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20170-32-5,MFCD00017519
Catalog No.:AA0073H0

20170-32-5 | 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionic acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
25g
97%
in stock  
$8.00   $6.00
- +
100g
97%
in stock  
$27.00   $19.00
- +
500g
97%
in stock  
$117.00   $82.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0073H0
Chemical Name:
3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionic acid
CAS Number:
20170-32-5
Molecular Formula:
C17H26O3
Molecular Weight:
278.3865
MDL Number:
MFCD00017519
SMILES:
OC(=O)CCc1cc(c(c(c1)C(C)(C)C)O)C(C)(C)C
Properties
Computed Properties
 
Complexity:
311  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
5  
XLogP3:
4.7  

Upstream Synthesis Route

[1]TetrahedronLetters,2013,vol.54,#25,p.3294-3297

[2]RussianChemicalBulletin,2007,vol.56,#6,p.1119-1124

[1]PharmaceuticalChemistryJournal,2000,vol.34,#5,p.273-275

[1]JournalofMedicinalChemistry,2000,vol.43,#15,p.2779-2782

[1]ACSMedicinalChemistryLetters,2014,vol.5,#7,p.742-747

[2]JournaloftheAmericanChemicalSociety,1957,vol.79,p.5019,5021

[1]Patent:US4713475,1987,A,

[2]BulletinoftheAcademyofSciencesoftheUSSR,DivisionofChemicalScience(EnglishTranslation),1982,vol.31,#7,p.1417-1420

[3]IzvestiyaAkademiiNaukSSSR,SeriyaKhimicheskaya,1982,#7,p.1594-1597

[4]Patent:CN104211616,2016,B,.Locationinpatent:Paragraph0064-0066

Downstream Synthesis Route

[1]JournaloftheAmericanChemicalSociety,1957,vol.79,p.5019,5021

[1]ACSMedicinalChemistryLetters,2014,vol.5,p.742-747

[2]JournaloftheAmericanChemicalSociety,1957,vol.79,p.5019,5021

20170-32-5    61629-90-1   
3-(4-{2-3-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-propionylamino-ethyl}-phenyl)-propionicacid 

[1]Patent:DD124974,1977,    Patent:DE2604560,1977,    Chem.Abstr.,1977,vol.87

20170-32-5    100204-33-9   
3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionicacid,1-(3,5-di-tert-butyl-4-hydroxyphenylthio)methylester 

[1]PhosphorusandSulfurandtheRelatedElements,1987,vol.29,p.67-72

[1]RSCAdvances,2014,vol.4,p.41763-41771

[2]PhosphorusandSulfurandtheRelatedElements,1987,vol.29,p.67-72

[3]JournalofMedicinalChemistry,2000,vol.43,p.2779-2782

[4]RussianJournalofOrganicChemistry,2014,vol.50,p.371-375    Zh.Org.Khim.,2014,vol.50,p.382-386,5

[5]ACSMedicinalChemistryLetters,2014,vol.5,p.742-747

[6]Patent:US2017/334821,2017,A1.Locationinpatent:Paragraph0042;0045;0060

[7]RussianChemicalBulletin,2018,vol.67,p.2025-2034    Izv.Akad.Nauk,Ser.Khim.,2018,vol.11,p.2025-2034,10

[8]Patent:CN110407714,2019,A.Locationinpatent:Paragraph0043;0054-0057

Literature

Title: Time- and temperature-dependent migration studies of Irganox 1076 from plastics into foods and food simulants.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Water solutions of phenosan potassium salt: influence on biological membrane structure and conductivity.

Journal: Doklady. Biochemistry and biophysics 20090101

Title: [The effects of antioxidants on the reflex from an eye-ground and electric activity of retina during intravitreal haemorrhage].

Journal: Georgian medical news 20081001

Title: [Effect of antioxidant beta-(4-hydroxy-3,5-ditertbutylphenyl) propionic acid (phenosan) on the development of malignant neoplasms].

Journal: Izvestiia Akademii nauk. Seriia biologicheskaia 20070101

Title: Blood schizontocidal activity of selected 1,2,4-trioxanes (Fenozans) against the multidrug-resistant strain of Plasmodium yoelii nigeriensis (MDR) in vivo.

Journal: Parasitology 20060701

Title: [The interrelation of chemical structure and inhibiting action of the stericly hindered phenols of ichfan groups].

Journal: Biomeditsinskaia khimiia 20050101

Title: [The influence of pharmacologically active substances of different classes at ultra low doses on lipid peroxidation in brain cell membranes and activity of acetylcholinesterase in vivo and in vitro].

Journal: Radiatsionnaia biologiia, radioecologiia 20030101

Title: [On the 'receptor' mechanism of the effect of biologically active substances in ultra low concentrations].

Journal: Radiatsionnaia biologiia, radioecologiia 20030101

Title: [Effect of low doses of phenozan on lactate dehydrogenase and microviscosity of microsomal membranes of brain cells in mice].

Journal: Radiatsionnaia biologiia, radioecologiia 20030101

Title: [Mechanism of polymorphic transformations in phosphatidylcholine membranes].

Journal: Biofizika 20020101

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SDS
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