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23633-07-0,MFCD01674282
Catalog No.:AA00I4HX

23633-07-0 | 2-Amino-3-(4-chlorophenyl)propanoic acid hydrochloride

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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I4HX
Chemical Name:
2-Amino-3-(4-chlorophenyl)propanoic acid hydrochloride
CAS Number:
23633-07-0
Molecular Formula:
C9H11Cl2NO2
Molecular Weight:
236.0951
MDL Number:
MFCD01674282
SMILES:
NC(C(=O)O)Cc1ccc(cc1)Cl.Cl
Properties
Computed Properties
 
Complexity:
179  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
1  

Literature

Title: Serotonin passes through myoendothelial gap junctions to promote pulmonary arterial smooth muscle cell differentiation.

Journal: American journal of physiology. Lung cellular and molecular physiology 20121101

Title: Ferulic acid potentiates pentobarbital-induced sleep via the serotonergic system.

Journal: Neuroscience letters 20120913

Title: Prefrontal cortical anandamide signaling coordinates coping responses to stress through a serotonergic pathway.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20120901

Title: Inhibitory effect of ramosetron on corticotropin releasing factor- and soybean oil-induced delays in gastric emptying in rats.

Journal: Journal of gastroenterology and hepatology 20120901

Title: Dual role of serotonin in the pathogenesis of indomethacin-induced small intestinal ulceration: pro-ulcerogenic action via 5-HT3 receptors and anti-ulcerogenic action via 5-HT4 receptors.

Journal: Pharmacological research 20120901

Title: Impaired reward learning and intact motivation after serotonin depletion in rats.

Journal: Behavioural brain research 20120801

Title: A pharmacological evidence of positive association between mouse intermale aggression and brain serotonin metabolism.

Journal: Behavioural brain research 20120715

Title: A possible participation of transient receptor potential vanilloid type 1 channels in the antidepressant effect of fluoxetine.

Journal: European journal of pharmacology 20120615

Title: Effects of prenatal stress and monoaminergic perturbations on the expression of serotonin 5-HT₄ and adrenergic β₂ receptors in the embryonic mouse telencephalon.

Journal: Brain research 20120612

Title: On the presence of serotonin in mammalian cardiomyocytes.

Journal: Molecular and cellular biochemistry 20120601

Title: AMPA glutamate receptors mediate the antidepressant-like effects of N-acetylcysteine in the mouse tail suspension test.

Journal: Behavioural pharmacology 20120401

Title: Uliginosin B, a phloroglucinol derivative from Hypericum polyanthemum: a promising new molecular pattern for the development of antidepressant drugs.

Journal: Behavioural brain research 20120301

Title: Effects of noradrenaline and serotonin depletions on the neuronal activity of globus pallidus and substantia nigra pars reticulata in experimental parkinsonism.

Journal: Neuroscience 20120127

Title: Pharmacological mechanisms of antidepressant-like effect of tipepidine in the forced swimming test.

Journal: Behavioural brain research 20120115

Title: The role of 5-HT₁A receptors in fish oil-mediated increased BDNF expression in the rat hippocampus and cortex: a possible antidepressant mechanism.

Journal: Neuropharmacology 20120101

Title: Adverse effects of serotonin depletion in developing zebrafish.

Journal: Neurotoxicology and teratology 20120101

Title: Induction of glucose intolerance by acute administration of rimonabant.

Journal: Pharmacology 20120101

Title: [The role of serotonin in the immune system development and functioning during ontogenesis].

Journal: Izvestiia Akademii nauk. Seriia biologicheskaia 20120101

Title: Antidepressant-like activity of ellagic acid in unstressed and acute immobilization-induced stressed mice.

Journal: Pharmacological reports : PR 20120101

Title: P-chlorophenylalanine increases glutamate receptor 1 transcription in rat amygdala.

Journal: Neuroreport 20111026

Title: p-Hydroxyamphetamine causes prepulse inhibition disruption in mice: contribution of serotonin neurotransmission.

Journal: Behavioural brain research 20111010

Title: Cytochrome P450 is regulated by noradrenergic and serotonergic systems.

Journal: Pharmacological research 20111001

Title: Antidepressant-like effects of mineralocorticoid but not glucocorticoid antagonists in the lateral septum: interactions with the serotonergic system.

Journal: Behavioural brain research 20110930

Title: Taltirelin, a thyrotropin-releasing hormone analog, alleviates mechanical allodynia through activation of descending monoaminergic neurons in persistent inflammatory pain.

Journal: Brain research 20110926

Title: A test to determine the nature and presence of the memory effect columns packed with the amylose tris(3,5-dimethylphenylcarbamate) stationary phase.

Journal: Journal of chromatography. A 20110916

Title: Involvement of GABAergic non-benzodiazepine sites in the anxiolytic-like and sedative effects of the flavonoid baicalein in mice.

Journal: Behavioural brain research 20110801

Title: Combined effect of early life stress and acute stress on colonic sensory and motor responses through serotonin pathways: differences between proximal and distal colon in rats.

Journal: Stress (Amsterdam, Netherlands) 20110701

Title: Evaluation of object-based attention in mice.

Journal: Behavioural brain research 20110620

Title: Antidepressant-like effect of carvacrol (5-Isopropyl-2-methylphenol) in mice: involvement of dopaminergic system.

Journal: Fundamental & clinical pharmacology 20110601

Title: Involvement of serotonergic system in the antidepressant-like effect of piperine.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20110601

Title: An approach for serotonin depletion in pigs: effects on serotonin receptor binding.

Journal: Synapse (New York, N.Y.) 20110201

Title: Administration of serotonin inhibitor p-Chlorophenylalanine induces pessimistic-like judgement bias in sheep.

Journal: Psychoneuroendocrinology 20110201

Title: Effects of serotonergic drugs on locomotor activity and vigilance states in ring doves.

Journal: Behavioural brain research 20110101

Title: 5-hydroxyindolacetic acid (5-HIAA), a main metabolite of serotonin, is responsible for complete Freund's adjuvant-induced thermal hyperalgesia in mice.

Journal: Molecular pain 20110101

Title: High-intensity extended swimming exercise reduces pain-related behavior in mice: involvement of endogenous opioids and the serotonergic system.

Journal: The journal of pain : official journal of the American Pain Society 20101201

Title: Visceral hypersensitivity induced by activation of transient receptor potential vanilloid type 1 is mediated through the serotonin pathway in rat colon.

Journal: European journal of pharmacology 20101125

Title: The role of endogenous serotonin in methamphetamine-induced neurotoxicity to dopamine nerve endings of the striatum.

Journal: Journal of neurochemistry 20101101

Title: Involvement of monoaminergic system in the antidepressant-like effect of the flavonoid naringenin in mice.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20101001

Title: The antidepressant-like action of metabotropic glutamate 7 receptor agonist N,N'-bis(diphenylmethyl)-1,2-ethanediamine (AMN082) is serotonin-dependent.

Journal: The Journal of pharmacology and experimental therapeutics 20100901

Title: Strain-dependent serotonin neuron feedback control: role of serotonin 2C receptors.

Journal: Journal of neurochemistry 20100901

Title: Monoamine oxidases regulate telencephalic neural progenitors in late embryonic and early postnatal development.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100811

Title: Pharmacological or genetic inactivation of the serotonin transporter improves reversal learning in mice.

Journal: Cerebral cortex (New York, N.Y. : 1991) 20100801

Title: Effects of fluoxetine and PCPA on isolation-induced morphine self-administration and startle reactivity.

Journal: Pharmacology, biochemistry, and behavior 20100701

Title: Antidepressant-like effect of trans-resveratrol: Involvement of serotonin and noradrenaline system.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20100601

Title: Sex and regional differences in decrease of serotonin-immunoreactive cells by parachlorophenylalanine in rat raphe nuclei.

Journal: Neuroscience research 20100501

Title: Both synthesis and reuptake are critical for replenishing the releasable serotonin pool in Drosophila.

Journal: Journal of neurochemistry 20100401

Title: Antidepressant-like effect of the methanolic extract from Bupleurum falcatum in the tail suspension test.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20100317

Title: A model of symptomatic infantile spasms syndrome.

Journal: Neurobiology of disease 20100301

Title: [Effect of serotonin on the formation of neurons producing gonadotropin-releasing hormone in Wistar rats].

Journal: Ontogenez 20100101

Title: Evaluation of anti-compulsive effect of methanolic extract of Benincasa hispida Cogn. fruit in mice.

Journal: Acta poloniae pharmaceutica 20100101

Title: Neonatal DSP-4 treatment impairs 5-HT(1B) receptor reactivity in adult rats. Behavioral and biochemical studies.

Journal: Pharmacological reports : PR 20100101

Title: Serotonin has a key role in pathogenesis of experimental colitis.

Journal: Gastroenterology 20091101

Title: TRPA1 agonists delay gastric emptying in rats through serotonergic pathways.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20091001

Title: Serotonin, social status and sex change in the bluebanded goby Lythrypnus dalli.

Journal: Physiology & behavior 20090622

Title: Imaging elevated brain arachidonic acid signaling in unanesthetized serotonin transporter (5-HTT)-deficient mice.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090601

Title: The brain 5-HT4 receptor binding is down-regulated in the Flinders Sensitive Line depression model and in response to paroxetine administration.

Journal: Journal of neurochemistry 20090601

Title: Association of changes in norepinephrine and serotonin transporter expression with the long-term behavioral effects of antidepressant drugs.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090501

Title: Neural network detects the effects of p-CPA pre-treatment on brain electrophysiology in a rat model of focal brain injury.

Journal: Journal of clinical monitoring and computing 20090401

Title: The involvement of serotonergic system in the antidepressant effect of zinc in the forced swim test.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20090317

Title: Evidence that increased 5-HT release evokes region-specific effects on blood-oxygenation level-dependent functional magnetic resonance imaging responses in the rat brain.

Journal: Neuroscience 20090317

Title: Chronic intermittent cold stress and serotonin depletion induce deficits of reversal learning in an attentional set-shifting test in rats.

Journal: Psychopharmacology 20090101

Title: [Brain is a source of blood serotonin in rats during perinatal development].

Journal: Ontogenez 20090101

Title: Potentiating effect of diltiazem on pentobarbital-induced hypnosis is augmented by serotonergic system: the TMN and VLPO as key elements in the pathway.

Journal: Neuropharmacology 20090101

Title: Serotonin-depleted rats are capable of learning in active place avoidance, a spatial task requiring cognitive coordination.

Journal: Physiological research 20090101

Title: Effect of serotonin deficiency on the immune system development in the rat.

Journal: Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20090101

Title: [Comparison of the effects of selank and tuftsin on the metabolism of serotonin in the brain of rats pretreated with PCPA].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20090101

Title: Diurnal variation in phagocytic activity of splenic phagocytes in freshwater teleost Channa punctatus: melatonin and its signaling mechanism.

