Title: The synthetic cannabinoid XLR-11 induces in vitro nephrotoxicity by impairment of endocannabinoid-mediated regulation of mitochondrial function homeostasis and triggering of apoptosis.
Journal: Toxicology letters 20180501
Title: WWL70 attenuates PGE(2) production derived from 2-arachidonoylglycerol in microglia by ABHD6-independent mechanism.
Journal: Journal of neuroinflammation 20170101
Title: Parabens inhibit fatty acid amide hydrolase: A potential role in paraben-enhanced 3T3-L1 adipocyte differentiation.
Journal: Toxicology letters 20161116
Title: Cannabinoid receptor interacting protein suppresses agonist-driven CB(1) receptor internalization and regulates receptor replenishment in an agonist-biased manner.
Journal: Journal of neurochemistry 20161101
Title: In Vivo Characterization of the Ultrapotent Monoacylglycerol Lipase Inhibitor {4-[bis-(benzo[d][1,3]dioxol-5-yl)methyl]-piperidin-1-yl}(1H-1,2,4-triazol-1-yl)methanone (JJKK-048).
Journal: The Journal of pharmacology and experimental therapeutics 20161001
Title: Endogenous 2-Arachidonoylglycerol Alleviates Cyclooxygenases-2 Elevation-Mediated Neuronal Injury From SO2 Inhalation via PPARγ Pathway.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20151001
Title: Pharmacological modulation of the endocannabinoid signalling alters binge-type eating behaviour in female rats.
Journal: British journal of pharmacology 20130601
Title: Modeling alcohol self-administration in the human laboratory.
Journal: Current topics in behavioral neurosciences 20130101
Title: Qualitative screening for adulterants in weight-loss supplements by ion mobility spectrometry.
Journal: Journal of pharmaceutical and biomedical analysis 20121201
Title: Structural analogs of pyrazole and sulfonamide cannabinoids: effects on acute food intake in mice.
Journal: European journal of pharmacology 20121115
Title: Rimonabant improves obesity but not the overall cardiovascular risk and quality of life; results from CARDIO-REDUSE (CArdiometabolic Risk reDuctIOn by Rimonabant: the Effectiveness in Daily practice and its USE).
Journal: Family practice 20121001
Title: Recent advances in the pathophysiology and pharmacological treatment of obesity.
Journal: Journal of clinical pharmacy and therapeutics 20121001
Title: The effects of fasting duration on gastric emptying in man, an exploration of the role of the endocannabinoid system and inter-individual responsiveness.
Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20121001
Title: AM-251 and rimonabant act as direct antagonists at mu-opioid receptors: implications for opioid/cannabinoid interaction studies.
Journal: Neuropharmacology 20121001
Title: NESS038C6, a novel selective CB1 antagonist agent with anti-obesity activity and improved molecular profile.
Journal: Behavioural brain research 20121001
Title: Acute myocardial infarction inhibits the neurogenic tachycardic and vasopressor response in rats via presynaptic cannabinoid type 1 receptor.
Journal: The Journal of pharmacology and experimental therapeutics 20121001
Title: Evaluation of the endogenous cannabinoid system in mediating the behavioral effects of dipyrone (metamizol) in mice.
Journal: Behavioural pharmacology 20121001
Title: JD-5006 and JD-5037: peripherally restricted (PR) cannabinoid-1 receptor blockers related to SLV-319 (Ibipinabant) as metabolic disorder therapeutics devoid of CNS liabilities.
Journal: Bioorganic & medicinal chemistry letters 20121001
Title: [Effect of metabolic drugs on the secretion of acylation stimulating protein in 3T3-L1 adipocytes].
Journal: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20121001
Title: 7-Alkyl-3-benzylcoumarins: a versatile scaffold for the development of potent and selective cannabinoid receptor agonists and antagonists.
Journal: Journal of medicinal chemistry 20120927
Title: Angiotensin II induces vascular endocannabinoid release, which attenuates its vasoconstrictor effect via CB1 cannabinoid receptors.
Journal: The Journal of biological chemistry 20120907
Title: Fatty acid flux and oxidation are increased by rimonabant in obese women.
Journal: Metabolism: clinical and experimental 20120901
Title: Cannabinol and cannabidiol exert opposing effects on rat feeding patterns.
Journal: Psychopharmacology 20120901
Title: Cannabinoid receptors mediate methamphetamine induction of high frequency gamma oscillations in the nucleus accumbens.
Journal: Neuropharmacology 20120901
Title: Reports of the death of CB1 antagonists have been greatly exaggerated: recent preclinical findings predict improved safety in the treatment of obesity.
Journal: Behavioural pharmacology 20120901
Title: Selective cannabinoid-1 receptor blockade benefits fatty acid and triglyceride metabolism significantly in weight-stable nonhuman primates.
Journal: American journal of physiology. Endocrinology and metabolism 20120901
Title: Contrasting effects of different cannabinoid receptor ligands on mouse ingestive behaviour.
Journal: Behavioural pharmacology 20120901
Title: Hypothalamic CB1 cannabinoid receptors regulate energy balance in mice.
Journal: Endocrinology 20120901
Title: Second generation CB1 receptor blockers and other inhibitors of peripheral endocannabinoid overactivity and the rationale of their use against metabolic disorders.
Journal: Expert opinion on investigational drugs 20120901
Title: Anandamide regulates the expression of GnRH1, GnRH2, and GnRH-Rs in frog testis.
Journal: American journal of physiology. Endocrinology and metabolism 20120815
Title: Effect of CB1 receptor blockade on food-reinforced responding and associated nucleus accumbens neuronal activity in rats.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120815
Title: Interactions between dopamine transporter and cannabinoid receptor ligands in rhesus monkeys.
Journal: Psychopharmacology 20120801
Title: In silico investigation of interactions between human cannabinoid receptor-1 and its antagonists.
Journal: Journal of molecular modeling 20120801
Title: Inhibition of forebrain μ-opioid receptor signaling by low concentrations of rimonabant does not require cannabinoid receptors and directly involves μ-opioid receptors.
Journal: Neurochemistry international 20120801
Title: Antidepressant-like effects of Δ⁹-tetrahydrocannabinol and rimonabant in the olfactory bulbectomised rat model of depression.
Journal: Pharmacology, biochemistry, and behavior 20120801
Title: Inhibition of fatty acid amide hydrolase by URB597 attenuates the anxiolytic-like effect of acetaminophen in the mouse elevated plus-maze test.
Journal: Behavioural pharmacology 20120801
Title: Cannabinoid receptor 1 in the vagus nerve is dispensable for body weight homeostasis but required for normal gastrointestinal motility.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120725
Title: Activation of type 5 metabotropic glutamate receptors and diacylglycerol lipase-α initiates 2-arachidonoylglycerol formation and endocannabinoid-mediated analgesia.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120711
Title: Effects induced by cannabinoids on monoaminergic systems in the brain and their implications for psychiatric disorders.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20120702
Title: Effect of delta-9-tetrahydrocannabinol on behavioral despair and on pre- and postsynaptic serotonergic transmission.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20120702
Title: Cannabinoid CB₁ receptor restrains accentuated activity of hypothalamic corticotropin-releasing factor and brainstem tyrosine hydroxylase neurons in endotoxemia-induced hypophagia in rats.
Journal: Neuropharmacology 20120701
Title: Photoperiodic changes in endocannabinoid levels and energetic responses to altered signalling at CB1 receptors in Siberian hamsters.
Journal: Journal of neuroendocrinology 20120701
Title: Genetic dissection of the role of cannabinoid type-1 receptors in the emotional consequences of repeated social stress in mice.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20120701
Title: Hyperalgesia by low doses of the local anesthetic lidocaine involves cannabinoid signaling: an fMRI study in mice.
Journal: Pain 20120701
Title: Involvement of a non-CB1/CB2 cannabinoid receptor in the aqueous humor outflow-enhancing effects of abnormal-cannabidiol.
Journal: Experimental eye research 20120701
Title: Effects of palmitoylethanolamide on aqueous humor outflow.
Journal: Investigative ophthalmology & visual science 20120701
Title: Presynaptic CB(1) cannabinoid receptors control frontocortical serotonin and glutamate release--species differences.
Journal: Neurochemistry international 20120701
Title: Long-term depression of nociceptive synapses by non-nociceptive afferent activity: role of endocannabinoids, Ca²+, and calcineurin.
Journal: Brain research 20120615
Title: Design, synthesis, and pharmacological characterization of indol-3-ylacetamides, indol-3-yloxoacetamides, and indol-3-ylcarboxamides: potent and selective CB2 cannabinoid receptor inverse agonists.
Journal: Journal of medicinal chemistry 20120614
Title: Association study of cannabinoid receptor 1 (CNR1) gene in tardive dyskinesia.
Journal: The pharmacogenomics journal 20120601
Title: Molecular mechanisms of diabetes and atherosclerosis: role of adiponectin.
Journal: Endocrine, metabolic & immune disorders drug targets 20120601
Title: Ibipinabant attenuates β-cell loss in male Zucker diabetic fatty rats independently of its effects on body weight.
Journal: Diabetes, obesity & metabolism 20120601
Title: Cannabinoids and atherosclerotic coronary heart disease.
Journal: Clinical cardiology 20120601
Title: A systematic review and mixed treatment comparison of pharmacological interventions for the treatment of obesity.
Journal: Obesity reviews : an official journal of the International Association for the Study of Obesity 20120601
Title: Methamphetamine-induced dopamine terminal deficits in the nucleus accumbens are exacerbated by reward-associated cues and attenuated by CB1 receptor antagonism.
Journal: Neuropharmacology 20120601
Title: Cannabinoids ameliorate disease progression in a model of multiple sclerosis in mice, acting preferentially through CB1 receptor-mediated anti-inflammatory effects.
Journal: Neuropharmacology 20120601
Title: Rimonabant abolishes sensitivity to workload changes in a progressive ratio procedure.
Journal: Pharmacology, biochemistry, and behavior 20120601
Title: Addition of a low dose of rimonabant to orlistat therapy decreases weight gain and reduces adiposity in dietary obese rats.
Journal: Clinical and experimental pharmacology & physiology 20120601
Title: Pleiotropic effects of rimonabant and simvastatin on obesity associated multiple metabolic risk factors in rats.
Journal: European review for medical and pharmacological sciences 20120601
Title: Dual fatty acid amide hydrolase and monoacylglycerol lipase blockade produces THC-like Morris water maze deficits in mice.
Journal: ACS chemical neuroscience 20120516
Title: CB(1) antagonism restores hepatic insulin sensitivity without normalization of adiposity in diet-induced obese dogs.
Journal: American journal of physiology. Endocrinology and metabolism 20120515
Title: Exploiting transport activity of p-glycoprotein at the blood-brain barrier for the development of peripheral cannabinoid type 1 receptor antagonists.
Journal: Molecular pharmaceutics 20120507
Title: Endocannabinoids stimulate human melanogenesis via type-1 cannabinoid receptor.
Journal: The Journal of biological chemistry 20120504
Title: Effects of chronic oral rimonabant administration on energy budgets of diet-induced obese C57BL/6 mice.
Journal: Obesity (Silver Spring, Md.) 20120501
Title: Anti-obesity drugs: a review about their effects and their safety.
Journal: Expert opinion on drug safety 20120501
Title: CB1 receptor antagonists: new discoveries leading to new perspectives.
Journal: Acta physiologica (Oxford, England) 20120501
Title: Food and Drug Administration's Obesity Drug Guidance Document: a short history.
Journal: Circulation 20120501
Title: Allosteric modulator ORG27569 induces CB1 cannabinoid receptor high affinity agonist binding state, receptor internalization, and Gi protein-independent ERK1/2 kinase activation.
Journal: The Journal of biological chemistry 20120406
Title: The cannabinoid CB1 receptor antagonists rimonabant (SR141716) and AM251 directly potentiate GABA(A) receptors.
Journal: British journal of pharmacology 20120401
Title: The endocannabinoid system in the rat dorsolateral periaqueductal grey mediates fear-conditioned analgesia and controls fear expression in the presence of nociceptive tone.
Journal: British journal of pharmacology 20120401
Title: Clozapine impairs insulin action by up-regulating Akt phosphorylation and Ped/Pea-15 protein abundance.
Journal: Journal of cellular physiology 20120401
Title: The GPCR-associated sorting protein 1 regulates ligand-induced down-regulation of GPR55.
Journal: British journal of pharmacology 20120401
Title: Tonic regulation of GABAergic synaptic activity on vasopressin neurones by cannabinoids.
Journal: Journal of neuroendocrinology 20120401
Title: Exogenous and endogenous cannabinoids suppress inhibitory neurotransmission in the human neocortex.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20120401
Title: Inhibitory inputs from rostromedial tegmental neurons regulate spontaneous activity of midbrain dopamine cells and their responses to drugs of abuse.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20120401
Title: Cannabinoid CB1 receptor activation, pharmacological blockade, or genetic ablation affects the function of the muscarinic auto- and heteroreceptor.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20120401
Title: [The potential use of cannabidiol in the therapy of metabolic syndrome].
Journal: Orvosi hetilap 20120401
Title: Design and synthesis of cannabinoid receptor 1 antagonists for peripheral selectivity.
Journal: Journal of medicinal chemistry 20120322
Title: [The pharmacological treatment of obesity: past, present and future].
Journal: Orvosi hetilap 20120311
Title: FAT SIGNALS--lipases and lipolysis in lipid metabolism and signaling.
Journal: Cell metabolism 20120307
Title: Antagonism of peripheral hepatic cannabinoid receptor-1 improves liver lipid metabolism in mice: evidence from cultured explants.
Journal: Hepatology (Baltimore, Md.) 20120301
Title: The CB1 receptor antagonist rimonabant controls cell viability and ascitic tumour growth in mice.
Journal: Pharmacological research 20120301
Title: Effects of the anandamide uptake blocker AM404 on food intake depend on feeding status and route of administration.
Journal: Pharmacology, biochemistry, and behavior 20120301
Title: Endogenous cannabinoid system regulates intestinal barrier function in vivo through cannabinoid type 1 receptor activation.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20120301
Title: Some cannabinoid receptor ligands and their distomers are direct-acting openers of SUR1 K(ATP) channels.
Journal: American journal of physiology. Endocrinology and metabolism 20120301
Title: Does rimonabant independently affect free fatty acid and glucose metabolism?
Journal: The Journal of clinical endocrinology and metabolism 20120301
Title: Sex differences in cannabinoid 1 vs. cannabinoid 2 receptor-selective antagonism of antinociception produced by delta9-tetrahydrocannabinol and CP55,940 in the rat.
Journal: The Journal of pharmacology and experimental therapeutics 20120301
Title: Reversal of liver fibrosis by the antagonism of endocannabinoid CB1 receptor in a rat model of CCl(4)-induced advanced cirrhosis.
Journal: Laboratory investigation; a journal of technical methods and pathology 20120301
Title: Blockade of cannabinoid receptor 1 improves insulin resistance, lipid metabolism, and diabetic nephropathy in db/db mice.
Journal: Endocrinology 20120301
Title: Changes in cannabinoid receptor subtype 1 activity and interaction with metabotropic glutamate subtype 5 receptors in the periaqueductal gray-rostral ventromedial medulla pathway in a rodent neuropathic pain model.
Journal: CNS & neurological disorders drug targets 20120301
Title: The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2-arachidonoylglycerol signalling through cannabinoid receptors.
Journal: Acta physiologica (Oxford, England) 20120201
Title: Involvement of the endocannabinoid system in reward processing in the human brain.
Journal: Psychopharmacology 20120201
Title: Involvement of opioid system in cognitive deficits induced by ∆⁹-tetrahydrocannabinol in rats.
Journal: Psychopharmacology 20120201
Title: Rimonabant reduces the essential value of food in the genetically obese Zucker rat: an exponential demand analysis.
Journal: Physiology & behavior 20120201
Title: 3-Substituted pyrazole analogs of the cannabinoid type 1 (CB₁) receptor antagonist rimonabant: cannabinoid agonist-like effects in mice via non-CB₁, non-CB₂ mechanism.
Journal: The Journal of pharmacology and experimental therapeutics 20120201
Title: Rimonabant for neurocognition in schizophrenia: a 16-week double blind randomized placebo controlled trial.
Journal: Schizophrenia research 20120201
Title: Cannabinoid CB1 receptor mediates glucocorticoid effects on hormone secretion induced by volume and osmotic changes.
Journal: Clinical and experimental pharmacology & physiology 20120201
Title: Latest advances in novel cannabinoid CB(2) ligands for drug abuse and their therapeutic potential.
Journal: Future medicinal chemistry 20120201
Title: Blurred boundaries: the therapeutics and politics of medical marijuana.
Journal: Mayo Clinic proceedings 20120201
Title: Inflammatory cause of metabolic syndrome via brain stress and NF-κB.
Journal: Aging 20120201
Title: Anti-Obesity Drugs: A Review about Their Effects and Safety.
Journal: Diabetes & metabolism journal 20120201
Title: Blocking the postpartum mouse dam's CB1 receptors impairs maternal behavior as well as offspring development and their adult social-emotional behavior.
Journal: Behavioural brain research 20120115
Title: The inverse agonist effect of rimonabant on G protein activation is not mediated by the cannabinoid CB1 receptor: evidence from postmortem human brain.
Journal: Biochemical pharmacology 20120115
Title: Δ9-Tetrahydrocannabinol attenuates MDMA-induced hyperthermia in rhesus monkeys.
Journal: Neuroscience 20120110
Title: SK channel modulation rescues striatal plasticity and control over habit in cannabinoid tolerance.
Journal: Nature neuroscience 20120108
Title: Modulation of L-α-lysophosphatidylinositol/GPR55 mitogen-activated protein kinase (MAPK) signaling by cannabinoids.
Journal: The Journal of biological chemistry 20120102
Title: Innate difference in the endocannabinoid signaling and its modulation by alcohol consumption in alcohol-preferring sP rats.
Journal: Addiction biology 20120101
Title: Effects of 7 days of treatment with the cannabinoid type 1 receptor antagonist, rimonabant, on emotional processing.
Journal: Journal of psychopharmacology (Oxford, England) 20120101
Title: Cannabinoid receptor stimulation increases motivation for nicotine and nicotine seeking.
Journal: Addiction biology 20120101
Title: CB1 receptor antagonism/inverse agonism increases motor system excitability in humans.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20120101
Title: The changes in plasma retinol-binding protein 4 levels are associated with those of the apolipoprotein B-containing lipoproteins during dietary and drug treatment.
Journal: Angiology 20120101
Title: The endocannabinoid system in anxiety, fear memory and habituation.
Journal: Journal of psychopharmacology (Oxford, England) 20120101
Title: CB1 - cannabinoid receptor antagonist effects on cortisol in cannabis-dependent men.
Journal: The American journal of drug and alcohol abuse 20120101
Title: Magnesium deficiency induces anxiety and HPA axis dysregulation: modulation by therapeutic drug treatment.
Journal: Neuropharmacology 20120101
Title: Immunoregulation of experimental autoimmune encephalomyelitis by the selective CB1 receptor antagonist.
Journal: Journal of neuroscience research 20120101
Title: Rimonabant attenuates amphetamine sensitisation in a CCK2 receptor-dependent manner.
Journal: Behavioural brain research 20120101
Title: Expression of fatty acid amide hydrolase (FAAH) in human, mouse, and rat urinary bladder and effects of FAAH inhibition on bladder function in awake rats.
Journal: European urology 20120101
Title: JWH-018 and JWH-073: Δ⁹-tetrahydrocannabinol-like discriminative stimulus effects in monkeys.
Journal: The Journal of pharmacology and experimental therapeutics 20120101
Title: The effects of chronic administration of tranylcypromine and rimonabant on behaviour and protein expression in brain regions of the rat.
Journal: Pharmacology, biochemistry, and behavior 20120101
Title: Detection of hazardous weight-loss substances in adulterated slimming formulations using ultra-high-pressure liquid chromatography with diode-array detection.
Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101
Title: Does innovation in obesity drugs affect stock markets? An event study analysis.
Journal: Gaceta sanitaria 20120101
Title: Central and peripheral cannabinoid receptors as therapeutic targets in the control of food intake and body weight.
Journal: Handbook of experimental pharmacology 20120101
Title: Stress hormones receptors in the amygdala mediate the effects of stress on the consolidation, but not the retrieval, of a non aversive spatial task.
Journal: PloS one 20120101
Title: Pharmacological interventions in the treatment of the acute effects of cannabis: a systematic review of literature.
Journal: Harm reduction journal 20120101
Title: Amyloid precursor protein and proinflammatory changes are regulated in brain and adipose tissue in a murine model of high fat diet-induced obesity.
Journal: PloS one 20120101
Title: Randomized, double-blind, placebo-controlled, linear dose, crossover study to evaluate the efficacy and safety of a green coffee bean extract in overweight subjects.
Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20120101
Title: Effects of a selective cannabinoid CB2 agonist and antagonist on intravenous nicotine self administration and reinstatement of nicotine seeking.
Journal: PloS one 20120101
Title: Lipidomics reveals multiple pathway effects of a multi-components preparation on lipid biochemistry in ApoE*3Leiden.CETP mice.
Journal: PloS one 20120101
Title: What is the clinical effectiveness and cost-effectiveness of using drugs in treating obese patients in primary care? A systematic review.
Journal: Health technology assessment (Winchester, England) 20120101
Title: Endocannabinoids and the processing of value-related signals.
Journal: Frontiers in pharmacology 20120101
Title: Decreased reward sensitivity in rats from the Fischer344 strain compared to Wistar rats is paralleled by differences in endocannabinoid signaling.
Journal: PloS one 20120101
Title: Short- and long-term cognitive effects of chronic cannabinoids administration in late-adolescence rats.
Journal: PloS one 20120101
Title: Decreased prevalence of diabetes in marijuana users: cross-sectional data from the National Health and Nutrition Examination Survey (NHANES) III.
Journal: BMJ open 20120101
Title: Serum contents of endocannabinoids are correlated with blood pressure in depressed women.
Journal: Lipids in health and disease 20120101
Title: Gut Hormones and Appetite Control: A Focus on PYY and GLP-1 as Therapeutic Targets in Obesity.
Journal: Gut and liver 20120101
Title: Differences in spontaneously avoiding or approaching mice reflect differences in CB1-mediated signaling of dorsal striatal transmission.
Journal: PloS one 20120101
Title: Alterations to melanocortinergic, GABAergic and cannabinoid neurotransmission associated with olanzapine-induced weight gain.
Journal: PloS one 20120101
Title: The endocannabinoid transport inhibitor AM404 differentially modulates recognition memory in rats depending on environmental aversiveness.
Journal: Frontiers in behavioral neuroscience 20120101
Title: The endocannabinoid system: an overview.
Journal: Frontiers in behavioral neuroscience 20120101
Title: Do placebo response rates from cessation trials inform on strength of addictions?
Journal: International journal of environmental research and public health 20120101
Title: Combination Drug Therapy for Pain following Chronic Spinal Cord Injury.
Journal: Pain research and treatment 20120101
Title: Reversible disruption of pre-pulse inhibition in hypomorphic-inducible and reversible CB1-/- mice.
Journal: PloS one 20120101
Title: Desipramine inhibits histamine H1 receptor-induced Ca2+ signaling in rat hypothalamic cells.
Journal: PloS one 20120101
Title: CNR1 genotype influences HDL-cholesterol response to change in dietary fat intake.
Journal: PloS one 20120101
Title: A novel method for determination of drug distribution in rat brain tissue sections by LC/MS/MS: functional tissue microanalysis.
Journal: Current topics in medicinal chemistry 20120101
Title: Update on the role of cannabinoid receptors after ischemic stroke.
Journal: Mediators of inflammation 20120101
Title: Public health concerns for anti-obesity medicines imported for personal use through the internet: a cross-sectional study.
Journal: BMJ open 20120101
Title: Dysfunction in fatty acid amide hydrolase is associated with depressive-like behavior in Wistar Kyoto rats.
Journal: PloS one 20120101
Title: Role of Gut-Related Peptides and Other Hormones in the Amelioration of Type 2 Diabetes after Roux-en-Y Gastric Bypass Surgery.
Journal: ISRN endocrinology 20120101
Title: RP-HPLC Method Development and Its Validation for Quantitative Determination of Rimonabant in Human Plasma.
Journal: Journal of analytical methods in chemistry 20120101
Title: Effects of cannabinoid receptor agonist WIN 55,212-2 on blood-brain barrier disruption in focal cerebral ischemia in rats.
Journal: Pharmacology 20120101
Title: Induction of glucose intolerance by acute administration of rimonabant.
Journal: Pharmacology 20120101
Title: On the Role of Cannabinoid CB1- and μ-Opioid Receptors in Motor Impulsivity.
Journal: Frontiers in pharmacology 20120101
Title: Endocannabinoid modulation of dopaminergic motor circuits.
Journal: Frontiers in pharmacology 20120101
Title: Metabolic effects of n-3 PUFA as phospholipids are superior to triglycerides in mice fed a high-fat diet: possible role of endocannabinoids.
Journal: PloS one 20120101
Title: Antipsychotic profile of cannabidiol and rimonabant in an animal model of emotional context processing in schizophrenia.
Journal: Current pharmaceutical design 20120101
Title: Antipsychotic-like effects of cannabidiol and rimonabant: systematic review of animal and human studies.
Journal: Current pharmaceutical design 20120101
Title: The endocannabinoid system and schizophrenia: integration of evidence.
Journal: Current pharmaceutical design 20120101
Title: Effect of anti-obesity drug on cardiovascular risk factors: a systematic review and meta-analysis of randomized controlled trials.
Journal: PloS one 20120101
Title: Targeted inactivation of GPR26 leads to hyperphagia and adiposity by activating AMPK in the hypothalamus.
Journal: PloS one 20120101
Title: Relationships between glucose, energy intake and dietary composition in obese adults with type 2 diabetes receiving the cannabinoid 1 (CB1) receptor antagonist, rimonabant.
Journal: Nutrition journal 20120101
Title: Homology modelling of CB1 receptor and selection of potential inhibitor against Obesity.
Journal: Bioinformation 20120101
Title: Coordinated improvement in glucose tolerance, liver steatosis and obesity-associated inflammation by cannabinoid 1 receptor antagonism in fat Aussie mice.
Journal: International journal of obesity (2005) 20111201
Title: Retinol-binding protein 4 : a possible role in cardiovascular complications.
Journal: British journal of pharmacology 20111201
Title: Inhibition of cerebral type 1 cannabinoid receptors is associated with impaired auditory mismatch negativity generation in the ketamine model of schizophrenia.
Journal: Psychopharmacology 20111201
Title: Naloxone and rimonabant reduce the reinforcing properties of exercise in rats.
Journal: Experimental and clinical psychopharmacology 20111201
Title: Endocannabinoids and prostaglandins both contribute to GnRH neuron-GABAergic afferent local feedback circuits.
Journal: Journal of neurophysiology 20111201
Title: Characterization of a novel, brain-penetrating CB1 receptor inverse agonist: metabolic profile in diet-induced obese models and aspects of central activity.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20111201
Title: Centrally mediated antinociceptive effects of cannabinoid receptor ligands in rat models of nociception.
Journal: Pharmacology, biochemistry, and behavior 20111201
Title: Cannabinoid receptor 1 (CB1) antagonism enhances glucose utilisation and activates brown adipose tissue in diet-induced obese mice.
Journal: Diabetologia 20111201
Title: ANKK1/DRD2 locus variants are associated with rimonabant efficacy in aiding smoking cessation: pilot data.
Journal: Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20111201
Title: Positron emission tomographic imaging of the cannabinoid type 1 receptor system with [¹¹C]OMAR ([¹¹C]JHU75528): improvements in image quantification using wild-type and knockout mice.
Journal: Molecular imaging 20111201
Title: Prescribed drugs and violence: a case/noncase study in the French PharmacoVigilance Database.
Journal: European journal of clinical pharmacology 20111101
Title: Rimonabant, a cannabinoid receptor type 1 inverse agonist, inhibits hepatocyte lipogenesis by activating liver kinase B1 and AMP-activated protein kinase axis downstream of Gα i/o inhibition.
Journal: Molecular pharmacology 20111101
Title: Perinatal exposure to Δ9-tetrahydrocannabinol triggers profound defects in T cell differentiation and function in fetal and postnatal stages of life, including decreased responsiveness to HIV antigens.
Journal: The Journal of pharmacology and experimental therapeutics 20111101
Title: Large size cells in the visceral adipose depot predict insulin resistance in the canine model.
Journal: Obesity (Silver Spring, Md.) 20111101
Title: Effects of the cannabinoid antagonist SR 141716 on sexual and motor behaviour in receptive female rats.
Journal: Clinical and experimental pharmacology & physiology 20111101
Title: A role for the ventral hippocampal endocannabinoid system in fear-conditioned analgesia and fear responding in the presence of nociceptive tone in rats.
Journal: Pain 20111101
Title: 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide: an effective scaffold for the design of either CB1 or CB2 receptor ligands.
Journal: European journal of medicinal chemistry 20111101
Title: Negative inotropic effect of a CB2 agonist A-955840 in isolated rabbit ventricular myocytes is independent of CB1 and CB2 receptors.
Journal: Current drug safety 20111101
Title: Genetic deletion of monoacylglycerol lipase alters endocannabinoid-mediated retrograde synaptic depression in the cerebellum.
Journal: The Journal of physiology 20111015
Title: The endocannabinoid 2-arachidonoylglycerol mediates D1 and D2 receptor cooperative enhancement of rat nucleus accumbens core neuron firing.
Journal: Neuroscience 20111013
Title: CRIP1a switches cannabinoid receptor agonist/antagonist-mediated protection from glutamate excitotoxicity.
Journal: Neuroscience letters 20111010
Title: Nonopioid placebo analgesia is mediated by CB1 cannabinoid receptors.
Journal: Nature medicine 20111002
Title: delta(9)-Tetrahydrocannabinol-dependent mice undergoing withdrawal display impaired spatial memory.
Journal: Psychopharmacology 20111001
Title: Activation by 2-arachidonoylglycerol of platelet p38MAPK/cPLA2 pathway.
Journal: Journal of cellular biochemistry 20111001
Title: Cannabinoid CB1 receptor antagonist rimonabant disrupts nicotine reward-associated memory in rats.
Journal: Pharmacology, biochemistry, and behavior 20111001
Title: Pro-epileptic effects of the cannabinoid receptor antagonist SR141716 in a model of audiogenic epilepsy.
Journal: Epilepsy research 20111001
Title: Bioactivation pathways of the cannabinoid receptor 1 antagonist rimonabant.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20111001
Title: Fatty acid amide hydrolase blockade attenuates the development of collagen-induced arthritis and related thermal hyperalgesia in mice.
Journal: Pharmacology, biochemistry, and behavior 20111001
Title: The G protein-coupled cannabinoid-1 (CB1) receptor of mammalian brain: inhibition by phthalate esters in vitro.
Journal: Neurochemistry international 20111001
Title: The central cannabinoid CB1 receptor is required for diet-induced obesity and rimonabant's antiobesity effects in mice.
Journal: Obesity (Silver Spring, Md.) 20111001
Title: CNS opioid signaling separates cannabinoid receptor 1-mediated effects on body weight and mood-related behavior in mice.
Journal: Endocrinology 20111001
Title: Antagonist-elicited cannabis withdrawal in humans.
Journal: Journal of clinical psychopharmacology 20111001
Title: Towards rational design of cannabinoid receptor 1 (CB1) antagonists for peripheral selectivity.
Journal: Bioorganic & medicinal chemistry letters 20111001
Title: Retention and extinction of delay eyeblink conditioning are modulated by central cannabinoids.
Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20111001
Title: Neuropsychiatric adverse effects of centrally acting antiobesity drugs.
Journal: CNS neuroscience & therapeutics 20111001
Title: Cannabinoid 1 G protein-coupled receptor (periphero-)neutral antagonists: emerging therapeutics for treating obesity-driven metabolic disease and reducing cardiovascular risk.
Journal: Expert opinion on drug discovery 20111001
Title: [The role of the cannabinoid system in the pathogenesis and treatment of alcohol dependence].
Journal: Postepy higieny i medycyny doswiadczalnej (Online) 20110916
Title: Activation of spinal and supraspinal cannabinoid-1 receptors leads to antinociception in a rat model of neuropathic spinal cord injury pain.
Journal: Brain research 20110915
Title: Fluorinated cannabinoid CB2 receptor ligands: synthesis and in vitro binding characteristics of 2-oxoquinoline derivatives.
Journal: Bioorganic & medicinal chemistry 20110915
Title: Hedonic and incentive signals for body weight control.
Journal: Reviews in endocrine & metabolic disorders 20110901
Title: The fatty acid amide hydrolase inhibitor URB 597: interactions with anandamide in rhesus monkeys.
Journal: British journal of pharmacology 20110901
Title: The D2 antagonist sulpiride modulates the neural processing of both rewarding and aversive stimuli in healthy volunteers.
Journal: Psychopharmacology 20110901
Title: Extinction learning of rewards in the rat: is there a role for CB1 receptors?
Journal: Psychopharmacology 20110901
Title: Enhancement of endocannabinoid signaling with JZL184, an inhibitor of the 2-arachidonoylglycerol hydrolyzing enzyme monoacylglycerol lipase, produces anxiolytic effects under conditions of high environmental aversiveness in rats.
Journal: Pharmacological research 20110901
Title: Dissimilar cannabinoid substitution patterns in mice trained to discriminate Δ(9)-tetrahydrocannabinol or methanandamide from vehicle.
Journal: Behavioural pharmacology 20110901
Title: Safety of new medicines in young children.
Journal: Archives of disease in childhood 20110901
Title: Cannabinergic aminoalkylindoles, including AM678=JWH018 found in 'Spice', examined using drug (Δ(9)-tetrahydrocannabinol) discrimination for rats.
Journal: Behavioural pharmacology 20110901
Title: Direct injection of lipophilic compounds in the organic phase from liquid-liquid extracted plasma samples onto a reversed-phase column.
Journal: Bioanalysis 20110901
Title: Structure-activity relationship studies of novel pyrazole and imidazole carboxamides as cannabinoid-1 (CB1) antagonists.
Journal: Bioorganic & medicinal chemistry letters 20110815
Title: Investigations on the 4-quinolone-3-carboxylic acid motif. 4. Identification of new potent and selective ligands for the cannabinoid type 2 receptor with diverse substitution patterns and antihyperalgesic effects in mice.
Journal: Journal of medicinal chemistry 20110811
Title: Current and future drug targets in weight management.
Journal: Pharmaceutical research 20110801
Title: CB1 receptors mediate rimonabant-induced pruritic responses in mice: investigation of locus of action.
Journal: Psychopharmacology 20110801
Title: Central mediation and differential blockade by cannabinergics of the discriminative stimulus effects of the cannabinoid CB1 receptor antagonist rimonabant in rats.
Journal: Psychopharmacology 20110801
Title: Differential effect of opioid and cannabinoid receptor blockade on heroin-seeking reinstatement and cannabinoid substitution in heroin-abstinent rats.
Journal: British journal of pharmacology 20110801
Title: Increasing endogenous 2-arachidonoylglycerol levels counteracts colitis and related systemic inflammation.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110801
Title: Memory encoding in hippocampal ensembles is negatively influenced by cannabinoid CB1 receptors.
Journal: Behavioural pharmacology 20110801
Title: [Pharmacological concepts for the treatment of obesity - a therapeutic meander?].
Journal: Deutsche medizinische Wochenschrift (1946) 20110801
Title: Progress in structure based drug design for G protein-coupled receptors.
Journal: Journal of medicinal chemistry 20110714
Title: The use of an improved intragastric balloon technique to reduce weight in pre-obese patients--preliminary results.
Journal: Obesity surgery 20110701
Title: CB-1 receptors modulate the effect of the selective serotonin reuptake inhibitor, citalopram on extracellular serotonin levels in the rat prefrontal cortex.
Journal: Neuroscience research 20110701
Title: Species independence in brain tissue binding using brain homogenates.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110701
Title: Rimonabant redux and strategies to improve the future outlook of CB1 receptor neutral-antagonist/inverse-agonist therapies.
Journal: Obesity (Silver Spring, Md.) 20110701
Title: Diacylglycerol lipase-alpha and -beta control neurite outgrowth in neuro-2a cells through distinct molecular mechanisms.
Journal: Molecular pharmacology 20110701
Title: Cannabinoid type 1 receptor antagonists modulate transport activity of multidrug resistance-associated proteins MRP1, MRP2, MRP3, and MRP4.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110701
Title: Effect of rimonabant on carotid intima-media thickness (CIMT) progression in patients with abdominal obesity and metabolic syndrome: the AUDITOR Trial.
Journal: Heart (British Cardiac Society) 20110701
Title: Tolerance and cross-tolerance to cannabinoids in mice: schedule-controlled responding and hypothermia.
Journal: Psychopharmacology 20110601
Title: Effects of morphine on pain-elicited and pain-suppressed behavior in CB1 knockout and wildtype mice.
Journal: Psychopharmacology 20110601
Title: Cannabinoid 1 receptor activation contributes to vascular inflammation and cell death in a mouse model of diabetic retinopathy and a human retinal cell line.
Journal: Diabetologia 20110601
Title: Disruptive effects of the prototypical cannabinoid Δ⁹-tetrahydrocannabinol and the fatty acid amide inhibitor URB-597 on go/no-go auditory discrimination performance and olfactory reversal learning in rats.
Journal: Behavioural pharmacology 20110601
Title: Propofol enhances memory formation via an interaction with the endocannabinoid system.
Journal: Anesthesiology 20110601
Title: Rimonabant improves cholesterol, insulin resistance and markers of non-alcoholic fatty liver in morbidly obese patients: a retrospective cohort study.
Journal: International journal of clinical practice 20110601
Title: Risk of depressive episodes with rimonabant: a before and after modified prescription event monitoring study conducted in England.
Journal: Drug safety 20110601
Title: The development and description of the comparison group in the Look AHEAD trial.
Journal: Clinical trials (London, England) 20110601
Title: Leptin potentiates the anti-obesity effects of rimonabant.
Journal: European journal of pharmacology 20110511
Title: The endogenous cannabinoid 2-arachidonoylglycerol is intravenously self-administered by squirrel monkeys.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110511
Title: Cannabinoid receptor activation modifies NMDA receptor mediated release of intracellular calcium: implications for endocannabinoid control of hippocampal neural plasticity.
Journal: Neuropharmacology 20110501
Title: Cannabinoid potentiation of glycine receptors contributes to cannabis-induced analgesia.
Journal: Nature chemical biology 20110501
Title: The hypothermic response to bacterial lipopolysaccharide critically depends on brain CB1, but not CB2 or TRPV1, receptors.
Journal: The Journal of physiology 20110501
Title: Personalized medicine can pave the way for the safe use of CB₁ receptor antagonists.
Journal: Trends in pharmacological sciences 20110501
Title: N-(4-cyanotetrahydro-2H-pyran-4-yl) and N-(1-cyanocyclohexyl) derivatives of 1,5-diarylpyrazole-3-carboxamides showing high affinity for 18 kDa translocator protein and/or cannabinoid receptors.
Journal: Journal of medicinal chemistry 20110428
Title: Acute treatment with cannabinoid receptor agonist WIN55212.2 improves prepulse inhibition in psychosocially stressed mice.
Journal: Behavioural brain research 20110415
Title: The endogenous cannabinoid anandamide shares discriminative stimulus effects with ∆(9)-tetrahydrocannabinol in fatty acid amide hydrolase knockout mice.
Journal: European journal of pharmacology 20110410
Title: An straightforward entry to new pyrazolo-fused dibenzo[1,4]diazepines.
Journal: Organic & biomolecular chemistry 20110407
Title: Design, synthesis and biological evaluation of CB1 cannabinoid receptor ligands derived from the 1,5-diarylpyrazole scaffold.
Journal: Journal of enzyme inhibition and medicinal chemistry 20110401
Title: Binding properties of antagonists to cannabinoid receptors in intact cells.
