Home Amines 169505-93-5
169505-93-5,MFCD09971032
Catalog No.:AA00AKNH

169505-93-5 | (N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE

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5mg
≥98%
in stock  
$158.00   $110.00
- +
10mg
≥98%
in stock  
$250.00   $175.00
- +
25mg
98% by HPLC
in stock  
$473.00   $331.00
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50mg
98% by HPLC
in stock  
$761.00   $533.00
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100mg
98% by HPLC
in stock  
$1,270.00   $889.00
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500mg
98% by HPLC
in stock  
$3,958.00   $2,771.00
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1000mg
98% by HPLC
in stock  
$6,295.00   $4,407.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00AKNH
Chemical Name:
(N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE
CAS Number:
169505-93-5
Molecular Formula:
C24H30Cl2N2O2
Molecular Weight:
449.4132
MDL Number:
MFCD09971032
SMILES:
Clc1ccc2c(c1)c(c[nH]2)CC(NCCOc1ccccc1OCC1CC1)(C)C.Cl
Properties
Computed Properties
 
Complexity:
513  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
10  

Literature

Title: Identification of alpha 1L-adrenoceptor in mice and its abolition by alpha 1A-adrenoceptor gene knockout.

Journal: British journal of pharmacology 20081201

Title: Noradrenergic vasoconstriction of pig prostatic small arteries.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20080201

Title: Alpha(1A/L)-adrenoceptors mediate contraction of the circular smooth muscle of the pig urethra.

Journal: Autonomic & autacoid pharmacology 20061001

Title: Selective agonists reveal alpha(1A)- and alpha(1B)-adrenoceptor subtypes in caudal artery of the young rat.

Journal: Autonomic & autacoid pharmacology 20061001

Title: Alpha1L-adrenoceptors mediate contractions of the isolated mouse prostate.

Journal: European journal of pharmacology 20060701

Title: Different roles of alpha1-adrenoceptor subtypes in mediating cardiomyocyte protein synthesis in neonatal rats.

Journal: Clinical and experimental pharmacology & physiology 20040901

Title: alpha1A-adrenergic receptor mediated pressor response to phenylephrine in anesthetized rat.

Journal: Science in China. Series C, Life sciences 20040201

Title: Functional alpha1-adrenergic receptor subtypes in human right gastroepiploic artery.

Journal: Acta pharmacologica Sinica 20030401

Title: RS-17053 (N-[2-(2-cyclopropylmethoxyphenoxy)ethyl]-5-chloro-alpha, alpha-dimethyl-1H-indole-3-ethanamine hydrochloride), a selective alpha 1A-adrenoceptor antagonist, displays low affinity for functional alpha 1-adrenoceptors in human prostate: implications for adrenoceptor classification.

Journal: Molecular pharmacology 19960201

Title: Ford AP, et al. RS-17053 (N--(2-cyclopropylmethoxyphenoxy)ethyl-5-chloro-alpha, alpha-dimethyl-1H-indole-3-ethanamine hydrochloride), a selective alpha 1A-adrenoceptor antagonist, displays low affinity for functional alpha 1-adrenoceptors in human prostate: implications for adrenoceptor classification. Mol Pharmacol. 1996 Feb;49(2):209-15.

Title: Wellman PJ, et al. Effects of the alpha 1a-adrenoceptor antagonist RS-17053 on phenylpropanolamine-induced anorexia in rats. Pharmacol Biochem Behav. 1997 May-Jun;57(1-2):281-4.

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Tags:169505-93-5 Molecular Formula|169505-93-5 MDL|169505-93-5 SMILES|169505-93-5 (N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE