Home Indole and Oxindoles 244-63-3
244-63-3,MFCD00004956
Catalog No.:AA0034CG

244-63-3 | 9H-Pyrido[3,4-b]indole

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250mg
97
in stock  
$10.00   $7.00
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1g
98%
in stock  
$23.00   $16.00
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5g
98%
in stock  
$102.00   $71.00
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10g
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$200.00   $140.00
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25g
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$428.00   $300.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0034CG
Chemical Name:
9H-Pyrido[3,4-b]indole
CAS Number:
244-63-3
Molecular Formula:
C11H8N2
Molecular Weight:
168.1946
MDL Number:
MFCD00004956
SMILES:
c1ccc2c(c1)[nH]c1c2ccnc1
NSC Number:
84417
Properties
Properties
 
BP:
391.3°C at 760 mmHg  
Form:
Solid  
MP:
199-201 °C  
Refractive Index:
1.5200 (estimate)  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
193  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
XLogP3:
3.2  

Downstream Synthesis Route

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Journal: The journal of physical chemistry. B 20090528

Title: Biological activity of 1,2,3,4-tetrahydro-beta-carboline-3-carboxamides against Trypanosoma cruzi.

Journal: Acta tropica 20090401

Title: 5-Bromo-8-methoxy-1-methyl-beta-carboline, an alkaloid from the New Zealand marine bryozoan Pterocella vesiculosa.

Journal: Journal of natural products 20090401

Title: Dual emission of temperature-induced betacarboline self-associated hydrogen bond aggregates.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20090301

Title: Analysis of heterocyclic amines and beta-carbolines by liquid chromatography-mass spectrometry in cooked meats commonly consumed in Korea.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20090301

Title: Synthesis and in vitro cytotoxic evaluation of novel 3,4,5-trimethoxyphenyl substituted beta-carboline derivatives.

Journal: European journal of medicinal chemistry 20090201

Title: The effect of temperature on the stability of compounds used as UV-MALDI-MS matrix: 2,5-dihydroxybenzoic acid, 2,4,6-trihydroxyacetophenone, alpha-cyano-4-hydroxycinnamic acid, 3,5-dimethoxy-4-hydroxycinnamic acid, nor-harmane and harmane.

Journal: Journal of mass spectrometry : JMS 20090201

Title: Zamamidines A and B, new manzamine alkaloids from the sponge Amphimedon species.

Journal: Organic letters 20090101

Title: Antiplatelet activity of beta-carboline alkaloids from Perganum harmala: a possible mechanism through inhibiting PLCgamma2 phosphorylation.

Journal: Vascular pharmacology 20090101

Title: Gas chromatographic analysis of dimethyltryptamine and beta-carboline alkaloids in ayahuasca, an Amazonian psychoactive plant beverage.

Journal: Phytochemical analysis : PCA 20090101

Title: Floral nectar composition of Peganum harmala L.

Journal: Natural product research 20090101

Title: beta-carboline alkaloid-enriched extract from the amazonian rain forest tree pao pereira suppresses prostate cancer cells.

Journal: Journal of the Society for Integrative Oncology 20090101

Title: Optimized HPLC method for analysis of polar and nonpolar heterocyclic amines in cooked meat products.

Journal: Journal of AOAC International 20090101

Title: Analysis of an RNA adduct formed from aminophenylnorharman.

Journal: Nucleic acids symposium series (2004) 20090101

Title: Synthesis of novel tadalafil analogues and their evaluation as phosphodiesterase inhibitors and anticancer agents.

Journal: Arzneimittel-Forschung 20090101

Title: Pharmacological alterations of anxious behaviour in mice depending on both strain and the behavioural situation.

Journal: PloS one 20090101

Title: Smoking induces long-lasting effects through a monoamine-oxidase epigenetic regulation.

Journal: PloS one 20090101

Title: Acquired auditory-visual synesthesia: A window to early cross-modal sensory interactions.

Journal: Psychology research and behavior management 20090101

Title: Synthesis and cytotoxic activities of 1-benzylidine substituted beta-carboline derivatives.

Journal: Bioorganic & medicinal chemistry letters 20081215

Title: Parallel factor analysis of spider fluorophores.

Journal: Journal of photochemistry and photobiology. B, Biology 20081211

Title: Mana-Hox displays anticancer activity against prostate cancer cells through tubulin depolymerization and DNA damage stress.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20081201

Title: DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine.

Journal: The FEBS journal 20081201

Title: The role of prior stressor controllability and the dorsal raphé nucleus in sucrose preference and social exploration.

Journal: Behavioural brain research 20081103

Title: 3D and quantum QSAR of non-benzodiazepine compounds.

Journal: European journal of medicinal chemistry 20081101

Title: Antifungal activity of the termite alkaloid norharmane against the mycelial growth of Metarhizium anisopliae and Aspergillus nomius.

Journal: Journal of invertebrate pathology 20081101

Title: Effect of Peganum harmala or its beta-carboline alkaloids on certain antibiotic resistant strains of bacteria and protozoa from poultry.

Journal: Phytotherapy research : PTR 20081101

Title: Oxidative metabolism of the bioactive and naturally occurring beta-carboline alkaloids, norharman and harman, by human cytochrome P450 enzymes.

Journal: Chemical research in toxicology 20081101

Title: Metal-catalyzed reaction of N-(2-indolyl)methyl, N-bis(trimethylsilyl)methyl diazoamides: an entry into the beta-carboline ring system.

Journal: Chemical communications (Cambridge, England) 20081021

Title: Identification of N,N-dimethyltryptamine and beta-carbolines in psychotropic ayahuasca beverage.

Journal: Biomedical chromatography : BMC 20081001

Title: Furan oligomers and beta-carbolines from terrestrial streptomycetes.

Journal: Journal of natural products 20080901

Title: A versatile cyclodehydration reaction for the synthesis of isoquinoline and beta-carboline derivatives.

Journal: Organic letters 20080821

Title: A case of beta-carboline alkaloid intoxication following ingestion of Peganum harmala seed extract.

Journal: Forensic science international 20080806

Title: Cytotoxicity of the beta-carboline alkaloids harmine and harmaline in human cell assays in vitro.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20080801

Title: Potent and selective antiplasmodial activity of the cyanobacterial alkaloid nostocarboline and its dimers.

Journal: Bioorganic & medicinal chemistry letters 20080801

Title: The effects of rivastigmine plus selegiline on brain acetylcholinesterase, (Na, K)-, Mg-ATPase activities, antioxidant status, and learning performance of aged rats.

Journal: Neuropsychiatric disease and treatment 20080801

Title: The use of natural product scaffolds as leads in the search for trypanothione reductase inhibitors.

Journal: Bioorganic & medicinal chemistry 20080715

Title: Quantitative structure-activity relationship studies of a series of non-benzodiazepine structural ligands binding to benzodiazepine receptor.

Journal: European journal of medicinal chemistry 20080701

Title: Photophysics of a beta-carboline based non-ionic probe in anionic and zwitterionic liposome membranes.

Journal: Chemistry and physics of lipids 20080701

Title: Nonsymmetrical beta-carboline dimers from an Ascidian, Didemnum sp.

Journal: Journal of natural products 20080701

Title: Quantification of heterocyclic aromatic amines in fried meat by HPTLC/UV-FLD and HPLC/UV-FLD: a comparison of two methods.

Journal: Journal of agricultural and food chemistry 20080625

Title: Effects of harman and norharman on dopamine biosynthesis and L-DOPA-induced cytotoxicity in PC12 cells.

Journal: European journal of pharmacology 20080610

Title: Indolealkylamines: biotransformations and potential drug-drug interactions.

Journal: The AAPS journal 20080601

Title: Influence of the presence of methyl cyclodextrins in high-performance liquid chromatography mobile phases on the separation of beta-carboline alkaloids.

Journal: Journal of chromatography. A 20080530

Title: Electronic structure of the ground and excited states of beta-carboline.

Journal: Chemphyschem : a European journal of chemical physics and physical chemistry 20080421

Title: Synthesis of eudistomin D analogues and its effects on adenosine receptors.

Journal: Bioorganic & medicinal chemistry 20080401

Title: Gamma-carboline derivatives with anti-bovine viral diarrhea virus (BVDV) activity.

Journal: Bioorganic & medicinal chemistry 20080401

Title: Effect of surfactant chain length on the binding interaction of a biological photosensitizer with cationic micelles.

Journal: The journal of physical chemistry. B 20080327

Title: Daytime Ayahuasca administration modulates REM and slow-wave sleep in healthy volunteers.

Journal: Psychopharmacology 20080201

Title: The enantioselective total synthesis of a beta-carboline alkaloid, (S)-(-)-dichotomine C.

Journal: Chemical & pharmaceutical bulletin 20080201

Title: Beta-carboline alkaloids from a Korean tunicate Eudistoma sp.

Journal: Journal of natural products 20080201

Title: Strictosidine synthase: mechanism of a Pictet-Spengler catalyzing enzyme.

Journal: Journal of the American Chemical Society 20080116

Title: A newly developed assay for the quantitative determination of antimicrobial (anticyanobacterial) activity of both hydrophilic and lipophilic test compounds without any restriction.

Journal: Microbiological research 20080101

Title: Screening of microalgae for species excreting norharmane, a manifold biologically active indole alkaloid.

Journal: Microbiological research 20080101

Title: Determination of beta-carboline alkaloids in fruiting bodies of Hygrophorus spp. by liquid chromatography/electrospray ionisation tandem mass spectrometry.

Journal: Phytochemical analysis : PCA 20080101

Title: Effect of norharmane in vitro on juvenile hormone epoxide hydrolase activity in the lower termite, Reticulitermes speratus.

Journal: Journal of insect science (Online) 20080101

Title: Degradation of heterocyclic aromatic amines in oil under storage and frying conditions and reduction of their mutagenic potential.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20071101

Title: Identification and occurrence of beta-carboline alkaloids in raisins and inhibition of monoamine oxidase (MAO).

Journal: Journal of agricultural and food chemistry 20071017

Title: Tumor-initiating potency of a novel heterocyclic amine, aminophenylnorharman in mouse colonic carcinogenesis model.

Journal: International journal of cancer 20071015

Title: Direct experimental evidence for a heterogeneous reaction of ozone with bromide at the air-aqueous interface.

Journal: The journal of physical chemistry. A 20071004

Title: Coupled hydrogen-bonding interactions between beta-carboline derivatives and acetic acid.

Journal: Magnetic resonance in chemistry : MRC 20071001

Title: Synthesis of 3,8,9-trisubstituted-1,7,9-triaza-fluorene-6-carboxylic acid derivatives as a new class of insulin secretagogues.

Journal: Bioorganic & medicinal chemistry 20070901

Title: Towards GAG glycomics: analysis of highly sulfated heparins by MALDI-TOF mass spectrometry.

Journal: Glycobiology 20070901

Title: Brunneins A-C, beta-carboline alkaloids from Cortinarius brunneus.

Journal: Journal of natural products 20070901

Title: Sustained inhibition of brotizolam induced anterograde amnesia by norharmane and retrograde amnesia by L-glutamic acid in mice.

Journal: Behavioural brain research 20070822

Title: Validation of an ion-pair liquid chromatography-electrospray-tandem mass spectrometry method for the determination of heterocyclic aromatic amines in meat-based infant foods.

Journal: Food additives and contaminants 20070801

Title: DH334, a beta-carboline anti-cancer drug, inhibits the CDK activity of budding yeast.

Journal: Cancer biology & therapy 20070801

Title: Rapid identification of enzyme variants for reengineered alkaloid biosynthesis in periwinkle.

Journal: Chemistry & biology 20070801

Title: Theoretical and UV spectral study of isomeric 1-(quinolinyl)-beta-carbolines conformations.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070701

Title: Differential effects of dopamine melanin on norharman-induced toxicity in PC12 cells.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20070701

Title: Antioxidant properties of beta-carboline alkaloids are related to their antimutagenic and antigenotoxic activities.

Journal: Mutagenesis 20070701

Title: Effect of cyclodextrin nanocavity confinement on the photophysics of a beta-carboline analogue: a spectroscopic study.

Journal: The journal of physical chemistry. B 20070628

Title: Neuroprotective effects of the beta-carboline abecarnil studied in cultured cortical neurons and organotypic retinal cultures.

Journal: Neuropharmacology 20070601

Title: Golden opportunities in natural product synthesis: first total synthesis of (-)-isocyclocapitelline and (-)-isochrysotricine by gold-catalyzed allene cycloisomerization.

Journal: Organic & biomolecular chemistry 20070521

Title: Synthesis of hybrid molecules of caffeine and eudistomin D and its effects on adenosine receptors.

Journal: Bioorganic & medicinal chemistry 20070501

Title: N-methyltetrahydro-beta-carboline analogs of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin are oxidized to neurotoxic beta-carbolinium cations by heme peroxidases.

Journal: Biochemical and biophysical research communications 20070427

Title: Surfactant chain-length-dependent modulation of the prototropic transformation of a biological photosensitizer: norharmane in anionic micelles.

Journal: Langmuir : the ACS journal of surfaces and colloids 20070424

Title: Flazinamide, a novel beta-carboline compound with anti-HIV actions.

Journal: Biochemical and biophysical research communications 20070420

Title: From pyrroles to 1-oxo-2,3,4,9-tetrahydro-1H-beta-carbolines: a new class of orally bioavailable mGluR1 antagonists.

Journal: Bioorganic & medicinal chemistry letters 20070415

Title: Heterocyclic amines in griddled beef steak analysed using a single extract clean-up procedure.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070401

Title: Solid-phase fluorescence and ionization efficiency in negative-ion matrix-assisted laser desorption/ionization of neutral oligosaccharides: interaction between beta-carboline matrix and ammonium salt.

Journal: Journal of the American Society for Mass Spectrometry 20070401

Title: Factors influencing the norharman and harman contents in espresso coffee.

Journal: Journal of agricultural and food chemistry 20070307

Title: Determination of beta-carboline alkaloids in foods and beverages by high-performance liquid chromatography with electrochemical detection at a glassy carbon electrode modified with carbon nanotubes.

Journal: Analytica chimica acta 20070307

Title: Anticonvulsants in sports: ethical considerations.

Journal: Epilepsy & behavior : E&B 20070301

Title: Binding interaction of a biological photosensitizer with serum albumins: a biophysical study.

Journal: Biomacromolecules 20070301

Title: Methylglyoxal-derived beta-carbolines formed from tryptophan and its derivates in the Maillard reaction.

Journal: Amino acids 20070201

Title: Validation of a new planar chromatographic method for quantification of the heterocyclic aromatic amines most frequently found in meat.

Journal: Analytical and bioanalytical chemistry 20070201

Title: Synthesis and evaluation of antitumor activity of novel N-acyllavendamycin analogues and quinoline-5,8-diones.

Journal: Bioorganic & medicinal chemistry 20070101

Title: Risk assessment of ritual use of oral dimethyltryptamine (DMT) and harmala alkaloids.

Journal: Addiction (Abingdon, England) 20070101

Title: Detection of aminophenylnorharman, a possible endogenous mutagenic and carcinogenic compound, in human urine samples.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20070101

Title: beta-Carboline alkaloids: biochemical and pharmacological functions.

Journal: Current medicinal chemistry 20070101

Title: From the behavioral pharmacology of beta-carbolines to seizures, anxiety, and memory.

Journal: TheScientificWorldJournal 20070101

Title: Identification of the endogenous key substrates of the human organic cation transporter OCT2 and their implication in function of dopaminergic neurons.

Journal: PloS one 20070101

Title: Plants used traditionally to treat malaria in Brazil: the archives of Flora Medicinal.

Journal: Journal of ethnobiology and ethnomedicine 20070101

Title: Mapping of oxidative stress responses of human tumor cells following photodynamic therapy using hexaminolevulinate.

Journal: BMC genomics 20070101

Title: Pharmacology of the beta-carboline FG-7,142, a partial inverse agonist at the benzodiazepine allosteric site of the GABA A receptor: neurochemical, neurophysiological, and behavioral effects.

Journal: CNS drug reviews 20070101

Title: Synthesis, crystal structure and biological activity of beta-carboline based selective CDK4-cyclin D1 inhibitors.

Journal: Organic & biomolecular chemistry 20061221

Title: Efficient and sensitive method for quantitative analysis of alkaloids in hardinggrass (Phalaris aquatica L.).

Journal: Journal of agricultural and food chemistry 20061213

Title: Monoamine oxidase A rather than monoamine oxidase B inhibition increases nicotine reinforcement in rats.

Journal: The European journal of neuroscience 20061201

Title: Receptor-based pharmacophores for serotonin 5-HT7R antagonists-implications to selectivity.

Journal: Journal of medicinal chemistry 20061116

Title: 6-Hydroxy- and 6-methoxy-beta-carbolines as acetyl- and butyrylcholinesterase inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20061115

Title: Anti-prostate cancer activity of a beta-carboline alkaloid enriched extract from Rauwolfia vomitoria.

Journal: International journal of oncology 20061101

Title: Activation of aminophenylnorharman, aminomethylphenylnorharman and aminophenylharman to genotoxic metabolites by human N-acetyltransferases and cytochrome P450 enzymes expressed in Salmonella typhimurium umu tester strains.

Journal: Mutagenesis 20061101

Title: Effects of beta-carboline alkaloids on the object recognition task in mice.

Journal: Life sciences 20061026

Title: Effect of red wine marinades on the formation of heterocyclic amines in fried chicken breast.

Journal: Journal of agricultural and food chemistry 20061018

Title: Synthesis and cytotoxic activities of beta-carboline amino acid ester conjugates.

Journal: Bioorganic & medicinal chemistry 20061015

Title: Design of beta-carboline derivatives as DNA-targeting antitumor agents.

Journal: European journal of medicinal chemistry 20061001

Title: Parkinson's disease-like syndrome in rats induced by 2,9-dimethyl-beta-carbolinium ion, a beta-carboline occurring in the human brain.

Journal: Behavioural pharmacology 20060901

Title: Inhibition of neuronal nitric oxide synthase activity by N1-acetyl-5-methoxykynuramine, a brain metabolite of melatonin.

Journal: Journal of neurochemistry 20060901

Title: Partial least squares-based multivariate spectral calibration method for simultaneous determination of beta-carboline derivatives in Peganum harmala seed extracts.

Journal: Analytica chimica acta 20060811

Title: Monoamine oxidase inhibitors allow locomotor and rewarding responses to nicotine.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060801

Title: Neurotoxic mechanisms of 2,9-dimethyl-beta-carbolinium ion in primary dopaminergic culture.

Journal: Journal of neurochemistry 20060801

Title: Effect of nanocavity confinement on the rotational relaxation dynamics: 3-acetyl-4-oxo-6,7-dihydro-12H indolo-[2,3-a] quinolizine in micelles.

Journal: The Journal of chemical physics 20060728

Title: Analysis of monoamine oxidase enzymatic activity by reversed-phase high performance liquid chromatography and inhibition by beta-carboline alkaloids occurring in foods and plants.

Journal: Journal of chromatography. A 20060707

Title: Antidepressant-like effect of harmane and other beta-carbolines in the mouse forced swim test.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20060701

Title: Phytochemical and pharmacological study of roots and leaves of Guiera senegalensis J.F. Gmel (Combretaceae).

Journal: Journal of ethnopharmacology 20060630

Title: Antimalarial activity of a new family of analogues of manzamine A.

Journal: Organic letters 20060608

Title: A selective small molecule IkappaB Kinase beta inhibitor blocks nuclear factor kappaB-mediated inflammatory responses in human fibroblast-like synoviocytes, chondrocytes, and mast cells.

Journal: The Journal of pharmacology and experimental therapeutics 20060601

Title: Identification of norharman as the cytotoxic compound produced by the sponge (Hymeniacidon perleve)-associated marine bacterium Pseudoalteromonas piscicida and its apoptotic effect on cancer cells.

Journal: Biotechnology and applied biochemistry 20060601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Beta-carboline derivatives: novel photosensitizers that intercalate into DNA to cause direct DNA damage in photodynamic therapy.

Journal: Biochemical and biophysical research communications 20060414

Title: Norharman-induced motoric impairment in mice: neurodegeneration and glial activation in substantia nigra.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20060301

Title: In vitro and ex vivo distribution of [3H]harmane, an endogenous beta-carboline, in rat brain.

Journal: Neuropharmacology 20060301

Title: Preparation, structure and spasmolytic activities of some derivatives of harmine series of alkaloids.

Journal: Natural product research 20060301

Title: The alkaloid alstonine: a review of its pharmacological properties.

Journal: Evidence-based complementary and alternative medicine : eCAM 20060301

Title: Effect of chlorine as substituent on the photochemistry and acid-base properties of beta-carboline alkaloids.

Journal: Journal of photochemistry and photobiology. B, Biology 20060201

Title: Human monoamine oxidase enzyme inhibition by coffee and beta-carbolines norharman and harman isolated from coffee.

Journal: Life sciences 20060118

Title: Syntheses of new substituted triazino tetrahydroisoquinolines and beta-carbolines as novel antileishmanial agents.

Journal: European journal of medicinal chemistry 20060101

Title: Antialgal, antibacterial and antifungal activity of two metabolites produced and excreted by cyanobacteria during growth.

Journal: Microbiological research 20060101

Title: 2,9-Dimethyl-beta-carbolinium, a neurotoxin occurring in human brain, is a potent inducer of apoptosis as 1-methyl-4-phenylpyridinium.

Journal: Neuroscience 20060101

Title: Impaired germ cell development due to compromised cell cycle progression in Skp2-deficient mice.

Journal: Cell division 20060101

Title: Toxicity and metabolism of the chloral-derived mammalian alkaloid 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) in PC12 cells.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20060101

Title: DNA binding properties of 9-substituted harmine derivatives.

Journal: Biochemical and biophysical research communications 20051223

Title: beta-Carboline alkaloid suppresses NF-kappaB transcriptional activity through inhibition of IKK signaling pathway.

Journal: Journal of toxicology and environmental health. Part A 20051210

Title: Isolation and chemical characterization of PwTx-II: a novel alkaloid toxin from the venom of the spider Parawixia bistriata (Araneidae, Araneae).

Journal: Toxicon : official journal of the International Society on Toxinology 20051201

Title: The beta-carboline analog Mana-Hox causes mitotic aberration by interacting with DNA.

Journal: Chemistry & biology 20051201

Title: Nostocarboline: isolation and synthesis of a new cholinesterase inhibitor from Nostoc 78-12A.

Journal: Journal of natural products 20051201

Title: Conformationally constrained N1-arylsulfonyltryptamine derivatives as 5-HT6 receptor antagonists.

Journal: Bioorganic & medicinal chemistry letters 20051101

Title: Harmane inhibits serotonergic dorsal raphe neurons in the rat.

Journal: Psychopharmacology 20051101

Title: Isolation of mutagenic beta-carboline derivatives after nitrite treatment of maillard reaction mixtures and analysis of these compounds from foodstuffs and human urine.

Journal: Bioscience, biotechnology, and biochemistry 20051101

Title: Investigation of the separation of heterocyclic aromatic amines by reversed phase ion-pair liquid chromatography coupled with tandem mass spectrometry: the role of ion pair reagents on LC-MS/MS sensitivity.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051025

Title: Design, synthesis and in vitro and in vivo antitumor activities of novel beta-carboline derivatives.

Journal: European journal of medicinal chemistry 20051001

Title: Isolation and characterization of norharmane from Reticulitermes termites (Isoptera: Rhinotermitidae).

Journal: Journal of economic entomology 20051001

Title: Effects of harmaline on anxiety-related behavior in mice.

Journal: Physiology & behavior 20050915

Title: Design, synthesis and bioactivities of TAR RNA targeting beta-carboline derivatives based on Tat-TAR interaction.

Journal: European journal of medicinal chemistry 20050901

Title: High-affinity binding of beta-carbolines to imidazoline I2B receptors and MAO-A in rat tissues: norharman blocks the effect of morphine withdrawal on DOPA/noradrenaline synthesis in the brain.