Journal: The Journal of endocrinology 20081201

Title: Serotonin metabolism is dysregulated in cholangiocarcinoma, which has implications for tumor growth.

Journal: Cancer research 20081115

Title: Conditional mouse mutants highlight mechanisms of corticotropin-releasing hormone effects on stress-coping behavior.

Journal: Molecular psychiatry 20081101

Title: Maternal para-chlorophenylalanine exposure modifies central monoamines and behaviors in the adult offspring.

Journal: Brain research 20081009

Title: Anticataleptic 8-OH-DPAT preferentially counteracts with haloperidol-induced Fos expression in the dorsolateral striatum and the core region of the nucleus accumbens.

Journal: Neuropharmacology 20081001

Title: Desipramine potentiation of the acute depressant effects of ethanol: modulation by alpha2-adrenoreceptors and stress.

Journal: Neuropharmacology 20081001

Title: The effects of an anabolic androgenic steroid and low serotonin on social and non-social behaviors in male rats.

Journal: Brain research 20080926

Title: Serotonin hyperinnervation abolishes seizure susceptibility in Otx2 conditional mutant mice.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080910

Title: Spinosin, a C-glycoside flavonoid from semen Zizhiphi Spinozae, potentiated pentobarbital-induced sleep via the serotonergic system.

Journal: Pharmacology, biochemistry, and behavior 20080901

Title: Evaluation of the antibradykinetic actions of 5-HT1A agonists using the mouse pole test.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20080701

Title: Antidepressant-like effect of rutin isolated from the ethanolic extract from Schinus molle L. in mice: evidence for the involvement of the serotonergic and noradrenergic systems.

Journal: European journal of pharmacology 20080610

Title: Role for serotonin in the antidepressant-like effect of a flavonoid extract of Xiaobuxin-Tang.

Journal: Pharmacology, biochemistry, and behavior 20080601

Title: Serotonergic mediation of the antidepressant-like effect of the green leaves odor in mice.

Journal: Neuroscience letters 20080509

Title: Combined but not individual administration of beta-adrenergic and serotonergic antagonists impairs water maze acquisition in the rat.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080501

Title: The effect of corticotropin-releasing factor on prepulse inhibition is independent of serotonin in Brown Norway and Wistar-Kyoto rats.

Journal: Pharmacology, biochemistry, and behavior 20080501

Title: The immobility produced by intermittent swim stress is not mediated by serotonin.

Journal: Pharmacology, biochemistry, and behavior 20080501

Title: Gastric relaxation induced by hyperglycemia is mediated by vagal afferent pathways in the rat.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20080501

Title: Evaluation of serotonin as a feedback inhibitor of lactation in the bovine.

Journal: Journal of dairy science 20080501

Title: [5-HT1A/1B receptors, alpha2-adrenoceptors and the post-receptor adenylate cyclase activation in the mice brain are involved in the antidepressant-like action of agmatine].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20080501

Title: Antidepressant-like effect of agmatine is not mediated by serotonin.

Journal: Behavioural brain research 20080409

Title: Relationship between serotonin and the immune system in a teleost model.

Journal: Brain, behavior, and immunity 20080201

Title: Folic acid administration produces an antidepressant-like effect in mice: evidence for the involvement of the serotonergic and noradrenergic systems.

Journal: Neuropharmacology 20080201

Title: Antidepressive-like effects of electroacupuncture in rats.

Journal: Physiology & behavior 20080128

Title: [Effect of serotonin deficit at different stages of prenatal ontogenesis on behavior of adult male and female rats].

Journal: Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20080101

Title: An immunohistochemical study of the antinociceptive effect of calcitonin in ovariectomized rats.

Journal: BMC musculoskeletal disorders 20080101

Title: Effect of two behavioral tests on corticosterone level in plasma of mice lacking the noradrenaline transporter.

Journal: Pharmacological reports : PR 20080101

Title: Tryptophan hydroxylase 1 knockout and tryptophan hydroxylase 2 polymorphism: effects on hypoxic pulmonary hypertension in mice.

Journal: American journal of physiology. Lung cellular and molecular physiology 20071001

Title: Behavioral alteration in the adult rats prenatally exposed to para-chlorophenylalanine.

Journal: Brain research 20070912

Title: Effect of tandospirone on sleep latency in rats placed on a grid suspended over water.

Journal: Journal of pharmacological sciences 20070901

Title: Brain serotonin depletion impairs short-term memory, but not long-term memory in rats.

Journal: Physiology & behavior 20070815

Title: Monoaminergic agents modulate antidepressant-like effect caused by diphenyl diselenide in rats.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20070815

Title: Water maze impairments after combined depletion of somatostatin and serotonin in the rat.

Journal: Behavioural brain research 20070719

Title: cAMP response element-binding protein deficiency allows for increased neurogenesis and a rapid onset of antidepressant response.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070718

Title: Serotonin mediates rapid changes of striatal glucose and lactate metabolism after systemic 3,4-methylenedioxymethamphetamine (MDMA, 'Ecstasy') administration in awake rats.

Journal: Neurochemistry international 20070701

Title: Evaluation of the antidepressant-like activity of Convolvulus pluricaulis choisy in the mouse forced swim and tail suspension tests.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20070701

Title: Embryonic depletion of serotonin affects cortical development.

Journal: The European journal of neuroscience 20070701

Title: Influence of PCPA and MDMA (ecstasy) on physiology, development and behavior in Drosophila melanogaster.

Journal: The European journal of neuroscience 20070701

Title: Depletion of serotonin and catecholamines block the acute behavioral response to different classes of antidepressant drugs in the mouse tail suspension test.

Journal: Psychopharmacology 20070601

Title: LHRH antagonist attenuates the effect of fluoxetine on marble-burying behavior in mice.

Journal: European journal of pharmacology 20070601

Title: [Influence of para-chlorophenylanine on rat's aggressive behavior and neurochemical correlates].

Journal: Georgian medical news 20070501

Title: Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor.

Journal: Blood 20070415

Title: Anxiolytic effect of serotonin depletion in the novelty-induced hypophagia test.

Journal: Psychopharmacology 20070301

Title: Serotonin is involved in the regulation of histogenetic processes in rat embryonic neocortex.

Journal: Bulletin of experimental biology and medicine 20070301

Title: Analysis of dencichine in Panax notoginseng by gas chromatography-mass spectrometry with ethyl chloroformate derivatization.

Journal: Journal of pharmaceutical and biomedical analysis 20070219

Title: Behavioral effects of pubertal anabolic androgenic steroid exposure in male rats with low serotonin.

Journal: Brain research 20070209

Title: The synthetic TRH analogue taltirelin exerts modality-specific antinociceptive effects via distinct descending monoaminergic systems.

Journal: British journal of pharmacology 20070201

Title: Serotonin stimulates [Ca2+]i elevation in ciliary ectodermal cells of echinoplutei through a serotonin receptor cell network in the blastocoel.

Journal: The Journal of experimental biology 20070201

Title: Serotonin concentration, synthesis, cell origin, and targets in the rat caput epididymis during sexual maturation and variations associated with adult mating status: morphological and biochemical studies.

Journal: Journal of andrology 20070101

Title: Serotonin decreases aggression via 5-HT1A receptors in the fighting fish Betta splendens.

Journal: Pharmacology, biochemistry, and behavior 20070101

Title: [Behavior of female and male mice submitted to action of p-chlorophenylalanine in prenatal ontogenesis].

Journal: Zhurnal evoliutsionnoi biokhimii i fiziologii 20070101

Title: Depletion of serotonin synthesis with p-CPA pretreatment alters EEG in urethane anesthetized rats under whole body hyperthermia.

Journal: Iranian biomedical journal 20070101

Title: [Study of effect of serotonin on histogenesis of rat embryonal neocortex at model of ectopic neurotransplantation].

Journal: Zhurnal evoliutsionnoi biokhimii i fiziologii 20070101

Title: Phenytoin normalizes exaggerated fear behavior in p-chlorophenylalanine (PCPA)-treated rats.

Journal: Epilepsy & behavior : E&B 20061201

Title: Potentiating effects of L-type Ca(2+) channel blockers on pentobarbital-induced hypnosis are influenced by serotonergic system.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20061001

Title: Study of mitotic activity and degeneration of cells in the dorsolateral wall of the anterior cerebral vesicle in rat embryos on the model of ectopic neurotransplantation.

Journal: Bulletin of experimental biology and medicine 20060801

Title: Anticonvulsant effect of the selective 5-HT1B receptor agonist CP 94253 in mice.

Journal: European journal of pharmacology 20060710

Title: In vivo effect of tramadol on locus coeruleus neurons is mediated by alpha2-adrenoceptors and modulated by serotonin.

Journal: Neuropharmacology 20060701

Title: Formation of the neocortex in mice developing in conditions of prenatal serotonin deficiency.

Journal: Neuroscience and behavioral physiology 20060601

Title: Effects of constant lightness, darkness and parachlorophenylalanine treatment on tail regeneration in the lizard Ophisops elegans macrodactylus: macroscopic, biochemical and histological changes.

Journal: Anatomia, histologia, embryologia 20060601

Title: Formation of the astroglia in the mouse neocortex after temporary prenatal blockade of serotonin synthesis.

Journal: Neuroscience and behavioral physiology 20060301

Title: Selective serotonin depletion does not regulate hippocampal neurogenesis in the adult rat brain: differential effects of p-chlorophenylalanine and 5,7-dihydroxytryptamine.

Journal: Brain research 20060223

Title: Serotonin depletion results in a decrease of the neuronal activation caused by rivastigmine in the rat hippocampus.

Journal: Brain research 20060216

Title: Serotonin depletion attenuates AY-9944-mediated atypical absence seizures.

Journal: Epilepsia 20060201

Title: P-CPA pretreatment reverses the changes in sleep and behavior following acute immobilization stress rats.

Journal: The journal of physiological sciences : JPS 20060201

Title: Specificity and efficacy of noradrenaline, serotonin depletion in discrete brain areas of Swiss mice by neurotoxins.

Journal: Journal of neuroscience methods 20060115

Title: Antidepressant-like activity of n-hexane extract of nutmeg (Myristica fragrans) seeds in mice.

Journal: Journal of medicinal food 20060101

Title: Role of serotonin in cerebral oxidative stress in rats.

Journal: Acta neurobiologiae experimentalis 20060101

Title: Effects of central and peripheral depletion of serotonergic system on carrageenan-induced paw oedema.

Journal: International immunopharmacology 20051101

Title: Serotonin synthesis inhibition reveals distinct mechanisms of action for MDMA and its enantiomers in the mouse.

Journal: Psychopharmacology 20050901

Title: Parachlorophenylalanine exacerbates oxidative stress induced by gentamicin in rats.

Journal: Basic & clinical pharmacology & toxicology 20050901

Title: Effect of 5-HT depletion on cardiovascular vagal reflex sensitivity in awake and anesthetized rats.

Journal: Brain research 20050823

Title: Effects of selegiline alone or with donepezil on memory impairment in rats.

Journal: European journal of pharmacology 20050822

Title: Role of serotonin (5-HT) in the antidepressant-like properties of neuropeptide Y (NPY) in the mouse forced swim test.

Journal: Peptides 20050801

Title: Anxiolytic-like effect of milnacipran in the four-plate test in mice: mechanism of action.

Journal: Pharmacology, biochemistry, and behavior 20050701

Title: The role of 5-HT in the impairment of thermoregulation observed in rats administered MDMA ('ecstasy') when housed at high ambient temperature.

Journal: Psychopharmacology 20050601

Title: Sex differences in the regulation of serotonergic transmission and behavior in 5-HT receptor knockout mice.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050601

Title: Antidepressant-like effect of the selective 5-HT1B receptor agonist CP 94253: a possible mechanism of action.

Journal: European journal of pharmacology 20050523

Title: Differential involvement of serotonin and dopamine systems in cost-benefit decisions about delay or effort.

Journal: Psychopharmacology 20050501

Title: Effects of serotonin and serotonergic agonists and antagonists on the production of tumor necrosis factor alpha and interleukin-6.

Journal: Psychiatry research 20050430

Title: Involvement of serotonin in the hypoglycemic response to 2 Hz electroacupuncture of zusanli acupoint (ST36) in rats.

Journal: Neuroscience letters 20050429

Title: A reassessment of the role of serotonergic system in the control of feeding behavior.

Journal: Anais da Academia Brasileira de Ciencias 20050301

Title: Analysis of serotonin in brain microdialysates using capillary electrophoresis and native laser-induced fluorescence detection.

Journal: Electrophoresis 20050301

Title: Serotonin refines the locomotor-related alternations in the in vitro neonatal rat spinal cord.

Journal: The European journal of neuroscience 20050301

Title: Serotonin modulates the suppressive effects of corticosterone on proliferating progenitor cells in the dentate gyrus of the hippocampus in the adult rat.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050201

Title: Long-lasting effects of serotonin deficiency on differentiating peptidergic neurons in the rat suprachiasmatic nucleus.

Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20050201

Title: Dissociating barrel development and lesion-induced plasticity in the mouse somatosensory cortex.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050119

Title: GABAB receptor antagonist-mediated antidepressant-like behavior is serotonin-dependent.

Journal: The Journal of pharmacology and experimental therapeutics 20050101

Title: [Astroglia formation in the neocortex of mice after temporary prenatal serotonin depletion].

Journal: Morfologiia (Saint Petersburg, Russia) 20050101

Title: [Neocortex formation in mice developing after prenatal serotonin depletion].

Journal: Morfologiia (Saint Petersburg, Russia) 20050101

Title: Tetrandrine, a bisbenzylisoquinoline alkaloid from Chinese herb Radix, augmented the hypnotic effect of pentobarbital through serotonergic system.

Journal: European journal of pharmacology 20041215

Title: 5-HT1A receptors are differentially involved in the anxiolytic- and antidepressant-like effects of 8-OH-DPAT and fluoxetine in the rat.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20041201

Title: Serotonin and stress: protective or malevolent actions in the biobehavioral response to repeated trauma?

Journal: Annals of the New York Academy of Sciences 20041201

Title: Evidence for serotonin receptor subtypes involvement in agmatine antidepressant like-effect in the mouse forced swimming test.

Journal: Brain research 20041015

Title: Elevated serotonin is involved in hyperactivity but not in the paradoxical effect of amphetamine in mice neonatally lesioned with 6-hydroxydopamine.

Journal: Journal of neuroscience research 20041015

Title: Serotonin involvement in the electroacupuncture- and moxibustion-induced gastric emptying in rats.

Journal: Physiology & behavior 20041015

Title: 5-HT-mediated inhibition of cardiovagal baroreceptor reflex response during defense reaction in the rat.

Journal: American journal of physiology. Heart and circulatory physiology 20041001

Title: Loss of flight and associated neuronal rhythmicity in inositol 1,4,5-trisphosphate receptor mutants of Drosophila.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040908

Title: Effects of autacoid inhibitors and of an antagonist on malaria infection in mice.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20040801

Title: Increased CRE-binding activity and tryptophan hydroxylase mRNA expression induced by 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') in the rat frontal cortex but not in the hippocampus.

Journal: Brain research. Molecular brain research 20040726

Title: Immediate plasticity in the motor pathways after spinal cord hemisection: implications for transcranial magnetic motor-evoked potentials.

Journal: Experimental neurology 20040601

Title: NMDA receptor subunit and CaMKII changes in rat hippocampus induced by acute MDMA treatment: a mechanism for learning impairment.

Journal: Psychopharmacology 20040501

Title: Evidence of melatonin synthesis by human lymphocytes and its physiological significance: possible role as intracrine, autocrine, and/or paracrine substance.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040301

Title: Brain serotonin depletion enhances the sodium appetite induced by sodium depletion or beta-adrenergic stimulation.

Journal: Anais da Academia Brasileira de Ciencias 20040301

Title: Serotonin regulates mammary gland development via an autocrine-paracrine loop.

