[1]Tsunoda,Takashi;Tanaka,Akihiro;Mase,Toshiyasu;Sakamoto,Shuichi[Heterocycles,2004,vol.63,#5,p.1113-1122]
[1]Tsunoda,Takashi;Tanaka,Akihiro;Mase,Toshiyasu;Sakamoto,Shuichi[Heterocycles,2004,vol.63,#5,p.1113-1122]
[1]Tsunoda,Takashi;Tanaka,Akihiro;Mase,Toshiyasu;Sakamoto,Shuichi[Heterocycles,2004,vol.63,#5,p.1113-1122]
[1]Heterocycles,2004,vol.63,p.1113-1122
[2]OrganicProcessResearchandDevelopment,2005,vol.9,p.593-598
[1]Tsunoda,Takashi;Tanaka,Akihiro;Mase,Toshiyasu;Sakamoto,Shuichi[Heterocycles,2004,vol.63,#5,p.1113-1122]
[2]Tsunoda,Takashi;Yamazaki,Atsuki;Iwamoto,Hidenori;Sakamoto,Shuichi[OrganicProcessResearchandDevelopment,2003,vol.7,#6,p.883-887]
[3]Tsunoda,Takashi;Yamazaki,Atsuki;Iwamoto,Hidenori;Sakamoto,Shuichi[OrganicProcessResearchandDevelopment,2003,vol.7,#6,p.883-887]
Title: Hyponatremia, heart failure, and the role of tolvaptan.
Journal: Postgraduate medicine 20120301
Title: The roles of V1a vasopressin receptors in blood pressure homeostasis: a review of studies on V1a receptor knockout mice.
Journal: Clinical and experimental nephrology 20120201
Title: Hyponatremia and the use of vasopressin receptor antagonists in critically ill patients.
Journal: Journal of intensive care medicine 20120101
Title: Novel treatment targets for cerebral edema.
Journal: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20120101
Title: [Hyponatremic syndrome].
Journal: La Clinica terapeutica 20120101
Title: [Hyponatremic hypervolemia in heart failure--the hot spot for vasopressin receptor antagonists?].
Journal: Wiadomosci lekarskie (Warsaw, Poland : 1960) 20120101
Title: Conivaptan therapy in an infant with severe hyponatremia and congestive heart failure.
Journal: Texas Heart Institute journal 20120101
Title: Renal effects of conivaptan, furosemide, and the combination in patients with chronic heart failure.
Journal: Journal of cardiac failure 20111201
Title: Controlling the flood gates: vaptans, furosemide and the quest for a renal protective diuresis.
Journal: Journal of cardiac failure 20111201
Title: Targeting hyponatremia and hemodynamics in acute decompensated heart failure: is there a role for vasopressin antagonists?
Journal: Current heart failure reports 20110901
Title: Vaptans are not the mainstay of treatment in hyponatremia: perhaps not yet.
Journal: Kidney international 20110901
Title: Use of intravenous conivaptan in neurosurgical patients with hyponatremia from syndrome of inappropriate antidiuretic hormone secretion.
Journal: Neurosurgery 20110801
Title: The therapeutic use of vaptans for the treatment of dilutional hyponatremia.
Journal: Journal of pharmacy practice 20110801
Title: Open-label randomized trial of the safety and efficacy of a single dose conivaptan to raise serum sodium in patients with traumatic brain injury.
Journal: Neurocritical care 20110601
Title: Efficacy and safety of 30-minute infusions of conivaptan in euvolemic and hypervolemic hyponatremia.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110501
Title: Arginine vasopressin (AVP) and treatment with arginine vasopressin receptor antagonists (vaptans) in congestive heart failure, liver cirrhosis and syndrome of inappropriate antidiuretic hormone secretion (SIADH).
Journal: European journal of clinical pharmacology 20110401
Title: Effect of loading dose and formulation on safety and efficacy of conivaptan in treatment of euvolemic and hypervolemic hyponatremia.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110401
Title: Hyponatremia: vasopressin antagonists in hyponatremia: more data needed.
Journal: Nature reviews. Nephrology 20110301
Title: A bolus of conivaptan lowers intracranial pressure in a patient with hyponatremia after traumatic brain injury.
Journal: Neurocritical care 20110201
Title: Differentiation of arginine vasopressin antagonistic effects by selective V2 versus dual V2/V1a receptor blockade in a preclinical heart failure model.
Journal: American journal of therapeutics 20110101
Title: The syndrome of inappropriate antidiuresis: pathophysiology, clinical management and new therapeutic options.
Journal: Nephron. Clinical practice 20110101
Title: Hyponatremia in acute decompensated heart failure: mechanisms, prognosis, and treatment options.
Journal: Clinical cardiology 20101101
Title: Extreme correction of hyponatremia in a patient treated with intravenous conivaptan.
Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20101001
Title: Arginine vasopressin receptor antagonists (vaptans): pharmacological tools and potential therapeutic agents.
Journal: Drug discovery today 20101001
Title: Use of Conivaptan (Vaprisol) for hyponatremic neuro-ICU patients.
Journal: Neurocritical care 20100801
Title: Synthesis and evaluation of azabicyclo[3.2.1]octane derivatives as potent mixed vasopressin antagonists.
Journal: Bioorganic & medicinal chemistry letters 20100615
Title: Use of conivaptan for the treatment of symptomatic hyponatremia in a patient with acute decompensated heart failure.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100615
Title: Sodium, potassium and glucose management in organ transplantation.
Journal: Current opinion in organ transplantation 20100601
Title: Intravenous conivaptan for the treatment of hyponatraemia caused by the syndrome of inappropriate secretion of antidiuretic hormone in hospitalized patients: a single-centre experience.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100501
Title: The vaptans: just landed. But how was the trip?
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100501
Title: The critical link of hypervolemia and hyponatremia in heart failure and the potential role of arginine vasopressin antagonists.
Journal: Journal of cardiac failure 20100501
Title: [Hyponatremia in heart failure: physiopathology and pharmacological approach].
Journal: Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20100501
Title: [Vasopressin receptor antagonists: the vaptans].
Journal: Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20100501
Title: Vasopressin antagonists: Pharmacotherapy for the treatment of heart failure.
Journal: The Annals of pharmacotherapy 20100401
Title: Vasopressin receptor antagonist use in a neurologic rehabilitation center.
Journal: The journal of spinal cord medicine 20100201
Title: Hyponatremia: evaluation and management.
Journal: Hospital practice (1995) 20100201
Title: Potential of endothelin-1 and vasopressin antagonists for the treatment of congestive heart failure.
Journal: Heart failure reviews 20100101
Title: Novel agents for the treatment of hyponatremia: a review of conivaptan and tolvaptan.
Journal: Cardiology in review 20100101
Title: Tolvaptan (Samsca) for hyponatremia.
Journal: The Medical letter on drugs and therapeutics 20091130
Title: [Vasopressin receptor antagonists and heart failure].
Journal: Therapeutische Umschau. Revue therapeutique 20091101
Title: Conivaptan increases serum sodium in hyponatremic patients with end-stage liver disease.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20091001
Title: Conivaptan: promise of treatment in heart failure.
Journal: Expert opinion on pharmacotherapy 20090901
Title: Successful treatment of ifosfamide-induced hyponatremia with AVP receptor antagonist without interruption of hydration for prevention of hemorrhagic cystitis.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20090701
Title: Pharmacokinetics of conivaptan hydrochloride, a vasopressin V(1A)/V(2)-receptor antagonist, in patients with euvolemic or hypervolemic hyponatremia and with or without congestive heart failure from a prospective, 4-day open-label study.
Journal: Clinical therapeutics 20090701
Title: Pharmacology of vasopressin antagonists.
Journal: Heart failure reviews 20090601
Title: AVP receptor antagonists in patients with CHF.
Journal: Heart failure reviews 20090601
Title: Hyponatremia: case vignettes.
Journal: Seminars in nephrology 20090501
Title: Conivaptan for hyponatremia in the neurocritical care unit.
Journal: Neurocritical care 20090101
Title: Efficacy and safety of oral conivaptan, a vasopressin-receptor antagonist, evaluated in a randomized, controlled trial in patients with euvolemic or hypervolemic hyponatremia.
Journal: The American journal of the medical sciences 20090101
Title: Conivaptan bolus dosing for the correction of hyponatremia in the neurointensive care unit.
Journal: Neurocritical care 20090101
Title: New topics in vasopressin receptors and approach to novel drugs: research and development of conivaptan hydrochloride (YM087), a drug for the treatment of hyponatremia.
Journal: Journal of pharmacological sciences 20090101
Title: Role of vasopressin and vasopressin receptor antagonists in type I cardiorenal syndrome.
Journal: Blood purification 20090101
Title: Hyponatremia in heart failure.
Journal: Journal of intensive care medicine 20090101
Title: Efficacy and safety of the vasopressin V1A/V2-receptor antagonist conivaptan in acute decompensated heart failure: a dose-ranging pilot study.
Journal: Journal of cardiac failure 20081001
Title: Vasopressin antagonists for the treatment of acute decompensated heart failure: when, for whom, for how long, and on what standard therapy?
Journal: Journal of cardiac failure 20081001
Title: Use of conivaptan to allow aggressive hydration to prevent tumor lysis syndrome in a pediatric patient with large-cell lymphoma and SIADH.
