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Title: Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis.
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Title: The pharmacokinetic evaluation of mirabegron as an overactive bladder therapy option.
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Title: Single dose pharmacokinetics and absolute bioavailability of mirabegron, a β₃-adrenoceptor agonist for treatment of overactive bladder.
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Title: Identification of human cytochrome P450 isoforms and esterases involved in the metabolism of mirabegron, a potent and selective β3-adrenoceptor agonist.
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Title: Pharmacokinetic properties of mirabegron, a β3-adrenoceptor agonist: results from two phase I, randomized, multiple-dose studies in healthy young and elderly men and women.
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Title: An aryloxypropanolamine hβ3-adrenoceptor agonist as bladder smooth muscle relaxant.
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Title: Overactive bladder, under scrutiny, gets a new treatment.
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Title: Modulation of non-voiding activity by the muscarinergic antagonist tolterodine and the β(3)-adrenoceptor agonist mirabegron in conscious rats with partial outflow obstruction.
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Title: Modulation of non-voiding activity by the muscarinergic antagonist tolterodine and the β(3)-adrenoceptor agonist mirabegron in conscious rats with partial outflow obstruction.
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Title: [Pharmacological and clinical profile of mirabegron (Betanis(®)): a new therapeutic agent for overactive bladder].
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Title: Treatment of overactive bladder symptoms beyond antimuscarinics: current and future therapies.
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Title: Stress urinary incontinence and overactive bladder syndrome: current options and new targets for management.
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Title: Absorption, metabolism and excretion of [(14)C]mirabegron (YM178), a potent and selective β(3)-adrenoceptor agonist, after oral administration to healthy male volunteers.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20120401
Title: Development and validation of LC-MS/MS methods for the determination of mirabegron and its metabolites in human plasma and their application to a clinical pharmacokinetic study.
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Title: Mirabegron for the treatment of overactive bladder.
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Title: Mirabegron: a safety review.
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Title: Beta3-adrenoceptor agonists: possible role in the treatment of overactive bladder.
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Title: Mirabegron, a β₃-adrenoceptor agonist for the potential treatment of urinary frequency, urinary incontinence or urgency associated with overactive bladder.
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Title: Effect of pre-contraction on β-adrenoceptor-mediated relaxation of rat urinary bladder.
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Title: Effect of (R)-2-(2-aminothiazol-4-yl)-4'-{2-[(2-hydroxy-2-phenylethyl)amino]ethyl} acetanilide (YM178), a novel selective beta3-adrenoceptor agonist, on bladder function.
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Title: Relaxation of human detrusor muscle by selective beta-2 and beta-3 agonists and endogenous catecholamines.
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Title: A quantitative analysis of mRNA expression of alpha 1 and beta-adrenoceptor subtypes and their functional roles in human normal and obstructed bladders.
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Title: Beta3-adrenoceptors in human detrusor muscle.
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