Title: Hepatotoxicity of piperazine designer drugs: up-regulation of key enzymes of cholesterol and lipid biosynthesis.
Journal: Archives of toxicology 20161201
Title: Structure-dependent inhibition of the human α1β2γ2 GABAA receptor by piperazine derivatives: A novel mode of action.
Journal: Neurotoxicology 20151201
Title: Estrogenic effects and their action mechanism of the major active components of party pill drugs.
Journal: Toxicology letters 20121115
Title: Enhanced electron transfer dissociation of peptides modified at C-terminus with fixed charges.
Journal: Journal of the American Society for Mass Spectrometry 20121101
Title: Ultra high performance liquid chromatography-electrospray ionization-tandem mass spectrometry screening method for direct analysis of designer drugs, 'spice' and stimulants in oral fluid.
Journal: Journal of chromatography. A 20121005
Title: Limited use of novel psychoactive substances in South London nightclubs.
Journal: QJM : monthly journal of the Association of Physicians 20121001
Title: Novel psychoactive substances: how to understand the acute toxicity associated with the use of these substances.
Journal: Therapeutic drug monitoring 20120801
Title: Piperazine compounds as drugs of abuse.
Journal: Drug and alcohol dependence 20120501
Title: Linking the pharmacological content of ecstasy tablets to the subjective experiences of drug users.
Journal: Psychopharmacology 20120401
Title: Determination of piperazine-type stimulants in human urine by means of microextraction in packed sorbent and high performance liquid chromatography-diode array detection.
Journal: Journal of pharmaceutical and biomedical analysis 20120305
Title: 4-Benzyl-N-methyl-piperazine-1-carbothio-amide.
Journal: Acta crystallographica. Section E, Structure reports online 20120301
Title: Nephrotoxicity of recreational party drugs.
Journal: Nephrology (Carlton, Vic.) 20120201
Title: 3-(Adamantan-1-yl)-1-[(4-benzyl-piperazin-1-yl)meth-yl]-4-phenyl-1H-1,2,4-triazole-5(4H)-thione.
Journal: Acta crystallographica. Section E, Structure reports online 20120201
Title: Rapid determination of piperazine-type stimulants in human urine by microextraction in packed sorbent after method optimization using a multivariate approach.
Journal: Journal of chromatography. A 20120127
Title: Microcrystalline identification of selected designer drugs.
Journal: Forensic science international 20120110
Title: Simultaneous determination of N-benzylpiperazine and 1-(3-trifluoromethylphenyl)piperazine in rat plasma by HPLC-fluorescence detection and its application to monitoring of these drugs.
Journal: Biomedical chromatography : BMC 20120101
Title: Searching for novel anti-myotonic agents: pharmacophore requirement for use-dependent block of skeletal muscle sodium channels by N-benzylated cyclic derivatives of tocainide.
Journal: Neuromuscular disorders : NMD 20120101
Title: Quantitative analysis of hair samples for 1-benzylpiperazine (BZP) using high-performance liquid chromatography triple quadrupole mass spectrometry (LC-MS/MS) detection.
Journal: Analytical and bioanalytical chemistry 20111001
Title: Clinical toxicology of newer recreational drugs.
Journal: Clinical toxicology (Philadelphia, Pa.) 20111001
Title: Subjective effects in humans following administration of party pill drugs BZP and TFMPP alone and in combination.
Journal: Drug testing and analysis 20110901
Title: An analysis of legal highs: do they contain what it says on the tin?
Journal: Drug testing and analysis 20110901
Title: N-centered odd-electron ions formation from collision-induced dissociation of electrospray ionization generated even-electron ions: single electron transfer via ion/neutral complex in the fragmentation of protonated N,N'-dibenzylpiperazines and protonated N-benzylpiperazines.
Journal: Journal of the American Society for Mass Spectrometry 20110901
Title: Synthesis, structure and biological activity of novel 1,2,4-triazole mannich bases containing a substituted benzylpiperazine moiety.
Journal: Chemical biology & drug design 20110701
Title: Poison in party pills is too much to swallow.
Journal: Nature 20110615
Title: Synthesis and biological evaluation of novel 4-benzylpiperazine ligands for sigma-1 receptor imaging.
Journal: Bioorganic & medicinal chemistry 20110501
Title: A new mixed mode solid phase extraction strategy for opioids, cocaines, amphetamines and adulterants in human blood with hybrid liquid chromatography tandem mass spectrometry detection.
Journal: Journal of pharmaceutical and biomedical analysis 20110405
Title: Clinical pattern of toxicity associated with the novel synthetic cathinone mephedrone.
