Title: Perinatal exposure to low-dose of bisphenol A causes anxiety-like alteration in adrenal axis regulation and behaviors of rat offspring: a potential role for metabotropic glutamate 2/3 receptors.
Journal: Journal of psychiatric research 20150501
Title: Pharmacological characterization of JNJ-40068782, a new potent, selective, and systemically active positive allosteric modulator of the mGlu2 receptor and its radioligand [3H]JNJ-40068782.
Journal: The Journal of pharmacology and experimental therapeutics 20130901
Title: Synthesis and characterization of two PET radioligands for the metabotropic glutamate 1 (mGlu1) receptor.
Journal: Synapse (New York, N.Y.) 20121201
Title: Depolarizing bipolar cell dysfunction due to a Trpm1 point mutation.
Journal: Journal of neurophysiology 20121101
Title: mTOR activation is required for the antidepressant effects of mGluR₂/₃ blockade.
Journal: The international journal of neuropsychopharmacology 20120501
Title: Developmental regulation of CB1-mediated spike-time dependent depression at immature mossy fiber-CA3 synapses.
Journal: Scientific reports 20120101
Title: Development of GPCR modulation of GABAergic transmission in chicken nucleus laminaris neurons.
Journal: PloS one 20120101
Title: Group II metabotropic glutamate receptors depress synaptic transmission onto subicular burst firing neurons.
Journal: PloS one 20120101
Title: Involvement of the mammalian target of rapamycin signaling in the antidepressant-like effect of group II metabotropic glutamate receptor antagonists.
Journal: Neuropharmacology 20111201
Title: Excitatory amino acid transporter 2 and excitatory amino acid transporter 1 negatively regulate calcium-dependent proliferation of hippocampal neural progenitor cells and are persistently upregulated after injury.
Journal: The European journal of neuroscience 20111201
Title: Estradiol attenuates the adenosine triphosphate-induced increase of intracellular calcium through group II metabotropic glutamate receptors in rat dorsal root ganglion neurons.
Journal: Journal of neuroscience research 20111101
Title: Activation of group II metabotropic glutamate receptors induces long-term depression of excitatory synaptic transmission in the substantia nigra pars reticulata.
Journal: Neuroscience letters 20111024
Title: Blockade of GABA(B) receptors facilitates evoked neurotransmitter release at spinal dorsal horn synapse.
Journal: Neuroscience 20111013
Title: Group II/III metabotropic glutamate receptors exert endogenous activity-dependent modulation of TRPV1 receptors on peripheral nociceptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110907
Title: Functional coupling between metabotropic glutamate receptors and G-proteins in rat cerebral cortex assessed by guanosine-5'-O-(3-[(35)S]thio)triphosphate binding assay.
Journal: Basic & clinical pharmacology & toxicology 20110901
Title: The role of 5-hydroxytryptamine 7 receptors in the phencyclidine-induced novel object recognition deficit in rats.
Journal: The Journal of pharmacology and experimental therapeutics 20110801
Title: A role for nyctalopin, a small leucine-rich repeat protein, in localizing the TRP melastatin 1 channel to retinal depolarizing bipolar cell dendrites.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110706
Title: Activation of group II metabotropic glutamate receptors promotes DNA demethylation in the mouse brain.
Journal: Molecular pharmacology 20110701
Title: Regulation of Akt and Wnt signaling by the group II metabotropic glutamate receptor antagonist LY341495 and agonist LY379268.
Journal: Journal of neurochemistry 20110601
Title: Group II metabotropic glutamate receptors in the striatum of non-human primates: dysregulation following chronic cocaine self-administration.
Journal: Neuroscience letters 20110527
Title: Baclofen and adenosine inhibition of synaptic transmission at CA3-CA1 synapses display differential sensitivity to K+ channel blockade.
Journal: Cellular and molecular neurobiology 20110501
Title: Postsynaptic and presynaptic group II metabotropic glutamate receptor activation reduces neuronal excitability in rat midline paraventricular thalamic nucleus.
Journal: The Journal of pharmacology and experimental therapeutics 20110301
Title: Targeting group II metabotropic glutamate (mGlu) receptors for the treatment of psychosis associated with Alzheimer's disease: selective activation of mGlu2 receptors amplifies beta-amyloid toxicity in cultured neurons, whereas dual activation of mGlu2 and mGlu3 receptors is neuroprotective.