Journal: European journal of pharmacology 20050822

Title: Tangutorine induces p21 expression and abnormal mitosis in human colon cancer HT-29 cells.

Journal: Biochemical pharmacology 20050715

Title: Photochemistry of the alkaloids eudistomin N (6-bromo-nor-harmane) and eudistomin O (8-bromo-nor-harmane) and other bromo-beta-carbolines.

Journal: Journal of photochemistry and photobiology. B, Biology 20050701

Title: Gesashidine A, a beta-carboline alkaloid with an imidazole ring from a Thorectidae sponge.

Journal: Journal of natural products 20050701

Title: Toxocara canis: search for a potential drug amongst beta-carboline alkaloids--in vitro and mouse studies.

Journal: Experimental parasitology 20050601

Title: Synthesis and evaluation of beta-carbolinium cations as new antimalarial agents based on pi-delocalized lipophilic cation (DLC) hypothesis.

Journal: Chemical & pharmaceutical bulletin 20050601

Title: Alkaloids and aromatics of Cyathobasis fruticulosa (Bunge) Aellen.

Journal: Journal of natural products 20050601

Title: Developmental regulation of beta-carboline-induced inhibition of glycine-evoked responses depends on glycine receptor beta subunit expression.

Journal: Molecular pharmacology 20050501

Title: Characterization of some synthetic Ru and Ir complexes by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Journal: Journal of mass spectrometry : JMS 20050501

Title: Comparison of the Protective Effect of Indole beta-carbolines and R-(-)-deprenyl Against Nitrogen Species-Induced Cell Death in Experimental Culture Model of Parkinson's Disease.

Journal: Journal of clinical neurology (Seoul, Korea) 20050401

Title: In-source and postsource decay in negative-ion matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of neutral oligosaccharides.

Journal: Analytical chemistry 20050315

Title: Encapsulation of norharmane in cyclodextrin: formation of 1:1 and 1:2 inclusion complexes.

Journal: Journal of photochemistry and photobiology. B, Biology 20050301

Title: Synthesis and in vitro cytotoxic evaluation of 1,3-bisubstituted and 1,3,9-trisubstituted beta-carboline derivatives.

Journal: European journal of medicinal chemistry 20050301

Title: Agonistic effects of the beta-carboline DMCM revealed in GABA(A) receptor gamma 2 subunit F77I point-mutated mice.

Journal: Neuropharmacology 20050301

Title: Lack of combination hepatocarcinogenicity of harman, norharman and amitrole when given with NaNO2 in the rat.

Journal: The Journal of toxicological sciences 20050201

Title: Human monoamine oxidase is inhibited by tobacco smoke: beta-carboline alkaloids act as potent and reversible inhibitors.

Journal: Biochemical and biophysical research communications 20050114

Title: Photophysics in motionally constrained bioenvironment: interaction of norharmane with bovine serum albumin.

Journal: Photochemistry and photobiology 20050101

Title: Beta-carbolines induce apoptosis in cultured cerebellar granule neurons via the mitochondrial pathway.

Journal: Neuropharmacology 20050101

Title: Red maca (Lepidium meyenii) reduced prostate size in rats.

Journal: Reproductive biology and endocrinology : RB&E 20050101

Title: Permissive nicotine regulation as a complement to traditional tobacco control.

Journal: BMC public health 20050101

Title: Differential modulation of microglia superoxide anion and thromboxane B2 generation by the marine manzamines.

Journal: BMC pharmacology 20050101

Title: Fluorescence quenching of beta-carboline alkaloids in micellar media. A study to select the adequate surfactant to use in analytical techniques.

Journal: Luminescence : the journal of biological and chemical luminescence 20050101

Title: Beta-carboline and quinoline alkaloids in root cultures and intact plants of Peganum harmala.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20050101

Title: Comprehensive photochemistry and photophysics of land- and marine-based beta-carbolines employing time-resolved emission and flash transient spectroscopy.

Journal: Photochemistry and photobiology 20050101

Title: Addition of various carbohydrates to beef burgers affects the formation of heterocyclic amines during frying.

Journal: Journal of agricultural and food chemistry 20041215

Title: New beta-carboline alkaloids from the Andaman Sea sponge Dragmacidon sp.

Journal: Journal of natural products 20041201

Title: Relative exposure to beta-carbolines norharman and harman from foods and tobacco smoke.

Journal: Food additives and contaminants 20041101

Title: The putative imidazoline receptor agonist, harmane, promotes intracellular calcium mobilisation in pancreatic beta-cells.

Journal: European journal of pharmacology 20041006

Title: Carcinogenicity of aminophenylnorharman, a possible novel endogenous mutagen, formed from norharman and aniline, in F344 rats.

Journal: Carcinogenesis 20041001

Title: Norharman and alcohol-dependency in male Wistar rats.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20041001

Title: Synthesis, acute toxicities, and antitumor effects of novel 9-substituted beta-carboline derivatives.

Journal: Bioorganic & medicinal chemistry 20040901

Title: Analysis of alpha- and beta-carbolines in mainstream smoke of reference cigarettes by gas chromatography-mass spectrometry.

Journal: Journal of chromatography. A 20040813

Title: Identification of cytochrome P-450s involved in the formation of APNH from norharman with aniline.

Journal: Mutation research 20040808

Title: Antibiotic-mediated release of tumour necrosis factor alpha and norharman in patients with hospital-acquired pneumonia and septic encephalopathy.

Journal: Intensive care medicine 20040801

Title: Synthesis and antimycobacterial activity of some beta-carboline alkaloids.

Journal: Natural product research 20040801

Title: A comparative molecular field analysis of cytotoxic beta-carboline analogs.

Journal: Acta pharmacologica Sinica 20040701

Title: A fast assembly of pentacyclic benz[f]indolo[2,3-a]quinolizidine core by tandem intermolecular formal aza-[3 + 3] cycloaddition/Pictet-Spengler cyclization: a formal synthesis of (+/-)-tangutorine.

Journal: The Journal of organic chemistry 20040625

Title: Synthesis and biological evaluation of novel beta-carboline derivatives as Tat-TAR interaction inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20040621

Title: Characterization of the cytotoxic mechanism of Mana-Hox, an analog of manzamine alkaloids.

Journal: Biochimica et biophysica acta 20040611

Title: Cytotoxic alkaloids from the marine sponge Thorectandra sp.

Journal: Natural product research 20040601

Title: Dopamine transporter-mediated cytotoxicity of beta-carbolinium derivatives related to Parkinson's disease: relationship to transporter-dependent uptake.

Journal: Journal of neurochemistry 20040501

Title: Photophysics of norharmane in micellar environments: a fluorometric study.

Journal: Biophysical chemistry 20040501

Title: Clinical investigations of the therapeutic potential of ayahuasca: rationale and regulatory challenges.

Journal: Pharmacology & therapeutics 20040501

Title: Pi-delocalized beta-carbolinium cations as potential antimalarials.

Journal: Bioorganic & medicinal chemistry letters 20040405

Title: [Synthesis of 1-indole substituted beta-carboline alkaloid and its derivatives and evaluation of their preliminary antitumor activities].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20040401

Title: High-performance liquid chromatographic analysis of beta-carbolines in human scalp hair.

Journal: Journal of chromatography. A 20040326

Title: Occurrence of heterocyclic amines in several home-cooked meat dishes of the Spanish diet.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040325

Title: Exposure to beta-carbolines norharman and harman.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040325

Title: Mutagens formed from beta-carbolines with aromatic amines.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040325

Title: Regulation and biochemistry of mouse molybdo-flavoenzymes. The DBA/2 mouse is selectively deficient in the expression of aldehyde oxidase homologues 1 and 2 and represents a unique source for the purification and characterization of aldehyde oxidase.

Journal: The Journal of biological chemistry 20040305

Title: Long-term retention of neurotoxic beta-carbolines in brain neuromelanin.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20040201

Title: The effects of imidazoline agents on the aggregation of human platelets.

Journal: The Journal of pharmacy and pharmacology 20040201

Title: In vitro activity of the beta-carboline alkaloids harmane, harmine, and harmaline toward parasites of the species Leishmania infantum.

Journal: Experimental parasitology 20040101

Title: Characterization of humic substances by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20040101

Title: A new efficient synthetic methodology for tetrahydroisoquinoline and tetrahydro-beta-carboline derivatives using the Pictet-Spengler reaction.

Journal: Molecular diversity 20040101

Title: Effect of diazepam on the CNS excitation and behavioural changes induced by harmaline and its newly synthesized analogues.

Journal: Pakistan journal of pharmaceutical sciences 20040101

Title: Effects of the beta-carbolines, harmane and pinoline, on insulin secretion from isolated human islets of Langerhans.

Journal: European journal of pharmacology 20031215

Title: Potent genotoxicity of aminophenylnorharman, formed from non-mutagenic norharman and aniline, in the liver of gpt delta transgenic mouse.

Journal: Carcinogenesis 20031201

Title: Craving for cigarettes among low and high dependent smokers: impact of norharman.

Journal: Addiction biology 20031201

Title: Comparative effects of efaroxan and beta-carbolines on the secretory activity of rodent and human beta cells.

Journal: Annals of the New York Academy of Sciences 20031201

Title: Effect of harmane on mononeuropathic pain in rats.

Journal: Annals of the New York Academy of Sciences 20031201

Title: Possibility of the involvement of 9H-pyrido[3,4-b]indole (norharman) in carcinogenesis via inhibition of cytochrome P450-related activities and intercalation to DNA.

Journal: Mutation research 20031110

Title: Influence of antioxidants in virgin olive oil on the formation of heterocyclic amines in fried beefburgers.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20031101

Title: Identification of tryptophan and beta-carboline as paralysins in larvae of the yellow mealworm, Tenebrio molitor.

Journal: Biochemical and biophysical research communications 20031010

Title: Cytotoxic and antimalarial beta-carboline alkaloids from the roots of Eurycoma longifolia.

Journal: Journal of natural products 20031001

Title: Detection and characterization of cyclodextrin complexes with beta-carboline derivatives by spectroscopic techniques.

Journal: Journal of pharmaceutical and biomedical analysis 20030808

Title: Novel IKK inhibitors: beta-carbolines.

Journal: Bioorganic & medicinal chemistry letters 20030721

Title: Photophysical properties of methyl beta-carboline-3-carboxylate mediated by hydrogen-bonded complexes--a comparative study in different solvents.

Journal: Biophysical chemistry 20030701

Title: Screening for endogenous substrates reveals that CYP2D6 is a 5-methoxyindolethylamine O-demethylase.

Journal: Pharmacogenetics 20030601

Title: New manzamine alkaloids with activity against infectious and tropical parasitic diseases from an Indonesian sponge.

Journal: Journal of natural products 20030601

Title: Spectrofluorimetric determination of manzamine A in spiked human urine and plasma.

Journal: Die Pharmazie 20030601

Title: Chemical constituents of Taraxacum formosanum.

Journal: Chemical & pharmaceutical bulletin 20030501

Title: Design, synthesis, and biological evaluation of non-peptidic ligands at the Xenopus laevis skin-melanocortin receptor.

Journal: European journal of medicinal chemistry 20030501

Title: Design, synthesis and biological activity of beta-carboline-based type-5 phosphodiesterase inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20030417

Title: Contribution of individual cytochrome P450 isozymes to the O-demethylation of the psychotropic beta-carboline alkaloids harmaline and harmine.

Journal: The Journal of pharmacology and experimental therapeutics 20030401

Title: Shishijimicins A-C, novel enediyne antitumor antibiotics from the ascidian Didemnum proliferum(1).

Journal: Journal of the American Chemical Society 20030226

Title: Isolation and identification of two [(3)H]norharman- ([(3)H]beta-carboline)-binding proteins from rat liver.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030125

Title: Mechanism-based pharmacokinetic/pharmacodynamic modeling of the electroencephalogram effects of GABAA receptor modulators: in vitro-in vivo correlations.

Journal: The Journal of pharmacology and experimental therapeutics 20030101

Title: Beta-carboline alkaloids from a New Zealand marine bryozoan, Cribricellina cribraria.

Journal: Natural product research 20030101

Title: Tetrahydroisoquinoline and beta-carboline alkaloids from Haloxylon articulatum (Cav.) Bunge (Chenopodiaceae).

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20030101

Title: The role of GABA in the pathophysiology and treatment of anxiety disorders.

Journal: Psychopharmacology bulletin 20030101

Title: Synthesis of beta- and gamma-carbolines by the palladium-catalyzed iminoannulation of alkynes.

Journal: The Journal of organic chemistry 20021227

Title: Elevation of blood beta-carboline alkaloids in essential tremor.

Journal: Neurology 20021224

Title: Rhythmicity without synchrony in the electrically uncoupled inferior olive.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20021215

Title: Effects of ayahuasca on sensory and sensorimotor gating in humans as measured by P50 suppression and prepulse inhibition of the startle reflex, respectively.

Journal: Psychopharmacology 20021201

Title: Determination of N,N-dimethyltryptamine and beta-carboline alkaloids in human plasma following oral administration of Ayahuasca.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20021105

Title: Structure of DNA adduct formed with aminophenylnorharman, being responsible for the comutagenic action of norharman with aniline.

Journal: Chemical research in toxicology 20021001

Title: In vitro and in vivo formation of aminophenylnorharman from norharman and aniline.

Journal: Mutation research 20020930

Title: Synthesis and cytotoxic activity of pyridazino[1',6':1,2]pyrido[3,4-b]indol-5-inium derivatives as anti-cancer agents.

Journal: Bioorganic & medicinal chemistry letters 20020916

Title: Contribution of the alpha1-GABA(A) receptor subtype to the pharmacological actions of benzodiazepine site inverse agonists.

Journal: Neuropharmacology 20020901

Title: High-performance liquid chromatographic, capillary electrophoretic and capillary electrophoretic-electrospray ionisation mass spectrometric analysis of selected alkaloid groups.

Journal: Journal of chromatography. A 20020816

Title: Screening for heterocyclic amines in chicken cooked in various ways.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20020801

Title: The biosynthesis of beta-carboline and quinolizidine alkaloids of Alangium lamarckii.

Journal: Phytochemistry 20020801

Title: 5-hydroxytryptamine-derived alkaloids from two marine sponges of the genus Hyrtios.

Journal: Journal of natural products 20020801

Title: Multistep mass spectrometry of heterocyclic amines in a quadrupole ion trap mass analyser.

Journal: Journal of mass spectrometry : JMS 20020801

Title: Identification and occurrence of the bioactive beta-carbolines norharman and harman in coffee brews.

Journal: Food additives and contaminants 20020801

Title: Tetrahydro-beta-carboline alkaloids that occur in foods and biological systems act as radical scavengers and antioxidants in the ABTS assay.

Journal: Free radical research 20020801

Title: Identification and occurrence of the novel alkaloid pentahydroxypentyl-tetrahydro-beta-carboline-3-carboxylic acid as a tryptophan glycoconjugate in fruit juices and jams.

Journal: Journal of agricultural and food chemistry 20020731

Title: 1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) and related derivatives: chemistry and biochemical effects on catecholamine biosynthesis.

Journal: Bioorganic & medicinal chemistry 20020701

Title: The anti-epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA- and glycine-gated currents.

Journal: British journal of pharmacology 20020701

Title: Thermodynamic study of small hydrophobic ions at the water-lipid interface.

Journal: Journal of colloid and interface science 20020701

Title: Phenylethanolamine N-methyltransferase has beta-carboline 2N-methyltransferase activity: hypothetical relevance to Parkinson's disease.

Journal: Neurochemistry international 20020601

Title: Topographic pharmaco-EEG mapping of the effects of the South American psychoactive beverage ayahuasca in healthy volunteers.

Journal: British journal of clinical pharmacology 20020601

Title: Natural variations of precursors in pig meat affect the yield of heterocyclic amines--effects of RN genotype, feeding regime, and sex.

Journal: Journal of agricultural and food chemistry 20020508

Title: The levels of norharman are high enough after smoking to affect monoamineoxidase B in platelets.

Journal: European journal of pharmacology 20020419

Title: Beta-carbolines as specific inhibitors of cyclin-dependent kinases.

Journal: Bioorganic & medicinal chemistry letters 20020408

Title: [The effect on other individual presentations of the goldfish by FG7142 injection].

Journal: Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20020401

Title: Induction of sister chromatid exchanges and chromosome aberrations in cultured mammalian cells treated with aminophenylnorharman formed by norharman with aniline.

Journal: Mutation research 20020325

Title: Genotoxic and recombinogenic activities of the two beta-carboline alkaloids harman and harmine in Saccharomyces cerevisiae.

Journal: Mutation research 20020320

Title: Characterization of the discriminable stimulus produced by 2-BFI: effects of imidazoline I(2)-site ligands, MAOIs, beta-carbolines, agmatine and ibogaine.

Journal: British journal of pharmacology 20020301

Title: Maternal and developmental toxicity in mice by aminophenylnorharman, formed from norharman and aniline.

Journal: Human & experimental toxicology 20020301

Title: Beta-carboline-carbohydrate hybrids: molecular design, chemical synthesis and evaluation of novel DNA photocleavers.

Journal: Bioorganic & medicinal chemistry letters 20020225

Title: The impact of smoking and drinking on plasma levels of norharman.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20020201

Title: Synergistic in vitro antimalarial activity of plant extracts used as traditional herbal remedies in Mali.

Journal: Parasitology research 20020201

Title: Indole and beta-carboline alkaloids from Geissospermum sericeum.

Journal: Journal of natural products 20020101

Title: An in vitro evaluation of human DNA topoisomerase I inhibition by Peganum harmala L. seeds extract and its beta-carboline alkaloids.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20020101

Title: Interaction of folk medicinal plant extracts with human alpha2-adrenoceptor subtypes.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101

Title: An in vitro study on the kinetics, subcellular distribution and phototoxicity of harmine in human tumor cells.

Journal: Bollettino chimico farmaceutico 20020101

Title: Potential neurotoxic 'agents provocateurs' in Parkinson's disease.

Journal: Neurotoxicology and teratology 20020101

Title: [Serum norharman and harman analysis using high pressure liquid chromatography/mass spectrometry and value of beta-carbolines as blood alcohol markers].

Journal: Archiv fur Kriminologie 20020101

Title: Total syntheses of beta-carboline alkaloids, (R)-(-)-pyridindolol K1, (R)-(-)-pyridindolol K2, and (R)-(-)-pyridindolol.

Journal: The Journal of organic chemistry 20011228

Title: Toxicokinetics of tremorogenic natural products, harmane and harmine, in male Sprague-Dawley rats.

Journal: Journal of toxicology and environmental health. Part A 20011221

Title: Degradation of tetrahydro-beta-carbolines in the presence of nitrite: HPLC-MS analysis of the reaction products.

Journal: Journal of agricultural and food chemistry 20011201

Title: Genotoxic effects of the alkaloids harman and harmine assessed by comet assay and chromosome aberration test in mammalian cells in vitro.

Journal: Pharmacology & toxicology 20011201

Title: New cytotoxic N-methylated beta-carboline alkaloids from the marine ascidian Eudistoma gilboverde.

Journal: Journal of natural products 20011101

Title: beta-carboline binding to imidazoline receptors.

Journal: Drug and alcohol dependence 20011001

Title: Pharmacokinetics of the beta-carboline norharman in man.

Journal: Life sciences 20010921

Title: Testicular toxicity in F344 rats by aminophenylnorharman, formed from norharman and aniline.

Journal: Toxicology and applied pharmacology 20010901

Title: Stimulatory effect of harmane and other beta-carbolines on locus coeruleus neurons in anaesthetized rats.

Journal: Neuroscience letters 20010810

Title: Why are the terpenoid indole alkaloids of type I homochiral?

Journal: Chirality 20010801

Title: Oxidative DNA damage by an N-hydroxy metabolite of the mutagenic compound formed from norharman and aniline.

Journal: Mutation research 20010725

Title: Anti-AIDS agents. 46. Anti-HIV activity of harman, an anti-HIV principle from Symplocos setchuensis, and its derivatives.

Journal: Journal of natural products 20010701

Title: [Synthetic studies of the bioactive natural products by using the thermal electrocyclic reaction of 6 pi electron systems].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20010701

Title: Structures of mutagens produced by the co-mutagen norharman with o- and m-toluidine isomers.

Journal: Mutation research 20010627

Title: The acute effects of norharman on cocaine self-administration and sensorimotor function in male Wistar rats.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20010601

Title: Psychotogenic properties of benzodiazepine receptor inverse agonists.

Journal: Psychopharmacology 20010601

Title: Tryptophan: a precursor for the endogenous synthesis of norharman in man.

Journal: Neuroscience letters 20010511

Title: Reaction of tryptophan with carbohydrates: identification and quantitative determination of novel beta-carboline alkaloids in food.

Journal: Journal of agricultural and food chemistry 20010501

Title: L-Deprenyl prevents the cell hypoxia induced by dopaminergic neurotoxins, MPP(+) and beta-carbolinium: a microdialysis study in rats.

Journal: Neuroscience letters 20010420

Title: Exposure of a 'witness rat' to one treated with beta-carboline FG 7142 does not increase dopamine turnover in the medial prefrontal cortex of the 'witness rat'.

Journal: Neuroscience letters 20010420

Title: Hydrogen bonding NH/pi interactions between betacarboline and methyl benzene derivatives.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20010401

Title: Induction of liver preneoplastic lesions by aminophenylnorharman, formed from norharman and aniline, in male F344 rats.

Journal: Cancer letters 20010226

Title: Synthesis and biological evaluation of DNA targeting flexible side-chain substituted beta-carboline derivatives.

Journal: Bioorganic & medicinal chemistry letters 20010226

Title: Canthin-6-one and beta-carboline alkaloids from Eurycoma harmandiana.

Journal: Phytochemistry 20010201

Title: Cis- and trans-platinum and palladium complexes: a comparative study review as antitumour agents.

Journal: Bollettino chimico farmaceutico 20010101

Title: Norharman, an indoleamine-derived beta-carboline, but not Trp-P-2, a gamma-carboline, induces apoptotic cell death in human neuroblastoma SH-SY5Y cells.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20010101

Title: Effects of beta- and gamma-carboline derivatives of DNA topoisomerase activities.

Journal: Mutation research 19960201

Title: ELISA of pentosidine, an advanced glycation end product, in biological specimens.

Journal: Clinical chemistry 19940901

Title: Inhibition of indoleamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase by beta-carboline and indole derivatives.

Journal: Archives of biochemistry and biophysics 19840801

Title: Herraiz T, et al. Human monoamine oxidase enzyme inhibition by coffee and beta-carbolines norharman and harman isolated from coffee. Life Sci. 2006 Jan 18;78(8):795-802.

Title: López-González D, et al. A natural indole alkaloid, norharmane, affects PIN expression patterns and compromises root growth in Arabidopsis thaliana. Plant Physiol Biochem. 2020 Jun;151:378-390.

Title: Ebrahimi-Ghiri M, et al. Anxiolytic and antidepressant effects of ACPA and harmaline co-treatment. Behav Brain Res. 2019 May 17;364:296-302.

Title: Saito K, Chen CY, Masana M, Crowley JS, Markey SP, Heyes MP. 4-Chloro-3-hydroxyanthranilate, 6-chlorotryptophan and norharmane attenuate quinolinic acid formation by interferon-gamma-stimulated monocytes (THP-1 cells). Biochem J. 1993 Apr 1;291 ( Pt 1)(Pt 1):11-4.

Title: Paul BK, et al. Binding of norharmane with RNA reveals two thermodynamically different binding modes with opposing heat capacity changes. J Colloid Interface Sci. 2019 Mar 7;538:587-596.

Title: Luo HZ, et al. Inhibitory effect of norharmane on Serratia marcescens NJ01 quorum sensing-mediated virulence factors and biofilm formation. Biofouling. 2021 Feb;37(2):145-160.

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Tags:244-63-3 Molecular Formula|244-63-3 MDL|244-63-3 SMILES|244-63-3 9H-Pyrido[3,4-b]indole |Organic_Building_Blocks