Journal: Fundamental & clinical pharmacology 20110401
Title: Sensitization to cocaine is inhibited after intra-accumbal GR103691 or rimonabant, but it is enhanced after co-infusion indicating functional interaction between accumbens D(3) and CB1 receptors.
Journal: Psychopharmacology 20110401
Title: Additive effects of cannabinoid CB1 receptors blockade and cholecystokinin on feeding inhibition.
Journal: Pharmacology, biochemistry, and behavior 20110401
Title: Pharmacology of GPR55 in yeast and identification of GSK494581A as a mixed-activity glycine transporter subtype 1 inhibitor and GPR55 agonist.
Journal: The Journal of pharmacology and experimental therapeutics 20110401
Title: Pharmacokinetic optimisation of novel indole-2-carboxamide cannabinoid CB1 antagonists.
Journal: Bioorganic & medicinal chemistry letters 20110401
Title: Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells.
Journal: Diabetes 20110401
Title: Discovery of indole alkaloids with cannabinoid CB1 receptor antagonistic activity.
Journal: Bioorganic & medicinal chemistry letters 20110401
Title: Feedback and lessons from the prescription of rimonabant, a drug to be used under strict guidelines, in southeastern France, March 2007 through June 2008.
Journal: Revue d'epidemiologie et de sante publique 20110401
Title: Central endocannabinoid signaling regulates hepatic glucose production and systemic lipolysis.
Journal: Diabetes 20110401
Title: Investigations of the endocannabinoid system in adipose tissue: effects of obesity/ weight loss and treatment options.
Journal: Danish medical bulletin 20110401
Title: Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism.
Journal: Cell death & disease 20110401
Title: Newer molecules in the treatment of schizophrenia: A clinical update.
Journal: Indian journal of pharmacology 20110401
Title: Effect of Argyreia speciosa root extract on cafeteria diet-induced obesity in rats.
Journal: Indian journal of pharmacology 20110401
Title: [Anandamide inhibits the growth of colorectal cancer cells through CB1 and lipid rafts].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20110401
Title: Endocannabinoid 2-arachidonoylglycerol protects neurons against β-amyloid insults.
Journal: Neuroscience 20110331
Title: Cannabinoid type 1 receptor antagonists for smoking cessation.
Journal: The Cochrane database of systematic reviews 20110316
Title: Pharmacological activation of kainate receptors drives endocannabinoid mobilization.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110302
Title: Effect of the cannabinoid receptor-1 antagonist rimonabant on inflammation in mice with diet-induced obesity.
Journal: Obesity (Silver Spring, Md.) 20110301
Title: Nigrostriatal denervation changes the effect of cannabinoids on subthalamic neuronal activity in rats.
Journal: Psychopharmacology 20110301
Title: Evaluation of the emotional phenotype and serotonergic neurotransmission of fatty acid amide hydrolase-deficient mice.
Journal: Psychopharmacology 20110301
Title: Role of the endocannabinoid system in food intake, energy homeostasis and regulation of the endocrine pancreas.
Journal: Pharmacology & therapeutics 20110301
Title: Weight loss induced by rimonabant is associated with an altered leptin expression and hypothalamic leptin signaling in diet-induced obese mice.
Journal: Behavioural brain research 20110301
Title: Chronic Δ⁹-tetrahydrocannabinol treatment in rhesus monkeys: differential tolerance and cross-tolerance among cannabinoids.
Journal: British journal of pharmacology 20110301
Title: Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay.
Journal: Pharmacology, biochemistry, and behavior 20110301
Title: Ligand-induced internalization of the orexin OX(1) and cannabinoid CB(1) receptors assessed via N-terminal SNAP and CLIP-tagging.
Journal: British journal of pharmacology 20110301
Title: Central and peripheral endocannabinoids and cognate acylethanolamides in humans: association with race, adiposity, and energy expenditure.
Journal: The Journal of clinical endocrinology and metabolism 20110301
Title: Effect of rimonabant on oesophageal motor function in man.
Journal: Alimentary pharmacology & therapeutics 20110301
Title: Altered Mesolimbic Dopamine System in THC Dependence.
Journal: Current neuropharmacology 20110301
Title: Commentary: Functional Neuronal CB2 Cannabinoid Receptors in the CNS.
Journal: Current neuropharmacology 20110301
Title: [Long-term effects of weight-reducing drugs in hypertensive patients--a survey of a Cochrane review].
Journal: Ugeskrift for laeger 20110221
Title: Rise and fall of anti-obesity drugs.
Journal: World journal of diabetes 20110215
Title: Effects of cannabinoid CB₁ receptor antagonist rimonabant on acquisition and reinstatement of psychostimulant reward memory in mice.
Journal: Behavioural brain research 20110202
Title: Conditioned cues for smoking elicit preparatory responses in healthy smokers.
Journal: Psychopharmacology 20110201
Title: Effects of drugs of abuse on putative rostromedial tegmental neurons, inhibitory afferents to midbrain dopamine cells.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20110201
Title: Purine receptor-mediated endocannabinoid production and retrograde synaptic signalling in the cerebellar cortex.
Journal: British journal of pharmacology 20110201
Title: Three-dimensional quantitative structure-selectivity relationships analysis guided rational design of a highly selective ligand for the cannabinoid receptor 2.
Journal: European journal of medicinal chemistry 20110201
Title: Effects of the cannabinoid-1 receptor antagonist rimonabant on psychiatric symptoms in overweight people with schizophrenia: a randomized, double-blind, pilot study.
Journal: Journal of clinical psychopharmacology 20110201
Title: An overview of the metabolic effects of rimonabant in randomized controlled trials: potential for other cannabinoid 1 receptor blockers in obesity.
Journal: Journal of clinical pharmacy and therapeutics 20110201
Title: Pharmacotherapy for obese adolescents.
Journal: Pediatric clinics of North America 20110201
Title: IVUS-based imaging modalities for tissue characterization: similarities and differences.
Journal: The international journal of cardiovascular imaging 20110201
Title: Assessment of coronary atherosclerosis by IVUS and IVUS-based imaging modalities: progression and regression studies, tissue composition and beyond.
Journal: The international journal of cardiovascular imaging 20110201
Title: Structural and pharmacological analysis of O-2050, a putative neutral cannabinoid CB(1) receptor antagonist.
Journal: European journal of pharmacology 20110125
Title: The putative cannabinoid receptor GPR55 defines a novel autocrine loop in cancer cell proliferation.
Journal: Oncogene 20110113
Title: The identification of rimonabant polymorphs, sibutramine and analogues of both in counterfeit Acomplia bought on the internet.
Journal: Journal of pharmaceutical and biomedical analysis 20110105
Title: The CB₁ receptor antagonist SR141716A reverses adult male mice overweight and metabolic alterations induced by early stress.
Journal: Obesity (Silver Spring, Md.) 20110101
Title: The CB-1 receptor antagonist rimonabant modulates the interaction between adipocytes and pancreatic beta-cells in vitro.
Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20110101
Title: The CB2 cannabinoid receptor-selective agonist O-3223 reduces pain and inflammation without apparent cannabinoid behavioral effects.
Journal: Neuropharmacology 20110101
Title: Rimonabant reduces keratinocyte viability by induction of apoptosis and exerts topical anti-inflammatory activity in mice.
Journal: British journal of pharmacology 20110101
Title: Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease.
Journal: Brain : a journal of neurology 20110101
Title: Anti-inflammatory nutrition as a pharmacological approach to treat obesity.
Journal: Journal of obesity 20110101
Title: Upregulation of cannabinoid type 1 receptors in dopamine D2 receptor knockout mice is reversed by chronic forced ethanol consumption.
Journal: Alcoholism, clinical and experimental research 20110101
Title: Psychiatric adverse effects of rimonobant in adults with Prader Willi syndrome.
Journal: European journal of medical genetics 20110101
Title: Effects of cannabinoid CB1 receptor agonism and antagonism on SKF81297-induced dyskinesia and haloperidol-induced dystonia in Cebus apella monkeys.
Journal: Neuropharmacology 20110101
Title: The role of endocannabinoids in visceral hyposensitivity induced by rapid eye movement sleep deprivation in rats: regional differences.
Journal: International journal of molecular medicine 20110101
Title: Taking Orlistat: Predicting Weight Loss over 6 Months.
Journal: Journal of obesity 20110101
Title: Metformin may maintain weight loss in obese patients with dysglycaemia initially treated with rimonabant.
Journal: Diabetic medicine : a journal of the British Diabetic Association 20110101
Title: Pharmacotherapies for obesity: past, current, and future therapies.
Journal: Journal of obesity 20110101
Title: Pharmacological treatment of obesity in patients with polycystic ovary syndrome.
Journal: Journal of obesity 20110101
Title: Pharmacological treatment of obesity in children and adolescents: present and future.
Journal: Journal of obesity 20110101
Title: Perspectives of CB1 Antagonist in Treatment of Obesity: Experience of RIO-Asia.
Journal: Journal of obesity 20110101
Title: The use of lorcaserin in the management of obesity: a critical appraisal.
Journal: Drug design, development and therapy 20110101
Title: Drug-induced psychosis: how to avoid star gazing in schizophrenia research by looking at more obvious sources of light.
Journal: Frontiers in behavioral neuroscience 20110101
Title: Influence of Sleeve Gastrectomy on NASH and Type 2 Diabetes Mellitus.
Journal: Journal of obesity 20110101
Title: Pharmacological and non-pharmacological interventions to influence adipose tissue function.
Journal: Cardiovascular diabetology 20110101
Title: Krill oil significantly decreases 2-arachidonoylglycerol plasma levels in obese subjects.
Journal: Nutrition & metabolism 20110101
Title: Molecular mechanisms for the destabilization and restabilization of reactivated spatial memory in the Morris water maze.
Journal: Molecular brain 20110101
Title: Present and future: pharmacologic treatment of obesity.
Journal: Journal of obesity 20110101
Title: Regulation of vascular tone by adipocytes.
Journal: BMC medicine 20110101
Title: Bioequivalence study of two tablet formulations containing rimonabant 20 mg in healthy Indian subjects.
Journal: Arzneimittel-Forschung 20110101
Title: Endocannabinoid system protects against cryptogenic seizures.
Journal: Pharmacological reports : PR 20110101
Title: A new perspective of cannabinoid 1 receptor antagonists: approaches toward peripheral CB1R blockers without crossing the blood-brain barrier.
Journal: Current topics in medicinal chemistry 20110101
Title: Analysis of in vitro bioactivity data extracted from drug discovery literature and patents: Ranking 1654 human protein targets by assayed compounds and molecular scaffolds.
Journal: Journal of cheminformatics 20110101
Title: Predicting drug side-effect profiles: a chemical fragment-based approach.
Journal: BMC bioinformatics 20110101
Title: Targeting nicotine addiction: the possibility of a therapeutic vaccine.
Journal: Drug design, development and therapy 20110101
Title: Plasma and liver lipidomics response to an intervention of rimonabant in ApoE*3Leiden.CETP transgenic mice.
Journal: PloS one 20110101
Title: Longer term effects of very low energy diet on obstructive sleep apnoea in cohort derived from randomised controlled trial: prospective observational follow-up study.
Journal: BMJ (Clinical research ed.) 20110101
Title: Evaluation of efficacy and safety of orlistat in obese patients.
Journal: Indian journal of endocrinology and metabolism 20110101
Title: The role of cannabinoids in modulating emotional and non-emotional memory processes in the hippocampus.
Journal: Frontiers in behavioral neuroscience 20110101
Title: Pharmacological evidence for different populations of postsynaptic adenosine A2A receptors in the rat striatum.
Journal: Neuropharmacology 20110101
Title: Dyslipidemia induced by drugs used for the prevention and treatment of vascular diseases.
Journal: The open cardiovascular medicine journal 20110101
Title: Rimonabant: From RIO to Ban.
Journal: Journal of obesity 20110101
Title: Usage, risk, and benefit of weight-loss drugs in primary care.
Journal: Journal of obesity 20110101
Title: Predictors of weight loss and maintenance in patients treated with antiobesity drugs.
Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20110101
Title: AM251, cannabinoids receptors ligand, improves recognition memory in rats.
Journal: Pharmacological reports : PR 20110101
Title: Cannabinoid receptor type I modulates alcohol-induced liver fibrosis.
Journal: Molecular medicine (Cambridge, Mass.) 20110101
Title: Pharmacological activation/inhibition of the cannabinoid system affects alcohol withdrawal-induced neuronal hypersensitivity to excitotoxic insults.
Journal: PloS one 20110101
Title: Effects of cannabinoid agonists on sheep sphincter of oddi in vitro.
Journal: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20110101
Title: Effects of endocannabinoid system modulation on cognitive and emotional behavior.
Journal: Frontiers in behavioral neuroscience 20110101
Title: Endocannabinoid system in cardiovascular disorders - new pharmacotherapeutic opportunities.
Journal: Journal of pharmacy & bioallied sciences 20110101
Title: Market Access Agreements for pharmaceuticals in Europe: diversity of approaches and underlying concepts.
Journal: BMC health services research 20110101
Title: Beyond THC: The New Generation of Cannabinoid Designer Drugs.
Journal: Frontiers in behavioral neuroscience 20110101
Title: Endocannabinoid system and psychiatry: in search of a neurobiological basis for detrimental and potential therapeutic effects.
Journal: Frontiers in behavioral neuroscience 20110101
Title: Cannabinoid CB1 and Dopamine D1 Receptors Partnership in the Modulation of Emotional Neural Processing.
Journal: Frontiers in behavioral neuroscience 20110101
Title: Cannabinoid CB1 receptor activation mediates the opposing effects of amphetamine on impulsive action and impulsive choice.
Journal: PloS one 20110101
Title: Role of centralized review processes for making reimbursement decisions on new health technologies in Europe.
Journal: ClinicoEconomics and outcomes research : CEOR 20110101
Title: Cost-effectiveness of pharmacotherapy to reduce obesity.
Journal: PloS one 20110101
Title: Acute overactive endocannabinoid signaling induces glucose intolerance, hepatic steatosis, and novel cannabinoid receptor 1 responsive genes.
Journal: PloS one 20110101
Title: Effect of the Cannabinoid Receptor-1 antagonist SR141716A on human adipocyte inflammatory profile and differentiation.
Journal: Journal of inflammation (London, England) 20110101
Title: Nicotine dependence and psychological distress: outcomes and clinical implications in smoking cessation.
Journal: Psychology research and behavior management 20110101
Title: Endocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibition.
Journal: PloS one 20110101
Title: Obesity in arabic-speaking countries.
Journal: Journal of obesity 20110101
Title: Resistance to diet-induced adiposity in cannabinoid receptor-1 deficient mice is not due to impaired adipocyte function.
Journal: Nutrition & metabolism 20110101
Title: Palatability as an addictive trigger in obesity: a changing paradigm in the past decades.
Journal: Frontiers in psychiatry 20110101
Title: Acute myocardial ischemia enhances the vanilloid TRPV1 and serotonin 5-HT3 receptor-mediated Bezold-Jarisch reflex in rats.
Journal: Pharmacological reports : PR 20110101
Title: Natural products and body weight control.
Journal: North American journal of medical sciences 20110101
Title: Therapeutic prospects of metabolically active brown adipose tissue in humans.
Journal: Frontiers in endocrinology 20110101
Title: Systemic cannabinoids produce CB₁-mediated antinociception by activation of descending serotonergic pathways that act upon spinal 5-HT(7) and 5-HT(2A) receptors.
Journal: European journal of pharmacology 20101215
Title: Termination of the CRESCENDO trial.
Journal: Lancet (London, England) 20101211
Title: Termination of the CRESCENDO trial.
Journal: Lancet (London, England) 20101211
Title: The effects of cannabinoid drugs on abnormal involuntary movements in dyskinetic and non-dyskinetic 6-hydroxydopamine lesioned rats.
Journal: Brain research 20101202
Title: Reversal of inflammation-induced impairment of glucose uptake in adipocytes by direct effect of CB1 antagonism on adipose tissue macrophages.
Journal: Obesity (Silver Spring, Md.) 20101201
Title: Cardiovascular co-medication among users of antiobesity drugs: a population-based study.
Journal: Pharmacy world & science : PWS 20101201
Title: Antagonism of ∆⁹-THC induced behavioral effects by rimonabant: time course studies in rats.
Journal: European journal of pharmacology 20101201
Title: Synthesis and biological evaluation of new N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as cannabinoid receptor ligands.
Journal: European journal of medicinal chemistry 20101201
Title: Energetic metabolism and human sperm motility: impact of CB₁ receptor activation.
Journal: Endocrinology 20101201
Title: Cannabinoid receptor activation leads to massive mobilization of myeloid-derived suppressor cells with potent immunosuppressive properties.
Journal: European journal of immunology 20101201
Title: Identification of amino-tadalafil and rimonabant in electronic cigarette products using high pressure liquid chromatography with diode array and tandem mass spectrometric detection.
Journal: Journal of chromatography. A 20101126
Title: [Rimonabant is associated with serious neuropsychiatric side effects].
Journal: Praxis 20101117
Title: Effect of the cannabinoid receptor-1 antagonist rimonabant on lipolysis in rats.
Journal: European journal of pharmacology 20101110
Title: Effects of acute low-dose combined treatment with rimonabant and sibutramine on appetite and weight gain in rats.
Journal: Pharmacology, biochemistry, and behavior 20101101
Title: Effect of non-statin lipid lowering and anti-obesity drugs on LDL subfractions in patients with mixed dyslipidaemia.
Journal: Current vascular pharmacology 20101101
Title: Pharmacological evaluation of the natural constituent of Cannabis sativa, cannabichromene and its modulation by Δ(9)-tetrahydrocannabinol.
Journal: Drug and alcohol dependence 20101101
Title: The incretin pathway as a new therapeutic target for obesity.
Journal: Maturitas 20101101
Title: Tuberoinfundibular peptide of 39 residues (TIP39) signaling modulates acute and tonic nociception.
Journal: Experimental neurology 20101101
Title: The novel cannabinoid CB1 antagonist AM6545 suppresses food intake and food-reinforced behavior.
Journal: Pharmacology, biochemistry, and behavior 20101101
Title: Chronic treatment with the cannabinoid 1 antagonist rimonabant altered vasoactive cyclo-oxygenase-derived products on arteries from obese Zucker rats.
Journal: Journal of cardiovascular pharmacology 20101101
Title: Cannabinoid receptor stimulation impairs mitochondrial biogenesis in mouse white adipose tissue, muscle, and liver: the role of eNOS, p38 MAPK, and AMPK pathways.
Journal: Diabetes 20101101
Title: Peripheral endocannabinoid system-mediated actions of rimonabant on growth hormone secretion are ghrelin-dependent.
Journal: Journal of neuroendocrinology 20101101
Title: Cannabinoids reveal separate controls for whisking amplitude and timing in rats.
Journal: Journal of neurophysiology 20101101
Title: Human platelets express authentic CB₁ and CB₂ receptors.
Journal: Current neurovascular research 20101101
Title: Rimonabant inhibits TNF-α-induced endothelial IL-6 secretion via CB1 receptor and cAMP-dependent protein kinase pathway.
Journal: Acta pharmacologica Sinica 20101101
Title: Central cannabinoid receptors modulate acquisition of eyeblink conditioning.
Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20101101
Title: Prevention: Neuropsychiatric adverse effects signal the end of the line for rimonabant.
Journal: Nature reviews. Cardiology 20101101
Title: Synthesis and biological evaluation of bivalent ligands for the cannabinoid 1 receptor.
Journal: Journal of medicinal chemistry 20101014
Title: Novel 1',1'-chain substituted hexahydrocannabinols: 9β-hydroxy-3-(1-hexyl-cyclobut-1-yl)-hexahydrocannabinol (AM2389) a highly potent cannabinoid receptor 1 (CB1) agonist.
Journal: Journal of medicinal chemistry 20101014
Title: Combination of fenofibrate with non-statin drug regimens.
Journal: Current pharmaceutical design 20101001
Title: Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism.
Journal: Nature neuroscience 20101001
Title: Relapse prevention in UK Stop Smoking Services: current practice, systematic reviews of effectiveness and cost-effectiveness analysis.
Journal: Health technology assessment (Winchester, England) 20101001
Title: Identification and hit-to-lead optimization of a novel class of CB1 antagonists.
Journal: Bioorganic & medicinal chemistry letters 20100915
Title: Regulation of subthalamic neuron activity by endocannabinoids.
Journal: Synapse (New York, N.Y.) 20100901
Title: Reduced neural response to reward following 7 days treatment with the cannabinoid CB1 antagonist rimonabant in healthy volunteers.
Journal: The international journal of neuropsychopharmacology 20100901
Title: Endocannabinoid-mediated synaptically evoked suppression of GABAergic transmission in the cerebellar cortex.
Journal: Neuroscience 20100901
Title: Genetic deletion of fatty acid amide hydrolase alters emotional behavior and serotonergic transmission in the dorsal raphe, prefrontal cortex, and hippocampus.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100901
Title: Discovery of 2-(4-((1H-1,2,4-triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2-chlorophenyl)-1H-pyrazol-3-yl)-5-tert-butyl-1,3,4-thiadiazole (GCC2680) as a potent, selective and orally efficacious cannabinoid-1 receptor antagonist.
Journal: Bioorganic & medicinal chemistry 20100901
Title: Regional enhancement of cannabinoid CB₁ receptor desensitization in female adolescent rats following repeated Delta-tetrahydrocannabinol exposure.
Journal: British journal of pharmacology 20100901
Title: GPR55-dependent and -independent ion signalling in response to lysophosphatidylinositol in endothelial cells.
Journal: British journal of pharmacology 20100901
Title: Cannabinoid receptors as target for treatment of osteoporosis: a tale of two therapies.
Journal: Current neuropharmacology 20100901
Title: Investigations on the 4-quinolone-3-carboxylic acid motif. 3. Synthesis, structure-affinity relationships, and pharmacological characterization of 6-substituted 4-quinolone-3-carboxamides as highly selective cannabinoid-2 receptor ligands.
Journal: Journal of medicinal chemistry 20100826
Title: Rimonabant: obituary for a wonder drug.
Journal: Lancet (London, England) 20100814
Title: Rimonabant for prevention of cardiovascular events (CRESCENDO): a randomised, multicentre, placebo-controlled trial.
Journal: Lancet (London, England) 20100814
Title: CB1 cannabinoid receptor expression is regulated by glucose and feeding in rat pancreatic islets.
Journal: Regulatory peptides 20100809
Title: Rimonabant is a dual inhibitor of acyl CoA:cholesterol acyltransferases 1 and 2.
Journal: Biochemical and biophysical research communications 20100806
Title: Rehashing endocannabinoid antagonists: can we selectively target the periphery to safely treat obesity and type 2 diabetes?
Journal: The Journal of clinical investigation 20100802
Title: Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity.
Journal: The Journal of clinical investigation 20100802
Title: Endocannabinoids, FOXO and the metabolic syndrome: redox, function and tipping point--the view from two systems.
Journal: Immunobiology 20100801
Title: Drug reimbursement and GPs' prescribing decisions: a randomized case-vignette study about the pharmacotherapy of obesity associated with type 2 diabetes: how GPs react to drug reimbursement.
Journal: Fundamental & clinical pharmacology 20100801
Title: Efficacy and safety of anti-obesity drugs in children and adolescents: systematic review and meta-analysis.
Journal: Obesity reviews : an official journal of the International Association for the Study of Obesity 20100801
Title: Δ⁹-Tetrahydrocannabivarin suppresses in vitro epileptiform and in vivo seizure activity in adult rats.
Journal: Epilepsia 20100801
Title: Depression-like phenotype following chronic CB1 receptor antagonism.
Journal: Neurobiology of disease 20100801
Title: Rimonabant-induced apoptosis in leukemia cell lines: activation of caspase-dependent and -independent pathways.
Journal: Biochemical pharmacology 20100801
Title: The endocannabinoid system tonically regulates inhibitory transmission and depresses the effect of ethanol in central amygdala.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100801
Title: Rimonabant-mediated changes in intestinal lipid metabolism and improved renal vascular dysfunction in the JCR:LA-cp rat model of prediabetic metabolic syndrome.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20100801
Title: Rational design of a novel peripherally-restricted, orally active CB(1) cannabinoid antagonist containing a 2,3-diarylpyrrole motif.
Journal: Bioorganic & medicinal chemistry letters 20100801
Title: Effects of in vitro antagonism of endocannabinoid-1 receptors on the glucose transport system in normal and insulin-resistant rat skeletal muscle.
Journal: Diabetes, obesity & metabolism 20100801
Title: A systematic review of the effectiveness of smoking relapse prevention interventions for abstinent smokers.
Journal: Addiction (Abingdon, England) 20100801
Title: [Current trends of nicotine dependence].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20100801
Title: Economic evaluation of lifestyle interventions for preventing diabetes and cardiovascular diseases.
Journal: International journal of environmental research and public health 20100801
Title: 1-(3,5-Diethyl-1H-pyrazol-1-yl)-3-phenyl-isoquinoline.
Journal: Acta crystallographica. Section E, Structure reports online 20100801
Title: Effects of cannabinoids on capsaicin receptor activity following exposure of primary sensory neurons to inflammatory mediators.
Journal: Life sciences 20100731
Title: Rimonabant, a cannabinoid CB1 receptor antagonist, attenuates mechanical allodynia and counteracts oxidative stress and nerve growth factor deficit in diabetic mice.
Journal: European journal of pharmacology 20100710
Title: Effect of rimonabant, the cannabinoid CB1 receptor antagonist, on peripheral nerve in streptozotocin-induced diabetic rat.
Journal: European journal of pharmacology 20100710
Title: Differential effects of CB(1) neutral antagonists and inverse agonists on gastrointestinal motility in mice.
Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20100701
Title: CB(1) modulation of hormone secretion, neuronal activation and mRNA expression following extracellular volume expansion.
Journal: Experimental neurology 20100701
Title: TrkB agonist antibody dose-dependently raises blood pressure in mice with diet-induced obesity.
Journal: American journal of hypertension 20100701
Title: Modulation of the endocannabinoid system: neuroprotection or neurotoxicity?
Journal: Experimental neurology 20100701
Title: FAAH-/- mice display differential tolerance, dependence, and cannabinoid receptor adaptation after delta 9-tetrahydrocannabinol and anandamide administration.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100701
Title: CB1 receptor inhibition leads to decreased vascular AT1 receptor expression, inhibition of oxidative stress and improved endothelial function.
Journal: Basic research in cardiology 20100701
Title: Rimonabant-induced Delta9-tetrahydrocannabinol withdrawal in rhesus monkeys: discriminative stimulus effects and other withdrawal signs.
Journal: The Journal of pharmacology and experimental therapeutics 20100701
Title: Regulation of inflammatory pain by inhibition of fatty acid amide hydrolase.
Journal: The Journal of pharmacology and experimental therapeutics 20100701
Title: The effects of the mGluR5 receptor antagonist 6-methyl-2-(phenylethynyl)-pyridine (MPEP) on behavioural responses to nicotine.
Journal: Psychopharmacology 20100701
Title: Altered architecture and functional consequences of the mesolimbic dopamine system in cannabis dependence.
Journal: Addiction biology 20100701
Title: Additive actions of the cannabinoid and neuropeptide Y systems on adiposity and lipid oxidation.
Journal: Diabetes, obesity & metabolism 20100701
Title: Therapeutic approaches to epileptogenesis--hope on the horizon.
Journal: Epilepsia 20100701
Title: CB1 receptor antagonism impairs the induction of epileptiform activity by group I metabotropic glutamate receptor activation.
Journal: Epilepsia 20100701
Title: The effect of the cannabinoid-receptor antagonist, SR141716, on the early stage of kainate-induced epileptogenesis in the adult rat.
Journal: Epilepsia 20100701
Title: The role of peripheral cannabinoid receptors type 1 in rats with visceral hypersensitivity induced by chronic restraint stress.
Journal: Journal of neurogastroenterology and motility 20100701
Title: Quantification of rimonabant (SR 141716A) in monkey plasma using HPLC with UV detection.
Journal: Journal of chromatographic science 20100701
Title: The novel triple monoamine reuptake inhibitor tesofensine induces sustained weight loss and improves glycemic control in the diet-induced obese rat: comparison to sibutramine and rimonabant.
Journal: European journal of pharmacology 20100625
Title: Chronic constriction injury reduces cannabinoid receptor 1 activity in the rostral anterior cingulate cortex of mice.
Journal: Brain research 20100621
Title: Falcarinol is a covalent cannabinoid CB1 receptor antagonist and induces pro-allergic effects in skin.
Journal: Biochemical pharmacology 20100615
Title: Antinociceptive effects of racemic AM1241 and its chirally synthesized enantiomers: lack of dependence upon opioid receptor activation.
Journal: The AAPS journal 20100601
Title: GPR55 ligands promote receptor coupling to multiple signalling pathways.
Journal: British journal of pharmacology 20100601
Title: Enhanced cognitive performance of dopamine D3 receptor 'knock-out' mice in the step-through passive-avoidance test: assessing the role of the endocannabinoid/endovanilloid systems.
Journal: Pharmacological research 20100601
Title: Cannabinoid 1 receptors modulate intestinal sensory and motor function in rat.
Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20100601
Title: Rimonabant during early pregnancy.
Journal: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20100601
Title: Direct and indirect effects of cannabinoids on in vitro GABA release in the rat arcuate nucleus.
Journal: Journal of neuroendocrinology 20100601
Title: AM 251 differentially effects food-maintained responding depending on food palatability.
Journal: Pharmacology, biochemistry, and behavior 20100601
Title: Kappa opioid mediation of cannabinoid effects of the potent hallucinogen, salvinorin A, in rodents.
Journal: Psychopharmacology 20100601
Title: How inverse can a neutral antagonist be? Strategic questions after the rimonabant issue.
Journal: Drug discovery today 20100601
Title: Diabesity: therapeutic options.
Journal: Diabetes, obesity & metabolism 20100601
Title: Pharmacological and non-pharmacological treatment of non-alcoholic fatty liver disease.
Journal: International journal of clinical practice 20100601
Title: Evidence for both inverse agonism at the cannabinoid CB1 receptor and the lack of an endogenous cannabinoid tone in the rat and guinea-pig isolated ileum myenteric plexus-longitudinal muscle preparation.
Journal: British journal of pharmacology 20100601
Title: CB1 cannabinoid receptors promote oxidative/nitrosative stress, inflammation and cell death in a murine nephropathy model.
Journal: British journal of pharmacology 20100601
Title: Cannabinoid-1 receptor activation induces reactive oxygen species-dependent and -independent mitogen-activated protein kinase activation and cell death in human coronary artery endothelial cells.
Journal: British journal of pharmacology 20100601
Title: Endocannabinoid modulation of hyperaemia evoked by physiologically relevant stimuli in the rat primary somatosensory cortex.
Journal: British journal of pharmacology 20100601
Title: Neuroprotective potential of CB1 receptor agonists in an in vitro model of Huntington's disease.
Journal: British journal of pharmacology 20100601
Title: The peptide hemopressin acts through CB1 cannabinoid receptors to reduce food intake in rats and mice.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100526
Title: Anxiety-like effects of SR141716-precipitated delta9-tetrahydrocannabinol withdrawal in mice in the elevated plus-maze.
Journal: Neuroscience letters 20100521
Title: Effects of cannabinoid receptor antagonists on maintenance and reinstatement of methamphetamine self-administration in rhesus monkeys.
Journal: European journal of pharmacology 20100510
Title: Intra-accumbens rimonabant is rewarding but induces aversion to cocaine in cocaine-treated rats, as does in vivo accumbal cannabinoid CB1 receptor silencing: critical role for glutamate receptors.
Journal: Neuroscience 20100505
Title: Effects of intra-basolateral amygdala administration of rimonabant on nociceptive behaviour and neuronal activity in the presence or absence of contextual fear.
Journal: European journal of pain (London, England) 20100501
Title: Effects of rimonabant, as monotherapy and in combination with fenofibrate or ezetimibe, on plasma adipokine levels: a pilot study.
Journal: Angiology 20100501
Title: A role for 2-arachidonoylglycerol and endocannabinoid signaling in the locomotor response to novelty induced by olfactory bulbectomy.
Journal: Pharmacological research 20100501
Title: A common polymorphism in the cannabinoid receptor 1 (CNR1) gene is associated with antipsychotic-induced weight gain in Schizophrenia.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100501
Title: Mass spectrometry screening reveals widespread diversity in trichome specialized metabolites of tomato chromosomal substitution lines.
Journal: The Plant journal : for cell and molecular biology 20100501
Title: Endocannabinoid control of gastric sensorimotor function in man.
Journal: Alimentary pharmacology & therapeutics 20100501
Title: Reduction in endocannabinoid tone is a homeostatic mechanism for specific inhibitory synapses.
Journal: Nature neuroscience 20100501
Title: Probing the cannabinoid CB1/CB2 receptor subtype selectivity limits of 1,2-diarylimidazole-4-carboxamides by fine-tuning their 5-substitution pattern.
Journal: Bioorganic & medicinal chemistry letters 20100501
Title: The role of adiponectin in the pathogenesis and treatment of non-alcoholic fatty liver disease.
Journal: Diabetes, obesity & metabolism 20100501
Title: Gestational diabetes mellitus and obesity.
Journal: Diabetes care 20100501
Title: [Therapeutical use of the cannabinoids in psychiatry].
Journal: Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20100501
Title: Neural encoding of psychomotor activation in the nucleus accumbens core, but not the shell, requires cannabinoid receptor signaling.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100407
Title: WIN55,212-2 induced deficits in spatial learning are mediated by cholinergic hypofunction.
Journal: Behavioural brain research 20100402
Title: A metabolically stable analogue of anandamide, Met-F-AEA, inhibits human thyroid carcinoma cell lines by activation of apoptosis.
Journal: Investigational new drugs 20100401
Title: A case study of ex ante, value-based price and reimbursement decision-making: TLV and rimonabant in Sweden.
Journal: The European journal of health economics : HEPAC : health economics in prevention and care 20100401
Title: Unravelling the complex dissociation of [(3)H]-rimonabant from plated CB(1) cannabinoid receptor-expressing cells.
Journal: Fundamental & clinical pharmacology 20100401
Title: The prostacyclin analog beraprost sodium ameliorates characteristics of metabolic syndrome in obese Zucker (fatty) rats.
Journal: Diabetes 20100401
Title: Cannabinoid receptor 1 blockade ameliorates albuminuria in experimental diabetic nephropathy.
Journal: Diabetes 20100401
Title: Hormone and pharmaceutical regulation of ASP production in 3T3-L1 adipocytes.
Journal: Journal of cellular biochemistry 20100401
Title: Resistance to epinephrine and hypersensitivity (hyperresponsiveness) to CB1 antagonists in a patient with pseudohypoparathyroidism type Ic.
Journal: European journal of endocrinology 20100401
Title: Cannabinoid inhibition of macrophage migration to the trans-activating (Tat) protein of HIV-1 is linked to the CB(2) cannabinoid receptor.
Journal: The Journal of pharmacology and experimental therapeutics 20100401
Title: CB1 antagonism exerts specific molecular effects on visceral and subcutaneous fat and reverses liver steatosis in diet-induced obese mice.
Journal: Diabetes 20100401
Title: Dopaminergic augmentation of delta-9-tetrahydrocannabinol (THC) discrimination: possible involvement of D(2)-induced formation of anandamide.
Journal: Psychopharmacology 20100401
Title: Pharmacological characterization of cannabinoid receptor activity in the rat-isolated ileum myenteric plexus-longitudinal muscle preparation.
Journal: British journal of pharmacology 20100401
Title: The antinociceptive effect of acetylsalicylic acid is differently affected by a CB1 agonist or antagonist and involves the serotonergic system in rats.
Journal: Life sciences 20100327
Title: Effect of rimonabant and metformin on glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 in obese women with polycystic ovary syndrome.
Journal: Clinical endocrinology 20100301
Title: CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes.
Journal: Cardiovascular research 20100301
Title: Effect of rimonabant on glycemic control in insulin-treated type 2 diabetes: the ARPEGGIO trial.
Journal: Diabetes care 20100301
Title: Use of psychotropic drugs and analgesics among users of antiobesity drugs--a population based study.
Journal: Pharmacoepidemiology and drug safety 20100301
Title: Central and peripheral consequences of the chronic blockade of CB1 cannabinoid receptor with rimonabant or taranabant.
Journal: Journal of neurochemistry 20100301
Title: FAAH deficiency promotes energy storage and enhances the motivation for food.
Journal: International journal of obesity (2005) 20100301
Title: Peripherally acting CB1-receptor antagonist: the relative importance of central and peripheral CB1 receptors in adiposity control.
Journal: International journal of obesity (2005) 20100301
Title: Discovery of benzhydrylpiperazine derivatives as CB1 receptor inverse agonists via privileged structure-based approach.
Journal: European journal of medicinal chemistry 20100301
Title: Anandamide potentiation of miniature spontaneous excitatory synaptic transmission is mediated via IP3 pathway.
Journal: Neurochemistry international 20100301
Title: Blockade of the cannabinoid CB1 receptor and alcohol dependence: preclinical evidence and preliminary clinical data.
Journal: CNS & neurological disorders drug targets 20100301
Title: Potential antipsychotic properties of central cannabinoid (CB1) receptor antagonists.
Journal: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20100301
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20100301
Title: Cannabinoid 1 receptor blockade reduces atherosclerosis with enhances reverse cholesterol transport.
Journal: Journal of atherosclerosis and thrombosis 20100226
Title: Sibutramine & naloxone: infra-additive interaction in the regulation of appetite?
Journal: Behavioural brain research 20100211
Title: Aspirin-triggered lipoxin induces CB1-dependent catalepsy in mice.
Journal: Neuroscience letters 20100205
Title: Metabolic responses to long-term pharmacological inhibition of CB1-receptor activity in mice in relation to dietary fat composition.
Journal: International journal of obesity (2005) 20100201
Title: Expression and function of endocannabinoid receptors in the human adrenal cortex.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20100201
Title: Effect of adolescent exposure to WIN 55212-2 on the acquisition and reinstatement of MDMA-induced conditioned place preference.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20100201
Title: Cannabinoid type 1 receptor blockade induces transdifferentiation towards a brown fat phenotype in white adipocytes.
Journal: Diabetes, obesity & metabolism 20100201
Title: Reduced expression of glutamate receptors and phosphorylation of CREB are responsible for in vivo Delta9-THC exposure-impaired hippocampal synaptic plasticity.
Journal: Journal of neurochemistry 20100201
Title: Regulation of MAP kinase-directed mitogenic and protein kinase B-mediated signaling by cannabinoid receptor type 1 in skeletal muscle cells.
Journal: Diabetes 20100201
Title: Human sperm anatomy: ultrastructural localization of the cannabinoid1 receptor and a potential role of anandamide in sperm survival and acrosome reaction.
Journal: Anatomical record (Hoboken, N.J. : 2007) 20100201
Title: Synthesis and structure-activity relationship of 1,2,4-triazole-containing diarylpyrazolyl carboxamide as CB1 cannabinoid receptor-ligand.
Journal: Bioorganic & medicinal chemistry 20100201
Title: Rimonabant (SR141716) induces metabolism and acquisition of fertilizing ability in human sperm.
Journal: British journal of pharmacology 20100201
Title: Cue-conditioned alcohol seeking in rats following abstinence: involvement of metabotropic glutamate 5 receptors.
Journal: British journal of pharmacology 20100201
Title: Obesity and preclinical changes of cardiac geometry and function.
Journal: Korean circulation journal 20100201
Title: Current treatment options in smoking cessation.
Journal: Hospital practice (1995) 20100201
Title: Doppel and PrPC co-immunoprecipitate in detergent-resistant membrane domains of epithelial FRT cells.
Journal: The Biochemical journal 20100115
Title: Novel thioamide derivatives as neutral CB1 receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20100115
Title: Conversion of 4-cyanomethyl-pyrazole-3-carboxamides into CB1 antagonists with lowered propensity to pass the blood-brain-barrier.
