Catalog No.:AA002ONT

24603-63-2 | 5-Chlorobenzo[d]isoxazol-3-ol

Name: Name:5-Chlorobenzo[d]isoxazol-3-ol
Brand: AABLOCKS
SKU: AA002ONT
Availability: InStock
Rating: 90 (10 reviews)

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Purity

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Price(USD)

Quantity

250mg

95%

in stock

$160.00 $112.00

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Technical Information
Properties
Downstream Synthesis Route
Literature
Request for Quotation
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Technical Information
Properties
Downstream Synthesis Route
Literature

Technical Information

Catalog Number:

AA002ONT

Chemical Name:

5-Chlorobenzo[d]isoxazol-3-ol

CAS Number:

24603-63-2

Molecular Formula:

C7H4ClNO2

Molecular Weight:

169.5652

MDL Number:

MFCD00125031

SMILES:

Clc1ccc2c(c1)c(=O)[nH]o2

Properties

BP:

336.7°C at 760 mmHg

Form:

Solid

MP:

216-220 °C

Storage:

Keep in dry area;2-8℃;

Computed Properties

Complexity:

185

Covalently-Bonded Unit Count:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

XLogP3:

1.8

Downstream Synthesis Route

37551-43-2

24603-63-2

[1]JournalofHeterocyclicChemistry,1979,vol.16,p.1277-1278

16263-53-9

24603-63-2

[1]ChemischeBerichte,1967,vol.100,p.3326-3330

24603-63-2

16263-53-9

[1]Patent:US5965591,1999,A

[2]ChemischeBerichte,1967,vol.100,p.3326-3330

37551-43-2

24603-63-2

[1]JournalofMedicinalChemistry,1986,vol.29,p.359-369

24603-63-2

16263-53-9

[1]JournalofMedicinalChemistry,1986,vol.29,p.359-369

Literature

Title: Pharmacokinetics of oral D-serine in D-amino acid oxidase knockout mice.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20121101

Title: Contributions of spinal D-amino acid oxidase to bone cancer pain.

Journal: Amino acids 20121101

Title: Interactions of the potent D-amino acid oxidase inhibitor CBIO with morphine in pain and tolerance to analgesia.

Journal: Neuropharmacology 20120901

Title: D-Amino acid oxidase-mediated increase in spinal hydrogen peroxide is mainly responsible for formalin-induced tonic pain.

Journal: British journal of pharmacology 20120301

Title: A series of D-amino acid oxidase inhibitors specifically prevents and reverses formalin-induced tonic pain in rats.

Journal: The Journal of pharmacology and experimental therapeutics 20110101

Title: Beyond the dopamine receptor: novel therapeutic targets for treating schizophrenia.

Journal: Dialogues in clinical neuroscience 20100901

Title: Commentary: genome-based CNS drug discovery: D-amino acid oxidase (DAAO) as a novel target for antipsychotic medications: progress and challenges.

Journal: Biochemical pharmacology 20091201

Title: Co-administration of a D-amino acid oxidase inhibitor potentiates the efficacy of D-serine in attenuating prepulse inhibition deficits after administration of dizocilpine.

Journal: Biological psychiatry 20090615

Title: Synthesis and biological evaluation of D-amino acid oxidase inhibitors.

Journal: Journal of medicinal chemistry 20080626

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