Home Other Building Blocks 18997-57-4
18997-57-4,MFCD00063694
Catalog No.:AA002E4L

18997-57-4 | 4-Methylumbelliferyl β-D-glucopyranoside

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
>98.0%(HPLC)
in stock  
$30.00   $21.00
- +
1g
98%
in stock  
$56.00   $39.00
- +
5g
99%
in stock  
$106.00   $75.00
- +
25g
≥ 98% (HPLC)
in stock  
$476.00   $333.00
- +
100g
≥ 98% (HPLC)
in stock  
$1,620.00   $1,134.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA002E4L
Chemical Name:
4-Methylumbelliferyl β-D-glucopyranoside
CAS Number:
18997-57-4
Molecular Formula:
C16H18O8
Molecular Weight:
338.3093
MDL Number:
MFCD00063694
SMILES:
OC[C@H]1O[C@@H](Oc2ccc3c(c2)oc(=O)cc3C)[C@@H]([C@H]([C@@H]1O)O)O
Properties
Computed Properties
 
Complexity:
506  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
3  
XLogP3:
-0.8  

Downstream Synthesis Route

[1]Wei,Xianhu;Ma,Yanxia;Wu,Qingping;Zhang,Jumei;Cai,Zhihe;Lu,Mianfei;Ferro,Vito[Molecules,2015,vol.20,#12,p.21681-21699]

[2]CurrentPatentAssignee:GUANGDONGACADEMYOFSCIENCES;GUANGDONGHUANKAIMICROBIALSCI&TECHNOLOGYCOLTD-CN104926898,2018,BLocationinpatent:Paragraph0080;0081

[3]Locationinpatent:experimentalpartTouisni,Nadia;Maresca,Alfonso;McDonald,PaulC.;Lou,Yuanmei;Scozzafava,Andrea;Dedhar,Shoukat;Winum,Jean-Yves;Supuran,ClaudiuT.[JournalofMedicinalChemistry,2011,vol.54,#24,p.8271-8277]

[4]Robinson[BiochemicalJournal,1956,vol.63,p.39,40]

[5]Constantzas;Kocourek[CollectionofCzechoslovakChemicalCommunications,1959,vol.24,p.1099,1102]

[6]DaReetal.[AnnalidiChimica,1959,vol.49,p.2089,2095]

[7]Malet,Carles;Viladot,JosepLluis;Ochoa,Ana;Gallego,Belen;Brosa,Carme;Planas,Antoni[CarbohydrateResearch,1995,vol.274,p.285-302]

[8]St-Pierre,Gabrielle;Dafik,Laila;Klegraf,Ellen;Hanessian,Stephen[Synthesis,2016,vol.48,#20,p.3575-3588]

[1]Marsh;Levy[Nature,1956,vol.178,p.589]

[2]López-López,MiguelA.;Balbuzano-Deus,Alexander;Rodríguez-Domínguez,JuanC.;Hernández,MiriamMesa;Villalobo,AnaisFernández;Reyes,YulianelaIbarra;Kirsch,Gilbert[Synlett,2007,#4,p.649-651]

[1]Amess,Robert;Baggett,Neil;Darby,PaulR.;Goode,AnthonyR.;Vickers,ErnestE.[CarbohydrateResearch,1990,vol.205,#1,p.225-233]

[2]Suthangkornkul,Rungarun;Sriworanun,Pornpisut;Nakai,Hiroyuki;Okuyama,Masayuki;Svasti,Jisnuson;Kimura,Atsuo;Senapin,Saengchan;Arthan,Dumrongkiet[Phytochemistry,2016,vol.127,p.4-11]

[1]Malet,Carles;Viladot,JosepLluis;Ochoa,Ana;Gallego,Belen;Brosa,Carme;Planas,Antoni[CarbohydrateResearch,1995,vol.274,p.285-302]

Literature

Title: Algorithm for Pompe disease newborn screening: results from the Taiwan screening program.

Journal: Molecular genetics and metabolism 20120701

Title: Glycosyl coumarin carbonic anhydrase IX and XII inhibitors strongly attenuate the growth of primary breast tumors.

Journal: Journal of medicinal chemistry 20111222

Title: Newborn screening for Pompe disease in Japan.

Journal: Molecular genetics and metabolism 20111201

Title: Using simple donors to drive the equilibria of glycosyltransferase-catalyzed reactions.

Journal: Nature chemical biology 20111001

Title: Biomarkers in the diagnosis of lysosomal storage disorders: proteins, lipids, and inhibodies.

Journal: Journal of inherited metabolic disease 20110601

Title: Bioinformatic and biochemical studies point to AAGR-1 as the ortholog of human acid alpha-glucosidase in Caenorhabditis elegans.

