal: Leukemia 20010501

Title: Overexpressed human RAD50 exhibits cell death in a p21(WAF1/CIP1)-dependent manner: its potential utility in local gene therapy of tumor.

Journal: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 20010501

Title: Sodium nitroprusside induces apoptosis of H9C2 cardiac muscle cells in a c-Jun N-terminal kinase-dependent manner.

Journal: International immunopharmacology 20010501

Title: Elevated vulnerability to oxidative stress-induced cell death and activation of caspase-3 by the Swedish amyloid precursor protein mutation.

Journal: Journal of neuroscience research 20010415

Title: The C-class chemokine lymphotactin costimulates the apoptosis of human CD4(+) T cells.

Journal: Blood 20010415

Title: Endoplasmic reticulum localized Bcl-2 prevents apoptosis when redistribution of cytochrome c is a late event.

Journal: Oncogene 20010412

Title: Activation of the Fas pathway independently of Fas ligand during apoptosis induced by camptothecin in p53 mutant human colon carcinoma cells.

Journal: Oncogene 20010405

Title: Differential effects of caspase inhibitors on endotoxin-induced myocardial dysfunction and heart apoptosis.

Journal: American journal of physiology. Heart and circulatory physiology 20010401

Title: E-cadherin-mediated cell contact prevents apoptosis of spontaneously immortalized granulosa cells by regulating Akt kinase activity.

Journal: Biology of reproduction 20010401

Title: Potentiation of okadaic acid-induced ceramide elevation but not apoptosis by inhibition of glucosylceramide synthase in human neuroepithelioma cells.

Journal: Biochemical pharmacology 20010401

Title: Rescue from death but not from functional impairment: caspase inhibition protects dopaminergic cells against 6-hydroxydopamine-induced apoptosis but not against the loss of their terminals.

Journal: Journal of neurochemistry 20010401

Title: Se-methylselenocysteine induces apoptosis through caspase activation in HL-60 cells.

Journal: Carcinogenesis 20010401

Title: Myristoleic acid, a cytotoxic component in the extract from Serenoa repens, induces apoptosis and necrosis in human prostatic LNCaP cells.

Journal: The Prostate 20010401

Title: Herpes simplex virus thymidine kinase/ganciclovir-induced cell death is enhanced by co-expression of caspase-3 in ovarian carcinoma cells.

Journal: Cancer gene therapy 20010401

Title: Role of mitochondria and caspases in vitamin D-mediated apoptosis of MCF-7 breast cancer cells.

Journal: The Journal of biological chemistry 20010323

Title: Involvement of caspases in 4-hydroxy-alkenal-induced apoptosis in human leukemic cells.

Journal: Free radical biology & medicine 20010315

Title: IL-7 prevents both caspase-dependent and -independent pathways that lead to the spontaneous apoptosis of i-IEL.

Journal: Cellular immunology 20010315

Title: Immunohistochemical investigation of caspase-1 and effect of caspase-1 inhibitor in delayed neuronal death after transient cerebral ischemia.

Journal: Brain research 20010302

Title: Inhibition of caspase 3 abrogates lipopolysaccharide-induced nitric oxide production by preventing activation of NF-kappaB and c-Jun NH2-terminal kinase/stress-activated protein kinase in RAW 264.7 murine macrophage cells.

Journal: Infection and immunity 20010301

Title: Proteasomes modulate balance among proapoptotic and antiapoptotic Bcl-2 family members and compromise functioning of the electron transport chain in leukemic cells.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010301

Title: Nerve growth factor prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced cell death via the Akt pathway by suppressing caspase-3-like activity using PC12 cells: relevance to therapeutical application for Parkinson's disease.

Journal: Journal of neuroscience research 20010301

Title: Low concentrations of 1-methyl-4-phenylpyridinium ion induce caspase-mediated apoptosis in human SH-SY5Y neuroblastoma cells.

Journal: Journal of neuroscience research 20010301

Title: Calcium ionophore A23187 specifically decreases the secretion of beta-secretase cleaved amyloid precursor protein during apoptosis in primary rat cortical cultures.

Journal: Journal of neuroscience research 20010301

Title: Signal transduction activated by the cancer chemopreventive isothiocyanates: cleavage of BID protein, tyrosine phosphorylation and activation of JNK.

Journal: British journal of cancer 20010301

Title: Ceramide-induced cell death in the prostate cancer cell line LNCaP has both necrotic and apoptotic features.

Journal: The Prostate 20010301

Title: High-efficiency electrotransfection of human primary hematopoietic stem cells.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010301

Title: Pro-apoptotic function of calsenilin/DREAM/KChIP3.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010301

Title: Caspase-mediated cleavage of TRAF3 in FasL-stimulated Jurkat-T cells.

Journal: Journal of leukocyte biology 20010301

Title: Caspase-dependent cleavage of cadherins and catenins during osteoblast apoptosis.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010301

Title: Purpurin-18 in combination with light leads to apoptosis or necrosis in HL60 leukemia cells.

Journal: Photochemistry and photobiology 20010301

Title: Complement activation by apoptotic endothelial cells following hypoxia/reoxygenation.

Journal: Immunology 20010301

Title: Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis.

Journal: Oncogene 20010301

Title: Caspase-dependent chemotherapy-induced death of glioma cells requires mitochondrial cytochrome c release.

Journal: Biochemical and biophysical research communications 20010223

Title: Vibrio parahaemolyticus thermostable direct hemolysin can induce an apoptotic cell death in Rat-1 cells from inside and outside of the cells.

Journal: FEMS microbiology letters 20010220

Title: Cytoprotection by Jun kinase during nitric oxide-induced cardiac myocyte apoptosis.

Journal: Circulation research 20010216

Title: Resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression.

Journal: Cancer research 20010215

Title: Anoikis and metastatic potential of cloudman S91 melanoma cells.

Journal: Cancer research 20010215

Title: PECAM-1 shedding during apoptosis generates a membrane-anchored truncated molecule with unique signaling characteristics.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010201

Title: Attenuation of bleomycin-induced pneumopathy in mice by a caspase inhibitor.

Journal: American journal of physiology. Lung cellular and molecular physiology 20010201

Title: Protein tyrosine phosphatase-dependent proteolysis of focal adhesion complexes in endothelial cell apoptosis.

Journal: American journal of physiology. Lung cellular and molecular physiology 20010201

Title: PTEN induces apoptosis and cell cycle arrest through phosphoinositol-3-kinase/Akt-dependent and -independent pathways.

Journal: Human molecular genetics 20010201

Title: Prevention of anti-IgM-induced apoptosis accompanying G1 arrest in B lymphoma cells overexpressing dominant-negative mutant form of c-Jun N-terminal kinase 1.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010201

Title: Involvement of caspases in apoptotic cell death of murine macrophages infected with Actinobacillus actinomycetemcomitans.

Journal: Journal of periodontal research 20010201

Title: Stromal derived factor-1 alpha (SDF-1 alpha) induces CD4+ T cell apoptosis via the functional up-regulation of the Fas (CD95)/Fas ligand (CD95L) pathway.

Journal: Journal of leukocyte biology 20010201

Title: Zinc-mediated regulation of caspases activity: dose-dependent inhibition or activation of caspase-3 in the human Burkitt lymphoma B cells (Ramos).

Journal: Cell death and differentiation 20010201

Title: Cleavage of mitogen-activated protein kinases in human neutrophils undergoing apoptosis: role in decreased responsiveness to inflammatory cytokines.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010115

Title: Arsenic trioxide induces apoptosis in human gastric cancer cells through up-regulation of p53 and activation of caspase-3.

Journal: International journal of cancer 20010115

Title: Irradiation of mitochondria initiates apoptosis in a cell free system.

Journal: Oncogene 20010111

Title: Rate-limiting step preceding cytochrome c release in cells primed for Fas-mediated apoptosis revealed by analysis of cellular mosaicism of respiratory changes.

Journal: The Journal of biological chemistry 20010105

Title: Autocrine expression of activated transforming growth factor-beta(1) induces apoptosis in normal rat liver.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20010101

Title: B cell receptor-stimulated mitochondrial phospholipase A2 activation and resultant disruption of mitochondrial membrane potential correlate with the induction of apoptosis in WEHI-231 B cells.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010101

Title: Differential regulation of cell cycle-related proteins by CD95 engagement in thymocytes and T cell leukemic cell line, Jurkat.

Journal: Journal of cellular biochemistry 20010101

Title: Caspase inhibition prevents cardiac dysfunction and heart apoptosis in a rat model of sepsis.

Journal: American journal of respiratory and critical care medicine 20010101

Title: Hierarchical cleavage of focal adhesion kinase by caspases alters signal transduction during apoptosis of intestinal epithelial cells.

Journal: Gastroenterology 20010101

Title: Killing tumour cells by alkylphosphocholines: evidence for involvement of CD95.

Journal: European journal of cell biology 20010101

Title: Radiation sensitivity and apoptosis in human lymphoma cells.

Journal: International journal of radiation biology 20010101

Title: Ceramide generation occurring during 7beta-hydroxycholesterol- and 7-ketocholesterol-induced apoptosis is caspase independent and is not required to trigger cell death.

Journal: Cell death and differentiation 20010101

Title: Caspase-3 activity and carbonyl cyanide m-chlorophenylhydrazone-induced apoptosis in HL-60.

Journal: Alternatives to laboratory animals : ATLA 20010101

Title: Calcium flux measurements in apoptosis.

Journal: Methods in cell biology 20010101

Title: Granulysin blocks replication of varicella-zoster virus and triggers apoptosis of infected cells.

Journal: Viral immunology 20010101

Title: Apoptosis in caspase-inhibited neurons.

Journal: Molecular medicine (Cambridge, Mass.) 20010101

Title: Irofulven (6-hydroxymethylacylfulvene, MGI 114) induces caspase 8 and 9-mediated apoptosis in human pancreatic adenocarcinoma cells.

Journal: Anticancer research 20010101

Title: Cepharanthine activates caspases and induces apoptosis in Jurkat and K562 human leukemia cell lines.

Journal: Journal of cellular biochemistry 20010101

Title: Pan-caspase inhibitor zVAD enhances cell death in RAW246.7 macrophages.

Journal: Journal of endotoxin research 20010101

Title: Caspase inhibition and N6-benzyladenosine-induced apoptosis in HL-60 cells.

Journal: Journal of cellular biochemistry 20010101

Title: Caspase inhibitors block MHV-3 induced apoptosis and enhance viral replication and pathogenicity.

Journal: Advances in experimental medicine and biology 20010101

Title: Antileukemic activity of synthetic daunomycinone derivatives bearing modifications in the glycosidic moiety.

Journal: Anticancer research 20010101

Title: Apoptosis induced by cadmium in human lymphoma U937 cells through Ca2+-calpain and caspase-mitochondria- dependent pathways.

Journal: The Journal of biological chemistry 20001215

Title: Requirement for ERK activation in cisplatin-induced apoptosis.

Journal: The Journal of biological chemistry 20001215

Title: Filamin (280-kDa actin-binding protein) is a caspase substrate and is also cleaved directly by the cytotoxic T lymphocyte protease granzyme B during apoptosis.

Journal: The Journal of biological chemistry 20001215

Title: Overexpression of bcl-2 enhances LIGHT- and interferon-gamma -mediated apoptosis in Hep3BT2 cells.

Journal: The Journal of biological chemistry 20001208

Title: Structure/Function analysis of p55 tumor necrosis factor receptor and fas-associated death domain. Effect on necrosis in L929sA cells.

Journal: The Journal of biological chemistry 20001201

Title: TNF-related apoptosis-inducing ligand-induced apoptosis of melanoma is associated with changes in mitochondrial membrane potential and perinuclear clustering of mitochondria.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20001115

Title: An early oxygen-dependent step is required for dexamethasone-induced apoptosis of immature mouse thymocytes.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20001101

Title: Distinct p300-responsive mechanisms promote caspase-dependent apoptosis by human T-cell lymphotropic virus type 1 Tax protein.

Journal: Molecular and cellular biology 20001101

Title: Activation of caspase-3 and c-Jun NH2-terminal kinase-1 signaling pathways in tamoxifen-induced apoptosis of human breast cancer cells.

Journal: Cancer research 20001101

Title: Bisphosphonates induce breast cancer cell death in vitro.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20001101

Title: Aspirin induces apoptosis through release of cytochrome c from mitochondria.

Journal: Neoplasia (New York, N.Y.) 20001101

Title: Distinct pathways for stimulation of cytochrome c release by etoposide.

Journal: The Journal of biological chemistry 20001020

Title: Bcl-xL inhibits cytochrome c release but not mitochondrial depolarization during the activation of multiple death pathways by tumor necrosis factor-alpha.

Journal: The Journal of biological chemistry 20001006

Title: Mitomycin C induces apoptosis in a caspases-dependent and Fas/CD95-independent manner in human gastric adenocarcinoma cells.

