Title: 7-Azabicyclo[2.2.1]heptane as a scaffold for the development of selective sigma-2 (σ2) receptor ligands.
Journal: Bioorganic & medicinal chemistry letters 20120615
Title: Synthesis and binding affinity at α4β2 and α7 nicotinic acetylcholine receptors of new analogs of epibatidine and epiboxidine containing the 7-azabicyclo[2.2.1]hept-2-ene ring system.
Journal: Bioorganic & medicinal chemistry letters 20120115
Title: 7-azabicyclo[2.2.1]heptane as a structural motif to block mutagenicity of nitrosamines.
Journal: Bioorganic & medicinal chemistry 20110415
Title: Asymmetric synthesis of 3,4-diaminocyclohexanol and endo-7-azabicyclo[2.2.1]heptan-2-amine.
Journal: Organic letters 20101105
Title: Water-stable helical structure of tertiary amides of bicyclic β-amino acid bearing 7-azabicyclo[2.2.1]heptane. Full control of amide cis-trans equilibrium by bridgehead substitution.
Journal: Journal of the American Chemical Society 20101027
Title: Mechanistic analysis of intramolecular free radical reactions toward synthesis of 7-azabicyclo[2.2.1]heptane derivatives.
Journal: The Journal of organic chemistry 20090605
Title: A novel intramolecular Ugi reaction with 7-azabicyclo[2.2.1]heptane derivatives followed by post-condensation acylations: a new entry to azanorbornyl peptidomimetics.
Journal: Organic & biomolecular chemistry 20090121
Title: 7-Azabicyclo[2.2.1]heptane as a unique and effective dialkylamino auxochrome moiety: demonstration in a fluorescent rhodamine dye.
Journal: Journal of the American Chemical Society 20081231
Title: Nonplanar structures of thioamides derived from 7-azabicyclo[2.2.1]heptane. Electronically tunable planarity of thioamides.
Journal: The Journal of organic chemistry 20081121
Title: Synthesis of heterocyclic analogues of epibatidine via 7-azabicyclo[2.2.1]hept-2-yl radical intermediates. 1. Intermolecular reactions.
Journal: The Journal of organic chemistry 20080905
Title: Structure-activity relationships of adenosines with heterocyclic N6-substituents.
Journal: Bioorganic & medicinal chemistry letters 20071215
Title: Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidine.
Journal: Journal of medicinal chemistry 20071213
Title: Synthesis of 7-azabicyclo[2.2.1]heptane and 2-oxa-4-azabicyclo[3.3.1]non-3-ene derivatives by base-promoted heterocyclization of alkyl N-(cis(trans)-3,trans(cis)-4-dibromocyclohex-1-yl)carbamates and N-(cis(trans)-3,trans(cis)-4-dibromocyclohex-1-yl)-2,2,2-trifluoroacetamides.
Journal: The Journal of organic chemistry 20071109
Title: Aza-Prins-pinacol approach to 7-azabicyclo[2.2.1]heptanes: syntheses of (+/-)-epibatidine and (+/-)-epiboxidine.
Journal: The Journal of organic chemistry 20071012
Title: Unusually high pyramidal geometry of the bicyclic amide nitrogen in a complex 7-azabicyclo[2.2.1]heptane derivative: Theoretical analysis using a bottom-up strategy.
Journal: The journal of physical chemistry. B 20050616
Title: aza-Prins-pinacol approach to 7-azabicyclo[2.2.1]heptanes and ring expansion to [3.2.1]tropanes.
Journal: Organic letters 20050331
Title: Cycloadditions of 2-azaallyllithium species with conjugated polyenes.
Journal: The Journal of organic chemistry 20040220
Title: An evaluation of amide group planarity in 7-azabicyclo[2.2.1]heptane amides. Low amide bond rotation barrier in solution.
Journal: Journal of the American Chemical Society 20031210
Title: Synthesis of enantiomerically pure 1,2-diamine derivatives of 7-azabicyclo[2.2.1]heptane. New leads as glycosidase inhibitors and rigid scaffolds for the preparation of peptide analogues.
Journal: The Journal of organic chemistry 20030711
Title: Synthesis and biological evaluation at nicotinic acetylcholine receptors of N-arylalkyl- and N-aryl-7-azabicyclo[2.2.1]heptanes.
Journal: Journal of medicinal chemistry 20020704
Title: Structural features of aliphatic N-nitrosamines of 7-azabicyclo[2.2.1]heptanes that facilitate N-NO bond cleavage.
Journal: Journal of the American Chemical Society 20011024
Title: Synthesis of n-heteroaryl-7-azabicyclo[2.2.1]heptane derivatives via palladium-bisimidazol-2-ylidene complex catalyzed amination reactions.
Journal: Organic letters 20010503
Title: exo-2-(Pyridazin-4-yl)-7-azabicyclo[2.2.1]heptanes: syntheses and nicotinic acetylcholine receptor agonist activity of potent pyridazine analogues of (+/-)-epibatidine.
Journal: Journal of medicinal chemistry 20010104
Title: [Nitrogen pyramidal amides and related compounds].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20010101