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26703-03-7,MFCD00005149
Catalog No.:AA01X38M

26703-03-7 | Oxirane, 2-ethenyl-, homopolymer

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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01X38M
Chemical Name:
Oxirane, 2-ethenyl-, homopolymer
CAS Number:
26703-03-7
Molecular Formula:
C4H6O
Molecular Weight:
70.0898
MDL Number:
MFCD00005149
SMILES:
C=CC1CO1
UN Number:
1993
Properties
Computed Properties
 
Complexity:
49.6  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
5  
Hydrogen Bond Acceptor Count:
1  
Rotatable Bond Count:
1  
Undefined Atom Stereocenter Count:
1  
XLogP3:
0.5  

Literature

Title: Inhibitory potency of 4-carbon alkanes and alkenes toward CYP2E1 activity.

Journal: Toxicology 20140406

Title: DNA damage induced by three major metabolites of 1,3-butadiene in human hepatocyte L02 cells.

Journal: Mutation research 20120918

Title: A mechanistic modeling framework for predicting metabolic interactions in complex mixtures.

Journal: Environmental health perspectives 20111201

Title: Kinetics of ethylene and ethylene oxide in subcellular fractions of lungs and livers of male B6C3F1 mice and male fischer 344 rats and of human livers.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20111001

Title: Quantitative analysis of trihydroxybutyl mercapturic acid, a urinary metabolite of 1,3-butadiene, in humans.

Journal: Chemical research in toxicology 20110919

Title: 1,3-Butadiene: Biomarkers and application to risk assessment.

Journal: Chemico-biological interactions 20110630

Title: Stereoselective coupling reaction of dimethylzinc and alkyne toward nickelacycles.

Journal: Organic letters 20110506

Title: 1,3-Butadiene: II. Genotoxicity profile.

Journal: Critical reviews in toxicology 20101001

Title: Exposure-response of 1,2:3,4-diepoxybutane-specific N-terminal valine adducts in mice and rats after inhalation exposure to 1,3-butadiene.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100601

Title: Mutagenicity of stereochemical configurations of 1,3-butadiene epoxy metabolites in human cells.

Journal: Research report (Health Effects Institute) 20100601

Title: Quantitative investigation on the metabolism of 1,3-butadiene and of its oxidized metabolites in once-through perfused livers of mice and rats.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100301

Title: Stereoselective ring expansion of vinyl oxiranes: mechanistic insights and natural product total synthesis.

Journal: Angewandte Chemie (International ed. in English) 20100222

Title: Cob(I)alamin for trapping butadiene epoxides in metabolism with rat S9 and for determining associated kinetic parameters.

Journal: Chemical research in toxicology 20090901

Title: Genotoxicity of 1,3-butadiene and its epoxy intermediates.

Journal: Research report (Health Effects Institute) 20090801

Title: Investigation on the mechanisms of genotoxicity of butadiene, styrene and their combination in human lymphocytes using the Comet assay.

Journal: Mutation research 20090512

Title: Alternative reagents for chemical noise reduction in liquid chromatography-mass spectrometry using selective ion-molecule reactions.

Journal: Journal of the American Society for Mass Spectrometry 20090101

Title: An efficient and general enantioselective synthesis of sphingosine, phythosphingosine, and 4-substituted derivatives.

Journal: Organic letters 20090101

Title: Evaluation of cancer tests of 1,3-butadiene using internal dose, genotoxic potency, and a multiplicative risk model.

Journal: Cancer research 20081001

Title: Bimetallic dendrimer-encapsulated nanoparticles as catalysts: a review of the research advances.

Journal: Chemical Society reviews 20080801

Title: HPRT mutations in lymphocytes from 1,3-butadiene-exposed workers in China.

Journal: Environmental health perspectives 20080201

Title: Catalytic performance of symmetrical and unsymmetrical sulfur-containing pincer complexes: synthesis and tandem catalytic activity of the first PCS-pincer palladium complex.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

Title: Development of a physiologically based toxicokinetic model for butadiene and four major metabolites in humans: global sensitivity analysis for experimental design issues.

Journal: Chemico-biological interactions 20070501

Title: Metabolism of 1,3-butadiene to toxicologically relevant metabolites in single-exposed mice and rats.

Journal: Chemico-biological interactions 20070320

Title: Some insights into the mode of action of butadiene by examining the genotoxicity of its metabolites.

Journal: Chemico-biological interactions 20070320

Title: Synthesis of DNA oligodeoxynucleotides containing structurally defined N6-(2-hydroxy-3-buten-1-yl)-adenine adducts of 3,4-epoxy-1-butene.

Journal: Chemico-biological interactions 20070320

Title: Mutagenicity of stereochemical configurations of 1,2-epoxybutene and 1,2:3,4-diepoxybutane in human lymphblastoid cells.

Journal: Chemico-biological interactions 20070320

Title: Quantitative analysis of N-terminal valine peptide adducts specific for 1,2-epoxy-3-butene.

Journal: Chemico-biological interactions 20070320

Title: N-terminal globin adducts as biomarkers for formation of butadiene derived epoxides.

Journal: Chemico-biological interactions 20070320

Title: Identification of covalent modifications in P450 2E1 by 1,2-epoxy-3-butene in vitro.

Journal: Chemico-biological interactions 20070320

Title: Copper-catalyzed rearrangement of vinyl oxiranes.

Journal: Journal of the American Chemical Society 20061220

Title: Palladium-catalyzed DYKAT of butadiene monoepoxide: enantioselective total synthesis of (+)-DMDP, (-)-bulgecinine, and (+)-broussonetine G.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20060825

Title: 3,4-Epoxy-1-butene, a reactive metabolite of 1,3-butadiene, induces somatic mutations in Xpc-null mice.

Journal: Environmental and molecular mutagenesis 20060101

Title: Cellular analysis of disorazole C and structure-activity relationship of analogs of the natural product.

Journal: Chemical biology & drug design 20060101

Title: Hemoglobin adducts and micronuclei in rodents after treatment with isoprene monoxide or butadiene monoxide.

Journal: Mutation research 20050801

Title: Structure of an oligodeoxynucleotide containing a butadiene oxide-derived N1 beta-hydroxyalkyl deoxyinosine adduct in the human N-ras codon 61 sequence.

Journal: Biochemistry 20050308

Title: Regio- and stereoselectivity of the addition of O-, S-, N-, and C-nucleophiles to the beta vinyl oxirane derived from D-glucal.

Journal: The Journal of organic chemistry 20041210

Title: Effects of 1,3-butadiene, isoprene, and their photochemical degradation products on human lung cells.

Journal: Environmental health perspectives 20041101

Title: Stereospecific uncatalyzed alpha-O-glycosylation and alpha-C-glycosidation by means of a new D-Gulal-derived alpha vinyl oxirane.

Journal: The Journal of organic chemistry 20041015

Title: Synthesis of chiral phosphoantigens and their activity in gamma delta T cell stimulation.

Journal: Bioorganic & medicinal chemistry letters 20040906

Title: DNA adducts in rats and mice following exposure to [4-14C]-1,2-epoxy-3-butene and to [2,3-14C]-1,3-butadiene.

Journal: Chemico-biological interactions 20040630

Title: Characterization of alkyl-cobalamins formed on trapping of epoxide metabolites of 1,3-butadiene.

Journal: Journal of separation science 20040501

Title: Dose responses for DNA adduct formation in tissues of rats and mice exposed by inhalation to low concentrations of 1,3-[2,3-[(14)C]-butadiene.

Journal: Chemico-biological interactions 20040315

Title: Dose responses for the formation of hemoglobin adducts and urinary metabolites in rats and mice exposed by inhalation to low concentrations of 1,3-[2,3-(14)C]-butadiene.

Journal: Chemico-biological interactions 20040315

Title: Identification and characterization of a series of nucleoside adducts formed by the reaction of 2'-deoxyguanosine and 1,2,3,4-diepoxybutane under physiological conditions.