Journal: Molecular pharmacology 20110301
Title: Metabotropic glutamate receptor blockade in nucleus accumbens shell shifts affective valence towards fear and disgust.
Journal: The European journal of neuroscience 20110201
Title: Orally active glutamate carboxypeptidase II inhibitor 2-MPPA attenuates dizocilpine-induced prepulse inhibition deficits in mice.
Journal: Brain research 20110131
Title: AMPA receptor mediates mGlu 2/3 receptor antagonist-induced dopamine release in the rat nucleus accumbens shell.
Journal: Neurochemistry international 20101101
Title: Effects of metabotropic glutamate receptor 2/3 agonism and antagonism on schizophrenia-like cognitive deficits induced by phencyclidine in rats.
Journal: European journal of pharmacology 20100810
Title: Pharmacological effects of metabotropic glutamate receptor ligands on prepulse inhibition in DBA/2J mice.
Journal: European journal of pharmacology 20100810
Title: Metabotropic glutamate receptors modulate glutamatergic and GABAergic synaptic transmission in the central nucleus of the inferior colliculus.
Journal: Brain research 20100414
Title: Group II metabotropic glutamate receptor stimulation triggers production and release of Alzheimer's amyloid(beta)42 from isolated intact nerve terminals.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100317
Title: Oral administration of the NAALADase inhibitor GPI-5693 attenuates cocaine-induced reinstatement of drug-seeking behavior in rats.
Journal: European journal of pharmacology 20100210
Title: Excitotoxicity effects of glutamate on human neuroblastoma SH-SY5Y cells via oxidative damage.
Journal: Neuroscience bulletin 20100201
Title: Inhibition of NAALADase by 2-PMPA attenuates cocaine-induced relapse in rats: a NAAG-mGluR2/3-mediated mechanism.
Journal: Journal of neurochemistry 20100101
Title: Extinction of cued fear memory involves a distinct form of depotentiation at cortical input synapses onto the lateral amygdala.
Journal: The European journal of neuroscience 20091203
Title: Involvement of Group II mGluRs in mossy fiber LTD.
Journal: Synapse (New York, N.Y.) 20091201
Title: Neuroprotective effects of group II metabotropic glutamate receptor agonist DCG-IV on hippocampal neurons in transient forebrain ischemia.
Journal: Neuroscience letters 20090925
Title: gamma-Aminobutyric acid-mediated regulation of the activity-dependent olfactory bulb dopaminergic phenotype.
Journal: Journal of neuroscience research 20090801
Title: Activation of mGlu2/3 metabotropic glutamate receptors negatively regulates the stimulation of inositol phospholipid hydrolysis mediated by 5-hydroxytryptamine2A serotonin receptors in the frontal cortex of living mice.
Journal: Molecular pharmacology 20090801
Title: Antinociceptive synergistic effect of spinal mGluR2/3 antagonist and glial cells inhibitor on peripheral inflammation-induced mechanical hypersensitivity.
Journal: Brain research bulletin 20090529
Title: A transient receptor potential-like channel mediates synaptic transmission in rod bipolar cells.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090513
Title: Epigenetic modulation of mGlu2 receptors by histone deacetylase inhibitors in the treatment of inflammatory pain.
Journal: Molecular pharmacology 20090501
Title: Metabotropic glutamate receptor II in the brains of Parkinsonian patients.
Journal: Journal of neuropathology and experimental neurology 20090401
Title: The slow Ca2+ -dependent K+ -current facilitates synchronization of hyperexcitable pyramidal neurons.
Journal: Brain research 20090203
Title: Group II metabotropic glutamate receptor activation on peripheral nociceptors modulates TRPV1 function.
Journal: Brain research 20090112
Title: Dynamic metabotropic control of intrinsic firing in cerebellar unipolar brush cells.
Journal: Journal of neurophysiology 20081201
Title: GABA(B) receptor activation mediates frequency-dependent plasticity of developing GABAergic synapses.
Journal: Nature neuroscience 20081201
Title: AMPA silencing is a prerequisite for developmental long-term potentiation in the hippocampal CA1 region.
Journal: Journal of neurophysiology 20081101
Title: Repeated exposure to cocaine alters the modulation of mesocorticolimbic glutamate transmission by medial prefrontal cortex Group II metabotropic glutamate receptors.
