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217963-18-3,MFCD30489751
Catalog No.:AA00BF53

217963-18-3 | SCH00013

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
1 week  
$273.00   $191.00
- +
5mg
98%
1 week  
$717.00   $502.00
- +
10mg
98%
1 week  
$1,035.00   $724.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00BF53
Chemical Name:
SCH00013
CAS Number:
217963-18-3
Molecular Formula:
C18H20N4O2
Molecular Weight:
324.3770
MDL Number:
MFCD30489751
SMILES:
N#Cc1ccc(cc1)C(CN1CCC(=CC1)C1=NNC(=O)CC1)O
Properties
Computed Properties
 
Complexity:
581  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
1  
XLogP3:
0.2  

Literature

Title: Cardiac Ca2+ signaling and Ca2+ sensitizers.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20081201

Title: SCH00013, a novel Ca(2+) sensitizer with positive inotropic and no chronotropic action in heart failure.

Journal: Journal of pharmacological sciences 20050101

Title: Investigation on SCH00013, a novel cardiotonic agent with Ca++ sensitizing action. 4th communication: influence on experimentally induced ventricular arrhythmia in dogs.

Journal: Arzneimittel-Forschung 19990501

Title: Sugawara H et al. A novel cardiotonic agent SCH00013 acts as a Ca++ sensitizer with no chronotropic activity in mammalian cardiac muscle.J Pharmacol Exp Ther. 1998 Oct;287(1):214-22.

Title: Tadano N et al. SCH00013, a novel Ca(2+) sensitizer with positive inotropic and no chronotropic action in heart failure. J Pharmacol Sci. 2005 Jan;97(1):53-60.

Title: Endoh M et al. Pharmacology of SCH00013: a novel Ca2+ sensitizer. Cardiovasc Drug Rev. 2001 Winter;19(4):345-66.

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