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16830-15-2,MFCD06642601
Catalog No.:AA001XY0

16830-15-2 | Asiaticoside

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5mg
≥95%
in stock  
$53.00   $37.00
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10mg
≥95%
in stock  
$98.00   $68.00
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25mg
98% by HPLC
in stock  
$174.00   $122.00
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50mg
98% by HPLC
in stock  
$250.00   $175.00
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100mg
98% by HPLC
in stock  
$386.00   $270.00
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500mg
98% by HPLC
in stock  
$1,103.00   $772.00
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1000mg
98% by HPLC
in stock  
$1,726.00   $1,208.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA001XY0
Chemical Name:
Asiaticoside
CAS Number:
16830-15-2
Molecular Formula:
C48H78O19
Molecular Weight:
959.1215
MDL Number:
MFCD06642601
SMILES:
OCC1OC(OCC2OC(OC(=O)C34CCC(C(C4C4=CCC5C(C4(CC3)C)(C)CCC3C5(C)CC(C(C3(C)CO)O)O)C)C)C(C(C2O)O)O)C(C(C1OC1OC(C)C(C(C1O)O)O)O)O
Properties
Computed Properties
 
Complexity:
1820  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
27  
Heavy Atom Count:
67  
Hydrogen Bond Acceptor Count:
19  
Hydrogen Bond Donor Count:
12  
Rotatable Bond Count:
10  
XLogP3:
0.1  

Literature

Title: Isolation and identification of an anti-hepatitis B virus compound from Hydrocotyle sibthorpioides Lam.

Journal: Journal of ethnopharmacology 20131125

Title: Improved in vitro and in vivo collagen biosynthesis by asiaticoside-loaded ultradeformable vesicles.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20120820

Title: Growth and asiaticoside production in multiple shoot cultures of a medicinal herb, Centella asiatica (L.) Urban, under the influence of nutrient manipulations.

Journal: Journal of natural medicines 20120401

Title: Asiaticoside: attenuation of neurotoxicity induced by MPTP in a rat model of Parkinsonism via maintaining redox balance and up-regulating the ratio of Bcl-2/Bax.

Journal: Pharmacology, biochemistry, and behavior 20120101

Title: Effect of asiaticoside on 99mTc-tetrofosmin and 99mTc-sestamibi uptake in MCF-7 cells.

Journal: Journal of nuclear medicine technology 20111201

Title: Asiaticoside suppresses collagen expression and TGF-β/Smad signaling through inducing Smad7 and inhibiting TGF-βRI and TGF-βRII in keloid fibroblasts.

Journal: Archives of dermatological research 20111001

Title: Bioassay-guided isolation of anti-inflammatory, antinociceptive and wound healer glycosides from the flowers of Verbascum mucronatum Lam.

Journal: Journal of ethnopharmacology 20110714

Title: In vitro inhibitory effects of asiaticoside and madecassoside on human cytochrome P450.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20110601

Title: Investigating wound healing, tyrosinase inhibitory and antioxidant activities of the ethanol extracts of Salvia cryptantha and Salvia cyanescens using in vivo and in vitro experimental models.

Journal: Journal of ethnopharmacology 20110426

Title: Wound healing acceleration effect of endemic Ononis species growing in Turkey.

Journal: Journal of ethnopharmacology 20110426

Title: Interesting linkage between wound healing and hepatoprotective activities.

Journal: Chemico-biological interactions 20110425

Title: [The cellular and molecular mechanism of inhibitory effect of asiaticoside on capsular contracture following breast augmentation].

Journal: Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery 20110101

Title: In vitro biological evaluation of electrospun cellulose acetate fiber mats containing asiaticoside or curcumin.

Journal: Journal of biomedical materials research. Part A 20100915

Title: Protective effects of Asiaticoside on acute liver injury induced by lipopolysaccharide/D-galactosamine in mice.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20100801

Title: In vitro modulatory effects on three major human cytochrome P450 enzymes by multiple active constituents and extracts of Centella asiatica.