Journal: Bioorganic & medicinal chemistry letters 20100115
Title: Antinociceptive effect of the cannabinoid agonist, WIN 55,212-2, in the orofacial and temporomandibular formalin tests.
Journal: European journal of pain (London, England) 20100101
Title: Two opposite effects of Delta(9)-tetrahydrocannabinol on subthalamic nucleus neuron activity: involvement of GABAergic and glutamatergic neurotransmission.
Journal: Synapse (New York, N.Y.) 20100101
Title: Discriminative stimulus functions of methanandamide and delta(9)-THC in rats: tests with aminoalkylindoles (WIN55,212-2 and AM678) and ethanol.
Journal: Psychopharmacology 20100101
Title: Rimonabant (SR141716) has no effect on alcohol self-administration or endocrine measures in nontreatment-seeking heavy alcohol drinkers.
Journal: Psychopharmacology 20100101
Title: Synergistic inhibition of human colon cancer cell growth by the cannabinoid CB1 receptor antagonist rimonabant and oxaliplatin.
Journal: Oncology reports 20100101
Title: Imaging and quantitation of cannabinoid CB1 receptors in human and monkey brains using (18)F-labeled inverse agonist radioligands.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100101
Title: Cannabinoid CB1 receptor facilitation of substance P release in the rat spinal cord, measured as neurokinin 1 receptor internalization.
Journal: The European journal of neuroscience 20100101
Title: Anandamide suppresses proliferation and cytokine release from primary human T-lymphocytes mainly via CB2 receptors.
Journal: PloS one 20100101
Title: Biomarkers of endocannabinoid system activation in severe obesity.
Journal: PloS one 20100101
Title: Safety and efficacy trial of adipose-tissue derived oral preparation V-6 Immunitor (V-6): results of open-label, two-month, follow-up study.
Journal: Lipids in health and disease 20100101
Title: Role of platelets in neuroinflammation: a wide-angle perspective.
Journal: Journal of neuroinflammation 20100101
Title: The cannabinoid receptor agonist WIN 55,212-2 inhibits antigen-induced plasma extravasation in guinea pig airways.
Journal: International archives of allergy and immunology 20100101
Title: Receptors and channels targeted by synthetic cannabinoid receptor agonists and antagonists.
Journal: Current medicinal chemistry 20100101
Title: THC Prevents MDMA Neurotoxicity in Mice.
Journal: PloS one 20100101
Title: Weight loss in individuals with metabolic syndrome given DASH diet counseling when provided a low sodium vegetable juice: a randomized controlled trial.
Journal: Nutrition journal 20100101
Title: The multiple functions of the endocannabinoid system: a focus on the regulation of food intake.
Journal: Diabetology & metabolic syndrome 20100101
Title: Effect of the CB1 cannabinoid agonist WIN 55212-2 on the acquisition and reinstatement of MDMA-induced conditioned place preference in mice.
Journal: Behavioral and brain functions : BBF 20100101
Title: N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor.
Journal: BMC neuroscience 20100101
Title: Missing the forest (plot) for the trees? A critique of the systematic review in tobacco control.
Journal: BMC medical research methodology 20100101
Title: Endocannabinoids differentially modulate synaptic plasticity in rat hippocampal CA1 pyramidal neurons.
Journal: PloS one 20100101
Title: Association between repeated unpredictable chronic mild stress (UCMS) procedures with a high fat diet: a model of fluoxetine resistance in mice.
Journal: PloS one 20100101
Title: Type 2 diabetes: postprandial hyperglycemia and increased cardiovascular risk.
Journal: Vascular health and risk management 20100101
Title: [Simultaneous determination of rimonabant and orlistat illegally added in the weight-loss functional foods by high performance liquid chromatography-tandem mass spectrometry].
Journal: Se pu = Chinese journal of chromatography 20100101
Title: Endocannabinoids and their role in fatty liver disease.
Journal: Digestive diseases (Basel, Switzerland) 20100101
Title: Possible Anandamide and Palmitoylethanolamide involvement in human stroke.
Journal: Lipids in health and disease 20100101
Title: Anti-obesity effect of an isoflavone fatty acid ester on obese mice induced by high fat diet and its potential mechanism.
Journal: Lipids in health and disease 20100101
Title: Motion sickness, stress and the endocannabinoid system.
Journal: PloS one 20100101
Title: Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis.
Journal: Cell communication and signaling : CCS 20100101
Title: The early nutritional environment of mice determines the capacity for adipose tissue expansion by modulating genes of caveolae structure.
Journal: PloS one 20100101
Title: Exenatide: a new promising antidiabetic agent.
Journal: Indian journal of pharmaceutical sciences 20100101
Title: Adverse events associated with nicotine replacement therapy (NRT) for smoking cessation. A systematic review and meta-analysis of one hundred and twenty studies involving 177,390 individuals.
Journal: Tobacco induced diseases 20100101
Title: Validated stability-indicating RP-HPLC method for the determination of rimonabant in a pharmaceutical dosage form.
Journal: Journal of AOAC International 20100101
Title: The endocannabinoid system links gut microbiota to adipogenesis.
Journal: Molecular systems biology 20100101
Title: Effects of Endogenous PPAR Agonist Nitro-Oleic Acid on Metabolic Syndrome in Obese Zucker Rats.
Journal: PPAR research 20100101
Title: Impact of medical therapy on atheroma volume measured by different cardiovascular imaging modalities.
Journal: Cardiology research and practice 20100101
Title: Quantitative in vitro and in vivo pharmacological profile of CE-178253, a potent and selective cannabinoid type 1 (CB1) receptor antagonist.
Journal: BMC pharmacology 20100101
Title: Self-Reported Psychosocial Health in Obese Patients before and after Weight Loss.
Journal: Journal of obesity 20100101
Title: Fatty acid amide hydrolase in prostate cancer: association with disease severity and outcome, CB1 receptor expression and regulation by IL-4.
Journal: PloS one 20100101
Title: Selecting GLP-1 agonists in the management of type 2 diabetes: differential pharmacology and therapeutic benefits of liraglutide and exenatide.
Journal: Therapeutics and clinical risk management 20100101
Title: Hepatitis C virus induces the cannabinoid receptor 1.
Journal: PloS one 20100101
Title: Diet-induced obesity in zebrafish shares common pathophysiological pathways with mammalian obesity.
Journal: BMC physiology 20100101
Title: Effects of SR141716A on Cognitive and Depression-Related Behavior in an Animal Model of Premotor Parkinson's Disease.
Journal: Parkinson's disease 20100101
Title: A method for parallel solid-phase synthesis of iodinated analogs of the cannabinoid receptor type I (CB₁) inverse agonist rimonabant.
Journal: Methods in enzymology 20100101
Title: Abstracts of the 16th Scientific Symposium of the Austrian Pharmacological Society (APHAR). Vienna, Austria. November 25-27, 2010.
Journal: BMC pharmacology 20100101
Title: Rimonabant attenuates sensitization, cross-sensitization and cross-reinstatement of place preference induced by nicotine and ethanol.
Journal: Pharmacological reports : PR 20100101
Title: Is there evidence for a set point that regulates human body weight?
Journal: F1000 medicine reports 20100101
Title: Methamphetamine-induced dopamine-independent alterations in striatal gene expression in the 6-hydroxydopamine hemiparkinsonian rats.
Journal: PloS one 20100101
Title: Blood lipids and adipokines concentrations during a 6-month nutritional and physical activity intervention for metabolic syndrome treatment.
Journal: Lipids in health and disease 20100101
Title: Tumour Cannabinoid CB(1) receptor and phosphorylated epidermal growth factor receptor expression are additive prognostic markers for prostate cancer.
Journal: PloS one 20100101
Title: A common CNR1 (cannabinoid receptor 1) haplotype attenuates the decrease in HDL cholesterol that typically accompanies weight gain.
Journal: PloS one 20100101
Title: Weight-gain in psychiatric treatment: risks, implications, and strategies for prevention and management.
Journal: Mens sana monographs 20100101
Title: Efficacy, safety and cost-effectiveness of insulin sensitizers as add-on therapy in metabolic syndrome in patients with secondary sulfonylurea failure: A comparative study.
Journal: Journal of pharmacology & pharmacotherapeutics 20100101
Title: Tackling obesity: new therapeutic agents for assisted weight loss.
Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20100101
Title: The role of lipid and carbohydrate digestive enzyme inhibitors in the management of obesity: a review of current and emerging therapeutic agents.
Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20100101
Title: Adipocytokines: The pied pipers.
Journal: Journal of pharmacology & pharmacotherapeutics 20100101
Title: Sub-chronic administration of rimonabant causes loss of antidepressive activity and decreases doublecortin immunoreactivity in the mouse hippocampus.
Journal: Neuroscience letters 20091225
Title: Central cannabinoid 1 receptor antagonist administration prevents endotoxic hypotension affecting norepinephrine release in the preoptic anterior hypothalamic area.
Journal: Shock (Augusta, Ga.) 20091201
Title: The CB1 antagonist rimonabant (SR141716) blocks cue-induced reinstatement of cocaine seeking and other context and extinction phenomena predictive of relapse.
Journal: Drug and alcohol dependence 20091201
Title: Efficacy and safety of ezetimibe plus orlistat or rimonabant in statin-intolerant nondiabetic overweight/obese patients with dyslipidemia.
Journal: Journal of cardiovascular pharmacology and therapeutics 20091201
Title: Signaling pathways from cannabinoid receptor-1 activation to inhibition of N-methyl-D-aspartic acid mediated calcium influx and neurotoxicity in dorsal root ganglion neurons.
Journal: The Journal of pharmacology and experimental therapeutics 20091201
Title: Monoacylglycerol lipase limits the duration of endocannabinoid-mediated depolarization-induced suppression of excitation in autaptic hippocampal neurons.
Journal: Molecular pharmacology 20091201
Title: Endocannabinoid signalling as an anti-inflammatory therapeutic target in atherosclerosis: does it work?
Journal: Cardiovascular research 20091201
Title: Pentacycle derivatives as cannabinoid CB1 receptor ligands.
Journal: Bioorganic & medicinal chemistry letters 20091201
Title: The cannabinoid R+ methanandamide induces IL-6 secretion by prostate cancer PC3 cells.
Journal: Journal of immunotoxicology 20091201
Title: Pharmacotherapy for obesity.
Journal: British journal of clinical pharmacology 20091201
Title: Rise in antiobesity drug prescribing for children and adolescents in the UK: a population-based study.
Journal: British journal of clinical pharmacology 20091201
Title: Regulatory challenges for new drugs to treat obesity and comorbid metabolic disorders.
Journal: British journal of clinical pharmacology 20091201
Title: Cannabinoids prevent the opposite regulation of astroglial connexin43 hemichannels and gap junction channels induced by pro-inflammatory treatments.
Journal: Journal of neurochemistry 20091201
Title: Central cannabinoid signaling mediating food intake: a pharmacological-challenge magnetic resonance imaging and functional histology study in rat.
Journal: Neuroscience 20091110
Title: Hyperlocomotion and paw tremors are two highly quantifiable signs of SR141716-precipitated withdrawal from delta9-tetrahydrocannabinol in C57BL/6 mice.
Journal: Neuroscience letters 20091106
Title: The CB(1) antagonist rimonabant is adjunctively therapeutic as well as monotherapeutic in an animal model of Parkinson's disease.
Journal: Behavioural brain research 20091105
Title: The cannabinoid CB1 receptor antagonist, rimonabant, protects against acute myocardial infarction.
Journal: Basic research in cardiology 20091101
Title: Fatty acid amide hydrolase (FAAH) knockout mice exhibit enhanced acquisition of an aversive, but not of an appetitive, Barnes maze task.
Journal: Neurobiology of learning and memory 20091101
Title: Endocannabinoid modulation of amphetamine sensitization is disrupted in a rodent model of lesion-induced dopamine dysregulation.
Journal: Synapse (New York, N.Y.) 20091101
Title: Effects of cannabinoid drugs on the reinforcing properties of food in gestationally undernourished rats.
Journal: Pharmacology, biochemistry, and behavior 20091101
Title: Prosocial effects of nicotine and ethanol in adolescent rats through partially dissociable neurobehavioral mechanisms.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20091101
Title: Evaluation of prevalent phytocannabinoids in the acetic acid model of visceral nociception.
Journal: Drug and alcohol dependence 20091101
Title: FAAH inhibitor, URB-597, promotes extinction and CB(1) antagonist, SR141716, inhibits extinction of conditioned aversion produced by naloxone-precipitated morphine withdrawal, but not extinction of conditioned preference produced by morphine in rats.
Journal: Pharmacology, biochemistry, and behavior 20091101
Title: Effects of the cannabinoid CB1 antagonist rimonabant on hepatic mitochondrial function in rats fed a high-fat diet.
Journal: American journal of physiology. Endocrinology and metabolism 20091101
Title: Cannabinoids for clinicians: the rise and fall of the cannabinoid antagonists.
Journal: European journal of endocrinology 20091101
Title: Synthesis and in vitro autoradiographic evaluation of a novel high-affinity radioiodinated ligand for imaging brain cannabinoid subtype-1 receptors.
Journal: Bioorganic & medicinal chemistry letters 20091101
Title: CB1 antagonists for obesity--what lessons have we learned from rimonabant?
Journal: Nature reviews. Endocrinology 20091101
Title: Effect of the CB(1) receptor antagonists rimonabant and AM251 on the firing rate of dorsal raphe nucleus neurons in rat brain slices.
Journal: British journal of pharmacology 20091101
Title: Hypertension and diabetes: should we treat early surrogates? What are the cons?
Journal: Diabetes care 20091101
Title: Is there evidence that oral hypoglycemic agents reduce cardiovascular morbidity/mortality? Yes.
Journal: Diabetes care 20091101
Title: Adipocytokines and insulin resistance: the possible role of lipocalin-2, retinol binding protein-4, and adiponectin.
Journal: Diabetes care 20091101
Title: Obesity in the elderly diabetic patient: is weight loss beneficial? No.
Journal: Diabetes care 20091101
Title: Involvement of adipokines in rimonabant-mediated insulin sensitivity in ob/ob mice.
Journal: The Journal of pharmacy and pharmacology 20091101
Title: Characterization of the endocannabinoid system in human neuronal cells and proteomic analysis of anandamide-induced apoptosis.
Journal: The Journal of biological chemistry 20091023
Title: Atypical responsiveness of the orphan receptor GPR55 to cannabinoid ligands.
Journal: The Journal of biological chemistry 20091023
Title: A method for parallel solid-phase synthesis of iodinated analogues of the CB1 receptor inverse agonist rimonabant.
Journal: Organic letters 20091015
Title: The endocannabinoid system: potential for reducing cardiometabolic risk.
Journal: Obesity (Silver Spring, Md.) 20091001
Title: Short-term dynamics and metabolic impact of abdominal fat depots after bariatric surgery.
Journal: Diabetes care 20091001
Title: The CB1 antagonist rimonabant decreases insulin hypersecretion in rat pancreatic islets.
Journal: Obesity (Silver Spring, Md.) 20091001
Title: Sex and cannabinoid CB1 genotype differentiate palatable food and cocaine self-administration behaviors in mice.
Journal: Behavioural pharmacology 20091001
Title: Rimonabant for the treatment of overweight and obese people.
Journal: Health technology assessment (Winchester, England) 20091001
Title: Cannabinoid 1 receptor activation inhibits transient receptor potential vanilloid type 1 receptor-mediated cationic influx into rat cultured primary sensory neurons.
Journal: Neuroscience 20090915
Title: Bioisosteric replacement of the hydrazide pharmacophore of the cannabinoid-1 receptor antagonist SR141716A. Part I: potent, orally-active 1,4-disubstituted imidazoles.
Journal: Bioorganic & medicinal chemistry letters 20090915
Title: Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)-Methanandamide and JWH-015: involvement of CB2.
Journal: British journal of cancer 20090915
Title: Effects of rimonabant on the reinstatement of nicotine-conditioned place preference by drug priming in rats.
Journal: Behavioural brain research 20090914
Title: Cannabinoid regulation of nitric oxide synthase I (nNOS) in neuronal cells.
Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20090901
Title: Cannabinoid receptor 1 signalling dampens activity and mitochondrial transport in networks of enteric neurones.
Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20090901
Title: Pre-exposure to environmental cues predictive of food availability elicits hypothalamic-pituitary-adrenal axis activation and increases operant responding for food in female rats.
Journal: Addiction biology 20090901
Title: Discontinuation due to adverse events in randomized trials of orlistat, sibutramine and rimonabant: a meta-analysis.
Journal: Obesity reviews : an official journal of the International Association for the Study of Obesity 20090901
Title: Rimonabant inhibits human colon cancer cell growth and reduces the formation of precancerous lesions in the mouse colon.
Journal: International journal of cancer 20090901
Title: Inhibition of fatty acid amide hydrolase reduces reinstatement of nicotine seeking but not break point for nicotine self-administration--comparison with CB(1) receptor blockade.
Journal: Psychopharmacology 20090901
Title: Investigation of endocannabinoid modulation of conditioned responding evoked by a nicotine CS and the Pavlovian stimulus effects of CP 55,940 in adult male rats.
Journal: Psychopharmacology 20090901
Title: The use of iontophoresis in the administration of nicotine and new non-nicotine drugs through the skin for smoking cessation.
Journal: Current drug discovery technologies 20090901
Title: Age-dependent effects of the cannabinoid CB1 antagonist SR141716A on food intake, body weight change, and pruritus in rats.
Journal: Psychopharmacology 20090901
Title: Cannabinoid-1 receptor inverse agonists: current understanding of mechanism of action and unanswered questions.
Journal: International journal of obesity (2005) 20090901
Title: Adiposopathy and bariatric surgery: is 'sick fat' a surgical disease?
Journal: International journal of clinical practice 20090901
Title: Rimonabant induces partial seizures in a patient with a history of generalized epilepsy.
Journal: Epilepsia 20090901
Title: The 6th Annual World Congress on the insulin resistance syndrome.
Journal: Diabetes care 20090901
Title: Beneficial effect of a chronic treatment with rimonabant on pancreatic function and beta-cell morphology in Zucker Fatty rats.
Journal: European journal of pharmacology 20090815
Title: Substituted pyrimidines as cannabinoid CB1 receptor ligands.
Journal: Bioorganic & medicinal chemistry letters 20090815
Title: Spinal endocannabinoids and CB1 receptors mediate C-fiber-induced heterosynaptic pain sensitization.
Journal: Science (New York, N.Y.) 20090807
Title: Antagonism of the cannabinoid CB-1 receptor protects rat liver against ischaemia-reperfusion injury complicated by endotoxaemia.
Journal: Gut 20090801
Title: Blood, adipose tissue and brain levels of the cannabinoid ligands WIN-55,212 and SR-141716A after their intraperitoneal injection in mice: compound-specific and area-specific distribution within the brain.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20090801
Title: Hippocampal CB(1) receptors mediate the memory impairing effects of Delta(9)-tetrahydrocannabinol.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090801
Title: Food intake-independent effects of CB1 antagonism on glucose and lipid metabolism.
Journal: Obesity (Silver Spring, Md.) 20090801
Title: Depolarizing GABAergic synaptic input triggers endocannabinoid-mediated retrograde synaptic signaling.
Journal: Synapse (New York, N.Y.) 20090801
Title: Acute effects of morphine on distinct forms of impulsive behavior in rats.
Journal: Psychopharmacology 20090801
Title: CB1 receptor-independent actions of SR141716 on G-protein signaling: coapplication with the mu-opioid agonist Tyr-D-Ala-Gly-(NMe)Phe-Gly-ol unmasks novel, pertussis toxin-insensitive opioid signaling in mu-opioid receptor-Chinese hamster ovary cells.
Journal: The Journal of pharmacology and experimental therapeutics 20090801
Title: Discriminative stimulus properties of delta9-tetrahydrocannabinol (THC) in C57Bl/6J mice.
Journal: European journal of pharmacology 20090801
Title: Smoking cessation pharmacotherapy.
Journal: Therapeutic advances in cardiovascular disease 20090801
Title: Discovery and functional evaluation of diverse novel human CB(1) receptor ligands.
Journal: Bioorganic & medicinal chemistry letters 20090801
Title: Endocannabinoids, sperm biology and human fertility.
Journal: Pharmacological research 20090801
Title: Synthesis, cannabinoid receptor affinity, molecular modeling studies and in vivo pharmacological evaluation of new substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides. 2. Effect of the 3-carboxamide substituent on the affinity and selectivity profile.
Journal: Bioorganic & medicinal chemistry 20090801
Title: 1-(3,5-Dimethyl-1H-pyrazol-1-yl)-3-phenyl-isoquinoline.
Journal: Acta crystallographica. Section E, Structure reports online 20090801
Title: Chemical and biological investigation of cyclopropyl containing diaryl-pyrazole-3-carboxamides as novel and potent cannabinoid type 1 receptor antagonists.
Journal: Journal of medicinal chemistry 20090723
Title: Discovery of 2-[5-(4-chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydro-imidazol-4-thione (BPR-890) via an active metabolite. A novel, potent and selective cannabinoid-1 receptor inverse agonist with high antiobesity efficacy in DIO mice.
Journal: Journal of medicinal chemistry 20090723
Title: Long-term effects of weight-reducing drugs in hypertensive patients.
Journal: The Cochrane database of systematic reviews 20090708
Title: Cannabinoid type 1 receptor antagonism delays ascites formation in rats with cirrhosis.
Journal: Gastroenterology 20090701
Title: Effect of antiobesity medications in patients with type 2 diabetes mellitus.
Journal: Diabetes, obesity & metabolism 20090701
Title: CNR1 gene is associated with high neuroticism and low agreeableness and interacts with recent negative life events to predict current depressive symptoms.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090701
Title: The future of endocannabinoid-oriented clinical research after CB1 antagonists.
Journal: Psychopharmacology 20090701
Title: Acute administration of the cannabinoid CB1 antagonist rimonabant impairs positive affective memory in healthy volunteers.
Journal: Psychopharmacology 20090701
Title: Single application of a CB1 receptor antagonist rapidly following head injury prevents long-term hyperexcitability in a rat model.
Journal: Epilepsy research 20090701
Title: Hit-to-lead optimization of pyrrolo[1,2-a]quinoxalines as novel cannabinoid type 1 receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20090701
Title: Tesofensine--a novel potent weight loss medicine. Evaluation of: Astrup A, Breum L, Jensen TJ, Kroustrup JP, Larsen TM. Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese patients: a randomised, double-blind, placebo-controlled trial. Lancet 2008;372:1906-13.
Journal: Expert opinion on investigational drugs 20090701
Title: Effects of chronic treatment with the CB1 antagonist, rimonabant on the blood pressure, and vascular reactivity of obese Zucker rats.
Journal: Obesity (Silver Spring, Md.) 20090701
Title: End of the line for cannabinoid receptor 1 as an anti-obesity target? An opinion.
Journal: Nature reviews. Drug discovery 20090701
Title: Rimonabant may induce atrial fibrillation.
Journal: BMJ (Clinical research ed.) 20090612
Title: Modulation of anxiety by acute blockade and genetic deletion of the CB(1) cannabinoid receptor in mice together with biogenic amine changes in the forebrain.
Journal: Behavioural brain research 20090608
Title: Effects of cannabinoid CB1 receptor antagonist rimonabant in consolidation and reconsolidation of methamphetamine reward memory in mice.
Journal: Psychopharmacology 20090601
Title: Depolarization-induced release of endocannabinoids by murine dorsal motor nucleus of the vagus nerve neurons differentially regulates inhibitory and excitatory neurotransmission.
Journal: Neuropharmacology 20090601
Title: Rimonabant prevents additional accumulation of visceral and subcutaneous fat during high-fat feeding in dogs.
Journal: American journal of physiology. Endocrinology and metabolism 20090601
Title: Inhibitors of endocannabinoid-metabolizing enzymes reduce precipitated withdrawal responses in THC-dependent mice.
Journal: The AAPS journal 20090601
Title: Synthetic delta-9-tetrahydrocannabinol (dronabinol) can improve the symptoms of schizophrenia.
Journal: Journal of clinical psychopharmacology 20090601
Title: New therapeutic agents for diabetes mellitus: implications for anesthetic management.
Journal: Anesthesia and analgesia 20090601
Title: The endocannabinoid system: a new pharmacological target for obesity treatment?
Journal: Neuroscience bulletin 20090601
Title: Involvement of hypothalamic peptides in the anorectic action of the CB receptor antagonist rimonabant (SR 141716).
Journal: The European journal of neuroscience 20090601
Title: [Current and future medical drugs for smoking cessation].
Journal: Laryngo- rhino- otologie 20090601
Title: The psychiatric side-effects of rimonabant.
Journal: Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20090601
Title: Effects of the cannabinoid receptor ligands on anxiety-related effects of d-amphetamine and nicotine in the mouse elevated plus maze test.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20090601
Title: Discovery of 2-(2-chlorophenyl)-3-(4-chlorophenyl)-7-(2,2-difluoropropyl)-6,7-dihydro-2H-pyrazolo[3,4-f][1,4]oxazepin-8(5H)-one (PF-514273), a novel, bicyclic lactam-based cannabinoid-1 receptor antagonist for the treatment of obesity.
Journal: Journal of medicinal chemistry 20090514
Title: The structure of Rimonabant in the solid state and in solution: an experimental and theoretical study.
Journal: European journal of medicinal chemistry 20090501
Title: Attenuation of basal and cocaine-enhanced locomotion and nucleus accumbens dopamine in cannabinoid CB1-receptor-knockout mice.
Journal: Psychopharmacology 20090501
Title: Cannabinoid CB1 and cholecystokinin CCK2 receptors modulate, in an opposing way, electrically evoked [3H]GABA efflux from rat cerebral cortex cell cultures: possible relevance for cortical GABA transmission and anxiety.
Journal: The Journal of pharmacology and experimental therapeutics 20090501
Title: Changes in symptoms of depression with weight loss: results of a randomized trial.
Journal: Obesity (Silver Spring, Md.) 20090501
Title: Cannabinoid receptor-1 blockade attenuates acute pancreatitis in obesity by an adiponectin mediated mechanism.
Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20090501
Title: Development and validation of a high-performance liquid chromatographic method for bioanalytical application with rimonabant.
Journal: Journal of pharmaceutical and biomedical analysis 20090501
Title: Hair growth stimulator property of thienyl substituted pyrazole carboxamide derivatives as a CB1 receptor antagonist with in vivo antiobesity effect.
Journal: Bioorganic & medicinal chemistry letters 20090501
Title: Attrition from randomized controlled trials of pharmacological weight loss agents: a systematic review and analysis.
Journal: Obesity reviews : an official journal of the International Association for the Study of Obesity 20090501
Title: Neurobiology and systems physiology of the endocannabinoid system.
Journal: Pharmacopsychiatry 20090501
Title: [2008: the end of rimonabant's story].
Journal: Annales pharmaceutiques francaises 20090501
Title: Opioid, cannabinoid CB1 and NOP receptors do not mediate APAP-induced hypothermia in rats.
Journal: Pharmacology, biochemistry, and behavior 20090501
Title: Rimonabant affects cyclosporine a, but not tacrolimus pharmacokinetics in renal transplant recipients.
Journal: Transplantation 20090427
Title: The FAAH inhibitor URB-597 interferes with cisplatin- and nicotine-induced vomiting in the Suncus murinus (house musk shrew).
Journal: Physiology & behavior 20090420
Title: CB1 cannabinoid receptor participates in the vascular hyporeactivity resulting from hemorrhagic shock in rats.
Journal: Chinese medical journal 20090420
Title: Synthesis and structure-activity relationship of novel diarylpyrazole imide analogues as CB1 cannabinoid receptor ligands.
Journal: Bioorganic & medicinal chemistry 20090415
Title: A role for the endocannabinoid system in the increased motivation for cocaine in extended-access conditions.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090415
Title: Nonlinear turnover models for systems with physiological limits.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090411
Title: Synthesis and evaluation of dibenzothiazepines: a novel class of selective cannabinoid-1 receptor inverse agonists.
Journal: Journal of medicinal chemistry 20090409
Title: Discriminative stimulus functions in rats of AM1346, a high-affinity CB1R selective anandamide analog.
Journal: Psychopharmacology 20090401
Title: Apparent affinity estimates of rimonabant in combination with anandamide and chemical analogs of anandamide in rhesus monkeys discriminating Delta9-tetrahydrocannabinol.
Journal: Psychopharmacology 20090401
Title: Effects of sibutramine and rimonabant in rats trained to discriminate between 22- and 2-h food deprivation.
Journal: Psychopharmacology 20090401
Title: Anandamide-induced behavioral disruption through a vanilloid-dependent mechanism in rats.
Journal: Psychopharmacology 20090401
Title: Cannabinoid type 1 receptors in human skeletal muscle cells participate in the negative crosstalk between fat and muscle.
Journal: Diabetologia 20090401
Title: Synergy between enzyme inhibitors of fatty acid amide hydrolase and cyclooxygenase in visceral nociception.
Journal: The Journal of pharmacology and experimental therapeutics 20090401
Title: Adiponectin is required to mediate rimonabant-induced improvement of insulin sensitivity but not body weight loss in diet-induced obese mice.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090401
Title: Oxadiazole-diarylpyrazole 4-carboxamides as cannabinoid CB1 receptor ligands.
Journal: Bioorganic & medicinal chemistry letters 20090401
Title: Cannabinoid CB1 receptor antagonists as potential pharmacotherapies for drug abuse disorders.
Journal: International review of psychiatry (Abingdon, England) 20090401
Title: Rimonabant: marketing authorization suspended... at last: withdrawal. Half-measures.
Journal: Prescrire international 20090401
Title: Impairments in endocannabinoid signaling and depressive illness.
Journal: JAMA 20090318
Title: Localization and phenotypic characterization of brainstem neurons activated by rimonabant and WIN55,212-2.
Journal: Brain research bulletin 20090316
Title: [Effects of central endocannabinoid system on visceral hyposensitivity induced by rapid eye movement sleep deprivation: experiment with rats].
Journal: Zhonghua yi xue za zhi 20090303
Title: CB(1) and CB(2) cannabinoid receptors mediate different aspects of delta-9-tetrahydrocannabinol (THC)-induced T helper cell shift following immune activation by Legionella pneumophila infection.
Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20090301
Title: Endocannabinoids mediate acute fear adaptation via glutamatergic neurons independently of corticotropin-releasing hormone signaling.
Journal: Genes, brain, and behavior 20090301
Title: Effect of rimonabant on the high-triglyceride/ low-HDL-cholesterol dyslipidemia, intraabdominal adiposity, and liver fat: the ADAGIO-Lipids trial.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20090301
Title: CB1 receptor knockout mice are hyporesponsive to the behavior-stimulating actions of d-amphetamine: role of mGlu5 receptors.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20090301
Title: Sleep deprivation increases oleoylethanolamide in human cerebrospinal fluid.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20090301
Title: ADAGIO-Lipids gives promises but faces the setbacks.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20090301
Title: Cannabinoid receptor antagonists: pharmacological opportunities, clinical experience, and translational prognosis.
Journal: Expert opinion on emerging drugs 20090301
Title: Emerging drugs for obesity therapy.
Journal: Arquivos brasileiros de endocrinologia e metabologia 20090301
Title: A CB(2) receptor agonist, A-836339, modulates wide dynamic range neuronal activity in neuropathic rats: contributions of spinal and peripheral CB(2) receptors.
Journal: Neuroscience 20090218
Title: CB1 receptors mediate the analgesic effects of cannabinoids on colorectal distension-induced visceral pain in rodents.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090204
Title: Analogs of JHU75528, a PET ligand for imaging of cerebral cannabinoid receptors (CB1): development of ligands with optimized lipophilicity and binding affinity.
Journal: European journal of medicinal chemistry 20090201
Title: Rimonabant: a rapidly expanding role in the management of metabolic and systemic disorders besides polycystic ovarian syndrome.
Journal: Clinical endocrinology 20090201
Title: An algorithm for tailoring pharmacotherapy for smoking cessation: results from a Delphi panel of international experts.
Journal: Tobacco control 20090201
Title: Adiponectin normalization: a clue to the anti-metabolic syndrome action of rimonabant.
Journal: Drug discovery today 20090201
Title: Blockade of the endocannabinoid system for the reduction of cardiometabolic risk factors.
Journal: Obesity (Silver Spring, Md.) 20090201
Title: The effects of rimonabant on brown adipose tissue in rat: implications for energy expenditure.
Journal: Obesity (Silver Spring, Md.) 20090201
Title: 1,2,3-Triazole derivatives as new cannabinoid CB1 receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20090201
Title: Synthesis and characterization of a peripherally restricted CB1 cannabinoid antagonist, URB447, that reduces feeding and body-weight gain in mice.
Journal: Bioorganic & medicinal chemistry letters 20090201
Title: Current pharmacotherapeutic concepts for the treatment of obesity in adults.
Journal: Therapeutic advances in cardiovascular disease 20090201
Title: A randomized controlled trial of adding the nicotine patch to rimonabant for smoking cessation: efficacy, safety and weight gain.
Journal: Addiction (Abingdon, England) 20090201
Title: Trial comes too late as psychiatric side effects end hope for rimonabant.
Journal: Addiction (Abingdon, England) 20090201
Title: [Action mechanisms of anti-obesity drugs].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20090201
Title: The endocannabinoid system: a promising target for the management of type 2 diabetes.
Journal: Current protein & peptide science 20090201
Title: The role of the endocannabinoid system in lipogenesis and fatty acid metabolism.
Journal: Best practice & research. Clinical endocrinology & metabolism 20090201
Title: Use of cannabinoid CB1 receptor antagonists for the treatment of metabolic disorders.
Journal: Best practice & research. Clinical endocrinology & metabolism 20090201
Title: Central side-effects of therapies based on CB1 cannabinoid receptor agonists and antagonists: focus on anxiety and depression.
Journal: Best practice & research. Clinical endocrinology & metabolism 20090201
Title: Rimonabant: depression and suicide.
Journal: Prescrire international 20090201
Title: The endocannabinoid system and cardiometabolic risk: effects of CB1 receptor blockade on lipid metabolism.
Journal: International journal of cardiology 20090124
Title: Discovery of 1-[9-(4-chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic acid amide hydrochloride (CP-945,598), a novel, potent, and selective cannabinoid type 1 receptor antagonist.
Journal: Journal of medicinal chemistry 20090122
Title: Interventions for preventing weight gain after smoking cessation.
Journal: The Cochrane database of systematic reviews 20090121
Title: Rimonabant ameliorates insulin resistance via both adiponectin-dependent and adiponectin-independent pathways.
Journal: The Journal of biological chemistry 20090116
Title: Glucocorticoids regulate glutamate and GABA synapse-specific retrograde transmission via divergent nongenomic signaling pathways.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090114
Title: [Pharmacovigilance and teratovigilance 2008].
Journal: Revue medicale suisse 20090114
Title: Non-opioid antinociception produced by brain stem injections of improgan: significance of local, but not cross-regional, cannabinoid mechanisms.
Journal: Brain research 20090109
Title: [Nutrition-obesity. Rimonabant and cardiovascular risk factors].
Journal: Revue medicale suisse 20090107
Title: Activated endocannabinoid system in coronary artery disease and antiinflammatory effects of cannabinoid 1 receptor blockade on macrophages.
Journal: Circulation 20090106
Title: Delta 9-tetrahydrocannabinol suppresses vomiting behavior and Fos expression in both acute and delayed phases of cisplatin-induced emesis in the least shrew.
Journal: Behavioural brain research 20090103
Title: Rimonabant induced anorexia in rodents is not mediated by vagal or sympathetic gut afferents.
Journal: Neuroscience letters 20090102
Title: Functional interactions between endocannabinoid and CCK neurotransmitter systems may be critical for extinction learning.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090101
Title: Oral bioavailability of the novel cannabinoid CB1 antagonist AM6527: effects on food-reinforced behavior and comparisons with AM4113.
Journal: Pharmacology, biochemistry, and behavior 20090101
Title: A critical review of the cannabinoid receptor as a drug target for obesity management.
Journal: Obesity reviews : an official journal of the International Association for the Study of Obesity 20090101
Title: Effects of acute low-dose combined treatment with naloxone and AM 251 on food intake, feeding behaviour and weight gain in rats.
Journal: Pharmacology, biochemistry, and behavior 20090101
Title: Rimonabant, a selective cannabinoid CB1 receptor antagonist, inhibits atherosclerosis in LDL receptor-deficient mice.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20090101
Title: Characterization of a cannabinoid CB2 receptor-selective agonist, A-836339 [2,2,3,3-tetramethyl-cyclopropanecarboxylic acid [3-(2-methoxy-ethyl)-4,5-dimethyl-3H-thiazol-(2Z)-ylidene]-amide], using in vitro pharmacological assays, in vivo pain models, and pharmacological magnetic resonance imaging.
Journal: The Journal of pharmacology and experimental therapeutics 20090101
Title: Divergent effects of anandamide transporter inhibitors with different target selectivity on social play behavior in adolescent rats.
Journal: The Journal of pharmacology and experimental therapeutics 20090101
Title: Diarylimidazolyl oxadiazole and thiadiazole derivatives as cannabinoid CB1 receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20090101
Title: Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects.
Journal: Nature chemical biology 20090101
Title: Cannabinoid-1 (CB1) receptors regulate colonic propulsion by acting at motor neurons within the ascending motor pathways in mouse colon.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20090101
Title: Effect of delta9-tetrahydrocannabinol, a cannabinoid receptor agonist, on the triggering of transient lower oesophageal sphincter relaxations in dogs and humans.
Journal: British journal of pharmacology 20090101
Title: Post-ischemic brain damage: the endocannabinoid system in the mechanisms of neuronal death.
Journal: The FEBS journal 20090101
Title: Cannabinoid CB1 receptor antagonists for atherosclerosis and cardiometabolic disorders: new hopes, old concerns?
Journal: Arteriosclerosis, thrombosis, and vascular biology 20090101
Title: Antiaversive effects of cannabinoids: is the periaqueductal gray involved?
Journal: Neural plasticity 20090101
Title: Metformin maintains the weight loss and metabolic benefits following rimonabant treatment in obese women with polycystic ovary syndrome (PCOS).
Journal: Clinical endocrinology 20090101
Title: Recent advances in obesity pharmacotherapy.
Journal: Current clinical pharmacology 20090101
Title: Chronic mild stress (CMS) in mice: of anhedonia, 'anomalous anxiolysis' and activity.
Journal: PloS one 20090101
Title: Pleiotropic effects of rimonabant: clinical implications.
Journal: Current pharmaceutical design 20090101
Title: Withdrawal of Rimonabant--walking the tightrope of 21st century pharmaceutical regulation?
Journal: Current drug safety 20090101
Title: Effect of blockage of the endocannabinoid system by CB(1) antagonism on cardiovascular risk.
Journal: Pharmacological reports : PR 20090101
Title: [From a crisis to another...Pharmaceutical industry--economics].
Journal: Revue medicale de Liege 20090101
Title: Obesity, the endocannabinoid system, and bias arising from pharmaceutical sponsorship.
Journal: PloS one 20090101
Title: Lifestyle-induced metabolic inflexibility and accelerated ageing syndrome: insulin resistance, friend or foe?
Journal: Nutrition & metabolism 20090101
Title: PPAR and liver injury in HIV-infected patients.
Journal: PPAR research 20090101
Title: Rimonabant: an antagonist drug of the endocannabinoid system for the treatment of obesity.
Journal: Pharmacological reports : PR 20090101
Title: The use of sibutramine in the management of obesity and related disorders: an update.
Journal: Vascular health and risk management 20090101
Title: [Drug treatment of obesity].
Journal: Revue medicale de Bruxelles 20090101
Title: Cannabinoid receptor activation reverses kainate-induced synchronized population burst firing in rat hippocampus.
Journal: Frontiers in integrative neuroscience 20090101
Title: The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration.
Journal: BMJ (Clinical research ed.) 20090101
Title: Role of the endocannabinoid system in abdominal obesity and the implications for cardiovascular risk.
Journal: Cardiology 20090101
Title: Cannabinoid receptor CB1 antagonists state of the art and challenges.
Journal: Vitamins and hormones 20090101
Title: Endocannabinoid system and fear conditioning.
Journal: Vitamins and hormones 20090101
Title: Endocannabinoid system: An overview of its potential in current medical practice.
Journal: Neuro endocrinology letters 20090101
Title: Missing data in randomized clinical trials for weight loss: scope of the problem, state of the field, and performance of statistical methods.
Journal: PloS one 20090101
Title: The current status and future perspectives of studies of cannabinoid receptor 1 antagonists as anti-obesity agents.
Journal: Current topics in medicinal chemistry 20090101
Title: Polymorphisms of serotonin receptor 2A and 2C genes and COMT in relation to obesity and type 2 diabetes.
Journal: PloS one 20090101
Title: Endothelial dysfunction and specific inflammation in obesity hypoventilation syndrome.
Journal: PloS one 20090101
Title: The potential for automated question answering in the context of genomic medicine: an assessment of existing resources and properties of answers.
Journal: BMC bioinformatics 20090101
Title: Drugs associated with more suicidal ideations are also associated with more suicide attempts.
Journal: PloS one 20090101
Title: Systematic review and meta-analysis on the adverse events of rimonabant treatment: considerations for its potential use in hepatology.
Journal: BMC gastroenterology 20090101
Title: The endocanabinnoid system and diabetes - critical analyses of studies conducted with rimonabant.
Journal: Diabetology & metabolic syndrome 20090101
Title: Melancholic features related to rimonabant.
Journal: General hospital psychiatry 20090101
Title: Comparison of rimonabant and sibutramine treatment effects on food compulsion in rats.
Journal: Acta cirurgica brasileira 20090101
Title: [Adipose tissue inflammation and atherosclerosis].
Journal: Kardiologiia 20090101
Title: The combination of selective inhibition of the cannabinoid CB1 receptor and activation of the cannabinoid CB2 receptor yields improved attenuation of motor and autonomic deficits in a mouse model of spinal cord injury.
Journal: Clinical neurosurgery 20090101
Title: Is there an effective therapy available for non-alcoholic fatty liver disease?
Journal: F1000 medicine reports 20090101
Title: Drug addiction.
Journal: Current topics in behavioral neurosciences 20090101
Title: Feeding disorders and obesity.
Journal: Current topics in behavioral neurosciences 20090101
Title: The potential for automated question answering in the context of genomic medicine: An assessment of existing resources and properties of answers.
Journal: Summit on translational bioinformatics 20090101
Title: Cannabinoid CB1 receptor inhibition decreases vascular smooth muscle migration and proliferation.
Journal: Biochemical and biophysical research communications 20081226
Title: Endogenous fatty acid ethanolamides suppress nicotine-induced activation of mesolimbic dopamine neurons through nuclear receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20081217
Title: Rational design, synthesis and biological evaluation of new 1,5-diarylpyrazole derivatives as CB1 receptor antagonists, structurally related to rimonabant.
Journal: European journal of medicinal chemistry 20081201
Title: A comparison between rimonabant and metformin in reducing biochemical hyperandrogenaemia and insulin resistance in patients with polycystic ovary syndrome (PCOS): a randomized open-label parallel study.
Journal: Clinical endocrinology 20081201
Title: Smoking and suicide: a brief overview.
Journal: Drug and alcohol dependence 20081201
Title: Exploring the binding features of rimonabant analogues and acyclic CB1 antagonists: docking studies and QSAR analysis.
Journal: Journal of molecular modeling 20081201
Title: Facilitation of contextual fear memory extinction and anti-anxiogenic effects of AM404 and cannabidiol in conditioned rats.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20081201
Title: Antipsychotic-induced alterations in CB1 receptor-mediated G-protein signaling and in vivo pharmacology in rats.
Journal: Neuropharmacology 20081201
Title: The cannabinoid CB1 receptor antagonist rimonabant stimulates 2-deoxyglucose uptake in skeletal muscle cells by regulating the expression of phosphatidylinositol-3-kinase.
Journal: Molecular pharmacology 20081201
Title: Virodhamine relaxes the human pulmonary artery through the endothelial cannabinoid receptor and indirectly through a COX product.
Journal: British journal of pharmacology 20081201
Title: Auditory gating in rat hippocampus and medial prefrontal cortex: effect of the cannabinoid agonist WIN55,212-2.
Journal: Neuropharmacology 20081201
Title: CB(1) receptor antagonism: biological basis for metabolic effects.
Journal: Drug discovery today 20081201
Title: Dietary treatment for obesity.
Journal: Nature clinical practice. Gastroenterology & hepatology 20081201
Title: Brain TRPV1: a depressing TR(i)P down memory lane?
Journal: Trends in pharmacological sciences 20081201
Title: Cost-effectiveness of pharmacological anti-obesity treatments: a systematic review.
Journal: International journal of obesity (2005) 20081201
Title: Differential response to a selective cannabinoid receptor antagonist (SR141716: rimonabant) in female mice from lines selectively bred for high voluntary wheel-running behaviour.
Journal: Behavioural pharmacology 20081201
Title: End of the line for cannabinoid receptor 1 as an anti-obesity target?
Journal: Nature reviews. Drug discovery 20081201
Title: High on habits.
Journal: Frontiers in neuroscience 20081201
Title: General medical with depression drugs associated.
Journal: Psychiatry (Edgmont (Pa. : Township)) 20081201
Title: Biarylpyrazolyl oxadiazole as potent, selective, orally bioavailable cannabinoid-1 receptor antagonists for the treatment of obesity.
Journal: Journal of medicinal chemistry 20081127
Title: Reciprocal influences of CB1 cannabinoid receptor agonists on ERK and JNK signalling in N1E-115 cells.
Journal: FEBS letters 20081126
Title: The cannabinoid CB1 receptor inverse agonist AM 251 and antagonist AM 4113 produce similar effects on the behavioral satiety sequence in rats.
Journal: Behavioural brain research 20081121
Title: Delta-9-tetrahydrocannabinol differently affects striatal c-Fos expression following haloperidol or clozapine administration.
Journal: European journal of pharmacology 20081119
Title: The anandamide membrane transporter inhibitor, VDM-11, modulates sleep and c-Fos expression in the rat brain.
Journal: Neuroscience 20081111
Title: Constitutive activity at the cannabinoid CB1 receptor is required for behavioral response to noxious chemical stimulation of TRPV1: antinociceptive actions of CB1 inverse agonists.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20081105
Title: Blockade of THC-seeking behavior and relapse in monkeys by the cannabinoid CB(1)-receptor antagonist rimonabant.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20081101
Title: Enhancement of endocannabinoid neurotransmission through CB1 cannabinoid receptors counteracts the reinforcing and psychostimulant effects of cocaine.
Journal: The international journal of neuropsychopharmacology 20081101
Title: Inhibitory effect of salvinorin A, from Salvia divinorum, on ileitis-induced hypermotility: cross-talk between kappa-opioid and cannabinoid CB(1) receptors.
Journal: British journal of pharmacology 20081101
Title: Intrinsic effects of AM4113, a putative neutral CB1 receptor selective antagonist, on open-field behaviors in rats.
Journal: Pharmacology, biochemistry, and behavior 20081101
Title: Antinociceptive effects of tetrazole inhibitors of endocannabinoid inactivation: cannabinoid and non-cannabinoid receptor-mediated mechanisms.
Journal: British journal of pharmacology 20081101
Title: SERENADE: the Study Evaluating Rimonabant Efficacy in Drug-naive Diabetic Patients: effects of monotherapy with rimonabant, the first selective CB1 receptor antagonist, on glycemic control, body weight, and lipid profile in drug-naive type 2 diabetes.
Journal: Diabetes care 20081101
Title: N-arachidonyl maleimide potentiates the pharmacological and biochemical effects of the endocannabinoid 2-arachidonylglycerol through inhibition of monoacylglycerol lipase.
Journal: The Journal of pharmacology and experimental therapeutics 20081101
Title: Peripheral, but not central, CB1 antagonism provides food intake-independent metabolic benefits in diet-induced obese rats.
Journal: Diabetes 20081101
Title: Effects on food intake and blood lipids of cannabinoid receptor 1 antagonist treatment in lean rats.
Journal: Obesity (Silver Spring, Md.) 20081101
Title: [New therapies for type 2 diabetes: what place for incretin-based agents and rimonabant compared to the previous ones?].
Journal: La Revue de medecine interne 20081101
Title: Ethanol self-administration is regulated by CB1 receptors in the nucleus accumbens and ventral tegmental area in alcohol-preferring AA rats.
Journal: Alcoholism, clinical and experimental research 20081101
Title: Acute ethanol suppresses glutamatergic neurotransmission through endocannabinoids in hippocampal neurons.
Journal: Journal of neurochemistry 20081101
Title: The cannabinoid CB1 receptor and the endocannabinoid anandamide: possible antidepressant targets.
Journal: Expert opinion on therapeutic targets 20081101
Title: Effect of rimonabant, micronised fenofibrate and their combination on cardiometabolic risk factors in overweight/obese patients: a pilot study.
Journal: Expert opinion on pharmacotherapy 20081101
Title: American College of Endocrinology Pre-Diabetes Consensus Conference: part two.
Journal: Diabetes care 20081101
Title: Current and emerging therapies in nonalcoholic fatty liver disease.
Journal: Seminars in liver disease 20081101
Title: Differential endocannabinoid regulation of extinction in appetitive and aversive Barnes maze tasks.
Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20081101
Title: The effects of medications used for the management of diabetes and obesity on postprandial lipid metabolism.
Journal: Current diabetes reviews 20081101
Title: Rimonabant for the treatment of obesity.
Journal: Recent patents on cardiovascular drug discovery 20081101
Title: Context-specific reversal of cocaine sensitization by the CB1 cannabinoid receptor antagonist rimonabant.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20081001
Title: N-arachidonylethanolamide-induced increase in aqueous humor outflow facility.
Journal: Investigative ophthalmology & visual science 20081001
Title: An endocannabinoid signaling system modulates anxiety-like behavior in male Syrian hamsters.
Journal: Psychopharmacology 20081001
Title: Lifetime body mass index and later atherosclerosis risk in young adults: examining causal links using Mendelian randomization in the Cardiovascular Risk in Young Finns study.
Journal: European heart journal 20081001
Title: Contextual renewal of nicotine seeking in rats and its suppression by the cannabinoid-1 receptor antagonist Rimonabant (SR141716A).
Journal: Neuropharmacology 20081001
Title: Prejunctional and peripheral effects of the cannabinoid CB(1) receptor inverse agonist rimonabant (SR 141716).
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20081001
Title: Play an ADAGIO with a STRADIVARIUS: the right patient for CB1 receptor antagonists?
Journal: Nature clinical practice. Cardiovascular medicine 20081001
Title: Prevention of hepatic fibrosis in a murine model of metabolic syndrome with nonalcoholic steatohepatitis.
Journal: The American journal of pathology 20081001
Title: Effects of rimonabant on behavior maintained by progressive ratio schedules of sucrose reinforcement in obese Zucker (fa/fa) rats.
Journal: Behavioural pharmacology 20081001
Title: Is rimonabant efficacious and safe in the treatment of obesity?
Journal: Expert opinion on pharmacotherapy 20081001
Title: [Sleep disorders associated with treatment with rimonabant].
Journal: Revista de neurologia 20081001
Title: Novel aspects of adipocyte-induced skeletal muscle insulin resistance.
Journal: Archives of physiology and biochemistry 20081001
Title: The endocannabinoid system: an osteopathic perspective.
Journal: The Journal of the American Osteopathic Association 20081001
Title: Recent advances in the management of type 2 diabetes mellitus: a review.
Journal: Postgraduate medical journal 20081001
Title: Effect of weight-reducing agents on glycaemic parameters and progression to Type 2 diabetes: a review.
Journal: Diabetic medicine : a journal of the British Diabetic Association 20081001
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20081001
Title: Pharmacotherapy for smoking cessation.
Journal: Therapeutic advances in respiratory disease 20081001
Title: [Association of obesity and depression].
Journal: Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20081001
Title: Endocannabinoid system and cardio-metabolic risk.
Journal: The Medical journal of Malaysia 20081001
Title: Prize sessions.
Journal: Indian journal of pharmacology 20081001
Title: Discovery and labeling of high-affinity 3,4-diarylpyrazolines as candidate radioligands for in vivo imaging of cannabinoid subtype-1 (CB1) receptors.
Journal: Journal of medicinal chemistry 20080925
Title: Synthesis, ex vivo evaluation, and radiolabeling of potent 1,5-diphenylpyrrolidin-2-one cannabinoid subtype-1 receptor ligands as candidates for in vivo imaging.
Journal: Journal of medicinal chemistry 20080925
Title: Bioisosteric replacement of the pyrazole 3-carboxamide moiety of rimonabant. A novel series of oxadiazoles as CB1 cannabinoid receptor antagonists.
Journal: Organic & biomolecular chemistry 20080921
Title: Bioisosteric replacement of the pyrazole 5-aryl moiety of N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A). A novel series of alkynylthiophenes as potent and selective cannabinoid-1 receptor antagonists.
Journal: Journal of medicinal chemistry 20080911
Title: Attenuation of cue-induced heroin-seeking behavior by cannabinoid CB1 antagonist infusions into the nucleus accumbens core and prefrontal cortex, but not basolateral amygdala.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080901
Title: Head-to-head studies evaluating efficacy of pharmaco-therapy for obesity: a systematic review and meta-analysis.
Journal: Obesity reviews : an official journal of the International Association for the Study of Obesity 20080901
Title: The effect of cannabinoid CB(1) receptor antagonist rimonabant (SR-141716) on ethanol drinking in high-preferring rats.
Journal: Alcohol (Fayetteville, N.Y.) 20080901
Title: Differential modulation of AP-1- and CRE-driven transcription by cannabinoid agonists emphasizes functional selectivity at the CB1 receptor.
Journal: British journal of pharmacology 20080901
Title: Leptin receptor deficiency is associated with upregulation of cannabinoid 1 receptors in limbic brain regions.
Journal: Synapse (New York, N.Y.) 20080901
Title: Reversal of visceral adiposity in candy-diet fed female Wistar rats by the CB1 receptor antagonist rimonabant.
Journal: International journal of obesity (2005) 20080901
Title: Depression and weight loss: opposite outcome for surgery and rimonabant?
Journal: Obesity reviews : an official journal of the International Association for the Study of Obesity 20080901
Title: Determination of rimonabant in human plasma and hair by liquid chromatography-mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080901
Title: Rimonabant and depression.
Journal: Pharmacopsychiatry 20080901
Title: Critical role of the endocannabinoid system in the regulation of food intake and energy metabolism, with phylogenetic, developmental, and pathophysiological implications.
Journal: Endocrine, metabolic & immune disorders drug targets 20080901
Title: Role of endocannabinoids and their analogues in obesity and eating disorders.
Journal: Eating and weight disorders : EWD 20080901
Title: Investigations on the 4-quinolone-3-carboxylic acid motif. 2. Synthesis and structure-activity relationship of potent and selective cannabinoid-2 receptor agonists endowed with analgesic activity in vivo.
Journal: Journal of medicinal chemistry 20080828
Title: [CB1 receptor inhibition and glucose metabolism: role of rimonabant in type 2 diabetes].
Journal: Revue medicale suisse 20080827
Title: [Rimonabant helps in overweight patients with multiple cardiovascular risk factors such as type 2 diabetes].
Journal: Revue medicale suisse 20080827
Title: The cannabinoid CB(1) receptor antagonist CE prolongs spatial memory duration in a rat delayed radial arm maze memory task.
Journal: European journal of pharmacology 20080820
Title: The CB1 receptor antagonist, SR141716A, prevents high-frequency stimulation-induced reduction of feedback inhibition in the rat dentate gyrus following perforant path stimulation in vivo.
Journal: Brain research 20080805
Title: Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects.
Journal: Gut 20080801
Title: The endogenous cannabinoid system modulates nicotine reward and dependence.
Journal: The Journal of pharmacology and experimental therapeutics 20080801
Title: Cannabinoid type 1 receptor blockade promotes mitochondrial biogenesis through endothelial nitric oxide synthase expression in white adipocytes.
Journal: Diabetes 20080801
Title: Endocannabinoid- and mGluR5-dependent short-term synaptic depression in an isolated neuron/bouton preparation from the hippocampal CA1 region.
Journal: Journal of neurophysiology 20080801
Title: CB(1) cannabinoid receptor activation dose dependently modulates neuronal activity within caudal but not rostral song control regions of adult zebra finch telencephalon.
Journal: Psychopharmacology 20080801
Title: Genetic and pharmacological manipulations of the CB(1) receptor alter ethanol preference and dependence in ethanol preferring and nonpreferring mice.
Journal: Synapse (New York, N.Y.) 20080801
Title: The CB1 endocannabinoid system modulates adipocyte insulin sensitivity.
Journal: Obesity (Silver Spring, Md.) 20080801
Title: Novel sterically hindered cannabinoid CB1 receptor ligands.
Journal: Bioorganic & medicinal chemistry 20080801
Title: Aqueous humor outflow effects of 2-arachidonylglycerol.
Journal: Experimental eye research 20080801
Title: Endocannabinoid system in food intake and metabolic regulation.
Journal: Current opinion in lipidology 20080801
Title: Satiety signalling histaminergic system and brain-gut peptides in regulation of food intake in rats with portocaval anastomosis.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080801
Title: Cannabinoid CB(1) receptor antagonist rimonabant attenuates reinstatement of ketamine conditioned place preference in rats.
Journal: European journal of pharmacology 20080728
Title: Delta(9)-tetrahydrocannabinol prolongs the immobility time in the mouse forced swim test: involvement of cannabinoid CB(1) receptor and serotonergic system.
Journal: European journal of pharmacology 20080728
Title: Additive subthreshold dose effects of cannabinoid CB(1) receptor antagonist and selective serotonin reuptake inhibitor in antidepressant behavioral tests.
Journal: European journal of pharmacology 20080728
Title: Rimonabant and progression of atherosclerosis in obese persons.
Journal: JAMA 20080716
Title: Facile synthesis, ex-vivo and in vitro screening of 3-sulfonamide derivative of 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid piperidin-1-ylamide (SR141716) a potent CB1 receptor antagonist.
Journal: Bioorganic & medicinal chemistry letters 20080715
Title: Cannabinoid agonists differentially substitute for the discriminative stimulus effects of Delta(9)-tetrahydrocannabinol in C57BL/6J mice.
Journal: Psychopharmacology 20080701
Title: Rimonabant blocks the expression but not the development of locomotor sensitization to nicotine in rats.
Journal: Psychopharmacology 20080701
Title: Cat odour-induced anxiety--a study of the involvement of the endocannabinoid system.
Journal: Psychopharmacology 20080701
Title: Hippocampal endocannabinoids inhibit spatial learning and limit spatial memory in rats.
Journal: Psychopharmacology 20080701
Title: Endocannabinoids modulate encoding of sequential memory in the rat hippocampus.
Journal: Psychopharmacology 20080701
Title: Discriminative stimulus effects of the cannabinoid CB1 receptor antagonist rimonabant in rats.
Journal: Psychopharmacology 20080701
Title: Reply to the letter to the editor 'Long-term cannabinoid receptor (CB1) blockade in obesity: implications for the development of colorectal cancer'.
Journal: International journal of cancer 20080701
Title: Long-term effect of CB1 blockade with rimonabant on cardiometabolic risk factors: two year results from the RIO-Europe Study.
Journal: European heart journal 20080701
Title: Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat.
Journal: Psychopharmacology 20080701
Title: Cannabinoid-1 receptor antagonists reduce caloric intake by decreasing palatable diet selection in a novel dessert protocol in female rats.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20080701
Title: Rimonabant in rats with a metabolic syndrome: good news after the depression.
Journal: British journal of pharmacology 20080701
Title: Positron emission tomography imaging using an inverse agonist radioligand to assess cannabinoid CB1 receptors in rodents.
Journal: NeuroImage 20080701
Title: Cannabidiol, extracted from Cannabis sativa, selectively inhibits inflammatory hypermotility in mice.
Journal: British journal of pharmacology 20080701
Title: The cannabinoid receptor-1 antagonist rimonabant inhibits platelet activation and reduces pro-inflammatory chemokines and leukocytes in Zucker rats.
Journal: British journal of pharmacology 20080701
Title: Short- and long-term effects of cannabinoids on the extinction of contextual fear memory in rats.
Journal: Neurobiology of learning and memory 20080701
Title: Inhibitors of cannabinoid receptors and glucose metabolism.
Journal: Current opinion in clinical nutrition and metabolic care 20080701
Title: The cardiometabolic drug rimonabant: after 2 years of RIO-Europe and STRADIVARIUS.
Journal: European heart journal 20080701
Title: The discovery of taranabant, a selective cannabinoid-1 receptor inverse agonist for the treatment of obesity.
Journal: Archiv der Pharmazie 20080701
Title: Beyond insulin replacement: addressing the additional needs of the diabetes patient.
Journal: Diabetes, obesity & metabolism 20080701
Title: Approaches to treatment of pre-diabetes and obesity and promising new approaches to type 2 diabetes.
Journal: Diabetes care 20080701
Title: [Pharmacological treatment options for prevention of alcohol relapse].
Journal: Fortschritte der Neurologie-Psychiatrie 20080701
Title: The element of surprise.
Journal: Nature medicine 20080701
Title: Soothing the seizures of children.
Journal: Nature medicine 20080701
Title: Acute effects of the cannabinoid receptor agonist WIN55212-2 on dopamine release in rat: an in vivo electrochemical study.
Journal: The Chinese journal of physiology 20080630
Title: Conformationally constrained analogues of N-(piperidinyl)-5-(4-chlorophenyl)-1-(2,4- dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716): design, synthesis, computational analysis, and biological evaluations.
Journal: Journal of medicinal chemistry 20080626
Title: The cannabinoid CB1 receptor antagonist rimonabant dose-dependently inhibits memory recall in the passive avoidance task in domestic chicks (Gallus domesticus).
Journal: Brain research bulletin 20080615
Title: Enhanced striatal glutamate release after the administration of rimonabant to 6-hydroxydopamine-lesioned rats.
Journal: Neuroscience letters 20080613
Title: Endogenous opioids and cannabinoids: system interactions in the regulation of appetite, grooming and scratching.
Journal: Physiology & behavior 20080609
Title: Impaired cannabinoid receptor type 1 signaling interferes with stress-coping behavior in mice.
Journal: The pharmacogenomics journal 20080601
Title: Cannabinoid CB1 receptor antagonists attenuate cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080601
Title: Expression and function of CB1 receptor in the rat striatum: localization and effects on D1 and D2 dopamine receptor-mediated motor behaviors.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080601
Title: The cannabinoid delta-9-tetrahydrocannabinol mediates inhibition of macrophage chemotaxis to RANTES/CCL5: linkage to the CB2 receptor.
Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20080601
Title: CXCR2 chemokine receptor antagonism enhances DOP opioid receptor function via allosteric regulation of the CXCR2-DOP receptor heterodimer.
Journal: The Biochemical journal 20080601
Title: Cannabinoids inhibit network-driven synapse loss between hippocampal neurons in culture.
Journal: The Journal of pharmacology and experimental therapeutics 20080601
Title: Aminopyrazine CB1 receptor inverse agonists.
Journal: Bioorganic & medicinal chemistry letters 20080601
Title: Cannabinoid receptor 1 blocker rimonabant (SR 141716) for treatment of alcohol dependence: results from a placebo-controlled, double-blind trial.
Journal: Journal of clinical psychopharmacology 20080601
Title: The role of CB1 receptors in psychostimulant addiction.
Journal: Addiction biology 20080601
Title: Blocking cannabinoid CB1 receptors for the treatment of nicotine dependence: insights from pre-clinical and clinical studies.
Journal: Addiction biology 20080601
Title: Pharmacotherapy for obesity in menopausal women.
Journal: Menopause international 20080601
Title: Activation of endocannabinoid transmission induces antidepressant-like effects in rats.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080601
Title: Smoking cessation therapy with varenicline.
Journal: International journal of chronic obstructive pulmonary disease 20080601
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20080601
Title: Early vascular aging (EVA): consequences and prevention.
Journal: Vascular health and risk management 20080601
Title: Nutrigenomic analysis of diet-gene interactions on functional supplements for weight management.
Journal: Current genomics 20080601
Title: Locomotor effects of morphine or alcohol in mice after a repeated treatment with the cannabinoid agonist HU 210.
Journal: European journal of pharmacology 20080531
Title: [Positive influence on cardiovascular risk factor by blocking the endocannabinoid system].
Journal: Praxis 20080528
Title: Liquid chromatography tandem mass spectrometry method for the quantification of rimonabant, a CB1 receptor antagonist, in human plasma.
Journal: Biomedical chromatography : BMC 20080501
Title: Effects of rimonabant, a cannabinoid CB1 receptor ligand, on energy expenditure in lean rats.
Journal: International journal of obesity (2005) 20080501
Title: Effects of a Cannabinoid1 receptor antagonist and Serotonin2C receptor agonist alone and in combination on motivation for palatable food: a dose-addition analysis study in mice.
Journal: The Journal of pharmacology and experimental therapeutics 20080501
Title: Increased energy expenditure contributes more to the body weight-reducing effect of rimonabant than reduced food intake in candy-fed wistar rats.
Journal: Endocrinology 20080501
Title: First in vivo evidence for a functional interaction between chemokine and cannabinoid systems in the brain.
Journal: The Journal of pharmacology and experimental therapeutics 20080501
Title: The phytocannabinoid Delta(9)-tetrahydrocannabivarin modulates inhibitory neurotransmission in the cerebellum.
Journal: British journal of pharmacology 20080501
Title: CB1 receptor blockade reduces the anxiogenic-like response and ameliorates the neurochemical imbalances associated with alcohol withdrawal in rats.
Journal: Neuropharmacology 20080501
Title: Cytochrome P-450 metabolites of 2-arachidonoylglycerol play a role in Ca2+-induced relaxation of rat mesenteric arteries.
Journal: American journal of physiology. Heart and circulatory physiology 20080501
Title: Modulation of sensory neuron potassium conductances by anandamide indicates roles for metabolites.
Journal: British journal of pharmacology 20080501
Title: A saturated N-acylethanolamine other than N-palmitoyl ethanolamine with anti-inflammatory properties: a neglected story..
Journal: Journal of neuroendocrinology 20080501
Title: Endocannabinoids, blood pressure and the human heart.
Journal: Journal of neuroendocrinology 20080501
Title: Blood pressure lowering effects of rimonabant in obesity-related hypertension.
Journal: Journal of neuroendocrinology 20080501
Title: Endocannabinoids: some like it fat (and sweet too).
Journal: Journal of neuroendocrinology 20080501
Title: Dysregulation of the endocannabinoid system in obesity.
Journal: Journal of neuroendocrinology 20080501
Title: Central versus peripheral antagonism of cannabinoid CB1 receptor in obesity: effects of LH-21, a peripherally acting neutral cannabinoid receptor antagonist, in Zucker rats.
Journal: Journal of neuroendocrinology 20080501
Title: Endocannabinoids, adipose tissue and lipid metabolism.
Journal: Journal of neuroendocrinology 20080501
Title: Cannabinoid type 1 receptor: another arrow in the adipocytes' bow.
Journal: Journal of neuroendocrinology 20080501
Title: CB1 receptor blockade and its impact on cardiometabolic risk factors: overview of the RIO programme with rimonabant.
Journal: Journal of neuroendocrinology 20080501
Title: The endocannabinoid system and the control of glucose homeostasis.
Journal: Journal of neuroendocrinology 20080501
Title: The challenge of treating obesity: the endocannabinoid system as a potential target.
Journal: Journal of the American Dietetic Association 20080501
Title: [Adipocytokines: implications in the prognosis and drug treatment of cardiovascular diseases].
Journal: Revista clinica espanola 20080501
Title: Suppression by the cannabinoid CB1 receptor antagonist, rimonabant, of the reinforcing and motivational properties of a chocolate-flavoured beverage in rats.
Journal: Behavioural pharmacology 20080501
Title: [Treatment of type 2 diabetes with new oral antihyperglycaemic drugs].
Journal: MMW Fortschritte der Medizin 20080501
Title: [Rimonabant. Risk of depression has not been finally clarified].
Journal: Medizinische Monatsschrift fur Pharmazeuten 20080501
Title: Constitutive activity of the cannabinoid CB1 receptor regulates the function of co-expressed Mu opioid receptors.
Journal: The Journal of biological chemistry 20080425
Title: Identification of novel cannabinoid CB1 receptor antagonists by using virtual screening with a pharmacophore model.
Journal: Journal of medicinal chemistry 20080424
Title: Long term cannabinoid receptor (CB1) blockade in obesity: implications for the development of colorectal cancer.
Journal: International journal of cancer 20080415
Title: Conformational analysis and receptor docking of N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide (taranabant, MK-0364), a novel, acyclic cannabinoid-1 receptor inverse agonist.
Journal: Journal of medicinal chemistry 20080410
Title: Benzodioxoles: novel cannabinoid-1 receptor inverse agonists for the treatment of obesity.
Journal: Journal of medicinal chemistry 20080410
Title: Effect of rimonabant on progression of atherosclerosis in patients with abdominal obesity and coronary artery disease: the STRADIVARIUS randomized controlled trial.
Journal: JAMA 20080402
Title: The hope and fear of rimonabant.
Journal: JAMA 20080402
Title: [The endocannabinoid system].
Journal: Praxis 20080402
Title: Bidirectional cannabinoid modulation of social behavior in adolescent rats.
Journal: Psychopharmacology 20080401
Title: Design, synthesis and biological evaluation of piperazine analogues as CB1 cannabinoid receptor ligands.
Journal: Bioorganic & medicinal chemistry 20080401
Title: Inhibitory effect of the anorexic compound oleoylethanolamide on gastric emptying in control and overweight mice.
Journal: Journal of molecular medicine (Berlin, Germany) 20080401
Title: [New oral antidiabetic agents--clinical perspectives].
Journal: Der Internist 20080401
Title: Tetrazole-biarylpyrazole derivatives as cannabinoid CB1 receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20080401
Title: Update on pharmacologic options for smoking cessation treatment.
Journal: The American journal of medicine 20080401
Title: Smoking cessation 2008.
Journal: IDrugs : the investigational drugs journal 20080401
Title: Stress-induced analgesia in mice: evidence for interaction between endocannabinoids and cholecystokinin.
Journal: The European journal of neuroscience 20080401
Title: Prevention and noninvasive management of coronary atherosclerosis in patients with diabetes.
Journal: Current atherosclerosis reports 20080401
Title: Orlistat in the prevention of diabetes in the obese patient.
Journal: Vascular health and risk management 20080401
Title: Varenicline in the treatment of tobacco dependence.
Journal: Neuropsychiatric disease and treatment 20080401
Title: [Residual risk in cardiovascular prevention].
Journal: Giornale italiano di cardiologia (2006) 20080401
Title: [Dyslipidemia in visceral obesity: pathophysiological mechanisms, clinical implications and therapy].
Journal: Giornale italiano di cardiologia (2006) 20080401
Title: [Pharmacological therapy of obesity].
Journal: Giornale italiano di cardiologia (2006) 20080401
Title: Synthesis, cannabinoid receptor affinity, and molecular modeling studies of substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides.
Journal: Journal of medicinal chemistry 20080327
Title: Indol-3-yl-tetramethylcyclopropyl ketones: effects of indole ring substitution on CB2 cannabinoid receptor activity.
Journal: Journal of medicinal chemistry 20080327
Title: Some effects of CB1 antagonists with inverse agonist and neutral biochemical properties.
Journal: Physiology & behavior 20080318
Title: Pharmacotherapeutic targeting of the endocannabinoid signaling system: drugs for obesity and the metabolic syndrome.
Journal: Physiology & behavior 20080318
Title: Cannabinoid CB(1) receptor activation modulates spontaneous contractile activity in mouse ileal longitudinal muscle.
Journal: European journal of pharmacology 20080317
Title: Trimethylaluminium mediated amide bond formation in a continuous flow microreactor as key to the synthesis of rimonabant and efaproxiral.
Journal: Chemical communications (Cambridge, England) 20080307
Title: Rimonabant (SR141716) exerts anti-proliferative and immunomodulatory effects in human peripheral blood mononuclear cells.
Journal: British journal of pharmacology 20080301
Title: Alcohol inhibits spontaneous activity of basolateral amygdala projection neurons in the rat: involvement of the endocannabinoid system.
Journal: Alcoholism, clinical and experimental research 20080301
Title: The role of endocannabinoids in the regulation of gastric emptying: alterations in mice fed a high-fat diet.
Journal: British journal of pharmacology 20080301
Title: Cannabinoid receptor 2 (CB2) mediates immunoglobulin class switching from IgM to IgE in cultures of murine-purified B lymphocytes.
Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20080301
Title: Determination of endocannabinoid receptor antagonist SR141716 (rimonabant) in plasma by liquid chromatograph tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080301
Title: Oral administration of the antiobesity drugs, sibutramine and rimonabant, increases acetylcholine efflux selectively in the medial prefrontal cortex of the rat.
Journal: Molecular psychiatry 20080301
Title: Cannabinoids provoke alcoholic steatosis through a conspiracy of neighbors.
Journal: Cell metabolism 20080301
Title: Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver.
Journal: Cell metabolism 20080301
Title: Rimonabant for overweight and 'metabolic syndrome': the attempt to supersize disease and risk by pharmaceutical marketing.
Journal: Internal and emergency medicine 20080301
Title: Pharmacotherapy and psychotherapy in cannabis withdrawal and dependence.
Journal: Expert review of neurotherapeutics 20080301
Title: [Prescription of rimonabant in the early stage of pregnancy?].
Journal: Medizinische Monatsschrift fur Pharmazeuten 20080301
Title: Identification of a presynaptic cannabinoid CB1 receptor in the guinea-pig atrium and sequencing of the guinea-pig CB1 receptor.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080301
Title: [Rimonabant (Acomplia)].
Journal: Journal de pharmacie de Belgique 20080301
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20080301
Title: [The endocannabinoid system and treatment of obesity].
Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20080227
Title: Efficacy and safety of the weight-loss drug rimonabant.
Journal: Lancet (London, England) 20080216
Title: Efficacy and safety of the weight-loss drug rimonabant.
Journal: Lancet (London, England) 20080216
Title: Involvement of subthalamic nucleus in the stimulatory effect of Delta(9)-tetrahydrocannabinol on dopaminergic neurons.
Journal: Neuroscience 20080206
Title: [Metabolic syndrome: jumble syndrome of obesity or specific entity? Which treatment: diet or polypill?].
Journal: Revue medicale suisse 20080206
Title: [The endocannabinoid system as a novel target for the treatment of liver fibrosis].
Journal: Pathologie-biologie 20080201
Title: Involvement of kappa-opioid and endocannabinoid system on Salvinorin A-induced reward.
Journal: Biological psychiatry 20080201
Title: Co-administration of SR141716 with peptide YY3-36 or oxyntomodulin has additive effects on food intake in mice.
Journal: Diabetes, obesity & metabolism 20080201
Title: Cannabinoids stimulate prostaglandin production by human gestational tissues through a tissue- and CB1-receptor-specific mechanism.
Journal: American journal of physiology. Endocrinology and metabolism 20080201
Title: The cannabinoid antagonist AM251 attenuates nicotine self-administration and nicotine-seeking behaviour in rats.
Journal: Neuropharmacology 20080201
Title: Adiponectin: an update.
Journal: Diabetes & metabolism 20080201
Title: Management of type 2 diabetes in the obese patient: current concerns and emerging therapies.
Journal: Current medical research and opinion 20080201
Title: Effect of rimonabant on blood pressure in overweight/obese patients with/without co-morbidities: analysis of pooled RIO study results.
Journal: Journal of hypertension 20080201
Title: Topical WIN55212-2 alleviates intraocular hypertension in rats through a CB1 receptor mediated mechanism of action.
Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20080201
Title: Efficacy and safety of rimonabant for improvement of multiple cardiometabolic risk factors in overweight/obese patients: pooled 1-year data from the Rimonabant in Obesity (RIO) program.
Journal: Diabetes care 20080201
Title: Is weight loss beneficial for reduction of morbidity and mortality? What is the controversy about?
Journal: Diabetes care 20080201
Title: Rimonabant: new data and emerging experience.
Journal: Current atherosclerosis reports 20080201
Title: Endocannabinoid system overactivity and the metabolic syndrome: prospects for treatment.
Journal: Current diabetes reports 20080201
Title: Local administration of a cannabinoid agonist alters norepinephrine efflux in the rat frontal cortex.
Journal: Neuroscience letters 20080124
Title: Delta 9-tetrahydrocannabinol-induced catalepsy-like immobilization is mediated by decreased 5-HT neurotransmission in the nucleus accumbens due to the action of glutamate-containing neurons.
Journal: Neuroscience 20080124
Title: Obesity in adults.
Journal: BMJ clinical evidence 20080118
Title: [Pharmacovigilance update].
Journal: Revue medicale suisse 20080116
Title: The PET radioligand [11C]MePPEP binds reversibly and with high specific signal to cannabinoid CB1 receptors in nonhuman primate brain.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080101
Title: The cannabinoid CB1 receptor antagonist SR141716A (Rimonabant) enhances the metabolic benefits of long-term treatment with oleoylethanolamide in Zucker rats.
Journal: Neuropharmacology 20080101
Title: Methanandamide activation of a novel current in mouse trigeminal ganglion sensory neurons in vitro.
Journal: Neuropharmacology 20080101
Title: Regulation of hypothalamic endocannabinoid levels by neuropeptides and hormones involved in food intake and metabolism: insulin and melanocortins.
Journal: Neuropharmacology 20080101
Title: Cannabinoid receptor-mediated translocation of NO-sensitive guanylyl cyclase and production of cyclic GMP in neuronal cells.
Journal: Neuropharmacology 20080101
Title: Reduced anxiety-like behaviour induced by genetic and pharmacological inhibition of the endocannabinoid-degrading enzyme fatty acid amide hydrolase (FAAH) is mediated by CB1 receptors.
Journal: Neuropharmacology 20080101
Title: Cross-sensitization and cross-tolerance between exogenous cannabinoid antinociception and endocannabinoid-mediated stress-induced analgesia.
Journal: Neuropharmacology 20080101
Title: Type-1 cannabinoid receptors colocalize with caveolin-1 in neuronal cells.
Journal: Neuropharmacology 20080101
Title: CB1-cannabinoid receptors are involved in the modulation of non-synaptic [3H]serotonin release from the rat hippocampus.
Journal: Neurochemistry international 20080101
Title: Long-term cognitive deficits induced by a single, extremely low dose of tetrahydrocannabinol (THC): behavioral, pharmacological and biochemical studies in mice.
Journal: Pharmacology, biochemistry, and behavior 20080101
Title: Pretreatment with subeffective doses of Rimonabant attenuates orexigenic actions of orexin A-hypocretin 1.
Journal: Neuropharmacology 20080101
Title: Antidepressant-like behavioral effects of impaired cannabinoid receptor type 1 signaling coincide with exaggerated corticosterone secretion in mice.
Journal: Psychoneuroendocrinology 20080101
Title: Cannabinoid-mediated neuroprotection, not immunosuppression, may be more relevant to multiple sclerosis.
Journal: Journal of neuroimmunology 20080101
Title: [Pharmacotherapy of obesity].
Journal: Der Internist 20080101
Title: An update on therapeutics for tobacco dependence.
Journal: Expert opinion on pharmacotherapy 20080101
Title: Role of the endocannabinoid system in metabolic control.
Journal: Current opinion in nephrology and hypertension 20080101
Title: Cost-utility analysis of rimonabant in the treatment of obesity.
Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20080101
Title: Obesity: a review of pathogenesis and management strategies.
Journal: Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20080101
Title: Pharmacological regulation of dyslipoproteinaemia in insulin resistant states.
