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221697-09-2,MFCD04112988
Catalog No.:AA01EO9I

221697-09-2 | Y1 receptor antagonist 1

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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01EO9I
Chemical Name:
Y1 receptor antagonist 1
CAS Number:
221697-09-2
Molecular Formula:
C28H33N5O3
Molecular Weight:
487.5933
MDL Number:
MFCD04112988
SMILES:
NC(=N)NCCC[C@H](C(=O)N[C@@H](c1ccc(cc1)O)C)NC(=O)C(c1ccccc1)c1ccccc1
Properties
Computed Properties
 
Complexity:
688  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
36  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
11  
XLogP3:
2.9  

Literature

Title: Attenuation of acute experimental colitis by preventing NPY Y1 receptor signaling.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20050301

Title: Receptor subtypes Y1 and Y5 mediate neuropeptide Y induced feeding in the guinea-pig.

Journal: British journal of pharmacology 20020401

Title: Existence of both neuropeptide Y, Y1 and Y2 receptors in pig spleen: evidence using subtype-selective antagonists in vivo.

Journal: Life sciences 20010914

Title: Role of neuropeptide Y in renal sympathetic vasoconstriction: studies in normal and congestive heart failure rats.

Journal: The Journal of laboratory and clinical medicine 20010801

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