Journal: Pediatric nephrology (Berlin, Germany) 20080801
Title: [Etiology, diagnostics and therapy of hyponatremias].
Journal: Orvosi hetilap 20080720
Title: Assessment of the efficacy and safety of intravenous conivaptan in patients with euvolaemic hyponatraemia: subgroup analysis of a randomized, controlled study.
Journal: Clinical endocrinology 20080701
Title: Conivaptan: potential therapeutic implications in heart failure.
Journal: Recent patents on cardiovascular drug discovery 20080601
Title: Vasopressin and vasopressin antagonists in heart failure and hyponatremia.
Journal: Current heart failure reports 20080601
Title: Non-peptide arginine-vasopressin antagonists: the vaptans.
Journal: Lancet (London, England) 20080510
Title: Vasopressin-receptor antagonists in heart failure.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080501
Title: The management of ascites and hyponatremia in cirrhosis.
Journal: Seminars in liver disease 20080201
Title: Hyponatremia in psychiatric patients: update on evaluation and management.
Journal: Harvard review of psychiatry 20080101
Title: Observations regarding the use of the aquaretic agent conivaptan for treatment of hyponatremia.
Journal: International urology and nephrology 20080101
Title: Peptide and non-peptide agonists and antagonists for the vasopressin and oxytocin V1a, V1b, V2 and OT receptors: research tools and potential therapeutic agents.
Journal: Progress in brain research 20080101
Title: Intravenous conivaptan.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20080101
Title: Hyponatremia and vasopressin antagonism in congestive heart failure.
Journal: Clinical cardiology 20071101
Title: Current issues for nurse practitioners: Hyponatremia.
Journal: Journal of the American Academy of Nurse Practitioners 20071101
Title: Hyponatremia: clinical diagnosis and management.
Journal: The American journal of medicine 20070801
Title: [Vasopressin antagonists in treatment of hyponatremia].
Journal: Polskie Archiwum Medycyny Wewnetrznej 20070801
Title: Conivaptan: new treatment for hyponatremia.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070701
Title: Clinical practice. The syndrome of inappropriate antidiuresis.
Journal: The New England journal of medicine 20070517
Title: New drugs 07, part I.
Journal: Nursing 20070201
Title: Management of hyponatremia and clinical use of vasopressin antagonists.
Journal: The American journal of the medical sciences 20070201
Title: Recognition and treatment of hyponatremia in acutely ill hospitalized patients.
Journal: Clinical therapeutics 20070201
Title: [Arginine vasopressin antagonism--new treatment option in chronic heart failure].
Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20070118
Title: A novel vasopressin dual V1A/V2 receptor antagonist, conivaptan hydrochloride, improves hyponatremia in rats with syndrome of inappropriate secretion of antidiuretic hormone (SIADH).
Journal: Biological & pharmaceutical bulletin 20070101
Title: Therapeutic potential of vasopressin receptor antagonists.
Journal: Drugs 20070101
Title: Intravenous conivaptan: effects on the QTc interval and other electrocardiographic parameters in healthy volunteers.
Journal: Advances in therapy 20070101
Title: Assessment of the efficacy and safety of intravenous conivaptan in euvolemic and hypervolemic hyponatremia.
Journal: American journal of nephrology 20070101
Title: Conivaptan: a dual vasopressin receptor v1a/v2 antagonist [corrected].
Journal: Cardiovascular drug reviews 20070101
Title: Vasopressin antagonists--progress and promise.
Journal: The New England journal of medicine 20061116
Title: Excipient hydrolysis and ester formation increase pH in a parenteral solution over aging.
Journal: International journal of pharmaceutics 20061115
Title: Molecule of the Month: Conivaptan hydrochloride.
Journal: Drug news & perspectives 20061101
Title: Hyponatremia in cirrhosis: clinical features and management.
Journal: Gastroenterologie clinique et biologique 20061001
Title: AVP receptor antagonists as aquaretics: review and assessment of clinical data.
Journal: Cleveland Clinic journal of medicine 20060901
Title: Vasopressin antagonists.
Journal: Cellular and molecular life sciences : CMLS 20060801
Title: Vasopressin antagonists as aquaretic agents for the treatment of hyponatremia.
Journal: The American journal of medicine 20060701
Title: Conivaptan (Vaprisol) for hyponatremia.
Journal: The Medical letter on drugs and therapeutics 20060619
Title: Cardiac function and heart failure.
Journal: Journal of the American College of Cardiology 20060606
Title: Efficacy and safety of oral conivaptan: a V1A/V2 vasopressin receptor antagonist, assessed in a randomized, placebo-controlled trial in patients with euvolemic or hypervolemic hyponatremia.
Journal: The Journal of clinical endocrinology and metabolism 20060601
Title: Vasopressin receptor antagonists.
Journal: Kidney international 20060601
Title: Conivaptan: a selective vasopressin antagonist.
Journal: Drugs of today (Barcelona, Spain : 1998) 20060601
Title: Vasopressin receptor antagonists in heart failure.
Journal: Recent patents on cardiovascular drug discovery 20060601
Title: Vasopressin excess and hyponatremia.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20060501
Title: Vaptans and the treatment of water-retaining disorders.
Journal: Seminars in nephrology 20060501
Title: Vasopressin receptor antagonists: pharmacological tools and potential therapeutic agents.
Journal: Autonomic & autacoid pharmacology 20060401
Title: Pharmacologic chaperones as a potential treatment for X-linked nephrogenic diabetes insipidus.
Journal: Journal of the American Society of Nephrology : JASN 20060101
Title: Conivaptan: a selective vasopressin antagonist for the treatment of heart failure.
Journal: Expert review of cardiovascular therapy 20060101
Title: New drugs: rasagiline mesylate, conivaptan hydrochloride, and sunitinib malate.
Journal: Journal of the American Pharmacists Association : JAPhA 20060101
Title: New drugs for prevention, relief. How you might benefit if 3 medications win FDA approval.
Journal: Heart advisor 20051001
Title: Effects of YM218, a nonpeptide vasopressin V1A receptor-selective antagonist, on human vasopressin and oxytocin receptors.
Journal: Pharmacological research 20050301
Title: Conivaptan Yamanouchi.
Journal: Current opinion in investigational drugs (London, England : 2000) 20050301
Title: Intravenous administration of conivaptan hydrochloride improves cardiac hemodynamics in rats with myocardial infarction-induced congestive heart failure.
Journal: European journal of pharmacology 20050110
Title: Vasopressin antagonists in heart failure.
Journal: Current heart failure reports 20041201
Title: Conivaptan: YM 087.
Journal: Drugs in R&D 20040101
Title: Vasopressin receptor antagonists in heart failure.
Journal: Current opinion in pharmacology 20031201
Title: 2,5-disubstituted 3,4-dihydro-2H-benzo[b][1,4]thiazepines as potent and selective V2 arginine vasopressin receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20031117
Title: Therapeutic role of vasopressin receptor antagonism in patients with liver cirrhosis.
Journal: Clinical science (London, England : 1979) 20030701
Title: Effect of the V1a/V2-AVP receptor antagonist, Conivaptan, on renal water metabolism and systemic hemodynamics in rats with cirrhosis and ascites.
Journal: Journal of hepatology 20030601
Title: Rationale for use of an exercise end point and design for the ADVANCE (A Dose evaluation of a Vasopressin ANtagonist in CHF patients undergoing Exercise) trial.
Journal: American heart journal 20030101
Title: Effect of conivaptan, a combined vasopressin V(1a) and V(2) receptor antagonist, on vasopressin-induced cardiac and haemodynamic changes in anaesthetised dogs.
Journal: Pharmacological research 20021101
Title: Effect of the vasopressin receptor antagonist conivaptan in rats with heart failure following myocardial infarction.
Journal: European journal of pharmacology 20020823
Title: [Treatment of heart failure: an update].
Journal: Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20020701
Title: Vasopressin antagonists in CHF: ready for clinical trials?
Journal: Cardiovascular research 20020401
Title: Neurohormonal antagonism in heart failure; beneficial effects of vasopressin V(1a) and V(2) receptor blockade and ACE inhibition.
Journal: Cardiovascular research 20020401
Title: Body compartment volumes and composition after giving a vasopressin antagonist: changes are revealed by a tonicity balance.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020201
Title: Conivaptan (Yamanouchi).
Journal: Current opinion in investigational drugs (London, England : 2000) 20020101
Title: Molecular modeling of interactions of the non-peptide antagonist YM087 with the human vasopressin V1a, V2 receptors and with oxytocin receptors.
Journal: Journal of computer-aided molecular design 20011201
Title: Acute hemodynamic effects of conivaptan, a dual V(1A) and V(2) vasopressin receptor antagonist, in patients with advanced heart failure.
Journal: Circulation 20011113
Title: Long-term treatment of patients with inappropriate secretion of antidiuretic hormone by the vasopressin receptor antagonist conivaptan, urea, or furosemide.
Journal: The American journal of medicine 20010501
Title: Pharmacological characterization of the human vasopressin receptor subtypes stably expressed in Chinese hamster ovary cells.
Journal: British journal of pharmacology 19981201
Title: Pharmacological characterization of YM087, a potent, nonpeptide human vasopressin V1A and V2 receptor antagonist.
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