Journal: Current vascular pharmacology 20080101
Title: Role of the endocannabinoid system in energy balance regulation and obesity.
Journal: Frontiers of hormone research 20080101
Title: Emerging concepts in the medical and surgical treatment of obesity.
Journal: Frontiers of hormone research 20080101
Title: CB1 cannabinoid antagonists: structure-activity relationships and potential therapeutic applications.
Journal: Current topics in medicinal chemistry 20080101
Title: [Correct prescription of Acomplia (rimonabant) is assured by knowledge].
Journal: Lakartidningen 20080101
Title: [Medication of the month. Rimonabant (Acomplia): first CB1 receptor antagonist of the endocannabinoid system].
Journal: Revue medicale de Liege 20080101
Title: Review: orlistat, sibutramine, and rimonabant reduce weight in overweight and obese persons.
Journal: ACP journal club 20080101
Title: The orexigenic effect of ghrelin is mediated through central activation of the endogenous cannabinoid system.
Journal: PloS one 20080101
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20080101
Title: Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis.
Journal: Arthritis research & therapy 20080101
Title: Novel pharmacological approaches for treating tobacco dependence and withdrawal: current status.
Journal: Drugs 20080101
Title: Feeding induced by cannabinoids is mediated independently of the melanocortin system.
Journal: PloS one 20080101
Title: [Cannabinoid system and feeding regulation].
Journal: Adicciones 20080101
Title: Cannabinoid CB1 receptor antagonists in therapeutic and structural perspectives.
Journal: Chemical record (New York, N.Y.) 20080101
Title: STRADIVARIUS: a brave trial aimed at clarifying benefits of rimonabant therapy.
Journal: Cardiovascular journal of Africa 20080101
Title: [Buerger's disease: current concepts].
Journal: Revista portuguesa de cirurgia cardio-toracica e vascular : orgao oficial da Sociedade Portuguesa de Cirurgia Cardio-Toracica e Vascular 20080101
Title: Modification of cardiometabolic risk through cannabinoid type-1 receptor antagonism.
Journal: Angiology 20080101
Title: Neuropharmacology of human appetite expression.
Journal: Developmental disabilities research reviews 20080101
Title: [Endocannabinoid system in the brain...and elsewhere].
Journal: Revue medicale de Liege 20080101
Title: [Raising HDL cholesterol: which is the best strategy?].
Journal: Revista da Associacao Medica Brasileira (1992) 20080101
Title: [Role of cannabinoid receptors in regulation of cardiac tolerance to ischemia and reperfusion].
Journal: Izvestiia Akademii nauk. Seriia biologicheskaia 20080101
Title: Loss of cannabinoid receptor CB1 induces preterm birth.
Journal: PloS one 20080101
Title: New drugs for type 2 diabetes mellitus: what is their place in therapy?
Journal: Drugs 20080101
Title: Modeling transitions in body composition: the approach to steady state for anthropometric measures and physiological functions in the Minnesota human starvation study.
Journal: Dynamic medicine : DM 20080101
Title: Gateways to clinical trials. July-August 2008.
Journal: Methods and findings in experimental and clinical pharmacology 20080101
Title: The prince and the pauper. A tale of anticancer targeted agents.
Journal: Molecular cancer 20080101
Title: Enhancement of a modified Mediterranean-style, low glycemic load diet with specific phytochemicals improves cardiometabolic risk factors in subjects with metabolic syndrome and hypercholesterolemia in a randomized trial.
Journal: Nutrition & metabolism 20080101
Title: PPARdelta Agonism for the Treatment of Obesity and Associated Disorders: Challenges and Opportunities.
Journal: PPAR research 20080101
Title: Rimonabant improves weight and glycaemic control: first oral antidiabetic therapy in newly diagnosed type 2 diabetics.
Journal: Cardiovascular journal of Africa 20080101
Title: Activation instead of blocking mesolimbic dopaminergic reward circuitry is a preferred modality in the long term treatment of reward deficiency syndrome (RDS): a commentary.
Journal: Theoretical biology & medical modelling 20080101
Title: Lack of association of genetic variants in genes of the endocannabinoid system with anorexia nervosa.
Journal: Child and adolescent psychiatry and mental health 20080101
Title: Different transcriptional control of metabolism and extracellular matrix in visceral and subcutaneous fat of obese and rimonabant treated mice.
Journal: PloS one 20080101
Title: Obesity-related cardiometabolic complications.
Journal: Clinical cornerstone 20080101
Title: The endocannabinoid system as a target for obesity treatment.
Journal: Clinical cornerstone 20080101
Title: [New avenues for pharmacotherapy of type 2 diabetes mellitus].
Journal: Klinicheskaia meditsina 20080101
Title: CB1 cannabinoid receptor inhibition: promising approach for heart failure?
Journal: Congestive heart failure (Greenwich, Conn.) 20080101
Title: Smoking cessation in cardiovascular patients.
Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20080101
Title: New therapeutic approaches in type 2 diabetes.
Journal: Acta clinica Belgica 20080101
Title: Post-graduate CME.
Journal: Indian journal of psychiatry 20080101
Title: Psychosis following anti-obesity treatment with rimonabant.
Journal: Obesity facts 20080101
Title: Metabolic syndrome and chronic kidney disease.
Journal: Indian journal of nephrology 20080101
Title: Behaviour therapy for obesity treatment considering approved drug therapy.
Journal: GMS health technology assessment 20080101
Title: Potentiation of electrical and chemical synaptic transmission mediated by endocannabinoids.
Journal: Neuron 20071220
Title: [Still questions around the slimming agent rimobant. Not approved in USA because of the risk of mental adverse effects].
Journal: Lakartidningen 20071219
Title: Cannabinoid-1 receptor blockade in cardiometabolic risk reduction: efficacy.
Journal: The American journal of cardiology 20071217
Title: Cannabinoid-1 receptor blockade in cardiometabolic risk reduction: safety, tolerability, and therapeutic potential.
Journal: The American journal of cardiology 20071217
Title: [A meta-analysis of the efficacy and safety of the anti-obesity agent Rimonabant].
Journal: Ugeskrift for laeger 20071210
Title: Long term pharmacotherapy for obesity and overweight: updated meta-analysis.
Journal: BMJ (Clinical research ed.) 20071208
Title: Effect of cannabinoid CB1 receptor antagonist SR141716A and CB1 receptor knockout on cue-induced reinstatement of Ensure and corn-oil seeking in mice.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20071201
Title: Cannabinoid CB1 receptor stimulation affords neuroprotection in MPTP-induced neurotoxicity by attenuating S100B up-regulation in vitro.
Journal: Journal of molecular medicine (Berlin, Germany) 20071201
Title: The uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist memantine prolongs spatial memory in a rat delayed radial-arm maze memory task.
Journal: European journal of pharmacology 20071201
Title: Discovery of 1,1-dioxo-1,2,6-thiadiazine-5-carboxamide derivatives as cannabinoid-like molecules with agonist and antagonist activity.
Journal: Bioorganic & medicinal chemistry 20071201
Title: The orphan receptor GPR55 is a novel cannabinoid receptor.
Journal: British journal of pharmacology 20071201
Title: Blockade of cannabinoid CB1 receptors improves renal function, metabolic profile, and increased survival of obese Zucker rats.
Journal: Kidney international 20071201
Title: New 1,8-naphthyridine and quinoline derivatives as CB2 selective agonists.
Journal: Bioorganic & medicinal chemistry letters 20071201
Title: Functional blockage of the cannabinoid receptor type 1 evokes a kappa-opiate-dependent analgesia.
Journal: Journal of neurochemistry 20071201
Title: Increased depressor response to N-arachidonoyl-dopamine during high salt intake: role of the TRPV1 receptor.
Journal: Journal of hypertension 20071201
Title: C-terminal truncated cannabinoid receptor 1 coexpressed with G protein trimer in Sf9 cells exists in a precoupled state and shows constitutive activity.
Journal: The FEBS journal 20071201
Title: Cannabinoid-induced tolerance is associated with a CB1 receptor G protein coupling switch that is prevented by ultra-low dose rimonabant.
Journal: Behavioural pharmacology 20071201
Title: CB1 receptor-mediated control of the release of endocannabinoids (as assessed by microdialysis coupled with LC/MS) in the rat hypothalamus.
Journal: The European journal of neuroscience 20071201
Title: Cannabinoid-1 receptor antagonists in type-2 diabetes.
Journal: Best practice & research. Clinical endocrinology & metabolism 20071201
Title: Rimonabant: suicide and depression. Depression and suicidal tendencies are about twice as frequent with rimonabant as with placebo.
Journal: Prescrire international 20071201
Title: Cannabinoids in health and disease.
Journal: Dialogues in clinical neuroscience 20071201
Title: Pharmacogenetic aspects of addictive behaviors.
Journal: Dialogues in clinical neuroscience 20071201
Title: Pharmacotherapy for obesity.
Journal: Current atherosclerosis reports 20071201
Title: Role of endocannabinoids in regulating drug dependence.
Journal: Neuropsychiatric disease and treatment 20071201
Title: Endocannabinoid signaling in midbrain dopamine neurons: more than physiology?
Journal: Current neuropharmacology 20071201
Title: Diaryl dihydropyrazole-3-carboxamides with significant in vivo antiobesity activity related to CB1 receptor antagonism: synthesis, biological evaluation, and molecular modeling in the homology model.
Journal: Journal of medicinal chemistry 20071129
Title: [Antiobesity drugs--new limitations].
Journal: Revue medicale suisse 20071128
Title: [The endocannabinoid system, overweight, and the CB1-endocannabinoid-receptor antagonist rimonabant].
Journal: Nederlands tijdschrift voor geneeskunde 20071124
Title: [New drugs; rimonabant].
Journal: Nederlands tijdschrift voor geneeskunde 20071124
Title: Depression and anxiety with rimonabant.
Journal: Lancet (London, England) 20071117
Title: Efficacy and safety of the weight-loss drug rimonabant: a meta-analysis of randomised trials.
Journal: Lancet (London, England) 20071117
Title: Cannabinoid CB(2) receptor activation prevents bronchoconstriction and airway oedema in a model of gastro-oesophageal reflux.
Journal: European journal of pharmacology 20071114
Title: Cannabinoid CB(1) receptor and gastric acid secretion.
Journal: Digestive diseases and sciences 20071101
Title: Activation of cannabinoid CB1 and CB2 receptors suppresses neuropathic nociception evoked by the chemotherapeutic agent vincristine in rats.
Journal: British journal of pharmacology 20071101
Title: PSNCBAM-1, a novel allosteric antagonist at cannabinoid CB1 receptors with hypophagic effects in rats.
Journal: British journal of pharmacology 20071101
Title: Single and multiple doses of rimonabant antagonize acute effects of smoked cannabis in male cannabis users.
Journal: Psychopharmacology 20071101
Title: Grooming, scratching and feeding: role of response competition in acute anorectic response to rimonabant in male rats.
Journal: Psychopharmacology 20071101
Title: Significance of cannabinoid CB1 receptors in improgan antinociception.
Journal: The journal of pain : official journal of the American Pain Society 20071101
Title: The endogenous cannabinoid anandamide inhibits cromakalim-activated K+ currents in follicle-enclosed Xenopus oocytes.
Journal: The Journal of pharmacology and experimental therapeutics 20071101
Title: Management of obesity in patients with peripheral arterial disease.
Journal: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20071101
Title: The inhibition of monoacylglycerol lipase by URB602 showed an anti-inflammatory and anti-nociceptive effect in a murine model of acute inflammation.
Journal: British journal of pharmacology 20071101
Title: GPR55 and the vascular receptors for cannabinoids.
Journal: British journal of pharmacology 20071101
Title: Characterization of the vasorelaxant mechanisms of the endocannabinoid anandamide in rat aorta.
Journal: British journal of pharmacology 20071101
Title: Inhibition of milk ingestion and growth after administration of a neutral cannabinoid CB1 receptor antagonist on the first postnatal day in the mouse.
Journal: Pediatric research 20071101
Title: Lack of depolarization-induced suppression of inhibition (DSI) in layer 2/3 interneurons that receive cannabinoid-sensitive inhibitory inputs.
Journal: Journal of neurophysiology 20071101
Title: The genetic versus pharmacological invalidation of the cannabinoid CB(1) receptor results in differential effects on 'non-associative' memory and forebrain monoamine concentrations in mice.
Journal: Neurobiology of learning and memory 20071101
Title: Vascular pharmacology of a novel cannabinoid-like compound, 3-(5-dimethylcarbamoyl-pent-1-enyl)-N-(2-hydroxy-1-methyl-ethyl)benzamide (VSN16) in the rat.
Journal: British journal of pharmacology 20071101
Title: Inhibition of 2-arachidonoylglycerol catabolism modulates vasoconstriction of rat middle cerebral artery by the thromboxane mimetic, U-46619.
Journal: British journal of pharmacology 20071101
Title: Endocannabinoid system and cardiometabolic risk.
Journal: Clinical pharmacology and therapeutics 20071101
Title: Acute anorectic response to cannabinoid CB1 receptor antagonist/inverse agonist AM 251 in rats: indirect behavioural mediation.
Journal: Behavioural pharmacology 20071101
Title: Effects of AM1346, a high-affinity CB1 receptor selective anandamide analog, on open-field behavior in rats.
Journal: Behavioural pharmacology 20071101
Title: The effect of CB(1) receptor antagonism in the right basolateral amygdala on conditioned fear and associated analgesia in rats.
Journal: The European journal of neuroscience 20071101
Title: Rimonabant: the role of endocannabinoid type 1 receptor antagonism in modulating the weight and lipid profile of obese patients.
Journal: Current atherosclerosis reports 20071101
Title: The endocannabinoid system: novel pathway for cardiometabolic Risk-factor reduction.
Journal: JAAPA : official journal of the American Academy of Physician Assistants 20071101
Title: Cannabinoids elicit antidepressant-like behavior and activate serotonergic neurons through the medial prefrontal cortex.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20071024
Title: [Obesity: a review of currently used antiobesity drugs and new compounds in clinical development].
Journal: Postepy higieny i medycyny doswiadczalnej (Online) 20071019
Title: Cannabinoid type 1 receptor antagonists (rimonabant) for smoking cessation.
Journal: The Cochrane database of systematic reviews 20071017
Title: [Obesity in adults].
Journal: Praxis 20071017
Title: Cannabinoid receptor antagonists counteract sensorimotor gating deficits in the phencyclidine model of psychosis.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20071001
Title: Effects of SR141716 and WIN 55,212-2 on tolerance to ethanol in rats using the acute and rapid procedures.
Journal: Psychopharmacology 20071001
Title: Cortico-limbic circuitry for conditioned nicotine-seeking behavior in rats involves endocannabinoid signaling.
Journal: Psychopharmacology 20071001
Title: The endocannabinoid anandamide inhibits the function of alpha4beta2 nicotinic acetylcholine receptors.
Journal: Molecular pharmacology 20071001
Title: Rimonabant as a novel therapeutic option for nonalcoholic steatohepatitis.
Journal: Liver international : official journal of the International Association for the Study of the Liver 20071001
Title: Mediterranean diet and the metabolic syndrome.
Journal: Molecular nutrition & food research 20071001
Title: Drugs in the treatment of obesity: sibutramine, orlistat and rimonabant.
Journal: Public health nutrition 20071001
Title: Understanding cannabinoid psychoactivity with mouse genetic models.
Journal: PLoS biology 20071001
Title: Adipose tissue and diabetes therapy: do we hit the target?
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20071001
Title: [Prevention of cardiovascular disease by blocking the endocannabinoid system].
Journal: Herz 20071001
Title: Endocannabinoid regulation of matrix metalloproteinases: implications in ischemic stroke.
Journal: Cardiovascular & hematological agents in medicinal chemistry 20071001
Title: Strategies to reduce vascular risk associated with obesity.
Journal: Current vascular pharmacology 20071001
Title: Does a weight loss medicine make sense for obese type 2 diabetes? New information on endocannabinoid blockers.
Journal: Current diabetes reports 20071001
Title: Exenatide and rimonabant: new treatments that may be useful in the management of diabetes and obesity.
Journal: Current diabetes reports 20071001
Title: The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat involves the CB(2) cannabinoid receptor.
Journal: European journal of pharmacology 20070910
Title: Delayed treatment with cannabidiol has a cerebroprotective action via a cannabinoid receptor-independent myeloperoxidase-inhibiting mechanism.
Journal: Journal of neurochemistry 20070901
Title: Exposure to marijuana smoke impairs memory retrieval in mice.
Journal: The Journal of pharmacology and experimental therapeutics 20070901
Title: A call to action: new treatment options provide even more reasons to intervene in tobacco dependence.
Journal: Nature clinical practice. Cardiovascular medicine 20070901
Title: Involvement of CB1 and CB2 receptors in the modulation of cholinergic neurotransmission in mouse gastric preparations.
Journal: Pharmacological research 20070901
Title: Understanding metabolic homeostasis and imbalance: what is the role of the endocannabinoid system?
Journal: The American journal of medicine 20070901
Title: What is the potential role of cannabinoid-1 receptor blockade in glucose and lipid management?
Journal: The American journal of medicine 20070901
Title: WIN-55,212-2 chronically implanted into the CA3 region of the dorsal hippocampus impairs learning: a novel method for studying chronic, brain-area-specific effects of cannabinoids.
Journal: Behavioural pharmacology 20070901
Title: Short-term memory is modulated by the spontaneous release of endocannabinoids: evidence from hippocampal population codes.
Journal: Behavioural pharmacology 20070901
Title: The safety of obesity drugs.
Journal: Expert opinion on drug safety 20070901
Title: Rimonabant: a novel approach for the treatment of obesity and cardiometabolic risk by blockade of the endocannabinoid system.
Journal: Future cardiology 20070901
Title: Helix 8 Leu in the CB1 cannabinoid receptor contributes to selective signal transduction mechanisms.
Journal: The Journal of biological chemistry 20070824
Title: The CB1 cannabinoid receptor mediates excitotoxicity-induced neural progenitor proliferation and neurogenesis.
Journal: The Journal of biological chemistry 20070817
Title: Role of cannabinoidergic mechanisms in ethanol self-administration and ethanol seeking in rat adult offspring following perinatal exposure to Delta9-tetrahydrocannabinol.
Journal: Toxicology and applied pharmacology 20070815
Title: Emerging pharmacotherapies for smoking cessation.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070815
Title: Differences in the relative potency of SR 141716A and AM 251 as antagonists of various in vivo effects of cannabinoid agonists in C57BL/6J mice.
Journal: European journal of pharmacology 20070813
Title: Pharmacological inhibition of CB1 cannabinoid receptor protects against doxorubicin-induced cardiotoxicity.
Journal: Journal of the American College of Cardiology 20070807
Title: Endocannabinoid inhibition: a new cardioprotective strategy against doxorubicin cardiotoxicity.
Journal: Journal of the American College of Cardiology 20070807
Title: Combination of rimonabant and donepezil prolongs spatial memory duration.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070801
Title: Non-selective cation channels, transient receptor potential channels and ischemic stroke.
Journal: Biochimica et biophysica acta 20070801
Title: Regulation of PI3K/Akt/GSK-3 pathway by cannabinoids in the brain.
Journal: Journal of neurochemistry 20070801
Title: NOP receptor antagonist, JTC-801, blocks cannabinoid-evoked hypothermia in rats.
Journal: Neuropeptides 20070801
Title: The effect of the palmitoylethanolamide analogue, palmitoylallylamide (L-29) on pain behaviour in rodent models of neuropathy.
Journal: British journal of pharmacology 20070801
Title: Virodhamine and CP55,940 modulate cAMP production and IL-8 release in human bronchial epithelial cells.
Journal: British journal of pharmacology 20070801
Title: Evidence for a modulatory role of cannabinoids on the excitatory NANC neurotransmission in mouse colon.
Journal: Pharmacological research 20070801
Title: Fused-core silica column high-performance liquid chromatography/tandem mass spectrometric determination of rimonabant in mouse plasma.
Journal: Analytical chemistry 20070801
Title: Evidence for the involvement of cannabinoid CB1 receptors in the bimatoprost-induced contractions on the human isolated ciliary muscle.
Journal: Investigative ophthalmology & visual science 20070801
Title: Methoxy- and fluorine-substituted analogs of O-1302: synthesis and in vitro binding affinity for the CB1 cannabinoid receptor.
Journal: Chemical & pharmaceutical bulletin 20070801
Title: Blood pressure-lowering drugs not considered as antihypertensives.
Journal: Current hypertension reports 20070801
Title: The endocannabinoid signaling system: a potential target for next-generation therapeutics for alcoholism.
Journal: Mini reviews in medicinal chemistry 20070801
Title: Blocking the cannabinoid receptors: drug candidates and therapeutic promises.
Journal: Chemistry & biodiversity 20070801
Title: The cannabinoid CB1 receptor antagonist, rimonabant, as a promising pharmacotherapy for alcohol dependence: preclinical evidence.
Journal: Molecular neurobiology 20070801
Title: Cannabinoids in eating disorders and obesity.
Journal: Molecular neurobiology 20070801
Title: The burden of type 2 diabetes: strategies to prevent or delay onset.
Journal: Vascular health and risk management 20070801
Title: Cannabinoid CB1 receptor inverse agonists and neutral antagonists: effects on food intake, food-reinforced behavior and food aversions.
Journal: Physiology & behavior 20070724
Title: Cannabinoid type 1 receptor antagonists (rimonabant) for smoking cessation.
Journal: The Cochrane database of systematic reviews 20070718
Title: Panel advises against rimonabant approval.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070715
Title: A comparison of the effects of the CB(1) receptor antagonist SR141716A, pre-feeding and changed palatability on the microstructure of ingestive behaviour.
Journal: Psychopharmacology 20070701
Title: Effects of the cannabinoid CB1 receptor antagonist rimonabant on distinct measures of impulsive behavior in rats.
Journal: Psychopharmacology 20070701
Title: MDMA attenuates THC withdrawal syndrome in mice.
Journal: Psychopharmacology 20070701
Title: The fatty acid amide hydrolase inhibitor URB597 (cyclohexylcarbamic acid 3'-carbamoylbiphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice.
Journal: The Journal of pharmacology and experimental therapeutics 20070701
Title: The synthetic cannabinoid HU210 induces spatial memory deficits and suppresses hippocampal firing rate in rats.
Journal: British journal of pharmacology 20070701
Title: Rimonabant reduces obesity-associated hepatic steatosis and features of metabolic syndrome in obese Zucker fa/fa rats.
Journal: Hepatology (Baltimore, Md.) 20070701
Title: [New concepts in the treatment of type 2 diabetes].
Journal: Der Internist 20070701
Title: Smoking cessation: lessons learned from clinical trial evidence.
Journal: Current opinion in cardiology 20070701
Title: Involvement of the endocannabinoid system in retinal damage after high intraocular pressure-induced ischemia in rats.
Journal: Investigative ophthalmology & visual science 20070701
Title: Cannabinoids and cardiovascular disease: the outlook for clinical treatments.
Journal: Current vascular pharmacology 20070701
Title: [Cannabinoid receptor blocker rimonabant. CNS side effects prevent U.S. approval].
Journal: MMW Fortschritte der Medizin 20070628
Title: Scaffold hopping, synthesis and structure-activity relationships of 5,6-diaryl-pyrazine-2-amide derivatives: a novel series of CB1 receptor antagonists.
Journal: Bioorganic & medicinal chemistry 20070615
Title: Cannabinoids inhibit sodium-dependent, high-affinity excitatory amino acid transport in cultured rat cortical astrocytes.
Journal: Biochemical pharmacology 20070615
Title: Novel inhibitors of fatty acid amide hydrolase.
Journal: Bioorganic & medicinal chemistry letters 20070615
Title: Cannabinoid CB1 receptors in the paraventricular nucleus and central control of penile erection: immunocytochemistry, autoradiography and behavioral studies.
Journal: Neuroscience 20070615
Title: Analogs of SR-141716A (Rimonabant) alter d-amphetamine-evoked [3H] dopamine overflow from preloaded striatal slices and amphetamine-induced hyperactivity.
Journal: Life sciences 20070613
Title: Attenuation of allergic contact dermatitis through the endocannabinoid system.
Journal: Science (New York, N.Y.) 20070608
Title: Improgan-induced hypothermia: a role for cannabinoid receptors in improgan-induced changes in nociceptive threshold and body temperature.
Journal: Brain research 20070604
Title: The cannabinoid antagonist SR 141716A (Rimonabant) reduces the increase of extra-cellular dopamine release in the rat nucleus accumbens induced by a novel high palatable food.
Journal: Neuroscience letters 20070604
Title: Rimonabant: just an antiobesity drug? Current evidence on its pleiotropic effects.
Journal: Molecular pharmacology 20070601
Title: Nicotinic facilitation of delta9-tetrahydrocannabinol discrimination involves endogenous anandamide.
Journal: The Journal of pharmacology and experimental therapeutics 20070601
Title: Anandamide-mediated CB1/CB2 cannabinoid receptor--independent nitric oxide production in rabbit aortic endothelial cells.
Journal: The Journal of pharmacology and experimental therapeutics 20070601
Title: Persistent synaptic activity produces long-lasting enhancement of endocannabinoid modulation and alters long-term synaptic plasticity.
Journal: Journal of neurophysiology 20070601
Title: Genetic variations at the endocannabinoid type 1 receptor gene (CNR1) are associated with obesity phenotypes in men.
Journal: The Journal of clinical endocrinology and metabolism 20070601
Title: Cannabinoids as therapeutic agents in cardiovascular disease: a tale of passions and illusions.
Journal: British journal of pharmacology 20070601
Title: The endocannabinoid system and rimonabant: a new drug with a novel mechanism of action involving cannabinoid CB1 receptor antagonism--or inverse agonism--as potential obesity treatment and other therapeutic use.
Journal: Journal of clinical pharmacy and therapeutics 20070601
Title: Rimonabant as an adjunct therapy in overweight/obese patients with type 2 diabetes.
Journal: European heart journal 20070601
Title: Effects of combined oleoyl-estrone and rimonabant on overweight rats.
Journal: Journal of pharmacological sciences 20070601
Title: Less weight or more hype with rimonabant?
Journal: Drug and therapeutics bulletin 20070601
Title: Rimonabant, obesity and diabetes.
Journal: Prescrire international 20070601
Title: The endocannabinoid system: a new target for the regulation of energy balance and metabolism.
Journal: Critical pathways in cardiology 20070601
Title: Cardiovascular disease under the influence of excess visceral fat.
Journal: Critical pathways in cardiology 20070601
Title: Rimonabant for treating tobacco dependence.
Journal: Vascular health and risk management 20070601
Title: Endocannabinoid system--a novel target for cardiometabolic risk.
Journal: The Journal of the Association of Physicians of India 20070601
Title: [Three studies in type 2 diabetes: SERENADE the rimonabant (a blocker of the CB 1 receptors) in monotherapy in type 2 diabetes].
Journal: Annales d'endocrinologie 20070601
Title: Status epilepticus causes a long-lasting redistribution of hippocampal cannabinoid type 1 receptor expression and function in the rat pilocarpine model of acquired epilepsy.
Journal: Neuroscience 20070525
Title: Optimization of imidazole amide derivatives as cannabinoid-1 receptor antagonists for the treatment of obesity.
Journal: Bioorganic & medicinal chemistry letters 20070515
Title: Inhibition of fatty-acid amide hydrolase accelerates acquisition and extinction rates in a spatial memory task.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070501
Title: The link between abdominal obesity, metabolic syndrome and cardiovascular disease.
Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20070501
Title: Depolarization-induced rapid generation of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, in rat brain synaptosomes.
Journal: Journal of biochemistry 20070501
Title: Is rimonabant a safe and effective treatment for obesity?
Journal: Nature clinical practice. Endocrinology & metabolism 20070501
Title: Continuous infusion of the cannabinoid WIN 55,212-2 to the site of a peripheral nerve injury reduces mechanical and cold hypersensitivity.
Journal: British journal of pharmacology 20070501
Title: The role of endocannabinoid system blockade in the treatment of the metabolic syndrome.
Journal: Journal of clinical pharmacology 20070501
Title: Cannabinoid and vanilloid effects of R(+)-methanandamide in the hemisected meningeal preparation.
Journal: Cephalalgia : an international journal of headache 20070501
Title: Rimonabant as potential treatment for the neglected epidemic of diabetes in the Middle East and Arabian Peninsula. Implication for prevention.
Journal: Saudi medical journal 20070501
Title: Drug treatment of the overweight patient.
Journal: Gastroenterology 20070501
Title: Interactions between endocannabinoids and stress-induced decreased sensitivity to natural reward.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20070413
Title: [New therapeutic aspects for the control of risk factors in obesity].
Journal: Medicina clinica 20070407
Title: The endogenous cannabinoid anandamide produces delta-9-tetrahydrocannabinol-like discriminative and neurochemical effects that are enhanced by inhibition of fatty acid amide hydrolase but not by inhibition of anandamide transport.
Journal: The Journal of pharmacology and experimental therapeutics 20070401
Title: The disruptive effects of the CB1 receptor antagonist rimonabant on extinction learning in mice are task-specific.
Journal: Psychopharmacology 20070401
Title: Medial forebrain bundle stimulation evokes endocannabinoid-mediated modulation of ventral tegmental area dopamine neuron firing in vivo.
Journal: Psychopharmacology 20070401
Title: Effects of CB1 antagonist on the control of metabolic functions in obese type 2 diabetic patients.
Journal: Diabetes & metabolism 20070401
Title: Correlated species differences in the effects of cannabinoid ligands on anxiety and on GABAergic and glutamatergic synaptic transmission.
Journal: The European journal of neuroscience 20070401
Title: Effects of the cannabinoid antagonist SR141716 (rimonabant) and d-amphetamine on palatable food and food pellet intake in non-human primates.
Journal: Pharmacology, biochemistry, and behavior 20070401
Title: New oral agents for type 2 diabetes.
Journal: Clinical medicine (London, England) 20070401
Title: Potential role of the endocannabinoid receptor antagonist rimonabant in the management of cardiometabolic risk: a narrative review of available data.
Journal: Vascular health and risk management 20070401
Title: The endocannabinoid system as a novel approach for managing obesity.
Journal: The Journal of the American Osteopathic Association 20070401
Title: Modulation of morphine and alcohol motor stimulant effects by cannabinoid receptors ligands.
Journal: Behavioural brain research 20070328
Title: Delta9-tetrahydrocannabinol (Delta9-THC) prevents cerebral infarction via hypothalamic-independent hypothermia.
Journal: Life sciences 20070327
Title: Cannabinoid CB1 receptor antagonism markedly increases dopamine receptor-mediated stereotypies.
Journal: European journal of pharmacology 20070322
Title: 2-Arachidonylglyceryl ether and abnormal cannabidiol-induced vascular smooth muscle relaxation in rabbit pulmonary arteries via receptor-pertussis toxin sensitive G proteins-ERK1/2 signaling.
Journal: European journal of pharmacology 20070322
Title: [Internal medicine--update 2006].
Journal: Praxis 20070314
Title: Exercise reduces adipose tissue via cannabinoid receptor type 1 which is regulated by peroxisome proliferator-activated receptor-delta.
Journal: Biochemical and biophysical research communications 20070309
Title: Chronic use of marijuana decreases cannabinoid receptor binding and mRNA expression in the human brain.
Journal: Neuroscience 20070302
Title: Adolescent cannabis exposure alters opiate intake and opioid limbic neuronal populations in adult rats.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070301
Title: A novel role of cannabinoids: implication in the fever induced by bacterial lipopolysaccharide.
Journal: The Journal of pharmacology and experimental therapeutics 20070301
Title: Hallucinatory and rewarding effect of salvinorin A in zebrafish: kappa-opioid and CB1-cannabinoid receptor involvement.
Journal: Psychopharmacology 20070301
Title: Rimonabant: more than an anti-obesity drug?
Journal: British journal of pharmacology 20070301
Title: Effect of the cannabinoid CB1 receptor antagonist rimonabant on nociceptive responses and adjuvant-induced arthritis in obese and lean rats.
Journal: British journal of pharmacology 20070301
Title: Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro.
Journal: British journal of pharmacology 20070301
Title: Genetic and pharmacological approaches to evaluate the interaction between the cannabinoid and cholinergic systems in cognitive processes.
Journal: British journal of pharmacology 20070301
Title: Antagonism of type-1 cannabinoid receptors: good for obesity, but is it safe for fertility?
Journal: Clinical endocrinology 20070301
Title: Repeated treatment with cannabidiol but not Delta9-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance.
Journal: Neuropharmacology 20070301
Title: Role of the endocannabinoid system in regulating cardiovascular and metabolic risk factors.
Journal: The American journal of medicine 20070301
Title: Therapeutic options for modifying cardiometabolic risk factors.
Journal: The American journal of medicine 20070301
Title: Rimonabant: a novel selective cannabinoid-1 receptor antagonist for treatment of obesity.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070301
Title: [Cannabis and cannabinoids as drugs].
Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20070301
Title: [Endocannabinoids: therapeutic perspectives in chronic liver diseases].
Journal: Gastroenterologie clinique et biologique 20070301
Title: Chronic cocaine sensitizes striatal GABAergic synapses to the stimulation of cannabinoid CB1 receptors.
Journal: The European journal of neuroscience 20070301
Title: Weight management for type 2 diabetes mellitus: global cardiovascular risk reduction.
Journal: The American journal of cardiology 20070219
Title: Rimonabant in obese patients with type 2 diabetes.
Journal: Lancet (London, England) 20070217
Title: Rimonabant in obese patients with type 2 diabetes.
Journal: Lancet (London, England) 20070217
Title: Rimonabant in obese patients with type 2 diabetes.
Journal: Lancet (London, England) 20070217
Title: Rimonabant in obese patients with type 2 diabetes.
Journal: Lancet (London, England) 20070217
Title: The CB1 cannabinoid receptor antagonist rimonabant chronically prevents the nicotine-induced relapse to alcohol.
Journal: Neurobiology of disease 20070201
Title: Cannabimimetic properties of ajulemic acid.
Journal: The Journal of pharmacology and experimental therapeutics 20070201
Title: Constrained analogs of CB-1 antagonists: 1,5,6,7-Tetrahydro-4H-pyrrolo[3,2-c]pyridine-4-one derivatives.
Journal: Bioorganic & medicinal chemistry letters 20070201
Title: The effects of anorexic drugs on free-fed rats responding under a second-order FI15-min (FR10:S) schedule for high incentive foods.
Journal: Behavioural pharmacology 20070201
Title: Endocannabinoid antagonism: blocking the excess in the treatment of high-risk abdominal obesity.
Journal: Trends in cardiovascular medicine 20070201
Title: Endocannabinoid blockade for improving glycemic control and lipids in patients with type 2 diabetes mellitus.
Journal: The American journal of medicine 20070201
Title: CB2 cannabinoid receptors promote mouse neural stem cell proliferation.
Journal: The European journal of neuroscience 20070201
Title: [Cardiometabolic effects of rimonabant in obese/overweight subjects with dyslipidaemia or type 2 diabetes].
Journal: Revue medicale de Liege 20070201
Title: Phasic dopamine release evoked by abused substances requires cannabinoid receptor activation.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070124
Title: Antidepressant-induced undesirable weight gain: prevention with rimonabant without interference with behavioral effectiveness.
Journal: European journal of pharmacology 20070112
Title: Drug treatments for obesity: orlistat, sibutramine, and rimonabant.
Journal: Lancet (London, England) 20070106
Title: Cannabinoid CB1 receptor antagonists cause status epilepticus-like activity in the hippocampal neuronal culture model of acquired epilepsy.
Journal: Neuroscience letters 20070103
Title: WIN-55,212-2 and SR-141716A alter nicotine-induced changes in locomotor activity, but do not alter nicotine-evoked [3H]dopamine release.
Journal: Life sciences 20070102
Title: Genetic impairment of frontocortical endocannabinoid degradation and high alcohol preference.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070101
Title: An endocannabinoid mechanism in relapse to drug seeking: a review of animal studies and clinical perspectives.
Journal: Brain research reviews 20070101
Title: The obesity epidemic: current and future pharmacological treatments.
Journal: Annual review of pharmacology and toxicology 20070101
Title: Cannabinoid (CB1) receptor activation inhibits trigeminovascular neurons.
Journal: The Journal of pharmacology and experimental therapeutics 20070101
Title: Anandamide inhibits endothelin-1 production by human cultured endothelial cells: a new vascular action of this endocannabinoid.
Journal: Pharmacology 20070101
Title: Activation of peripheral cannabinoid CB1 and CB2 receptors suppresses the maintenance of inflammatory nociception: a comparative analysis.
Journal: British journal of pharmacology 20070101
Title: Non-nicotinic therapies for smoking cessation.
Journal: Annual review of pharmacology and toxicology 20070101
Title: [Rimonabant actions on cardiometabolic risk factors].
Journal: Medizinische Monatsschrift fur Pharmazeuten 20070101
Title: Cannabinoid receptor antagonists and the metabolic syndrome: Novel promising therapeutical approaches.
Journal: Mini reviews in medicinal chemistry 20070101
Title: High reinforcing efficacy of nicotine in non-human primates.
Journal: PloS one 20070101
Title: [The role of the endocannabinoid system in the regulation of endocrine function and in the control of energy balance in humans].
Journal: Postepy higieny i medycyny doswiadczalnej (Online) 20070101
Title: Smoking cessation pharmacotherapy--nicotine and non-nicotine preparations.
Journal: Preventive cardiology 20070101
Title: Oleamide: a fatty acid amide signaling molecule in the cardiovascular system?
Journal: Cardiovascular drug reviews 20070101
Title: Retrograde endocannabinoid inhibition of goldfish retinal cones is mediated by 2-arachidonoyl glycerol.
Journal: Visual neuroscience 20070101
Title: [What do we know about obesity?].
Journal: La Clinica terapeutica 20070101
Title: Special report on the Sanofi-Aventis cardiometabolic symposium.
Journal: Cardiovascular journal of Africa 20070101
Title: Endocannabinoid system and synaptic plasticity: implications for emotional responses.
Journal: Neural plasticity 20070101
Title: The Effect of PPARalpha, PPARdelta, PPARgamma, and PPARpan Agonists on Body Weight, Body Mass, and Serum Lipid Profiles in Diet-Induced Obese AKR/J Mice.
Journal: PPAR research 20070101
Title: [Recent advances in the management of obesity].
Journal: Revue medicale de Liege 20070101
Title: Evidence of accelerated ageing in clinical drug addiction from immune, hepatic and metabolic biomarkers.
Journal: Immunity & ageing : I & A 20070101
Title: Novel therapies for cardiometabolic risk reduction and implications for clinical practice.
Journal: Reviews in cardiovascular medicine 20070101
Title: Treatment of dyslipidemia to reduce cardiovascular risk in patients with multiple risk factors.
Journal: Clinical cornerstone 20070101
Title: High-density lipoprotein cholesterol and residual cardiometabolic risk in metabolic syndrome.
Journal: Clinical cornerstone 20070101
Title: Reducing cardiometabolic risk through selective antagonism of CB1 receptors.
Journal: Clinical cornerstone 20070101
Title: Effect of a weight loss intervention on anthropometric measures and metabolic risk factors in pre- versus postmenopausal women.
Journal: Nutrition journal 20070101
Title: Multiple impacts of rimonabant on cardiometabolic risk and safety addressed at ESC congress, Vienna.
Journal: Cardiovascular journal of Africa 20070101
Title: A possible role for the endocannabinoid system in the neurobiology of depression.
Journal: Clinical practice and epidemiology in mental health : CP & EMH 20070101
Title: Role of the endocannabinoid system in management of patients with type 2 diabetes mellitus and cardiovascular risk factors.
Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20070101
Title: [Pharmacology of cannabinoid receptors].
Journal: Bulletin de l'Academie nationale de medecine 20070101
Title: Altered gene expression and functional activity of opioid receptors in the cerebellum of CB1 cannabinoid receptor knockout mice after acute treatments with cannabinoids.
Journal: Acta biologica Hungarica 20070101
Title: Overweight and obesity: key components of cardiometabolic risk.
Journal: Clinical cornerstone 20070101
Title: Rimonabant: the evidence for its use in the treatment of obesity and the metabolic syndrome.
Journal: Core evidence 20070101
Title: Endocannabinoids and cardiovascular prevention: real progress?
Journal: Heart international 20070101
Title: Discovery of N-[(1S,2S)-3-(4-Chlorophenyl)-2- (3-cyanophenyl)-1-methylpropyl]-2-methyl-2- {[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide (MK-0364), a novel, acyclic cannabinoid-1 receptor inverse agonist for the treatment of obesity.
Journal: Journal of medicinal chemistry 20061228
Title: Evaluation of the role of the arachidonic acid cascade in anandamide's in vivo effects in mice.
Journal: Life sciences 20061203
Title: Cannabinoid CB1 receptor antagonism modulates plasma corticosterone in rodents.
Journal: European journal of pharmacology 20061203
Title: Anxiolytic-like properties of the anandamide transport inhibitor AM404.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20061201
Title: The agonists for nociceptors are ubiquitous, but the modulators are specific: P2X receptors in the sensory neurons are modulated by cannabinoids.
Journal: Pflugers Archiv : European journal of physiology 20061201
Title: Effects of a cannabinoid agonist on spinal nociceptive neurons in a rodent model of neuropathic pain.
Journal: Journal of neurophysiology 20061201
Title: In vivo modulation of LPS-induced alterations in brain and peripheral cytokines and HPA axis activity by cannabinoids.
Journal: Journal of neuroimmunology 20061201
Title: Rimonabant: endocannabinoid inhibition for the metabolic syndrome.
Journal: International journal of clinical practice 20061201
Title: Metabolic syndrome treatment strategies.
Journal: Pharmacotherapy 20061201
Title: Emerging strategies for increasing high-density lipoprotein.
Journal: The American journal of cardiology 20061201
Title: Effects of rimonabant (SR141716) on fasting-induced hypothalamic-pituitary-adrenal axis and neuronal activation in lean and obese Zucker rats.
Journal: Diabetes 20061201
Title: [Pharmacotherapy of obesity].
Journal: Medizinische Monatsschrift fur Pharmazeuten 20061201
Title: Conformational characteristics of the interaction of SR141716A with the CB1 cannabinoid receptor as determined through the use of conformationally constrained analogs.
Journal: The AAPS journal 20061201
Title: Cardiometabolic risk modification: current trends and emerging therapies.
Journal: JAAPA : official journal of the American Academy of Physician Assistants 20061201
Title: 6-(4-chlorophenyl)-3-substituted-thieno[3,2-d]pyrimidin-4(3H)-one-based melanin-concentrating hormone receptor 1 antagonist.
Journal: Journal of medicinal chemistry 20061130
Title: Involvement of 5-hydroxytryptamine1A receptors in Delta9-tetrahydrocannabinol-induced catalepsy-like immobilization in mice.
Journal: European journal of pharmacology 20061121
Title: The cannabinoid receptor agonist, WIN 55,212-2, inhibits cool-specific lamina I medullary dorsal horn neurons.
Journal: Neuroscience 20061117
Title: [A drug for therapy of obesity: really only life style? (interview by Dirk Einecke)].
Journal: MMW Fortschritte der Medizin 20061116
Title: Does rimonabant pull its weight for type 2 diabetes?
Journal: Lancet (London, England) 20061111
Title: Efficacy and tolerability of rimonabant in overweight or obese patients with type 2 diabetes: a randomised controlled study.
Journal: Lancet (London, England) 20061111
Title: Prenatal exposure to the cannabinoid receptor agonist WIN 55,212-2 and carbon monoxide reduces extracellular glutamate levels in primary rat cerebral cortex cell cultures.
Journal: Neurochemistry international 20061101
Title: Differential involvement of the endocannabinoid system in short- and long-term expression of incentive learning supported by nicotine in rats.
Journal: Psychopharmacology 20061101
Title: Rimonabant as a potential new treatment for an emerging epidemic of obesity-related glomerulopathy?
Journal: Expert opinion on emerging drugs 20061101
Title: [Acomplia, an essential medication or a 'comfort' product?].
Journal: Revue medicale suisse 20061101
Title: The endocannabinoid system as a target for the treatment of visceral obesity and metabolic syndrome.
Journal: Annals of the New York Academy of Sciences 20061101
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20061101
Title: Role of cannabinoid receptors in the regulation of cardiac contractility during ischemia/reperfusion.
Journal: Bulletin of experimental biology and medicine 20061101
Title: Rimonabant for overweight or obesity.
Journal: The Cochrane database of systematic reviews 20061018
Title: Cannabinoid receptor-mediated inhibition of calcium signaling in rat retinal ganglion cells.
Journal: Molecular vision 20061006
Title: Biarylpyrazole inverse agonists at the cannabinoid CB1 receptor: importance of the C-3 carboxamide oxygen/lysine3.28(192) interaction.
Journal: Journal of medicinal chemistry 20061005
Title: [Successful treatment of obesity].
Journal: MMW Fortschritte der Medizin 20061005
Title: Better strategies sought against obesity.
Journal: JAMA 20061004
Title: Protective activation of the endocannabinoid system during ischemia in dopamine neurons.
Journal: Neurobiology of disease 20061001
Title: The cannabinoid CB1 receptor antagonist rimonabant (SR141716) inhibits human breast cancer cell proliferation through a lipid raft-mediated mechanism.
Journal: Molecular pharmacology 20061001
Title: CB1 receptor antagonism increases hippocampal acetylcholine release: site and mechanism of action.
Journal: Molecular pharmacology 20061001
Title: Translation of nondopaminergic treatments for levodopa-induced dyskinesia from MPTP-lesioned nonhuman primates to phase IIa clinical studies: keys to success and roads to failure.
Journal: Movement disorders : official journal of the Movement Disorder Society 20061001
Title: Discriminative stimulus functions of AM-1346, a CB1R selective anandamide analog in rats trained with Delta9-THC or (R)-methanandamide (AM-356).
Journal: Psychopharmacology 20061001
Title: Effects of endocannabinoid neurotransmission modulators on brain stimulation reward.
Journal: Psychopharmacology 20061001
Title: Discriminative stimulus effects of the cannabinoid CB1 antagonist SR 141716A in rhesus monkeys pretreated with Delta9-tetrahydrocannabinol.
Journal: Psychopharmacology 20061001
Title: Involvement of cannabinoid receptors in inflammatory hypersensitivity to colonic distension in rats.
Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20061001
Title: Cannabinoid-serotonin interactions in alcohol-preferring vs. alcohol-avoiding mice.
Journal: Journal of neurochemistry 20061001
Title: 11C-JHU75528: a radiotracer for PET imaging of CB1 cannabinoid receptors.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20061001
Title: Obesity drug development - CBI's 2nd Annual Summit.
Journal: IDrugs : the investigational drugs journal 20061001
Title: Neuropathic pain and the endocannabinoid system in the dorsal raphe: pharmacological treatment and interactions with the serotonergic system.
Journal: The European journal of neuroscience 20061001
Title: Pharmacotherapy of obesity.
Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20061001
Title: Non-cannabinoid CB1, non-cannabinoid CB2 antinociceptive effects of several novel compounds in the PPQ stretch test in mice.
Journal: European journal of pharmacology 20060928
Title: Analysis of the effects of cannabinoids on identified synaptic connections in the caudate-putamen by paired recordings in transgenic mice.
Journal: The Journal of physiology 20060915
Title: A cannabinoid receptor 1 mutation proximal to the DRY motif results in constitutive activity and reveals intramolecular interactions involved in receptor activation.
Journal: Brain research 20060907
Title: Effects of the cannabinoid CB1 receptor agonist CP55,940 and antagonist SR141716A on d-amphetamine-induced behaviours in Cebus monkeys.
Journal: Journal of psychopharmacology (Oxford, England) 20060901
Title: Antinociceptive activity of chemical congeners of improgan: optimization of side chain length leads to the discovery of a new, potent, non-opioid analgesic.
Journal: Neuropharmacology 20060901
Title: Interactions between CB1 cannabinoid and mu opioid receptors mediating inhibition of neurotransmitter release in rat nucleus accumbens core.
Journal: Neuropharmacology 20060901
Title: Neuroprotective cannabinoid receptor antagonist SR141716A prevents downregulation of excitotoxic NMDA receptors in the ischemic penumbra.
Journal: Acta neuropathologica 20060901
Title: SR 141716 (Rimonabant) precipitates withdrawal in marijuana-dependent mice.
Journal: Pharmacology, biochemistry, and behavior 20060901
Title: Effects of the CB1R agonist WIN-55,212-2 and the CB1R antagonists SR-141716 and AM-1387: open-field examination in rats.
Journal: Pharmacology, biochemistry, and behavior 20060901
Title: Critical appraisal of C-reactive protein throughout the spectrum of cardiovascular disease.
Journal: Vascular health and risk management 20060901
Title: Metabolic syndrome: the danger signal in atherosclerosis.
Journal: Vascular health and risk management 20060901
Title: [Cardiac metabolic risk factors. CB1-blocker corrects three with one stroke].
Journal: MMW Fortschritte der Medizin 20060831
Title: Cannabinoid-1 receptor antagonist, rimonabant, for management of obesity and related risks.
Journal: Circulation 20060829
Title: Endogenous cannabinoid signaling through the CB1 receptor is essential for cerebellum-dependent discrete motor learning.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060823
Title: [Rimonabant improves cardiometabolic risk profile in obese or overweight subjects: overview of RIO studies].
Journal: Revue medicale suisse 20060823
Title: Morphine reduces penile erection induced by the cannabinoid receptor antagonist SR 141617A in male rats: role of paraventricular glutamic acid and nitric oxide.
Journal: Neuroscience letters 20060814
Title: Effect of rimonabant on weight and cardiometabolic risk factors.
Journal: JAMA 20060809
Title: Early tolerance to the hypophagic effect of the cannabinoid receptor antagonist SR141716 does not impede blockade of an orexigenic stimulus.
Journal: European journal of pharmacology 20060807
Title: Evaluation of the in vivo receptor occupancy for the behavioral effects of cannabinoids using a radiolabeled cannabinoid receptor agonist, R-[125/131I]AM2233.
Journal: Synapse (New York, N.Y.) 20060801
Title: Antiobesity effects of the novel in vivo neutral cannabinoid receptor antagonist 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-hexyl-1H-1,2,4-triazole--LH 21.
Journal: Neuropharmacology 20060801
Title: Tolerance to cannabinoid response on the myenteric plexus of guinea-pig ileum and human small intestinal strips.
Journal: British journal of pharmacology 20060801
Title: Investigation on the relationship between cannabinoid CB1 and opioid receptors in gastrointestinal motility in mice.
Journal: British journal of pharmacology 20060801
Title: Characterization of the neuroprotective effect of the cannabinoid agonist WIN-55212 in an in vitro model of hypoxic-ischemic brain damage in newborn rats.
Journal: Pediatric research 20060801
Title: Fatty acid amide hydrolase deficiency limits early pregnancy events.
Journal: The Journal of clinical investigation 20060801
Title: Coming soon: the lose-weight-stop-smoking pill that's good for your heart.
Journal: Health news (Waltham, Mass.) 20060801
Title: Pharmacologic treatment for obesity. Options for today...and tomorrow.
Journal: Advance for nurse practitioners 20060801
Title: Rimonabant: new drug. Obesity: loss of a few kilos, many questions.
Journal: Prescrire international 20060801
Title: [Rimonabant--a panacea for patients with metabolic syndrome?].
Journal: Polskie Archiwum Medycyny Wewnetrznej 20060801
Title: [Blockage of the CB1 cannabinoid receptor for the prevention of liver cirrhosis ].
Journal: Revue medicale suisse 20060712
Title: Neural contractions in colonic strips from patients with diverticular disease: role of endocannabinoids and substance P.
Journal: Gut 20060701
Title: Synthesis and preliminary biological evaluation of [123I]Me2Pyr, a new potential ligand for imaging of central cannabinoid CB1 receptors.
Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20060701
Title: Pharmacological evaluation of cannabinoid receptor ligands in a mouse model of anxiety: further evidence for an anxiolytic role for endogenous cannabinoid signaling.
Journal: The Journal of pharmacology and experimental therapeutics 20060701
Title: Sphingosine and its analog, the immunosuppressant 2-amino-2-(2-[4-octylphenyl]ethyl)-1,3-propanediol, interact with the CB1 cannabinoid receptor.
Journal: Molecular pharmacology 20060701
Title: Evaluation of the role of nicotinic acetylcholine receptor subtypes and cannabinoid system in the discriminative stimulus effects of nicotine in rats.
Journal: European journal of pharmacology 20060701
Title: The obesity epidemic and its cardiovascular consequences.
Journal: Current opinion in cardiology 20060701
Title: Amygdala BDNF signaling is required for consolidation but not encoding of extinction.
Journal: Nature neuroscience 20060701
Title: Anandamide administration alone and after inhibition of fatty acid amide hydrolase (FAAH) increases dopamine levels in the nucleus accumbens shell in rats.
Journal: Journal of neurochemistry 20060701
Title: Is rimonabant a safe and effective therapy for sustained weight loss and improved cardiometabolic risk factors?
Journal: Nature clinical practice. Cardiovascular medicine 20060701
Title: SR147778, a CB1 cannabinoid receptor antagonist, suppresses ethanol preference in chronically alcoholized Wistar rats.
Journal: Alcohol (Fayetteville, N.Y.) 20060701
Title: [Smoking cessation intervention: 2006 update].
Journal: Revue medicale suisse 20060628
Title: CB1 knockout mice display significant changes in striatal opioid peptide and D4 dopamine receptor gene expression.
Journal: Brain research 20060606
Title: Influence of the anabolic-androgenic steroid nandrolone on cannabinoid dependence.
Journal: Neuropharmacology 20060601
Title: Synthesis and structure-activity relationships (SARs) of 1,5-diarylpyrazole cannabinoid type-1 (CB(1)) receptor ligands for potential use in molecular imaging.
Journal: Bioorganic & medicinal chemistry 20060601
Title: Modulation of neuropathic and inflammatory pain by the endocannabinoid transport inhibitor AM404 [N-(4-hydroxyphenyl)-eicosa-5,8,11,14-tetraenamide].
Journal: The Journal of pharmacology and experimental therapeutics 20060601
Title: CB1 cannabinoid receptor antagonism: a new strategy for the treatment of liver fibrosis.
Journal: Nature medicine 20060601
Title: G protein-coupled receptors in regulation of body weight.
Journal: CNS & neurological disorders drug targets 20060601
Title: The cannabinoid CB1 receptor inverse agonist, rimonabant, modifies body weight and adiponectin function in diet-induced obese rats as a consequence of reduced food intake.
Journal: Pharmacology, biochemistry, and behavior 20060601
Title: Antipsychotics improve Delta9-tetrahydrocannabinol-induced impairment of the prepulse inhibition of the startle reflex in mice.
Journal: Pharmacology, biochemistry, and behavior 20060601
Title: [Impact of endocannabinoid system in modulation of cardiometabolic risk factors].
Journal: Vnitrni lekarstvi 20060601
Title: Potential role of new therapies in modifying cardiovascular risk in overweight patients with metabolic risk factors.
Journal: Obesity (Silver Spring, Md.) 20060601
Title: Rimonabant: a cannabinoid receptor type 1 blocker for management of multiple cardiometabolic risk factors.
Journal: Journal of the American College of Cardiology 20060516
Title: The cannabinoid CB1 receptor antagonist SR 141716A induces penile erection by increasing extra-cellular glutamic acid in the paraventricular nucleus of male rats.
Journal: Behavioural brain research 20060515
Title: Treatments for metabolic syndrome may expand.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20060515
Title: Mutations of CB1 T210 produce active and inactive receptor forms: correlations with ligand affinity, receptor stability, and cellular localization.
Journal: Biochemistry 20060502
Title: Cannabinoid effects on behaviors maintained by ethanol or food: a within-subjects comparison.
Journal: Behavioural pharmacology 20060501
Title: Cannabinoid agonist WIN55,212-2 induces apoptosis in cerebellar granule cells via activation of the CB1 receptor and downregulation of bcl-xL gene expression.
Journal: Journal of neuroscience research 20060501
Title: Update on rimonabant--a selective cannabinoid CB1 antagonist.
Journal: The Annals of pharmacotherapy 20060501
Title: Noladin ether acts on trabecular meshwork cannabinoid (CB1) receptors to enhance aqueous humor outflow facility.
Journal: Investigative ophthalmology & visual science 20060501
Title: Cannabinoid modulation of electrically evoked pH and oxygen transients in the nucleus accumbens of awake rats.
Journal: Journal of neurochemistry 20060501
Title: Analysis of recent papers in hypertension: differences in central aortic blood pressure explain outcome differences in ASCOT: the CAFE substudy; and rimonabant improves multiple cardiometabolic parameters in overweight and obese individuals.
Journal: Journal of clinical hypertension (Greenwich, Conn.) 20060501
Title: Cannabinoids modulate spontaneous neuronal activity and evoked inhibition of locus coeruleus noradrenergic neurons.
Journal: The European journal of neuroscience 20060501
Title: 2-Arachidonylglycerol acting on CB1 cannabinoid receptors mediates delayed cardioprotection induced by nitric oxide in rat isolated hearts.
Journal: Journal of cardiovascular pharmacology 20060501
Title: Role of the basolateral nucleus of the amygdala in endocannabinoid-mediated stress-induced analgesia.
Journal: Neuroscience letters 20060424
Title: Cannabinoid modulation of opiate reinforcement through the ventral striatopallidal pathway.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060401
Title: Involvement of the endocannabinoid system in drug addiction.
Journal: Trends in neurosciences 20060401
Title: Lack of tolerance to the suppressing effect of rimonabant on chocolate intake in rats.
Journal: Psychopharmacology 20060401
Title: Diabetes: assessing the pipeline.
Journal: Atherosclerosis. Supplements 20060401
Title: Optimal treatments for the metabolic syndrome.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20060401
Title: The unfolding cannabinoid story on energy homeostasis: central or peripheral site of action?
Journal: International journal of obesity (2005) 20060401
Title: How many sites of action for endocannabinoids to control energy metabolism?
Journal: International journal of obesity (2005) 20060401
Title: Contribution of CB1 blockade to the management of high-risk abdominal obesity.
Journal: International journal of obesity (2005) 20060401
Title: Obesity drugs in clinical development.
Journal: Current opinion in investigational drugs (London, England : 2000) 20060401
Title: Role of TRPV1 and cannabinoid CB1 receptors in AM 404-evoked hypothermia in rats.
Journal: Pharmacology, biochemistry, and behavior 20060401
Title: Pharmacological treatment of obesity.
Journal: Arquivos brasileiros de endocrinologia e metabologia 20060401
Title: [The endocannabinoid system: a new paradigm in the metabolic syndrome treatment].
Journal: Arquivos brasileiros de endocrinologia e metabologia 20060401
Title: The new cancer fighter (and other hot drugs on the way).
Journal: Time 20060320
Title: Systemic effect of cannabinoids on the spontaneous firing rate of locus coeruleus neurons in rats.
Journal: European journal of pharmacology 20060318
Title: The CB1 cannabinoid receptor is the major cannabinoid receptor at excitatory presynaptic sites in the hippocampus and cerebellum.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060315
Title: Metabolic risk factors, drugs, and obesity.
Journal: The New England journal of medicine 20060302
Title: [Pharmacotherapy in the treatment of obesity].
Journal: MMW Fortschritte der Medizin 20060302
Title: Molecular mechanisms of cannabinoid protection from neuronal excitotoxicity.
Journal: Molecular pharmacology 20060301
Title: Endocannabinoids at the spinal level regulate, but do not mediate, nonopioid stress-induced analgesia.
Journal: Neuropharmacology 20060301
Title: Vasorelaxant effects of oleamide in rat small mesenteric artery indicate action at a novel cannabinoid receptor.
Journal: British journal of pharmacology 20060301
Title: Role of the cannabinoid system in the effects induced by nicotine on anxiety-like behaviour in mice.
Journal: Psychopharmacology 20060301
Title: Vanilloid VR1 receptor is involved in rimonabant-induced neuroprotection.
Journal: British journal of pharmacology 20060301
Title: Effects of castration on cannabinoid cb receptor expression and on the biological actions of cannabinoid in the parotid gland.
Journal: Clinical and experimental pharmacology & physiology 20060301
Title: Rimonabant: a cannabinoid receptor blocker for the treatment of metabolic and cardiovascular risk factors.
Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20060301
Title: Rimonabant: a selective blocker of the cannabinoid CB1 receptors for the management of obesity, smoking cessation and cardiometabolic risk factors.
Journal: Expert opinion on investigational drugs 20060301
Title: The cannabinoid CB1 receptor antagonist rimonabant attenuates the hypotensive effect of smoked marijuana in male smokers.
Journal: American heart journal 20060301
Title: Pharmacologic interventions for smoking cessation.
Journal: Critical care nursing clinics of North America 20060301
Title: Effects of rimonabant, a selective cannabinoid CB1 receptor antagonist, in a rat model of Parkinson's disease.
Journal: Brain research 20060216
Title: Anandamide inhibits adhesion and migration of breast cancer cells.
Journal: Experimental cell research 20060215
Title: The analgesic activity of paracetamol is prevented by the blockade of cannabinoid CB1 receptors.
Journal: European journal of pharmacology 20060215
Title: Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: a randomized controlled trial.
Journal: JAMA 20060215
Title: Effects of exogenous and endogenous cannabinoids on GABAergic neurotransmission between the caudate-putamen and the globus pallidus in the mouse.
Journal: The Journal of pharmacology and experimental therapeutics 20060201
Title: New bicyclic cannabinoid receptor-1 (CB1-R) antagonists.
Journal: Bioorganic & medicinal chemistry letters 20060201
Title: The cannabinoid CB1 receptor antagonist rimonabant (SR141716) inhibits cell proliferation and increases markers of adipocyte maturation in cultured mouse 3T3 F442A preadipocytes.
Journal: Molecular pharmacology 20060201
Title: The cannabinoid receptor antagonist SR-141716A induces penile erection in male rats: involvement of paraventricular glutamic acid and nitric oxide.
Journal: Neuropharmacology 20060201
Title: Neuropharmacology and potential efficacy of new treatments for tobacco dependence.
Journal: Expert opinion on investigational drugs 20060201
Title: The endocannabinoid system: current pharmacological research and therapeutic possibilities.
Journal: Basic & clinical pharmacology & toxicology 20060201
Title: Cannabidiol is an allosteric modulator at mu- and delta-opioid receptors.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20060201
Title: Effects of cannabinoid receptor agonists on rat gastric acid secretion: discrepancy between in vitro and in vivo data.
Journal: Digestive diseases and sciences 20060201
Title: Cardiovascular risk management by blocking the endocannabinoid system.
Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20060201
Title: Drug development. Drugs inspired by a drug.
Journal: Science (New York, N.Y.) 20060120
Title: Suppression of feeding, drinking, and locomotion by a putative cannabinoid receptor 'silent antagonist'.
Journal: European journal of pharmacology 20060113
Title: Novel 4-oxo-1,4-dihydroquinoline-3-carboxamide derivatives as new CB2 cannabinoid receptors agonists: synthesis, pharmacological properties and molecular modeling.
Journal: Journal of medicinal chemistry 20060112
Title: [Drug treatment of obesity].
Journal: Ugeskrift for laeger 20060109
Title: The effect of Delta9-tetrahydrocannabinol on sensorimotor gating in socially isolated rats.
Journal: Behavioural brain research 20060106
Title: [New obesity and metabolic syndrome treatment: rimonabant].
Journal: Revue medicale suisse 20060104
Title: Endocannabinoids affect neurological and cognitive function in thioacetamide-induced hepatic encephalopathy in mice.
Journal: Neurobiology of disease 20060101
Title: Antinociceptive effect of spinally administered cannabinergic and 2-adrenoceptor drugs on the formalin test in rat: possible interactions.
Journal: Journal of psychopharmacology (Oxford, England) 20060101
Title: Pharmacological manipulation of CB1 receptor function alters development of tolerance to alcohol.
Journal: Alcohol and alcoholism (Oxford, Oxfordshire) 20060101
Title: Pharmacotherapy for obesity.
Journal: Appetite 20060101
Title: Effect of the cannabinoid CB1 receptor antagonist SR-141716A on ethanol self-administration and ethanol-seeking behaviour in rats.
Journal: Psychopharmacology 20060101
Title: Structural-activity relationship study on C-4 carbon atom of the CB1 antagonist SR141716: synthesis and pharmacological evaluation of 1,2,4-triazole-3-carboxamides.
Journal: European journal of medicinal chemistry 20060101
Title: Antagonism of discriminative stimulus effects of delta(9)-THC and (R)-methanandamide in rats.
Journal: Psychopharmacology 20060101
Title: The relationship of in vivo central CB1 receptor occupancy to changes in cortical monoamine release and feeding elicited by CB1 receptor antagonists in rats.
Journal: Psychopharmacology 20060101
Title: American Heart Association--scientific sessions 2005. Potential new drugs for various indications. 13-16 November 2005, Dallas, TX, USA.
Journal: IDrugs : the investigational drugs journal 20060101
Title: Rimonabant adds appetizing choice to slim obesity market.
Journal: Nature medicine 20060101
Title: Pharmacologic treatment of obesity.
Journal: Advances in psychosomatic medicine 20060101
Title: Cannabinoid receptor agonists inhibit Ca(2+) influx to synaptosomes from rat brain.
Journal: Pharmacology 20060101
Title: [Reducing obesity].
Journal: Presse medicale (Paris, France : 1983) 20060101
Title: Developments in pharmacotherapy for tobacco dependence: past, present and future.
Journal: Drug and alcohol review 20060101
Title: Nicotine and non-nicotine smoking cessation pharmacotherapies.
Journal: Cardiology in review 20060101
Title: Methods evaluating cannabinoid and endocannabinoid effects on gastrointestinal functions.
Journal: Methods in molecular medicine 20060101
Title: Effect of N-arachidonoyl-(2-methyl-4-hydroxyphenyl) amine (VDM11), an anandamide transporter inhibitor, on capsaicin-induced cough in mice.
Journal: Cough (London, England) 20060101
Title: Therapeutic options in development for management of diabetes: pharmacologic agents and new technologies.
Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20060101
Title: Contemporary strategies for managing cardiometabolic risk factors.
Journal: Journal of managed care pharmacy : JMCP 20060101
Title: Intra-abdominal obesity: an untreated risk factor for Type 2 diabetes and cardiovascular disease.
Journal: Journal of endocrinological investigation 20060101
Title: New approaches for the management of patients with multiple cardiometabolic risk factors.
Journal: Journal of endocrinological investigation 20060101
Title: Clinical outcomes in metabolic syndrome.
Journal: The Journal of cardiovascular nursing 20060101
Title: The endocannabinoid system and cardiovascular risk: pathophysiologic role and developing therapeutic interventions.
Journal: The American journal of geriatric cardiology 20060101
Title: Obesity. Rimonabant trials confirm benefit.
Journal: Reviews in cardiovascular medicine 20060101
Title: Obesity: new perspectives and pharmacotherapies.
Journal: Cardiology in review 20060101
Title: Emerging pharmacotherapy for treating obesity and associated cardiometabolic risk.
Journal: Asia Pacific journal of clinical nutrition 20060101
Title: Efficacy of rimonabant and other cannabinoid CB1 receptor antagonists in reducing food intake and body weight: preclinical and clinical data.
Journal: CNS drug reviews 20060101
Title: Therapeutic potential of targeting the endocannabinoids: implications for the treatment of obesity, metabolic syndrome, drug abuse and smoking cessation.
Journal: Current medicinal chemistry 20060101
Title: Rimonabant.
Journal: Drugs 20060101
Title: [Selective cannabinoid receptor antagonists].
Journal: Pharmazie in unserer Zeit 20060101
Title: The relation of adipose tissue to cardiometabolic risk.
Journal: Clinical cornerstone 20060101
Title: The endocannabinoid system: body weight and metabolic regulation.
Journal: Clinical cornerstone 20060101
Title: Involvement of cannabinoid CB1 receptors in drug addiction: effects of rimonabant on behavioral responses induced by cocaine.
Journal: Pharmacological reports : PR 20060101
Title: In vitro effects of CB1 receptor ligands on lipid peroxidation and antioxidant defense systems in the rat brain.
Journal: Pharmacological reports : PR 20060101
Title: In vivo effects of CB1 receptor ligands on lipid peroxidation and antioxidant defense systems in the rat brain of healthy and ethanol-treated rats.
Journal: Pharmacological reports : PR 20060101
Title: Endocannabinoids--the brain's own marijuana--may be linked to the metabolic syndrome.
Journal: MedGenMed : Medscape general medicine 20060101
Title: Endocannabinoids and non-alcoholic steatohepatitis.
Journal: Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20060101
Title: The cannabinoid agonist WIN55,212-2 increases intracellular calcium via CB1 receptor coupling to Gq/11 G proteins.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20051227
Title: Decrease in prostaglandin level is a prerequisite for the expression of cannabinoid withdrawal: a quasi abstinence approach.
Journal: Brain research 20051220
Title: Cannabinoid receptor ligands mediate growth inhibition and cell death in mantle cell lymphoma.
Journal: FEBS letters 20051219
Title: Dual Ca2+ modulation of glycinergic synaptic currents in rodent hypoglossal motoneurones.
Journal: The Journal of physiology 20051215
Title: Capsaicin evokes hypothermia independent of cannabinoid CB1 and CB2 receptors.
Journal: Brain research 20051214
Title: Paraventricular hypothalamic CB(1) cannabinoid receptors are involved in the feeding stimulatory effects of Delta(9)-tetrahydrocannabinol.
Journal: Neuropharmacology 20051201
Title: Inhibition of fatty-acid amide hydrolase enhances cannabinoid stress-induced analgesia: sites of action in the dorsolateral periaqueductal gray and rostral ventromedial medulla.
Journal: Neuropharmacology 20051201
Title: Involvement of the endogenous cannabinoid system in the effects of alcohol in the mesolimbic reward circuit: electrophysiological evidence in vivo.
Journal: Psychopharmacology 20051201
Title: Tackling obesity and nicotine dependence.
Journal: IDrugs : the investigational drugs journal 20051201
Title: Pharmacological properties and therapeutic possibilities for drugs acting upon endocannabinoid receptors.
Journal: Current drug targets. CNS and neurological disorders 20051201
Title: Endocannabinoid receptor antagonists and other emerging pharma-cological strategies for weight reduction.
Journal: Current drug targets. Cardiovascular & haematological disorders 20051201
Title: [The formidable virtue announced for rimonabant, alias Acomplia].
Journal: Revue medicale suisse 20051130
Title: Tricyclic pyrazoles. 3. Synthesis, biological evaluation, and molecular modeling of analogues of the cannabinoid antagonist 8-chloro-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide.
Journal: Journal of medicinal chemistry 20051117
Title: 1-Benzhydryl-3-phenylurea and 1-benzhydryl-3-phenylthiourea derivatives: new templates among the CB1 cannabinoid receptor inverse agonists.
Journal: Journal of medicinal chemistry 20051117
Title: Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia.
Journal: The New England journal of medicine 20051117
Title: Pharmacotherapy for obesity--promise and uncertainty.
Journal: The New England journal of medicine 20051117
Title: Motivational effects of cannabinoids and opioids on food reinforcement depend on simultaneous activation of cannabinoid and opioid systems.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20051101
Title: Increasing treatment options for cannabis dependence: a review of potential pharmacotherapies.
Journal: Drug and alcohol dependence 20051101
Title: Effect of anandamide uptake inhibition in the production of nitric oxide and in the release of cytokines in astrocyte cultures.
Journal: Glia 20051101
Title: Allosteric modulation of the cannabinoid CB1 receptor.
Journal: Molecular pharmacology 20051101
Title: Novel 3,4-diarylpyrazolines as potent cannabinoid CB1 receptor antagonists with lower lipophilicity.
Journal: Bioorganic & medicinal chemistry letters 20051101
Title: Anandamide reduces infarct size in rat isolated hearts subjected to ischaemia-reperfusion by a novel cannabinoid mechanism.
Journal: British journal of pharmacology 20051101
Title: Safety of obesity drugs.
Journal: Expert opinion on drug safety 20051101
Title: Species and strain differences in the expression of a novel glutamate-modulating cannabinoid receptor in the rodent hippocampus.
Journal: The European journal of neuroscience 20051101
Title: [Medications in smoking cessation].
Journal: Presse medicale (Paris, France : 1983) 20051022
Title: Anandamide elicits an acute release of nitric oxide through endothelial TRPV1 receptor activation in the rat arterial mesenteric bed.
Journal: The Journal of physiology 20051015
Title: Weeding out new drugs.
Journal: Drug discovery today 20051015
Title: Involvement of the cannabinoid CB1 receptor in the opioid inhibition of the response to cholecystokinin and acute withdrawal response.
Journal: Neurotoxicology 20051001
Title: Inhibition of cyclooxygenase-2 elicits a CB1-mediated decrease of excitatory transmission in rat CA1 hippocampus.
Journal: Neuropharmacology 20051001
Title: Cannabinoid CB1 receptors are involved in motivational effects of nicotine in rats.
Journal: Psychopharmacology 20051001
Title: Inhibitors of fatty acid amide hydrolase reduce carrageenan-induced hind paw inflammation in pentobarbital-treated mice: comparison with indomethacin and possible involvement of cannabinoid receptors.
Journal: British journal of pharmacology 20051001
Title: VR1-mediated depressor effects during high-salt intake: role of anandamide.
Journal: Hypertension (Dallas, Tex. : 1979) 20051001
Title: Endocannabinoids and liver disease--review.
Journal: Liver international : official journal of the International Association for the Study of the Liver 20051001
Title: Drugs on the horizon for diabesity.
Journal: Current diabetes reports 20051001
Title: Is the cannabinoid CB1 receptor antagonist rimonabant advancing the treatment of obesity?
Journal: Expert opinion on pharmacotherapy 20051001
Title: New drugs for prevention, relief. How you might benefit if 3 medications win FDA approval.
Journal: Heart advisor 20051001
Title: A new 'wonder drug'?
Journal: Diabetes forecast 20051001
Title: The G alpha(o/i)-coupled cannabinoid receptor-mediated neurite outgrowth involves Rap regulation of Src and Stat3.
Journal: The Journal of biological chemistry 20050930
Title: Appetite downer awaits approval.
Journal: Nature 20050929
Title: Rimonabant: the first therapeutically relevant cannabinoid antagonist.
Journal: Life sciences 20050923
Title: Synthesis of long-chain amide analogs of the cannabinoid CB1 receptor antagonist N-(piperidinyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716) with unique binding selectivities and pharmacological activities.
Journal: Bioorganic & medicinal chemistry 20050915
Title: Retrograde endocannabinoid regulation of GABAergic inhibition in the rat dentate gyrus granule cell.
Journal: The Journal of physiology 20050915
Title: Mechanisms of HIV-1 inhibition by the lipid mediator N-arachidonoyldopamine.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20050915
Title: Synthesis and structure-activity relationship of a novel series of aminoalkylindoles with potential for imaging the neuronal cannabinoid receptor by positron emission tomography.
Journal: Journal of medicinal chemistry 20050908
Title: FDA standards--good enough for government work?
Journal: The New England journal of medicine 20050908
Title: Lack of CB1 cannabinoid receptor impairs cocaine self-administration.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050901
Title: The CB1 receptor antagonist rimonabant reverses the diet-induced obesity phenotype through the regulation of lipolysis and energy balance.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050901
Title: Endogenous cannabinoid receptor agonists inhibit neurogenic inflammations in guinea pig airways.
Journal: International archives of allergy and immunology 20050901
Title: New options for drug treatment of obesity in patients with Type 2 diabetes.
Journal: Diabetic medicine : a journal of the British Diabetic Association 20050901
Title: Obesity Drug Development Summit. 21-22 July, 2005, Arlington, VA, USA.
Journal: IDrugs : the investigational drugs journal 20050901
Title: Fatty acid amide hydrolase controls mouse intestinal motility in vivo.
Journal: Gastroenterology 20050901
Title: Current evidence supporting a role of cannabinoid CB1 receptor (CB1R) antagonists as potential pharmacotherapies for drug abuse disorders.
Journal: Behavioural pharmacology 20050901
Title: SR 141716A differentially attenuates the behavioral effects of delta9-THC in rhesus monkeys.
Journal: Behavioural pharmacology 20050901
Title: Delta9-THC induced hyperphagia and tolerance assessment: interactions between the CB1 receptor agonist delta9-THC and the CB1 receptor antagonist SR-141716 (rimonabant) in rats.
Journal: Behavioural pharmacology 20050901
Title: The role of CB1 receptors in sweet versus fat reinforcement: effect of CB1 receptor deletion, CB1 receptor antagonism (SR141716A) and CB1 receptor agonism (CP-55940).
Journal: Behavioural pharmacology 20050901
Title: Anxiogenic profile of AM-251, a selective cannabinoid CB1 receptor antagonist, in plus-maze-naïve and plus-maze-experienced mice.
Journal: Behavioural pharmacology 20050901
Title: Long-term behavioural and neuroendocrine effects of perinatal activation or blockade of CB1 cannabinoid receptors.
Journal: Behavioural pharmacology 20050901
Title: Behaviorally relevant endocannabinoid action in hippocampus: dependence on temporal summation of multiple inputs.
Journal: Behavioural pharmacology 20050901
Title: [In diabetes cannabinoid antagonist kills two birds with one stone].
Journal: MMW Fortschritte der Medizin 20050901
Title: [Innovative therapies in metabolic diseases: ezetimibe (Ezétrol), nicotinic acid (Niaspan), acids omega-3 (Omacor), rimonabant (Acomplia)].
Journal: Revue medicale de Bruxelles 20050901
Title: New drug policy in childhood obesity.
Journal: International journal of obesity (2005) 20050901
Title: Cannabinoid CB1 receptors control conditioned drug seeking.
Journal: Trends in pharmacological sciences 20050801
Title: A role for endocannabinoids in viral-induced dyskinetic and convulsive phenomena.
Journal: Experimental neurology 20050801
Title: [Rimonabant reduced body weight and blood sugar].
Journal: Medizinische Monatsschrift fur Pharmazeuten 20050801
Title: Cannabinoid CB1 receptor-mediated inhibition of noradrenaline release in guinea-pig vessels, but not in rat and mouse aorta.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20050801
Title: Rimonabant hydrochloride: an investigational agent for the management of cardiovascular risk factors.
Journal: Drugs of today (Barcelona, Spain : 1998) 20050801
Title: WIN 55,212-2-induced reduction of cocaine hyperlocomotion: possible inhibition of 5-HT(3) receptor function.
Journal: European journal of pharmacology 20050704
Title: Delta9-tetrahydrocannbinol accounts for the antinociceptive, hypothermic, and cataleptic effects of marijuana in mice.
Journal: The Journal of pharmacology and experimental therapeutics 20050701
Title: A role for endocannabinoids in the generation of parkinsonism and levodopa-induced dyskinesia in MPTP-lesioned non-human primate models of Parkinson's disease.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050701
Title: Effect of the cannabinoid CB1 receptor antagonist, SR141716, on nociceptive response and nerve demyelination in rodents with chronic constriction injury of the sciatic nerve.
Journal: Pain 20050701
Title: Inhibitory effects of CB1 and CB2 receptor agonists on responses of DRG neurons and dorsal horn neurons in neuropathic rats.
Journal: The European journal of neuroscience 20050701
Title: Effect of rimonabant on weight reduction and cardiovascular risk.
Journal: Lancet (London, England) 20050701
Title: Effect of rimonabant on weight reduction and cardiovascular risk.
Journal: Lancet (London, England) 20050701
Title: Effect of rimonabant on weight reduction and cardiovascular risk.
Journal: Lancet (London, England) 20050701
Title: Effect of rimonabant on weight reduction and cardiovascular risk.
