Title: Orally active MMP-1 sparing α-tetrahydropyranyl and α-piperidinyl sulfone matrix metalloproteinase (MMP) inhibitors with efficacy in cancer, arthritis, and cardiovascular disease.
Journal: Journal of medicinal chemistry 20100923
Title: Hydroxamates: relationships between structure and plasma stability.
Journal: Journal of medicinal chemistry 20091112
Title: Discovery of potent, selective, and orally active carboxylic acid based inhibitors of matrix metalloproteinase-13.
Journal: Journal of medicinal chemistry 20090611
Title: Synthesis and structure-activity relationship of N-substituted 4-arylsulfonylpiperidine-4-hydroxamic acids as novel, orally active matrix metalloproteinase inhibitors for the treatment of osteoarthritis.
Journal: Journal of medicinal chemistry 20030605
Title: Protease inhibitors: current status and future prospects.
Journal: Journal of medicinal chemistry 20000210
Title: Kahraman A, et al. Matrix metalloproteinase inhibitor, CTS-1027, attenuates liver injury and fibrosis in the bile duct-ligated mouse. Hepatol Res. 2009 Aug;39(8):805-813.
Title: Johnson JL, et al. Effect of broad-spectrum matrix metalloproteinase inhibition on atherosclerotic plaque stability. Cardiovasc Res. 2006 Aug 1;71(3):586-595.
