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24425-56-7,MFCD00056735
Catalog No.:AA007N7F

24425-56-7 | S-HEXYLGLUTATHIONE

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100mg
≥95%
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$116.00   $81.00
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250mg
≥95%
in stock  
$242.00   $169.00
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500mg
≥95%
in stock  
$453.00   $317.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA007N7F
Chemical Name:
S-HEXYLGLUTATHIONE
CAS Number:
24425-56-7
Molecular Formula:
C16H29N3O6S
Molecular Weight:
391.4830
MDL Number:
MFCD00056735
SMILES:
CCCCCCSCC(C(=O)NCC(=O)O)NC(=O)CCC(C(=O)O)N
Properties
Computed Properties
 
Complexity:
475  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
15  
XLogP3:
-1.8  

Literature

Title: GST pi modulates JNK activity through a direct interaction with JNK substrate, ATF2.

Journal: Protein science : a publication of the Protein Society 20110501

Title: Role of gamma-glutamyl transpeptidase in redox regulation of K+ channel remodeling in postmyocardial infarction rat hearts.

Journal: American journal of physiology. Cell physiology 20090801

Title: Modulating catalytic activity by unnatural amino acid residues in a GSH-binding loop of GST P1-1.

Journal: Journal of molecular biology 20080222

Title: Probing the mechanism of GSH activation in Schistosoma haematobium glutathione-S-transferase by site-directed mutagenesis and X-ray crystallography.

Journal: Journal of molecular biology 20060714

Title: Nitric oxide-mediated effect of nipradilol, an alpha- and beta-adrenergic blocker, on glutamate neurotoxicity in rat cortical cultures.

Journal: European journal of pharmacology 20060327

Title: Plasmodium falciparum glutathione S-transferase--structural and mechanistic studies on ligand binding and enzyme inhibition.

Journal: Protein science : a publication of the Protein Society 20060201

Title: Structural basis of the suppressed catalytic activity of wild-type human glutathione transferase T1-1 compared to its W234R mutant.

Journal: Journal of molecular biology 20060106

Title: Tertiary interactions stabilise the C-terminal region of human glutathione transferase A1-1: a crystallographic and calorimetric study.

Journal: Journal of molecular biology 20050617

Title: Structure of the major cytosolic glutathione S-transferase from the parasitic nematode Onchocerca volvulus.

Journal: The Journal of biological chemistry 20050401

Title: Crystallographic and thermodynamic analysis of the binding of S-octylglutathione to the Tyr 7 to Phe mutant of glutathione S-transferase from Schistosoma japonicum.

Journal: Biochemistry 20050201

Title: Native and inhibited structure of a Mu class-related glutathione S-transferase from Plasmodium falciparum.

Journal: The Journal of biological chemistry 20040109

Title: Structure of an insect delta-class glutathione S-transferase from a DDT-resistant strain of the malaria vector Anopheles gambiae.

Journal: Acta crystallographica. Section D, Biological crystallography 20031201

Title: Thermodynamic description of the effect of the mutation Y49F on human glutathione transferase P1-1 in binding with glutathione and the inhibitor S-hexylglutathione.

Journal: The Journal of biological chemistry 20031121

Title: The anomalous pKa of Tyr-9 in glutathione S-transferase A1-1 catalyzes product release.

Journal: The Journal of biological chemistry 20030523

Title: Characterization of the electrophile binding site and substrate binding mode of the 26-kDa glutathione S-transferase from Schistosoma japonicum.

Journal: Proteins 20030401

Title: 1.3-A resolution structure of human glutathione S-transferase with S-hexyl glutathione bound reveals possible extended ligandin binding site.

Journal: Proteins 20020901

Title: Role of GST P1-1 in mediating the effect of etoposide on human neuroblastoma cell line Sh-Sy5y.

Journal: Journal of cellular biochemistry 20020101

Title: Crystal structures of the yeast prion Ure2p functional region in complex with glutathione and related compounds.

Journal: Biochemistry 20011113

Title: Purification and characterization of a glutathione S-transferase Omega in pig: evidence for two distinct organ-specific transcripts.

Journal: The Biochemical journal 20010815

Title: An alternative pathway for metabolism of leukotriene D(4): effects on contractions to cysteinyl-leukotrienes in the guinea-pig trachea.

Journal: British journal of pharmacology 20010801

Title: Functional residues on the enzyme active site of glyoxalase I from bovine brain.

Journal: Preparative biochemistry & biotechnology 20010801

Title: 3-Methyleneoxindole: an affinity label of glutathione S-transferase pi which targets tryptophan 38.

Journal: Biochemistry 20010626

Title: Coumarin and chromen-4-one analogues as tautomerase inhibitors of macrophage migration inhibitory factor: discovery and X-ray crystallography.

Journal: Journal of medicinal chemistry 20010215

Title: Ligand-induced changes in the structure and dynamics of a human class Mu glutathione S-transferase.

Journal: Biochemistry 20000627

Title: The three-dimensional structure of an avian class-mu glutathione S-transferase, cGSTM1-1 at 1.94 A resolution.

Journal: Journal of molecular biology 19980424

Title: Interaction of glutathione transferase P1-1 with captan and captafol.

Journal: Biochemical pharmacology 19960712

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Tags:24425-56-7 Molecular Formula|24425-56-7 MDL|24425-56-7 SMILES|24425-56-7 S-HEXYLGLUTATHIONE