Journal: Lancet (London, England) 20050701
Title: [Medication for ending tobacco dependency. Current state].
Journal: Atencion primaria 20050630
Title: Effect of delta9-tetrahydrocannabinol on phosphorylated CREB in rat cerebellum: an immunohistochemical study.
Journal: Brain research 20050628
Title: Cysteine residues in the human cannabinoid receptor: only C257 and C264 are required for a functional receptor, and steric bulk at C386 impairs antagonist SR141716A binding.
Journal: Biochemistry 20050621
Title: Abnormal sensitivity to cannabinoid receptor stimulation might contribute to altered gamma-aminobutyric acid transmission in the striatum of R6/2 Huntington's disease mice.
Journal: Biological psychiatry 20050615
Title: The endogenous cannabinoid anandamide and its synthetic analog R(+)-methanandamide are intravenously self-administered by squirrel monkeys.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050608
Title: Cannabinoid CB(1) receptors in the basal ganglia and motor response to activation or blockade of these receptors in parkin-null mice.
Journal: Brain research 20050607
Title: The cannabinoid antagonist SR141716A facilitates memory acquisition and consolidation in the mouse elevated T-maze.
Journal: Neuroscience letters 20050603
Title: Suppression of conditioned nicotine and sucrose seeking by the cannabinoid-1 receptor antagonist SR141716A.
Journal: Behavioural brain research 20050603
Title: Disruption of CB(1) receptor signaling impairs extinction of spatial memory in mice.
Journal: Psychopharmacology 20050601
Title: CB1 cannabinoid receptor-mediated modulation of food intake in mice.
Journal: British journal of pharmacology 20050601
Title: The effects of Delta9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide.
Journal: British journal of pharmacology 20050601
Title: Endocannabinoid release from midbrain dopamine neurons: a potential substrate for cannabinoid receptor antagonist treatment of addiction.
Journal: Neuropharmacology 20050601
Title: Cannabinoids produce neuroprotection by reducing intracellular calcium release from ryanodine-sensitive stores.
Journal: Neuropharmacology 20050601
Title: Cannabinoid CB(1) antagonist SR 141716A attenuates reinstatement of heroin self-administration in heroin-abstinent rats.
Journal: Neuropharmacology 20050601
Title: Peripheral, but not central effects of cannabidiol derivatives: mediation by CB(1) and unidentified receptors.
Journal: Neuropharmacology 20050601
Title: Evidence that (-)-7-hydroxy-4'-dimethylheptyl-cannabidiol activates a non-CB(1), non-CB(2), non-TRPV1 target in the mouse vas deferens.
Journal: Neuropharmacology 20050601
Title: CB1 receptor antagonists for the treatment of nicotine addiction.
Journal: Pharmacology, biochemistry, and behavior 20050601
Title: Intention to lose weight, weight changes, and 18-y mortality in overweight individuals without co-morbidities.
Journal: PLoS medicine 20050601
Title: Keynote review: Medicinal chemistry strategies to CB1 cannabinoid receptor antagonists.
Journal: Drug discovery today 20050515
Title: Interaction between gamma-aminobutyric acid GABAB and cannabinoid CB1 receptors in spinal pain pathways in rat.
Journal: European journal of pharmacology 20050509
Title: [Highlights from the American College of Cardiology Annual Scientific Session 2005: March 5-9, 2005, Orlando, Florida].
Journal: Revue medicale suisse 20050504
Title: Tricyclic pyrazoles. Part 2: Synthesis and biological evaluation of novel 4,5-dihydro-1H-benzo[g]indazole-based ligands for cannabinoid receptors.
Journal: Bioorganic & medicinal chemistry 20050502
Title: The cannabinoid CB1 receptor antagonist SR141716A reduces appetitive and consummatory responses for food.
Journal: Psychopharmacology 20050501
Title: CB1 cannabinoid receptor agonists increase intracranial self-stimulation thresholds in the rat.
Journal: Psychopharmacology 20050501
Title: Endocannabinoid control of food intake and energy balance.
Journal: Nature neuroscience 20050501
Title: Evidence for novel cannabinoid receptors.
Journal: Pharmacology & therapeutics 20050501
Title: The cannabinoid receptor agonist WIN 55212-2 inhibits neurogenic inflammations in airway tissues.
Journal: Journal of pharmacological sciences 20050501
Title: Cannabinoid receptor antagonists SR141716 and SR144528 exhibit properties of partial agonists in experiments on isolated perfused rat heart.
Journal: Bulletin of experimental biology and medicine 20050501
Title: Substituted 5,5'-diphenyl-2-thioxoimidazolidin-4-one as CB1 cannabinoid receptor ligands: synthesis and pharmacological evaluation.
Journal: Journal of medicinal chemistry 20050407
Title: Protective effects of Delta(9)-tetrahydrocannabinol against N-methyl-d-aspartate-induced AF5 cell death.
Journal: Brain research. Molecular brain research 20050404
Title: In vitro metabolism of diarylpyrazoles, a novel group of cannabinoid receptor ligands.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20050401
Title: Involvement of protein kinase A in cannabinoid receptor-mediated protection from oxidative neuronal injury.
Journal: The Journal of pharmacology and experimental therapeutics 20050401
Title: Cannabinoid CB1 antagonists possess antiparkinsonian efficacy only in rats with very severe nigral lesion in experimental parkinsonism.
Journal: Neurobiology of disease 20050401
Title: Rimonabant--a selective CB1 antagonist.
Journal: The Annals of pharmacotherapy 20050401
Title: [Innovation instead of imitation -- news in drug therapy].
Journal: Deutsche medizinische Wochenschrift (1946) 20050401
Title: Fighting obesity and associated risk factors by antagonising cannabinoid type 1 receptors.
Journal: Lancet (London, England) 20050401
Title: Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study.
Journal: Lancet (London, England) 20050401
Title: Obesity and cardiovascular physiology: impact of some pharmacological agents.
Journal: Current vascular pharmacology 20050401
Title: Cannabinoid CB1 receptor antagonism reduces conditioned reinstatement of ethanol-seeking behavior in rats.
Journal: The European journal of neuroscience 20050401
Title: Bioisosteric replacements of the pyrazole moiety of rimonabant: synthesis, biological properties, and molecular modeling investigations of thiazoles, triazoles, and imidazoles as potent and selective CB1 cannabinoid receptor antagonists.
Journal: Journal of medicinal chemistry 20050324
Title: [Blocking the endocannabinoid system -- weight reduction and cardiovascular risk management].
Journal: Deutsche medizinische Wochenschrift (1946) 20050324
Title: Involvement of cannabinoid receptors in the regulation of neurotransmitter release in the rodent striatum: a combined immunochemical and pharmacological analysis.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050316
Title: Effects of the endocannabinoid noladin ether on body weight, food consumption, locomotor activity, and cognitive index in mice.
Journal: Brain research bulletin 20050315
Title: Synergistic interactions between cannabinoids and environmental stress in the activation of the central amygdala.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050301
Title: Cannabinoid CB1 receptor antagonists as promising new medications for drug dependence.
Journal: The Journal of pharmacology and experimental therapeutics 20050301
Title: Enhancing cannabinoid neurotransmission augments the extinction of conditioned fear.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050301
Title: Pharmacological modulation of the endocannabinoid system in a viral model of multiple sclerosis.
Journal: Journal of neurochemistry 20050301
Title: Cannabinoid receptor as a novel target for the treatment of prostate cancer.
Journal: Cancer research 20050301
Title: Cannabinoids and the regulation of ingestive behaviour.
Journal: Current drug targets 20050301
Title: Will the new CB1 cannabinoid receptor antagonist SR-147778 have advantages over rimonabant?
Journal: Expert opinion on investigational drugs 20050301
Title: Inverse agonism and neutral antagonism at cannabinoid CB1 receptors.
Journal: Life sciences 20050204
Title: Effects of the cannabinoid CB1 receptor antagonist SR141716 on oxygen consumption and soleus muscle glucose uptake in Lep(ob)/Lep(ob) mice.
Journal: International journal of obesity (2005) 20050201
Title: Human sperm express cannabinoid receptor Cb1, the activation of which inhibits motility, acrosome reaction, and mitochondrial function.
Journal: The Journal of clinical endocrinology and metabolism 20050201
Title: 3,4 Methylenedioxymethamphetamine-induced conditioned place preference (CPP) is mediated by endocannabinoid system.
Journal: Pharmacological research 20050201
Title: The nonpsychoactive component of marijuana cannabidiol modulates chemotaxis and IL-10 and IL-12 production of murine macrophages both in vivo and in vitro.
Journal: Journal of neuroimmunology 20050201
Title: Synthesis and SAR of 5,6-diarylpyridines as human CB1 inverse agonists.
Journal: Bioorganic & medicinal chemistry letters 20050201
Title: Effects of the cannabinoid CB1 receptor antagonist rimonabant in models of emotional reactivity in rodents.
Journal: Biological psychiatry 20050201
Title: [Endocannabinoid and endocannabinoid receptor antagonists].
Journal: Medizinische Monatsschrift fur Pharmazeuten 20050201
Title: Another pill for weight reduction.
Journal: Clinical cardiology 20050201
Title: Inhibition of restraint stress-induced neural and behavioural activation by endogenous cannabinoid signalling.
Journal: The European journal of neuroscience 20050201
Title: New diet drug stirs high hopes. But can the pill, rimonabant, liver up to large expectations?
Journal: Heart advisor 20050201
Title: Synthetic cannabinoid WIN55,212-2 inhibits generation of inflammatory mediators by IL-1beta-stimulated human astrocytes.
Journal: Glia 20050115
Title: [Nutrition--obesity].
Journal: Revue medicale suisse 20050105
Title: Nicotine-associated cues maintain nicotine-seeking behavior in rats several weeks after nicotine withdrawal: reversal by the cannabinoid (CB1) receptor antagonist, rimonabant (SR141716).
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050101
Title: Role of the endocannabinoid system in the development of tolerance to alcohol.
Journal: Alcohol and alcoholism (Oxford, Oxfordshire) 20050101
Title: Interactions between cannabinoid and opioid receptor systems in the mediation of ethanol effects.
Journal: Alcohol and alcoholism (Oxford, Oxfordshire) 20050101
Title: Up-regulation of the endocannabinoid system in the uterus of leptin knockout (ob/ob) mice and implications for fertility.
Journal: Molecular human reproduction 20050101
Title: Endogenous cannabinoids are not involved in cocaine reinforcement and development of cocaine-induced behavioural sensitization.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20050101
Title: Suppressing effect of the cannabinoid CB1 receptor antagonist, SR147778, on alcohol intake and motivational properties of alcohol in alcohol-preferring sP rats.
Journal: Alcohol and alcoholism (Oxford, Oxfordshire) 20050101
Title: The anti-obesity effect of rimonabant is associated with an improved serum lipid profile.
Journal: Diabetes, obesity & metabolism 20050101
Title: Search for an endogenous cannabinoid-mediated effect in the sympathetic nervous system.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20050101
Title: Cannabis antagonists: a new era of social psychopharmacology?
Journal: Journal of psychopharmacology (Oxford, England) 20050101
Title: [The best of clinical pharmacology in 2004].
Journal: Archives des maladies du coeur et des vaisseaux 20050101
Title: [Endocannabinoids--the new option in the treatment of metabolic syndrome and in smoking cessation].
Journal: Casopis lekaru ceskych 20050101
Title: Cannabinoids depress excitatory neurotransmission between the subthalamic nucleus and the globus pallidus.
Journal: Neuroscience 20050101
Title: Periaqueductal grey CB1 cannabinoid and metabotropic glutamate subtype 5 receptors modulate changes in rostral ventromedial medulla neuronal activities induced by subcutaneous formalin in the rat.
Journal: Neuroscience 20050101
Title: Rimonabant: unique and promising.
Journal: Preventive cardiology 20050101
Title: [Obesity and type 2 diabetes].
Journal: Revue medicale de Liege 20050101
Title: [The endocannabinoid system and the regulation of the metabolism].
Journal: Revue medicale de Bruxelles 20050101
Title: [Rimonabant (Acomplia), specific inhibitor of the endocannabinoid system].
Journal: Revue medicale de Bruxelles 20050101
Title: Cocaine- and amphetamine-related transcript is involved in the orexigenic effect of endogenous anandamide.
Journal: Neuroendocrinology 20050101
Title: Pharmacotherapy for nicotine dependence.
Journal: CA: a cancer journal for clinicians 20050101
Title: Prevalence, predisposition and prevention of type II diabetes.
Journal: Nutrition & metabolism 20050101
Title: [The endocannabinoid system and the regulation of the metabolism].
Journal: Journal de pharmacie de Belgique 20050101
Title: [Rimonabant (Acomplia), specific inhibitor of the endocannabinoid system].
Journal: Journal de pharmacie de Belgique 20050101
Title: The endocannabinoid system: a new approach to control cardiovascular disease.
Journal: Clinical cornerstone 20050101
Title: The metabolic basis of atherogenic dyslipidemia.
Journal: Clinical cornerstone 20050101
Title: Managing cardiovascular risk inpatients with metabolic syndrome.
Journal: Clinical cornerstone 20050101
Title: Pharmacotherapy to reduce visceral fat.
Journal: Clinical cornerstone 20050101
Title: Cannabinoid tolerance and dependence.
Journal: Handbook of experimental pharmacology 20050101
Title: Human brain endothelium: coexpression and function of vanilloid and endocannabinoid receptors.
Journal: Brain research. Molecular brain research 20041206
Title: Delta9-tetrahydrocannabinol-induced conditioned place preference and intracerebroventricular self-administration in rats.
Journal: European journal of pharmacology 20041203
Title: Discriminative stimulus effects in rats of SR-141716 (rimonabant), a cannabinoid CB1 receptor antagonist.
Journal: Psychopharmacology 20041201
Title: Activation of cannabinoid CB2 receptors suppresses C-fiber responses and windup in spinal wide dynamic range neurons in the absence and presence of inflammation.
Journal: Journal of neurophysiology 20041201
Title: Modulation of morphine-induced Fos-immunoreactivity by the cannabinoid receptor antagonist SR 141716.
Journal: Neuropharmacology 20041201
Title: The weight debate, continued.
Journal: Managed care (Langhorne, Pa.) 20041201
Title: (S)-AMPA inhibits electrically evoked calcitonin gene-related peptide (CGRP) release from the rat dorsal horn: reversal by cannabinoid receptor antagonist SR141716A.
Journal: Neuroscience letters 20041130
Title: Discriminative stimulus effects of the structurally novel cannabinoid CB1/CB2 receptor partial agonist BAY 59-3074 in the rat.
Journal: European journal of pharmacology 20041128
Title: A cannabinoid receptor antagonist attenuates conditioned place preference but not behavioural sensitization to morphine.
Journal: Brain research 20041112
Title: [Endocannabinoids receptor blocker lets tumble not only money. A drug against metabolic syndrome?].
Journal: MMW Fortschritte der Medizin 20041104
Title: Endocannabinoids link feeding state and auditory perception-related gene expression.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20041103
Title: Cannabinoid receptor agonists inhibit sensory nerve activation in guinea pig airways.
Journal: American journal of respiratory and critical care medicine 20041101
Title: The cannabinoid CB1 receptor antagonist SR141716 blocks the orexigenic effects of intrahypothalamic ghrelin.
Journal: British journal of pharmacology 20041101
Title: (-)-Adamantyl-delta8-tetrahydrocannabinol (AM-411), a selective cannabinoid CB1 receptor agonist: effects on open-field behaviors and antagonism by SR-141716 in rats.
Journal: Behavioural pharmacology 20041101
Title: Cannabinoid CB2 receptor activation inhibits mechanically evoked responses of wide dynamic range dorsal horn neurons in naïve rats and in rat models of inflammatory and neuropathic pain.
Journal: The European journal of neuroscience 20041101
Title: Potential modulation of plasma ghrelin and glucagon-like peptide-1 by anorexigenic cannabinoid compounds, SR141716A (rimonabant) and oleoylethanolamide.
Journal: The British journal of nutrition 20041101
Title: Cannabidiol prevents infarction via the non-CB1 cannabinoid receptor mechanism.
Journal: Neuroreport 20041025
Title: Cannabinoid inhibition improves memory in food-storing birds, but with a cost.
Journal: Proceedings. Biological sciences 20041007
Title: Cannabinoid receptor antagonist reduces heroin self-administration only in dependent rats.
Journal: European journal of pharmacology 20041006
Title: Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension.
Journal: Circulation 20041005
Title: Characterization of cannabinoid modulation of sensory neurotransmission in the rat isolated mesenteric arterial bed.
Journal: The Journal of pharmacology and experimental therapeutics 20041001
Title: The THC-induced suppression of Th1 polarization in response to Legionella pneumophila infection is not mediated by increases in corticosterone and PGE2.
Journal: Journal of leukocyte biology 20041001
Title: A new strategy to block tumor growth by inhibiting endocannabinoid inactivation.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20041001
Title: CB1 receptor agonist and heroin, but not cocaine, reinstate cannabinoid-seeking behaviour in the rat.
Journal: British journal of pharmacology 20041001
Title: Changes in endocannabinoid levels in a rat model of behavioural sensitization to morphine.
Journal: The European journal of neuroscience 20041001
Title: Clinical pharmacotherapy for obesity: current drugs and those in advanced development.
Journal: Current drug targets 20041001
Title: Rimonabant, a CB1 antagonist, blocks nicotine-conditioned place preferences.
Journal: Neuroreport 20040915
Title: Suppressing effect of the cannabinoid CB1 receptor antagonist, SR 141716, on alcohol's motivational properties in alcohol-preferring rats.
Journal: European journal of pharmacology 20040913
Title: Analysis of the effects of cannabinoids on synaptic transmission between basket and Purkinje cells in the cerebellar cortex of the rat.
Journal: The Journal of pharmacology and experimental therapeutics 20040901
Title: Effect of low doses of delta9-tetrahydrocannabinol and cannabidiol on the extinction of cocaine-induced and amphetamine-induced conditioned place preference learning in rats.
Journal: Psychopharmacology 20040901
Title: Vanilloid TRPV1 receptor mediates the antihyperalgesic effect of the nonpsychoactive cannabinoid, cannabidiol, in a rat model of acute inflammation.
Journal: British journal of pharmacology 20040901
Title: 3-Morpholinylsydnonimine inhibits glutamatergic transmission in rat rostral ventrolateral medulla via peroxynitrite formation and adenosine release.
Journal: Molecular pharmacology 20040901
Title: Rats on the grog: novel pharmacotherapies for alcohol craving.
Journal: Addictive behaviors 20040901
Title: Evidence for an interaction between CB1 cannabinoid and oxytocin receptors in food and water intake.
Journal: Neuropharmacology 20040901
Title: Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas.
Journal: Cancer research 20040815
Title: Anandamide transport inhibitor AM404 and structurally related compounds inhibit synaptic transmission between rat hippocampal neurons in culture independent of cannabinoid CB1 receptors.
Journal: European journal of pharmacology 20040802
Title: Cannabinoid antagonist SR-141716 inhibits endotoxic hypotension by a cardiac mechanism not involving CB1 or CB2 receptors.
Journal: American journal of physiology. Heart and circulatory physiology 20040801
Title: Endocannabinoid system modulates relapse to methamphetamine seeking: possible mediation by the arachidonic acid cascade.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040801
Title: Evidence for differential modulation of conditioned aversion and fear-conditioned analgesia by CB1 receptors.
Journal: The European journal of neuroscience 20040801
Title: Role of different brain structures in the behavioural expression of WIN 55,212-2 withdrawal in mice.
Journal: British journal of pharmacology 20040801
Title: A comparison of the discriminative stimulus effects of delta(9)-tetrahydrocannabinol and O-1812, a potent and metabolically stable anandamide analog, in rats.
Journal: Experimental and clinical psychopharmacology 20040801
Title: Genetic deletion and pharmacological blockade of CB1 receptors modulates anxiety in the shock-probe burying test.
Journal: The European journal of neuroscience 20040801
Title: Current and investigational antiobesity agents and obesity therapeutic treatment targets.
Journal: Obesity research 20040801
Title: Adolescent exposure to cannabinoids induces long-lasting changes in the response to drugs of abuse of rat midbrain dopamine neurons.
Journal: Biological psychiatry 20040715
Title: A comparative analysis of the potential of cannabinoids and ondansetron to suppress cisplatin-induced emesis in the Suncus murinus (house musk shrew).
Journal: Psychopharmacology 20040701
Title: Evidence for an interaction between CB1 cannabinoid and melanocortin MCR-4 receptors in regulating food intake.
Journal: Endocrinology 20040701
Title: Effects on turning of microinjections into basal ganglia of D(1) and D(2) dopamine receptors agonists and the cannabinoid CB(1) antagonist SR141716A in a rat Parkinson's model.
Journal: Neurobiology of disease 20040701
Title: Central effects of the cannabinoid receptor agonist WIN55212-2 on respiratory and cardiovascular regulation in anaesthetised rats.
Journal: British journal of pharmacology 20040701
Title: TRPV1 and CB(1) receptor-mediated effects of the endovanilloid/endocannabinoid N-arachidonoyl-dopamine on primary afferent fibre and spinal cord neuronal responses in the rat.
Journal: The European journal of neuroscience 20040701
Title: Inhibitory effect of the antidepressant St. John's wort (hypericum perforatum) on rat bladder contractility in vitro.
Journal: Urology 20040701
Title: CB1 cannabinoid receptors mediate anxiolytic effects: convergent genetic and pharmacological evidence with CB1-specific agents.
Journal: Behavioural pharmacology 20040701
Title: Recent advances in CB1 cannabinoid receptor antagonists.
Journal: Current opinion in drug discovery & development 20040701
Title: Comparison of anandamide transport in FAAH wild-type and knockout neurons: evidence for contributions by both FAAH and the CB1 receptor to anandamide uptake.
Journal: Biochemistry 20040629
Title: Rapid tolerance to the intestinal prokinetic effect of cannabinoid CB1 receptor antagonist, SR 141716 (Rimonabant).
Journal: European journal of pharmacology 20040628
Title: The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat.
Journal: European journal of pharmacology 20040616
Title: Sex-linked differences in the vasorelaxant effects of anandamide in vascular mesenteric beds: role of oestrogens.
Journal: European journal of pharmacology 20040616
Title: Cannabinoid agonist-induced sensitisation to morphine place preference in mice.
Journal: Neuroreport 20040607
Title: Cannabinoids enhance N-methyl-D-aspartate-induced excitation of locus coeruleus neurons by CB1 receptors in rat brain slices.
Journal: Neuroscience letters 20040603
Title: Cannabinoids prevent the acute hyperthermia and partially protect against the 5-HT depleting effects of MDMA ('Ecstasy') in rats.
Journal: Neuropharmacology 20040601
Title: Presynaptic cannabinoid CB(1) receptors are involved in the inhibition of the neurogenic vasopressor response during septic shock in pithed rats.
Journal: British journal of pharmacology 20040601
Title: Placebo-controlled evaluation of four novel compounds for the treatment of schizophrenia and schizoaffective disorder.
Journal: The American journal of psychiatry 20040601
Title: Clinical trials update and cumulative meta-analyses from the American College of Cardiology: WATCH, SCD-HeFT, DINAMIT, CASINO, INSPIRE, STRATUS-US, RIO-Lipids and cardiac resynchronisation therapy in heart failure.
Journal: European journal of heart failure 20040601
Title: Multiple sclerosis following treatment with a cannabinoid receptor-1 antagonist.
Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20040601
Title: Memory reconsolidation and extinction have distinct temporal and biochemical signatures.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040519
Title: Behavioral and molecular changes elicited by acute administration of SR141716 to Delta9-tetrahydrocannabinol-tolerant rats: an experimental model of cannabinoid abstinence.
Journal: Drug and alcohol dependence 20040510
Title: Cannabinoids enhance subsecond dopamine release in the nucleus accumbens of awake rats.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040505
Title: Blockade by the cannabinoid CB1 receptor antagonist, rimonabant (SR141716), of the potentiation by quinelorane of food-primed reinstatement of food-seeking behavior.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040501
Title: Cannabinoid receptor-mediated regulation of intracellular calcium by delta(9)-tetrahydrocannabinol in resting T cells.
Journal: Journal of leukocyte biology 20040501
Title: Retrograde activation of presynaptic NMDA receptors enhances GABA release at cerebellar interneuron-Purkinje cell synapses.
Journal: Nature neuroscience 20040501
Title: Advances in pharmacotherapy for tobacco dependence.
Journal: Expert opinion on emerging drugs 20040501
Title: The endogenous cannabinoid system protects against colonic inflammation.
Journal: The Journal of clinical investigation 20040415
Title: Antagonism of cannabinoid CB1 receptors in the paraventricular nucleus of male rats induces penile erection.
Journal: Neuroscience letters 20040408
Title: Combined low dose treatment with opioid and cannabinoid receptor antagonists synergistically reduces the motivation to consume alcohol in rats.
Journal: Psychopharmacology 20040401
Title: Differential effects of delta9-tetrahydrocannabinol and methanandamide in CB1 knockout and wild-type mice.
Journal: The Journal of pharmacology and experimental therapeutics 20040401
Title: CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity.
Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20040401
Title: Multiple actions of anandamide on neonatal rat cultured sensory neurones.
Journal: British journal of pharmacology 20040401
Title: Treating obesity: pharmacology of energy expenditure.
Journal: Current drug targets 20040401
Title: Involvement of brain-derived neurotrophic factor in cannabinoid receptor-dependent protection against excitotoxicity.
Journal: The European journal of neuroscience 20040401
Title: Very low doses of delta 8-THC increase food consumption and alter neurotransmitter levels following weight loss.
Journal: Pharmacology, biochemistry, and behavior 20040401
Title: The effect of SR 141716 and apomorphine on sensorimotor gating in Swiss mice.
Journal: Pharmacology, biochemistry, and behavior 20040401
Title: Cannabinoid receptor antagonists and obesity.
Journal: Current opinion in investigational drugs (London, England : 2000) 20040401
Title: Rimonabant Sanofi-Synthélabo.
Journal: Current opinion in investigational drugs (London, England : 2000) 20040401
Title: [A new pill for metabolic syndrome. Successful control of lipids, kilos and cigarettes].
Journal: MMW Fortschritte der Medizin 20040325
Title: Central and peripheral mechanisms contribute to the antiemetic actions of delta-9-tetrahydrocannabinol against 5-hydroxytryptophan-induced emesis.
Journal: European journal of pharmacology 20040319
Title: Potent imidazole and triazole CB1 receptor antagonists related to SR141716.
Journal: Bioorganic & medicinal chemistry letters 20040308
Title: [Blocking cannabinoid receptors. Simultaneous control of overweight and nicotine addiction].
Journal: MMW Fortschritte der Medizin 20040304
Title: Selective antagonist [3H]SR141716A binding to cannabinoid CB1 receptors is increased in the anterior cingulate cortex in schizophrenia.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20040301
Title: Massive accumulation of N-acylethanolamines after stroke. Cell signalling in acute cerebral ischemia?
Journal: Journal of neurochemistry 20040301
Title: Amyotrophic lateral sclerosis: delayed disease progression in mice by treatment with a cannabinoid.
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20040301
Title: Disruption of endocannabinoid release and striatal long-term depression by postsynaptic blockade of endocannabinoid membrane transport.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040218
Title: Selective activation of cannabinoid CB2 receptors suppresses hyperalgesia evoked by intradermal capsaicin.
Journal: The Journal of pharmacology and experimental therapeutics 20040201
Title: Cannabinoids modulate ultrasound-induced aversive responses in rats.
Journal: Psychopharmacology 20040201
Title: Cannabinoid receptors and T helper cells.
Journal: Journal of neuroimmunology 20040201
Title: CB(1) receptor mediation of cannabinoid behavioral effects in male and female rats.
Journal: Psychopharmacology 20040201
Title: Partial agonist-like profile of the cannabinoid receptor antagonist SR141716A in a food-reinforced operant paradigm.
Journal: Behavioural pharmacology 20040201
Title: Differential effects of the sleep-inducing lipid oleamide and cannabinoids on the induction of long-term potentiation in the CA1 neurons of the rat hippocampus in vitro.
Journal: Brain research 20040130
Title: Synthesis, biological properties, and molecular modeling investigations of novel 3,4-diarylpyrazolines as potent and selective CB(1) cannabinoid receptor antagonists.
Journal: Journal of medicinal chemistry 20040129
Title: Consumption of high carbohydrate, high fat, and normal chow is equally suppressed by a cannabinoid receptor antagonist in non-deprived rats.
Journal: Neuroscience letters 20040116
Title: Cannabinoid receptor type 1 modulates excitatory and inhibitory neurotransmission in mouse colon.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20040101
Title: Corticotropin-releasing hormone (CRH) mRNA expression in rat central amygdala in cannabinoid tolerance and withdrawal: evidence for an allostatic shift?
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040101
Title: Effect of cannabinoids on lithium-induced vomiting in the Suncus murinus (house musk shrew).
Journal: Psychopharmacology 20040101
Title: Behavioral mechanisms underlying inhibition of food-maintained responding by the cannabinoid receptor antagonist/inverse agonist SR141716A.
Journal: European journal of pharmacology 20040101
Title: Cannabinoids and the human uterus during pregnancy.
Journal: American journal of obstetrics and gynecology 20040101
Title: Long-term effects on cortical glutamate release induced by prenatal exposure to the cannabinoid receptor agonist (R)-(+)-[2,3-dihydro-5-methyl-3-(4-morpholinyl-methyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenylmethanone: an in vivo microdialysis study in the awake rat.
Journal: Neuroscience 20040101
Title: Neurokinin B, neurotensin, and cannabinoid receptor antagonists and Parkinson disease.
Journal: Clinical neuropharmacology 20040101
Title: Molecule of the month. Rimonabant hydrochloride.
Journal: Drug news & perspectives 20040101
Title: Cannabinoid physiology and pharmacology: 30 years of progress.
Journal: Neuropharmacology 20040101
Title: Effects of CB1 cannabinoid receptor blockade on ethanol preference after chronic alcohol administration combined with repeated re-exposures and withdrawals.
Journal: Alcohol and alcoholism (Oxford, Oxfordshire) 20040101
Title: Anandamide content is increased and CB1 cannabinoid receptor blockade is protective during transient, focal cerebral ischemia.
Journal: Neuroscience 20040101
Title: Enhancement of androgen receptor expression induced by (R)-methanandamide in prostate LNCaP cells.
Journal: FEBS letters 20031218
Title: Cannabinoids decrease corticostriatal synaptic transmission via an effect on glutamate uptake.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20031203
Title: An optimized approach to study endocannabinoid signaling: evidence against constitutive activity of rat brain adenosine A1 and cannabinoid CB1 receptors.
Journal: British journal of pharmacology 20031201
Title: A novel neuroimmune mechanism in cannabinoid-mediated attenuation of nerve growth factor-induced hyperalgesia.
Journal: Anesthesiology 20031201
Title: SR141716A reduces the reinforcing properties of heroin but not heroin-induced increases in nucleus accumbens dopamine in rats.
Journal: The European journal of neuroscience 20031201
Title: The cannabinoid CB1 antagonists SR 141716A and AM 251 suppress food intake and food-reinforced behavior in a variety of tasks in rats.
Journal: Behavioural pharmacology 20031201
Title: An aromatic microdomain at the cannabinoid CB(1) receptor constitutes an agonist/inverse agonist binding region.
Journal: Journal of medicinal chemistry 20031120
Title: Antagonism between the anti-inflammatory activity of the cannabinoid WIN 55212-2 and SR 141716A.
Journal: Pharmacology 20031101
Title: Discriminative stimulus effects of the cannabinoid antagonist, SR 141716A, in delta -sup-9-tetrahydrocannabinol-treated rhesus monkeys.
Journal: Experimental and clinical psychopharmacology 20031101
Title: Biphasic effects of cannabinoids on acetylcholine release in the hippocampus: site and mechanism of action.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20031015
Title: CB1 cannabinoid receptors and on-demand defense against excitotoxicity.
Journal: Science (New York, N.Y.) 20031003
Title: Effects of direct periaqueductal grey administration of a cannabinoid receptor agonist on nociceptive and aversive responses in rats.
Journal: Neuropharmacology 20031001
Title: The endogenous cannabinoid system regulates seizure frequency and duration in a model of temporal lobe epilepsy.
Journal: The Journal of pharmacology and experimental therapeutics 20031001
Title: Hypotensive effect of anandamide through the activation of CB1 and VR1 spinal receptors in urethane-anesthetized rats.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20031001
Title: Activation of peripheral cannabinoid CB1 receptors inhibits mechanically evoked responses of spinal neurons in noninflamed rats and rats with hindpaw inflammation.
Journal: The European journal of neuroscience 20031001
Title: Cannabinoids inhibit the release of [3H]glutamate from rodent hippocampal synaptosomes via a novel CB1 receptor-independent action.
Journal: The European journal of neuroscience 20031001
Title: Antagonizing the cannabinoid receptor type 1: a dual way to fight obesity.
Journal: Journal of endocrinological investigation 20031001
Title: Potentiation of penile erection and yawning responses to apomorphine by cannabinoid receptor antagonist in rats.
Journal: Neuroscience letters 20030925
Title: SR141716A, a cannabinoid CB1 receptor antagonist, improves memory in a delayed radial maze task.
Journal: European journal of pharmacology 20030923
Title: Amnesia induced by beta-amyloid fragments is counteracted by cannabinoid CB1 receptor blockade.
Journal: European journal of pharmacology 20030923
Title: Inhibitory effect of anandamide on resiniferatoxin-induced sensory neuropeptide release in vivo and neuropathic hyperalgesia in the rat.
Journal: Life sciences 20030919
Title: Cannabinoid modulation of sensitivity to time.
Journal: Behavioural brain research 20030915
Title: Activation of phosphoinositide 3-kinase/PKB pathway by CB(1) and CB(2) cannabinoid receptors expressed in prostate PC-3 cells. Involvement in Raf-1 stimulation and NGF induction.
Journal: Cellular signalling 20030901
Title: Role of cannabinoid CB1 receptors and tumor necrosis factor-alpha in the gut and systemic anti-inflammatory activity of SR 141716 (rimonabant) in rodents.
Journal: British journal of pharmacology 20030901
Title: Lack of CB1 receptors increases noradrenaline release in vas deferens without affecting atrial noradrenaline release or cortical acetylcholine release.
Journal: British journal of pharmacology 20030901
Title: Inhibition of guinea-pig and human sensory nerve activity and the cough reflex in guinea-pigs by cannabinoid (CB2) receptor activation.
Journal: British journal of pharmacology 20030901
Title: Effects of levodopa on endocannabinoid levels in rat basal ganglia: implications for the treatment of levodopa-induced dyskinesias.
Journal: The European journal of neuroscience 20030901
Title: Effects of cannabinoids on non-adrenergic non-cholinergic-mediated relaxation in guinea-pig trachea.
Journal: European journal of pharmacology 20030815
Title: Arachidonylcyclopropylamide increases microglial cell migration through cannabinoid CB2 and abnormal-cannabidiol-sensitive receptors.
Journal: European journal of pharmacology 20030808
Title: Antitussive effect of WIN 55212-2, a cannabinoid receptor agonist.
Journal: European journal of pharmacology 20030808
Title: Functional localization of cannabinoid receptors and endogenous cannabinoid production in distinct neuron populations of the hippocampus.
Journal: The European journal of neuroscience 20030801
Title: Endogenous interleukin-1 receptor antagonist mediates anti-inflammatory and neuroprotective actions of cannabinoids in neurons and glia.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030723
Title: The effect of cannabinoid receptor antagonism with SR141716A on antinociception induced by cocaine and the NMDA receptor antagonist, MK-801.
Journal: Brain research bulletin 20030715
Title: The cannabinoid CB1 antagonist N-piperidinyl-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl) -4-methylpyrazole-3-carboxamide (SR-141716A) differentially alters the reinforcing effects of heroin under continuous reinforcement, fixed ratio, and progressive ratio schedules of drug self-administration in rats.
Journal: The Journal of pharmacology and experimental therapeutics 20030701
Title: Synthesis and characterization of NESS 0327: a novel putative antagonist of the CB1 cannabinoid receptor.
Journal: The Journal of pharmacology and experimental therapeutics 20030701
Title: The cannabinoid receptor antagonist SR 141716 attenuates overfeeding induced by systemic or intracranial morphine.
Journal: Psychopharmacology 20030701
Title: Anxiety does not affect the antinociceptive effect of Delta 9-THC in mice: participation of cannabinoid and opioid receptors.
Journal: Pharmacology, biochemistry, and behavior 20030701
Title: Behaviorally active doses of the CB1 receptor antagonist SR 141716A increase brain serotonin and dopamine levels and turnover.
Journal: Pharmacology, biochemistry, and behavior 20030701
Title: The cannabinoid receptor antagonist SR-141716 does not readily antagonize open-field effects induced by the cannabinoid receptor agonist (R)-methanandamide in rats.
Journal: Pharmacology, biochemistry, and behavior 20030701
Title: Hypersensitization of the Orexin 1 receptor by the CB1 receptor: evidence for cross-talk blocked by the specific CB1 antagonist, SR141716.
Journal: The Journal of biological chemistry 20030627
Title: Cannabinoid pharmacological properties common to other centrally acting drugs.
Journal: European journal of pharmacology 20030627
Title: Functional tolerance and blockade of long-term depression at synapses in the nucleus accumbens after chronic cannabinoid exposure.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030615
Title: Overeating, alcohol and sucrose consumption decrease in CB1 receptor deleted mice.
Journal: Neuroscience letters 20030612
Title: Neuroprotection by the cannabinoid agonist WIN-55212 in an in vivo newborn rat model of acute severe asphyxia.
Journal: Brain research. Molecular brain research 20030610
Title: Subversion and utilization of the host cell cyclic adenosine 5'-monophosphate/protein kinase A pathway by Brucella during macrophage infection.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030601
Title: Reduction of human monocytic cell neurotoxicity and cytokine secretion by ligands of the cannabinoid-type CB2 receptor.
Journal: British journal of pharmacology 20030601
Title: Endocannabinoids protect the rat isolated heart against ischaemia.
Journal: British journal of pharmacology 20030601
Title: Anandamide regulates neuropeptide release from capsaicin-sensitive primary sensory neurons by activating both the cannabinoid 1 receptor and the vanilloid receptor 1 in vitro.
Journal: The European journal of neuroscience 20030601
Title: WIN 55,212-2 decreases the reinforcing actions of cocaine through CB1 cannabinoid receptor stimulation.
Journal: Behavioural brain research 20030515
Title: Integrity of extracellular loop 1 of the human cannabinoid receptor 1 is critical for high-affinity binding of the ligand CP 55,940 but not SR 141716A.
Journal: Biochemical pharmacology 20030515
Title: Effects of cannabinoids in the rat model of Huntington's disease generated by an intrastriatal injection of malonate.
Journal: Neuroreport 20030506
Title: Microinjection of a cannabinoid receptor antagonist into the NTS increases baroreflex duration in dogs.
Journal: American journal of physiology. Heart and circulatory physiology 20030501
Title: The peripheral sympathetic nervous system is the major target of cannabinoids in eliciting cardiovascular depression.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20030501
Title: Cannabinoid receptor activation differentially modulates ion channels in photoreceptors of the tiger salamander.
Journal: Journal of neurophysiology 20030501
Title: A cannabinoid agonist differentially attenuates deep tissue hyperalgesia in animal models of cancer and inflammatory muscle pain.
Journal: Pain 20030501
Title: (R)-Methanandamide and delta9-tetrahydrocannabinol-induced operant rate decreases in rats are not readily antagonized by SR-141716A.
Journal: European journal of pharmacology 20030411
Title: Experimental drugs take aim at obesity.
Journal: JAMA 20030409
Title: Preferential effects of the cannabinoid CB1 receptor antagonist, SR 141716, on food intake and body weight gain of obese (fa/fa) compared to lean Zucker rats.
Journal: Psychopharmacology 20030401
Title: The cannabinoid CB1 receptor antagonist SR141716 increases Acrp30 mRNA expression in adipose tissue of obese fa/fa rats and in cultured adipocyte cells.