Journal: Emergency medicine journal : EMJ 20110401
Title: Determining the subjective and physiological effects of BZP combined with TFMPP in human males.
Journal: Psychopharmacology 20110401
Title: BZP-party pills: a review of research on benzylpiperazine as a recreational drug.
Journal: The International journal on drug policy 20110301
Title: The clinical toxicology of the designer 'party pills' benzylpiperazine and trifluoromethylphenylpiperazine.
Journal: Clinical toxicology (Philadelphia, Pa.) 20110301
Title: 2-Chloro-1-[4-(2-fluoro-benz-yl)piperazin-1-yl]ethanone.
Journal: Acta crystallographica. Section E, Structure reports online 20110301
Title: Effects of trifluoromethylphenylpiperazine (TFMPP) on interhemispheric communication.
Journal: Psychopharmacology 20110201
Title: Benzylpiperazine: the New Zealand legal perspective.
Journal: Drug testing and analysis 20110101
Title: BZP and New Zealand's alternative approach to prohibition. [An interview with Matt Bowden by Paul Trevorrow].
Journal: Drug testing and analysis 20110101
Title: Development of a rapid LC-MS/MS method for direct urinalysis of designer drugs.
Journal: Drug testing and analysis 20110101
Title: Current awareness of piperazines: pharmacology and toxicology.
Journal: Drug testing and analysis 20110101
Title: Another bitter pill: a case of toxicity from DMAA party pills.
Journal: The New Zealand medical journal 20101217
Title: Novel alkyl- and arylcarbamate derivatives with N-benzylpiperidine and N-benzylpiperazine moieties as cholinesterases inhibitors.
Journal: European journal of medicinal chemistry 20101201
Title: Trazodone, meta-chlorophenylpiperazine (an hallucinogenic drug and trazodone metabolite), and the hallucinogen trifluoromethylphenylpiperazine cross-react with the EMIT®II ecstasy immunoassay in urine.
Journal: Journal of analytical toxicology 20101101
Title: A hybrid liquid chromatography-mass spectrometry strategy in a forensic laboratory for opioid, cocaine and amphetamine classes in human urine using a hybrid linear ion trap-triple quadrupole mass spectrometer.
Journal: Journal of chromatography. A 20101029
Title: Detection of 1-benzylpiperazine, 1-(3-trifluoromethylphenyl)-piperazine, and 1-(3-chlorophenyl)-piperazine in 3,4-methylenedioxymethamphetamine-positive urine samples.
Journal: Journal of analytical toxicology 20101001
Title: Randomised double-blind, placebo-controlled trial of the effects of the 'party pills' BZP/TFMPP alone and in combination with alcohol.
Journal: Journal of psychopharmacology (Oxford, England) 20100901
Title: Validation of an LC-MS method for the detection and quantification of BZP and TFMPP and their hydroxylated metabolites in human plasma and its application to the pharmacokinetic study of TFMPP in humans.
Journal: Journal of forensic sciences 20100901
Title: Imidazo[4,5-b]pyridine derivatives as inhibitors of Aurora kinases: lead optimization studies toward the identification of an orally bioavailable preclinical development candidate.
Journal: Journal of medicinal chemistry 20100722
Title: Purchasing 'legal highs' on the Internet--is there consistency in what you get?
Journal: QJM : monthly journal of the Association of Physicians 20100701
Title: Qualitative drug analysis of hair extracts by comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry.
Journal: Journal of chromatography. A 20100625
Title: Hydride transfer reactions via ion-neutral complex: fragmentation of protonated N-benzylpiperidines and protonated N-benzylpiperazines in mass spectrometry.
Journal: Journal of mass spectrometry : JMS 20100501
Title: Head shop compound abuse amongst attendees of the Drug Treatment Centre Board.
Journal: Irish medical journal 20100501
Title: Multiorgan failure from 1-benzylpiperazine ingestion--legal high or lethal high?
Journal: Clinical toxicology (Philadelphia, Pa.) 20100301
Title: 'They're legal so they're safe, right?' What did the legal status of BZP-party pills mean to young people in New Zealand?
Journal: The International journal on drug policy 20100101
Title: Differences in harm from legal BZP/TFMPP party pills between North Island and South Island users in New Zealand: a case of effective industry self-regulation?
Journal: The International journal on drug policy 20100101
Title: New benzofuran derivatives as an antioxidant agent.
Journal: Indian journal of pharmaceutical sciences 20100101
Title: Legal highs toxicity--symptomatology and clinical diagnosis in case series.