Journal: Chemical research in toxicology 20031201

Title: Genetic susceptibility, biomarker respones, and cancer.

Journal: Mutation research 20031101

Title: Mutagenic spectrum of butadiene-derived N1-deoxyinosine adducts and N6,N6-deoxyadenosine intrastrand cross-links in mammalian cells.

Journal: Chemical research in toxicology 20021201

Title: New stereoselective beta-glycosylation via a vinyl oxirane derived from D-glucal.

Journal: Organic letters 20021017

Title: Synthesis and characterization of water-soluble hydroxybutenyl cyclomaltooligosaccharides (cyclodextrins).

Journal: Carbohydrate research 20020315

Title: Enantioselective allylation of beta,gamma-unsaturated aldehydes generated via Lewis acid induced rearrangement of 2-vinyloxiranes.

Journal: Organic letters 20020110

Title: Dose-dependent excretion of unconjugated 3-butene-1,2-diol measured in urine with a gc/ms after 1,3-butadiene exposure.

Journal: Toxicology mechanisms and methods 20020101

Title: Metabolism of butadiene monoxide by freshly isolated hepatocytes from mice and rats: different partitioning between oxidative, hydrolytic, and conjugation pathways.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20010601

Title: Cellular and molecular basis for species, sex and tissue differences in 1,3-butadiene metabolism.

Journal: Chemico-biological interactions 20010601

Title: First-pass metabolism of 1,3-butadiene in once-through perfused livers of rats and mice.

Journal: Chemico-biological interactions 20010601

Title: Physiological modeling of butadiene disposition in mice and rats.

Journal: Chemico-biological interactions 20010601

Title: Development of a preliminary physiologically based toxicokinetic (PBTK) model for 1,3-butadiene risk assessment.

Journal: Chemico-biological interactions 20010601

Title: Mutational spectrum of 1,3-butadiene and metabolites 1,2-epoxybutene and 1,2,3,4-diepoxybutane to assess mutagenic mechanisms.

Journal: Chemico-biological interactions 20010601

Title: Advances in the mass spectrometry of hemoglobin adducts: global analysis of the covalent binding of butadiene monoxide.

Journal: Chemico-biological interactions 20010601

Title: A novel DNA adduct, originating from 1,2-epoxy-3,4-butanediol, is the major DNA adduct after exposure to [2,3-(14)C]-1,3-butadiene,[4-(14)C]-1,2-epoxy-3-butane.

Journal: Chemico-biological interactions 20010601

Title: In vitro genotoxicity testing of (1-chloroethenyl)oxirane, a metabolite of beta-chloroprene.

Journal: Chemico-biological interactions 20010601

Title: Synthesis and characterization of oligodeoxynucleotides containing an N1 beta-hydroxyalkyl adduct of 2'-deoxyinosine.

Journal: Chemical research in toxicology 20010601

Title: Synthesis and characterization of nucleosides and oligonucleotides bearing adducts of butadiene epoxides on adenine n(6) and guanine n(2).

Journal: Chemical research in toxicology 20010401

Title: Lung-specific mutagenicity and mutational spectrum in B6C3F1 lacI transgenic mice following inhalation exposure to 1,2-epoxybutene.

Journal: Mutation research 20010125

Title: Hemoglobin adducts of epoxybutene in workers occupationally exposed to 1,3-butadiene.

Journal: Archives of toxicology 20010101

Title: Reactive metabolites of 1,3-butadiene: DNA and hemoglobin adduct formation and potential roles in carcinogenicity.

Journal: Advances in experimental medicine and biology 20010101

Title: Point mutations induced by 1,2-epoxy-3-butene N1 deoxyinosine adducts.

Journal: Environmental and molecular mutagenesis 20010101

Title: 1,3-Butadiene oxidation by human myeloperoxidase. Role of chloride ion in catalysis of divergent pathways.

Journal: The Journal of biological chemistry 19921005

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