Home Other Building Blocks 2373-89-9
2373-89-9,MFCD00025815
Catalog No.:AA003KCU

2373-89-9 | 4,4'-Dimethoxychalcone

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
98%(GC)
in stock  
$23.00   $16.00
- +
5g
95+%
in stock  
$37.00   $26.00
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25g
98%(GC)
in stock  
$118.00   $83.00
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100g
98%(GC)
in stock  
$404.00   $283.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003KCU
Chemical Name:
4,4'-Dimethoxychalcone
CAS Number:
2373-89-9
Molecular Formula:
C17H16O3
Molecular Weight:
268.3071
MDL Number:
MFCD00025815
SMILES:
COc1ccc(cc1)/C=C/C(=O)c1ccc(cc1)OC
NSC Number:
87339
Properties
Properties
 
Form:
Solid  
MP:
101℃  

Computed Properties
 
Complexity:
321  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
3  
Rotatable Bond Count:
5  
XLogP3:
3  

Downstream Synthesis Route

[1]JournaloftheChemicalSociety,1958,p.2606,2608

[1]CollectionofCzechoslovakChemicalCommunications,1987,vol.52,p.1021-1025

2373-89-9    3215-64-3   
2-(2,4-Dichloro-phenyl)-3,5-bis-(4-methoxy-phenyl)-5-oxo-pentanenitrile 

[1]BulletindelaSocieteChimiquedeFrance,1987,p.787-790

[1]Sayed,G.H.;Kjosen,H.[JournalfurpraktischeChemie(Leipzig1954),1980,vol.322,#5,p.716-722]

[1]Gonda,Zsombor;Novák,Zoltán[Chemistry-AEuropeanJournal,2015,vol.21,#47,p.16801-16806]

Literature

Title: Design, synthesis, and biological evaluation of chalcone oxime derivatives as potential immunosuppressive agents.

Journal: Bioorganic & medicinal chemistry letters 20120501

Title: Combretastatin-like chalcones as inhibitors of microtubule polymerization. Part 1: synthesis and biological evaluation of antivascular activity.

Journal: Bioorganic & medicinal chemistry 20091115

Title: Antimalarial alkoxylated and hydroxylated chalcones [corrected]: structure-activity relationship analysis.

Journal: Journal of medicinal chemistry 20011206

Title: Carmona-Gutierrez D, et al. The flavonoid 4,4'-dimethoxychalcone promotes autophagy-dependent longevity across species. Nat Commun. 2019 Feb 19;10(1):651.

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SDS
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