Journal: Molecular and cellular biochemistry 20100801

Title: High-level production of a thermoacidophilic beta-glucosidase from Penicillium citrinum YS40-5 by solid-state fermentation with rice bran.

Journal: Bioresource technology 20100201

Title: Scopolin-hydrolyzing beta-glucosidases in roots of Arabidopsis.

Journal: Plant & cell physiology 20100101

Title: Endoplasmic reticulum stress underlying the pro-apoptotic effect of epigallocatechin gallate in mouse hepatoma cells.

Journal: The international journal of biochemistry & cell biology 20090301

Title: A sensitive and reproducible fluorescent-based HPLC assay to measure the activity of acid as well as neutral beta-glucocerebrosidases.

Journal: Analytical biochemistry 20081201

Title: Optimization and validation of two miniaturized glucocerebrosidase enzyme assays for high throughput screening.

Journal: Combinatorial chemistry & high throughput screening 20081201

Title: A pseudo-beta-glucosidase in Arabidopsis thaliana: correction by site-directed mutagenesis, heterologous expression, purification, and characterization.

Journal: Biochemistry. Biokhimiia 20080801

Title: Development of sensitive chemical and immunochemical methods for detecting sulfated sialic acids and their application to glycoconjugates from sea urchin sperm and eggs.

Journal: Biochimie 20071101

Title: Expanding the promiscuity of a natural-product glycosyltransferase by directed evolution.

Journal: Nature chemical biology 20071001

Title: The interplay of processivity, substrate inhibition and a secondary substrate binding site of an insect exo-beta-1,3-glucanase.

Journal: Biochimica et biophysica acta 20070901

Title: Characterization of a beta-glucosidase produced by a high-specific growth-rate mutant of Cellulomonas flavigena.

Journal: Current microbiology 20070401

Title: Evaluation of novel fluorogenic substrates for the detection of glycosidases in Escherichia coli and enterococci.

Journal: Journal of applied microbiology 20061101

Title: beta-Glucosidase catalyzing specific hydrolysis of an iridoid beta-glucoside from Plumeria obtusa.

Journal: Acta biochimica et biophysica Sinica 20060801

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Benign course of glycogen storage disease type IIb in two brothers: nature or nurture?

Journal: Muscle & nerve 20060401

Title: Furostanol glycoside 26-O-beta-glucosidase from the leaves of Solanum torvum.

Journal: Phytochemistry 20060101

Title: Purification and characterization of an intracellular beta-glucosidase from the methylotrophic yeast Pichia pastoris.

Journal: Biochemistry. Biokhimiia 20051201

Title: Study of beta-glucosidase production by wine-related yeasts during alcoholic fermentation. A new rapid fluorimetric method to determine enzymatic activity.

Journal: Journal of applied microbiology 20050101

Title: Hydrolase and glycosynthase activity of endo-1,3-beta-glucanase from the thermophile Pyrococcus furiosus.

Journal: Archaea (Vancouver, B.C.) 20041001

Title: Fluorescent screening of transgenic Arabidopsis seeds without germination.

Journal: Plant physiology 20040601

Title: Analysis of recombinant human saposin A expressed by Pichia pastoris.

Journal: Biochemical and biophysical research communications 20040528

Title: Expression and functional characterization of mutated glucocerebrosidase alleles causing Gaucher disease in Spanish patients.

Journal: Blood cells, molecules & diseases 20040101

Title: Mechanism of the hydrolysis of 4-methylumbelliferyl-beta-D-glucoside by germinating and outgrowing spores of Bacillus species.

Journal: Journal of applied microbiology 20040101

Title: A medium for the presumptive detection of Enterobacter sakazakii in infant formula: interlaboratory study.

Journal: Journal of AOAC International 20040101

Title: Cloning and characterization of two alpha-glucosidases from Bifidobacterium adolescentis DSM20083.

Journal: Applied microbiology and biotechnology 20030301

Title: A beta-glucosidase/xylosidase from the phytopathogenic oomycete, Phytophthora infestans.

Journal: Phytochemistry 20020401

Title: Heterologous expression and characterization of a rare Gaucher disease mutation (c.481C > T) from a Canadian aboriginal population using archival tissue samples.

Journal: Molecular genetics and metabolism 20011101

Title: Extracellular enzyme activities during slow sand filtration in a water recharge plant.

Journal: Water research 20010701

Title: Translocon pores in the endoplasmic reticulum are permeable to a neutral, polar molecule.

Journal: The Journal of biological chemistry 20010622

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:18997-57-4 Molecular Formula|18997-57-4 MDL|18997-57-4 SMILES|18997-57-4 4-Methylumbelliferyl β-D-glucopyranoside