Journal: Przeglad lekarski 20100101
Title: Determining the subjective and physiological effects of BZP on human females.
Journal: Psychopharmacology 20091201
Title: In vivo interactions between BZP and TFMPP (party pill drugs).
Journal: The New Zealand medical journal 20090925
Title: Metabolic interactions with piperazine-based 'party pill' drugs.
Journal: The Journal of pharmacy and pharmacology 20090701
Title: 1-benzylpiperazine (BZP) abuse amongst attendees of the Drug Treatment Centre Board.
Journal: Irish medical journal 20090601
Title: Structure elucidation of a new designer benzylpiperazine: 4-bromo-2,5-dimethoxybenzylpiperazine.
Journal: Forensic science international 20090530
Title: Party pills and drug-drug interactions.
Journal: The New Zealand medical journal 20090424
Title: Pharmacokinetics of 'party pill' drug N-benzylpiperazine (BZP) in healthy human participants.
Journal: Forensic science international 20090415
Title: A comparison of 1-benzylpiperazine and methamphetamine in their acute effects on anxiety-related behavior of hooded rats.
Journal: Pharmacology, biochemistry, and behavior 20090401
Title: Selective suppression of cocaine- versus food-maintained responding by monoamine releasers in rhesus monkeys: benzylpiperazine, (+)phenmetrazine, and 4-benzylpiperidine.
Journal: The Journal of pharmacology and experimental therapeutics 20090401
Title: Synthesis, optimization and structure-activity relationships of 3,5-disubstituted isoxazolines as new anti-tuberculosis agents.
Journal: European journal of medicinal chemistry 20090201
Title: [Speed drugs].
Journal: Przeglad lekarski 20090101
Title: Dissociative and sympathomimetic toxicity associated with recreational use of 1-(3-trifluoromethylphenyl) piperazine (TFMPP) and 1-benzylpiperzine (BZP).
Journal: Journal of medical toxicology : official journal of the American College of Medical Toxicology 20081201
Title: Toxicity from the recreational use of 1-benzylpiperazine.
Journal: Clinical toxicology (Philadelphia, Pa.) 20081101
Title: Patterns of benzylpiperazine/trifluoromethylphenylpiperazine party pill use and adverse effects in a population sample in New Zealand.
Journal: Drug and alcohol review 20081101
Title: Partying on? Life after BZP-based party pills.
Journal: The New Zealand medical journal 20081003
Title: Copper(I) cyanide networks: synthesis, structure, and luminescence behavior. Part 2. Piperazine ligands and hexamethylenetetramine.
Journal: Inorganic chemistry 20080804
Title: 2-[2-(4-Benzyl-piperazin-1-ylcarbon-yl)eth-yl]-5,6-diphenyl-pyridazin-3(2H)-one.
Journal: Acta crystallographica. Section E, Structure reports online 20080601
Title: Investigation of the first deaths in the United Kingdom involving the detection and quantitation of the piperazines BZP and 3-TFMPP.
Journal: Journal of analytical toxicology 20080301
Title: [1-benzylpiperazine (BZP) and 1-(3-trifluorométhylphényl)pipérazine (TFMPP): emergence of two agents which lead to misuse].
Journal: Annales pharmaceutiques francaises 20080301
Title: 1-Benzhydryl-4-(4-chloro-phenyl-sulfonyl)piperazine.
Journal: Acta crystallographica. Section E, Structure reports online 20080201
Title: Detection of 1-benzylpiperazine and 1-(3-trifluoromethylphenyl)-piperazine in urine analysis specimens using GC-MS and LC-ESI-MS.
Journal: Journal of analytical toxicology 20080101
Title: N-benzylpiperazine has characteristics of a drug of abuse.
Journal: Behavioural pharmacology 20071201
Title: Benzylpiperazine: a drug of abuse?
Journal: Journal of psychopharmacology (Oxford, England) 20071101
Title: MDMA-like behavioral effects of N-substituted piperazines in the mouse.
Journal: Pharmacology, biochemistry, and behavior 20071101
Title: Seizures in a night club.
Journal: Lancet (London, England) 20070721
Title: Chronic benzylpiperazine (BZP) exposure produces behavioral sensitization and cross-sensitization to methamphetamine (MA).
Journal: Drug and alcohol dependence 20070511
Title: Piperazine designer drugs of abuse.
Journal: Lancet (London, England) 20070428
Title: Collapse, reported seizure--and an unexpected pill.
Journal: Lancet (London, England) 20070428
Title: Party on? BZP party pills in New Zealand.
