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20187-55-7,MFCD00866158
Catalog No.:AA0027TY

20187-55-7 | 2-[(1-benzyl-1H-indazol-3-yl)oxy]acetic acid

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Purity
Availability
Price(USD)
Quantity
  
1g
98%(HPLC)
in stock  
$24.00   $17.00
- +
5g
98%
in stock  
$54.00   $38.00
- +
25g
98%
in stock  
$112.00   $78.00
- +
100g
98%
in stock  
$311.00   $218.00
- +
500g
98%
in stock  
$1,142.00   $799.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0027TY
Chemical Name:
2-[(1-benzyl-1H-indazol-3-yl)oxy]acetic acid
CAS Number:
20187-55-7
Molecular Formula:
C16H14N2O3
Molecular Weight:
282.2940
MDL Number:
MFCD00866158
SMILES:
OC(=O)COc1nn(c2c1cccc2)Cc1ccccc1
Properties
Properties
 
BP:
508.2°C at 760 mmHg  
Form:
Solid  
MP:
161-163 °C  
Refractive Index:
1.6240 (estimate)  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
357  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  
XLogP3:
3.1  

Literature

Title: Discriminating between adaptive and carcinogenic liver hypertrophy in rat studies using logistic ridge regression analysis of toxicogenomic data: The mode of action and predictive models.

Journal: Toxicology and applied pharmacology 20170301

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: Synthesis and biological evaluations of novel bendazac lysine analogues as potent anticataract agents.

Journal: Bioorganic & medicinal chemistry letters 20100401

Title: Gene expression profiling in rat liver treated with compounds inducing elevation of bilirubin.

Journal: Human & experimental toxicology 20090401

Title: Advances in pharmacological strategies for the prevention of cataract development.

Journal: Indian journal of ophthalmology 20090101

Title: Topical ocular delivery of NSAIDs.

Journal: The AAPS journal 20080601

Title: Medical treatment of cataract.

Journal: Clinical & experimental ophthalmology 20070101

Title: Bendazac lysine inhibition of human lens epithelial cell adhesion to polymethylmethacrylate intraocular lenses.

Journal: Ophthalmic research 20040101

Title: Antidenaturant drugs for cataract and other condensation diseases.

Journal: Medical hypotheses 20010101

Title: Balfour JA, et al. Bendazac lysine. A review of its pharmacological properties and therapeutic potential in the management of cataracts. Drugs. 1990;39(4):575-596.

Title: Guglielmotti A, et al. Radical scavenger activity of bendazac, an anticataract non-steroidal anti-inflammatory agent. Pharmacol Res. 1995;32(6):369-373.

Title: Musci G, et al. Mechanism of the scavenger-like activity of bendazac. Drugs Exp Clin Res. 1987;13(5):289-292.

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SDS
Tags:20187-55-7 Molecular Formula|20187-55-7 MDL|20187-55-7 SMILES|20187-55-7 2-[(1-benzyl-1H-indazol-3-yl)oxy]acetic acid |Heterocyclic_Building_Blocks