Home Indole and Oxindoles 1821-52-9
1821-52-9,MFCD00005642
Catalog No.:AA0023B6

1821-52-9 | Dl-indole-3-lactic acid

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50mg
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100mg
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$103.00   $72.00
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500mg
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$342.00   $239.00
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1g
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5g
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0023B6
Chemical Name:
Dl-indole-3-lactic acid
CAS Number:
1821-52-9
Molecular Formula:
C11H11NO3
Molecular Weight:
205.2099
MDL Number:
MFCD00005642
SMILES:
OC(=O)C(Cc1c[nH]c2c1cccc2)O
Properties
Properties
 
BP:
477.3°C at 760 mmHg  
Form:
Solid  
MP:
145-146 °C(lit.)  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
244  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
1  
XLogP3:
1.5  

Downstream Synthesis Route

[1]CurrentPatentAssignee:DEBIOPHARMINTERNATIONALSA-US6762201,2004,B1Locationinpatent:Page/Pagecolumn17

[1]CurrentPatentAssignee:TAKEDAPHARMACEUTICALCOMPANYLIMITED-US2003/144338,2003,A1

[1]Busto,Eduardo;Grischek,Barbara;Kroutil,Wolfgang;Richter,Nina[Chemistry-AEuropeanJournal,2014,vol.20,#35,p.11225-11228,4]

[1]CurrentPatentAssignee:NATIONALCENTERFORGERIATRICSANDGERONTOLOGY-EP3275440,2018,A1Locationinpatent:Paragraph0186;0187

[1]CurrentPatentAssignee:NATIONALCENTERFORGERIATRICSANDGERONTOLOGY-EP3275440,2018,A1Locationinpatent:Paragraph0177;0178

Literature

Title: Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics.

Journal: Scientific reports 20180101

Title: Metabolomic analysis of biochemical changes in the plasma and urine of collagen-induced arthritis in rats after treatment with Huang-Lian-Jie-Du-Tang.

Journal: Journal of ethnopharmacology 20140528

Title: Indole derivative production by the root endophyte Piriformospora indica is not required for growth promotion but for biotrophic colonization of barley roots.

Journal: The New phytologist 20121001

Title: Impact of short-term intake of red wine and grape polyphenol extract on the human metabolome.

Journal: Journal of agricultural and food chemistry 20120328

Title: A 'crossomics' study analysing variability of different components in peripheral blood of healthy caucasoid individuals.

Journal: PloS one 20120101

Title: Electrospray ionization mass spectrometry: a technique to access the information beyond the molecular weight of the analyte.

Journal: International journal of analytical chemistry 20120101

Title: Metabonomics biomarkers for subacute toxicity screening for benzene exposure in mice.

Journal: Journal of toxicology and environmental health. Part A 20120101

Title: Mechanism-based pharmacokinetic-pharmacodynamic modeling of the estrogen-like effect of ginsenoside Rb1 on neural 5-HT in ovariectomized mice.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20110918

Title: UPLC-MS-based urine metabolomics reveals indole-3-lactic acid and phenyllactic acid as conserved biomarkers for alcohol-induced liver disease in the Ppara-null mouse model.

Journal: Journal of proteome research 20110902

Title: Metabolomics analysis reveals elevation of 3-indoxyl sulfate in plasma and brain during chemically-induced acute kidney injury in mice: investigation of nicotinic acid receptor agonists.

Journal: Toxicology and applied pharmacology 20110815

Title: Cold-adapted and rhizosphere-competent strain of Rahnella sp. with broad-spectrum plant growth-promotion potential.

Journal: Journal of microbiology and biotechnology 20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Identification of noninvasive biomarkers for alcohol-induced liver disease using urinary metabolomics and the Ppara-null mouse.

Journal: Journal of proteome research 20100806

Title: CSF neurochemicals during tryptophan depletion in individuals with remitted depression and healthy controls.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20100101

Title: Enantioselective oxidation of 2-hydroxy carboxylic acids by glycolate oxidase and catalase coexpressed in methylotrophic Pichia pastoris.

Journal: Biotechnology progress 20100101

Title: Automatic assignment of EC numbers.

Journal: PLoS computational biology 20100101

Title: Plasma metabolomic profiles reflective of glucose homeostasis in non-diabetic and type 2 diabetic obese African-American women.

Journal: PloS one 20100101

Title: Rapid Isocratic Liquid Chromatographic Separation and Quantification of Tryptophan and Six kynurenine Metabolites in Biological Samples with Ultraviolet and Fluorimetric Detection.

Journal: International journal of tryptophan research : IJTR 20100101

Title: Structural insight into the inhibition of human kynurenine aminotransferase I/glutamine transaminase K.

Journal: Journal of medicinal chemistry 20090514

Title: Serotonin transporter is differentially localized in subpopulations of lymphocytes of major depression patients. Effect of fluoxetine on proliferation.

Journal: Journal of neuroimmunology 20080530

Title: Isolation and cytotoxicity of low-molecular-weight metabolites of Candida albicans.

Journal: Frontiers in bioscience : a journal and virtual library 20080501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Indole derivatives produced by the fungus Colletotrichum acutatum causing lime anthracnose and postbloom fruit drop of citrus.

Journal: FEMS microbiology letters 20030912

Title: Effect of steroid injection to newborn rats on serotonin activity in frontal cortex and raphe.

Journal: Neuroreport 20030324

Title: Higher plasma 5-hydroxyindoleacetic acid levels are associated with SSRI-induced nausea.

Journal: Neuropsychobiology 20030101

Title: Evaluation and application of liquid chromatographic columns coated with 'intelligent' ligands: (I) acylcarnitine column.

Journal: Journal of chromatography. A 20010921

Title: Chemically L-prolinamide-modified monolithic silica column for enantiomeric separation of dansyl amino acids and hydroxy acids by capillary electrochromatography and mu-high performance liquid chromatography.

Journal: Electrophoresis 20010901

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SDS
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