Journal: Cancer letters 20001001

Title: Role of caspases in dexamethasone-induced apoptosis and activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase in human eosinophils.

Journal: Clinical and experimental immunology 20001001

Title: Suicidal differential housekeeping gene activity in apoptosis induced by DCNP.

Journal: Apoptosis : an international journal on programmed cell death 20001001

Title: Effector caspases are dispensable for the early nuclear morphological changes during chemical-induced apoptosis.

Journal: Journal of cell science 20000901

Title: Disulfiram inhibits TNF-alpha-induced cell death.

Journal: Cytokine 20000901

Title: Lack of multicellular drug resistance observed in human ovarian and prostate carcinoma treated with the proteasome inhibitor PS-341.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20000901

Title: Execution of apoptosis signal-regulating kinase 1 (ASK1)-induced apoptosis by the mitochondria-dependent caspase activation.

Journal: The Journal of biological chemistry 20000825

Title: Spermine oxidation leads to necrosis with plasma membrane phosphatidylserine redistribution in mouse leukemia cells.

Journal: Experimental cell research 20000825

Title: Cleavage of the actin-capping protein alpha -adducin at Asp-Asp-Ser-Asp633-Ala by caspase-3 is preceded by its phosphorylation on serine 726 in cisplatin-induced apoptosis of renal epithelial cells.

Journal: The Journal of biological chemistry 20000818

Title: Mechanisms to prevent the toxicity of chronic neuroinflammation on forebrain cholinergic neurons.

Journal: European journal of pharmacology 20000818

Title: In vivo myocardial infarct size reduction by a caspase inhibitor administered after the onset of ischemia.

Journal: European journal of pharmacology 20000818

Title: Caspase-dependent and -independent mechanisms in apoptosis induced by hydroquinone and catechol metabolites of remoxipride in HL-60 cells.

Journal: Chemico-biological interactions 20000815

Title: Sensitization to death receptor cytotoxicity by inhibition of fas-associated death domain protein (FADD)/caspase signaling. Requirement of cell cycle progression.

Journal: The Journal of biological chemistry 20000811

Title: Molecular mechanisms of butylated hydroxylanisole-induced toxicity: induction of apoptosis through direct release of cytochrome c.

Journal: Molecular pharmacology 20000801

Title: Detection of caspase-activation in intact lymphoid cells using standard caspase substrates and inhibitors.

Journal: Journal of immunological methods 20000731

Title: p38 mitogen-activated protein kinase regulates a novel, caspase-independent pathway for the mitochondrial cytochrome c release in ultraviolet B radiation-induced apoptosis.

Journal: The Journal of biological chemistry 20000714

Title: Abrogation of bleomycin-induced epithelial apoptosis and lung fibrosis by captopril or by a caspase inhibitor.

Journal: American journal of physiology. Lung cellular and molecular physiology 20000701

Title: Studies on the cytotoxic mechanisms of ginkgetin in a human ovarian adenocarcinoma cell line.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20000701

Title: Caspase activation and cytochrome c release during HL-60 cell apoptosis induced by a nitric oxide donor.

Journal: Free radical research 20000601

Title: Synergetic activation of p38 mitogen-activated protein kinase and caspase-3-like proteases for execution of calyculin A-induced apoptosis but not N-methyl-d-aspartate-induced necrosis in mouse cortical neurons.

Journal: Journal of neurochemistry 20000601

Title: Zinc-induced neuronal death in cortical neurons.

Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20000601

Title: Involvement of sphingosine in mitochondria-dependent Fas-induced apoptosis of type II Jurkat T cells.

Journal: The Journal of biological chemistry 20000526

Title: Amiodarone induces apoptosis of human and rat alveolar epithelial cells in vitro.

Journal: American journal of physiology. Lung cellular and molecular physiology 20000501

Title: The involvement of caspases in the CD95(Fas/Apo-1)- but not swelling-induced cellular taurine release from Jurkat T-lymphocytes.

Journal: Pflugers Archiv : European journal of physiology 20000501

Title: Arsenic trioxide and the growth of human T-cell leukemia virus type I infected T-cell lines.

Journal: Leukemia & lymphoma 20000501

Title: Anthracyclines trigger apoptosis of both G0-G1 and cycling peripheral blood lymphocytes and induce massive deletion of mature T and B cells.

Journal: Cancer research 20000401

Title: Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139.