Journal: Journal of neurochemistry 20081001
Title: Behavioral characterization of the mGlu group II/III receptor antagonist, LY-341495, in animal models of anxiety and depression.
Journal: European journal of pharmacology 20080911
Title: Allosteric potentiators of metabotropic glutamate receptor subtype 1a differentially modulate independent signaling pathways in baby hamster kidney cells.
Journal: Neuropharmacology 20080901
Title: Blockade of group II metabotropic glutamate receptors produces hyper-locomotion in cocaine pre-exposed rats by interactions with dopamine receptors.
Journal: Neuropharmacology 20080901
Title: Conformational change of the transmembrane helices II and IV of metabotropic glutamate receptor involved in G protein activation.
Journal: Journal of neurochemistry 20080701
Title: Group II metabotropic glutamate receptor activation attenuates peripheral sensitization in inflammatory states.
Journal: Neuroscience 20080623
Title: Contribution of cystine-glutamate antiporters to the psychotomimetic effects of phencyclidine.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080601
Title: Face-washing behavior induced by the group I metabotropic glutamate receptor agonist (S)-3,5-DHPG in mice is mediated by mGlu1 receptor.
Journal: European journal of pharmacology 20080531
Title: Involvement of group I mGluRs in LTP induced by strong high frequency stimulation in the dentate gyrus in vitro.
Journal: Neuroscience letters 20080509
Title: Synthesis, in vitro pharmacology, and pharmacokinetic profiles of 2-[1-amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-1-fluorocyclopropanecarboxylic acid and its 6-heptyl ester, a potent mGluR2 antagonist.
Journal: Bioorganic & medicinal chemistry 20080415
Title: A novel assay of Gi/o-linked G protein-coupled receptor coupling to potassium channels provides new insights into the pharmacology of the group III metabotropic glutamate receptors.
Journal: Molecular pharmacology 20080401
Title: Group III mGluR regulation of synaptic transmission at the SC-CA1 synapse is developmentally regulated.
Journal: Neuropharmacology 20080401
Title: Distinct neural mechanisms mediate olfactory memory formation at different timescales.
Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20080301
Title: Basal ganglia group II metabotropic glutamate receptors specific binding in non-human primate model of L-Dopa-induced dyskinesias.
Journal: Neuropharmacology 20080201
Title: Glutamate spillover modulates GABAergic synaptic transmission in the rat midbrain periaqueductal grey via metabotropic glutamate receptors and endocannabinoid signaling.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080123
Title: Differential modulation of ethanol-induced sedation and hypnosis by metabotropic glutamate receptor antagonists in C57BL/6J mice.
Journal: Alcoholism, clinical and experimental research 20080101
Title: Dual GABAergic synaptic response of fast excitation and slow inhibition in the medial habenula of rat epithalamus.
Journal: Journal of neurophysiology 20070901
Title: A selective positive allosteric modulator of metabotropic glutamate receptor subtype 2 blocks a hallucinogenic drug model of psychosis.
Journal: Molecular pharmacology 20070801
Title: In vivo pharmacological characterization of the structurally novel, potent, selective mGlu2/3 receptor agonist LY404039 in animal models of psychiatric disorders.
Journal: Psychopharmacology 20070701
Title: A novel family of potent negative allosteric modulators of group II metabotropic glutamate receptors.
Journal: The Journal of pharmacology and experimental therapeutics 20070701
Title: Group II metabotropic glutamate receptors inhibit glutamate release at thalamocortical synapses in the developing somatosensory cortex.
Journal: Neuroscience 20070525
Title: The effects of the mGluR5 antagonist MPEP and the mGluR2/3 antagonist LY341495 on rats' performance in the 5-choice serial reaction time task.
Journal: Neuropharmacology 20070301
Title: Pharmacological activation of mGlu2/3 metabotropic glutamate receptors protects retinal neurons against anoxic damage in the goldfish Carassius auratus.
Journal: Experimental eye research 20070301
Title: Effects of metabotropic glutamate 2/3 receptor antagonists in the stress-induced hyperthermia test in singly housed mice.
Journal: Psychopharmacology 20070201
Title: Habituation deficits induced by metabotropic glutamate receptors 2/3 receptor blockade in mice: reversal by antipsychotic drugs.