Journal: Developmental cell 20040201

Title: Endogenous 5-HT inhibits firing activity of hippocampal CA1 pyramidal neurons during conditioned fear stress-induced freezing behavior through stimulating 5-HT1A receptors.

Journal: Hippocampus 20040101

Title: Serotonergic and dopaminergic influence of the duration of embryogenesis and intracapsular locomotion of Lymnaea stagnalis L.

Journal: Acta biologica Hungarica 20040101

Title: 5-HT1A and beta-adrenergic receptors regulate proliferation of rat blood lymphocytes.

Journal: Neuroimmunomodulation 20040101

Title: Serotonin synthesis inhibition in olivo-cerebellar system attenuates harmaline-induced tremor in Swiss albino mice.

Journal: Behavioural brain research 20031017

Title: Elimination of serotonergic cells induces a marked increase in generation of dopaminergic neurons from mesencephalic precursors.

Journal: The European journal of neuroscience 20031001

Title: Orienting and defensive behaviors elicited by superior colliculus stimulation in rats: effects of 5-HT depletion, uptake inhibition, and direct midbrain or frontal cortex application.

Journal: Behavioural brain research 20030915

Title: The effects of serotonin on the differentiation of neurons producing vasoactive intestinal polypeptide in the suprachiasmatic nucleus of the rat.

Journal: Neuroscience and behavioral physiology 20030901

Title: Effect of the inhibition of serotonin biosynthesis on the antinociception induced by nonsteroidal anti-inflammatory drugs.

Journal: Brain research bulletin 20030830

Title: Is the Ecstasy-induced ipsilateral rotation in 6-hydroxydopamine unilaterally lesioned rats dopamine independent?

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20030701

Title: Influence of serotonin on the development and migration of gonadotropin-releasing hormone neurones in rat foetuses.

Journal: Journal of neuroendocrinology 20030601

Title: Evidence for a monoamine mediated, opioid-independent, antihyperalgesic effect of venlafaxine, a non-tricyclic antidepressant, in a neurogenic pain model in rats.

Journal: Pain 20030601

Title: Serotonin depletion enhances the intracerebroventricularly administered MK-801-induced plasma interleukin-6 levels in mice.

Journal: Biological & pharmaceutical bulletin 20030401

Title: [Osmoregulating reactions following serotonin metabolism inhibition or activation].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20030401

Title: Increases in avoidance responding produced by REM sleep deprivation or serotonin depletion are reversed by administration of 5-hydroxytryptophan.

Journal: Behavioural brain research 20030318

Title: Serotonin-GABA interactions in the modulation of mu- and kappa-opioid analgesia.

Journal: Neuropharmacology 20030301

Title: Serotonin depletion increases respiratory variability in freely moving rats: implications for panic disorder.

Journal: The international journal of neuropsychopharmacology 20030301

Title: Short-term effects of 3,4-methylenedioximethamphetamine on noradrenergic activity in locus coeruleus and hippocampus of the rat.

Journal: Neuroscience letters 20030213

Title: Host brain regulation of dopaminergic grafts function: role of the serotonergic and noradrenergic systems in amphetamine-induced responses.

Journal: Synapse (New York, N.Y.) 20030101

Title: Tricyclic analogs cyclobenzaprine, amitriptyline and cyproheptadine inhibit the spinal reflex transmission through 5-HT(2) receptors.

Journal: European journal of pharmacology 20030101

Title: 5-HT1 and 5-HT2 receptor activation reduces N-methyl-D-aspartate (NMDA)-stimulated LH secretion in prepubertal male and female rats.

Journal: European journal of endocrinology 20030101

Title: Prenatal serotonin depletion changes the behavioral response in the nociceptive formalin test in rats.

Journal: Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20030101

Title: Decreased serotonin level during pregnancy alters morphological and functional characteristics of tonic nociceptive system in juvenile offspring of the rat.

Journal: Reproductive biology and endocrinology : RB&E 20030101

Title: Synaptic loss following depletion of noradrenaline and/or serotonin in the rat visual cortex: a quantitative electron microscopic study.

Journal: Neuroscience 20030101

Title: Depletion of endogenous serotonin synthesis with p-CPA attenuates upregulation of constitutive isoform of heme oxygenase-2 expression, edema formation and cell injury following a focal trauma to the rat spinal cord.

Journal: Acta neurochirurgica. Supplement 20030101

Title: Neuronal and inducible nitric oxide synthase immunoreactivity following serotonin depletion.

Journal: Brain research 20021220

Title: Modulation of serotonin 2C receptor editing by sustained changes in serotonergic neurotransmission.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20021215

Title: Effects of altered photoperiod and temperature, serotonin-affecting drugs, and melatonin on brain tyrosine hydroxylase activity in female catfish, Heteropneustes fossilis: a study correlating ovarian activity changes.

Journal: The Journal of experimental zoology 20021101

Title: Pharmacological blockage of serotonin biosynthesis and circadian changes in oxaliplatin toxicity in rats.

Journal: Chronobiology international 20021101

Title: MDMA- and p-chlorophenylalanine-induced reduction in 5-HT concentrations: effects on serotonin transporter densities.

Journal: European journal of pharmacology 20021025

Title: Neither increased nor decreased availability of cortical serotonin (5HT) disturbs barrel field formation in isocaloric undernourished rat pups.

Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20021001

Title: Modulation of serotonergic projection from dorsal raphe nucleus to basolateral amygdala on sleep-waking cycle of rats.