Journal: The Journal of biological chemistry 20000331

Title: Tumor-induced apoptosis of T lymphocytes: elucidation of intracellular apoptotic events.

Journal: Blood 20000315

Title: Comparison of the LDH and MTT assays for quantifying cell death: validity for neuronal apoptosis?

Journal: Journal of neuroscience methods 20000315

Title: p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.

Journal: The Journal of biological chemistry 20000310

Title: Chronic mitochondrial inhibition induces selective motoneuron death in vitro: a new model for amyotrophic lateral sclerosis.

Journal: Journal of neurochemistry 20000301

Title: Nuclear factor-kappaB activation by the photochemotherapeutic agent verteporfin.

Journal: Blood 20000101

Title: The lipid peroxidation product 4-hydroxy-2,3-nonenal increases AP-1-binding activity through caspase activation in neurons.

Journal: Journal of neurochemistry 20000101

Title: Functional role and therapeutic implications of neuronal caspase-1 and -3 in a mouse model of traumatic spinal cord injury.

Journal: Neuroscience 20000101

Title: Antiapoptosis chemicals prolong productive lifetimes of mammalian cells upon Sindbis virus vector infection.

Journal: Biotechnology and bioengineering 19991105

Title: Granzyme B-induced loss of mitochondrial inner membrane potential (Delta Psi m) and cytochrome c release are caspase independent.

Journal: Journal of immunology (Baltimore, Md. : 1950) 19991101

Title: Apoptosis induced by vitamin D compounds in breast cancer cells is inhibited by Bcl-2 but does not involve known caspases or p53.

Journal: Cancer research 19991001

Title: Induction of apoptosis by penta-O-galloyl-beta-D-glucose through activation of caspase-3 in human leukemia HL-60 cells.

Journal: European journal of pharmacology 19990924

Title: Characterization of MPP(+)-induced cell death in a dopaminergic neuronal cell line: role of macromolecule synthesis, cytosolic calcium, caspase, and Bcl-2-related proteins.

Journal: Experimental neurology 19990901

Title: Human papillomavirus type 16 E6-enhanced susceptibility of L929 cells to tumor necrosis factor alpha correlates with increased accumulation of reactive oxygen species.

Journal: The Journal of biological chemistry 19990827

Title: Caspases-3 and -7 are activated in goniothalamin-induced apoptosis in human Jurkat T-cells.

Journal: FEBS letters 19990813

Title: Caspase inhibition in camptothecin-treated U-937 cells is coupled with a shift from apoptosis to transient G1 arrest followed by necrotic cell death.

Journal: Cancer research 19990801

Title: CD95-Mediated murine hepatic apoptosis requires an intact glutathione status.

Journal: Hepatology (Baltimore, Md.) 19990701

Title: Sequential dependent enhancement of caspase activation and apoptosis by flavopiridol on paclitaxel-treated human gastric and breast cancer cells.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 19990701

Title: Ataxia telangiectasia-mutated gene product inhibits DNA damage-induced apoptosis via ceramide synthase.

Journal: The Journal of biological chemistry 19990618

Title: Sequential cleavage of poly(ADP-ribose)polymerase and appearance of a small Bax-immunoreactive protein are blocked by Bcl-X(L) and caspase inhibitors during staurosporine-induced dopaminergic neuronal apoptosis.

Journal: Journal of neurochemistry 19990601

Title: Death signals from the B cell antigen receptor target mitochondria, activating necrotic and apoptotic death cascades in a murine B cell line, WEHI-231.

Journal: International immunology 19990601

Title: Geranylgeranylacetone induces apoptosis in HL-60 cells.

Journal: Cell structure and function 19990601

Title: Annexin V delays apoptosis while exerting an external constraint preventing the release of CD4+ and PrPc+ membrane particles in a human T lymphocyte model.

Journal: Journal of immunology (Baltimore, Md. : 1950) 19990515

Title: Cleavage of RasGAP and phosphorylation of mitogen-activated protein kinase in the course of coxsackievirus B3 replication.

Journal: Journal of virology 19990501

Title: Anticancer drugs induce caspase-8/FLICE activation and apoptosis in the absence of CD95 receptor/ligand interaction.

Journal: Blood 19990501

Title: Glucose uptake and glycolysis reduce hypoxia-induced apoptosis in cultured neonatal rat cardiac myocytes.

Journal: The Journal of biological chemistry 19990430

Title: Sodium salicylate activates caspases and induces apoptosis of myeloid leukemia cell lines.

Journal: Blood 19990401

Title: Caspase-mediated degradation of T-cell receptor zeta-chain.

Journal: Cancer research 19990401

Title: Arsenic trioxide induces apoptosis of myeloid leukemia cells by activation of caspases.

Journal: Medical oncology (Northwood, London, England) 19990401

Title: The activation of the c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signaling pathways protects HeLa cells from apoptosis following photodynamic therapy with hypericin.

Journal: The Journal of biological chemistry 19990326

Title: Caspase-dependent activation of calpain during drug-induced apoptosis.

Journal: The Journal of biological chemistry 19990319

Title: Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation.

Journal: Journal of neurochemistry 19990301

Title: Monocytic cell necrosis is mediated by potassium depletion and caspase-like proteases.

Journal: The American journal of physiology 19990301

Title: Neuroprotection by a caspase inhibitor in acute bacterial meningitis.

Journal: Nature medicine 19990301

Title: Activation of stress-activated protein kinase/c-Jun NH2-terminal kinase and p38 kinase in calphostin C-induced apoptosis requires caspase-3-like proteases but is dispensable for cell death.

Journal: The Journal of biological chemistry 19990226

Title: Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis.

Journal: The Journal of biological chemistry 19990219

Title: Activation of caspase-3-like proteases in apoptosis induced by sphingosine and other long-chain bases in Hep3B hepatoma cells.

Journal: The Biochemical journal 19990215

Title: Caspase-1 is not involved in CD95/Fas-induced apoptosis in Jurkat T cells.

Journal: Experimental cell research 19990201

Title: Nerve growth factor inhibits apoptosis induced by tumor necrosis factor in PC12 cells.

Journal: Journal of neuroscience research 19990201

Title: Induction of apoptosis by hinokitiol, a potent iron chelator, in teratocarcinoma F9 cells is mediated through the activation of caspase-3.

Journal: Cell proliferation 19990201

Title: Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL.

Journal: The Journal of biological chemistry 19990122

Title: Ginsenoside RH-2 induces apoptotic cell death in rat C6 glioma via a reactive oxygen- and caspase-dependent but Bcl-X(L)-independent pathway.

Journal: Life sciences 19990101

Title: The antidepressants imipramine, clomipramine, and citalopram induce apoptosis in human acute myeloid leukemia HL-60 cells via caspase-3 activation.

Journal: Journal of biochemical and molecular toxicology 19990101

Title: Reduction of post-traumatic brain injury and free radical production by inhibition of the caspase-1 cascade.

Journal: Neuroscience 19990101

Title: Inhibition of human caspases by peptide-based and macromolecular inhibitors.

Journal: The Journal of biological chemistry 19981204

Title: Evidence that non-caspase proteases are required for chromatin degradation during apoptosis.

Journal: Cell death and differentiation 19981201

Title: Investigation of glucocorticoid-induced apoptotic pathway: processing of caspase-6 but not caspase-3.

Journal: Cell death and differentiation 19981201

Title: Hypericin-induced photosensitization of HeLa cells leads to apoptosis or necrosis. Involvement of cytochrome c and procaspase-3 activation in the mechanism of apoptosis.

Journal: FEBS letters 19981127

Title: Brefeldin A-mediated apoptosis requires the activation of caspases and is inhibited by Bcl-2.

Journal: Experimental cell research 19981125

Title: Tumor necrosis factor induces ceramide oscillations and negatively controls sphingolipid synthases by caspases in apoptotic Kym-1 cells.

Journal: The Journal of biological chemistry 19981120

Title: Role of superoxide in apoptosis induced by growth factor withdrawal.

Journal: The American journal of physiology 19981101

Title: Paclitaxel-associated multimininucleation is permitted by the inhibition of caspase activation: a potential early step in drug resistance.

Journal: Cancer research 19981015

Title: Cystatin A expression reduces bile salt-induced apoptosis in a rat hepatoma cell line.

Journal: The American journal of physiology 19981001

Title: Caspase-independent cell death induced by anti-CD2 or staurosporine in activated human peripheral T lymphocytes.

Journal: Journal of immunology (Baltimore, Md. : 1950) 19981001

Title: Activation of the CD95 (APO-1/Fas) pathway in drug- and gamma-irradiation-induced apoptosis of brain tumor cells.

Journal: Cell death and differentiation 19981001

Title: Extended therapeutic window for caspase inhibition and synergy with MK-801 in the treatment of cerebral histotoxic hypoxia.

Journal: Cell death and differentiation 19981001

Title: Blocking cytochrome c activity within intact neurons inhibits apoptosis.

Journal: The Journal of cell biology 19980921

Title: Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways.

Journal: The Journal of experimental medicine 19980907

Title: Caspase activation and specific cleavage of substrates after coxsackievirus B3-induced cytopathic effect in HeLa cells.

Journal: Journal of virology 19980901

Title: Aspirin and salicylate induce apoptosis and activation of caspases in B-cell chronic lymphocytic leukemia cells.

Journal: Blood 19980815

Title: Granulysin-induced apoptosis. I. Involvement of at least two distinct pathways.

Journal: Journal of immunology (Baltimore, Md. : 1950) 19980815

Title: Cytotoxic T lymphocyte-assisted suicide. Caspase 3 activation is primarily the result of the direct action of granzyme B.

Journal: The Journal of biological chemistry 19980814

Title: Calcium/calmodulin-dependent protein kinase IV is cleaved by caspase-3 and calpain in SH-SY5Y human neuroblastoma cells undergoing apoptosis.

Journal: The Journal of biological chemistry 19980807

Title: Distinct steps in DNA fragmentation pathway during camptothecin-induced apoptosis involved caspase-, benzyloxycarbonyl- and N-tosyl-L-phenylalanylchloromethyl ketone-sensitive activities.

Journal: Cancer research 19980715

Title: Proteasome activation occurs at an early, premitochondrial step of thymocyte apoptosis.

Journal: Journal of immunology (Baltimore, Md. : 1950) 19980701

Title: A comparison of signaling requirements for apoptosis of human B lymphocytes induced by the B cell receptor and CD95/Fas.

Journal: Journal of immunology (Baltimore, Md. : 1950) 19980701

Title: Neurotrophic factors prevent ceramide-induced apoptosis downstream of c-Jun N-terminal kinase activation in PC12 cells.

Journal: Journal of neurochemistry 19980701

Title: Caspases (interleukin-1beta-converting enzyme family proteases) are involved in the regulation of the survival of osteoclasts.

Journal: Bone 19980701

Title: Neuronal death in cultured murine cortical cells is induced by inhibition of GAPDH and triosephosphate isomerase.

Journal: Neurobiology of disease 19980701

Title: Induction of apoptosis by SB202190 through inhibition of p38beta mitogen-activated protein kinase.

Journal: The Journal of biological chemistry 19980626

Title: Inhibition of CPP32-like proteases rescues axotomized retinal ganglion cells from secondary cell death in vivo.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 19980615

Title: Transmissible gastroenteritis coronavirus induces programmed cell death in infected cells through a caspase-dependent pathway.

Journal: Journal of virology 19980601

Title: Proteasome activities decrease during dexamethasone-induced apoptosis of thymocytes.

Journal: The Biochemical journal 19980601

Title: Caspases mediate 6-hydroxydopamine-induced apoptosis but not necrosis in PC12 cells.

Journal: Journal of neurochemistry 19980601

Title: Inhibitors of interleukin-1 beta-converting enzyme-family proteases (caspases) prevent apoptosis without affecting decreased cellular ability to reduce 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide in cerebellar granule neurons.

Journal: Brain research 19980518

Title: Nitric oxide-dependent production of cGMP supports the survival of rat embryonic motor neurons cultured with brain-derived neurotrophic factor.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 19980515

Title: The intracellular domain of p55 tumor necrosis factor receptor induces apoptosis which requires different caspases in naive and neuronal PC12 cells.

Journal: Journal of neuroscience research 19980515

Title: Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver.

Journal: The Journal of biological chemistry 19980501

Title: Activation of caspase 3 (CPP32)-like proteases is essential for TNF-alpha-induced hepatic parenchymal cell apoptosis and neutrophil-mediated necrosis in a murine endotoxin shock model.

Journal: Journal of immunology (Baltimore, Md. : 1950) 19980401

Title: Defects in the ubiquitin pathway induce caspase-independent apoptosis blocked by Bcl-2.

Journal: The Journal of biological chemistry 19980313

Title: Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 19980301

Title: The adenomatous polyposis coli protein and retinoblastoma protein are cleaved early in apoptosis and are potential substrates for caspases.