Journal: The Journal of pharmacology and experimental therapeutics 20070201
Title: Endogenous mGluR activity suppresses GABAergic transmission in avian cochlear nucleus magnocellularis neurons.
Journal: Journal of neurophysiology 20070201
Title: Interactive effects of the mGlu5 receptor antagonist MPEP and the mGlu2/3 receptor antagonist LY341495 on nicotine self-administration and reward deficits associated with nicotine withdrawal in rats.
Journal: European journal of pharmacology 20070112
Title: Group III metabotropic glutamate receptor agonists selectively suppress excitatory synaptic currents in the rat prefrontal cortex induced by 5-hydroxytryptamine2A receptor activation.
Journal: The Journal of pharmacology and experimental therapeutics 20070101
Title: Participation of peripheral group I and II metabotropic glutamate receptors in the development or maintenance of IL-1beta-induced mechanical allodynia in the orofacial area of conscious rats.
Journal: Neuroscience letters 20061206
Title: Blockade of group II metabotropic glutamate receptors in the nucleus accumbens produces hyperlocomotion in rats previously exposed to amphetamine.
Journal: Neuropharmacology 20061001
Title: Analgesia mediated by the TRPM8 cold receptor in chronic neuropathic pain.
Journal: Current biology : CB 20060822
Title: Cannabinoid CB1 receptor antagonist AM251 inhibits cocaine-primed relapse in rats: role of glutamate in the nucleus accumbens.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060816
Title: Unique presynaptic and postsynaptic roles of Group II metabotropic glutamate receptors in the modulation of thalamic network activity.
Journal: Neuroscience 20060811
Title: Pharmacological stimulation of group ii metabotropic glutamate receptors reduces cocaine self-administration and cocaine-induced reinstatement of drug seeking in squirrel monkeys.
Journal: The Journal of pharmacology and experimental therapeutics 20060801
Title: Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice.
Journal: The Journal of pharmacology and experimental therapeutics 20060701
Title: Olfactory nerve-evoked, metabotropic glutamate receptor-mediated synaptic responses in rat olfactory bulb mitral cells.
Journal: Journal of neurophysiology 20060401
Title: Differential roles for group 1 mGluR subtypes in induction and expression of chemically induced hippocampal long-term depression.
Journal: Journal of neurophysiology 20060401
Title: Metabotropic glutamate receptor antagonists selectively enhance responses of slowly adapting type I mechanoreceptors.
Journal: Synapse (New York, N.Y.) 20060315
Title: A temporally distinct role for group I and group II metabotropic glutamate receptors in object recognition memory.
Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20060301
Title: Antinociceptive effects and synergistic interaction with morphine of intrathecal metabotropic glutamate receptor 2/3 antagonist in the formalin test of rats.
Journal: Neuroscience letters 20060220
Title: Differential negative coupling of type 3 metabotropic glutamate receptor to cyclic GMP levels in neurons and astrocytes.
Journal: Journal of neurochemistry 20060201
Title: Long-term depression of NMDA receptor-mediated synaptic transmission is dependent on activation of metabotropic glutamate receptors and is altered to long-term potentiation by low intracellular calcium buffering.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060125
Title: Modulation of excitatory synaptic transmission by endogenous glutamate acting on presynaptic group II mGluRs in rat substantia nigra compacta.
Journal: Journal of neuroscience research 20051215
Title: Regulation of IPSP theta rhythm by muscarinic receptors and endocannabinoids in hippocampus.
Journal: Journal of neurophysiology 20051201
Title: Neuroprotective effect of N-acetyl-aspartyl-glutamate in combination with mild hypothermia in the endothelin-1 rat model of focal cerebral ischaemia.
Journal: Journal of neurochemistry 20051201
Title: 2-MPPA, a selective glutamate carboxypeptidase II inhibitor, attenuates morphine tolerance but not dependence in C57/Bl mice.
Journal: Psychopharmacology 20051201
Title: Role of group II metabotropic glutamate receptors 2/3 and group I metabotropic glutamate receptor 5 in developing rat medial vestibular nuclei.
Journal: Neuroreport 20050822
Title: Cystine/glutamate exchange regulates metabotropic glutamate receptor presynaptic inhibition of excitatory transmission and vulnerability to cocaine seeking.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050706
Title: Presynaptic inhibition of corticothalamic feedback by metabotropic glutamate receptors.
