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167479-78-9,MFCD00270363
Catalog No.:AA00HZ45

167479-78-9 | L-(S)-4-Cyanophenylalanine

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250mg
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$7.00   $5.00
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1g
98%
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$14.00   $10.00
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5g
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$50.00   $35.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00HZ45
Chemical Name:
L-(S)-4-Cyanophenylalanine
CAS Number:
167479-78-9
Molecular Formula:
C10H10N2O2
Molecular Weight:
190.1986
MDL Number:
MFCD00270363
SMILES:
NC(C(=O)O)Cc1ccc(cc1)C#N
Properties
Computed Properties
 
Complexity:
248  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
-1.4  

Literature

Title: Native state conformational heterogeneity of HP35 revealed by time-resolved FRET.

Journal: The journal of physical chemistry. B 20120906

Title: Expanding the utility of 4-cyano-L-phenylalanine as a vibrational reporter of protein environments.

Journal: The journal of physical chemistry. B 20120906

Title: Sensitivity of amyloid formation by human islet amyloid polypeptide to mutations at residue 20.

Journal: Journal of molecular biology 20120810

Title: Modifying the electronic properties of single-walled carbon nanotubes using designed surfactant peptides.

Journal: Nanoscale 20120807

Title: Ribonuclease S dynamics measured using a nitrile label with 2D IR vibrational echo spectroscopy.

Journal: The journal of physical chemistry. B 20120405

Title: High-yield cell-free protein synthesis for site-specific incorporation of unnatural amino acids at two sites.

Journal: Biochemical and biophysical research communications 20120224

Title: An evolved aminoacyl-tRNA synthetase with atypical polysubstrate specificity.

Journal: Biochemistry 20110322

Title: Nitrile bonds as infrared probes of electrostatics in ribonuclease S.

Journal: The journal of physical chemistry. B 20101028

Title: Thioamides as fluorescence quenching probes: minimalist chromophores to monitor protein dynamics.

Journal: Journal of the American Chemical Society 20101027

Title: Differential effects of Phe19 and Phe20 on fibril formation by amyloidogenic peptide A beta 16-22 (Ac-KLVFFAE-NH2).

Journal: Proteins 20100801

Title: Modulation of p-cyanophenylalanine fluorescence by amino acid side chains and rational design of fluorescence probes of alpha-helix formation.

Journal: Biochemistry 20100727

Title: Residue-specific, real-time characterization of lag-phase species and fibril growth during amyloid formation: a combined fluorescence and IR study of p-cyanophenylalanine analogs of islet amyloid polypeptide.

Journal: Journal of molecular biology 20100723

Title: Non-natural amino acid fluorophores for one- and two-step fluorescence resonance energy transfer applications.

Journal: Analytical biochemistry 20100415

Title: Interpretation of p-cyanophenylalanine fluorescence in proteins in terms of solvent exposure and contribution of side-chain quenchers: a combined fluorescence, IR and molecular dynamics study.

Journal: Biochemistry 20090929

Title: FTIR analysis of GPCR activation using azido probes.

Journal: Nature chemical biology 20090601

Title: Mechanism of interaction between the general anesthetic halothane and a model ion channel protein, II: Fluorescence and vibrational spectroscopy using a cyanophenylalanine probe.

Journal: Biophysical journal 20090520

Title: Mechanism of interaction between the general anesthetic halothane and a model ion channel protein, III: Molecular dynamics simulation incorporating a cyanophenylalanine spectroscopic probe.

Journal: Biophysical journal 20090520

Title: Using two fluorescent probes to dissect the binding, insertion, and dimerization kinetics of a model membrane peptide.

Journal: Journal of the American Chemical Society 20090325

Title: Using an amino acid fluorescence resonance energy transfer pair to probe protein unfolding: application to the villin headpiece subdomain and the LysM domain.

Journal: Biochemistry 20081021

Title: The fluorescent amino acid p-cyanophenylalanine provides an intrinsic probe of amyloid formation.

Journal: Chembiochem : a European journal of chemical biology 20080616

Title: Role of helix nucleation in the kinetics of binding of mastoparan X to phospholipid bilayers.

Journal: Biochemistry 20071204

Title: Use of the novel fluorescent amino acid p-cyanophenylalanine offers a direct probe of hydrophobic core formation during the folding of the N-terminal domain of the ribosomal protein L9 and provides evidence for two-state folding.

Journal: Biochemistry 20071030

Title: Site-specific hydration status of an amphipathic peptide in AOT reverse micelles.

Journal: Langmuir : the ACS journal of surfaces and colloids 20071023

Title: New chromogenic substrates of human neutrophil cathepsin G containing non-natural aromatic amino acid residues in position P(1) selected by combinatorial chemistry methods.

Journal: Molecular diversity 20070501

Title: A novel fluorescent probe for protein binding and folding studies: p-cyano-phenylalanine.

Journal: Biopolymers 20061215

Title: A genetically encoded infrared probe.

Journal: Journal of the American Chemical Society 20061101

Title: Probing the kinetics of membrane-mediated helix folding.

Journal: The journal of physical chemistry. B 20060420

Title: Neighbouring group processes in the deamination of protonated phenylalanine derivatives.

Journal: Organic & biomolecular chemistry 20051021

Title: Conformational distribution of a 14-residue peptide in solution: a fluorescence resonance energy transfer study.

Journal: The journal of physical chemistry. B 20050317

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