Journal: Cell death and differentiation 19980301

Title: Distinct cleavage products of nuclear proteins in apoptosis and necrosis revealed by autoantibody probes.

Journal: Cell death and differentiation 19980201

Title: Attenuation of ischemia/reperfusion injury in rats by a caspase inhibitor.

Journal: Circulation 19980127

Title: Lysophosphatidic acid induces necrosis and apoptosis in hippocampal neurons.

Journal: Journal of neurochemistry 19980101

Title: Activation of PKCalpha downstream from caspases during apoptosis induced by 7-hydroxystaurosporine or the topoisomerase inhibitors, camptothecin and etoposide, in human myeloid leukemia HL60 cells.

Journal: The Journal of biological chemistry 19971212

Title: Rapid induction of apoptosis by deregulated uptake of polyamine analogues.

Journal: The Biochemical journal 19971115

Title: Interaction of Yersinia enterocolitica with macrophages leads to macrophage cell death through apoptosis.

Journal: Infection and immunity 19971101

Title: Betulinic acid triggers CD95 (APO-1/Fas)- and p53-independent apoptosis via activation of caspases in neuroectodermal tumors.

Journal: Cancer research 19971101

Title: Involvement of the ICE family of proteases in silica-induced apoptosis in human alveolar macrophages.

Journal: The American journal of physiology 19971001

Title: Need for caspases in apoptosis of trophic factor-deprived PC12 cells.

Journal: Journal of neuroscience research 19971001

Title: Retinoblastoma protein-dependent growth signal conflict and caspase activity are required for protein kinase C-signaled apoptosis of prostate epithelial cells.

Journal: The Journal of biological chemistry 19970905

Title: Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis.

Journal: Molecular and cellular biology 19970901

Title: The CD95 (APO-1/Fas) system mediates drug-induced apoptosis in neuroblastoma cells.

Journal: Cancer research 19970901

Title: Induction of apoptosis in Kaposi's sarcoma spindle cell cultures by the subunits of human chorionic gonadotropin.

Journal: AIDS (London, England) 19970901

Title: Involvement of caspase family proteases in transforming growth factor-beta-induced apoptosis.

Journal: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 19970701

Title: Role of calpain- and interleukin-1 beta converting enzyme-like proteases in the beta-amyloid-induced death of rat hippocampal neurons in culture.

Journal: Journal of neurochemistry 19970401

Title: Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19970304

Title: The inhibition of pro-apoptotic ICE-like proteases enhances HIV replication.

Journal: Nature medicine 19970301

Title: Caspase inhibition selectively reduces the apoptotic component of oxygen-glucose deprivation-induced cortical neuronal cell death.

Journal: Molecular and cellular neurosciences 19970101

Title: BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19961210

Title: Different interleukin-1 beta converting enzyme (ICE) family protease requirements for the apoptotic death of T lymphocytes triggered by diverse stimuli.

Journal: The Journal of experimental medicine 19961201

Title: CD95 (APO-1/Fas) induces activation of SAP kinases downstream of ICE-like proteases.

Journal: Oncogene 19961121

Title: Silica-induced apoptosis mediated via scavenger receptor in human alveolar macrophages.

Journal: Toxicology and applied pharmacology 19961101

Title: Systemic injection of a tripeptide inhibits the intracellular activation of CPP32-like proteases in vivo and fully protects mice against Fas-mediated fulminant liver destruction and death.

Journal: The Journal of experimental medicine 19961101

Title: Asbestos induces apoptosis in human alveolar macrophages.

Journal: The American journal of physiology 19961101

Title: Role of Ced-3/ICE-family proteases in staurosporine-induced programmed cell death.

Journal: The Journal of cell biology 19960601

Title: Ligation of CD40 rescues Ramos-Burkitt lymphoma B cells from calcium ionophore- and antigen receptor-triggered apoptosis by inhibiting activation of the cysteine protease CPP32/Yama and cleavage of its substrate PARP.

Journal: FEBS letters 19960520

Title: Role of serine and ICE-like proteases in induction of apoptosis by etoposide in human leukemia HL-60 cells.

Journal: Leukemia 19960501

Title: Requirement of an ICE-like protease for induction of apoptosis and ceramide generation by REAPER.

Journal: Science (New York, N.Y.) 19960209

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Tags:161401-82-7 Molecular Formula|161401-82-7 MDL|161401-82-7 SMILES|161401-82-7 Z-vad-fmk