Home Amines 18076-61-4
18076-61-4,MFCD00962622
Catalog No.:AA00229G

18076-61-4 | 1H-1,2,3-Benzotriazol-4-amine hydrochloride

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1mg
>95%
1 week  
$299.00   $209.00
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5mg
>95%
1 week  
$319.00   $223.00
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10mg
>95%
1 week  
$358.00   $250.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00229G
Chemical Name:
1H-1,2,3-Benzotriazol-4-amine hydrochloride
CAS Number:
18076-61-4
Molecular Formula:
C6H6N4
Molecular Weight:
134.1386
MDL Number:
MFCD00962622
SMILES:
Nc1cccc2c1[nH]nn2
Properties
Properties
 
Form:
Solid  
MP:
148-150℃  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
127  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
XLogP3:
0.3  

Downstream Synthesis Route

[1]Patent:US2010/160360,2010,A1.Locationinpatent:Page/Pagecolumn14

[2]JustusLiebigsAnnalenderChemie,1934,vol.511,p.213,240

[3]IlFarmaco,1992,vol.47,p.1001-1019

[4]CollectionofCzechoslovakChemicalCommunications,1992,vol.57,p.531-539

[5]Patent:WO2004/33440,2004,A1.Locationinpatent:Page211-212

[6]Patent:US2004/147559,2004,A1.Locationinpatent:Page103

[7]Patent:US2004/106794,2004,A1.Locationinpatent:Page105-106

[8]Patent:WO2005/66147,2005,A1.Locationinpatent:Page/Pagecolumn182

[9]Patent:WO2005/68460,2005,A1.Locationinpatent:Page/Pagecolumn185

[1]JournalofOrganicChemistry,1992,vol.57,p.190-195

6299-39-4   
argon 
  18076-61-4 

[1]Patent:US6300325,2001,B1

6299-39-4    18076-61-4   
N-(1H-benzod1,2,3triazol-4-yl)hydroxylamine 

[1]TetrahedronLetters,2017,vol.58,p.82-86

Literature

Title: Boosting of HIV protease inhibitors by ritonavir in the intestine: the relative role of cytochrome P450 and P-glycoprotein inhibition based on Caco-2 monolayers versus in situ intestinal perfusion in mice.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20120801

Title: The genotoxic potential of methapyrilene using the alkaline Comet assay in vitro and in vivo.

Journal: Toxicology 20111218

Title: Metabolism-dependent hepatotoxicity of amodiaquine in glutathione-depleted mice.

Journal: Archives of toxicology 20090701

Title: Bioactivation of fluorotelomer alcohols in isolated rat hepatocytes.

Journal: Chemico-biological interactions 20090212

Title: Allylnitrile metabolism by CYP2E1 and other CYPs leads to distinct lethal and vestibulotoxic effects in the mouse.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090201

Title: Cadmium generates reactive oxygen- and carbon-centered radical species in rats: insights from in vivo spin-trapping studies.

Journal: Free radical biology & medicine 20080815

Title: Prostaglandins inhibit cytochrome P450 4A activity and contribute to endotoxin-induced hypotension in rats via nitric oxide production.

Journal: Archives of pharmacal research 20080701

Title: Saturable uptake of lipophilic amine drugs into isolated hepatocytes: mechanisms and consequences for quantitative clearance prediction.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070801

Title: Uptake and intracellular binding of lipophilic amine drugs by isolated rat hepatocytes and implications for prediction of in vivo metabolic clearance.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20061101

Title: Inhibition by nitric oxide of cytochrome P450 4A activity contributes to endotoxin-induced hypotension in rats.

Journal: Nitric oxide : biology and chemistry 20060201

Title: Metabolic products and pathways of fluorotelomer alcohols in isolated rat hepatocytes.

Journal: Chemico-biological interactions 20050815

Title: The use of the suicide CYP450 inhibitor ABT for distinguishing absorption and metabolism processes in in-vivo pharmacokinetic screens.

Journal: European journal of drug metabolism and pharmacokinetics 20050101

Title: Contribution of renal oxygenases to glycerol-induced acute renal failure in the rat.

Journal: Journal of cardiovascular pharmacology 20020601

Title: Toxicity of a sevoflurane degradation product incubated with rat liver and renal cortical slices.

Journal: Drug and chemical toxicology 20011101

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Tags:18076-61-4 Molecular Formula|18076-61-4 MDL|18076-61-4 SMILES|18076-61-4 1H-1,2,3-Benzotriazol-4-amine hydrochloride