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2380-78-1,MFCD00002903
Catalog No.:AA00I4J3

2380-78-1 | 4-Hydroxy-3-methoxyphenethanol

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Purity
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Price(USD)
Quantity
  
1mg
95%
in stock  
$24.00   $17.00
- +
10mg
95%
in stock  
$85.00   $60.00
- +
50mg
95%
in stock  
$151.00   $106.00
- +
500mg
97%
in stock  
$156.00   $109.00
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10g
97%
in stock  
$1,343.00   $940.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00I4J3
Chemical Name:
4-Hydroxy-3-methoxyphenethanol
CAS Number:
2380-78-1
Molecular Formula:
C9H12O3
Molecular Weight:
168.1898
MDL Number:
MFCD00002903
SMILES:
OCCc1ccc(c(c1)OC)O
Properties
Properties
 
BP:
316.8 °C at 760 mmHg  
Form:
Solid  
MP:
40-42 °C(lit.)  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
127  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
0.5  

Downstream Synthesis Route

[1]Schweitzer,Stefan;Voss,Gundula;Gerlach,Hans[LiebigsAnnalenderChemie,1994,#2,p.189-192]

[1]Walpole;Wrigglesworth;Bevan;Campbell;Dray;James;Masdin;Perkins;Winter[JournalofMedicinalChemistry,1993,vol.36,#16,p.2373-2380]

2380-78-1    105-36-2   
4-(2-Hydroxy-ethyl)-2-methoxy-phenoxy-aceticacidethylester 

[1]Sato;Kawashima;Goto;Yamane;Chiba;Jinno;Satake;Imanishi;Iwata[ChemicalandPharmaceuticalBulletin,1994,vol.42,#3,p.521-529]

2380-78-1    67874-68-4   
2-phenoxymethyl-2H-7,8-dihydrobenzopyran 

[1]Arnoldi,Anna;Bassoli,Angela;Borgonovo,Gigliola;Drew,MichaelG.B.;Merlini,Lucio;Morini,Gabriella[JournalofAgriculturalandFoodChemistry,1998,vol.46,#10,p.4002-4010]

2380-78-1   
C9H9(2)H3O3 

[1]Tuck,KellieL.;Hayball,PeterJ.[Journaloflabelledcompoundsandradiopharmaceuticals,2001,vol.44,#14,p.1005-1012]

Literature

Title: Picea mariana bark: a new source of trans-resveratrol and other bioactive polyphenols.

Journal: Food chemistry 20121201

Title: Dietary polyphenols as modulators of brain functions: biological actions and molecular mechanisms underpinning their beneficial effects.

Journal: Oxidative medicine and cellular longevity 20120101

Title: Ethnobotanical survey, chemical composition, and antioxidant capacity of methanolic extract of the root bark of Annona cuneata Oliv.

Journal: Journal of medicinal food 20111101

Title: Absorption and metabolism of olive oil secoiridoids in the small intestine.

Journal: The British journal of nutrition 20110601

Title: Phenylpropanoid glycoside analogues: enzymatic synthesis, antioxidant activity and theoretical study of their free radical scavenger mechanism.

Journal: PloS one 20110101

Title: Protective effect of simple phenols from extravirgin olive oil against lipid peroxidation in intestinal Caco-2 cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20101001

Title: Antioxidant activities of hydroxytyrosol main metabolites do not contribute to beneficial health effects after olive oil ingestion.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100901

Title: Involvement of ERK, Akt and JNK signalling in H2O2-induced cell injury and protection by hydroxytyrosol and its metabolite homovanillic alcohol.

Journal: Molecular nutrition & food research 20100601

Title: Simultaneous quantification of oleuropein and its metabolites in rat plasma by liquid chromatography electrospray ionization tandem mass spectrometry.

Journal: Biomedical chromatography : BMC 20100501

Title: Human absorption of a supplement containing purified hydroxytyrosol, a natural antioxidant from olive oil, and evidence for its transient association with low-density lipoproteins.

Journal: Pharmacological research 20100401

Title: New insights into honey bee (Apis mellifera) pheromone communication. Is the queen mandibular pheromone alone in colony regulation?

Journal: Frontiers in zoology 20100101

Title: Chemical constituents of Dracocephalum forrestii.

Journal: Planta medica 20091201

Title: Dopamine receptor activation by honey bee queen pheromone.

Journal: Current biology : CB 20090728

Title: Olive oil phenolic compounds inhibit homocysteine-induced endothelial cell adhesion regardless of their different antioxidant activity.

Journal: Journal of agricultural and food chemistry 20090513

Title: Detection and quantification of phenolic compounds in olive oil by high resolution 1H nuclear magnetic resonance spectroscopy.

Journal: Analytica chimica acta 20090209

Title: Convenient synthesis of hydroxytyrosol and its lipophilic derivatives from tyrosol or homovanillyl alcohol.

Journal: Journal of agricultural and food chemistry 20081008

Title: Protective effect of hydroxytyrosol and its metabolite homovanillic alcohol on H(2)O(2) induced lipid peroxidation in renal tubular epithelial cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080901

Title: Inhibition of platelet aggregation by olive oil phenols via cAMP-phosphodiesterase.

Journal: The British journal of nutrition 20080501

Title: Naturally occurring phenylethanoid glycosides: potential leads for new therapeutics.

Journal: Current medicinal chemistry 20080101

Title: New insights into controversies on the antioxidant potential of the olive oil antioxidant hydroxytyrosol.

Journal: Journal of agricultural and food chemistry 20070905

Title: Queen pheromone blocks aversive learning in young worker bees.

Journal: Science (New York, N.Y.) 20070720

Title: Hydroxytyrosol lipophilic analogues: enzymatic synthesis, radical scavenging activity and DNA oxidative damage protection.

Journal: Bioorganic chemistry 20070401

Title: The olive oil antioxidant hydroxytyrosol efficiently protects against the oxidative stress-induced impairment of the NObullet response of isolated rat aorta.

Journal: American journal of physiology. Heart and circulatory physiology 20070401

Title: Effects of insemination quantity on honey bee queen physiology.

Journal: PloS one 20070101

Title: Understanding the logics of pheromone processing in the honeybee brain: from labeled-lines to across-fiber patterns.

Journal: Frontiers in behavioral neuroscience 20070101

Title: Inhibitory effects of Zingiber officinale Roscoe derived components on aldose reductase activity in vitro and in vivo.

Journal: Journal of agricultural and food chemistry 20060906

Title: Minor components of olive oil modulate proatherogenic adhesion molecules involved in endothelial activation.

Journal: Journal of agricultural and food chemistry 20060503

Title: Daily consumption of a high-phenol extra-virgin olive oil reduces oxidative DNA damage in postmenopausal women.

Journal: The British journal of nutrition 20060401

Title: Antagonism between olive oil phenolics and nitric oxide on lymphomonocyte cytosolic calcium.

Journal: Molecular and cellular biochemistry 20051201

Title: Colorimetric evaluation of phenolic content and GC-MS characterization of phenolic composition of alimentary and cosmetic argan oil and press cake.

Journal: Journal of agricultural and food chemistry 20051116

Title: Antioxidant and anti-atherogenic activities of olive oil phenolics.

Journal: International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20050101

Title: Low-molecular-weight components of olive oil mill waste-waters.

Journal: Phytochemical analysis : PCA 20040101

Title: Structural characterization of the metabolites of hydroxytyrosol, the principal phenolic component in olive oil, in rats.

Journal: Journal of agricultural and food chemistry 20020410

Title: Urinary excretion of olive oil phenols and their metabolites in humans.

Journal: Metabolism: clinical and experimental 20011201

Title: Fátima Paiva-Martins, et al. Protective Activity of Hydroxytyrosol Metabolites on Erythrocyte Oxidative-Induced Hemolysis. J Agric Food Chem. 2013 Jul 10;61(27):6636-42.

Title: Rafael De la Torre, et al. Protective Effect of Homovanillyl Alcohol on Cardiovascular Disease and Total Mortality: Virgin Olive Oil, Wine, and Catechol-Methylation. Am J Clin Nutr. 2017 Jun;105(6):1297-1304.

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