Title: Apricoxib, a novel inhibitor of COX-2, markedly improves standard therapy response in molecularly defined models of pancreatic cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120915
Title: Epithelial-mesenchymal transition increases tumor sensitivity to COX-2 inhibition by apricoxib.
Journal: Carcinogenesis 20120901
Title: Apricoxib upregulates 15-PGDH and PGT in tobacco-related epithelial malignancies.
Journal: British journal of cancer 20120807
Title: Sulfonamides: a patent review (2008 - 2012).
Journal: Expert opinion on therapeutic patents 20120701
Title: First-line treatment of metastatic pancreatic cancer.
Journal: JOP : Journal of the pancreas 20120310
Title: Efficient synthesis of apricoxib, CS-706, a selective cyclooxygenase-2 inhibitor, and evaluation of inhibition of prostaglandin E2 production in inflammatory breast cancer cells.
Journal: Bioorganic & medicinal chemistry letters 20111015
Title: Translational research in pancreatic cancer. Highlights from the '2011 ASCO Gastrointestinal Cancers Symposium'. San Francisco, CA, USA. January 20-22, 2011.
Journal: JOP : Journal of the pancreas 20110309
Title: Biomarker-based phase I dose-escalation, pharmacokinetic, and pharmacodynamic study of oral apricoxib in combination with erlotinib in advanced nonsmall cell lung cancer.
Journal: Cancer 20110215
Title: Apricoxib, a COX-2 inhibitor for the potential treatment of pain and cancer.
Journal: IDrugs : the investigational drugs journal 20091101
Title: Pain relief model for a COX-2 inhibitor in patients with postoperative dental pain.
Journal: British journal of clinical pharmacology 20080701
Title: CS-706, a novel cyclooxygenase-2 selective inhibitor, prolonged the survival of tumor-bearing mice when treated alone or in combination with anti-tumor chemotherapeutic agents.
Journal: International journal of cancer 20080315
Title: Preclinical pharmacology profile of CS-706, a novel cyclooxygenase-2 selective inhibitor, with potent antinociceptive and anti-inflammatory effects.
Journal: European journal of pharmacology 20080106
Title: Gastroduodenal defense.
Journal: Current opinion in gastroenterology 20071101
Title: Therapeutic effect of CS-706, a specific cyclooxygenase-2 inhibitor, on gallbladder carcinoma in BK5.ErbB-2 mice.
Journal: Molecular cancer therapeutics 20070601
Title: Predictive population pharmacokinetic/pharmacodynamic model for a novel COX-2 inhibitor.
Journal: Journal of clinical pharmacology 20070301
Title: A randomized, double-blind, celecoxib- and placebo-controlled study of the effectiveness of CS-706 in acute postoperative dental pain.
Journal: Clinical therapeutics 20070301
Title: A randomized, double-blind, one-week study comparing effects of a novel COX-2 inhibitor and naproxen on the gastric mucosa.
Journal: Digestive diseases and sciences 20070201
Title: Covalent binding of radioactivity from [14C]rofecoxib, but not [14C]celecoxib or [14C]CS-706, to the arterial elastin of rats.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20060801
Title: Development of a predictive pharmacokinetic model for a novel cyclooxygenase-2 inhibitor.
Journal: Journal of clinical pharmacology 20060501