Journal: Molecular pharmacology 20030401
Title: Differential cannabinoid-induced electrophysiological effects in rat ventral tegmentum.
Journal: Neuropharmacology 20030401
Title: Vasodilator actions of abnormal-cannabidiol in rat isolated small mesenteric artery.
Journal: British journal of pharmacology 20030401
Title: Cannabinoid mechanism in reinstatement of heroin-seeking after a long period of abstinence in rats.
Journal: The European journal of neuroscience 20030401
Title: Pre-exposure to the cannabinoid receptor agonist CP 55940 enhances morphine behavioral sensitization and alters morphine self-administration in Lewis rats.
Journal: European journal of pharmacology 20030328
Title: Pharmacological characterisation of cannabinoid receptors inhibiting interleukin 2 release from human peripheral blood mononuclear cells.
Journal: European journal of pharmacology 20030319
Title: Regulation of extracellular signal-regulated kinase by cannabinoids in hippocampus.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030315
Title: Prostaglandin E2 attenuates SR141716A-precipitated withdrawal in tetrahydrocannabinol-dependent mice.
Journal: Brain research 20030314
Title: Cannabinoids inhibit gap junctional intercellular communication and activate ERK in a rat liver epithelial cell line.
Journal: International journal of cancer 20030310
Title: Contribution of endocannabinoids in the endothelial protection afforded by ischemic preconditioning in the isolated rat heart.
Journal: Life sciences 20030307
Title: Effects of cannabinoids on lithium-induced conditioned rejection reactions in a rat model of nausea.
Journal: Psychopharmacology 20030301
Title: Compounds acting at the endocannabinoid and/or endovanilloid systems reduce hyperkinesia in a rat model of Huntington's disease.
Journal: Journal of neurochemistry 20030301
Title: Anandamide-induced depressor effect in spontaneously hypertensive rats: role of the vanilloid receptor.
Journal: Hypertension (Dallas, Tex. : 1979) 20030301
Title: Cannabinoid receptor-independent inhibition by cannabinoid agonists of the peripheral 5-HT3 receptor-mediated von Bezold-Jarisch reflex.
Journal: British journal of pharmacology 20030301
Title: Direct and indirect interactions between cannabinoid CB1 receptor and group II metabotropic glutamate receptor signalling in layer V pyramidal neurons from the rat prefrontal cortex.
Journal: The European journal of neuroscience 20030301
Title: 'One-trial sensitization' to the anxiolytic-like effects of cannabinoid receptor antagonist SR141716A in the mouse elevated plus-maze.
Journal: The European journal of neuroscience 20030301
Title: Cannabinoid-induced Fos expression within A10 dopaminergic neurons.
Journal: Brain research 20030214
Title: Synthesis, structure-activity relationship, and evaluation of SR141716 analogues: development of central cannabinoid receptor ligands with lower lipophilicity.
Journal: Journal of medicinal chemistry 20030213
Title: Functional consequences of the acute administration of the cannabinoid receptor antagonist, SR141716A, in cannabinoid-naive and -tolerant animals: a quantitative 2-[14C]deoxyglucose study.
Journal: Brain research 20030207
Title: Milk intake and survival in newborn cannabinoid CB1 receptor knockout mice: evidence for a 'CB3' receptor.
Journal: European journal of pharmacology 20030207
Title: Anti-obesity effect of SR141716, a CB1 receptor antagonist, in diet-induced obese mice.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20030201
Title: Cannabinoid influences on palatability: microstructural analysis of sucrose drinking after delta(9)-tetrahydrocannabinol, anandamide, 2-arachidonoyl glycerol and SR141716.
Journal: Psychopharmacology 20030201
Title: Endogenous cannabinoids: a new target in the treatment of obesity.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20030201
Title: Endocannabinoids induce ileitis in rats via the capsaicin receptor (VR1).
Journal: The Journal of pharmacology and experimental therapeutics 20030201
Title: Effects of CB1 cannabinoid receptor modulating compounds on the hyperkinesia induced by high-dose levodopa in the reserpine-treated rat model of Parkinson's disease.
Journal: Movement disorders : official journal of the Movement Disorder Society 20030201
Title: Activation of capsaicin-sensitive primary sensory neurones induces anandamide production and release.
Journal: Journal of neurochemistry 20030201
Title: The CB1 receptor antagonist SR141716A selectively increases monoaminergic neurotransmission in the medial prefrontal cortex: implications for therapeutic actions.
Journal: British journal of pharmacology 20030201
Title: Tricyclic pyrazoles. Part 1: synthesis and biological evaluation of novel 1,4-dihydroindeno[1,2-c]pyrazol-based ligands for CB1and CB2 cannabinoid receptors.
Journal: Bioorganic & medicinal chemistry 20030117
Title: The effects of delta9-tetrahydrocannabinol physical dependence on brain cannabinoid receptors.
Journal: European journal of pharmacology 20030117
Title: Concentration-dependent dual effect of anandamide on sensory neuropeptide release from isolated rat tracheae.
Journal: Neuroscience letters 20030116
Title: Cannabinoids ablate release of TNFalpha in rat microglial cells stimulated with lypopolysaccharide.
Journal: Glia 20030115
Title: R+-methanandamide inhibits tracheal response to endogenously released acetylcholine via capsazepine-sensitive receptors.
Journal: European journal of pharmacology 20030110
Title: Antiemetic and motor-depressive actions of CP55,940: cannabinoid CB1 receptor characterization, distribution, and G-protein activation.
Journal: European journal of pharmacology 20030110
Title: Differential distribution of functional cannabinoid CB1 receptors in the mouse gastroenteric tract.
Journal: European journal of pharmacology 20030110
Title: Effects of cannabinoid receptor ligands on psychosis-relevant behavior models in the rat.
Journal: Psychopharmacology 20030101
Title: Modulation of anxiety through blockade of anandamide hydrolysis.
Journal: Nature medicine 20030101
Title: Inhibition of interleukin-8 release in the human colonic epithelial cell line HT-29 by cannabinoids.
Journal: European journal of pharmacology 20030101
Title: A peripheral cannabinoid mechanism suppresses spinal fos protein expression and pain behavior in a rat model of inflammation.
Journal: Neuroscience 20030101
Title: Selective activation of cannabinoid CB(2) receptors suppresses spinal fos protein expression and pain behavior in a rat model of inflammation.
Journal: Neuroscience 20030101
Title: Pharmacophores for ligand recognition and activation/inactivation of the cannabinoid receptors.
Journal: Current pharmaceutical design 20030101
Title: Modulation of electrically evoked acetylcholine release through cannabinoid CB1 receptors: evidence for an endocannabinoid tone in the human neocortex.
Journal: Neuroscience 20030101
Title: Potential role of the cannabinoid receptor CB1 in rapid eye movement sleep rebound.
Journal: Neuroscience 20030101
Title: Tolerance to the memory disruptive effects of cannabinoids involves adaptation by hippocampal neurons.
Journal: Hippocampus 20030101
Title: Cannabinoid agonists and antagonists modulate lithium-induced conditioned gaping in rats.
Journal: Integrative physiological and behavioral science : the official journal of the Pavlovian Society 20030101
Title: In vivo imaging of the brain cannabinoid receptor.
Journal: Chemistry and physics of lipids 20021231
Title: Discriminative stimulus effects of BAY 38-7271, a novel cannabinoid receptor agonist.
Journal: European journal of pharmacology 20021220
Title: Endogenous cannabinoid, anandamide, acts as a noncompetitive inhibitor on 5-HT3 receptor-mediated responses in Xenopus oocytes.
Journal: Synapse (New York, N.Y.) 20021201
Title: SR-141716A-induced stimulation of locomotor activity. A structure-activity relationship study.
Journal: Pharmacology, biochemistry, and behavior 20021201
Title: Tolerance to the disruptive effects of Delta(9)-THC on learning in rats.
Journal: Pharmacology, biochemistry, and behavior 20021201
Title: The endocannabinoid system and the molecular basis of paralytic ileus in mice.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021201
Title: N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A) interaction with LYS 3.28(192) is crucial for its inverse agonism at the cannabinoid CB1 receptor.
Journal: Molecular pharmacology 20021201
Title: Design, expression, and characterization of a synthetic human cannabinoid receptor and cannabinoid receptor/ G-protein fusion protein.
Journal: The journal of peptide research : official journal of the American Peptide Society 20021201
Title: Effects of pharmacological manipulations of cannabinoid receptors on severity of dystonia in a genetic model of paroxysmal dyskinesia.
Journal: European journal of pharmacology 20021115
Title: Interactions between the CB1 receptor agonist Delta 9-THC and the CB1 receptor antagonist SR-141716 in rats: open-field revisited.
Journal: Pharmacology, biochemistry, and behavior 20021101
Title: Anandamide induces cough in conscious guinea-pigs through VR1 receptors.
Journal: British journal of pharmacology 20021101
Title: A peripheral mechanism for CB1 cannabinoid receptor-dependent modulation of feeding.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20021101
Title: Evidence for a physiological role of endocannabinoids in the modulation of seizure threshold and severity.
Journal: European journal of pharmacology 20021011
Title: Effect of chronic administration of R-(+)-[2,3-Dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo[1,2,3-de]-1,4-benzoxazinyl]-(1-naphthalenyl)methanone mesylate (WIN55,212-2) or delta(9)-tetrahydrocannabinol on cannabinoid receptor adaptation in mice.
Journal: The Journal of pharmacology and experimental therapeutics 20021001
Title: Inhibition of improgan antinociception by the cannabinoid (CB)(1) antagonist N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A): lack of obligatory role for endocannabinoids acting at CB(1) receptors.
Journal: The Journal of pharmacology and experimental therapeutics 20021001
Title: Cannabinoid receptor agonism inhibits transient lower esophageal sphincter relaxations and reflux in dogs.
Journal: Gastroenterology 20021001
Title: The effects of genetic and pharmacological blockade of the CB1 cannabinoid receptor on anxiety.
Journal: The European journal of neuroscience 20021001
Title: Delta(9)-tetrahydrocannabinol decreases extracellular GABA and increases extracellular glutamate and dopamine levels in the rat prefrontal cortex: an in vivo microdialysis study.
Journal: Brain research 20020906
Title: SR141716, a central cannabinoid (CB(1)) receptor antagonist, blocks the motivational and dopamine-releasing effects of nicotine in rats.
Journal: Behavioural pharmacology 20020901
Title: Effects of anandamide on embryo implantation in the mouse.
Journal: Life sciences 20020823
Title: Modulation of gastric emptying and gastrointestinal transit in rats through intestinal cannabinoid CB(1) receptors.
Journal: European journal of pharmacology 20020816
Title: Endocannabinoids are implicated in the infarct size-reducing effect conferred by heat stress preconditioning in isolated rat hearts.
Journal: Cardiovascular research 20020815
Title: Contrasting effects of WIN 55212-2 on motility of the rat bladder and uterus.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020815
Title: Memory impairment following combined exposure to delta(9)-tetrahydrocannabinol and ethanol in rats.
Journal: European journal of pharmacology 20020809
Title: Dose-dependent effects of Delta9-tetrahydrocannabinol on rates of local cerebral glucose utilization in rat.
Journal: Synapse (New York, N.Y.) 20020801
Title: Delta(9)-tetrahydrocannabinol-induced apoptosis in the thymus and spleen as a mechanism of immunosuppression in vitro and in vivo.
Journal: The Journal of pharmacology and experimental therapeutics 20020801
Title: The endogenous cannabinoid system controls extinction of aversive memories.
Journal: Nature 20020801
Title: Evidence for functional CB1 cannabinoid receptor expressed in the rat thyroid.
Journal: European journal of endocrinology 20020801
Title: The role of gap junctions in mediating endothelium-dependent responses to bradykinin in myometrial small arteries isolated from pregnant women.
Journal: British journal of pharmacology 20020801
Title: Role of the endocannabinoid system in MDMA intracerebral self-administration in rats.
Journal: British journal of pharmacology 20020801
Title: Involvement of the opioid system in the anxiolytic-like effects induced by Delta(9)-tetrahydrocannabinol.
Journal: Psychopharmacology 20020801
Title: Pharmacological activity of fatty acid amides is regulated, but not mediated, by fatty acid amide hydrolase in vivo.
Journal: The Journal of pharmacology and experimental therapeutics 20020701
Title: Characterization of the diarylether sulfonylester (-)-(R)-3-(2-hydroxymethylindanyl-4-oxy)phenyl-4,4,4-trifluoro-1-sulfonate (BAY 38-7271) as a potent cannabinoid receptor agonist with neuroprotective properties.
Journal: The Journal of pharmacology and experimental therapeutics 20020701
Title: Blockade of cannabinoid CB(1) receptor function protects against in vivo disseminating brain damage following NMDA-induced excitotoxicity.
Journal: Journal of neurochemistry 20020701
Title: Antinociceptive, behavioural and neuroendocrine effects of CP 55,940 in young rats.
Journal: Brain research. Developmental brain research 20020630
Title: Synthesis and structure-activity relationships of amide and hydrazide analogues of the cannabinoid CB(1) receptor antagonist N-(piperidinyl)- 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716).
Journal: Journal of medicinal chemistry 20020620
Title: Boosting effect of morphine on alcohol drinking is suppressed not only by naloxone but also by the cannabinoid CB1 receptor antagonist, SR 141716.
Journal: European journal of pharmacology 20020607
Title: Anandamide-induced vasorelaxation in rabbit aortic rings has two components: G protein dependent and independent.
Journal: American journal of physiology. Heart and circulatory physiology 20020601
Title: Evaluation of CB1 receptor knockout mice in the Morris water maze.
Journal: The Journal of pharmacology and experimental therapeutics 20020601
Title: The effect of cannabinoids on capsaicin-evoked calcitonin gene-related peptide (CGRP) release from the isolated paw skin of diabetic and non-diabetic rats.
Journal: Neuropharmacology 20020601
Title: Reversal of cannabinoids (delta9-THC) by the benzoflavone moiety from methanol extract of Passiflora incarnata Linneaus in mice: a possible therapy for cannabinoid addiction.
Journal: The Journal of pharmacy and pharmacology 20020601
Title: Cannabinoids inhibit excitatory inputs to neurons in the shell of the nucleus accumbens: an in vivo electrophysiological study.
Journal: The European journal of neuroscience 20020601
Title: Inhibition of GABAergic neurotransmission in the ventral tegmental area by cannabinoids.
Journal: The European journal of neuroscience 20020601
Title: The cannabinoid agonist DALN positively modulates L-type voltage-dependent calcium-channels in N18TG2 neuroblastoma cells.
Journal: Brain research. Molecular brain research 20020530
Title: Cannabinoid receptor antagonism and inverse agonism in response to SR141716A on cAMP production in human and rat brain.
Journal: European journal of pharmacology 20020517
Title: Blockade by the cannabinoid CB(1) receptor antagonist, SR 141716, of alcohol deprivation effect in alcohol-preferring rats.
Journal: European journal of pharmacology 20020517
Title: Delta(9)-tetrahydrocannabinol increases endogenous extracellular glutamate levels in primary cultures of rat cerebral cortex neurons: involvement of CB(1) receptors.
Journal: Journal of neuroscience research 20020515
Title: Presynaptic cannabinoid sensitivity is a major determinant of depolarization-induced retrograde suppression at hippocampal synapses.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020515
Title: Effect of opioid and cannabinoid receptor antagonism on orphanin FQ-induced hyperphagia in rats.
Journal: European journal of pharmacology 20020510
Title: Attenuation of nerve growth factor-induced visceral hyperalgesia via cannabinoid CB(1) and CB(2)-like receptors.
Journal: Pain 20020501
Title: [Increase of the heart arrhythmogenic resistance and decrease of the myocardial necrosis zone during activation of cannabinoid receptors].
Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20020501
Title: Cannabinoid CB(1) receptor blockade enhances the protective effect of melanocortins in hemorrhagic shock in the rat.
Journal: European journal of pharmacology 20020419
Title: Interaction between vanilloid and glutamate receptors in the central modulation of nociception.
Journal: European journal of pharmacology 20020329
Title: Arvanil-induced inhibition of spasticity and persistent pain: evidence for therapeutic sites of action different from the vanilloid VR1 receptor and cannabinoid CB(1)/CB(2) receptors.
Journal: European journal of pharmacology 20020329
Title: Molecular interaction of the antagonist N-(piperidin-1-yl)-5-(4-chlorophenyl)-1- (2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide with the CB1 cannabinoid receptor.
Journal: Journal of medicinal chemistry 20020328
Title: Role of CB1 and CB2 receptors in the inhibitory effects of cannabinoids on lipopolysaccharide-induced nitric oxide release in astrocyte cultures.
Journal: Journal of neuroscience research 20020315
Title: The cannabinoid CB1 receptor mediates retrograde signals for depolarization-induced suppression of inhibition in cerebellar Purkinje cells.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020301
Title: Effect of the cannabinoid receptor ligand, WIN 55,212-2, on superoxide anion and TNF-alpha production by human mononuclear cells.
Journal: International immunopharmacology 20020301
Title: SR 141716A prevents delta 9-tetrahydrocannabinol-induced spatial learning deficit in a Morris-type water maze in mice.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20020201
Title: Effect of the enzyme inhibitor, phenylmethylsulfonyl fluoride, on the IOP profiles of topical anandamides.
Journal: Investigative ophthalmology & visual science 20020201
Title: Motivational effects of cannabinoids are mediated by mu-opioid and kappa-opioid receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020201
Title: CB(1) receptor antagonist SR141716A inhibits Ca(2+)-induced relaxation in CB(1) receptor-deficient mice.
Journal: Hypertension (Dallas, Tex. : 1979) 20020201
Title: Evaluation of the reinforcing effects of the cannabinoid CB1 receptor antagonist, SR141716, in rhesus monkeys.
Journal: European journal of pharmacology 20020125
Title: The potent emetogenic effects of the endocannabinoid, 2-AG (2-arachidonoylglycerol) are blocked by delta(9)-tetrahydrocannabinol and other cannnabinoids.
Journal: The Journal of pharmacology and experimental therapeutics 20020101
Title: Endogenous cannabinoids: a new system involved in the homeostasis of arterial pressure in experimental cirrhosis in the rat.
Journal: Gastroenterology 20020101
Title: CB(1) receptor antagonist SR141716A increases capsaicin-evoked release of Substance P from the adult mouse spinal cord.
Journal: British journal of pharmacology 20020101
Title: Reversal of SR 141716A-induced head-twitch and ear-scratch responses in mice by delta 9-THC and other cannabinoids.
Journal: Pharmacology, biochemistry, and behavior 20020101
Title: Reversal of delta 9-THC hyperphagia by SR141716 and naloxone but not dexfenfluramine.
Journal: Pharmacology, biochemistry, and behavior 20020101
Title: Rimonabant. SR 141716, SR 141716a.
Journal: Drugs in R&D 20020101
Title: Cannabinoids attenuate depolarization-dependent Ca2+ influx in intermediate-size primary afferent neurons of adult rats.
Journal: Neuroscience 20020101
Title: Control by the endogenous cannabinoid system of ras oncogene-dependent tumor growth.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011201
Title: Inhibition of rat C6 glioma cell proliferation by endogenous and synthetic cannabinoids. Relative involvement of cannabinoid and vanilloid receptors.
Journal: The Journal of pharmacology and experimental therapeutics 20011201
Title: Selective cannabinoid CB1 receptor activation inhibits spinal nociceptive transmission in vivo.
Journal: Journal of neurophysiology 20011201
Title: Effects of the cannabinoid receptor antagonist SR 141716, alone and in combination with dexfenfluramine or naloxone, on food intake in rats.
Journal: Psychopharmacology 20011201
Title: Characteristics of learning and memory impairment induced by delta9-tetrahydrocannabinol in rats.
Journal: Japanese journal of pharmacology 20011201
Title: Activity of SR141716 on post-reinforcement pauses in operant responding for sucrose reward in rats.
Journal: Behavioural pharmacology 20011201
Title: Cannabinoid CB(1) receptor expression, activation and detection of endogenous ligand in trabecular meshwork and ciliary process tissues.
Journal: European journal of pharmacology 20011123
Title: Effects of the cannabinoid receptor agonist CP 55,940 and the cannabinoid receptor antagonist SR 141716 on intracranial self-stimulation in Lewis rats.
Journal: Life sciences 20011121
Title: Rapid tolerance to Delta(9)-tetrahydrocannabinol and cross-tolerance between ethanol and Delta(9)-tetrahydrocannabinol in mice.
Journal: European journal of pharmacology 20011116
Title: Exogenous anandamide protects rat brain against acute neuronal injury in vivo.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20011115
Title: The cannabinoid receptor antagonist SR 141716 prevents acquisition of drinking behavior in alcohol-preferring rats.
Journal: European journal of pharmacology 20011102
Title: Inhibitory effect of palmitoylethanolamide on gastrointestinal motility in mice.
Journal: British journal of pharmacology 20011101
Title: Anandamide-induced relaxation of sheep coronary arteries: the role of the vascular endothelium, arachidonic acid metabolites and potassium channels.
Journal: British journal of pharmacology 20011101
Title: Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats.
Journal: British journal of pharmacology 20011101
Title: Effects of cannabinoids on adrenaline release from adrenal medullary cells.
Journal: British journal of pharmacology 20011101
Title: The cannabinoid CB1 receptor antagonist SR 141716A reverses the antiemetic and motor depressant actions of WIN 55, 212-2.
Journal: European journal of pharmacology 20011026
Title: Cannabinoid receptor agonist WIN 55,212-2 inhibits rat cortical dialysate gamma-aminobutyric acid levels.
Journal: Journal of neuroscience research 20011015
Title: Interaction of anandamide with the M(1) and M(4) muscarinic acetylcholine receptors.
Journal: Brain research 20011005
Title: Cannabinoids inhibit nitric oxide production in bone marrow derived feline macrophages.
Journal: Veterinary immunology and immunopathology 20011001
Title: Cannabinoid CB1-receptor mediated regulation of gastrointestinal motility in mice in a model of intestinal inflammation.
Journal: British journal of pharmacology 20011001
Title: Cannabinoid activity curtails cocaine craving.
Journal: Nature medicine 20011001
Title: A cannabinoid mechanism in relapse to cocaine seeking.
Journal: Nature medicine 20011001
Title: Mechanisms of anandamide-induced vasorelaxation in rat isolated coronary arteries.
Journal: British journal of pharmacology 20011001
Title: Assessment of the role of CB1 receptors in cannabinoid anticonvulsant effects.
Journal: European journal of pharmacology 20010928
Title: Opioid and cannabinoid modulation of precipitated withdrawal in delta(9)-tetrahydrocannabinol and morphine-dependent mice.
Journal: The Journal of pharmacology and experimental therapeutics 20010901
Title: Cannabinoids attenuate capsaicin-evoked hyperalgesia through spinal and peripheral mechanisms.
Journal: Pain 20010901
Title: Neuroprotection by Delta9-tetrahydrocannabinol, the main active compound in marijuana, against ouabain-induced in vivo excitotoxicity.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010901
Title: Effects of chronic Delta(9)-tetrahydrocannabinol treatment on hippocampal extracellular acetylcholine concentration and alternation performance in the T-maze.
Journal: Neuropharmacology 20010901
Title: A possible role of lipoxygenase in the activation of vanilloid receptors by anandamide in the guinea-pig bronchus.
Journal: British journal of pharmacology 20010901
Title: Differential effects of anandamide on acetylcholine release in the guinea-pig ileum mediated via vanilloid and non-CB1 cannabinoid receptors.
Journal: British journal of pharmacology 20010901
Title: Cannabinoid effects on anxiety-related behaviours and hypothalamic neurotransmitters.
Journal: Pharmacology, biochemistry, and behavior 20010901
Title: Effects of CB1 cannabinoid receptor blockade on ethanol preference after chronic ethanol administration.
Journal: Alcoholism, clinical and experimental research 20010901
Title: SR141716, a CB1 receptor antagonist, decreases the sensitivity to the reinforcing effects of electrical brain stimulation in rats.
Journal: Psychopharmacology 20010901
Title: Activation of the CB1 cannabinoid receptor protects cultured mouse spinal neurons against excitotoxicity.
Journal: Neuroscience letters 20010831
Title: The cannabinoid CB(1) receptor antagonist SR141716A increases norepinephrine outflow in the rat anterior hypothalamus.
Journal: European journal of pharmacology 20010831
Title: Modulation of cytokine responses in Corynebacterium parvum-primed endotoxemic mice by centrally administered cannabinoid ligands.
Journal: European journal of pharmacology 20010803
Title: The cannabinoid receptor agonist WIN 55,212-2 regulates glutamate transmission in rat cerebral cortex: an in vivo and in vitro study.
Journal: Cerebral cortex (New York, N.Y. : 1991) 20010801
Title: Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor.
Journal: Cancer research 20010801
Title: (R)-methanandamide and Delta 9-THC as discriminative stimuli in rats: tests with the cannabinoid antagonist SR-141716 and the endogenous ligand anandamide.
Journal: Psychopharmacology 20010801
Title: Intravenous self-administration of the cannabinoid CB1 receptor agonist WIN 55,212-2 in rats.
Journal: Psychopharmacology 20010801
Title: Anandamide-induced sleep is blocked by SR141716A, a CB1 receptor antagonist and by U73122, a phospholipase C inhibitor.
Journal: Neuroreport 20010720
Title: CB1 receptor mediated analgesia from the Nucleus Reticularis Gigantocellularis pars alpha is activated in an animal model of neuropathic pain.
Journal: Brain research 20010720
Title: Functional interaction between opioid and cannabinoid receptors in drug self-administration.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010715
Title: Endogenously produced cannabinoids and liver cirrhosis.
Journal: Lancet (London, England) 20010707
Title: Hemodynamic effects of cannabinoids: coronary and cerebral vasodilation mediated by cannabinoid CB(1) receptors.
Journal: European journal of pharmacology 20010706
Title: Comparative characterization in the rat of the interaction between cannabinoids and opiates for their immunosuppressive and analgesic effects.
Journal: Journal of neuroimmunology 20010702
Title: Mechanisms of endocannabinoid inactivation: biochemistry and pharmacology.
Journal: The Journal of pharmacology and experimental therapeutics 20010701
Title: Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis.
Journal: Nature medicine 20010701
Title: Identification of two distinct vasodilator pathways activated by ATP in the mesenteric bed of the rat.
Journal: British journal of pharmacology 20010701
Title: Effects of cannabinoids on prefrontal neuronal responses to ventral tegmental area stimulation.
Journal: The European journal of neuroscience 20010701
Title: Delta 9-tetrahydrocannabinol-induced MAPK/ERK and Elk-1 activation in vivo depends on dopaminergic transmission.
Journal: The European journal of neuroscience 20010701
Title: The central cannabinoid receptor inactivation suppresses endocrine reproductive functions.
Journal: Biochemical and biophysical research communications 20010608
Title: The synthetic cannabinoid WIN55,212-2 attenuates hyperalgesia and allodynia in a rat model of neuropathic pain.
Journal: British journal of pharmacology 20010601
Title: Cannabinoid receptor agonist and antagonist effects on motor function in normal and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP)-treated non-human primates.
Journal: Psychopharmacology 20010601
Title: Inhibition of peristaltic activity by cannabinoids in the isolated distal colon of mouse.
Journal: Life sciences 20010525
Title: Cannabinoids inhibit the formation of new synapses between hippocampal neurons in culture.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010515
Title: Cannabinoid receptor agonist-stimulated [35S]guanosine triphosphate gammaS binding in the brain of C57BL/6 and DBA/2 mice.
Journal: Journal of neuroscience research 20010515
Title: Delta9-tetrahydrocannabinol enhances cortical and hippocampal acetylcholine release in vivo: a microdialysis study.
Journal: European journal of pharmacology 20010511
Title: Critical role of the endogenous cannabinoid system in mouse pup suckling and growth.
Journal: European journal of pharmacology 20010511
Title: Cannabinoid CB(1) receptor agonists produce cerebellar dysfunction in mice.
Journal: The Journal of pharmacology and experimental therapeutics 20010501
Title: Presynaptic mechanisms underlying cannabinoid inhibition of excitatory synaptic transmission in rat striatal neurons.
Journal: The Journal of physiology 20010501
Title: The role of central and peripheral Cannabinoid1 receptors in the antihyperalgesic activity of cannabinoids in a model of neuropathic pain.
Journal: Pain 20010501
Title: The activity of anandamide at vanilloid VR1 receptors requires facilitated transport across the cell membrane and is limited by intracellular metabolism.
Journal: The Journal of biological chemistry 20010420
Title: Cannabinoid inhibition of capsaicin-sensitive sensory neurotransmission in the rat mesenteric arterial bed.
Journal: European journal of pharmacology 20010420
Title: Leptin-regulated endocannabinoids are involved in maintaining food intake.
Journal: Nature 20010412
Title: Effect of vanilloid drugs on gastrointestinal transit in mice.
Journal: British journal of pharmacology 20010401
Title: Blockade of effects of smoked marijuana by the CB1-selective cannabinoid receptor antagonist SR141716.
Journal: Archives of general psychiatry 20010401
Title: Cannabinoid antagonists: a treatment in search of an illness.
Journal: Archives of general psychiatry 20010401
Title: Reduction of opioid dependence by the CB(1) antagonist SR141716A in mice: evaluation of the interest in pharmacotherapy of opioid addiction.
Journal: British journal of pharmacology 20010401
Title: Pharmacological properties of cannabinoid receptors in the avian brain: similarity of rat and chicken cannabinoid1 receptor recognition sites and expression of cannabinoid2 receptor-like immunoreactivity in the embryonic chick brain.
Journal: Pharmacology & toxicology 20010401
Title: Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses.
Journal: Nature 20010329
Title: Spontaneous and precipitated withdrawal with a synthetic cannabinoid, WIN 55212-2.
Journal: European journal of pharmacology 20010323
Title: Inhibitory effects of SR141716A on G-protein activation in rat brain.
Journal: European journal of pharmacology 20010302
Title: Metabotropic and NMDA glutamate receptors participate in the cannabinoid-induced antinociception.
Journal: Neuropharmacology 20010301
Title: Novel pyrazole cannabinoids: insights into CB(1) receptor recognition and activation.
Journal: The Journal of pharmacology and experimental therapeutics 20010301
Title: Cannabinoid inhibition of the capsaicin-induced calcium response in rat dorsal root ganglion neurones.
Journal: British journal of pharmacology 20010301
Title: Cannabinoidergic and opioidergic inhibition of spinal reflexes in the decerebrated, spinalized rabbit.
Journal: Neuropharmacology 20010301
Title: Enhanced acetylcholine release in the hippocampus of cannabinoid CB(1) receptor-deficient mice.
Journal: British journal of pharmacology 20010301
Title: Pharmacological analysis of cannabinoid receptor activity in the rat vas deferens.
Journal: British journal of pharmacology 20010301
Title: 2-Arachidonoylglycerol, a candidate of endothelium-derived hyperpolarizing factor.
Journal: European journal of pharmacology 20010301
Title: Endogenous cannabinoid anandamide increases heart resistance to arrhythmogenic effects of epinephrine: role of CB(1) and CB(2) receptors.
Journal: Bulletin of experimental biology and medicine 20010301
Title: Cannabinoids and pain.
Journal: Current opinion in investigational drugs (London, England : 2000) 20010301
Title: Intracerebral self-administration of the cannabinoid receptor agonist CP 55,940 in the rat: interaction with the opioid system.
Journal: European journal of pharmacology 20010216
Title: Delta(9)-tetrahydrocannabinol and synthetic cannabinoids prevent emesis produced by the cannabinoid CB(1) receptor antagonist/inverse agonist SR 141716A.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010201
Title: Endocannabinoids control spasticity in a multiple sclerosis model.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010201
Title: Structure-activity relationship for the endogenous cannabinoid, anandamide, and certain of its analogues at vanilloid receptors in transfected cells and vas deferens.
Journal: British journal of pharmacology 20010201
Title: Regional differences in anandamide- and methanandamide-induced membrane potential changes in rat mesenteric arteries.
Journal: The Journal of pharmacology and experimental therapeutics 20010201
Title: delta(9)-Tetrahydrocannabinol increases nerve growth factor production by prostate PC-3 cells. Involvement of CB1 cannabinoid receptor and Raf-1.
Journal: European journal of biochemistry 20010201
Title: Human platelets bind and degrade 2-arachidonoylglycerol, which activates these cells through a cannabinoid receptor.
Journal: European journal of biochemistry 20010201
Title: Involvement of cannabinoids in the cardioprotection induced by lipopolysaccharide.
Journal: British journal of pharmacology 20010201
Title: Cannabinoid CB1-mediated inhibition of stress-induced gastric ulcers in rats.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010201
Title: Effects of SR141716A on ethanol and sucrose self-administration.
Journal: Alcoholism, clinical and experimental research 20010201
Title: The endocannabinoid anandamide is a direct and selective blocker of the background K(+) channel TASK-1.
Journal: The EMBO journal 20010115
Title: Systemic and portal hemodynamic effects of anandamide.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20010101
Title: CB1 cannabinoid receptor inhibits synaptic release of glutamate in rat dorsolateral striatum.
Journal: Journal of neurophysiology 20010101
Title: Cannabinoid CB1 receptor-mediated inhibition of acetylcholine release in the brain of NMRI, CD-1 and C57BL/6J mice.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010101
Title: Synergistic efects of opioid and cannabinoid antagonists on food intake.
Journal: Psychopharmacology 20010101
Title: Precipitated cannabinoid withdrawal is reversed by Delta(9)-tetrahydrocannabinol or clonidine.
Journal: Pharmacology, biochemistry, and behavior 20010101
Title: Delta-9-tetrahydrocannabinol differentially suppresses cisplatin-induced emesis and indices of motor function via cannabinoid CB(1) receptors in the least shrew.
Journal: Pharmacology, biochemistry, and behavior 20010101
Title: Cannabinoid-induced motor incoordination through the cerebellar CB(1) receptor in mice.
Journal: Pharmacology, biochemistry, and behavior 20010101
Title: Conditioned place preference induced by the cannabinoid agonist CP 55,940: interaction with the opioid system.
Journal: Neuroscience 20010101
Title: [Antiarrhythmic properties of a cannabinoid (CB) receptor agonist].
Journal: Eksperimental'naia i klinicheskaia farmakologiia 20010101
Title: Novel cannabinoid-sensitive receptor mediates inhibition of glutamatergic synaptic transmission in the hippocampus.
Journal: Neuroscience 20010101
Title: Cannabinoid-mediated inhibition of inducible nitric oxide production by rat microglial cells: evidence for CB1 receptor participation.
Journal: Advances in experimental medicine and biology 20010101
Title: Involvement of central and peripheral cannabinoid receptors in the regulation of heart resistance to arrhythmogenic effects of epinephrine.
Journal: Bulletin of experimental biology and medicine 20001101
Title: CB1 cannabinoid receptor-mediated cell migration.
Journal: The Journal of pharmacology and experimental therapeutics 20000701
Title: The anandamide transport inhibitor AM404 activates vanilloid receptors.
Journal: European journal of pharmacology 20000512
Title: Cannabinoid CB(1) receptors colocalize with tyrosine hydroxylase in cultured fetal mesencephalic neurons and their activation increases the levels of this enzyme.
Journal: Brain research 20000227
Title: Evidence that 2-arachidonoylglycerol but not N-palmitoylethanolamine or anandamide is the physiological ligand for the cannabinoid CB2 receptor. Comparison of the agonistic activities of various cannabinoid receptor ligands in HL-60 cells.
Journal: The Journal of biological chemistry 20000107
Title: HU-308: a specific agonist for CB(2), a peripheral cannabinoid receptor.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19991207
Title: Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19991123
Title: The role of cannabinoid receptors in intestinal motility, defaecation and diarrhoea in rats.
Journal: European journal of pharmacology 19991112
Title: CB1 cannabinoid receptor agonist WIN 55,212-2 decreases intravenous cocaine self-administration in rats.
Journal: Behavioural brain research 19991001
Title: Dual intracellular signaling pathways mediated by the human cannabinoid CB1 receptor.
Journal: European journal of pharmacology 19990625
Title: The central cannabinoid receptor (CB1) mediates inhibition of nitric oxide production by rat microglial cells.
Journal: The Journal of pharmacology and experimental therapeutics 19990301
Title: Structure-activity relationships of pyrazole derivatives as cannabinoid receptor antagonists.
Journal: Journal of medicinal chemistry 19990225
Title: Effects of cannabinoids on prolactin and gonadotrophin secretion: involvement of changes in hypothalamic gamma-aminobutyric acid (GABA) inputs.
Journal: Biochemical pharmacology 19981115
Title: Delta9-tetrahydrocannabinol increases sequence-specific AP-1 DNA-binding activity and Fos-related antigens in the rat brain.
Journal: The European journal of neuroscience 19980501
Title: Comparative receptor binding analyses of cannabinoid agonists and antagonists.
Journal: The Journal of pharmacology and experimental therapeutics 19980401
Title: LY320135, a novel cannabinoid CB1 receptor antagonist, unmasks coupling of the CB1 receptor to stimulation of cAMP accumulation.
Journal: The Journal of pharmacology and experimental therapeutics 19980101
Title: Regulation of delta opioid receptors by delta9-tetrahydrocannabinol in NG108-15 hybrid cells.
Journal: Life sciences 19980101
Title: The cannabinoid receptor agonist WIN 55,212-2 reduces D2, but not D1, dopamine receptor-mediated alleviation of akinesia in the reserpine-treated rat model of Parkinson's disease.
Journal: Experimental neurology 19971101
Title: Regional differences in cannabinoid receptor/G-protein coupling in rat brain.
Journal: The Journal of pharmacology and experimental therapeutics 19970901
Title: Cannabinoid-induced hypotension and bradycardia in rats mediated by CB1-like cannabinoid receptors.
Journal: The Journal of pharmacology and experimental therapeutics 19970601
Title: delta 9-Tetrahydrocannabinol increases activity of tyrosine hydroxylase in cultured fetal mesencephalic neurons.
Journal: Journal of molecular neuroscience : MN 19970401
Title: Characterization of CB1 receptors on rat neuronal cell cultures: binding and functional studies using the selective receptor antagonist SR 141716A.
Journal: Journal of neurochemistry 19970101
Title: Characterisation of the rat cerebella CB1 receptor using SR141716A, a central cannabinoid receptor antagonist.
Journal: Neuroscience letters 19961213
Title: Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands.
Journal: The Journal of pharmacology and experimental therapeutics 19960901
Title: Structural features of the central cannabinoid CB1 receptor involved in the binding of the specific CB1 antagonist SR 141716A.
Journal: The Journal of biological chemistry 19960322
Title: Biochemical and pharmacological characterization of cannabinoid binding sites using [3H]SR141716A.
Journal: Neuroreport 19960227
Title: Characterization and distribution of binding sites for [3H]-SR 141716A, a selective brain (CB1) cannabinoid receptor antagonist, in rodent brain.
Journal: Life sciences 19960101
Title: Anandamide, an endogenous cannabinoid, inhibits Shaker-related voltage-gated K+ channels.
Journal: Neuropharmacology 19960101
Title: Activation of mitogen-activated protein kinases by stimulation of the central cannabinoid receptor CB1.
Journal: The Biochemical journal 19951201
Title: Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors.
Journal: Molecular pharmacology 19950901
Title: SR141716A, a potent and selective antagonist of the brain cannabinoid receptor.
Journal: FEBS letters 19940822
Title: Fasting induces CART down-regulation in the zebrafish nervous system in a cannabinoid receptor 1-dependent manner.
Journal: Molecular endocrinology (Baltimore, Md.)
Title: Seely KA, Brents LK, Franks LN, Rajasekaran M, Zimmerman SM, Fantegrossi WE, Prather PL.AM-251 and rimonabant act as direct antagonists at mu-opioid receptors: Implications for opioid/cannabinoid interaction studies.Neuropharmacology. 2012 Oct;63(5):905-15.
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