Home Indole and Oxindoles 2380-86-1
2380-86-1,MFCD00152101
Catalog No.:AA0034AE

2380-86-1 | 6-Hydroxyindole

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Purity
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100mg
97%
in stock  
$7.00   $5.00
- +
250mg
97%
in stock  
$14.00   $10.00
- +
1g
97%
in stock  
$28.00   $20.00
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5g
97%
in stock  
$126.00   $89.00
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25g
97%
in stock  
$516.00   $362.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0034AE
Chemical Name:
6-Hydroxyindole
CAS Number:
2380-86-1
Molecular Formula:
C8H7NO
Molecular Weight:
133.1473
MDL Number:
MFCD00152101
SMILES:
Oc1ccc2c(c1)[nH]cc2
Properties
Properties
 
Form:
Solid  
MP:
124-130 °C  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
126  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
2  
XLogP3:
2.3  

Upstream Synthesis Route

[1]Patent:WO2016/196890,2016,A1,.Locationinpatent:Page/Pagecolumn101

[1]Patent:US2004/48915,2004,A1,

[1]Patent:EP1541582,2005,A1,.Locationinpatent:Page/Pagecolumn39-40

[2]Patent:EP1541582,2005,A1,.Locationinpatent:Page/Pagecolumn39-40

[3]Patent:EP1541582,2005,A1,.Locationinpatent:Page/Pagecolumn39-40

[4]Patent:EP1541582,2005,A1,.Locationinpatent:Page/Pagecolumn39-40

[5]OrganicProcessResearchandDevelopment,2006,vol.10,#6,p.1178-1183

[6]TetrahedronLetters,2006,vol.47,#6,p.969-972

[7]TetrahedronLetters,2006,vol.47,#6,p.969-972

[8]Patent:EP1541582,2005,A1,.Locationinpatent:Page/Pagecolumn37

[9]OrganicProcessResearchandDevelopment,2006,vol.10,#6,p.1178-1183

[1]JournalofNaturalProducts,2017,vol.80,#8,p.2384-2388

[2]JournalofMedicinalChemistry,2018,vol.61,#13,p.5733-5750

[3]BioorganicandMedicinalChemistry,2015,vol.23,#13,p.3322-3336

[1]JournalofMedicinalChemistry,1992,vol.35,#13,p.2419-2439

Downstream Synthesis Route

[1]JournaloftheChemicalSociety,1948,p.1605,1608

[1]JournalofMedicinalChemistry,1994,vol.37,p.2011-2032

[2]Patent:WO2013/150529,2013,A2.Locationinpatent:Page/Pagecolumn26;29

[3]HelveticaChimicaActa,1955,vol.38,p.1452,1469

[4]OrganicProcessResearchandDevelopment,2006,vol.10,p.1178-1183

[1]Brown;Cronk;Aharony;Snyder[JournalofMedicinalChemistry,1992,vol.35,#13,p.2419-2439]

[1]JournalofMedicinalChemistry,1994,vol.37,p.2011-2032

Literature

Title: Target-triggered deprotonation of 6-hydroxyindole-based BODIPY: specially switch on NIR fluorescence upon selectively binding to Zn2+.

Journal: Chemical communications (Cambridge, England) 20121011

Title: 6-Hydroxyindole-based borondipyrromethene: synthesis and spectroscopic studies.

Journal: Organic & biomolecular chemistry 20120114

Title: N-(3,5-dihydroxybenzoyl)-6-hydroxytryptamine as a novel human tyrosinase inhibitor that inactivates the enzyme in cooperation with l-3,4-dihydroxyphenylalanine.

Journal: Chemical & pharmaceutical bulletin 20101101

Title: Bicyclic compounds repress membrane vesicle production and Pseudomonas quinolone signal synthesis in Pseudomonas aeruginosa.

Journal: FEMS microbiology letters 20100301

Title: Inhibitory effect of hydroxyindoles and their analogues on human melanoma tyrosinase.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20100101

Title: Monoindole alkaloids from a marine sponge Spongosorites sp.

Journal: Marine drugs 20070601

Title: Hyrtioerectines A-C, cytotoxic alkaloids from the red sea sponge hyrtioserectus.

Journal: Journal of natural products 20050901

Title: A facile preparation of 1-(6-hydroxyindol-1-yl)-2,2-dimethylpropan-1-one.

Journal: Chemical & pharmaceutical bulletin 20030101

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SDS
Tags:2380-86-1 Molecular Formula|2380-86-1 MDL|2380-86-1 SMILES|2380-86-1 6-Hydroxyindole |Heterocyclic_Building_Blocks