Journal: Journal of neurophysiology 20050701
Title: Pharmacological blockade of group II metabotropic glutamate receptors reduces the growth of glioma cells in vivo.
Journal: Neuro-oncology 20050701
Title: Neuropharmacological profiles of antagonists of group II metabotropic glutamate receptors.
Journal: Neuroscience letters 20050422
Title: A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models.
Journal: The Journal of pharmacology and experimental therapeutics 20050401
Title: Anxiolytic-like activity of the mGLU2/3 receptor agonist LY354740 in the elevated plus maze test is disrupted in metabotropic glutamate receptor 2 and 3 knock-out mice.
Journal: Psychopharmacology 20050401
Title: Seizures induced in immature rats by homocysteic acid and the associated brain damage are prevented by group II metabotropic glutamate receptor agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate.
Journal: Experimental neurology 20050401
Title: Developmental switch in synaptic mechanisms of hippocampal metabotropic glutamate receptor-dependent long-term depression.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050316
Title: The metabotropic glutamate (mGLU)2/3 receptor antagonist LY341495 [2S-2-amino-2-(1S,2S-2-carboxycyclopropyl-1-yl)-3-(xanth-9-yl)propanoic acid] stimulates waking and fast electroencephalogram power and blocks the effects of the mGLU2/3 receptor agonist ly379268 [(-)-2-oxa-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate] in rats.
Journal: The Journal of pharmacology and experimental therapeutics 20050201
Title: Metabotropic glutamate receptor 2 modulates excitatory synaptic transmission in the rat globus pallidus.
Journal: Neuropharmacology 20050101
Title: Group II and III mGluRs-mediated presynaptic inhibition of EPSCs recorded from hippocampal interneurons of CA1 stratum lacunosum moleculare.
Journal: Neuropharmacology 20050101
Title: Comparison of c-Fos induction in the brain by the mGlu2/3 receptor antagonist LY341495 and agonist LY354740: evidence for widespread endogenous tone at brain mGlu2/3 receptors in vivo.
Journal: Neuropharmacology 20050101
Title: The preferential mGlu2/3 receptor antagonist, LY341495, reduces the frequency of spike-wave discharges in the WAG/Rij rat model of absence epilepsy.
Journal: Neuropharmacology 20050101
Title: Metabotropic glutamate receptors modulate feedback inhibition in a developmentally regulated manner in rat dentate gyrus.
Journal: The Journal of physiology 20041201
Title: Glutamate transporters and metabotropic receptors regulate excitatory neurotransmission in the medial entorhinal cortex of the rat.
Journal: Brain research 20041119
Title: Glutamate-evoked alterations of glial and neuronal cell morphology in the guinea pig retina.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20041110
Title: Activation of Group II and Group III metabotropic glutamate receptors by endogenous ligand(s) and the modulation of synaptic transmission in the superficial superior colliculus.
Journal: Neuropharmacology 20041101
Title: Distinct properties of carbachol- and DHPG-induced network oscillations in hippocampal slices.
Journal: Neuropharmacology 20040901
Title: Synthesis, in vitro pharmacology, structure-activity relationships, and pharmacokinetics of 3-alkoxy-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives as potent and selective group II metabotropic glutamate receptor antagonists.
Journal: Journal of medicinal chemistry 20040826
Title: Tonic activity of metabotropic glutamate receptors is involved in developmental modification of short-term plasticity in the neocortex.
Journal: Journal of neurophysiology 20040801
Title: Antinociceptive effects of N-acetylaspartylglutamate (NAAG) peptidase inhibitors ZJ-11, ZJ-17 and ZJ-43 in the rat formalin test and in the rat neuropathic pain model.
Journal: The European journal of neuroscience 20040701
Title: Retroinhibition of presynaptic Ca2+ currents by endocannabinoids released via postsynaptic mGluR activation at a calyx synapse.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040630
Title: Modulation of glutamate mobility reveals the mechanism underlying slow-rising AMPAR EPSCs and the diffusion coefficient in the synaptic cleft.
Journal: Neuron 20040610
Title: Depression of GABAergic input to identified hippocampal neurons by group III metabotropic glutamate receptors in the rat.