Journal: The New Zealand medical journal 20070216
Title: Nitrofurans as novel anti-tuberculosis agents: identification, development and evaluation.
Journal: Current topics in medicinal chemistry 20070101
Title: Highs and lows: patterns of use, positive and negative effects of benzylpiperazine-containing party pills (BZP-party pills) amongst young people in New Zealand.
Journal: Harm reduction journal 20070101
Title: Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy.
Journal: Nature chemical biology 20061001
Title: A new synthesis of sulfonamides by aminolysis of p-nitrophenylsulfonates yielding potent and selective adenosine A2B receptor antagonists.
Journal: Journal of medicinal chemistry 20060713
Title: Identification of new diamine scaffolds with activity against Mycobacterium tuberculosis.
Journal: Journal of medicinal chemistry 20060601
Title: Nephrotoxicity of BZP-based herbal party pills: a New Zealand case report.
Journal: The New Zealand medical journal 20060505
Title: Rewarding properties of 1-benzylpiperazine, a new drug of abuse, in rats.
Journal: Basic & clinical pharmacology & toxicology 20060401
Title: Metabolism and the urinary excretion profile of the recently scheduled designer drug N-Benzylpiperazine (BZP) in the rat.
Journal: Journal of analytical toxicology 20060101
Title: Treatment of adolescent rats with 1-benzylpiperazine: a preliminary study of subsequent behavioral effects.
Journal: Neurotoxicology and teratology 20060101
Title: Toxic effects of BZP-based herbal party pills in humans: a prospective study in Christchurch, New Zealand.
Journal: The New Zealand medical journal 20051216
Title: Inhibition of acetylcholinesterase by the anticancer prodrug CPT-11.
Journal: Chemico-biological interactions 20051215
Title: Researching the toxicity of party pills.
Journal: Nursing New Zealand (Wellington, N.Z. : 1995) 20051201
Title: Metabolism of designer drugs of abuse.
Journal: Current drug metabolism 20050601
Title: Development of simultaneous gas chromatography-mass spectrometric and liquid chromatography-electrospray ionization mass spectrometric determination method for the new designer drugs, N-benzylpiperazine (BZP), 1-(3-trifluoromethylphenyl)piperazine (TFMPP) and their main metabolites in urine.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050525
Title: N-substituted piperazines abused by humans mimic the molecular mechanism of 3,4-methylenedioxymethamphetamine (MDMA, or 'Ecstasy').
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050301
Title: Simultaneous separation of different types of amphetamine and piperazine designer drugs by capillary electrophoresis with a chiral selector.
Journal: Journal of forensic sciences 20050301
Title: Reinforcing and discriminative stimulus effects of 1-benzylpiperazine and trifluoromethylphenylpiperazine in rhesus monkeys.
Journal: Drug and alcohol dependence 20050214
Title: Application of direct urine LC-MS-MS analysis for screening of novel substances in drug abusers.
Journal: Journal of analytical toxicology 20050101
Title: Acute psychosis following ingestion of 'Rapture'.
Journal: Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists 20041201
Title: Schedules of controlled substances; placement of 2,5-dimethoxy-4-(n)-propylthiophenethylamine and N-benzylpiperazine into Schedule I of the Controlled Substances Act. Final rule.
Journal: Federal register 20040318
Title: Multicomponent screening for drugs of abuse: direct analysis of urine by LC-MS-MS.
Journal: Therapeutic drug monitoring 20040201
Title: A2 (N-benzylpiperazine) a new drug of abuse in Sweden.
Journal: Journal of analytical toxicology 20040101
Title: Common drugs of abuse--Part II.
Journal: The Journal of practical nursing 20040101
Title: Activation of a camptothecin prodrug by specific carboxylesterases as predicted by quantitative structure-activity relationship and molecular docking studies.
Journal: Molecular cancer therapeutics 20031101
Title: Screening for and validated quantification of amphetamines and of amphetamine- and piperazine-derived designer drugs in human blood plasma by gas chromatography/mass spectrometry.
Journal: Journal of mass spectrometry : JMS 20030601
Title: Studies on the metabolism and toxicological detection of the new designer drug N-benzylpiperazine in urine using gas chromatography-mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020615
Title: Piperazine-like compounds: a new group of designer drugs-of-abuse on the European market.
Journal: Forensic science international 20010915
Title: [Fatal brain edema after ingestion of ecstasy and benzylpiperazine].
Journal: Deutsche medizinische Wochenschrift (1946) 20010713
Title: Piperazinyl benzamidines: synthesis and affinity for the delta opioid receptor.
Journal: Bioorganic & medicinal chemistry letters 20010709
