Home Fluorides 21156-75-2
21156-75-2,MFCD02683983
Catalog No.:AA01X4IC

21156-75-2 | Proline, 4-fluoro-, cis-

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  • Properties
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01X4IC
Chemical Name:
Proline, 4-fluoro-, cis-
CAS Number:
21156-75-2
Molecular Formula:
C5H8FNO2
Molecular Weight:
133.1209
MDL Number:
MFCD02683983
SMILES:
OC(=O)[C@@H]1C[C@@H](CN1)F
Properties
Computed Properties
 
Complexity:
128  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
-2.3  

Literature

Title: Rational design of protein stability: effect of (2S,4R)-4-fluoroproline on the stability and folding pathway of ubiquitin.

Journal: PloS one 20110101

Title: Thermodynamic consequences of incorporating 4-substituted proline derivatives into a small helical protein.

Journal: Biochemistry 20100518

Title: Stereoelectronic effects on the transition barrier of polyproline conformational interconversion.

Journal: Protein science : a publication of the Protein Society 20090901

Title: Direct and continuous assay for prolyl 4-hydroxylase.

Journal: Analytical biochemistry 20090315

Title: Conformational preferences of substrates for human prolyl 4-hydroxylase.

Journal: Biochemistry 20080909

Title: Stereoelectronic effects on polyproline conformation.

Journal: Protein science : a publication of the Protein Society 20060101

Title: A stereoelectronic effect on turn formation due to proline substitution in elastin-mimetic polypeptides.

Journal: Journal of the American Chemical Society 20051228

Title: Stereoelectronic and steric effects in the collagen triple helix: toward a code for strand association.

Journal: Journal of the American Chemical Society 20051116

Title: Substituted 2-azabicyclo[2.1.1]hexanes as constrained proline analogues: implications for collagen stability.

Journal: The Journal of organic chemistry 20041210

Title: Stereoelectronic effects on collagen stability: the dichotomy of 4-fluoroproline diastereomers.

Journal: Journal of the American Chemical Society 20030806

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SDS
Tags:21156-75-2 Molecular Formula|21156-75-2 MDL|21156-75-2 SMILES|21156-75-2 Proline, 4-fluoro-, cis-