Journal: Brain research 20020726

Title: Effects of genetic background on neonatal Borna disease virus infection-induced neurodevelopmental damage. II. Neurochemical alterations and responses to pharmacological treatments.

Journal: Brain research 20020719

Title: Decreased marble burying behavior in female mice lacking neuromedin-B receptor (NMB-R) implies the involvement of NMB/NMB-R in 5-HT neuron function.

Journal: Brain research 20020628

Title: Postural modifications and neuronal excitability changes induced by a short-term serotonin depletion during neonatal development in the rat.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020615

Title: The inhibition of tryptophan hydroxylase, not protein synthesis, reduces the brain trapping of alpha-methyl-L-tryptophan: an autoradiographic study.

Journal: Neurochemistry international 20020601

Title: Modulation of 5-HT4 receptor function in the rat isolated ileum by fluoxetine: the involvement of endogenous 5-hydroxytryptamine.

Journal: British journal of pharmacology 20020501

Title: Descending 5-hydroxytryptamine raphe inputs repress the expression of serotonergic neurons and slow the maturation of inhibitory systems in mouse embryonic spinal cord.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020401

Title: Depletion of 5-HT disrupts prepulse inhibition in rats: dependence on the magnitude of depletion, and reversal by a 5-HT precursor.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20020301

Title: Activation by serotonin and noradrenaline of vasopressin and oxytocin expression in the mouse paraventricular and supraoptic nuclei.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020301

Title: GABA(B) receptors in the median raphe nucleus: distribution and role in the serotonergic control of hippocampal activity.

Journal: Neuroscience 20020101

Title: Lack of 5-HT(1B) receptor and of serotonin transporter have different effects on the segregation of retinal axons in the lateral geniculate nucleus compared to the superior colliculus.

Journal: Neuroscience 20020101

Title: Assessment of spinal cord pathology following trauma using early changes in the spinal cord evoked potentials: a pharmacological and morphological study in the rat.

Journal: Muscle & nerve. Supplement 20020101

Title: [Behavioral effects of L-tryptophan and p-chlorophenylalanine after adrenalectomy or dexamethasone administration in rats].

Journal: Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20020101

Title: Self-biting induced by activation of L-type calcium channels in mice: serotonergic influences.

Journal: Developmental neuroscience 20020101

Title: Involvement of serotonergic and dopaminergic mechanisms in hyperthermia induced by a serotonin-releasing drug, p-chloroamphetamine in mice.

Journal: European journal of pharmacology 20011102

Title: Estradiol and para-chlorophenylalanine downregulate the expression of brain aromatase and estrogen receptor-alpha mRNA during the critical period of feminization in tilapia (Oreochromis mossambicus).

Journal: Neuroendocrinology 20011101

Title: Serotonin mediates oestrogen stimulation of cell proliferation in the adult dentate gyrus.

Journal: The European journal of neuroscience 20011101

Title: p-Chlorophenylalanine eliminates long-term modulation of the exercise ventilatory response in goats.

Journal: Respiration physiology 20011101

Title: Role of monoamine oxidase inhibition and monoamine depletion in fenfluramine-induced neurotoxicity and serotonin release.

Journal: Pharmacology & toxicology 20011101

Title: Altered responsiveness to 5-HT at the crayfish neuromuscular junction due to chronic p-CPA and m-CPP treatment.

Journal: Brain research 20011019

Title: Effects of serotonin synthesis blockade on interleukin-1 beta action in the brain of rats.

Journal: Brain research 20011012

Title: Antidepressant-like behavioral effects in 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B) receptor mutant mice.

Journal: The Journal of pharmacology and experimental therapeutics 20010901

Title: Barrel pattern formation requires serotonin uptake by thalamocortical afferents, and not vesicular monoamine release.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010901

Title: Altered respiratory activity and respiratory regulations in adult monoamine oxidase A-deficient mice.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010715

Title: In vivo resetting of the hamster circadian clock by 5-HT7 receptors in the suprachiasmatic nucleus.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010715

Title: Effect of serotonin depletion by p-chlorophenylalanine on serum prolactin levels in estrogen-treated ovariectomized rats: insights concerning the serotoninergic, dopaminergic and opioid systems.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20010601

Title: Phenytoin inhibits isolation-induced aggression specifically in rats with low serotonin.

Journal: Neuroreport 20010508

Title: Methylenedioxymethamphetamine-induced suppression of interleukin-1beta and tumour necrosis factor-alpha is not mediated by serotonin.

Journal: European journal of pharmacology 20010420

Title: Effect of serotonin depletion on nitric oxide induced cerebrovascular nociceptive response.

Journal: Neuroreport 20010417

Title: Reduced brain serotonin activity disrupts prepulse inhibition of the acoustic startle reflex. Effects of 5,7-dihydroxytryptamine and p-chlorophenylalanine.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010401

Title: Pharmacological studies on the monoaminergic influence on the synthesis and expression of neuropeptide Y and corticotropin releasing factor in rat brain amygdala.

Journal: Neuropeptides 20010401

Title: Effects of MDL 73005 on water-maze performances and locomotor activity in scopolamine-treated rats.

Journal: Pharmacology, biochemistry, and behavior 20010401

Title: Disruption of neuroendocrine control of luteinizing hormone secretion by aroclor 1254 involves inhibition of hypothalamic tryptophan hydroxylase activity.

Journal: Biology of reproduction 20010301

Title: Apomorphine-induced aggressive behaviour in para-chlorophenylalanine-treated male rats: implications to brain.

Journal: Pharmacology & toxicology 20010301

Title: Effects of p-chlorophenylalanine on striatal acetylcholinesterase activity and on biogenic amine levels in nuclei raphe and caudate-putamen during physostigmine-induced tremor in rats.

Journal: Neuroscience letters 20010216

Title: Endogenous 5-HT tonically inhibits spontaneous firing activity of dorsal hippocampus CA1 pyramidal neurons through stimulation of 5-HT(1A) receptors in quiet awake rats: in vivo electrophysiological evidence.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010201

Title: Behavioral effects of para-chlorophenylalanine in gonadectomized male rats.

Journal: Bulletin of experimental biology and medicine 20010201

Title: Nitric oxide modulates lithium-induced conditioned taste aversion.

Journal: Behavioural brain research 20010129

Title: Increased nitric oxide synthase activity in a model of serotonin depletion.

Journal: Brain research bulletin 20010115

Title: The antidepressant activity of inositol in the forced swim test involves 5-HT(2) receptors.

Journal: Behavioural brain research 20010108

Title: Serotonergic mechanism in imipramine induced antinociception in rat tail flick test.

Journal: Indian journal of physiology and pharmacology 20010101

Title: Acute antidepressant-like and antianxiety-like effects of tryptophan in mice.

Journal: Pharmacology 20010101

Title: Evaluation of genotoxity and mutagenicity of DL-p-chlorophenylalanine, its methyl ester and some N-acyl derivatives.

Journal: Acta biologica Hungarica 20010101

Title: [Effect of serotonin on the development of luteinizing hormone-releasing hormone system in Wistar rat embryos].

Journal: Zhurnal evoliutsionnoi biokhimii i fiziologii 20010101

Title: p-Chlorophenylalanine and fluoxetine inhibit D-fenfluramine-induced Fos expression in the paraventricular nucleus, cingulate cortex and frontal cortex but not in other forebrain and brainstem regions.

Journal: Brain research 19971107

Title: Effect of p-chlorophenylalanine at moderate dosage on 5-HT and 5-HIAA concentrations in brain regions of control and p-chloroamphetamine treated rats.

Journal: Neuropharmacology 19960301

Title: d-Fenfluramine- and d-norfenfluramine-induced hypophagia: differential mechanisms and involvement of postsynaptic 5-HT receptors.

Journal: European journal of pharmacology 19930921

Title: A functional interaction between GABA and 5-HT in inhibiting picrotoxin-induced myoclonus in rats.

Journal: Indian journal of physiology and pharmacology 19900401

Title: Influence of (-)-sulpiride and YM-09151-2 on stereotyped behavior in chicks and catalepsy in rats.

Journal: Japanese journal of pharmacology 19870201

Title: Stress by restraining potentiates morphine catalepsy in rats.

Journal: Experientia 19851215

Title: (+)-6-fluorotryptophan, an inhibitor of tryptophan hydroxylase: sleep and wakefulness in the rat.

Journal: Neuropharmacology 19810401

Title: Alteration of lidocaine- or procaine-induced convulsions by manipulation of brain amines.

Journal: Journal of dental research 19810201

Title: Serotoninergic mechanisms of beta-endorphin- and clonidine-induced analgesia in rats.

Journal: Pharmacology 19800101

Title: Effect of brain 5-hydroxytryptamine alterations on reflex bradycardia in rats.

Journal: The American journal of physiology 19790501

Title: Effects of brain serotonin alterations on prostaglandin E1-induced bradycardia in rats.

Journal: The Journal of pharmacology and experimental therapeutics 19790201

Title: Central action of narcotic analgesics. V. Participation of serotonin in the mechanism of action of narcotic analgesics.

Journal: Polish journal of pharmacology and pharmacy 19790101

Title: Antagonism of pentobarbital-induced hormonal changes by TRH in rats.

Journal: European journal of pharmacology 19771015

Title: [Analysis of apomorphine aggessiveness and stereotypy: role of serotonin- and cholinergic systems of the brain].

Journal: Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 19770101

Title: Differentiaton of neuropharmacological actions of apomorphine and d-amphetamine.

Journal: Pharmacology, biochemistry, and behavior 19761201

Title: Effect of humoral modulators of morphine-induced increase in locomotor activity of mice.

Journal: Japanese journal of pharmacology 19761001

Title: Potentiation of amphetamine-induced hyperactivity by acute but not by chronic para-chlorophenylalanine treatment in the rat.

Journal: Life sciences 19760401

Title: The effects of DL-p-chlorophenylalanine and DL-alpha-methyl-p-tyrosine on the brain catecholamine, serotonin and free amino acid contents in rat.

Journal: Psychopharmacologia 19751231

Title: Effects of aminergic drugs and glutamic acid on audiogenic seizures induced by early exposure to ethanol.

Journal: Epilepsia 19750301

Title: L-dopa hypotension in dogs: evidence for mediation through 5-HT release.

Journal: Archives internationales de pharmacodynamie et de therapie 19741101

Title: [Brain amines and apomorphine-induced intraspecific aggressive behavior in the rat (author's transl)].

Journal: Psychopharmacologia 19740111

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Tags:23633-07-0 Molecular Formula|23633-07-0 MDL|23633-07-0 SMILES|23633-07-0 2-Amino-3-(4-chlorophenyl)propanoic acid hydrochloride