Journal: Journal of ethnopharmacology 20100720

Title: Wound healing potential of Sambucus ebulus L. leaves and isolation of an active component, quercetin 3-O-glucoside.

Journal: Journal of ethnopharmacology 20100504

Title: Upregulation of phytosterol and triterpene biosynthesis in Centella asiatica hairy roots overexpressed ginseng farnesyl diphosphate synthase.

Journal: Plant cell reports 20100401

Title: Contact dermatitis due to Centella asiatica.

Journal: Contact dermatitis 20100101

Title: Exploring the wound healing activity of Arnebia densiflora (Nordm.) Ledeb. by in vivo models.

Journal: Journal of ethnopharmacology 20090706

Title: Enrichment and purification of madecassoside and asiaticoside from Centella asiatica extracts with macroporous resins.

Journal: Journal of chromatography. A 20080606

Title: Antidepressant-like effect of asiaticoside in mice.

Journal: Pharmacology, biochemistry, and behavior 20080501

Title: [Preparation of asiaticoside and madecassoside from the extract of Centella asiatica (L.) Urb using preparative high performance liquid chromatography].

Journal: Se pu = Chinese journal of chromatography 20080501

Title: Inhibition of LPS-induced NO and PGE2 production by asiatic acid via NF-kappa B inactivation in RAW 264.7 macrophages: possible involvement of the IKK and MAPK pathways.

Journal: International immunopharmacology 20080301

Title: Simultaneous quantitation of three major triterpenoid glycosides in Centella asiatica extracts by high performance liquid chromatography with evaporative light scattering detection.

Journal: Biomedical chromatography : BMC 20080201

Title: Enhanced production of asiaticoside from hairy root cultures of Centella asiatica (L.) Urban elicited by methyl jasmonate.

Journal: Plant cell reports 20071101

Title: [Inhibitiory action of asiaiticoside on collagen-induced arthritis in mice].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20070701

Title: Evaluation of anxiolytic properties of Gotukola--(Centella asiatica) extracts and asiaticoside in rat behavioral models.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20061101

Title: Anxiolytic-like effect of asiaticoside in mice.

Journal: Pharmacology, biochemistry, and behavior 20061001

Title: Cytotoxic cycloartane triterpene saponins from Actaea asiatica.

Journal: Journal of natural products 20061001

Title: Identification of triterpenoid compounds of Centella asiatica by thin-layer chromatography and mass spectrometry.

Journal: Biomedical chromatography : BMC 20060201

Title: Cloning of a cDNA probably encoding oxidosqualene cyclase associated with asiaticoside biosynthesis from Centella asiatica (L.) Urban.

Journal: Plant cell reports 20050701

Title: Inhibitory effects of Centella asiatica water extract and asiaticoside on inducible nitric oxide synthase during gastric ulcer healing in rats.

Journal: Planta medica 20041201

Title: Stimulation of asiaticoside accumulation in the whole plant cultures of Centella asiatica (L.) urban by elicitors.

Journal: Plant cell reports 20041101

Title: The healing effects of Centella extract and asiaticoside on acetic acid induced gastric ulcers in rats.

Journal: Life sciences 20040319

Title: Contact allergy to various ingredients of topical medicaments.

Journal: Contact dermatitis 20030701

Title: In vitro keratinocyte antiproliferant effect of Centella asiatica extract and triterpenoid saponins.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20010501

Title: Tang B, et al. Asiaticoside suppresses collagen expression and TGF-β/Smad signaling through inducing Smad7 and inhibiting TGF-βRI and TGF-βRII in keloid fibroblasts. h Dermatol Res. 2011 Oct;303(8):563-72.

Title: Wang X, et al. Effect of asiaticoside on endothelial cells in hypoxia‑induced pulmonary hypertension. Mol Med Rep. 2018 Feb;17(2):2893-2900.

Title: Zhang Z, et al. Asiaticoside ameliorates β-amyloid-induced learning and memory deficits in rats by inhibiting mitochondrial apoptosis and reducing inflammatory factors. Exp Ther Med. 2017 Feb;13(2):413-420.

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