Journal: The European journal of neuroscience 20040501
Title: Distinct properties of presynaptic group II and III metabotropic glutamate receptor-mediated inhibition of perforant pathway-CA1 EPSCs.
Journal: The European journal of neuroscience 20040501
Title: The selective mGlu2/3 receptor antagonist LY341495 exacerbates behavioral signs of morphine withdrawal and morphine-withdrawal-induced activation of locus coeruleus neurons.
Journal: Neuropharmacology 20040401
Title: Group II metabotropic glutamate receptors inhibit cAMP-dependent protein kinase-mediated enhancemednt of tetrodotoxin-resistant sodium currents in mouse dorsal root ganglion neurons.
Journal: Neuroscience letters 20040311
Title: An NMDAR-independent LTP mediated by group II metabotropic glutamate receptors and p42/44 MAP kinase in the dentate gyrus in vitro.
Journal: Neuropharmacology 20040301
Title: Selective transmission of single photon responses by saturation at the rod-to-rod bipolar synapse.
Journal: Neuron 20040205
Title: Inhibitory effects of group II mGluR-related drugs on memory performance in mice.
Journal: Physiology & behavior 20040201
Title: GCP II (NAALADase) inhibition suppresses mossy fiber-CA3 synaptic neurotransmission by a presynaptic mechanism.
Journal: Journal of neurophysiology 20040101
Title: The mGlu2/3 receptor agonist, LY354740, blocks immobilization-induced increases in noradrenaline and dopamine release in the rat medial prefrontal cortex.
Journal: Journal of neurochemistry 20040101
Title: Cannabinoids decrease corticostriatal synaptic transmission via an effect on glutamate uptake.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20031203
Title: Group II metabotropic glutamate receptor modulation of excitatory transmission in rat subthalamic nucleus.
Journal: The Journal of physiology 20031201
Title: Protective effect of LY379268, a selective group II metabotropic glutamate receptor agonist, on dizocilpine-induced neuropathological changes in rat retrosplenial cortex.
Journal: Brain research 20031128
Title: Prefrontal group II metabotropic glutamate receptor activation decreases performance on a working memory task.
Journal: Annals of the New York Academy of Sciences 20031101
Title: Bidirectional modulation of cystine/glutamate exchanger activity in cultured cortical astrocytes.
Journal: Annals of the New York Academy of Sciences 20031101
Title: Group II metabotropic glutamate receptor antagonists LY341495 and LY366457 increase locomotor activity in mice.
Journal: Neuropharmacology 20031001
Title: Pharmacological characterization and identification of amino acids involved in the positive modulation of metabotropic glutamate receptor subtype 2.
Journal: Molecular pharmacology 20031001
Title: Group II mGlu receptor activation suppresses norepinephrine release in the ventral hippocampus and locomotor responses to acute ketamine challenge.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030901
Title: Protective role of group-II metabotropic glutamate receptors against nigro-striatal degeneration induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.
Journal: Neuropharmacology 20030801
Title: Actions of LY341495 on metabotropic glutamate receptor-mediated responses in the neonatal rat spinal cord.
Journal: British journal of pharmacology 20030501
Title: Reduction of excitatory postsynaptic responses by persistently active metabotropic glutamate receptors in the hippocampus.
Journal: Journal of neurophysiology 20030401
Title: Pharmacological blockade of mGlu2/3 metabotropic glutamate receptors reduces cell proliferation in cultured human glioma cells.
Journal: Journal of neurochemistry 20030301
Title: Baseline glutamate levels affect group I and II mGluRs in layer V pyramidal neurons of rat sensorimotor cortex.
Journal: Journal of neurophysiology 20030301
Title: Synthesis and structure-activity relationship studies of novel 2-diarylethyl substituted (2-carboxycycloprop-1-yl)glycines as high-affinity group II metabotropic glutamate receptor ligands.
Journal: Bioorganic & medicinal chemistry 20030117
Title: Group II metabotropic glutamate receptor modulation of DOI-induced c-fos mRNA and excitatory responses in the cerebral cortex.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030101
Title: Reduced activity of hippocampal group-I metabotropic glutamate receptors in learning-prone rats.
Journal: Neuroscience 20030101
Title: Effect of donepezil on group II mGlu receptor agonist- or antagonist-induced amnesia on passive avoidance in mice.
Journal: Neural plasticity 20030101
Title: Different metabotropic glutamate receptors play opposite roles in synaptic plasticity of the rat medial vestibular nuclei.
Journal: The Journal of physiology 20020915
Title: Modulation of DOI-induced increases in cortical BDNF expression by group II mGlu receptors.
Journal: Pharmacology, biochemistry, and behavior 20020901
Title: The anxiolytic action of mGlu2/3 receptor agonist, LY354740, in the fear-potentiated startle model in rats is mechanistically distinct from diazepam.
Journal: Pharmacology, biochemistry, and behavior 20020901
Title: Peripheral group II metabotropic glutamate receptors (mGluR2/3) regulate prostaglandin E2-mediated sensitization of capsaicin responses and thermal nociception.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020801
Title: Group I metabotropic glutamate receptors (mGluRs) modulate visual responses in the superficial superior colliculus of the rat.
Journal: The Journal of physiology 20020615
Title: Role of p/q-Ca2+ channels in metabotropic glutamate receptor 2/3-dependent presynaptic long-term depression at nucleus accumbens synapses.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020601
Title: Postsynaptic induction and presynaptic expression of group 1 mGluR-dependent LTD in the hippocampal CA1 region.
Journal: Journal of neurophysiology 20020301
Title: Neuroprotective effects of N-acetylaspartylglutamate in a neonatal rat model of hypoxia-ischemia.
Journal: European journal of pharmacology 20020222
Title: Design, synthesis and preliminary evaluation of novel 3'-substituted carboxycyclopropylglycines as antagonists at group 2 metabotropic glutamate receptors.
Journal: Bioorganic & medicinal chemistry letters 20011217
Title: Internalization of ionotropic glutamate receptors in response to mGluR activation.
Journal: Nature neuroscience 20011101
Title: Modulation of primary afferent-mediated neurotransmission and Fos expression by glutamate uptake inhibition in rat spinal neurones in vitro.
Journal: Neuropharmacology 20011001
Title: Differential modulation of the D1-like- and D2-like dopamine receptor-induced locomotor responses by group II metabotropic glutamate receptors in the rat nucleus accumbens.
Journal: Neuropharmacology 20010901
Title: [3H]LY341495 binding to group II metabotropic glutamate receptors in rat brain.
Journal: The Journal of pharmacology and experimental therapeutics 20010801
Title: Changes in rat serum corticosterone after treatment with metabotropic glutamate receptor agonists or antagonists.
Journal: Journal of neuroendocrinology 20010801
Title: Evidence that glutamate acting on presynaptic type-II metabotropic glutamate receptors alone does not fully account for the phenomenon of depolarisation-induced suppression of inhibition in cerebellar Purkinje cells.
Journal: Pflugers Archiv : European journal of physiology 20010601
Title: Activation of group III mGluRs inhibits GABAergic and glutamatergic transmission in the substantia nigra pars reticulata.
Journal: Journal of neurophysiology 20010501
Title: Activity-dependent presynaptic autoinhibition by group II metabotropic glutamate receptors at the perforant path inputs to the dentate gyrus and CA1.
Journal: Neuropharmacology 20010101
Title: Binding of [3H](2S,1'S,2'S)-2-(9-xanthylmethyl)-2-(2'-carboxycyclopropyl) glycine ([3H]LY341495) to cell membranes expressing recombinant human group III metabotropic glutamate receptor subtypes.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20001201
Title: Characterization of [(3)H]-LY354740 binding to rat mGlu2 and mGlu3 receptors expressed in CHO cells using semliki forest virus vectors.
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Title: [3H]-LY341495 as a novel antagonist radioligand for group II metabotropic glutamate (mGlu) receptors: characterization of binding to membranes of mGlu receptor subtype expressing cells.
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Title: Characterization of [3H]-(2S,2'R,3'R)-2-(2',3'-dicarboxy-cyclopropyl)glycine ([3H]-DCG IV) binding to metabotropic mGlu2 receptor-transfected cell membranes.
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Title: LY341495 is a nanomolar potent and selective antagonist of group II metabotropic glutamate receptors.
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Title: Pharmacological analysis of 4-carboxyphenylglycine derivatives: comparison of effects on mGluR1 alpha and mGluR5a subtypes.
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