Home Amines 183319-69-9
183319-69-9,MFCD07781272
Catalog No.:AA0027FC

183319-69-9 | N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
98%
in stock  
$27.00   $19.00
- +
5g
98%
in stock  
$33.00   $23.00
- +
10g
98%
in stock  
$63.00   $44.00
- +
25g
97%
in stock  
$103.00   $73.00
- +
100g
97%
in stock  
$378.00   $264.00
- +
  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0027FC
Chemical Name:
N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride
CAS Number:
183319-69-9
Molecular Formula:
C22H24ClN3O4
Molecular Weight:
429.8967
MDL Number:
MFCD07781272
SMILES:
COCCOc1cc2c(ncnc2cc1OCCOC)Nc1cccc(c1)C#C.Cl
NSC Number:
718781
Properties
Computed Properties
 
Complexity:
525  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
11  

Literature

Title: Moyer JD, et al. Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res. 1997 Nov 1;57(21):4838-48.

Title: Ali S, et al. Apoptosis-inducing effect of erlotinib is potentiated by 3,3'-diindolylmethane in vitro and in vivo using an orthotopic model of pancreatic cancer. Mol Cancer Ther, 2008, 7(6), 1708-1719.

Title: Marchetti S, et al. Effect of the ATP-binding cassette drug transporters ABCB1, ABCG2, and ABCC2 on erlotinib hydrochloride (Tarceva) disposition in in vitro and in vivo pharmacokinetic studies employing Bcrp1-/-/Mdr1a/1b-/- (triple-knockout) and wild-typ

Title: Adachi K, et al. Effects of erlotinib on lung injury induced by intratracheal administration of bleomycin (BLM) in rats. J Toxicol Sci. 2010 Aug;35(4):503-14.

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SDS
Tags:183319-69-9 Molecular Formula|183319-69-9 MDL|183319-69-9 SMILES|183319-69-9 N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride